CN104922404A - External-use medicine for treating hyperostosis and preparation method thereof - Google Patents
External-use medicine for treating hyperostosis and preparation method thereof Download PDFInfo
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Abstract
The invention relates to external-use medicine for treating hyperostosis and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The external-use medicine for treating the hyperostosis is mainly composed of, by weight, the following components of 10-20 parts of camphor, 15-25 parts of gardenias, 10-20 parts of Chinese chives, 15-25 parts of fermented glutinous rice, 10-20 parts of borneol and 25-35 parts of vaseline. The external-use medicine comprises the camphor, the borneol, the gardenias and the like of set weight parts. All the components are used in cold and heat and achieve the effects of invigorating the circulation of blood and eliminating stagnant blood and activating meridians to stop pain together, and the external-use medicine can mainly treat pain, numbness and other symptoms caused by hyperostosis nerve oppression. An external application medicine application mode can be adopted in the external-use medicine, the medicine directly reaches an affected part, the medicine effect is remarkable, medicine application is direct, and pain cannot be caused to a patient. In addition, the external-use medicine is prepared through grinding, mixing, stirring and other preparation, and the whole preparation method is easy, feasible and low in cost.
Description
Technical field
The present invention relates to the field of Chinese medicines, in particular to a kind of medicine for external use for the treatment of hyperosteogeny and preparation method thereof.
Background technology
Hyperosteogeny (Hypertrophic osteoarthritis) refers to due to degeneration of joint, so that the chronic joint disease that articular cartilage is destroyed and causes.Also known as osteoarthritis, osteoarthritis and hypertrophiarthritis etc.
Hypertrophic osteoarthritis has constitutional and Secondary cases two kinds.Constitutional is also known as idiopathic, aging based on human body natural, more rare; Secondary cases is then based on chronic strain and the wound day after tomorrow, more common.The Basic disease cause of constitutional osteoarthritis is the aging gradually and degeneration after people's body maturation, the performance in osteoarthrosis.Secondary osteoarthrosis refers to because of certain known reason, such as wound, operation or other obvious factors and the cartilage destruction that causes, or articulation structure changes.Due to factors such as articular surface friction or pressure imbalances, cause the degeneration of articular surface.
Hyperosteogeny onset is slow, without General Symptoms, mostly is the person in middle and old age of more than 50 years old.Be often multi-joint morbidity, also have simple joint to send out patient.Affected joints can have persistence dull pain, increases the weight of during movable increase, takes a turn for the better after having a rest.Pain is often not serious, increases the weight of when air pressure reduces, relevant with climate change.Sometimes can there is acute pain episodes, have joint stiff sense simultaneously, can find that intraarticular has crunch once in a while.Sitting posterior joint is stiff to be increased the weight of, and take a turn for the better after slightly movable, someone is referred to as " rest pain ".Later stage arthroncus, increase and limitation of movement, little complete tetanus, generally shows as bone retardance and levies
In correlation technique, be subtract pauciarticular heavy burden and excessive significantly activity for the most important Therapeutic Method the most basic again of hyperosteogeny, treasure diseased joints, to delay the process of pathological changes.Overweight people should lose weight, and to subtract pauciarticular load, delays the development of pathological changes.Can with crutch or walking stick when joint of the lower extremity has a pathological changes, to alleviate the burden in joint.
In addition, patient can also do physical therapy and suitable exercise, to keep the range of activity in joint, can use clamping plate brace and walking stick etc. if desired, contributes to controlling acute stage symptom.In the medicine for the treatment of hyperosteogeny, generally comparatively common with the medicine for external use of anti-inflammatory analgesic, but, anti-inflammation and analgesic drugs can alleviate or control symptom, but it cannot directly act on affected part, the progress of pathological changes can not be changed, just during acute pain episodes, work the effect of taking stopgap measures.In addition, to comparatively serious patient, under the condition of systemic conditions energy tolerate surgery, carry out that artificial joint replacement is eliminate pain, correction deformity, improve the effective ways of bone function, but the method cost is high, the misery caused patient is comparatively large, and the postoperative time needing to recuperate is long.
In view of this, special proposition the present invention.
Summary of the invention
An object of the present invention is to provide a kind of medicine for external use for the treatment of hyperosteogeny, and the medicine for external use of this treatment hyperosteogeny comprises the Camphora of set composition by weight, Borneolum Syntheticum and Fructus Gardeniae etc.; The symptoms such as all medicine simultaneously using both cold and hot drugs play promoting blood circulation to remove blood stasis altogether, and effect of removing obstruction in the collateral to relieve pain can cure mainly the pain caused by hyperosteogeny pressuring nerve, numb; This medicine for external use can adopt the application method of external application, and medicine is gone directly affected part, and drug effect is obvious.
The second object of the present invention is to provide the preparation method of the medicine for external use of above-mentioned treatment hyperostosis wound, the method adopts the operations such as grinding, mixing and stirring to achieve the preparation of this medicine for external use, and whole preparation method is simple, and cost is low, and medication is direct, can not cause suffering to patient.
In order to realize above object, spy of the present invention by the following technical solutions:
Treat a medicine for external use for hyperosteogeny, according to weight parts, it is made primarily of following component:
Camphora 10 ~ 20 parts, Fructus Gardeniae 15 ~ 25 parts, 10 ~ 20 parts, Folium Allii tuberosi, glutinous rice wine 15 ~ 25 parts, Borneolum Syntheticum 10 ~ 20 parts, 25 ~ 35 parts, vaseline.
In this medicine for external use, Camphora: Xin Wen, external has antipruritic, pain relieving, the effect of local anaesthesia; Borneolum Syntheticum: Xin Han.Clearing away heat to alleviate pain; Fructus Gardeniae: bitter cold.Reducing swelling and alleviating pain.Described in Compendium of Material Medica " ... traumatic blood stasis ".Folium Allii tuberosi: abnormal smells from the patient is pungent, has removing blood stasis and activating blood flow, the effect of circulation of qi promoting intestinal stasis relieving, can external curing traumatic injury, swelling and pain due to blood stasis.Glutinous rice wine: Xin Wenxiang falls apart.There is damp eliminating of dispeling cold, effect of blood circulation promoting and blood stasis dispelling.Vaseline has the effect bonding all medicines, is convenient to external used medicine and forms given shape.After set part by weight compatibility, each component plays drug effect jointly, and all medicine simultaneously using both cold and hot drugs play promoting blood circulation to remove blood stasis altogether, effect of removing obstruction in the collateral to relieve pain.The pain caused by hyperosteogeny pressuring nerve can be cured mainly, the symptoms such as numbness; And this medicine for external use can adopt the application method of external application, medicine is gone directly affected part, and drug effect is obvious.
Preferably, according to weight parts, this medicine for external use its make primarily of following component:
Camphora 12 ~ 18 parts, Fructus Gardeniae 18 ~ 22 parts, 12 ~ 17 parts, Folium Allii tuberosi, glutinous rice wine 18 ~ 22 parts, Borneolum Syntheticum 12 ~ 15 parts, 28 ~ 32 parts, vaseline.Have the medicine for external use of said ratio, its drug effect is particularly remarkable.
Preferably, in order to the promoting blood circulation to remove blood stasis and analgesic effect making this medicine for external use is better, Moschus 0.04 ~ 0.08 part of component as this medicine for external use can be selected.Moschus: Xin Wen, promoting blood circulation to remove blood stasis and pain relieving.Described in Compendium of Material Medica " ... open meridians, saturating flesh bone "; After it is with set parts by weight and Camphora and Fructus Gardeniae mixture, can give that medicine for external use is antipruritic, pain relieving, detumescence and local anesthesia effect.
Prepare a method for the medicine for external use for the treatment of hyperosteogeny, comprise the steps:
1), by mixing after Camphora, Borneolum Syntheticum, Fructus Gardeniae grinding, the first material is obtained;
2) with described first mixing of materials after, by Folium Allii tuberosi smashing to pieces, the second material is obtained;
3), in described second material add glutinous rice wine and vaseline, and be stirred to pasty state, obtain the medicine for external use being used for the treatment of hyperosteogeny.
This preparation method adopts grinding, smash to pieces and different medicine materials is made the medicine for external use that can be used for treating hyperosteogeny by the operating procedure such as stirring; The method is simple to operate, is easy to control, and preparation cost is low, makes the cost of the medicine for external use made also corresponding lower.
In addition, for this medicine for external use, in the process used, applied at affected part (painful area), and selected the application number of times of every day and the natural law for the treatment of depending on rehabilitation state.
In addition, in the process of concrete preparation, step 1) in Camphora, Borneolum Syntheticum, Fructus Gardeniae can mix rear grinding, remix after also can grinding respectively.In step 2) in, smash operation to pieces for Folium Allii tuberosi, preferably smash to pasty state by Folium Allii tuberosi, the effective ingredient like this contained by it can be separated out completely as much as possible, is beneficial to the drug effect improving medicine for external use.
In further technical scheme, in order to the effect making the medicine for external use made have better antipruritic, pain relieving, detumescence and local anesthesia, preferably, in step 3) in, specifically comprise:
In described second material, first add glutinous rice wine and vaseline, after being stirred to pasty state, applying Moschus on the surface of pasty mixture, obtain medicine for external use.Moschus is in the surface of pasty mixture, is beneficial to very much Moschus like this and directly infiltrates affected part in the process of medication, thus improves curative effect.
Further preferably, in step 3) in, specifically comprise:
In described second material, first add glutinous rice wine and vaseline, and with gauze bag parcel after being stirred to pasty state, applying Moschus on the surface of gauze bag, obtain medicine for external use.
For the patient needing the application time longer, Borneolum Syntheticum is easy to melt, thus makes medicine for external use thinning, is unfavorable for docile; Therefore in the process of preparation, by add in the second material rice wine and vaseline it, and with gauze bag parcel after being stirred to pasty state, then apply Moschus on the surface of gauze bag, obtain medicine for external use; By gauze, all medicines are integrated in one, prevent it from disperseing.And spray on gauze bag surface due to Moschus, when medication, the Moschus on surface can directly contact with affected part, achieves under the prerequisite of the infiltration rate accelerating medicine, prevents medicine for external use from growing due to the drug of topical application time and rare situation scattered of faling apart of causing.
In addition, in order to accelerate the preparation efficiency of medicine for external use, and make each component grinding of medicine for external use abundant, preferably, described grinding utilizes mortar to complete.
Preferably, in step 2) in: in the process of described mixing, the Folium Allii tuberosi smashed to pieces and described first material are stirred.By stirring operation, can make the Folium Allii tuberosi smashed to pieces and the first mixing of materials abundant.
Preferably, in step 3) in, described stirring adopts blender to complete.
Whipping process adopts pony mixer or food blending machine, to improve the efficiency of stirring, saves time, and is beneficial to each component mixing fully.
Preferably, in step 3) in, the alcoholic strength of described glutinous rice wine is 5% ~ 15%.
Alcoholic strength is the glutinous rice wine of 5% ~ 15%, can help the damp eliminating of dispeling cold improving medicine for external use, the effect of blood circulation promoting and blood stasis dispelling with after other component mixtures; But also there is the effect helping improve Fructus Gardeniae reducing swelling and alleviating pain.
Compared with prior art, technique effect of the present invention comprises the following aspects:
1) symptoms such as, this medicine for external use selects rationally appropriate due to component, gives it and has promoting blood circulation to remove blood stasis, effect of removing obstruction in the collateral to relieve pain, can cure mainly the pain caused by hyperosteogeny pressuring nerve, numb.
2), this medicine is medicine for external use, and medication is convenient, and affected part of can going directly, therefore has better drug effect.
3), this medicine components is Chinese medicine, and it is harmless to human-body safety, and has effect of effecting a permanent cure, and compared with the mode of traditional operative treatment hyperosteogeny, has cost-saving, can reduce the advantage of patient suffering.
4), the preparation technology of whole medicine for external use is simple, is easy to operation, without the need to special main equipment, and then makes the with low cost of whole preparation process.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted preparation manufacturer person of instrument, be and can buy by commercially available the conventional products obtained.
The invention provides a kind of medicine for external use for the treatment of hyperosteogeny, according to weight parts, it is made primarily of following component:
Camphora 10 ~ 20 parts, Fructus Gardeniae 15 ~ 25 parts, 10 ~ 20 parts, Folium Allii tuberosi, glutinous rice wine 15 ~ 25 parts, Borneolum Syntheticum 10 ~ 20 parts, 25 ~ 35 parts, vaseline.Preferably, its component comprises: Camphora 12 ~ 18 parts, Fructus Gardeniae 18 ~ 22 parts, 5 ~ 7 parts, Folium Allii tuberosi, glutinous rice wine 18 ~ 22 parts, Borneolum Syntheticum 12 ~ 15 parts, 28 ~ 32 parts, vaseline.In addition, in order to improve the effect of outer promoting blood circulation to remove blood stasis obstinately, preferably, medicine components also comprises 0.04 ~ 0.08 part, Moschus.
Method for the preparation of above-mentioned medicine for external use provided by the invention, it comprises the following steps:
1), by mixing after Camphora, Borneolum Syntheticum, Fructus Gardeniae grinding, the first material is obtained;
2) with described first mixing of materials after, by Folium Allii tuberosi smashing to pieces, the second material is obtained;
3), in described second material add glutinous rice wine and vaseline, and be stirred to pasty state, obtain the medicine for external use being used for the treatment of hyperosteogeny.
The method is first by mixing after Camphora, Borneolum Syntheticum, Fructus Gardeniae grinding, the effective ingredient of this three herbal medicine is mixed, secondly the first material be made up of this three herbal medicine mixes with Folium Allii tuberosi, obtain the second material, add glutinous rice wine and vaseline again in second material, by stir and vaseline adhesive effect so that obtain pasty state and can the medicine for external use of direct docile.
Next, following specific embodiment is enumerated to medicine for external use for the treatment of hyperosteogeny provided by the invention and preparation method thereof:
Embodiment 1
Mixing after Camphora 10g, Borneolum Syntheticum 10g, Fructus Gardeniae 15g being ground, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 10g, obtain the second material;
In described second material, add glutinous rice wine 15g and vaseline 25g, and be stirred to pasty state, obtain the medicine for external use being used for the treatment of hyperosteogeny.
Embodiment 2
Camphora 20g, Borneolum Syntheticum 20g, Fructus Gardeniae 25g are mixed after utilizing mortar grinder respectively, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 20g, obtain the second material;
In described second material, add glutinous rice wine 25g and vaseline 35g, and be stirred to pasty state, and spread Moschus 0.08g on the surface of pasty mixture, obtain the medicine for external use being used for the treatment of hyperosteogeny.
Embodiment 3
Camphora 15g, Borneolum Syntheticum 15g, Fructus Gardeniae 20g are mixed after utilizing mortar grinder respectively, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 15g, obtain the second material;
In described second material, add glutinous rice wine 20g and vaseline 30g, and with gauze bag parcel after being stirred to pasty state, applying Moschus 0.06g on the surface of gauze bag, to obtain final product.
Embodiment 4
Camphora 18g, Borneolum Syntheticum 22g, Fructus Gardeniae 20g are mixed after utilizing mortar grinder respectively, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 17g, obtain the second material;
In described second material, add glutinous rice wine 17g and vaseline 25g, and with gauze bag parcel after being stirred to pasty state, applying Moschus 0.05g on the surface of gauze bag, obtain the medicine for external use being used for the treatment of hyperosteogeny.
Embodiment 5
After Camphora 18g, Borneolum Syntheticum 22g, Fructus Gardeniae 20g being mixed, after utilizing mortar grinder together, obtain the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 17g, obtain the second material;
Glutinous rice wine 16g (alcoholic strength is 10%) and vaseline 25g is added in described second material, and with gauze bag parcel after hand operated mixing to pasty state, and apply Moschus 0.05g on the surface of gauze bag, obtain the medicine for external use being used for the treatment of hyperosteogeny.
Embodiment 6
Camphora 150g, Borneolum Syntheticum 150g, Fructus Gardeniae 200g are mixed after utilizing mortar grinder respectively, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 150g, obtain the second material;
In described second material, add glutinous rice wine 250g and vaseline 350g, wrap up with gauze bag after utilizing pony mixer to be stirred to pasty state, and apply Moschus 0.8g on the surface of gauze bag, obtain the medicine for external use being used for the treatment of hyperosteogeny.
Embodiment 7
Camphora 200g, Borneolum Syntheticum 200g, Fructus Gardeniae 250g are mixed after utilizing mortar grinder respectively, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 180g, obtain the second material;
Glutinous rice wine 250g (alcoholic strength is 5%) and vaseline 350g is added in described second material, and wrap up with gauze bag after utilizing pony mixer to be stirred to pasty state, and apply Moschus 0.8g on the surface of gauze bag, obtain the medicine for external use being used for the treatment of hyperosteogeny.
Embodiment 8
Camphora 100g, Borneolum Syntheticum 200g, Fructus Gardeniae 200g are mixed after utilizing mortar grinder respectively, obtains the first material; With described first mixing of materials after being smashed to pieces by Folium Allii tuberosi 190g, obtain the second material;
Glutinous rice wine (alcoholic strength is 15%) 150g and vaseline 300g is added in described second material, wrap up with gauze bag after utilizing pony mixer to be stirred to pasty state, and apply Moschus 0.6g on the surface of gauze bag, obtain the medicine for external use being used for the treatment of hyperosteogeny.
For the medicine for external use that can be used for treating hyperosteogeny that above-described embodiment is prepared into, in the process used, the medicine for external use provided with embodiment 1-5 is subsides, and pastes once every three days again, and general 3 paste and can fully recover.
Case 1
Literary composition so-and-so, female, 58 years old.Lumbago and skelalgia 3 months, limitation of activity.Find through x-ray inspection at county hospital Orthopeadic Surgery, the 5th, 6 lumbar vertebra hyperosteogeny.By carrying out lumbar traction and Drug therapy one month, but less effective.Paste pain with this side (embodiment 3 provides) afterwards obviously to alleviate, two paste rear all diseases all disappears and accuses recovery from illness.
Case 2
Pueraria lobota so-and-so.Man, 62 years old.Headache, dizzy, left arm numb half a year.Find the 3rd, 4,5 hyperosteogeny of cervical vertebra in the People's Hospital of city through x-ray inspection, and have no positive effect through traction and acupuncture and moxibustion therapy.Still see that dizziness headache is with feeling sick, left arm is especially heavy for numb night, then arrives here after this prescription (embodiment 3 provides) external application for curing three pastes, no headache, dizzy and numb, not yet recurs so far.
Case 3
Section so-and-so, female, 55 years old.With the right gonalgia, bend and stretch walking unfavorable, find right knee joint patella hyperosteogeny to county people's hospital through x-ray inspection.Through hormone, have no improvement after analgesic treatment, pasted after (embodiment 1 provides) through this side's external application for curing three afterwards, pain symptom all disappears, and activity freely.
In sum, the medicine for external use of this treatment hyperosteogeny provided by the invention, the symptoms such as all medicines (component) simultaneously using both cold and hot drugs plays promoting blood circulation to remove blood stasis altogether, and effect of removing obstruction in the collateral to relieve pain can cure mainly the pain caused by hyperosteogeny pressuring nerve, numb; This medicine for external use can adopt the application method of external application, and medicine is gone directly affected part, and drug effect is obvious.Overcome artificial joint replacement cost high, the misery caused patient is comparatively large, and the postoperative defect needing the time of recuperation long.
Although illustrate and describe the present invention with specific embodiment, however it will be appreciated that can to make when not deviating from the spirit and scope of the present invention many other change and amendment.Therefore, this means to comprise all such changes and modifications belonged in the scope of the invention in the following claims.
Claims (10)
1. treat a medicine for external use for hyperosteogeny, it is characterized in that, according to weight parts, it is made primarily of following component:
Camphora 10 ~ 20 parts, Fructus Gardeniae 15 ~ 25 parts, 10 ~ 20 parts, Folium Allii tuberosi, glutinous rice wine 15 ~ 25 parts, Borneolum Syntheticum 10 ~ 20 parts, 25 ~ 35 parts, vaseline.
2. the medicine for external use for the treatment of hyperosteogeny as claimed in claim 1, it is characterized in that, according to weight parts, it is made primarily of following component:
Camphora 12 ~ 18 parts, Fructus Gardeniae 18 ~ 22 parts, 5 ~ 7 parts, Folium Allii tuberosi, glutinous rice wine 18 ~ 22 parts, Borneolum Syntheticum 12 ~ 15 parts, 28 ~ 32 parts, vaseline.
3. the medicine for external use for the treatment of hyperosteogeny as claimed in claim 1 or 2, it is characterized in that, its component also comprises: 0.04 ~ 0.08 part, Moschus.
4. prepare a method for the medicine for external use for the treatment of hyperosteogeny, it is characterized in that, comprise the steps:
1), by mixing after Camphora, Borneolum Syntheticum, Fructus Gardeniae grinding, the first material is obtained;
2) with described first mixing of materials after, by Folium Allii tuberosi smashing to pieces, the second material is obtained;
3), in described second material add glutinous rice wine and vaseline, and be stirred to pasty state, obtain the medicine for external use being used for the treatment of hyperosteogeny.
5. the method for the medicine for external use of preparation treatment hyperosteogeny as claimed in claim 4, is characterized in that, in step 3) in, specifically comprise:
In described second material, first add glutinous rice wine and vaseline, after being stirred to pasty state, applying Moschus on the surface of pasty mixture, obtain medicine for external use.
6. the method for the medicine for external use of preparation treatment hyperosteogeny as claimed in claim 4, is characterized in that, in step 3) in, specifically comprise:
In described second material, first add glutinous rice wine and vaseline, and with gauze bag parcel after being stirred to pasty state, applying Moschus on the surface of gauze bag, obtain medicine for external use.
7. the method for the medicine for external use of the preparation treatment hyperosteogeny as described in any one of claim 4-6, is characterized in that, in step 1) in, described grinding utilizes mortar to complete.
8. the method for the medicine for external use of preparation treatment hyperosteogeny as claimed in claim 7, is characterized in that, in step 2) in, in the process of described mixing, the Folium Allii tuberosi smashed to pieces and described first material are stirred.
9. the method for the medicine for external use of preparation treatment hyperosteogeny as claimed in claim 7, is characterized in that, in step 3) in, described stirring adopts blender to complete.
10. the method for the medicine for external use of preparation treatment hyperosteogeny as claimed in claim 7, is characterized in that, in step 3) in, the alcoholic strength of described glutinous rice wine is 5% ~ 15%.
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