CN104940547A - Traditional Chinese medicine combination for treating hemorrhoid and preparation technology therefor - Google Patents
Traditional Chinese medicine combination for treating hemorrhoid and preparation technology therefor Download PDFInfo
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- CN104940547A CN104940547A CN201510300499.2A CN201510300499A CN104940547A CN 104940547 A CN104940547 A CN 104940547A CN 201510300499 A CN201510300499 A CN 201510300499A CN 104940547 A CN104940547 A CN 104940547A
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Abstract
The present invention relates to a traditional Chinese medicine combination for treating hemorrhoid and the preparation technology therefor. The traditional Chinese medicine combination belongs to the field of pharmaceutical manufacturing technology and is mainly characterized by comprising 150-200 parts of ramulus mori, 150-200 parts of willow branches and leaves, 150-200 parts of pagoda tree branches and leaves, 50 parts of Chinese honey locust thorns, 15 parts of Chinese prickly ash, 5 parts of Artemisia argyi, 10 parts of garlic flakes, 50 parts of edible salt and 150 parts of edible vinegar. The above raw materials are air-dried and decocted in water to prepare the traditional Chinese medicine combination. The traditional Chinese medicine combination has fewer compositions and the medicinal materials of the traditional Chinese medicine combination are reasonably collocated. Meanwhile, the traditional Chinese medicine combination is simple in preparation process. The results of clinical tests show that, the traditional Chinese medicine combination has the effects of anti-inflammation, relieving pain, relieving itching, promoting blood circulation and removing blood stasis. During the diseased period and the recovery period of hemorrhoid, the results of human trials show that, the traditional Chinese medicine combination is better in treatment effect on swelling and itching caused by hemorrhoid, and the cure rate of the traditional Chinese medicine combination is up to over 80 %. The effective rate of the traditional Chinese medicine combination is up to over 90 %. Meanwhile, the traditional Chinese medicine combination is very small in toxic and side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine and preparation technology thereof, a kind of Chinese medicine composition and preparation technology thereof treating hemorrhoid of specific description, belongs to medicine manufacture technology field.
Background technology
Hemorrhoid are a kind of commonly encountered diseases, frequently-occurring disease, and China is among the people have saying of " ten people nine hemorrhoid ", and visible this kind of disease is very general, and sickness rate is very high.Along with the development of modern social economy, the increase of mental work crowd, the time of people's physical training reduces relatively, fat, and constipation person increases, the increase of sitting station person for a long time, especially the increasing of cybraian, and hemorrhoid sickness rate is also rising year by year.
At present, treatment hemorrhoid mainly adopt Western medicine injection treatment and excision two kinds of methods both at home and abroad.By the method for infusion of medicine blood stasis internal therapy hemorrhoid.Clinical normally used injection mainly contains sclerosis atrophy agent and the downright bad agents for defoliating two kinds of withered hemorrhoid.Sclerosing agent is applicable to internal hemorrhoid in each in period, more conventional clinically at present, but after drug-induced aseptic inflammation loss for reaction, fibrosis is shunk and squeezing action relaxes gradually, and blood stasis easily recurs.As injection site is excessively shallow, mucosa is then easily caused to fester mucosa abscess, cross and deeply easily cause an aromatic plant metioned in ancient books layer tissue to harden, dose is excessive, can cause downright bad massive hemorrhage, and medicinal liquid infiltrates can to cause that anus has an intense pain outside tooth trace, edema or thrombosis, excessive postoperative gangrenosum acne massive hemorrhage or the infection and necrosis face of often can causing of downright bad agent consumption forms ulcer, particularly tissue necrosis or infection widely, not only treatment time is long, and cicatricial contraction can cause anal stenosis sequela.The red withered hemorrhoid of painting of Traditional Chinese Medicine, necrotizing nail therapy for hemorrhoid, because toxic and side effects reaction is large, patient is painful comparatively greatly, the course for the treatment of is longer, present clinical little employing, take excision hemorrhoid in addition, adopt the method that Western medicine and Chinese medicine carry out disinfection, but treatment cost of performing an operation is high, postoperatively affect work, and it is large to have pain, postoperative easy recurrence, can not treating both the principal and secondary aspects of a disease, Western medicine generally takes effect than comparatively fast, but is difficult to eliminate focus, and can not effect a radical cure, long-term prescription cost is high, has side effect to health.Chinese medicine is compared with performing an operation and Western medicine in treatment and prevention piles, and have unique effect, it is except treatment cost is cheap, and outstanding is that its toxic and side effects is very little, not easily recurs after healing.The maximum feature for the treatment of by Chinese herbs piles is effected a permanent cure exactly, is effect hemorrhoid to treating both the principal and secondary aspects of a disease, so should select treatment by Chinese herbs hemorrhoid effectiveness comparison.
Therefore, the present invention provides a kind of at this and adopts pure Chinese medicine to treat hemorrhoid, and preparation technology is simple, a kind of Chinese medicine preparation that cost is relatively cheap.
Summary of the invention
Object of the present invention is exactly high in order to solve excision piles cost, has pain, postoperatively affects work, postoperative easy recurrence, can not the problem for the treatment of both the principal and secondary aspects of a disease.Western medicine is difficult to thoroughly eliminate focus, and can not fundamentally treat, and long-term prescription cost is high, to health toxic side effect, thus provides a kind of new technical scheme.
For achieving the above object, the present invention is by realizing with under type:
Treat a Chinese medicine composition for hemorrhoid, it is the decoction be made up according to weight of following raw materials according:
Folium et Ramulus Mori 150 ~ 200 parts, 150 ~ 200 parts, Ramulus Salicis Babylonicae leaf, 150 ~ 200 parts, Rumalus sophorae leaf,
Fructus Gleditsia acupuncture 50 parts, 15 parts, Pericarpium Zanthoxyli, Folium Artemisiae Argyi 5 parts, garlic clove 10 parts, Sal 50 parts,
Vinegar 150 parts.
Treat a Chinese medicine composition for hemorrhoid, it is the decoction be made up according to weight of following raw materials according:
Treat a preparation technology for the Chinese medicine composition of hemorrhoid, it is prepared into decoction by following method and step:
(1) air-dry process: above nine taste raw materials, Folium et Ramulus Mori, Ramulus Salicis Babylonicae leaf and Rumalus sophorae leaf, be cut into the long brachyplast of 1cm and Folium Artemisiae Argyi, garlic clove locate natural air drying in shady and cool drying, and obtain mixed material, for subsequent use, Fructus Gleditsia acupuncture is ground into 1-3 centimetre, for subsequent use, and Pericarpium Zanthoxyli is for subsequent use;
(2) decocting in water extracts: the mixed material after air-dry process, Fructus Gleditsia acupuncture and Pericarpium Zanthoxyli put into room temperature snow water or spring water, then heat when water temperature is at 35 DEG C-40 DEG C with Sal and vinegar, first time amount of water be each medicament mixed together gross weight 4-5 doubly, soak by water 2 times, decocting time 90 minutes, second time amount of water be each medicament mixed together gross weight 3-4 doubly, decocting time 70-90 minute, twice decoction liquor merges, filtration residue leaves and takes medicinal liquid twice, precipitate 7-8 hour naturally cool after get clear liquid medicine and load in bottle and get final product, bottled specification 100ml.
The present invention is advantageously: Chinese crude drug prescription is few, easy to use, only has nine taste Chinese medicines, and Pharmaceutical formulations is reasonable, has antiinflammatory, pain relieving, antipruritic, the effect of blood circulation promoting and blood stasis dispelling.Can be used for swelling and ache antipruritic period of disease and convalescent period of mixed hemorrhoids inflammation, have certain therapeutical effect to acne.Shown the swelling and pain of anus caused piles by human trial, pruritus, feels restless, and affect work etc. and have significant therapeutic effect, and toxic and side effects is very little.Between period of disease, therapeutic effect is best, and this prescription is mainly adapted to mixed hemorrhoids in hemorrhoid, the period of disease of mixed hemorrhoid and convalescent patient.
Detailed description of the invention
Embodiment one: a kind of Chinese medicine composition for the treatment of hemorrhoid, it is the external decoction be made up according to weight in grams (g) of following raw materials according:
Folium et Ramulus Mori 150g, Ramulus Salicis Babylonicae leaf 150g, Rumalus sophorae leaf 150g, Fructus Gleditsia acupuncture 50g, Pericarpium Zanthoxyli 15g, Folium Artemisiae Argyi 5g, garlic clove 10g, Sal 50g, vinegar 150g.
The snow water that winter collects is as decoction liquor.
Treat a preparation technology for the Chinese medicine composition of hemorrhoid, it is prepared from decoction by following method and step:
(1) the air-dry process of cutting: above nine taste raw material of Chinese medicine, adopts raw Folium et Ramulus Mori, Ramulus Salicis Babylonicae leaf, Rumalus sophorae leaf then, and the brachyplast and Folium Artemisiae Argyi, the garlic clove that are cut into 1cm length locate natural air drying in shady and cool drying, obtain mixed material, for subsequent use, Fructus Gleditsia acupuncture is ground into 2 centimetres, for subsequent use, Pericarpium Zanthoxyli is for subsequent use.
(2) decocting in water extracts: decoction liquor is snow water, puts into medicine at normal temperatures, soaks 30 minutes, heating when water temperature is at 35 DEG C-40 DEG C salt adding, with vinegar, snow water amount be each medicament mixed together gross weight 4-5 doubly, snow water decocts 2 times, 90 minutes for the first time; Second time snow water amount be each medicament mixed together gross weight 3-4 doubly, second time decocting time 70 minutes, decoction liquor merges, and filtration residue leaves and takes water liquid for twice, gets in supernatant loading bottle and get final product, bottled specification 100ml after 7-8 hour medicinal liquid is naturally cool.
Embodiment two:
Each raw material former gram (g) is by weight got:
Folium et Ramulus Mori 200g, Ramulus Salicis Babylonicae leaf 200g, Rumalus sophorae leaf 200g, Fructus Gleditsia acupuncture 50g, Pericarpium Zanthoxyli 15g, Folium Artemisiae Argyi 5g, garlic clove 10g, Sal 50g, vinegar 150g.
Spring water is as decoction liquor.
Be prepared into decoction method and step with embodiment one.
Using method: external, 2-3 time on the one, dips in medicine with medical cotton ball and repeatedly wipes and rub affected part 10-15 minute, a drug amount 30ml.Severe patient is wiped and is rubbed 30 minutes, and dose doubles, and avoids pungent and excitant food during medication, can not drink.
Name of product of the present invention is called " three Hemorrhoid preparations ", three be Folium et Ramulus Mori in raw material of Chinese medicine, middle word in the title of Ramulus Salicis Babylonicae leaf and Rumalus sophorae leaf and gaining the name.
The dosage form made of Chinese medicine Folium et Ramulus Mori, Ramulus Salicis Babylonicae leaf and Rumalus sophorae leaf has the effect of antiinflammatory, pain relieving, antipruritic and blood circulation promoting and blood stasis dispelling in prescription to hemorrhoid.
In the present invention, full prescription is made up of Folium et Ramulus Mori, Rumalus sophorae leaf, Ramulus Salicis Babylonicae leaf, Fructus Gleditsia acupuncture, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, garlic clove, Sal, vinegar nine taste Chinese medicine.In side Folium et Ramulus Mori have dispel the wind, active, blood stasis dispelling, dehumidifying, heat clearing away and removing heat from blood expelling summer-heat effect, Folium et Ramulus Mori joins Folium Mori, and dredging is had both, dispelling wind and removing obstruction in the collateral, and pain relieving benefit is evident.Rumalus sophorae leaf has the function of removing heat from blood antiinflammatory, dissipating blood stasis hemostasis, heat clearing and damp drying.Ramulus Salicis Babylonicae leaf has the function of pain relieving, detumescence, clearing away heat and cooling blood and removing toxic substances.Folium et Ramulus Mori, Rumalus sophorae leaf, Ramulus Salicis Babylonicae leaf branch leaf share to be combined as a whole by force by force has the effect of detumescence, pain relieving, blood circulation promoting and blood stasis dispelling, is control hemorrhoid material combination unique distinction.Fructus Gleditsia acupuncture containing flavonoid glycoside, phenols, aminoacid, can have draw out pus by applying a plaster to the affected part, antiinflammatory, detumescence and evacuation of pus effect.Folium Artemisiae Argyi contains tannin and pyrite alcohol, and in pharmacology, Folium Artemisiae Argyi has antibacterial, antiviral, antiallergic, hemostasis, detumescence and anticoagulant effect.Pericarpium Zanthoxyli wets, good antimicrobial effect.Garlic clove proves to have powerful anti-bacteria and the effect of fungus through test, and it can kill Bacillus typhi in 5 minutes, also had antipruritic effect.Four taste Chinese Medicine and Clavicular detumescences, antipruritic, hemostasis, effect doubles, and coordinates Folium et Ramulus Mori, Rumalus sophorae leaf and Ramulus Salicis Babylonicae leaf, and can strengthen detumescence, pain relieving, the effect of drawing out pus by applying a plaster to the affected part, all the other each taste medicines are held concurrently as assistant makes it use, and vinegar has relieving distension, antipruritic effect.Pericarpium Zanthoxyli has seasoning parasite killing and antipruritic special role.Folium et Ramulus Mori in this prescription, Rumalus sophorae leaf, Ramulus Salicis Babylonicae leaf in conjunction with four taste Chinese medicines, be applicable to piles swollen, bitterly, the patient that itches, comprise the patient of internal hemorrhoid and external hemorrhoid.
Clinical trial:
Carry out human trial set forth the present invention further compared with prior art at the therapeutic effect that treatment hemorrhoid have below by way of old people, middle age, adolescence, and toxic and side effects is very little.
(1) acute toxic reaction that the medicine that observation the present invention produces produces after human trial and patient form situation;
(2) experimenter and test material:
A, old people, middle age, adolescence's hemorrhoid patients;
B, medicine, " three Hemorrhoid preparations " that the present invention produces is that pure Chinese crude drug is processed into;
(3) test method and result.
Piles patient medication every day 2-3 time, each wiping rubs 10-15 minute, and severe patient is wiped and rubbed 30 minutes, each dosage 30m1, and severe patient doubles to use.Will medication on time, repeatedly wipe and rub, just can play effect for the treatment of both the principal and secondary aspects of a disease.
Clinical case is added up:
From 2010 to 2015 5 years, utilize the present invention to be that upper over one hundred routine patient treats, existing random sampling 20 case histories are added up, and statistical result sees the following form.
These are per capita for using the patient that other medicines are invalid.At minimum 20 years old of age, older the is old man of 75 years old, having in this its patient is much the patient of recurring again after second operation.Brain worker and physical labourer is had in patient.
To this, We conducted test, experimenter's grouping is carried out, and enters group and each group of situation data: experimental group number 20 people, its middle-aged and elderly people 3 people, middle age 11 people, adolescence 6 people, and after treatment, result is as follows:
Clinical trial effective percentage statistical table
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate |
| Young | 6 | 1 | 4 | 1 | 83.30％ |
| Middle age | 11 | 2 | 8 | 1 | 90.90％ |
| Old | 3 | 1 | 3 | 0 | 100％ |
Shown by result of the test: the present invention, in the hemorrhoid for the treatment of old people, middle age and adolescence, has antiinflammatory, pain relieving, antipruritic, the effect of blood circulation promoting and blood stasis dispelling.The misery of patient can be alleviated fast, can be used for period of disease and the convalescent period of hemorrhoid, by human trial and visit and investigate prove piles is caused swell and ache, pruritus, have good therapeutical effect, cure rate reaches more than 80%, and effective percentage reaches more than 90%, and toxic and side effects is very little, relapse rate is very low.
(4) brief summary
" three Hemorrhoid preparations " that the present invention produces to have acute toxicity extremely low, and be external used medicine, the larger therapeutic effect of dosage is better.
The old people that routine is carried out " three Hemorrhoid preparations ", middle age, in clinical treatment hemorrhoid, the experiment proved that: the continuous use symptom of 2 days alleviates, successful, and the symptom of continuous use 7-15 days is eliminated, better effects if.Adolescence due to metabolism vigorous, result of use is better than old people and middle age.If but adolescence because of the daily schedule irregular, affect by living habit and working environment, curative effect can be weaker.Such as the food of adolescence's practical pungent stimulation during medication, is on the drink, the staff of frequent sitting before computer, and therapeutic effect is again inferior to old people and middle age.Show according to clinical trial results, acute toxic reaction and allergic conditions is not found after old people, middle age, adolescence's medication, frequent use " three Hemorrhoid preparations " can make that anus is salubrious, pneumonedema, bitterly, not do not itch, and can effectively treat and prevent the generation of piles.
Claims (3)
1. treat a Chinese medicine composition for hemorrhoid, it is characterized in that the decoction be made up according to weight of following raw materials according:
Folium et Ramulus Mori 150 ~ 200 parts, 150 ~ 200 parts, Ramulus Salicis Babylonicae leaf, 150 ~ 200 parts, Rumalus sophorae leaf,
Fructus Gleditsia acupuncture 50 parts, 15 parts, Pericarpium Zanthoxyli, Folium Artemisiae Argyi 5 parts, garlic clove 10 parts, Sal 50 parts,
Vinegar 150 parts.
2. a kind of Chinese medicine composition for the treatment of hemorrhoid according to claim 1, is characterized in that the decoction be made up according to weight of following raw materials according:
Folium et Ramulus Mori 150 parts, 150 parts, Ramulus Salicis Babylonicae leaf, 150 parts, Rumalus sophorae leaf, Fructus Gleditsia acupuncture 50 parts,
15 parts, Pericarpium Zanthoxyli, Folium Artemisiae Argyi 5 parts, garlic clove 10 parts, Sal 50 parts,
Vinegar 150 parts.
3. treat a preparation technology for the Chinese medicine composition of hemorrhoid, it is characterized in that being prepared into decoction by following method and step:
(1) air-dry process: above nine taste raw materials, Folium et Ramulus Mori, Ramulus Salicis Babylonicae leaf and Rumalus sophorae leaf, be cut into the long brachyplast of 1cm and Folium Artemisiae Argyi, garlic clove locate natural air drying in shady and cool drying, and obtain mixed material, for subsequent use, Fructus Gleditsia acupuncture is ground into 1-3 centimetre, for subsequent use, and Pericarpium Zanthoxyli is for subsequent use;
(2) decocting in water extracts: the mixed material after air-dry process, Fructus Gleditsia acupuncture and Pericarpium Zanthoxyli put into room temperature snow water or spring water, then heat when water temperature is at 35 DEG C-40 DEG C with Sal and vinegar, first time amount of water be each medicament mixed together gross weight 4-5 doubly, soak by water 2 times, decocting time 90 minutes, second time amount of water be each medicament mixed together gross weight 3-4 doubly, decocting time 70-90 minute, twice decoction liquor merges, filtration residue leaves and takes medicinal liquid twice, precipitate 7-8 hour naturally cool after get clear liquid medicine and load in bottle and get final product, bottled specification 100ml.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535209A (en) * | 2016-01-04 | 2016-05-04 | 马林 | External washing traditional Chinese medicine composition for treating haemorrhoids |
| CN108452197A (en) * | 2018-04-12 | 2018-08-28 | 姚德江 | A kind of prescription and method for treating hemorrhoid |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1353998A (en) * | 2000-11-21 | 2002-06-19 | 亓树智 | Chinese medicine preparation for curing hemorrhoid |
| CN101040947A (en) * | 2007-04-18 | 2007-09-26 | 李荣年 | Chinese traditional medicine for treating eczema and other dermatosis |
| CN101653474A (en) * | 2009-09-17 | 2010-02-24 | 刘承彪 | Medicine for treating hemorrhoid and its preparing process |
-
2015
- 2015-05-29 CN CN201510300499.2A patent/CN104940547B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1353998A (en) * | 2000-11-21 | 2002-06-19 | 亓树智 | Chinese medicine preparation for curing hemorrhoid |
| CN101040947A (en) * | 2007-04-18 | 2007-09-26 | 李荣年 | Chinese traditional medicine for treating eczema and other dermatosis |
| CN101653474A (en) * | 2009-09-17 | 2010-02-24 | 刘承彪 | Medicine for treating hemorrhoid and its preparing process |
Non-Patent Citations (2)
| Title |
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| 山东中医学院中药方剂教研室: "《中药方剂学》", 31 December 1976 * |
| 田建利等: "《痔疮发飙，你怎么办？—略释痔病防治130惑》", 30 April 2015 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105535209A (en) * | 2016-01-04 | 2016-05-04 | 马林 | External washing traditional Chinese medicine composition for treating haemorrhoids |
| CN108452197A (en) * | 2018-04-12 | 2018-08-28 | 姚德江 | A kind of prescription and method for treating hemorrhoid |
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