CN104927780A - Cold accumulating agent and preparation method thereof - Google Patents

Cold accumulating agent and preparation method thereof Download PDF

Info

Publication number
CN104927780A
CN104927780A CN201510394729.6A CN201510394729A CN104927780A CN 104927780 A CN104927780 A CN 104927780A CN 201510394729 A CN201510394729 A CN 201510394729A CN 104927780 A CN104927780 A CN 104927780A
Authority
CN
China
Prior art keywords
cold storage
storage agent
gelatin
agent according
sodium chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510394729.6A
Other languages
Chinese (zh)
Inventor
侯亚丽
张东升
李凤霞
张卫东
马红芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Provincial Hospital
Original Assignee
Shandong Provincial Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shandong Provincial Hospital filed Critical Shandong Provincial Hospital
Priority to CN201510394729.6A priority Critical patent/CN104927780A/en
Publication of CN104927780A publication Critical patent/CN104927780A/en
Pending legal-status Critical Current

Links

Landscapes

  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

The invention provides a cold accumulating agent and a preparation method thereof. The cold accumulating agent is composed of, by mass, 1%-8% of glycerol, 1%-5% of inulin, 1%-5% of gelatin, 1%-5% of thickening agent and a sodium chloride water solution. When the cold accumulating agent is prepared, the sodium chloride water solution is heated in a bath to be at the temperature of 70 DEG C, the temperature is kept constant, sodium alginate tech grade, gelatin, inulin and glycerol are sequentially added into the sodium chloride water solution, adding and stirring are performed at the same time when each component is added, and the next component is added after the added component is dissolved evenly; after all the components are added, uniform stirring is performed, the temperature is kept constant for 10 min, and cooling is performed to obtain the cold accumulating agent. The cold accumulating agent can be used repeatedly, and is thick, colloidal, good in fitness, large in latent heat, long in low-temperature duration time, easy to manufacture, low in cost, safe and free of toxicity.

Description

A kind of cold storage agent and preparation method thereof
Technical field
The present invention relates to a kind of cold storage agent, particularly relate to a kind of specialty for the cold storage agent in clinical cold compress therapy.The present invention also comprises its preparation method.
Background technology
Cold storage agent be a kind of by organic or (with) translucent (or opaque) of forming of mineral compound, thickness colloidal mixture, can absorb at low temperatures and store a large amount of cold, and a large amount of cold can be released when temperature is higher, long period maintenance self and low temperature environment interior among a small circle around, cold storage agent is widely used in cold compress therapy.Cold compress therapy is placed in the certain position of human body with the object of refrigeration, local capillary vessel is shunk, alleviates local vascular hyperemia, have anti-inflammatory, hemostasis, pain relieving, skin heat radiation, reduce body temperature effect, thus reach the method for disease therapy, be mainly suitable for malaise symptoms from the beginning of first aid.Current cold storage agent ice bag clinically mainly contains two kinds: one is sodium-chlor ice bag, and this ice bag ice cube hardness is high, and little with body surface local organization contact area, be difficult to fix, low temperature is held time short, needs frequently to change; Another kind is self-cooled ice bag, be loaded on the middle airtight bag cut off by the sal soda added water and ammonium nitrate two kinds of raw materials to form, pull out horizontal folder, by after two kinds of raw material mixing, thermo-negative reaction occurs, reach refrigeration, but this kind of ice bag can only single use, waste raw material, and in handling process, easily damage horizontal folder and make ice bag lose effect to cause transport inconvenience.
summary of the invention:
The present invention aims to provide a kind of cold storage agent and preparation method thereof, and cold storage agent of the present invention can be reused, and for thickness glue can change shape as required after freezing, latent heat greatly, can maintain the low temperature of long period.
To achieve these goals, according to a kind of cold storage agent provided by the invention, be made up of glycerol, inulin, gelatin, thickening material, sodium chloride aqueous solution, each constituent mass degree is: glycerol 1%-8%, inulin 1%-5%, gelatin 1%-5%, thickening material 1%-5%, surplus is sodium chloride aqueous solution.
Preferably, also ammonium chloride is comprised.
Preferably, the mass percent of described ammonium chloride is 5%-10%.
Preferably, described thickening material is one or more in sodium alginate, sodium cellulose glycolate, sodium polyacrylate and carrageenin.
Preferably, described thickening material is sodium alginate.
Preferably, the massfraction of described sodium chloride aqueous solution is 5%-20%.
Preferably, described gelatin is animal gelatin.
Preferably, described gelatin is fishskin gelatin.
Preferably, each constituent mass degree is: glycerol 5%, inulin 5%, gelatin 7%, thickening material 3%, surplus to be massfraction be 15% sodium chloride aqueous solution.
The present invention also provides a kind of preparation method of cold storage agent, comprises the following steps:
(1) constant temperature is kept to carry out following operation to 70 DEG C sodium chloride aqueous solution heating in water bath;
(2) in the sodium chloride aqueous solution in step (1), add sodium alginate, limit edged stirs, and sodium alginate is uniformly dissolved completely;
(3) add gelatin to the solution in step (2), limit edged rapid stirring, makes gelatin be uniformly dissolved completely;
(4) add inulin in the mixed solution obtained to step (3), limit edged stirs, and inulin is also uniformly dissolved completely, obtains the gluey mixed solution of a kind of thickness;
(5) in the gluey mixed solution of thickness of step (4) gained, add glycerol to stir, insulation 10min, namely obtains cold storage agent of the present invention after cooling.
Advantage of the present invention is:
(1) cold storage agent is that thickness is gluey, can free change shape, and docile property is good, is unlikely to again mobility too strong, bad fixing.
(2) cold storage agent can be reused, and saves purchase cost.
(3) cold storage agent latent heat is large, can maintain the low-temperature condition of longer time.
(4) cold storage agent makes simple, and cost is low, safety non-toxic.
Additional aspect of the present invention and advantage will part provide in the following description, and part will become obvious from the following description, or be recognized by practice of the present invention.
Embodiment
Below in conjunction with specific examples, the present invention is described in detail.
embodiment 1
A kind of cold storage agent in the present embodiment, the mass percentage content of each component is: glycerol is 2%, and inulin is 2%, gelatin 1%, sodium alginate 2%, surplus to be massfraction be 15% sodium chloride aqueous solution.
(1) by massfraction be 15% sodium chloride aqueous solution heating in water bath keep constant temperature to carry out following operation to 70 DEG C;
(2) in the sodium chloride aqueous solution in step (1), add sodium alginate, limit edged stirs, and sodium alginate is uniformly dissolved completely;
(3) add gelatin to the solution in step (2), limit edged rapid stirring, makes gelatin be uniformly dissolved completely;
(4) add inulin in the mixed solution obtained to step (3), limit edged stirs, and inulin is also uniformly dissolved completely, obtains the gluey mixed solution of a kind of thickness,
(5) in the gluey mixed solution of thickness of step (4) gained, add glycerol to stir, insulation 10min, namely obtains cold storage agent of the present invention after cooling.
Cold storage agent is placed in-20 DEG C of refrigerator 12h, cools for subsequent use.Measure the latent heat of phase change of different concns solution and transformation temperature with DSC thermal analyzer, the cold storage agent latent heat of phase change recording the present embodiment is 250Kj/Kg, and transformation temperature is 5 DEG C.
embodiment 2
A kind of cold storage agent in the present embodiment, the mass percentage content of each component is: glycerol is 5%, and inulin is 5%, gelatin 4%, sodium alginate 5%, surplus to be massfraction be 20% sodium chloride aqueous solution.The cold storage agent of the present embodiment is obtained according to step in embodiment 1.
Cold storage agent is placed in-20 DEG C of refrigerator 12h, cools for subsequent use.Measure the latent heat of phase change of different concns solution and transformation temperature with DSC thermal analyzer, the cold storage agent latent heat of phase change recording the present embodiment is 242Kj/Kg, and transformation temperature is 4 DEG C.
embodiment 3
A kind of cold storage agent in the present embodiment, the mass percentage content of each component is: glycerol is 3%, and inulin is 2%, gelatin 1%, sodium alginate 3%, ammonium chloride 10%, surplus to be massfraction be 20% sodium chloride aqueous solution.The cold storage agent of the present embodiment is obtained according to step in embodiment 1.
Cold storage agent is placed in-20 DEG C of refrigerator 12h, cools for subsequent use.Measure the latent heat of phase change of different concns solution and transformation temperature with DSC thermal analyzer, the cold storage agent latent heat of phase change recording the present embodiment is 273Kj/Kg, and transformation temperature is 4 DEG C.
embodiment 4
A kind of cold storage agent in the present embodiment, the mass percentage content of each component is: glycerol is 4%, and inulin is 2%, gelatin 1%, sodium alginate 3%, ammonium chloride 6%, surplus to be massfraction be 15% sodium chloride aqueous solution.The cold storage agent of the present embodiment is obtained according to step in embodiment 1.
Cold storage agent is placed in-20 DEG C of refrigerator 12h, cools for subsequent use.Measure the latent heat of phase change of different concns solution and transformation temperature with DSC thermal analyzer, the cold storage agent latent heat of phase change recording the present embodiment is 280Kj/Kg, and transformation temperature is 3 DEG C.
Although illustrate and describe embodiments of the invention, those having ordinary skill in the art will appreciate that: can carry out multiple change, amendment, replacement and modification to these embodiments when not departing from principle of the present invention and aim, scope of the present invention is by claim and equivalents thereof.

Claims (10)

1. a cold storage agent, is characterized in that, is made up of glycerol, inulin, gelatin, thickening material, sodium chloride aqueous solution, and each constituent mass degree is: glycerol 1%-8%, inulin 1%-5%, gelatin 1%-5%, thickening material 1%-5%, and surplus is sodium chloride aqueous solution.
2. a kind of cold storage agent according to claim 1, is characterized in that, also comprise ammonium chloride.
3. a kind of cold storage agent according to claim 2, is characterized in that, the mass percent of described ammonium chloride is 5%-10%.
4. a kind of cold storage agent according to claim 1, is characterized in that, described thickening material is one or more in sodium alginate, sodium cellulose glycolate, sodium polyacrylate and carrageenin.
5. a kind of cold storage agent according to claim 1, is characterized in that, described thickening material is sodium alginate.
6. a kind of cold storage agent according to claim 1, is characterized in that, the massfraction of described sodium chloride aqueous solution is 5%-20%.
7. a kind of cold storage agent according to claim 1, is characterized in that, described gelatin is animal gelatin.
8. a kind of cold storage agent according to claim 5, is characterized in that, described gelatin is fishskin gelatin.
9. a kind of cold storage agent according to claim 1, is characterized in that each constituent mass degree is: glycerol is 5%, and inulin is 5%, gelatin 7%, thickening material 3%, surplus to be massfraction be 15% sodium chloride aqueous solution.
10. the preparation method of a kind of cold storage agent according to any one of claim 1-7, is characterized in that, comprise the following steps:
(1) constant temperature is kept to carry out following operation to 70 DEG C sodium chloride aqueous solution heating in water bath;
(2) in the sodium chloride aqueous solution in step (1), add sodium alginate, limit edged stirs, and sodium alginate is uniformly dissolved completely;
(3) add gelatin to the solution in step (2), limit edged rapid stirring, makes gelatin be uniformly dissolved completely;
(4) add inulin in the mixed solution obtained to step (3), limit edged stirs, and inulin is also uniformly dissolved completely, obtains the gluey mixed solution of a kind of thickness;
(5) in the gluey mixed solution of thickness of step (4) gained, add glycerol to stir, insulation 10min, namely obtains cold storage agent of the present invention after cooling.
CN201510394729.6A 2015-07-08 2015-07-08 Cold accumulating agent and preparation method thereof Pending CN104927780A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510394729.6A CN104927780A (en) 2015-07-08 2015-07-08 Cold accumulating agent and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510394729.6A CN104927780A (en) 2015-07-08 2015-07-08 Cold accumulating agent and preparation method thereof

Publications (1)

Publication Number Publication Date
CN104927780A true CN104927780A (en) 2015-09-23

Family

ID=54115215

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510394729.6A Pending CN104927780A (en) 2015-07-08 2015-07-08 Cold accumulating agent and preparation method thereof

Country Status (1)

Country Link
CN (1) CN104927780A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106543975A (en) * 2016-12-11 2017-03-29 戴琪 A kind of preparation method of low-cost bio matter composite phase-change agent for storage of coldness
CN110484215A (en) * 2019-08-25 2019-11-22 湖南七纬科技有限公司 A kind of cold chain cold-storage material and preparation method thereof
CN113372881A (en) * 2021-05-25 2021-09-10 江苏金合能源科技有限公司 Cold storage material for fruit and vegetable fresh keeping and preparation method thereof
CN114058336A (en) * 2021-11-05 2022-02-18 中煤科工集团沈阳研究院有限公司 Cold storage agent for mine cooling clothes and preparation method thereof
CN114316918A (en) * 2021-12-22 2022-04-12 苏州安特实业有限公司 Degradable biomass coolant and preparation method thereof
CN115368877A (en) * 2022-09-15 2022-11-22 浙江大学 Cold compress material and cold compress assembly based on same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976400A (en) * 1997-09-19 1999-11-02 Thermo Solutions, Inc. Phase change material and use
CN1493644A (en) * 2003-09-09 2004-05-05 上海市印染技术研究所 Environmental protection type cool storage medium
CN103725259A (en) * 2013-12-16 2014-04-16 苏州安特实业有限公司 Repeatedly-usable cold accumulation agent and preparation method thereof
CN104232025A (en) * 2014-10-17 2014-12-24 广州大学 Low-temperature composite phase change cold storage agent and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976400A (en) * 1997-09-19 1999-11-02 Thermo Solutions, Inc. Phase change material and use
CN1493644A (en) * 2003-09-09 2004-05-05 上海市印染技术研究所 Environmental protection type cool storage medium
CN103725259A (en) * 2013-12-16 2014-04-16 苏州安特实业有限公司 Repeatedly-usable cold accumulation agent and preparation method thereof
CN104232025A (en) * 2014-10-17 2014-12-24 广州大学 Low-temperature composite phase change cold storage agent and preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106543975A (en) * 2016-12-11 2017-03-29 戴琪 A kind of preparation method of low-cost bio matter composite phase-change agent for storage of coldness
CN110484215A (en) * 2019-08-25 2019-11-22 湖南七纬科技有限公司 A kind of cold chain cold-storage material and preparation method thereof
CN113372881A (en) * 2021-05-25 2021-09-10 江苏金合能源科技有限公司 Cold storage material for fruit and vegetable fresh keeping and preparation method thereof
CN114058336A (en) * 2021-11-05 2022-02-18 中煤科工集团沈阳研究院有限公司 Cold storage agent for mine cooling clothes and preparation method thereof
CN114316918A (en) * 2021-12-22 2022-04-12 苏州安特实业有限公司 Degradable biomass coolant and preparation method thereof
CN114316918B (en) * 2021-12-22 2023-11-17 苏州安特实业有限公司 Degradable biomass cold accumulation agent and preparation method thereof
CN115368877A (en) * 2022-09-15 2022-11-22 浙江大学 Cold compress material and cold compress assembly based on same

Similar Documents

Publication Publication Date Title
CN104927780A (en) Cold accumulating agent and preparation method thereof
CN103865495B (en) A kind of freezing liquid for infusion process frozen food
CN103194177B (en) For the manufacture method of the ice bag of preservation biological products
CN104726072B (en) A kind of high-efficiency environment friendly low temperature composite phase-change agent for storage of coldness and its preparation method and application
CN102268241A (en) Phase transition material for cooling with phase transition temperature of 12-29 DEG C and preparation method thereof
CN105038715A (en) Hydrous salt cold storage agent with phase-transition temperature of 5-8 DEG C and preparation method thereof
CN106590538B (en) Latent heat cold storage material
CN108251068A (en) A kind of 2-8 DEG C of composite phase-change material and preparation method thereof
CN104232025A (en) Low-temperature composite phase change cold storage agent and preparation method thereof
CN102032749A (en) Code storage device for cold storage and preservation of refrigerator
CN101694338A (en) Ice bag capable of applying in preserving biological product repeatedly and method for preparing the ice bag
CN105601819A (en) Low-temperature gel-state phase-changing cold storage agent and preparation method thereof
CN107722944A (en) A kind of g., jelly-like gel-type Composite low-temperature phase-change cold storage material and preparation method thereof
CN104087253A (en) Coolant for ice bag
CN105395313A (en) Manufacturing method of ultralow-temperature instantaneous cooling ice bag
CN102895059A (en) Phase-change gel-shaped cooling and heating energy bag
JP5705842B2 (en) Cold storage agent
CN103773319A (en) Method for preparing composite phase change coolant
CN104893676A (en) Novel chemical ice bag and preparation method thereof
CN103059816A (en) Efficient phase change energy storage materials and preparation method thereof
CN105255453A (en) Novel cooling storage agent and preparation method thereof
CN103602318A (en) Composite low-temperature phase-change cold storage material
CN101864281A (en) Cold preserving agent and preparation method thereof
CN108264657A (en) A kind of -11 DEG C of nontoxic Phase Change Materials on Storing Energy and preparation method thereof
NL2026475B1 (en) Phase change cold storage agent for strawberry preservation and method for preparing the same

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150923

RJ01 Rejection of invention patent application after publication