CN1048978A - The vaginal lubricant and the preparation method that are used for pudendum - Google Patents
The vaginal lubricant and the preparation method that are used for pudendum Download PDFInfo
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- CN1048978A CN1048978A CN 89105335 CN89105335A CN1048978A CN 1048978 A CN1048978 A CN 1048978A CN 89105335 CN89105335 CN 89105335 CN 89105335 A CN89105335 A CN 89105335A CN 1048978 A CN1048978 A CN 1048978A
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- glycerol
- vitamin
- solution
- mel
- liquid paraffin
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- 239000000314 lubricant Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title abstract description 29
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 62
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 57
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 40
- 229940057995 liquid paraffin Drugs 0.000 claims abstract description 25
- 239000011780 sodium chloride Substances 0.000 claims abstract description 20
- 238000003756 stirring Methods 0.000 claims abstract description 16
- 210000003905 vulva Anatomy 0.000 claims abstract description 7
- 239000000243 solution Substances 0.000 claims description 30
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 28
- 239000007864 aqueous solution Substances 0.000 claims description 19
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 17
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 17
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 17
- 235000019155 vitamin A Nutrition 0.000 claims description 17
- 239000011719 vitamin A Substances 0.000 claims description 17
- 229940045997 vitamin a Drugs 0.000 claims description 17
- 229930003427 Vitamin E Natural products 0.000 claims description 14
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 14
- 235000019165 vitamin E Nutrition 0.000 claims description 14
- 229940046009 vitamin E Drugs 0.000 claims description 14
- 239000011709 vitamin E Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- NJTGANWAUPEOAX-UHFFFAOYSA-N molport-023-220-454 Chemical compound OCC(O)CO.OCC(O)CO NJTGANWAUPEOAX-UHFFFAOYSA-N 0.000 claims description 8
- 150000001875 compounds Chemical class 0.000 claims description 2
- 239000002075 main ingredient Substances 0.000 claims description 2
- 229960002668 sodium chloride Drugs 0.000 claims 6
- 235000002639 sodium chloride Nutrition 0.000 claims 6
- 238000000034 method Methods 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000011259 mixed solution Substances 0.000 claims 1
- 230000001568 sexual effect Effects 0.000 abstract description 16
- 210000001215 vagina Anatomy 0.000 abstract description 14
- 229940088594 vitamin Drugs 0.000 abstract description 9
- 229930003231 vitamin Natural products 0.000 abstract description 9
- 235000013343 vitamin Nutrition 0.000 abstract description 9
- 239000011782 vitamin Substances 0.000 abstract description 9
- 150000003722 vitamin derivatives Chemical class 0.000 abstract description 9
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 8
- 241000282414 Homo sapiens Species 0.000 abstract description 5
- 230000001954 sterilising effect Effects 0.000 abstract description 5
- 239000003795 chemical substances by application Substances 0.000 abstract description 4
- 210000003756 cervix mucus Anatomy 0.000 abstract description 3
- 230000035807 sensation Effects 0.000 abstract description 3
- 230000036074 healthy skin Effects 0.000 abstract description 2
- 239000006210 lotion Substances 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 18
- 230000000694 effects Effects 0.000 description 13
- 235000011187 glycerol Nutrition 0.000 description 13
- 239000003814 drug Substances 0.000 description 10
- 239000011647 vitamin D3 Substances 0.000 description 10
- 229940021056 vitamin d3 Drugs 0.000 description 10
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 9
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 9
- 235000005282 vitamin D3 Nutrition 0.000 description 9
- 230000036541 health Effects 0.000 description 8
- 238000010521 absorption reaction Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 6
- 238000012856 packing Methods 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 239000011575 calcium Substances 0.000 description 3
- 229910052791 calcium Inorganic materials 0.000 description 3
- 210000000981 epithelium Anatomy 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000005461 lubrication Methods 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 239000012188 paraffin wax Substances 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 235000012907 honey Nutrition 0.000 description 2
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- 210000004877 mucosa Anatomy 0.000 description 2
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- 239000003921 oil Substances 0.000 description 2
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- 229940099259 vaseline Drugs 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000222336 Ganoderma Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
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- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
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- 239000010839 body fluid Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- SOROIESOUPGGFO-UHFFFAOYSA-N diazolidinylurea Chemical compound OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O SOROIESOUPGGFO-UHFFFAOYSA-N 0.000 description 1
- 229960001083 diazolidinylurea Drugs 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
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- 208000001848 dysentery Diseases 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000001076 estrogenic effect Effects 0.000 description 1
- 231100001076 gonad atrophy Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000008297 liquid dosage form Substances 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
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- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 210000002640 perineum Anatomy 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
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- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
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Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a kind of vaginal lubricant that is applied to the female vulva position, is the nourishing healthy skin lotion that is used to improve the human sexuality.This lubricant is by liquid paraffin, glycerol, Mel, sodium chloride and acetum and multivitamin are formed, and its preparation method is earlier vitamin to be dissolved in the liquid paraffin, dissolve Mel and add acetic acid and glycerol with sodium chloride solution in addition, again two kinds of solution are mixed stirring, again through sterilization.This agent can make the lubricious softness of pudendum, and vagina moistens and strengthens elasticity, helps to overcome owing to vaginal secretion reduces the misery that causes, and eliminates person in middle and old age and the part young women feared state of mind to sexual life, and is comfortable during sexual life, and pleasant sensation makes sexual life more smooth satisfactory.
Description
The present invention relates to a kind of human sexuality's of being used for nourishing healthy skin moistening liquid, be to be coated with the vaginal lubricant that is used for the pudendum position, middle aged and aged women is along with estrogenic minimizing, secretion capacity reduces, it is dry and astringent that vagina becomes gradually, and vaginal wall becomes fragile, and follows the string, can be during sexual life because of pain produce being sick of and the feared state of mind of sexual life, some young women also has analogue because of vaginal secretion is less.As using pudendum and vaginal lubricant, can remedy this shortcoming during sexual life, make sexual life harmonious happy, be of value to both sides' physical and mental health.According to the preliminary search result, at present still useless in the vaginal lubricant of pudendum, purpose only is that these type of cosmetics of skin moistening do not find yet.Understand according to the inventor, at present, come lubrication assistant with glycerol (glycerol) when people's sexual intercourse is arranged, but the glycerine lubrication degree is not enough, and water absorption is arranged, can make the dry and astringent vagina of user more uncomfortable, in addition, Oleum sesami, vaseline is than thickness, pollution clothes is difficult for washing, and is therefore, also inapplicable.
Purpose of the present invention, provide being used for pudendum and when sexual intercourse, entering the lubricant of vagina of a kind of human sexuality of improvement, it makes the lubricious softness of skin of vulva, and vagina moistens, and increases elasticity, non-stimulated to vagina epithelium, help to overcome owing to secretion reduces the misery that causes, eliminate person in middle and old age and a part of young women the feared state of mind for sexual life, and comfortable with the back, increase pleasant sensation, make sexual life satisfactory smoothly.The present invention to product requirement is: the lubricant diffusibility that is provided is good, can spread the fold that is impregnated into skin effectively, and stricture of vagina such as splits at the place; PH value is suitable, can suppress germ reproduction effectively, helps the vagina health care, and another requirement of lubricant of the present invention is not pollute skin, and medicated clothing is convenient to be coated with exhibition, washing, and health during use, convenient and be convenient to long preservation.In addition, lubricant provided by the present invention can also satisfy following well-known purpose and requirement: nontoxic to health, harmless, have no side effect, and there is not the poisoning of savings property, can be as health-care nutrient product prolonged application.
The present invention seeks to reach by following prescription, promptly by liquid paraffin as Main Ingredients and Appearance, add glycerol (glycerol) 0～125, sodium chloride 0.9% aqueous solution 6～68.5, acetic acid 1% aqueous solution 3～30, Mel 5～30, vitamin E 0.65～4.50, vitamin A 0.09～0.44, vitamin D3 0.00078～0.00370.
Purpose of the present invention can reach by following measure: with above-mentioned load weighted vitamin E, and A, D3 adds in the quantitative liquid paraffin, stirs up and down to stir to make it even; In addition Mel solution is dissolved in sodium chloride solution, adds glycerol (glycerol) and acetum again, after stirring, join among the liquid paraffin system; Fully behind the mix homogeneously, the solution for preparing is cooled off through moist hear heat test packing sterilization.
Should follow following principle when preparing this preparation: the weight of (1) acetic acid 1% solution is no more than 10% of solution total amount, and the weight of Mel is no more than 10% of solution total amount.When (2) using glycerol (glycerol) in preparation, the consumption (weight) of sodium chloride 0.9% solution is 35～55% of an amounts of glycerol.(3) the solution pH value is 4～4.5.
Adopt following prescription can reach purpose of the present invention preferably:
1. liquid paraffin, 100 weight portions (below the unit of omitting) of filling a prescription, sodium chloride 0.9% aqueous solution 6～8, acetic acid 1% aqueous solution 6～8, Mel 6～8, vitamin E 0.6～0.8, vitamin A 0.09～0.15, vitamin D3 0.0008～0.001.
Prescription 2: liquid paraffin 100 weight portions (below the unit of omitting), glycerol 110～125, sodium chloride 0.9% aqueous solution 38.5～68.5, Mel 15～30, acetic acid 1% aqueous solution 12～30, vitamin E 3～4.5, vitamin A 0.25～0.44, vitamin D3 0.0015～0.0037.
The present invention is used for body's vulva, is to be used for very sensitive part, though be external, mucocutaneously still can partially absorb, therefore, and must be very prudent to the selection of pharmaceutical formulation, requiring must be strict, requires to accomplish:
1. do not have the class medicine of swashing in the preparation, to local epithelium nonirritant, prolonged application is nontoxic, and is harmless, has no side effect;
2. can sufficient lubrication pudendum and vagina, increase comfort, pleasant sensation can play the effect of nourishing healthy again;
3.PH value is suitable, is faintly acid, helps the control of vagina health care and disease;
4. for ease of using, preparation should be free from extraneous odour, and viscosity is suitable, does not pollute skin, and medicated clothing is convenient to the liquid that is coated with exhibition and washs;
5. can long term store, aseptic, efficacy stability is lasting.
The inventor is through long term test, and repeated screening and several years clinical practice grope to test successfully the lubricant that meets requirement of the present invention finally, cause is specially in the nourishing healthy articles for use of " sexual life ", get its partials and be called " fragrant Xerox ", the character of all compositions in now will filling a prescription, description of use is as follows:
One. liquid paraffin: medical cathartic is used for the treatment of constipation and prevention of postoperative difficult defecation.Using it in this preparation mainly is to utilize its lubricious effect to make skin soft and moist.On the other hand, it is to thermally-stabilised, and viscosity is suitable, and diffusibility is good, and incompatibility is few, and is non-stimulated to the part, do not absorb, and is attached to mucocutaneously, and it is local that contained drug is detained, and plays prolongation of effect.In addition, it is easy to washing, not pollution clothes.
But liquid paraffin has slight water sorption, in addition life-time service can hinder fatsoluble vitamin (A, D, E, K) and calcium, the absorption of phosphorus.For overcoming above-mentioned 2 deficiencies, in preparation, add suitable quantity of water, and adapted vitamin medicaments; Simultaneously, use this agent night just before going to bed and can reduce side effect.
Two. rope E supports one's family: can strengthen sexual organ's vigor, delay the gonad atrophy, can protect dermal layer of the skin, improve skin elasticity; Can anti-cancer and cancer-preventing, postpone cell ageing, it is to thermally-stabilised, but with vitamin A and with reinforced effects.It is for utilizing its above-mentioned rare advantage that this preparation adopts vitamin E one, the 2nd, and for remedying the deficiency of aforementioned liquids paraffin.
Three. vitamin A: be the conditioner of skin epidermis, can keep the normal function of mucosa and epithelial tissue, strengthen skin resistance, raise immunity, and health invigorating is arranged, help calcium, the effect that phosphorus absorbs, vitamin A is used in this agent, and purpose is for bringing into play its beneficial functions for skin, in addition, because of the vitamin E Wheat Protein, easily oxidized when vitamin A is heated, therefore, with vitamin E and usefulness, just can be comparatively stable during heating; In addition, vitimin supplement A also can remedy the weak point of liquid paraffin.
The positive usual amounts of vitamin A is ius every days 2000～25000 (5000 ius dimension A is equivalent to 3 milligrams), surpass 100 million international units as dose and use 10 million international units continuously, can cause poisoning, the consumption that this preparation adopts is equivalent to be perfectly safe about 2500 iu/days.
Four. vitamin D3: have the calcium of promotion phosphorus to absorb, regulate alcium and phosphor metabolization, constitutional effect; Its character is more stable, can be stored for a long time and never degenerate.Add micro-vitamin D3 in this preparation, can remedy the deficiency of liquid paraffin, useful body-building health (vitamin D3 1 million international units is 0.25 milligram).
Five. Mel: the tonic that is a kind of life lengthening; Be called as " friend of human beings'health "; Mel contains a large amount of vitamin and aminoacid, and nourishing is arranged, and moisturizes, escherichia coli, Bacillus typhi can be killed and suppress to Detoxication, pathogen growth such as streptococcus, evidence: dysentery bacterium and pyococcus place 5% mulse, stop action in 5 minutes, promptly are killed in 20 minutes, Mel and general medicine Fails To Respond, also possess reproducibility, this preparation can prevent the oxidation deterioration of some drugs with itself and other medicines and usefulness.This preparation uses Mel, is to have scientific value, the innovation of practical value (notes), and middle aged and aged women skin of vulva drying follows the string, and often uses Mel, and it is soft that skin of vulva is moistened; Mel and acetic acid share, and can produce synergy, and it is anticorrosion to sterilize, but the Mel consumption can not surpass 10% of total amount, otherwise human body is had stimulation.Annotate: only finding in a kind of compound glossy ganoderma nutrient cream and make additive with 3% Mel, but should frost different fully with effect of the present invention, be to be used for brothers, and face is prevented being chapped from the cold.
Six. sodium chloride (0.9% aqueous solution): keep the normal osmotic pressure of body fluid, be beneficial to absorption.In this preparation, also be used as solvent, diluent.
Seven. acetic acid (1% aqueous solution): be disinfection preservative, convergence is arranged, antiinflammatory and refreshment effect can suppress antibacterial, and be particularly responsive to bacillus pyocyaneus, and can promote body immunity.Use acetic acid among the present invention except that These characteristics, also because its to thermally-stabilised, anticorrosion.Main is to utilize its acidity, and solution is transferred to suitable pH value (4～4.5).The consumption of acetic acid can not surpass 10% of solution total amount, many Diazolidinyl Urea mucosas.
Eight. glycerol (glycerol): water absorption is arranged, have the liquid of vicidity of sweet taste,, have many uses in medicine and the daily life, can produce, also can produce by vegetable and animals oils by synthetic method in industry.Glycerol has moist, and is anticorrosion and prolong the effect of drug effect, and because of it has wettability, it is local that medicine is detained, and makes lasting medicine.This preparation is the external nutrient that is used for pudendum part skin, uses glycerol as Mucocutaneous protective agent and lubricant, and effect is better.Because it has water absorption, so will add water in the prescription of glycerol, is about half of its consumption.
Because the present invention organically combines above-mentioned all compositions by scientific matching, makes its strong point be cooperated performance, that is short to grow benefit with this, and synergy is remarkable, has play a part positive for finishing task of the present invention.
Preparation provided by the present invention, its preparation method are very simple and easy to do, can divide for three steps carried out, and the first step with all kinds of load weighted vitamin, is dissolved in liquid paraffin, with agitator (available electronic stirring etc.) solution is stirred up and down, stirs; Second step dissolved Mel with sodium chloride solution, added and poured in the liquid paraffin solution after glycerol and acetum stir, the common stirring; The 3rd step was to carry out disinfection with moist hear heat test, required identical with the injecting drug use sterilization.Available circulation steam (100 degrees centigrade) sterilization 30 minutes, also available other modes.
The use of this preparation is advisable with 2 milliliters at every turn, because amount does not reach less and should produce effect, amount is many once toos many or too much for use, easily contaminated.Use the bottle packing, 2 milliliters every bottle, hygienic and convenient.This agent is a liquid dosage form, smears during for ease of use, the most handy plastic jar packing, and 3 milliliters of left and right sides volumes get final product, and leave the space after solution installs and are convenient to shake up; The bottle bottle cap requires sealing closely, takes off bottle cap, and bottleneck is equipped with narrow meshed smooth " mushroom eats head ", and medicinal liquid drip not applied certain pressure with hands and just can flow out when bottle was inverted, and hands pinches bottle and directly smears around vaginal orifice and get final product during use.
The present invention has many advantages, and is much all superior with other cosmetics that are used for skin compared with other lubricant that is used for pudendum, and existing division is as follows:
Be used for the lubricant such as the glycerol of pudendum compared with other, Oleum sesami comes, and this preparation viscosity is suitable, and the diffusibility of height is arranged, and lubricious degree spreads upon the pudendum position well, can play the effect that lubricated vagina replaces vaginal secretions just enter vagina with penis during sexual intercourse; This preparation pH value is 4.5, is weak acid environment, is suitable for intravaginal and suppresses pathogenic bacteria.Thereby help the perineum part health care; And each component of this preparation is all to the skin nonirritant, and its nutrition health-care functions is respectively arranged; Do not pollute skin, medicated clothing is convenient to be coated with exhibition, and hygienic and convenient is used in washing, is convenient to long preservation.Force vagina more dry and astringent compared with the water absorption of glycerol, lubricious deficiency, Oleum sesami, vaseline is thickness too, and shortcomings such as the difficult washing of pollution clothes are come, and its superior part of preparation provided by the present invention is conspicuous.And this preparation is with low cost, and is harmless, is easy to be accepted by people.
Be used for otherwise cosmetics for skin, because lubricity is not as this product, to Mucocutaneous zest than reasons such as this product are big, the general adaptable cosmetics of skin, mucocutaneous differing adapts to (because of its mucosa absorption is strong, responsive especially) surely, all is unsuitable for being applied to the pudendum position, therefore, this product can be described as irreplaceable.
Because it is soft that preparation provided by the present invention can make skin of vulva moisten, elasticity strengthens, sexual function also there is regulating action, overcome the woman vagina secretion and reduced the misery that is caused, thereby alleviate and even eliminate the fear of women to sexual life, the psychology of detest makes sexual life satisfactory more smoothly, harmonious happy, therefore obtained beyond thought promising result.
Introduce some embodiment of the present invention below.
Embodiment 1: prescription: liquid paraffin 100 grams, sodium chloride 0.9% aqueous solution 6 grams, acetic acid 1% aqueous solution 3 grams, Mel 5 grams, vitamin E 0.60 gram, vitamin A 0.09 gram, vitamin D3 0.00078 gram.
Preparation method: take by weighing 600 milligrams of vitamin Es, 90 milligrams of vitamin A (being equivalent to 15 million international units), 0.78 milligram of vitamin D3 (being equivalent to 31.2 million international units).Measure 125 milliliters of liquid paraffin (proportion is about 0.8 gram/cubic centimetre) (100 gram), all vitamin are added in the liquid paraffin, lucifuge, use electronic stirring, oil solution is stirred up and down, until evenly, other gets 5.2 milliliters of Mel (proportion 0.96 gram/cubic centimetre) (5 gram), be dissolved in 6 milliliters of sodium chloride 0.9% solution (proportion 31 gram/cubic centimetres), add 3 milliliters of acetic acid 1% solution (proportion is 1 gram/cubic centimetre) that prepare with distilled water again, stir jointly.This liquid pH value is 4.0.Dress up the bottle of 2 milliliters of potions, then with circulation steam disinfection 30 minutes (packing available aluminium foil clad).
Embodiment 2: liquid paraffin 100 grams (125 milliliters), sodium chloride 0.9% aqueous solution 68.5 grams (68.5 milliliters), glycerol (glycerol) 125 grams (99 milliliters), acetic acid 1% aqueous solution 30 grams (30 milliliters), Mel 30 grams (31.2 milliliters), vitamin E 4.5 grams, vitamin A 0.44 gram (73.3 million international units), vitamin D3 0.0037 gram (148 million international units).
Preparation method: the first step is dissolved in liquid paraffin with vitamin and stirs, and second step was dissolved in sodium chloride solution with Mel, added acetic acid again and glycerol stirs jointly, pH value 4.5.Two kinds of solution mix stirring then, packing, sterilization.
Embodiment 3:
Liquid paraffin 100 grams, glycerol (glycerol) 50 grams, sodium chloride 0.9% aqueous solution 25 grams, acetic acid 1% aqueous solution 25 grams, Mel 20 grams, vitamin E2 gram, vitamin A 0.25 gram, vitamin D3 0.0018 gram.
Preparation method such as embodiment 2.Solution pH value 4.25.
Embodiment 4-9, preparation method is respectively with example 1 or 2.Fill a prescription following (title is respectively with paraffin, salt, acid, honey, E, A, D3, the glycerol representative, unit is gram):
Order component paraffin glycerinate honey E A D3 solution pH value
4 100 0 6 6 6 0.6 0.09 0.0008 4.10
5 100 0 7 7.2 6.8 0.7 0.12 0.0009 4.15
6 100 0 8 8 8 0.8 0.15 0.001 4.20
7 100 110 38.5 12 15 3 0.25 0.0015 4.22
8 100 116 58 12 21 3.8 0.34 0.0022 4.40
9 100 120 48 15 17 1.5 0.25 0.0018 4.30
These several embodiment have finished task proposed by the invention preferably, wherein, are most preferred embodiment with embodiment 4.5.9.
Claims (5)
1, a kind of vaginal lubricant that is used for body's vulva is characterized in that with the liquid paraffin being Main Ingredients and Appearance, and interpolation glycerol (glycerol), vitamin A, vitamin E, Mel, sodium-chloride water solution and aqueous acetic acid are mixed with and form.
2, a kind of method for preparing the described lubricant of claim 1, it is characterized in that its set of dispense ratio is: liquid paraffin 100 weight portions (below the unit of omitting), glycerol (glycerol) 0-125, sodium chloride 0.9% aqueous solution 6～68.5, acetic acid 1% aqueous solution 3～30, Mel 5～30, vitamin E 0.60～4.5, vitamin A 0.09～0.44, compound method is:
2.1 with load weighted vitamin E, A adds in the quantitative liquid paraffin, stirs up and down to stir;
2.2 Mel is dissolved in sodium chloride solution, add glycerol and acetum again, after stirring, be added to liquid paraffin solution;
2.3 abundant mixed solution is sterilized through moist hear heat test.
3, as the method for manufacturing lubricant as described in the claim 2, the weight of acetic acid 1% solution and Mel is all at below 10% of solution total amount when it is characterized in that obtain solution; When using glycerol (glycerol), the consumption of sodium chloride 0.9% solution is the 35-55% of amounts of glycerol; The solution pH value is 4～4.5.
4, as the method for manufacturing lubricant as described in the claim 2, it is characterized in that preparing its ratio of component and be: liquid paraffin 100 weight portions (below the unit of omitting), sodium chloride 0.9% aqueous solution 6～8, acetic acid 1% aqueous solution 6～8, Mel 6～8, vitamin E 0.6～0.8, vitamin A 0.09～0.15.
5, as the method for manufacturing lubricant as described in the claim 3, be characterised in that its component is: liquid paraffin 100 weight portions (below the unit of omitting), sodium-chloride water solution 38.5～68.5, acetic acid 1% aqueous solution 12～30, glycerol (glycerol) 110～125, Mel 15～30, vitamin E 3～4.5, vitamin A 0.25～0.44.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89105335 CN1029456C (en) | 1989-07-28 | 1989-07-28 | Vaginal lubricant for vulva and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 89105335 CN1029456C (en) | 1989-07-28 | 1989-07-28 | Vaginal lubricant for vulva and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1048978A true CN1048978A (en) | 1991-02-06 |
| CN1029456C CN1029456C (en) | 1995-08-09 |
Family
ID=4856099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 89105335 Expired - Fee Related CN1029456C (en) | 1989-07-28 | 1989-07-28 | Vaginal lubricant for vulva and its preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1029456C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2717693A1 (en) * | 1994-03-28 | 1995-09-29 | Tsoutsis Constantin | Fluid gel for vaginal use |
| CN104918625A (en) * | 2012-11-13 | 2015-09-16 | 阿波卡-阿格里科拉共同股份公司 | Enema |
| CN109700897A (en) * | 2019-02-14 | 2019-05-03 | 重庆市洲仨科技发展有限公司 | A kind of female health external application Essence |
| CN111588723A (en) * | 2020-05-22 | 2020-08-28 | 武汉大学 | A kind of gynecological disinfectant and preparation method thereof |
| EP3854382A1 (en) * | 2015-06-01 | 2021-07-28 | Durga Enterprises, LLC | Compositions for treatment of atrophic vaginitis, peri-and postmenopausal dyspareunia, and/or oophorectomized females and treatment methods therewith |
-
1989
- 1989-07-28 CN CN 89105335 patent/CN1029456C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2717693A1 (en) * | 1994-03-28 | 1995-09-29 | Tsoutsis Constantin | Fluid gel for vaginal use |
| CN104918625A (en) * | 2012-11-13 | 2015-09-16 | 阿波卡-阿格里科拉共同股份公司 | Enema |
| CN104918625B (en) * | 2012-11-13 | 2021-07-13 | 阿波卡-阿格里科拉共同股份公司 | Enema |
| EP3854382A1 (en) * | 2015-06-01 | 2021-07-28 | Durga Enterprises, LLC | Compositions for treatment of atrophic vaginitis, peri-and postmenopausal dyspareunia, and/or oophorectomized females and treatment methods therewith |
| CN109700897A (en) * | 2019-02-14 | 2019-05-03 | 重庆市洲仨科技发展有限公司 | A kind of female health external application Essence |
| CN111588723A (en) * | 2020-05-22 | 2020-08-28 | 武汉大学 | A kind of gynecological disinfectant and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1029456C (en) | 1995-08-09 |
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