CN104940539A

CN104940539A - Traditional Chinese medicine preparation for treating peripheral facial paralysis

Info

Publication number: CN104940539A
Application number: CN201510337912.2A
Authority: CN
Inventors: 郭仕峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-06-10
Filing date: 2015-06-10
Publication date: 2015-09-30

Abstract

The invention discloses a traditional Chinese medicine preparation for treating peripheral facial paralysis. The traditional Chinese medicine considers that the wry mouth is caused by the fact that wind pathogens enter midface meridians and collaterals due to insufficient anti-pathogenic energy, weakness of meridian and collaterals, and defensive qi instability, or inherent wind phlegm and blood stasis in a body and blocking of facial meridians and collaterals. Therefore, traditional Chinese medicines including smilax riparia, roots of gynura bicolor, cyperus difformis, herb of selaginella davidii, roots of berchemia floribunda, sopubia trifida, aralia elata, crotalaria ferruginea, herb of tree clubmoss, chonemorpha megacalyx and mucuna sempervirens are decocted into decoction with water. A clinical test result shows that the total effective rate is 92.73% and is obviously superior to 73.33% of a control group, and curative effect is obvious.

Description

A kind of Chinese medicine preparation for the treatment of peripheral facial paralysis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine preparation for the treatment of peripheral facial paralysis.

Background technology

Peripheral facial paralysis, also known as facial neuritis, is one of common clinical, and its cause of disease still imperfectly understands so far.Being commonly considered as being caused caused by the local vasospasm of trophic nerve, ischemia, edema by a variety of causes, is usually the infringement of nervus facialis near-end.Although modern medicine thinks that the definite cause of disease of peripheral facial paralysis is not yet completely clear, but the pathological change in each stage is affirmative, with the blood vessel generation spasm of local trophic nerve, cause nervus facialis ischemia, edema, for the pathological change that it is main in early days, neural myelin or axonal degeneration in stylomastoid foramen and facial canal can be had simultaneously.Peripheral facial paralysis is higher in the prevalence of China, and any age all can fall ill, if treatment not in time or improper, often leaves certain sequela, and brings very large psychological burden to patient.

From clinical observation, although acute stage, nervus facialis was in the acute inflammation edema stage, nervus facialis is also in intermittent condition simultaneously, if now give the optimal stimulation that very weak, can muscle fibers contract be strengthened, accelerate the blood circulation of local, increase metabolism, inflammatory exudate can be made to absorb as soon as possible, thus improve injured nervus facialis, promote injured nerve recovery.For this reason, applicant, in treatment practice for many years, adopts Acupuncture treatment by Chinese herbs, achieves good curative effect.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of peripheral facial paralysis.Chinese medicine is thought, mouth is out-of-the-way is by positive QI-insufficiency, and venation is hollow, weakened defensive QI, and ailment said due to cold or exposure is taken advantage of a weak point septum reset meridians, or have in wind-phlegm blood stasis and accumulate, facial passages through which vital energy circulates retardance and falling ill.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment peripheral facial paralysis is made up of the Chinese medicine of following weight portion: Radix et Rhizoma Smilacis Ripariae 8-12 part, Radix Gynurae bicoloris 40-50 part, Herba Cyperi Difformis 30-40 part, Herba Selaginellae Davidii 3-9 part, Radix berchemiae floribundae 10-20 part, Herba sopubiae Trifidae 6-8 part, Cortex Araliae Elatae Radicis 15-25 part, Herba Crotalariae Ferrugineae 15-25 part, Herba Lycopodii Obscuri 10-15 part, Caulis Chonemorphae Megacalycis 8-12 part, Radix Seu Caulis Mucunae Sempervirentis 10-20 part.

Preferably, Radix et Rhizoma Smilacis Ripariae 10 parts, Radix Gynurae bicoloris 45 parts, Herba Cyperi Difformis 35 parts, Herba Selaginellae Davidii 6 parts, Radix berchemiae floribundae 15 parts, Herba sopubiae Trifidae 7 parts, Cortex Araliae Elatae Radicis 20 parts, Herba Crotalariae Ferrugineae 20 parts, Herba Lycopodii Obscuri 12 parts, Caulis Chonemorphae Megacalycis 10 parts, Radix Seu Caulis Mucunae Sempervirentis 15 parts.

Above-mentioned Chinese medicine decocting is made decoction by preparation method.

Fang Zhong: Radix et Rhizoma Smilacis Ripariae QI invigorating, relaxing muscles and tendons and activating QI and blood in the collateral, to invigorate blood circulation; Radix Gynurae bicoloris is invigorated blood circulation, circulation of qi promoting; Herba Cyperi Difformis is treating stranguria, diuresis, circulation of qi promoting, invigorate blood circulation; Herba Selaginellae Davidii relaxing muscles and tendons and activating QI and blood in the collateral; Radix berchemiae floribundae dredge the meridian passage, invigorating the spleen and benefiting QI, cold-damp of dispeling the wind; Herba sopubiae Trifidae relaxing muscles and tendons and activating QI and blood in the collateral, pain relieving, the kidney warming; Cortex Araliae Elatae Radicis invigorating QI and tranquilization, essence strengthening and the kidney invigorating, Shufeng Huoluo; Herba Crotalariae Ferrugineae invigorating the spleen and replenishing QI, invigorating spleen for diuresis; Herba Lycopodii Obscuri QI invigorating is quenched the thirst; Caulis Chonemorphae Megacalycis is invigorated blood circulation, dredge the meridian passage, hemostasis, bone and muscle strengthening; Radix Seu Caulis Mucunae Sempervirentis is enriched blood promoting the circulation of blood, dredge the meridian passage.

Clinical data

1, physical data peripheral facial paralysis acute stage case is all from the court's department of acupuncture and moxibustion, and meet diagnostic criteria 85 routine patients are divided into matched group and treatment group at random by random table.Matched group 40 example, man 19 example, female 11 example; Treatment group 45 example, man 19 example, female 26 example.

2, the diagnosis of diagnostic criteria peripheral facial paralysis is formulated with reference to " clinical disease diagnosis is according to curing improvement standard ".

3, Therapeutic Method matched group patient carries out the shallow acupuncture of Ipsilateral face in acute stage (in 7d), acupoint selection: yang white, Zanzhu, cheek car, ShiShimonoseki, dicang, Yingxiang, connected valleys (offside).Coordinate oral vitamin B1 20mg, day 3 times; Vitamin B6 20mg, day 3 times; Use in prednisone limit morbidity 2w, 30mg, day 1 time, decoction being taken at a draught when morning 8, serve on 7d, within the 8th day, plays decrement 5mg every day, after reducing to 5mg, then with 2.5mg, day 1 time, continues and takes 3d drug withdrawal; Bendazol 20mg, day 3 times.Acyclovir 0.2g, day 3 times.Treatment group patient carries out the shallow acupuncture of Ipsilateral face in acute stage (in 7d), acupoint selection: yang white, Zanzhu, cheek car, ShiShimonoseki, dicang, Yingxiang, connected valleys (offside).And determine with card acupoint selection and the maneuver of reinforcing and reducing according to Syndrome Differentiation of Traditional Chinese Medicine, the next day 1 time, be for 6 times 1 course for the treatment of, rest 3d between the course for the treatment of.This Chinese medicine preparation prescription: take Radix et Rhizoma Smilacis Ripariae 10g, Radix Gynurae bicoloris 45g, Herba Cyperi Difformis 35g, Herba Selaginellae Davidii 6g, Radix berchemiae floribundae 15g, Herba sopubiae Trifidae 7g, Cortex Araliae Elatae Radicis 20g, Herba Crotalariae Ferrugineae 20g, Herba Lycopodii Obscuri 12g, Caulis Chonemorphae Megacalycis 10g, Radix Seu Caulis Mucunae Sempervirentis 15g, be decocted in water for oral dose, the next day 1 dose, points of 2 times clothes.

4, criterion of therapeutical effect is formulated with reference to " clinical disease diagnosis is according to curing improvement standard ".Cure: patient's facial nerve motor function recovers normal, Ipsilateral, strong side surface part muscle are symmetrical, and Ipsilateral catacleisis is complete, nasolabial fold almost symmetry, and bicker is without crooked; Effective: patient's facial nerve motor function major part is recovered, and Ipsilateral eyelid can close, and time static, facial appearance is normal, and nasolabial fold is slightly shallow, distortion of commissure when laughing at; Effective: patient's facial nerve motor function part is recovered; Invalid: Ipsilateral facial nerve motor function is without improvement.

5, therapeutic outcome two groups of total Clinical efficacy comparisons of patient: treatment group cures 31 examples, effective 11 examples, effective 9 examples, invalid 4 examples, total effective rate is 92.73%; Matched group cures 12 examples, effective 5 examples, effective 5 examples, and invalid 8 examples, total effective rate is 73.33%.Two groups of total effective rates compare significant difference (P < 0.05).Treatment group Mean treatment duration is (20.6 ± 3.8) d, and matched group is (23.2 ± 4.3) d, and two groups are compared and have significant difference (P < 0.01).

Detailed description of the invention

Embodiment one: take Radix et Rhizoma Smilacis Ripariae 10g, Radix Gynurae bicoloris 45g, Herba Cyperi Difformis 35g, Herba Selaginellae Davidii 6g, Radix berchemiae floribundae 15g, Herba sopubiae Trifidae 7g, Cortex Araliae Elatae Radicis 20g, Herba Crotalariae Ferrugineae 20g, Herba Lycopodii Obscuri 12g, Caulis Chonemorphae Megacalycis 10g, Radix Seu Caulis Mucunae Sempervirentis 15g, decocting makes Chinese medicine preparation.

Embodiment two: take Radix et Rhizoma Smilacis Ripariae 12g, Radix Gynurae bicoloris 50g, Herba Cyperi Difformis 40g, Herba Selaginellae Davidii 9g, Radix berchemiae floribundae 20g, Herba sopubiae Trifidae 8g, Cortex Araliae Elatae Radicis 25g, Herba Crotalariae Ferrugineae 25g, Herba Lycopodii Obscuri 15g, Caulis Chonemorphae Megacalycis 12g, Radix Seu Caulis Mucunae Sempervirentis 20g, decocting makes Chinese medicine preparation.

Embodiment three: take Radix et Rhizoma Smilacis Ripariae 8g, Radix Gynurae bicoloris 40g, Herba Cyperi Difformis 30g, Herba Selaginellae Davidii 3g, Radix berchemiae floribundae 10g, Herba sopubiae Trifidae 6g, Cortex Araliae Elatae Radicis 15g, Herba Crotalariae Ferrugineae 15g, Herba Lycopodii Obscuri 10g, Caulis Chonemorphae Megacalycis 8g, Radix Seu Caulis Mucunae Sempervirentis 10g, decocting makes Chinese medicine preparation.

Claims

1. treat a Chinese medicine preparation for peripheral facial paralysis, it is characterized in that Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Radix et Rhizoma Smilacis Ripariae 8-12 part, Radix Gynurae bicoloris 40-50 part, Herba Cyperi Difformis 30-40 part, Herba Selaginellae Davidii 3-9 part, Radix berchemiae floribundae 10-20 part, Herba sopubiae Trifidae 6-8 part, Cortex Araliae Elatae Radicis 15-25 part, Herba Crotalariae Ferrugineae 15-25 part, Herba Lycopodii Obscuri 10-15 part, Caulis Chonemorphae Megacalycis 8-12 part, Radix Seu Caulis Mucunae Sempervirentis 10-20 part.

2. a kind of Chinese medicine preparation for the treatment of peripheral facial paralysis as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Radix et Rhizoma Smilacis Ripariae 10 parts, Radix Gynurae bicoloris 45 parts, Herba Cyperi Difformis 35 parts, Herba Selaginellae Davidii 6 parts, Radix berchemiae floribundae 15 parts, Herba sopubiae Trifidae 7 parts, Cortex Araliae Elatae Radicis 20 parts, Herba Crotalariae Ferrugineae 20 parts, Herba Lycopodii Obscuri 12 parts, Caulis Chonemorphae Megacalycis 10 parts, Radix Seu Caulis Mucunae Sempervirentis 15 parts.