CN104958693B - Treat the Chinese medicine of the proliferation of mammary gland - Google Patents
Treat the Chinese medicine of the proliferation of mammary gland Download PDFInfo
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- CN104958693B CN104958693B CN201510325133.0A CN201510325133A CN104958693B CN 104958693 B CN104958693 B CN 104958693B CN 201510325133 A CN201510325133 A CN 201510325133A CN 104958693 B CN104958693 B CN 104958693B
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Abstract
A kind of Chinese medicine for treating the proliferation of mammary gland, it is characterised in that be made by following raw material medicinal material formulas：5~15 parts of Prunella vulgaris, 15~25 parts of safflower, 15~25 parts of Radix Salviae Miltiorrhizae, 5~15 parts of spina gleditsiae, 10~20 parts of Radix Glycyrrhizae, 5~15 parts of Radix Angelicae Sinensis, 5~15 parts of radix paeoniae rubra, 5~15 parts of radix bupleuri, 10~20 parts of Radix Curcumae.The present invention treats the Chinese medicine of the proliferation of mammary gland, and advantages and beneficial effects are：It can dispersing liver and promoting blood circulation, softening and resolving hard mass, swelling and pain relieving；It is depressed for liver depression, the proliferation of mammary gland caused by qi depression to blood stasis, newborn core tubercle, distending pain；Its prescription is scientific and reasonable, and compatibility is original, significant in efficacy；Have treating both manifestation and root cause of disease, have no toxic side effect, is quick, the features such as difficulty in relapse after healing, be treat the proliferation of mammary gland, newborn core tubercle good Chinese medicine；Its production method is simple, at low cost, and private clinic evolution is suitble to cure the disease, and also is adapted for situation of all-level hospitals preparation and pharmaceutical factory's production.
Description
Technical field
The present invention relates to a kind of Chinese medicines, more particularly to a kind of Chinese medicine for treating the proliferation of mammary gland significant in efficacy.
Background technology
The proliferation of mammary gland is most common women's diseases, and incidence accounts for the first place of mammary gland disease, has been mainly in the menstrual cycle
Women, incidence is about between 40%~50%；The variation of its basic pathology is the hyperplasia of mammary gland constituent, in structure, number
Exception is shown on amount and tissue morphology, is substantially a kind of physiology hyperplasia and mammary gland normal configuration caused by subinvolution
It is disorderly；Due to having the possibility for developing into breast cancer after the seriously ill patient of the sub-fraction proliferation of mammary gland, so it is believed that
Cyclomastopathy is " precancerous lesion " of breast cancer.The proliferation of mammary gland belongs to " newborn addiction " scope in traditional Chinese medicine, the name of newborn addiction first appeared in
Huatuo《Huatuo's Zhongzang classic》；《Surgery is authentic》" newborn addiction is mammary nodule to cloud, and shaped like ball ovum, or pendant is had a pain again, or not bitterly, color of the leather is not
Become；Its core is joined in charitable and pious deeds anger growth and decline, and mostly by worry impairing spleen, the angry impariment of the liver, pent-up forms ".Dou Hanqing《Sore experience pandect》Cloud " newborn addiction
This disease, because of woman 15 years old, passages through which vital energy circulates will go or two row in January, or to cross the moon not all right, caused this raw disease ".Woman nipple category liver, breast
Room category stomach, The spleen and the stomach are interior-exteriorly related, and liver happiness item reaches, if anxiety and rage, liver dysfunction, spleen is damaged；Lead to the stagnation of the circulation of vital energy phlegm blood coagulation stasis of blood, then
There is breast caking pain；CHONG meridian being the blood pool again, REN meridian connecting with the uterus and pregnancy, two through follow abdomen and whereabouts in the heart, the kidney channel of foot-Shaoyin, above pass through liver diaphragm and
Join with breast, rushes wantonly two arteries and veins and be under the jurisdiction of liver kidney, Chong and Ren channel disorder, mental disorder pent-up, kidney deficiency and liver, deficiency of yang phlegm wet is interior to be tied, and it is swollen breast occur
Block pain, and with change in menstrual cycle.Traditional Chinese medicine think the growth, development and secreting function of Normal breast all with internal organs,
The physiological function of channels and collaterals, qi and blood etc. is closely related；It adheres to congenital essence-QI, by the institute of vital organs of the human body twelve meridians blood body fluid
It supports, occurs the profit and loss variation of different times with the prosperity and decline of vital essence in woman；And physiological function again with menstruation, tire is pregnant, delivery and feed infant it
Between connect each other；Though therefore breast belongs to local organs, pass through contact in length and breadth and the inherent internal organs of the twelve regular channels and eight extra-channel
An organic whole is formd, and its functional activity is completed by the effect of essence, gas, blood, body fluid.Proliferation of mammary gland mechanism is multiple
It is miscellaneous, symptoms of varying severity, deficient and excessive syndromes appearing together；This organic conception and the understanding of modern medicine are consistent, and discuss mammary gland
The theoretical foundation of hyperplasia pathogensis.
The classical symptom of the proliferation of mammary gland is breast pain, lump in breast, nipple discharge, disorderly according to cyclomastopathy endocrine
Random pathogenesis；Western medicine cyclomastopathy is to adjust ovarian endocrine or block hormonal action target spot, blocks morbidity ring
Section alleviates symptom, therefore mostly uses the therapeutic scheme for inhibiting estrogen drugs.Its Western medicine has：1. tamoxifen (tamoxifen
It is fragrant) class：It is a kind of antiestrogen of nonsteroidal for estrogen receptor antagon, is widely used in treating the proliferation of mammary gland,
It is current most effective medicine；Main mechanism is the estrogen receptor with estrogen competitive binding target cell, directly
Estrogen receptor is closed, the effect of estrogen is blocked.Most of case breast pain can also recur after drug withdrawal, and side effect is dry
Menstruation is disturbed, shows as menses reduction, menstruation is postponed or in advance, endometrial thickness is apparent, menoxenia；It takes for a long time, and has
Dramatically increase the risk for suffering from carcinoma of endometrium；In addition Toremifene Citrate (fareston) has similar pharmacology with tamoxifen
Effect and adverse reaction.2. bromocriptine class Dopaminergic Agents：The secretion for inhibiting tethelin prolactin(PRL, without influencing
Other pituitrins can be used for treating by the excessively high caused various illnesss of prolactin(PRL, inhibit or reduce prolactinoma, restore corpus luteum
The normal secretions of element are generated, galactocele or the quantity and volume of brief summary is reduced, mitigates caused by progestogen/estrogen imbalance
Breast pain；The side effect of this medicine is dizzy sleepy, GI irritation, prosopospasm, illusion, dyskinesia etc..3. steroids
Drug：Such as progesterone, testosterone propionate, danazol, such drug main function mechanism are to utilize androgen or progestational hormone pair
The anti-estrogen increased；To adjust the balance of internal estrogen and progestogen level, mitigate pain, softens tubercle；But oneself is seldom at present
Using such drug as the routine administration for treating this disease, because while hormone therapy initial performances are pretty good, but when due to treating
The amount and application time of input hormone are difficult the needs of snugly this suitable disease, often there is the disadvantage exceeded the proper limits in righting a wrong；Using
It is improper, it will certainly more aggravate this unbalance state.
Invention content
Side effect and motherland's traditional Chinese medicine in view of Western medicine are to the theoretical foundation of the pathogensis of the proliferation of mammary gland, in conjunction with invention
Clinical practice and research of the people to the proliferation of mammary gland；Medicinal material in selected motherland's medical treasure-house carries out reasonable formula, provides one kind and control
Treat the Chinese medicine of the proliferation of mammary gland；Its compatibility is original, significant in efficacy, can effectively solve the problems, such as the treatment of the proliferation of mammary gland；Its toxic side effect
It is small, control that recurrence rate after healing is low, and cheap, patient is easily accepted by.
The present invention treats the Chinese medicine of the proliferation of mammary gland, it is characterised in that is made by following raw material medicinal material formulas：
5~15 parts of Prunella vulgaris, 15~25 parts of safflower, 15~25 parts of Radix Salviae Miltiorrhizae, 5~15 parts of spina gleditsiae, 10~20 parts of Radix Glycyrrhizae, when
Return 5~15 parts, 5~15 parts of radix paeoniae rubra, 5~15 parts of radix bupleuri, 10~20 parts of Radix Curcumae.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and preferred weight part of raw medicinal material formula is：
10 parts of Prunella vulgaris, 20 parts of safflower, 20 parts of Radix Salviae Miltiorrhizae, 10 parts of spina gleditsiae, 15 parts of Radix Glycyrrhizae, 10 parts of Radix Angelicae Sinensis, 10 parts of radix paeoniae rubra, bavin
10 parts recklessly, 15 parts of Radix Curcumae.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and dosage form is pill.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and dosage form can be any type peroral dosage form described in pharmacy.
It is as follows the effect of each raw medicinal material in the present invention：
Prunella vulgaris：Return liver, gallbladder channel, clear liver and improve vision, powder detoxifcation；Cure mainly scrofula, goiter and tumor, acute mastitis, carbuncle furuncle poison.
Safflower：Converge to heart and liver channels, invigorate blood circulation, stasis-dispelling and pain-killing；For amenorrhoea, dysmenorrhoea, lochia, abdominal mass lump in the abdomen, bruise
Damage, hemorrhoid gall.
Radix Salviae Miltiorrhizae：Enter the heart, Liver Channel, have promoting blood circulation scattered silt, detumescence hemostasis, menstruction regulating and pain relieving, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle work(
Effect；For a lump in the abdomen causing distension and pain, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative.
Spina gleditsiae：Enter lung, Liver Channel, controls swollen ulcer drug, scrofula, sore rash stubborn dermatitis, pestilential wind；Modern anticancer pharmacological research shows
Spina gleditsiae has anticancer tumor-suppression activity.
Radix Glycyrrhizae：Enter spleen, stomach, lung channel, invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription；For swallowing
Larynx swelling and pain, ulcerative carbuncle swelling and pain, weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen four limbs contraction, can abirritant
It is object toxicity, strong.
Radix Angelicae Sinensis：Return liver, the heart, the spleen channel；It enriches blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation；Cure mainly all cards of the deficiency of blood, irregular menstruation,
Amenorrhea, dysmenorrhoea, abdominal mass knot are poly-, uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness, intestines are dry and shit is difficult, ulcer sores.
Radix paeoniae rubra：Return liver warp has the effect of clearing heat and cooling blood, promoting blood circulation, analgesic；For thermal man's ying blood, febrile virulent maculae, hot eyes
Swelling and pain, liver-depressed hypochondrium pain, closed dysmenorrhea, addiction lump in the abdomen abdominal pain, carbuncle swells sore.
Radix bupleuri：Return liver, gallbladder channel, tool soothing liver-gallbladder dredge that gas solution is strongly fragrant, dissipates effect of fire, cure mainly stagnation of QI due to depression of the liver, sternal rib pain,
Uterus falls off, irregular menstruation.
Radix Curcumae：Return liver, the heart, lung channel, can promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, normalizing gallbladder to cure jaundice.
The present invention treats the Chinese medicine of the proliferation of mammary gland, advantages and beneficial effects：Can dispersing liver and promoting blood circulation, softening and resolving hard mass, detumescence stop
Bitterly；It is depressed for liver depression, the proliferation of mammary gland caused by qi depression to blood stasis, newborn core tubercle, distending pain；Its prescription is scientific and reasonable, and compatibility is only
It arrives, it is significant in efficacy；There is treating both manifestation and root cause of disease, have no toxic side effect, is quick, is the treatment proliferation of mammary gland, breast the features such as difficulty in relapse after healing
The good Chinese medicine of core tubercle；Its production method is simple, at low cost, is suitble to private clinic evolution to cure the disease, also is adapted for situation of all-level hospitals system
Agent and pharmaceutical factory's production.
The clinical therapeutic efficacy of the present invention further explained below：
Clinical observation of the present invention through more than two decades selects proliferation of mammary gland patient 100；Medication counts after 60 days, clinical
43 are cured, accounts for 43%；Effective 54, account for 54%；It is verified through X-ray and ultrasound, 1 week or so significant effect of taking medicine, after one month
Symptom disappears or mitigates；Total effective rate is 97%, and uneasy to recur.
Its model case is as follows：
Case 1, Huan Zhenv, 33 years old, peasant, on April 10th, 2012 went to a doctor.Bilateral lump in breast pain more than 3 months, with the moon
It is aggravated through the period, bilateral breast hyperplasia is diagnosed as through mammary diagnosis instrument and ultrasound diagnosis.Physical examination：Left breast inner lower quadrant is accessible
Multiple lesser tubercles, the tubercle of accessible 2cm × 2cm of right breast outer quadrant or so；Quality is flexible, surface is smooth, mobility is big, with
Surrounding skin adhesion, boundary is clear, has tenderness to feel, and two axillary lymph knot not enlargements are dark with Hypomenorrhea, color, premenstrual 1 week breast
Room pain aggravates.The Chinese medicine for taking the present invention, after 1 month, lump is obviously reduced, pain relief；Continue after taking 2 months, lump disappears
It dissipates, pain disappearance, follow-up is not recurred for 1 year.
Case 2, Huan Zhenv, 43 years old, peasant, on April 12nd, 2012 went to a doctor.Unilateral lump in breast pain more than 6 months, through B
It is super to check as the unilateral proliferation of mammary gland.Physical examination：The accessible multiple lesser tubercles of left breast inner lower quadrant, the accessible 3cm × 2cm of outer quadrant
The tubercle of left and right；Quality is flexible, surface is smooth, mobility is big, clear with surrounding skin adhesion, boundary；There is tenderness to feel, oxter leaching
Not enlargement is fawned on, dark with Hypomenorrhea, color, premenstrual 1 week breast pain aggravates.The Chinese medicine for taking the present invention after 1 month, swells
Block is obviously reduced, pain relief；Continue after taking 2 months, lump dissipates, pain disappears, and follow-up is not recurred for 1 year.
Case 3, Huan Zhenv, 32 years old, cadre, on April 15th, 2012 went to a doctor.Unilateral lump in breast pain more than 2 months, through B
It is super to check as the unilateral proliferation of mammary gland, breast tubercle.The Chinese medicine for taking the present invention, after 1 week, pain relief；Continue after taking 1 month, knot
Section dissipates, pain disappears, and follow-up is not recurred for 1 year.
Case 4, Huan Zhenv, 37 years old, worker, on April 17th, 2012 went to a doctor.Bilateral lump in breast pain more than 1 month, with the moon
It is aggravated through the period, ultrasound diagnosis is bilateral breast hyperplasia.The Chinese medicine of the present invention is taken, after taking medicine 1 week, pain relief is continuous to take 1
After a month, lump dissipates, pain disappears, and follow-up is not recurred for 1 year.
Case 5, Huan Zhenv, 27 years old, waiter, on May 17th, 2012 went to a doctor.Bilateral breast pain more than 1 month, with menstruation
Period and aggravate；Ultrasound diagnosis is bilateral breast hyperplasia.The Chinese medicine of the present invention is taken, after taking medicine 1 week, pain relief is continuous to take 1
After month, pain disappears, and follow-up is not recurred for 1 year.
Specific implementation mode
In order to make those skilled in the art be better understood from the present invention, the present invention is made with reference to embodiment further
Explanation.
Embodiment 1
Take following weight raw medicinal material：50 grams of Prunella vulgaris, 250 grams of safflower, 150 grams of Radix Salviae Miltiorrhizae, 50 grams of spina gleditsiae, Radix Glycyrrhizae 200
Gram, 150 grams of Radix Angelicae Sinensis, 50 grams of radix paeoniae rubra, 50 grams of radix bupleuri, 200 grams of Radix Curcumae.
Above-mentioned component is pressed《Pharmacy》In medicine pill technique prepare pelletization, through drying, sterilizing, obtain 10/2 grams of sheet
The Chinese medicine of the invention treatment proliferation of mammary gland.
Usage and dosage：Oral one time 25-30,2 times a day, one after each meal；Points for attention：Menstrual period is discontinued.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and above-mentioned component is pressed《Pharmacy》Middle known method can produce any one
Kind《Pharmacy》In described peroral dosage form.
Embodiment 2
Take following weight raw medicinal material：150 grams of Prunella vulgaris, 150 grams of safflower, 250 grams of Radix Salviae Miltiorrhizae, 150 grams of spina gleditsiae, Radix Glycyrrhizae
100 grams, 50 grams of Radix Angelicae Sinensis, 150 grams of radix paeoniae rubra, 150 grams of radix bupleuri, 100 grams of Radix Curcumae.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and the preparation process of medicine pill, usage and dosage are same as Example 1.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and above-mentioned component is pressed《Pharmacy》Middle known method can produce any one
Kind《Pharmacy》In described peroral dosage form.
Embodiment 3
Take following weight raw medicinal material：100 grams of Prunella vulgaris, 200 grams of safflower, 200 grams of Radix Salviae Miltiorrhizae, 100 grams of spina gleditsiae, Radix Glycyrrhizae
150 grams, 100 grams of Radix Angelicae Sinensis, 100 grams of radix paeoniae rubra, 100 grams of radix bupleuri, 150 grams of Radix Curcumae.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and the preparation process of medicine pill, usage and dosage are same as Example 1.
The present invention treats the Chinese medicine of the proliferation of mammary gland, and above-mentioned component is pressed《Pharmacy》Middle known method can produce any one
Kind《Pharmacy》In described peroral dosage form.
Claims (4)
1. a kind of Chinese medicine for treating the proliferation of mammary gland, it is characterised in that be made by following raw material medicinal material formulas：Prunella vulgaris 5~
15 parts, 15~25 parts of safflower, 15~25 parts of Radix Salviae Miltiorrhizae, 5~15 parts of spina gleditsiae, 10~20 parts of Radix Glycyrrhizae, 5~15 parts of Radix Angelicae Sinensis, radix paeoniae rubra 5~
15 parts, 5~15 parts of radix bupleuri, 10~20 parts of Radix Curcumae.
2. the Chinese medicine of the treatment proliferation of mammary gland according to claim 1, it is characterised in that the parts by weight of raw medicinal material formula are：
10 parts of Prunella vulgaris, 20 parts of safflower, 20 parts of Radix Salviae Miltiorrhizae, 10 parts of spina gleditsiae, 15 parts of Radix Glycyrrhizae, 10 parts of Radix Angelicae Sinensis, 10 parts of radix paeoniae rubra, 10 parts of radix bupleuri,
15 parts of Radix Curcumae.
3. the Chinese medicine of the treatment proliferation of mammary gland according to claim 1 or 2, it is characterised in that：The dosage form of the Chinese medicine is ball
Agent.
4. the Chinese medicine of the treatment proliferation of mammary gland according to claim 1 or 2, it is characterised in that：The dosage form of the Chinese medicine is medicine
Described any type peroral dosage form in agent.
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107213426B (en) * | 2017-06-14 | 2021-03-26 | 黑龙江天龙药业有限公司 | Chinese patent medicine for treating mammary gland diseases and preparation method thereof |
| CN111991537A (en) * | 2020-09-24 | 2020-11-27 | 深圳市纯原上品生物科技有限公司 | A Chinese medicinal composition for treating female hyperplasia of mammary glands and preventing canceration, and its preparation method |
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| CN1539432A (en) * | 2003-04-24 | 2004-10-27 | 刘连华 | Granule of intermal dissolution for breast nodule |
| CN101524452A (en) * | 2008-03-06 | 2009-09-09 | 北京中科仁和科技有限公司 | Chinese medicinal composition for treating hyperplasia of mammary glands and preparation method thereof |
| CN102240382A (en) * | 2011-07-12 | 2011-11-16 | 张俊波 | Traditional Chinese medicine for treating mammary gland hyperplasia |
| CN104162105A (en) * | 2014-07-23 | 2014-11-26 | 贺珍 | Medicine for treating acute mastitis |
| CN104258272A (en) * | 2014-09-09 | 2015-01-07 | 张育海 | Traditional Chinese medicine for treating nodules of breast |
-
2015
- 2015-06-03 CN CN201510325133.0A patent/CN104958693B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539432A (en) * | 2003-04-24 | 2004-10-27 | 刘连华 | Granule of intermal dissolution for breast nodule |
| CN101524452A (en) * | 2008-03-06 | 2009-09-09 | 北京中科仁和科技有限公司 | Chinese medicinal composition for treating hyperplasia of mammary glands and preparation method thereof |
| CN102240382A (en) * | 2011-07-12 | 2011-11-16 | 张俊波 | Traditional Chinese medicine for treating mammary gland hyperplasia |
| CN104162105A (en) * | 2014-07-23 | 2014-11-26 | 贺珍 | Medicine for treating acute mastitis |
| CN104258272A (en) * | 2014-09-09 | 2015-01-07 | 张育海 | Traditional Chinese medicine for treating nodules of breast |
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