CN104971647A - Uniform reagent mixing apparatus, uniform reagent mixing assembly and analyzer - Google Patents
Uniform reagent mixing apparatus, uniform reagent mixing assembly and analyzer Download PDFInfo
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- CN104971647A CN104971647A CN201510406464.7A CN201510406464A CN104971647A CN 104971647 A CN104971647 A CN 104971647A CN 201510406464 A CN201510406464 A CN 201510406464A CN 104971647 A CN104971647 A CN 104971647A
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Abstract
The present invention relates to a uniform reagent mixing apparatus, a uniform reagent mixing assembly and an analyzer. The uniform reagent mixing apparatus comprises: a drive mechanism, wherein a reagent bottle can be placed on the drive mechanism and rotates along with the drive mechanism; and a transmission mechanism, wherein the first rotation axis line of the drive mechanism coincides with the second central axis line of the transmission mechanism, the drive mechanism can rotate around the first rotation axis line relate to the transmission mechanism, and the transmission mechanism first side wall facing the drive mechanism is provided with a driving part so as to match with the transmission part of the reagent bottle. According to the present invention, when the reagent bottle is placed on the drive mechanism, the drive mechanism rotates around the first rotation axis line, and the relative rotation is generated between the drive mechanism and the transmission mechanism, the driving part of the transmission mechanism drives the transmission part of the reagent bottle, such that the reagent bottle rotates around the first rotation axis line and rotates the self-axis line. In addition, the first side wall of the transmission mechanism is provided with a notch penetrating through the transmission mechanism.
Description
Technical field
The present invention relates to reagent evenly mixing device, particularly relate to the reagent evenly mixing device for in-vitro diagnosis detection field.The invention still further relates to reagent mixing assembly.
Background technology
In vitro in diagnositc analyser, the magnetic bead in reagent bottle is easy to precipitate under gravity, before therefore being taken out from reagent bottle by the reagent comprising magnetic bead, needs to mix magnetic bead.Can directly affect final reaction result because whether magnetic bead mixes, so before adding and getting reagent, need magnetic bead is in the state of fully mixing.
Traditional reagent evenly mixing device adopts the method rotating reagent bottle, but needs like this to increase power source.In addition, also have the method adopting and rock reagent bottle, this needs to increase power source equally, and in the structure of dish type evenly mixing device, this mode also not easily realizes.So, have employed the evenly mixing device of integral gear engagement at present.But, in the evenly mixing device that this integral gear engages, inconvenient when picking and placeing reagent bottle, easily cause reagent bottle to be stuck, and reagent evenly mixing device is not steady in the process run.
Summary of the invention
An object of the present invention is to provide the reagent evenly mixing device that can be easy to pick and place reagent bottle.Another object of the present invention is to provide can the reagent evenly mixing device of even running.
An aspect of of the present present invention relates to a kind of reagent evenly mixing device, it rotates to drive described reagent bottle for placing reagent bottle, described reagent bottle comprises driving section, this reagent evenly mixing device comprises: lead agency, reagent bottle can be placed on removedly on described lead agency and can to rotate with described lead agency, and wherein said lead agency has the first rotation; And transmission mechanism, described transmission mechanism has the second central axis, described first rotation and described second central axes, described lead agency can rotate relative to described transmission mechanism around described first rotation, described transmission mechanism has the first side wall towards described lead agency, and described the first side wall is provided with drive division to coordinate with the driving section of described reagent bottle.Described reagent evenly mixing device be configured to when described reagent bottle be placed on described lead agency, described lead agency around described first rotation rotate and produce relative rotation between described transmission mechanism with described lead agency time, the described drive division of described transmission mechanism drives the described driving section of described reagent bottle, described reagent bottle is rotated around described first rotation, and makes described reagent bottle rotate around the axis of self simultaneously.Described transmission mechanism is provided with the breach of the thickness running through described transmission mechanism at described the first side wall.
In mentioned reagent evenly mixing device, because transmission mechanism is provided with breach, can avoid or reduce reagent bottle and touch drive division in fetching process, thus be convenient to pick and place reagent bottle.Therefore, easily reagent bottle can be placed in reagent evenly mixing device according to the present invention and easily reagent bottle to be taken out from reagent evenly mixing device.
According to a preferred embodiment of the invention, described transmission mechanism is disk, and described lead agency is annulus, and described transmission mechanism is positioned at the inner ring of described lead agency.
According to a preferred embodiment of the invention, described drive division is the first teeth portion.When described driving section is the second teeth portion of the outer surface being arranged on described reagent bottle and described reagent bottle is placed on described lead agency, described first teeth portion and described second teeth portion can engage each other, and described reagent bottle can rotate around the axis of self under the engagement of described first teeth portion and described second teeth portion.
According to a preferred embodiment of the invention, described first teeth portion is provided with chamfering at the first surface place near described transmission mechanism, and described first surface is the surface of described transmission mechanism towards the direction contrary with reagent bottle installation direction.
According to a preferred embodiment of the invention, also comprise sensor, whether described sensor is in place for detecting described reagent bottle.By arranging sensor on reagent evenly mixing device, whether sensor can detect reagent bottle and be in place, if it is crooked to detect that reagent bottle occurs, is convenient to automatically follow-up or artificially and is adjusted to the right place by reagent bottle.In this case, when rotarily driving mechanism, when the driving section of reagent bottle and the drive division of transmission mechanism enter and engage, can not the phenomenon that gets stuck be produced, reagent evenly mixing device is run reposefully.
According to a preferred embodiment of the invention, described sensor be arranged on described transmission mechanism described first surface on described breach corresponding section.
An aspect of of the present present invention relates to a kind of reagent mixing assembly, and it comprises: reagent bottle, and described reagent bottle is provided with driving section; Lead agency, described reagent bottle to be placed on removedly on described lead agency and can to rotate with described lead agency, and described lead agency has the first rotation; And transmission mechanism, described transmission mechanism has the second central axis, described first rotation and described second central axes, described lead agency can rotate relative to described transmission mechanism around described first rotation, described transmission mechanism has the first side wall towards described lead agency, and described the first side wall is provided with drive division.Described reagent mixing component structure becomes when described lead agency is around described first rotation rotation and when producing relative rotation between described transmission mechanism with described lead agency, the described drive division of described transmission mechanism drives the described driving section of described reagent bottle, described reagent bottle is rotated around described first rotation, and makes described reagent bottle rotate around the axis of self simultaneously.Described transmission mechanism is provided with the breach of the thickness running through described transmission mechanism at described the first side wall.
According to a preferred embodiment of the invention, also comprise kit, described kit is arranged on described lead agency, and described kit offers container cavity to insert described reagent bottle.Described kit is configured to when described reagent bottle inserts in described kit, and the described driving section of described reagent bottle can expose, to coordinate with the described drive division of described transmission mechanism.
According to a preferred embodiment of the invention, described drive division is provided with chamfering at the first surface place near described transmission mechanism, and described first surface is the surface of described transmission mechanism towards the direction contrary with described reagent bottle installation direction.
According to a preferred embodiment of the invention, also comprise sensor, whether described sensor is in place for detecting described reagent bottle, wherein, with described breach corresponding section on the described first surface that described sensor is arranged on described transmission mechanism.
An aspect of of the present present invention relates to a kind of vitro diagnosis assays instrument, and it comprises the reagent evenly mixing device in above-mentioned any embodiment.
An aspect of of the present present invention relates to a kind of vitro diagnosis assays instrument, and it comprises the reagent mixing assembly in above-mentioned any embodiment.
Therefore, the invention provides and be a kind ofly easy to pick and place reagent bottle and can the reagent evenly mixing device of even running and reagent mixing assembly in blending process.
Accompanying drawing explanation
The feature of exemplary embodiment of the present, advantage and technique effect are described below with reference to the accompanying drawings.In the accompanying drawings, the element that identical symbology is identical, wherein:
Figure 1A is when illustrating that the drive division 105 of transmission mechanism 10 is meshed with the driving section 31 of reagent bottle 3, the top perspective view of reagent mixing assembly 100 according to an embodiment of the invention.
Figure 1B is when illustrating that the drive division 105 of transmission mechanism 10 is meshed with the driving section 31 of reagent bottle 3, the face upwarding stereogram of reagent mixing assembly 100 according to an embodiment of the invention.
Fig. 1 C is when illustrating that the drive division 105 of transmission mechanism 10 is meshed with the driving section 31 of reagent bottle 3, the top view of reagent mixing assembly 100 according to an embodiment of the invention.
Fig. 2 A is the amplification top perspective view of the part A in Figure 1A.
Fig. 2 B is the amplification face upwarding stereogram of the part B in Figure 1B.
Fig. 3 A is when illustrating that the driving section 31 of reagent bottle 3 is positioned at breach 106 place of transmission mechanism 10, the top perspective view of reagent mixing assembly 100 according to an embodiment of the invention.
Fig. 3 B is when illustrating that the driving section 31 of reagent bottle 3 is positioned at breach 106 place of transmission mechanism 10, the face upwarding stereogram of reagent mixing assembly 100 according to an embodiment of the invention.
Fig. 3 C is when illustrating that the driving section 31 of reagent bottle 3 is positioned at breach 106 place of transmission mechanism 10, the top view of reagent mixing assembly 100 according to an embodiment of the invention.
Fig. 4 A is the amplification top perspective view of the C part in Fig. 3 A.
Fig. 4 B is the amplification face upwarding stereogram of the D part in Fig. 3 B.
Detailed description of the invention
Detailed description of the invention according to reagent evenly mixing device of the present invention and reagent mixing assembly will be described by reference to the accompanying drawings.The detailed description and the accompanying drawings are below used for exemplarily principle of the present invention being described, the invention is not restricted to described preferred embodiment, scope of the present invention is defined by the claims.
In addition, space correlation term (such as " on ", D score, " left side " and " right side " etc.) for describing the relative position relation of element shown in the drawings and another element.Therefore, in directions different from direction shown in the drawings when space correlation term can be applied to use.Obviously, although for ease of illustrating, all these space correlation terms refer to direction shown in the drawings, and those skilled in the art can understand can use the direction different from the direction shown in accompanying drawing.
Below, will describe by reference to the accompanying drawings according to the reagent evenly mixing device of exemplary embodiment of the present invention and reagent mixing assembly.
Figure 1A-Fig. 1 C, Fig. 3 A-Fig. 3 C are the views that reagent mixing assembly 100 is according to an embodiment of the invention shown.Fig. 2 A and Fig. 2 B is the zoomed-in view that the part A of Figure 1A and the part B of Figure 1B are shown respectively.Fig. 4 A and Fig. 4 B is the zoomed-in view that the C part of Fig. 3 A and the D part of Fig. 3 B are shown respectively.
As shown in Figure 1A-Fig. 1 C, Fig. 3 A-Fig. 3 C, reagent mixing assembly 100 comprises: reagent evenly mixing device 1, kit 2 and reagent bottle 3.Reagent evenly mixing device 1 comprises transmission mechanism 10.Reagent evenly mixing device 1 also comprises lead agency (not shown).Figure 1A-Fig. 1 C, Fig. 3 A-Fig. 3 C also illustrate for the kit 2 be installed on reagent evenly mixing device 1 and the reagent bottle 3 be arranged in kit 2.
Lead agency is annulus, and is provided with kit for placing kit 2 and places position (not shown), and lead agency can hard to bear driving and rotating around the first rotation.Such as, the first rotation is positioned at the circle ring center of lead agency and vertical with ring textures.Such as, kit placement position arranges radially on the annulus of lead agency.The kit 2 being provided with reagent bottle 3 is placed in the kit placement position of lead agency, and together can rotate with lead agency by when driving and rotate at lead agency.
Transmission mechanism 10 is disk, and is arranged in the inner ring of lead agency.Transmission mechanism 10 has the second central axis 104, the second central axis 104 of transmission mechanism 10 and the first rotation axis coincident of lead agency.According to an embodiment, reagent evenly mixing device 1 is designed to, when lead agency is by when driving around the first rotation rotation, make to produce relative rotation between lead agency with transmission mechanism 10.Such as, transmission mechanism 10 can maintain static.Transmission mechanism 10 has upper surface 101, lower surface 102 and sidewall 103.As shown in Figure 1A and Fig. 3 A, when kit 2 and reagent bottle 3 are installed along direction from top to bottom, upper surface 101 is towards the surface in the direction contrary with kit 2 installation direction, and the surface relative with upper surface 101 of transmission mechanism 10 is lower surface 102.Sidewall 103 is provided with drive division 105.According to an embodiment, drive division 105 is the gear teeth be arranged in along the periphery of transmission mechanism 10 on sidewall 103.The diameter of transmission mechanism 10 is constructed such that transmission mechanism 10 can be accommodated in the inner ring of lead agency, and the reagent bottle 3 when the kit 2 being provided with reagent bottle 3 rotates with lead agency can be contacted with the drive division 105 of transmission mechanism 10 and can rotate under the driving of drive division 105.Such as, the diameter of transmission mechanism 10 is about 120-300mm.Such as, the thickness of transmission mechanism 10 is about 8-10mm.
Kit 2 is for holding one or more reagent bottle 3.Kit 2 has at least one container cavity, and reagent bottle 3 can be inserted in the container cavity of kit 2.Such as, kit 2 has three container cavities 21,22 and 23, as shown in figures ia-c.The higher reagent bottle 3 of mixing requirement is held, such as magnetic bead bottle closer to the container cavity 23 of transmission mechanism 10 for inserting when kit 2 is installed on reagent evenly mixing device 1.Container cavity 23 is configured so that when kit 2 is installed to reagent evenly mixing device 1, driving section 31 (described below) being inserted into the reagent bottle 3 in container cavity 23 can engage with the drive division 105 of transmission mechanism 10, and reagent bottle 3 can be rotated around the rotation of himself in container cavity 23.
According to an embodiment, container cavity 23 is configured with opening, makes when reagent bottle 3 is placed in container cavity 23, and the driving section 31 of reagent bottle 3 can be exposed out and can engage with the drive division 105 of transmission mechanism 10.Preferably, container cavity 23 is configured to through hole, makes when reagent bottle 3 is placed in container cavity 23, and the driving section 31 be positioned at bottom reagent bottle 3 can be exposed out from the bottom of container cavity 23 and can engage with the drive division 105 of transmission mechanism 10.More preferably, container cavity 23 is configured to not exclusively surround reagent bottle 3 when reagent bottle 3 is placed in container cavity 23, make the outer surface 32 of demasking reagent bottle 3 at least partially, reduce the frictional force between outer surface 32 and container cavity 23 thus when reagent bottle 3 rotates around the rotation of self.
When kit 2 is installed to reagent evenly mixing device 1, also reagent bottle can be held relative to container cavity 23 away from the container cavity 21 and 22 of transmission mechanism 10, such as, according to the reagent bottle of reagent bottle 3 of the present invention or other types, as shown in figures ia-c.
Reagent bottle 3 has cavity, and can be used in holding chemical reagent, such as, comprises the reagent of magnetic bead.Reagent bottle 3 is provided with driving section 31, for when the kit 2 that reagent bottle 3 is housed is installed in reagent evenly mixing device 1, engages with the drive division 105 of transmission mechanism 10.According to an embodiment, driving section 31 is set in the bottom of reagent bottle 3.According to an embodiment, driving section 31 is for being arranged on the gear teeth in a part for the outer surface 32 of reagent bottle 3.When reagent bottle 3 is inserted in the container cavity 23 of kit 2, the driving section 31 of reagent bottle 3 can expose, and make when the kit 2 being inserted with reagent bottle 3 is placed into kit placement position, driving section 31 and drive division 105 engage each other.When producing relative rotation between lead agency with transmission mechanism 10, drive division 105 drives the driving section 31 of reagent bottle 3, and reagent bottle 3 can be rotated around himself rotation in the container cavity 23 of kit 2.
As mentioned above, reagent mixing assembly 100 is configured to according to an embodiment of the invention: transmission mechanism 10 is arranged in the inner ring of lead agency, the kit 2 being provided with reagent bottle 3 is placed on the kit placement position of lead agency, and the drive division 105 of transmission mechanism 10 and the driving section 31 of reagent bottle 3 cooperatively interact, as shown in figures ia-c simultaneously.
When using the reagent in reagent mixing assembly 100 pairs of reagent bottles 3 to mix, transmission mechanism 10 maintains static, and lead agency is driven to rotate around the first rotation.When lead agency rotates around the first rotation, lead agency drives the reagent bottle 3 that it is placed to rotate around the first rotation, and meanwhile, the drive division 105 due to transmission mechanism 10 drives the driving section 31 of reagent bottle 3, reagent bottle 3 rotates around the rotation of himself.Reagent mixing assembly 100 according to an embodiment of the invention, drive division 105 and driving section 21 adopt the mode of gears meshing to mix reagent, and structure is simple.In addition, owing to having the mode of said gear engagement, reagent bottle 3 also carries out rotation around the rotation of reagent bottle 3 self while the first rotation around lead agency carries out revolving round the sun, and makes it possible to fully mix the reagent in reagent bottle 3.
In addition, transmission mechanism 10 is provided with the breach 106 of the thickness running through transmission mechanism 10 at sidewall 103, makes to be convenient to pick and place reagent bottle 3.Particularly, breach 106 is the shape inwardly concaved from the sidewall 103 of transmission mechanism 10.(" L " becomes can avoid when breach 106 place picks and places reagent bottle 3 with profile design the driving section 31 of reagent bottle 3 to contact with the drive division 105 of transmission mechanism 10 and interferes the length of breach 106 as shown in Figure 1 C).As shown in Figure 1 C, when observing from top view, the contour shape of breach 106 can be circular arc, elliptic arc, curve, broken line or above-mentioned every any combination.Such as, the length of breach 106 is greater than the diameter of driving section 31.Preferably, the length of breach 106 can be about 28-35mm.Preferably, drive division 105 is not set at breach 106 place.If sidewall 103 does not arrange breach 106, when picking and placeing reagent bottle 3, the gear teeth of driving section 31 and drive division 105 easily touch interference, cause reagent bottle 3 to be stuck, and make pick and place inconvenient and need manually adjustment.On the contrary, because sidewall 103 is provided with breach 106, when picking and placeing reagent bottle 3 at breach 106 place, the problem that driving section 31 and drive division 105 there will not be touching to interfere, makes to pick and place conveniently.
In addition, drive division 105 is provided with chamfering at upper surface 101 place near transmission mechanism 10.By arranging chamfering, when reagent bottle 3 is driven the drive division 105 intermeshing position (as shown in figures ia-c) of driving section 31 with transmission mechanism 10 moving to reagent bottle 3 from the position (as shown in figs. 3 a-3 c) being positioned at breach 106, driving section 31 and drive division 105 more successfully can enter engagement.In addition, when reagent bottle 3 be driven to move to from driving section 31 and the intermeshing position of drive division 105 (as shown in figures ia-c) of transmission mechanism 10 reagent bottle 3 be positioned at the position (as shown in figs. 3 a-3 c) of breach 106 time, driving section 31 and drive division 105 more successfully can depart from engagement.
In addition, reagent evenly mixing device 1 also comprises sensor 12, and whether sensor 12 is in place for detecting reagent bottle 3 when reagent bottle 3 being installed to reagent evenly mixing device 1.Such as, the upper surface 101 of transmission mechanism 10 arranges sensor 12.Preferably, sensor 12 is arranged on position corresponding with breach 106 on upper surface 101.Such as, sensor 12 is photoelectric sensor.When the kit 2 being provided with reagent bottle 3 being placed into kit and placing position, reagent bottle 3 easily occurs crooked.When reagent bottle 3 occurs crooked, the Blending Efficiency of Blending of reagent can be affected, and the driving section 31 of reagent bottle 3 may be caused with the drive division 105 of transmission mechanism 10 to engage bad and clamping stagnation, thus it is steady that reagent evenly mixing device 1 is run, and even cannot realize predetermined Blending Efficiency of Blending.Reagent bottle 3 can be detected whether be in place by arranging sensor 12 on reagent evenly mixing device 1, and then automatically or manually adjust the position of reagent bottle 3 according to the testing result of sensor 12, reagent bottle 3 is correctly placed.In this case, driving section 31 can realize engaging with drive division 105 smoothly, and making reagent mix assembly 100 can even running.Preferably, by arranging sensor 12 with breach 106 corresponding section, can be detected it while placement reagent bottle 3 and whether be in place, thus minimizing reagent bottle 3 picking and placeing the time shared by adjustment, improves operating efficiency.
As previously mentioned, although be illustrated exemplary embodiment of the present invention with reference to accompanying drawing in illustrating, the invention is not restricted to above-mentioned each detailed description of the invention, other way of example many can also be had.
Hereinbefore, describe and reagent bottle 3 is placed in kit 2 and kit 2 is arranged on the embodiment on reagent evenly mixing device 1.But those skilled in the art are to be understood that and the present invention is not limited thereto.Such as, reagent bottle 3 can directly be installed on the lead agency of reagent evenly mixing device 1, and does not need to use kit 2.In this case, reagent evenly mixing device 1 is designed so that the driving section 31 of reagent bottle 3 can engage with the drive division 105 of transmission mechanism 10.
Hereinbefore, for transmission mechanism 10 be disk, lead agency is for annulus and the inner ring that transmission mechanism 10 is positioned at lead agency describes the structure of reagent evenly mixing device 1.But, it will be appreciated by those skilled in the art that in reagent evenly mixing device 1, transmission mechanism 10 is not limited thereto with the set-up mode of lead agency.Such as, transmission mechanism can be designed to annulus, and lead agency can be arranged on the inner ring of transmission mechanism.Under such a configuration, transmission mechanism has madial wall and lateral wall.The interior sidewall surface of transmission mechanism places position to the kit on lead agency.The madial wall of transmission mechanism is provided with drive division, and drive division such as comprises the gear teeth.When reagent bottle 3 is installed on lead agency, the drive division of transmission mechanism can engage with the driving section of reagent bottle 3, and when lead agency rotates relatively relative to transmission mechanism, reagent bottle 3 can be driven to rotate around its own rotation axis line.In addition, transmission mechanism can be provided with the breach of the thickness running through transmission mechanism at madial wall, makes to be convenient to pick and place reagent bottle 3.
Hereinbefore, describe by gear teeth meshing the embodiment that reagent bottle realizes rotation for drive division 105 and driving section 31.But, it will be appreciated by those skilled in the art that the fit system between drive division and driving section is not limited thereto.Such as, drive division 105 can drive driving section 31 by other means, rotates around its own rotation axis line to realize reagent bottle 3.Such as, drive division 105 can be the first friction part, and driving section 31 can be the second friction part, and drive division 105 can drive driving section 105 under the effect of frictional force, rotates around its own rotation axis line to realize reagent bottle 3.
Hereinbefore, describe lead agency can to rotate and transmission mechanism 10 keeps fixing detailed description of the invention.But, it will be appreciated by those skilled in the art that and the present invention is not limited thereto.Such as, transmission mechanism 10 also can rotate, as long as meet transmission mechanism 10 and there is relative rotation between lead agency, making can be fitted to each other between the drive division 105 of transmission mechanism 10 and the driving section 31 being placed on the reagent bottle 3 on lead agency realizes reagent bottle 3 and rotates around its own rotation axis line.Such as, when lead agency and transmission mechanism 10 can rotating Vortexes, the rotary speed of lead agency is greater than or less than the rotary speed of transmission mechanism 10.Such as, lead agency and transmission mechanism 10 can reversely rotate.
Hereinbefore, the detailed description of the invention that driving section 31 is arranged on the bottom of reagent bottle 3 is given.But it will be appreciated by those skilled in the art that, driving section 31 can be arranged on other position of reagent bottle 3, as long as it can realize coordinating with the drive division 105 of transmission mechanism 10.Such as, driving section 31 can be arranged on the top of reagent bottle 3 or the centre at reagent bottle 3.
Hereinbefore, give, at drive division 105, upper surface 101 place of transmission mechanism 10 is provided with the detailed description of the invention of chamfering.But, additionally or alternatively, at drive division 105, chamfering can be set near lower surface 103 place of transmission mechanism 10, drive division 105 can be entered more swimmingly with driving section 31 and engage.
Hereinbefore, the detailed description of the invention that sensor 12 is photoelectric sensor is given.But it will be appreciated by those skilled in the art that, sensor 12 also can be the sensor of other types, as long as it can detect whether reagent bottle 3 is in place.Such as, sensor 12 can be electromagnetic sensor, Hall element, laser sensor etc.
Hereinbefore, the detailed description of the invention with breach 106 corresponding section on upper surface 101 that sensor 12 is arranged on transmission mechanism 10 is given.But it will be appreciated by those skilled in the art that, sensor 12 can be positioned at and can detect other position whether reagent bottle 3 be in place outside above-mentioned position.
The present invention also provides a kind of vitro diagnosis assays instrument, and it comprises reagent evenly mixing device as above or reagent mixing assembly.In addition, vitro diagnosis assays instrument according to the present invention can also comprise cooling system, Load System, sample adding system etc.Those skilled in the art are further appreciated that mixing assembly according to reagent evenly mixing device of the present invention and reagent can be applied to other chemistry or biological analysers.
As previously mentioned, although be illustrated exemplary embodiment of the present invention with reference to accompanying drawing in illustrating, the invention is not restricted to above-mentioned detailed description of the invention, scope of the present invention should be limited by claims and equivalents thereof.
Claims (12)
1. a reagent evenly mixing device, it rotates to drive described reagent bottle for placing reagent bottle, and described reagent bottle comprises driving section, and described reagent evenly mixing device comprises:
Lead agency, described reagent bottle can be placed on removedly on described lead agency and can to rotate with described lead agency, and wherein said lead agency has the first rotation; And
Transmission mechanism, described transmission mechanism has the second central axis, described first rotation and described second central axes, described lead agency can rotate relative to described transmission mechanism around described first rotation, described transmission mechanism has the first side wall towards described lead agency, described the first side wall is provided with drive division to coordinate with the described driving section of described reagent bottle
Wherein, described reagent evenly mixing device be configured to when described reagent bottle be placed on described lead agency, described lead agency around described first rotation rotate and produce relative rotation between described transmission mechanism with described lead agency time, the described drive division of described transmission mechanism drives the described driving section of described reagent bottle, described reagent bottle is rotated around described first rotation, and make described reagent bottle rotate around the axis of self simultaneously
Wherein, described transmission mechanism is provided with the breach of the thickness running through described transmission mechanism at described the first side wall.
2. reagent evenly mixing device according to claim 1, wherein, described transmission mechanism is disk, and described lead agency is annulus, and described transmission mechanism is positioned at the inner ring of described lead agency.
3. reagent evenly mixing device according to claim 2, wherein, described drive division is the first teeth portion, and
Wherein, when described driving section is the second teeth portion of the outer surface being arranged on described reagent bottle and described reagent bottle is placed on described lead agency, described first teeth portion and described second teeth portion can engage each other, and described reagent bottle can rotate around the axis of self under the engagement of described first teeth portion and described second teeth portion.
4. reagent evenly mixing device according to claim 3, wherein, described first teeth portion is provided with chamfering at the first surface place near described transmission mechanism, and described first surface is the surface of described transmission mechanism towards the direction contrary with described reagent bottle installation direction.
5. reagent evenly mixing device according to claim 4, also comprises sensor, and whether described sensor is in place for detecting described reagent bottle.
6. reagent evenly mixing device according to claim 5, wherein, with described breach corresponding section on the described first surface that described sensor is arranged on described transmission mechanism.
7. a reagent mixing assembly, it comprises:
Reagent bottle, described reagent bottle is provided with driving section;
Lead agency, described reagent bottle to be placed on removedly on described lead agency and can to rotate with described lead agency, and described lead agency has the first rotation; And
Transmission mechanism, described transmission mechanism has the second central axis, described first rotation and described second central axes, described lead agency can rotate relative to described transmission mechanism around described first rotation, described transmission mechanism has the first side wall towards described lead agency, described the first side wall is provided with drive division
Wherein, described reagent mixing component structure becomes when described lead agency is around described first rotation rotation and when producing relative rotation between described transmission mechanism with described lead agency, the described drive division of described transmission mechanism drives the described driving section of described reagent bottle, described reagent bottle is rotated around described first rotation, and make described reagent bottle rotate around the axis of self simultaneously
Wherein, described transmission mechanism is provided with the breach of the thickness running through described transmission mechanism at described the first side wall.
8. reagent mixing assembly according to claim 7, also comprise kit, described kit is arranged on described lead agency, and described kit offers container cavity to insert described reagent bottle,
Wherein, described kit is configured to when described reagent bottle inserts in described kit, and the described driving section of described reagent bottle can expose, to coordinate with the described drive division of described transmission mechanism.
9. reagent mixing assembly according to claim 8, wherein, described drive division is provided with chamfering at the first surface place near described transmission mechanism, and described first surface is the surface of described transmission mechanism towards the direction contrary with described reagent bottle installation direction.
10. reagent according to claim 9 mixing assembly, also comprise sensor, whether described sensor is in place for detecting described reagent bottle, wherein, with described breach corresponding section on the described first surface that described sensor is arranged on described transmission mechanism.
11. 1 kinds of vitro diagnosis assays instrument, it comprises the reagent evenly mixing device according to any one of claim 1-6.
12. 1 kinds of vitro diagnosis assays instrument, it comprises the reagent mixing assembly according to any one of claim 7-10.
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| CN201510406464.7A CN104971647A (en) | 2015-07-10 | 2015-07-10 | Uniform reagent mixing apparatus, uniform reagent mixing assembly and analyzer |
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| US11255846B2 (en) | 2017-03-01 | 2022-02-22 | Leadway (Hk) Limited | Reagent mixing and conveying device and reagent mixing method |
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| CN107462578A (en) * | 2017-09-21 | 2017-12-12 | 河北华厚天成环保技术有限公司 | A kind of Water Test Kits |
| CN107860932A (en) * | 2017-10-23 | 2018-03-30 | 迪瑞医疗科技股份有限公司 | A kind of reagent evenly mixing device and method |
| CN110554181A (en) * | 2018-05-30 | 2019-12-10 | 深圳市帝迈生物技术有限公司 | Kit and reagent dish device |
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| CN112697570B (en) * | 2020-11-27 | 2024-04-12 | 迈克医疗电子有限公司 | Test tube taking and placing mixing device and sample analyzer |
| CN113058468A (en) * | 2021-04-09 | 2021-07-02 | 深圳市汇知科技有限公司 | Extraction equipment for detecting high-molecular chemical reagent and extraction process thereof |
| CN113058468B (en) * | 2021-04-09 | 2023-10-17 | 北京同禧科技有限公司 | Extraction equipment and extraction process for detecting high molecular chemical reagent |
| WO2022227724A1 (en) * | 2021-04-28 | 2022-11-03 | 深圳市亚辉龙生物科技股份有限公司 | Reagent mixing and loading device and immunological detection apparatus |
| CN114904430A (en) * | 2022-04-12 | 2022-08-16 | 深圳雷杜生命科学股份有限公司 | Blending device and analysis equipment |
| CN114910657A (en) * | 2022-07-15 | 2022-08-16 | 山东第一医科大学第一附属医院(山东省千佛山医院) | Anal secretion detection device |
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Address after: 611731 4 Building 8, two road, Chengdu, Sichuan Applicant after: Mike Medical Electronics Ltd Address before: High tech Zone Chengdu city Sichuan province 611731 rivers Road No. 16 Building 1 layer 5 Applicant before: SICHUAN MAKER BIOMEDICAL ELECTRONIC CO., LTD. |
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Application publication date: 20151014 |