CN104937101B - 设计趋异的密码子优化大重复dna序列的方法 - Google Patents
设计趋异的密码子优化大重复dna序列的方法 Download PDFInfo
- Publication number
- CN104937101B CN104937101B CN201380047742.3A CN201380047742A CN104937101B CN 104937101 B CN104937101 B CN 104937101B CN 201380047742 A CN201380047742 A CN 201380047742A CN 104937101 B CN104937101 B CN 104937101B
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- CN
- China
- Prior art keywords
- nucleic acid
- polypeptide
- codon
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
- A01H6/20—Brassicaceae, e.g. canola, broccoli or rucola
- A01H6/202—Brassica napus [canola]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
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- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261672114P | 2012-07-16 | 2012-07-16 | |
| US61/672,114 | 2012-07-16 | ||
| PCT/US2013/050744 WO2014014950A1 (en) | 2012-07-16 | 2013-07-16 | Process for designing diverged, codon-optimized large repeated dna sequences |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104937101A CN104937101A (zh) | 2015-09-23 |
| CN104937101B true CN104937101B (zh) | 2018-03-02 |
Family
ID=49949215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380047742.3A Expired - Fee Related CN104937101B (zh) | 2012-07-16 | 2013-07-16 | 设计趋异的密码子优化大重复dna序列的方法 |
Country Status (16)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR091774A1 (es) | 2012-07-16 | 2015-02-25 | Dow Agrosciences Llc | Proceso para el diseño de las secuencias de adn repetidas, largas, divergentes de codones optimizados |
| CA2971589C (en) | 2014-12-18 | 2021-09-28 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US10724040B2 (en) | 2015-07-15 | 2020-07-28 | The Penn State Research Foundation | mRNA sequences to control co-translational folding of proteins |
| US10811539B2 (en) | 2016-05-16 | 2020-10-20 | Nanomedical Diagnostics, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| SG11202101140TA (en) * | 2018-08-09 | 2021-03-30 | Speedx Pty Ltd | Multiplex detection of nucleic acids |
| AU2021446660A1 (en) * | 2021-05-18 | 2023-11-30 | Fujitsu Limited | Information processing program, information processing method, and information processing apparatus |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6018030A (en) | 1986-11-04 | 2000-01-25 | Protein Polymer Technologies, Inc. | Peptides comprising repetitive units of amino acids and DNA sequences encoding the same |
| AU612340B2 (en) | 1986-11-04 | 1991-07-11 | Protein Polymers Technologies, Inc. | Construction of synthetic dna and its use in large polypeptide synthesis |
| US5830713A (en) | 1986-11-04 | 1998-11-03 | Protein Polymer Technologies, Inc. | Methods for preparing synthetic repetitive DNA |
| ES2335861T3 (es) * | 2000-09-08 | 2010-04-06 | Universitat Zurich | Grupos de proteinas repetitivas que comprenden modulos repetitivos. |
| WO2002079502A1 (en) * | 2001-03-28 | 2002-10-10 | The University Of Queensland | A method for nucleic acid sequence analysis |
| US7368629B2 (en) | 2004-02-04 | 2008-05-06 | Divergence, Inc. | Nucleic acids encoding anthelmintic agents and plants made therefrom |
| US20070100377A1 (en) * | 2005-10-28 | 2007-05-03 | Cyberonics, Inc. | Providing multiple signal modes for a medical device |
| US20070292918A1 (en) | 2006-05-30 | 2007-12-20 | Stelman Steven J | Codon optimization method |
| TR200906533A2 (tr) | 2009-08-25 | 2010-03-22 | Nnt Nanoteknoloji̇ Bor Ür.Ve Ser.Malz | Detonasyon teknolojisi ve argon rejimi ile üretilmiş nano yağlayıcı katkı maddesi bileşimi ve üretim prosesi. |
| TW201144442A (en) * | 2010-05-17 | 2011-12-16 | Dow Agrosciences Llc | Production of DHA and other LC-PUFAs in plants |
| AR091774A1 (es) | 2012-07-16 | 2015-02-25 | Dow Agrosciences Llc | Proceso para el diseño de las secuencias de adn repetidas, largas, divergentes de codones optimizados |
-
2013
- 2013-07-15 AR ARP130102519 patent/AR091774A1/es unknown
- 2013-07-16 CA CA2879199A patent/CA2879199C/en active Active
- 2013-07-16 CN CN201380047742.3A patent/CN104937101B/zh not_active Expired - Fee Related
- 2013-07-16 WO PCT/US2013/050744 patent/WO2014014950A1/en not_active Ceased
- 2013-07-16 JP JP2015523191A patent/JP2015524658A/ja active Pending
- 2013-07-16 HK HK15111632.4A patent/HK1211053A1/xx unknown
- 2013-07-16 IN IN849DEN2015 patent/IN2015DN00849A/en unknown
- 2013-07-16 KR KR1020157003982A patent/KR20150032334A/ko not_active Withdrawn
- 2013-07-16 AU AU2013290374A patent/AU2013290374B2/en active Active
- 2013-07-16 EP EP13820187.6A patent/EP2872630B1/en active Active
- 2013-07-16 US US14/415,115 patent/US10793612B2/en active Active
- 2013-07-16 BR BR112015000982A patent/BR112015000982B8/pt not_active IP Right Cessation
- 2013-07-16 RU RU2015104984A patent/RU2015104984A/ru not_active Application Discontinuation
-
2015
- 2015-01-15 IL IL236734A patent/IL236734B/en active IP Right Grant
- 2015-01-20 PH PH12015500107A patent/PH12015500107A1/en unknown
- 2015-01-28 ZA ZA2015/00638A patent/ZA201500638B/en unknown
Non-Patent Citations (3)
| Title |
|---|
| Coding-sequence determinants of gene expression in Escherichia coli;Grzegorz Kudla et al.;《Science》;20090410;第324卷(第5924期);255-258 * |
| Codon usage: Nature"s roadmap to expression and folding of proteins;Evelina Angov;《Biotechnol.J.》;20110512;第6卷(第6期);134-147 * |
| Computational codon optimization of synthetic gene for protein expression;Bevan Kai-Sheng Chung et al.;《BMC Systems Biology》;20121020;第6卷(第1期);650-659 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US10793612B2 (en) | 2020-10-06 |
| IL236734B (en) | 2019-06-30 |
| EP2872630A1 (en) | 2015-05-20 |
| EP2872630A4 (en) | 2016-04-27 |
| AR091774A1 (es) | 2015-02-25 |
| PH12015500107A1 (en) | 2015-03-02 |
| HK1211053A1 (en) | 2016-05-13 |
| CN104937101A (zh) | 2015-09-23 |
| BR112015000982B1 (pt) | 2021-12-28 |
| ZA201500638B (en) | 2017-07-26 |
| RU2015104984A (ru) | 2016-09-10 |
| AU2013290374B2 (en) | 2018-08-09 |
| IN2015DN00849A (cg-RX-API-DMAC7.html) | 2015-06-12 |
| US20150175672A1 (en) | 2015-06-25 |
| IL236734A0 (en) | 2015-02-26 |
| CA2879199A1 (en) | 2014-01-23 |
| BR112015000982A2 (cg-RX-API-DMAC7.html) | 2017-08-15 |
| EP2872630B1 (en) | 2018-10-17 |
| WO2014014950A1 (en) | 2014-01-23 |
| CA2879199C (en) | 2021-08-17 |
| KR20150032334A (ko) | 2015-03-25 |
| JP2015524658A (ja) | 2015-08-27 |
| AU2013290374A1 (en) | 2015-02-19 |
| BR112015000982B8 (pt) | 2023-05-16 |
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