CN104983964A

CN104983964A - Traditional Chinese medicine for treating facial neuritis

Info

Publication number: CN104983964A
Application number: CN201510403982.3A
Authority: CN
Inventors: 包玲丽
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-07-10
Filing date: 2015-07-10
Publication date: 2015-10-21

Abstract

The invention relates to a traditional Chinese medicine for treating facial neuritis. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 20 parts of astragalus, 12 parts of rhizoma typhonii, 9 parts of stiff silkworm, 12 parts of atractylodes, 6 parts of gentiana macrophylla, 9 parts of earthworms and 9 parts of notopterygium roots. Clinic experiments prove that the traditional Chinese medicine can be used for safely and effectively treating the facial neuritis.

Description

A kind of Chinese medicine being used for the treatment of facial neuritis

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of facial neuritis.

Background technology

Facial neuritis is nervus facialis acute nonsuppurative inflammation in stylomastoid foramen, the common clinical of the infranuclear facial palsy caused, how because of local wind-engaging or catch a cold and onset.Facial neuritis belongs to motherland's medical science " very " category, and name " mouth is out-of-the-way ", is commonly called as facial paralysis.Chinese medicine is thought: primary disease is many because of positive QI-insufficiency, weakened defensive QI, ailment said due to cold or exposure people apoplex involving the channels and collaterals, and QI and blood numbness hinders, and runs smooth, caused by muscle arteries and veins loses and to support in honor.Vital QI being weakened and pathogen being violent is its main pathogenesis, so-called " gathering of heresy, its gas must be empty ".Facial neuritis main manifestations is: cause when core being organized (comprising cortex, cortex brainstem fibres, capsula interna, pons etc.) impaired, occur that focus offside face lower muscle is benumbed.Show as nasolabial fold from top to bottom to shoal, time grinningly, ptosis of labial angle (or title bicker is askew to focus side, facial muscle offside of namely paralysing), can not whistle and rouse the cheek.Cause for when nucleus of facial nerve or facial nerve damage, there is the whole facial muscle paralysis of focus homonymy, show as the volume that can not wrinkle from top to bottom, frown, close order, absent corneal reflex, nasolabial fold shoals, can not grinningly, drum the cheek, whistle, ptosis of labial angle (or claim bicker askew to focus offside, facial muscle offside of namely paralysing).

Medical material present Research involved in the present invention is as follows:

The Radix Astragali [another name] continuous stilbene, the continuous Radix Astragali.[source] this product is the dry root of leguminous plant Radix Astagali or Radix Astragali.Spring, Qiu Erji excavate, and removing fibrous root and root head, dry.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.[usage and dosage] takes orally: decoct soup, 9 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".

Rhizoma Typhonii [another name] Radix Aconiti Lateralis Preparata, Radix Aconiti Lateralis Preparata, Radix Aconiti Lateralis Preparata, Radix Aconiti Lateralis Preparata.[source] this product is the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx..Late June excavated to early August, and removing parent root, fibrous root and silt, practise and claim " mud Radix Aconiti Lateralis Preparata ", be processed into following kinds.[nature and flavor] are pungent, sweet, hot greatly; Poisonous.[return through] GUIXIN, kidney, spleen channel.[function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.[usage and dosage] takes orally: decoct soup, 3 ~ 15g.[attention] anemia of pregnant woman is forbidden.Should not with the Rhizoma Pinelliae, Fructus Trichosanthis, Radix Trichosanthis, Bulbus Fritillariae Uninbracteatae, Radix Ampelopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) with using.[extracts] " China's book on Chinese herbal medicine ".

Bombyx Batryticatus [another name] Bombyx Batryticatus, Bombyx Batryticatus, flying worm.[source] this product is that the larva in Bombycidae insecticide silkworm 4 ~ 5 age infects (or artificial vaccination) muscardine and lethal larva dry body.Produce more than spring, autumn, the silkworm died of illness by infection muscardine is dry.[nature and flavor] are salty, pungent, flat.[return through] returns liver, lung, stomach warp.[function cures mainly] expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, skin pruritus, submandibular lymph nodes is scorching, facial paralysis.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

The Rhizoma Atractylodis Macrocephalae [another name] Rhizoma Atractylodis Macrocephalae, winter art, Zhejiang art, kind art.[source] this product is the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Excavate when withered and yellow, the upper leaf of inferior leads in winter becomes fragile, removing silt, dries or dries, then remove fibrous root.[nature and flavor] are bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] deficiency of YIN is yearningly dry, and stagnation of QI feeling of distension and oppression person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".

Radix Gentianae Macrophyllae [another name] gentiana straminea, Gentiana dahurica, Radix Gentianae Marcrophyllae, western Radix Gentianae Marcrophyllae, a left side are turned round, a left side is twisted, RADIX GENTIANAE MACROPHYLLAE, RADIX GENTIANAE MACROPHYLLAE, Radix Raphani Macrophylla, plait Macrophylla.[source] this product is the dry root of gentianaceae plant Radix Gentianae Macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or Gentiana dahurica.First three kind practises title " Radix Gentianae Macrophyllae " and " gentiana straminea " respectively by character difference, and rear one is practised and claimed " Gentiana dahurica ".Spring, Qiu Erji excavate, removing silt; Radix Gentianae Macrophyllae and gentiana straminea shine soft, bank up " diaphoresis " to surface in reddish yellow or lark time, spread out and dry, or directly dry without " diaphoresis "; Rub de-black skin with the hands when Gentiana dahurica is taken advantage of fresh, dry.[nature and flavor] are pungent, bitter, flat.[return through] returns stomach, liver, gallbladder meridian.[function cures mainly] wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, and infantile malnutrition generates heat.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] be pain weakness with emaciation for a long time, and frequent micturition, just sliding person avoid clothes.[extracts] " China's book on Chinese herbal medicine ".

Pheretima [another name] Lumbricus, cricket earthworm, bent worm, native Dan, red worm.[source] this product is the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or the blind Pheretimatschiliensis of comb.Front one is practised and is claimed " LUMBRICUS ", practises title " Shanghai Pheretima " for latter three kinds.LUMBRICUS catches to autumn spring, and Shanghai Pheretima catches summer, cuts abdominal part open in time, and removing internal organs and silt are cleaned, dried or cold drying.[nature and flavor] are salty, cold.[return through] returns liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.[usage and dosage] takes orally: decoct soup, 4.5-9g.[attention] Deficiency and coldness of spleen and stomach should not take, and anemia of pregnant woman prohibits clothes.[extracts] " China's book on Chinese herbal medicine ".

Rhizoma Et Radix Notopterygii [another name] silkworm Qiang, RHIZOMA SEU RADIX NOTOPTERYGII, RHIZOMA SEU RADIX NOTOPTERYGII, Canis familiaris L. introduction flower, Koji.[source] this product is dry rhizome and the root of samphire Rhizoma Et Radix Notopterygii (back of the body wing celery) or Radix et Rhizoma Notopterygii.Spring, Qiu Erji excavate, and removing fibrous root and silt, dry.[nature and flavor] are pungent, bitter, temperature.[return through] returns bladder, kidney channel.[function cures mainly] cold expelling, dispels the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.

Thus [attention] headache due to deficiency of blood and pain osteodynia all over are with cold and heat person, this belongs to internal evidence, and misuse renvoi is done acute.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of facial neuritis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing facial neuritis.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a Chinese medicine for facial neuritis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 20 parts, Rhizoma Typhonii 12 parts, Bombyx Batryticatus 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Gentianae Macrophyllae 6 parts, Pheretima 9 parts, Rhizoma Et Radix Notopterygii 9 parts.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and facial neuritis patient 78 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 40 example and matched group 38 example at random, treatment group man 28 example, female 12 example, 19 ~ 60 years old age; Matched group man 26 example, female 12 example, 20 ~ 59 years old age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national facial neuritis clinical speciality a: part is that the nerve of Ipsilateral paralysis does not activate completely, and function does not recover left over part disease completely; Another part accepts damaging treatments and caused, concrete manifestation: without lifting eyebrow motion or to lift eyebrow low, large and small eye or eye upper eyelid relax, wrong on the corners of the mouth when lifting eyebrow, eye is little when affecting the corners of the mouth, drum mouth when closing one's eyes, and nasolabial fold is shallow, stiff, the stagnant food of face, sheds tears.Destroy because damaging treatments produces to body tissue cell, body will produce adhesion when recovering impaired organizing and cause interlock, also there will be large-area atrophy or hypertrophy.

2, test method

2.1 Therapeutic Method

The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.10 days courses for the treatment of.

Matched group oral prednisone sheet 10mg/ time, 4 times/day, 10 days courses for the treatment of.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Cure: clinical symptoms and sign disappear completely.

Effective: clinical symptoms and sign disappear substantially.

Effective: clinical symptoms and sign are all improved.

Invalid: clinical symptoms and sign are not improved.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Visible, the medicine that the present invention obtains can safe and effective treatment facial neuritis, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: the Radix Astragali 20 grams, Rhizoma Typhonii 12 grams, Bombyx Batryticatus 9 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Gentianae Macrophyllae 6 grams, Pheretima 9 grams, Rhizoma Et Radix Notopterygii 9 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of facial neuritis.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 2

Take: the Radix Astragali 20 grams, Rhizoma Typhonii 12 grams, Bombyx Batryticatus 9 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Gentianae Macrophyllae 6 grams, Pheretima 9 grams, Rhizoma Et Radix Notopterygii 9 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Embodiment 3

Take: the Radix Astragali 20 grams, Rhizoma Typhonii 12 grams, Bombyx Batryticatus 9 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Radix Gentianae Macrophyllae 6 grams, Pheretima 9 grams, Rhizoma Et Radix Notopterygii 9 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Claims

1. be used for the treatment of a Chinese medicine for facial neuritis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 20 parts, Rhizoma Typhonii 12 parts, Bombyx Batryticatus 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Gentianae Macrophyllae 6 parts, Pheretima 9 parts, Rhizoma Et Radix Notopterygii 9 parts.

2., as claimed in claim 1 for the Chinese medicine of facial neuritis, it is characterized in that, its preparation method is: take: the Radix Astragali 20 parts, Rhizoma Typhonii 12 parts, Bombyx Batryticatus 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Gentianae Macrophyllae 6 parts, Pheretima 9 parts, Rhizoma Et Radix Notopterygii 9 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. be used for the treatment of the Chinese medicine of facial neuritis as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 20 parts, Rhizoma Typhonii 12 parts, Bombyx Batryticatus 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Gentianae Macrophyllae 6 parts, Pheretima 9 parts, Rhizoma Et Radix Notopterygii 9 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. be used for the treatment of the Chinese medicine of facial neuritis as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 20 parts, Rhizoma Typhonii 12 parts, Bombyx Batryticatus 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Radix Gentianae Macrophyllae 6 parts, Pheretima 9 parts, Rhizoma Et Radix Notopterygii 9 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.