CN104922567B - It mends gold plaque and is preparing the application in treating diabetes medicament - Google Patents
It mends gold plaque and is preparing the application in treating diabetes medicament Download PDFInfo
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Abstract
The present invention relates to a kind of new applications of Chinese medicine preparation, that is, mend gold plaque and preparing the application in treating diabetes medicament.Function is with curing mainly:Kidney tonifying benefit lung, strengthening the spleen and reducing phlegm is relieving cough and asthma, QI invigorating, and yin-nourishing is promoted the production of body fluid.For pulmonary tuberculosis, chronic bronchitis, pulmonary emphysema, pulmonary heart disease paracmasis, diabetes.Clinical test shows that benefit gold plaque treatment diabetes curative effect is notable, total effective rate 90.77%, and safety is good, occurs during experiment without any adverse events, is a kind of drug for treating Qi and Yin deficiency diabetes mellitus for being worth marketing.
Description
Technical field
The present invention relates to a kind of new applications of Chinese medicine preparation, that is, mend gold plaque and preparing the application in treating diabetes medicament.
Background technology
Due to the continuous aggravation of the change, in addition aging of population of human dietary variation in recent years and living habit etc., cause
Diabetes morbidity is significantly raised.In numerous methods for the treatment of diabetes, other than keeping on a diet with moderate exercise, Western medicine
Common insulin complement treatment and sulfonylureas drugs for diabetes(Promote pancreatic secretion insulin), biguanides(Promote surrounding group
It knits and utilizes glucose), in process of clinical application, usually there is drug resistance, drug resistance formation, allergic reaction and toxic effect
And have to be reduced or be discontinued.TCM knowledge diabete has the history of more than 4,000 years, is had accumulated in treatment is put into practice a large amount of anti-
Control diabetes(Gu claims diabete)Experience.Traditional Chinese medicine thinks that diabete system is because of body lung, stomach, the bright deficiency of Yin of three dirty heat of kidney, trough
A kind of disease increasingly become thin as primary symptom with polydipsia, rapid digestion of food and polyorexia, urinary micturition, body caused by defeated cloth is not normal.Generally
Diagnosis and treatment are with more than three(More drinks, more foods, diuresis)It distinguishes three to disappear, but this disease is migrated, is related to the integrally-regulated function of yang blood and qi more.Cause
This disease of clinically quenching one's thirst is common with type of deficiency of both QI and YIN, the deficiency of Yin is scorching be the interpretation of the cause, onset and process of an illness key.Thus we with supplementing qi and nourishing yin, promote the production of body fluid
Quench the thirst for method, as prescription foundation.As《Medicine Comprehended-quench one's thirst》Institute's cloud:" three disappear control, it is not necessary to specially according to this warp(On disappear lung,
In disappear stomach, under disappear kidney), but grow its change source, then infirmity is fullyed recover from an illness.”
In the prior art, commercially available benefit gold plaque is produced by Tonghua Maoxiang Pharmaceutical Co., Ltd.(Chinese medicines quasi-word
Z22024860), main ingredient is dried orange peel, Oviductus Ranae, deer horn glue, zaocys dhumnade(Decaptitating is fried), dried human placenta, Oleum Ovum Gallus domesticus Flavus, tangerine
Stalk, colla carapacis et plastri testudinis, the sweet tuber of stemona, fritillaria thunbergii, red ginseng, bletilla, sealwort(It steams), Poria cocos, gekko(Decaptitating, foot), Radix Ophiopogonis, walnut kernel, when
18 taste Chinese medicines is returned to form.With kidney tonifying benefit lung, strengthening the spleen and reducing phlegm, it is relieving cough and asthma the effect of.For pulmonary tuberculosis, chronic bronchial
Inflammation, pulmonary emphysema, pulmonary heart disease paracmasis.
Invention content
A kind of new application for mending gold plaque is provided the purpose of the present invention is being directed to above-mentioned, that is, mends gold plaque and is preparing treatment glycosuria
Application in medicine increases its indication.
The present invention technical solution be:It mends gold plaque and is preparing the application in treating diabetes medicament;The benefit gold
Piece is made of the Chinese medicine of following weight:Dried orange peel 25g, Oviductus Ranae 25g, deer horn glue 15g, zaocys dhumnade(Decaptitating is fried)37.6g, Zi He
Vehicle 125g, Oleum Ovum Gallus domesticus Flavus 25g, campanulaceae 37.5g, colla carapacis et plastri testudinis 12.6g, sweet tuber of stemona 62.6g, fritillaria thunbergii 25g, red ginseng 25g, bletilla
62.6g, sealwort(It steams)62.6g, Poria cocos 25g, gekko(Decaptitating, foot)10g, Radix Ophiopogonis 37.6g, walnut kernel 37.6g, Radix Angelicae Sinensis 25g.
More than 18 tastes, in addition to deer horn glue, colla carapacis et plastri testudinis, Oleum Ovum Gallus domesticus Flavus, gekko, dried human placenta, Oviductus Ranae, fritillaria thunbergii, Radix Angelicae Sinensis,
Ophidia black snake powder is broken into fine powder color;Nine taste such as remaining red ginseng adds water to cook 2 times, is for the first time 3 hours, and second is 2 hours, is merged
Decocting liquid, filtration;Colla carapacis et plastri testudinis, deer horn glue is finely ground, merge with above-mentioned filtrate, be concentrated into relative density as 1.25-1.30(85), add
Enter above-mentioned powder, stir evenly, dry, pulverize, be sieved, add Oleum Ovum Gallus domesticus Flavus, 5% calcium carbonate, 3% peach gum powder, mixing is pressed into 1000
Piece, film coating to get.
Fang Zhongxuan red ginsengs, deer horn glue, gekko(Decaptitating, foot), walnut kernel reinforce vital energy, slake thirst and help produce saliva, nutrition adjusted to defend, tonifying Qi
The benefits of invigorating the spleen rises Yang and benefiting Yin, makes excess syndrome of the lung and degree of having had under one's command, four cloth of body fluid qi and blood, and getter the moon is taken into account, kills two birds with one stone.It is aided with
Colla carapacis et plastri testudinis, sealwort(It steams), zaocys dhumnade(Decaptitating is fried), Oleum Ovum Gallus domesticus Flavus, Radix Ophiopogonis enriching yin and nourishing kidney, consolidate kidney qi, folding degree of having.Nourshing kidney
The moon, and kidney tonifying gas can make to gasify to help, and body fluid must rise, to receive the work(that kidney tonifying effects a permanent cure.It is aided with Radix Angelicae Sinensis, dried human placenta blood-supplementing blood-nourishing benefit
Essence;Nourish Kidney-Yin, campanulaceae, fritillaria thunbergii, sweet stemona root cough relieving resolving sputum and relieving asthma;Poria cocos, dried orange peel invigorating spleen to remove dampness eliminating the phlegm;It is clear let out lung stomach it
Heat, nourishing yin to moisten dryness reach purging the lung of pathogenic fire second of the three ten-day periods of the hot season fire, the purpose of heat evil in clearing stomach, afterwards body fluid it is multiple, it is scorching remove, then rapid digestion of food and polyorexia, thirsty
Disease can remove.Above each medicine compatibility, the effect of playing tonifying Qi altogether, enriching yin, moisturize, promote the production of body fluid, quenching the thirst, hits and quenches one's thirst(Diabetes)The deficiency of Yin
The interpretation of the cause, onset and process of an illness of excess heat, deficiency of both qi and yin achievees the purpose that treat diabetes.
Function is with curing mainly:QI invigorating, yin-nourishing are promoted the production of body fluid.For Qi and Yin deficiency diabetes mellitus.
Specification:Every weight 0.5g
Usage and dosage:It is oral.One time 3,3 times a day, a month as a course for the treatment of.
It is an advantage of the invention that:1. mending gold plaque has kidney tonifying benefit lung, strengthening the spleen and reducing phlegm is relieving cough and asthma, QI invigorating, and yin-nourishing is promoted the production of body fluid
Function.It is applicable not only to pulmonary tuberculosis, chronic bronchitis, pulmonary emphysema, the pulmonary heart disease paracmasis, and to type of deficiency of both QI and YIN glycosuria
Disease also has a better effect.2. clinical test shows that the medicine is significant in efficacy to treatment Qi and Yin deficiency diabetes mellitus, total effective rate reaches
90.77%, and safety is good, occurs during experiment without any adverse events, is that a kind of of marketing is worth to treat gas the moon two
The drug of deficiency diabetes.
The present invention is described in further detail below in conjunction with example.
Specific embodiment
Embodiment
It mends gold plaque and is preparing the application in treating diabetes medicament;Gold plaque is mended to be made of the Chinese medicine of following weight:Dried orange peel
25g, Oviductus Ranae 25g, deer horn glue 15g, zaocys dhumnade(Decaptitating is fried)37.6g, dried human placenta 125g, Oleum Ovum Gallus domesticus Flavus 25g, campanulaceae
37.5g, colla carapacis et plastri testudinis 12.6g, sweet tuber of stemona 62.6g, fritillaria thunbergii 25g, red ginseng 25g, bletilla 62.6g, sealwort(It steams)62.6g, Poria cocos
25g, gekko(Decaptitating, foot)10g, Radix Ophiopogonis 37.6g, walnut kernel 37.6g, Radix Angelicae Sinensis 25g.
More than 18 tastes, in addition to deer horn glue, colla carapacis et plastri testudinis, Oleum Ovum Gallus domesticus Flavus, gekko, dried human placenta, Oviductus Ranae, fritillaria thunbergii, Radix Angelicae Sinensis,
Ophidia black snake powder is broken into fine powder color;Nine taste such as remaining red ginseng adds water to cook 2 times, is for the first time 3 hours, and second is 2 hours, is merged
Decocting liquid, filtration;Colla carapacis et plastri testudinis, deer horn glue is finely ground, merge with above-mentioned filtrate, be concentrated into relative density as 1.25-1.30(85), add
Enter above-mentioned powder, stir evenly, dry, pulverize, be sieved, add Oleum Ovum Gallus domesticus Flavus, 5% calcium carbonate, 3% peach gum powder, mixing is pressed into 1000
Piece, film coating to get.
Experimental example
Clinical test
Subject's gender, age condition
Age-sex | 30-40 Sui | 41-50 Sui | 51-60 Sui | 61-75 Sui | It is total |
Male | 8 | 10 | 29 | 13 | 60 |
Women | 13 | 23 | 19 | 15 | 70 |
It is total | 21 | 33 | 48 | 28 | 130 |
More than in 130 subjects, man 60, female 70;Wherein 30-40 Sui 21,41-50 Sui 33,51-60 Sui
48,61-75 Sui 28.
Diagnosis basis, syndrome-classification, efficacy evaluation:It is treated with reference to People's Republic of China's traditional Chinese medicine industry standard disease diagnosis
Quasi- the quenching one's thirst for ZY/T001.1-94 of criterion and formulate.
It quenches one's thirst by insufficiency of natural endowment, caused by the deficiency of Yin is scorching.Thirst and drinking is above disappears;Bulimia disappears in being;Drink one, which is urinated, one is
Under disappear, general designation is quenched one's thirst.Including diabetes, diabetes insipidus.
Diagnosis basis
Polydipsia, polyorexia, urinary micturition, body are become thin.
From the beginning of symptom can not being write " more than three ".Sick Chang Bingfa dizziness long, tuberculosis, the obstruction of qi in the chest, apoplexy, night blindness, boil etc..Severe patient
It can be seen that polydipsia, has a headache, vomiting, abdominal pain is short of breath, the de- crisis even stupor is fainted.
Look into empty stomach, postprandial 2 hours glucoses in urine and blood glucose, specific gravity of urine, dextrose tolerance test.Have urine examined ketoboidies when necessary, blood urine
Plain nitrogen, creatinine, carbon dioxide combining power and blood potassium, sodium, calcium, chloride etc..
Syndrome-classification
Dry-heat impairing lung:Polydipsia and polydipsia, dry mouth and throat, polyorexia, urine measure more, dry and hard excrement.Red tongue body, moss thin yellow,
Rapid pulse.
Stomach dryness and thin fluid injury:Rapid digestion of food and polyorexia, constipation, dry are intended to drink, and body is become thin.Red tongue with yellowish fur, slippery are strong.
Kidney deficiency:Urinary micturition mixes such as fat, has a dizzy spell, tinnitus, blurred vision, dry mouth and lips, and insomnia is vexed.
The red few tongue of tongue, the thin chord number of arteries and veins.
It is yin-yang deficiency:Frequent micturition, drink one urinate one, color contamination such as cream.Darkish complexion, helix is dried-up, soreness and weakness of waist and knees, becomes thin significantly,
Impotence or irregular menstruation, chilly face are floated.Pale tongue, tongue is white, deep,thready and forceless pulse.
Floating of yang due to yin deficiency:Urinary micturition, polydipsia is flushing, katzeniammer, and mouth has peculiar smell, and the thin bone of shape is stood, the red dry of lip, and breathing is deep
Soon.Or coma mist, peripheral coldness.Crimson tongue, tongue ash or burned black, faint and rapid pulse disease.
Efficacy evaluation
It is effective:Symptom disappears, and laboratory examination is repeatedly normal.
Effectively:Cardinal symptom and related laboratory examination have improvement.
In vain:Symptom and laboratory examination it is unchanged or aggravate.
Usage and dosage:It is oral.One time 3,3 times a day, a month as a course for the treatment of, treat a course for the treatment of.
Mend the clinical efficacy of gold plaque treatment diabetes
Clinical test results show that benefit gold plaque treatment diabetes curative effect is notable, total effective rate 90.77%, and safety is good,
Occur during experiment without any adverse events, be a kind of drug for treating Qi and Yin deficiency diabetes mellitus for being worth marketing.
Claims (1)
1. mending gold plaque is preparing the application in treating diabetes medicament;The benefit gold plaque is made of the Chinese medicine of following weight:It is old
Skin 25g, Oviductus Ranae 25g, deer horn glue 15g, zaocys dhumnade 37.6g, dried human placenta 125g, Oleum Ovum Gallus domesticus Flavus 25g, campanulaceae 37.5g, tortoise are fried
First glue 12.6g, sweet tuber of stemona 62.6g, fritillaria thunbergii 25g, red ginseng 25g, bletilla 62.6g, sealwort 62.6g, Poria cocos 25g, gekko are steamed
10g, Radix Ophiopogonis 37.6g, walnut kernel 37.6g, Radix Angelicae Sinensis 25g.
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Citations (1)
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CN101167992A (en) * | 2007-10-13 | 2008-04-30 | 罗玉文 | Cool health-care beer capable of balanced fat-reducing, overall preventing cough and diabetes and beautifying |
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KR101144059B1 (en) * | 2008-07-30 | 2012-05-23 | 고려대학교 산학협력단 | Composition for prevention or treatment of diabete or obesity comprising Punica granatum extract and red ginseng extract |
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CN101167992A (en) * | 2007-10-13 | 2008-04-30 | 罗玉文 | Cool health-care beer capable of balanced fat-reducing, overall preventing cough and diabetes and beautifying |
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