CN104982717A - Non-antibiotic daily ration feed additive premix for broiler chickens and usage method - Google Patents

Non-antibiotic daily ration feed additive premix for broiler chickens and usage method Download PDF

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Publication number
CN104982717A
CN104982717A CN201510341353.2A CN201510341353A CN104982717A CN 104982717 A CN104982717 A CN 104982717A CN 201510341353 A CN201510341353 A CN 201510341353A CN 104982717 A CN104982717 A CN 104982717A
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China
Prior art keywords
feed additive
additive premix
broiler chicks
broiler
premix
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Pending
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CN201510341353.2A
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Chinese (zh)
Inventor
孙全友
徐彬
王琳燚
闫祥洲
蔺萍
盛卫东
魏凤仙
李绍钰
白杰
郑新社
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Institute of Animal Husbandry and Veterinary Medicine of Henan Academy of Agricultural Sciences
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Institute of Animal Husbandry and Veterinary Medicine of Henan Academy of Agricultural Sciences
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Priority to CN201510341353.2A priority Critical patent/CN104982717A/en
Publication of CN104982717A publication Critical patent/CN104982717A/en
Pending legal-status Critical Current

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Abstract

The invention relates to non-antibiotic daily ration feed additive premix for broiler chickens. The non-antibiotic daily ration feed additive premix for the broiler chickens is composed of 10-20% of curcumin, 5-15% of xylooligosaccharide, 5-15% of bacillus licheniformis and 50-80% of carriers. A usage method of the non-antibiotic daily ration feed additive premix for the broiler chickens comprises the step that when broiler chicken feed is prepared, the non-antibiotic daily ration feed additive premix for the broiler chickens and the feed are mixed or evenly stirred according to the proportion of 1:1000. According to the non-antibiotic daily ration feed additive premix for the broiler chickens and the usage method, the composite effect of the curcumin, the xylooligosaccharide and the bacillus licheniformis is used to regulate the organism immunity and disease resistance of the broiler chickens, improve the egg laying productivity of the chickens and stimulate the growth potential of the chickens, and the significant effects are achieved. Animal tests prove that the premix can effectively replace antibiotics, the toxic and side effects such as the drug resistance and drug residues which occur after the antibiotics are used for a long time are avoided, and the healthy sustainable development of breeding industries and feed industries is facilitated.

Description

A kind of Broiler chicks nonreactive diet feed additive premix and using method
Technical field
The invention belongs to technical field of animal, particularly a kind of Broiler chicks nonreactive diet feed additive premix and using method.
Background technology
The industry that in broiler chicken Ye Shi China agricultural industry, the time in line with international standards the earliest, with the fastest developing speed, industrialization level is the highest.One high three low nutritional characteristics of the high protein of chicken, low fat, low in calories, low cholesterol become healthy meat product.But most of plant breeding environment of China is severe, medication is lack of standardization, and abuse of antibiotics and the residual problem of medicine drastically influence the development of China's Chicken industry, become " bottleneck " that must break through.
A kind of Broiler chicks nonreactive diet feed additive premix of the present invention uses the general principle of disease-resistant nutritive, eliminates the antigenic factor in feed.By the method for the nutrition regulations such as the natural plant extracts of feeding animals optimal dose, probiotics, humatite element and antioxidant vitamins be ensure chicken meat quality safely, improve the important technique measure of nutritive value and quality stability, the animal immune reaction that stress cause can be reduced decline, strengthen immunity and the premunition of animal body, this is to improving animal to utilization of nutrients, reduce the loss of Animal diseases, the security tool improving bird product is of great significance.
Summary of the invention
The object of the invention is to the deficiency overcoming above-mentioned existence, a kind of Broiler chicks nonreactive diet feed additive premix and using method are provided, for antibiotic medicine additive in alternative feed, regulate immunity of organisms and the premunition of Broiler chicks, improve its production performance, excite its growth potential.
In order to achieve the above object, technical scheme of the present invention is:
A kind of Broiler chicks nonreactive diet feed additive premix, is made up of the following component of weight percent meter: curcumin 10-20%, xylo-oligosaccharide 5-15%, bacillus licheniformis 5-15% and carrier 50-80%.
A kind of Broiler chicks nonreactive diet feed additive premix, is preferably made up of the following component of weight percent meter: curcumin 15%, xylo-oligosaccharide 10%, bacillus licheniformis 10% and carrier 65%.
Wherein, curcumin active ingredient actual content is 10%; Xylo-oligosaccharide active ingredient actual content is>=20%; In bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g; The corncob that carrier is cornstarch or pulverizes after drying.
Concrete using method is: when preparing Broiler chicks feed, and this Broiler chicks nonreactive diet feed additive premix and feed are mixed in the ratio of 1:1000 or stirred.
Curcumin is a kind of polyphenol compound extracted from the rhizome of Zingiber curcuma, has pharmacological action widely, as anti-inflammatory, anticancer, anti-oxidant etc.The physiological function of curcumin uniqueness makes it likely become a kind of Substitutes For Antibiotic of novel green, and the research on animal productiong also comes into one's own day by day, and research finds, adds production performance and immune performance that curcumin can improve many animals.
Xylo-oligosaccharide is the functional polymerization sugar be combined into β-Isosorbide-5-Nitrae glycosidic bond by 2-7 wood sugar molecule.It optionally can promote the proliferation activity of intestinal bifidobacteria.
After bacillus licheniformis enters enteron aisle, there is antagonism to the pathogenic bacteria such as staphylococcus, yeast-like fungus, and have growth promoting effects effect to Bifidobacterium, Bacillus acidi lactici, bacteroid, digestibility streptococcus, thus adjustable flora imbalance, reach therapeutic purposes.And bacillus licheniformis can impel body to produce antibacterial substance, kills pathogenic bacteria.In addition, bacillus licheniformis also makes enteron aisle anoxic by taking oxygen biological effect by force, be conducive to the growth of a large amount of anaerobic bacteria, cause enteron aisle low-oxygen environment, have facilitation to the growth and breeding of the wholesome anaerobic bacterias such as the Bifidobacterium in enteron aisle, Bacillus acidi lactici, bacteroid, digestibility streptococcus; Then antagonism is had to the pathogenic bacteria such as staphylococcus, yeast-like fungus.Can intestinal bacilli illness be adjusted by this double action, maintain body intestinal microecology balance, thus intestines problem is reached to the object for the treatment of and prevention.
beneficial effect of the present invention
The present invention uses the general principle of disease-resistant nutritive, and by using curcumin, the combined effect of xylo-oligosaccharide and bacillus licheniformis regulates immunity of organisms and the premunition of Broiler chicks, improves its production performance, excites its growth potential; Effectively can replace antibiotic, avoid the toxic and side effects such as the resistance to the action of a drug, drug resistance and the medicament residue that Long-Time Service antibiotic occurs.Broiler chicks nonreactive diet feed additive premix provided by the invention has following remarkable result:
1. improve average daily ingestion amount and the average daily gain of Broiler chicks significantly.As can be seen from the result of contrast test, premix of the present invention adds feed, and Broiler chicks average daily gain improves 8.28%, and average daily ingestion amount improves 9.16%, and feed-weight ratio reduces by 4.25%.
2. as can be seen from the result of contrast test, premix of the present invention adds feed, can promote the Development of Immune Organs of Broiler chicks, improves the Immune Organs Index of Broiler chicks, improve Broiler chicks periphery blood T lymphocyte and bone-marrow-derived lymphocyte conversion ratio, and then strengthen the immunologic function of Broiler chicks.
3. as can be seen from the result of contrast test, premix of the present invention adds feed, the vigor of superoxide dismutase in Broiler chicks serum and glutathione peroxidase can be significantly improved, reduce the content of MDA, thus improve the antioxidation of body.
4. significantly can reduce Broiler chicks enteron aisle pH value, the pH value of its duodenum, jejunum and ileum reduces by 7.19%, 2.42% and 7.38% respectively, is conducive to the breeding of beneficial bacterium, improves the micro-ecological environment of its enteron aisle.As can be seen from the result of contrast test, premix of the present invention adds feed, significantly can reduce the content of Escherichia coli and salmonella in broiler chicken caecum, significantly improve the content of Bacillus acidi lactici and Bifidobacterium.
Accompanying drawing explanation
Fig. 1 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds the effect diagram of feed to Broiler chicks average daily gain;
Fig. 2 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds the effect diagram of feed to Broiler chicks feed-weight ratio;
Fig. 3 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds the effect diagram of feed to the average daily ingestion amount of Broiler chicks;
Fig. 4 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds feed and affects table to Broiler chicks Immune Organs Index;
Fig. 5 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds feed and affects table to Broiler chicks PBLC conversion ratio;
Fig. 6 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds feed and affects table to Broiler chicks antioxygenic property;
Fig. 7 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds feed and affects table to Broiler chicks enteron aisle pH value;
Fig. 8 is that Broiler chicks nonreactive diet feed additive premix of the present invention adds feed and affects table to Broiler chicks cecum microorganisms.
Wherein, data of going together shown in Fig. 4 to Fig. 8 shoulder mark same letter or the person that do not take on mark represent difference significantly (P > 0.05), different letter representation significant difference (P < 0.05).
Detailed description of the invention
Embodiment 1
A kind of Broiler chicks nonreactive diet feed additive premix, is made up of the following component of weight percent meter: curcumin 10%, xylo-oligosaccharide 5%, bacillus licheniformis 5%, carrier 80%.
Wherein, curcumin active ingredient actual content is 10%; Xylo-oligosaccharide active ingredient actual content is>=20%; In bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g; Carrier is cornstarch.
Concrete using method is: when preparing Broiler chicks feed, and this Broiler chicks nonreactive diet feed additive premix and feed are mixed in the ratio of 1:1000 or stirred.
Embodiment 2
A kind of Broiler chicks nonreactive diet feed additive premix, is made up of the following component of weight percent meter: curcumin 10%, xylo-oligosaccharide 10%, bacillus licheniformis 10%, carrier 70%.
Wherein, curcumin active ingredient actual content is 10%; Xylo-oligosaccharide active ingredient actual content is>=20%; In bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g; Carrier is cornstarch.
Its using method is with embodiment 1.
Embodiment 3
A kind of Broiler chicks nonreactive diet feed additive premix, is made up of the following component of weight percent meter: curcumin 15%, xylo-oligosaccharide 10%, bacillus licheniformis 15%, carrier 60%.
Wherein, curcumin active ingredient actual content is 10%; Xylo-oligosaccharide active ingredient actual content is>=20%; In bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g; Carrier is the corncob pulverized after drying.
Its using method is with embodiment 1.
Embodiment 4
A kind of Broiler chicks nonreactive diet feed additive premix, is made up of the following component of weight percent meter: curcumin 20%, xylo-oligosaccharide 15%, bacillus licheniformis 15%, carrier 50%.
Wherein, curcumin active ingredient actual content is 10%.; Xylo-oligosaccharide active ingredient actual content is>=20%; In bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g; Carrier is the corncob pulverized after drying.
Its using method is with embodiment 1.
Embodiment 5
A kind of Broiler chicks nonreactive diet feed additive premix, is made up of the following component of weight percent meter: curcumin 15%, xylo-oligosaccharide 10%, bacillus licheniformis 10%, carrier 65%.
Wherein, curcumin active ingredient actual content is 10%; Xylo-oligosaccharide active ingredient actual content is>=20%; In bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g; Carrier is cornstarch.
Its using method is with embodiment 1.
Embodiment 6 contrast test
The healthy Broiler chicks of experimental selection 144 1 age in days AA+, be divided into 3 test group at random, each test group 6 repetition, each repetition 8, raise in cages for 3 layers in units of repeating, be respectively basal diet of feeding (control group), basal diet+antibiotic (processing 1 group) and basal diet+0.1% nonreactive feed addictive prescription (processing 2 groups), Diet Formula and trophic level are in table 1.Test chicken free choice feeding and drinking-water, experimental period is 42 days.Experimental result is shown in accompanying drawing.
Result of the test shows: process 2 groups and compare with control group with process 1 group, average daily gain improves 8.28% and 13.69% respectively, feed conversion rate is without significant difference, significantly improve Broiler chicks Immune Organs Index (P<0.05), the content (P<0.05) of Escherichia coli and salmonella in remarkable reduction broiler chicken caecum, processes 2 groups and process 1 group of there was no significant difference (P>0.05); Process the content (P<0.05) that 2 groups can significantly improve Bacillus acidi lactici and Bifidobacterium in addition, the PH(P<0.05 of remarkable reduction broiler chicken duodenum, jejunum and ileum), the content (P<0.05) of MDA in remarkable reduction Broiler chicks serum, improve the vigor (P<0.05) of total number born and glutathione peroxidase, significantly improve Broiler chicks periphery blood T lymphocyte and bone-marrow-derived lymphocyte conversion ratio (P<0.05).
In sum, known in conjunction with contrast test, premix of the present invention adds feed, obtains following remarkable result:
1. effectively improve the production performance of Broiler chicks, Broiler chicks average daily gain improves 8.28%, and average daily ingestion amount improves 9.16%, and feed-weight ratio reduces by 4.25%;
2. improve the immunity of organisms of Broiler chicks, be mainly manifested in Broiler chicks Immune Organs Index spleen, thymus gland and the bursa of farbricius and improve 36.36%, 5.77% and 33.33% respectively.Bone-marrow-derived lymphocyte conversion ratio and T lymphocyte transformation rate improve 26.97% and 111.59% respectively;
3. improve Broiler chicks body antioxygenic property, the content being mainly manifested in MDA in Broiler chicks serum reduces by 33.33%, the vigor of total number born and glutathione peroxidase improves 25.23% and 35.71% respectively;
4. improve the micro-ecological environment of Broiler chicks enteron aisle, improve body disease-resistant power.The pH value being mainly manifested in duodenum, jejunum and ileum reduces by 7.19%, 2.42% and 7.38% respectively; In caecum, the content of Escherichia coli and salmonella reduces by 40.70% and 43.85% respectively; The content of Bacillus acidi lactici and Bifidobacterium improves 8.74% and 39.83% respectively.
The present invention by using curcumin, the combined effect of xylo-oligosaccharide and bacillus licheniformis regulates immunity of organisms and the premunition of Broiler chicks, improve, excite its growth potential; Effectively can replace antibiotic, avoid the toxic and side effects such as the resistance to the action of a drug, drug resistance and the medicament residue that Long-Time Service antibiotic occurs; Be conducive to the sustainable health development of aquaculture and feed industry.

Claims (7)

1. a Broiler chicks nonreactive diet feed additive premix, is characterized in that: this premix is made up of the following component of weight percent meter: curcumin 10-20%, xylo-oligosaccharide 5-15%, bacillus licheniformis 5-15% and carrier 50-80%.
2. Broiler chicks nonreactive diet feed additive premix according to claim 1, it is characterized in that: preferred, this premix is made up of the following component of weight percent meter: curcumin 15%, xylo-oligosaccharide 10%, bacillus licheniformis 10% and carrier 65%.
3. the Broiler chicks nonreactive diet feed additive premix according to any one of claim 1-2, is characterized in that: described curcumin active ingredient actual content is 10%.
4. the Broiler chicks nonreactive diet feed additive premix according to any one of claim 1-2, is characterized in that: described xylo-oligosaccharide active ingredient actual content is >=20%.
5. the Broiler chicks nonreactive diet feed additive premix according to any one of claim 1-2, is characterized in that: in described bacillus licheniformis, viable bacteria total content is 2 × 10 10cFU/g.
6. the Broiler chicks nonreactive diet feed additive premix according to any one of claim 1-2, is characterized in that: the corncob that described carrier is cornstarch or pulverizes after drying.
7. the using method of the Broiler chicks nonreactive diet feed additive premix according to any one of claim 1-2, it is characterized in that: when preparing Broiler chicks feed, this Broiler chicks nonreactive diet feed additive premix and feed are mixed in the ratio of 1:1000, stirs.
CN201510341353.2A 2015-06-19 2015-06-19 Non-antibiotic daily ration feed additive premix for broiler chickens and usage method Pending CN104982717A (en)

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CN105219682A (en) * 2015-11-03 2016-01-06 山东省农业科学院生物技术研究中心 A kind of Bacillus licheniformis of substitute antibiotics fodder additives and application thereof
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CN105995147A (en) * 2016-05-26 2016-10-12 河南省农业科学院畜牧兽医研究所 Antibiotic-free daily feed additive premix for broiler chicken and using method of antibiotic-free daily feed additive premix
CN105995147B (en) * 2016-05-26 2019-06-07 河南省农业科学院畜牧兽医研究所 A kind of Broiler chicks nonreactive diet feed additive premix and its application method
CN106615923A (en) * 2016-11-24 2017-05-10 蚌埠市宗洼草鸡养殖农民专业合作社 Fodder for promoting quick growth of chicken
CN114854701A (en) * 2022-03-16 2022-08-05 福建福大百特生物科技有限公司 Microbe superoxide dismutase and coding gene thereof
CN114854701B (en) * 2022-03-16 2023-09-22 福建福大百特生物科技有限公司 Microbubble strain superoxide dismutase and encoding gene thereof

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Application publication date: 20151021