CN104888243A - Sterile filter online sterilization device and method - Google Patents
Sterile filter online sterilization device and method Download PDFInfo
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- CN104888243A CN104888243A CN201510248189.0A CN201510248189A CN104888243A CN 104888243 A CN104888243 A CN 104888243A CN 201510248189 A CN201510248189 A CN 201510248189A CN 104888243 A CN104888243 A CN 104888243A
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Abstract
The invention discloses a sterile filter online sterilization device and method. The device includes a saturated steam introduction pipeline communicated with the filter front end and a compressed air introduction pipeline communicated with the filter rear end. The saturated steam introduction pipeline is provided with a saturated steam pneumatic valve, the saturated steam introduction pipeline between the saturated steam pneumatic valve and the filter front end is also connected to a front end condensate water discharge pipe, the front end condensate water discharge pipe is also equipped with a front end condensate water discharge pneumatic valve, the compressed air introduction pipeline is equipped with a compressed air pneumatic valve, the compressed air introduction pipeline between the compressed air pneumatic valve and the filter rear end is in connection with a rear end condensate water discharge pipe, and the rear end condensate water discharge pipe is equipped with a rear end condensate water discharge pneumatic valve. The online sterilization method adopts the device. The sterile filter online sterilization device and method provided by the invention have the characteristics of simplicity and practicability, no secondary pollution risk, and thorough sterilization, etc.
Description
Technical field
The present invention relates to pharmaceutical production equipment, particularly relate to the online bactericidal unit of a kind of sterilizing filter and method.
Background technology
The sterilizing of current sterilizing cabinet compressed air sterilizing filter has off-line sterilizing and online sterilizing two kinds of methods usually: adopt off-line sterilization technology, sterilizing is carried out under the operating mode that off-line sterilizing normally can not work at equipment, the filter element of filter need be needed first to be taken apart by filter housing, then filter element is taken off, taken away by the filter element taken off sterilizing-drying process, the filter element after sterilizing reinstalls in filter filter housing; Sterilization treatment is carried out in online forward sterilizing before this automatic being led to by saturated vapor in filter, and carry out online dry process to filter filter housing, filter element and sterilizing pipeline after sterilizing, saturated vapor makes consistent with compressed air through the direction of filter.
All there is certain deficiency in above-mentioned two kinds of methods: the pipeline sterilizing that filter housing can not be connected with sterilizing cabinet cavity with filter by off-line sterilizing, and the filter element after sterilizing reinstalls to the risk having secondary pollution in the process of filter housing.Off-line steam sterilization steam does not circulate filter element, the removing residues such as the bacterium corpse remained on filter element and particulate matter can not be fallen, therefore exist off-line sterilization time length, inconvenient operation, sterilizing cost high, connect filter pipes and there is no the defects such as sterilizing; And online forward sterilizing due to saturated vapor and compressed air be consistent through the direction of filter, when the polluter such as antibacterial and particulate matter is by filter, polluter is intercepted outside by the filter element of filter, not by filter element, when saturated vapor carries out online sterilizing to filter, the polluter such as bacterium corpse and granule, still not by filter element, remain on the filter element of filter, affect the filter effect of filter, the easy breed bacteria of residue.
Summary of the invention
The technical problem to be solved in the present invention overcomes the deficiencies in the prior art, provides a kind of simple, non-secondary pollution risk and the sterilizing online bactericidal unit of sterilizing filter and method thoroughly.
For solving the problems of the technologies described above, the present invention by the following technical solutions:
The online bactericidal unit of a kind of sterilizing filter, comprise the saturated vapor be connected with described filter front and pass into pipeline and the compressed air that is connected with described filter rear end passes into pipeline, described saturated vapor passes into pipeline and is provided with saturated vapor pneumatic operated valve, saturated vapor between described saturated vapor pneumatic operated valve and described filter front passes into and pipeline is also connected with front end arranges drip pipe, described front end row's drip pipe is provided with front end row's condensed water pneumatic operated valve, described compressed air passes into pipeline and is provided with compressed air pneumatic operated valve, compressed air between described compressed air pneumatic operated valve and described filter rear end passes into and pipeline is connected with rear end arranges drip pipe, described rear end row's drip pipe is provided with rear end row's condensed water pneumatic operated valve.
Further improvement as technique scheme:
Described saturated vapor passes into pipeline and is provided with pressure transducer and current limliting joint.
The online sterilizing methods of a kind of sterilizing filter, comprises the following steps:
S1, open front end row's condensed water pneumatic operated valve and rear end row's condensed water pneumatic operated valve;
S2, open saturated vapor pneumatic operated valve, pass into saturated vapor from filter front, when reaching setting value to sterilising temp, start timing sterilizing, to setting-up time, close saturated vapor pneumatic operated valve;
S3, open compressed air pneumatic operated valve, pass into compressed air from filter rear end, after being cooled to room temperature to setting-up time or filter, closes compression air pneumatic operated valve;
S4, when being zero to pressure in filter, closed front end row's condensed water pneumatic operated valve and rear end row's condensed water pneumatic operated valve.
Further improvement as technique scheme:
In step s 2, by the pressure of saturated vapor in pressure transducer and current limliting joint controlling filter.
Compared with prior art, the invention has the advantages that:
(1) the online bactericidal unit of sterilizing filter of the present invention, compressed air is passed into pipeline and be arranged on filter rear end, saturated vapor passes into pipeline and is arranged on filter rear end, first pass into saturated vapor and the online sterilizing of forward is carried out to filter, pass into compressed air subsequently and carry out reverse cleaning, can oppositely oppositely be flushed to passing into the pollutant such as bacterium corpse, particulate matter sticked on filter element when saturated vapor carries out sterilizing in condensed water, through front end, row's drip pipe is drained, can not remain in filter, make the cleaning sterilizing of filter more thorough.
(2) the online sterilizing methods of sterilizing filter of the present invention, first front end row's condensed water pneumatic operated valve and rear end row's condensed water pneumatic operated valve is opened, open saturated vapor pneumatic operated valve subsequently, saturated vapor is passed into from filter front, because front end row's condensed water pneumatic operated valve is opening, the front end condensed water that saturated vapor produces before entering filter is drained through front end row's condensed water pneumatic operated valve, can ensure to enter filter carry out cleaning sterilizing for saturated vapor, when reaching setting value to sterilising temp, start timing sterilizing, to setting-up time, close saturated vapor pneumatic operated valve, open compressed air pneumatic operated valve again, compressed air is passed into from filter rear end, purged by compressed air and residual condensed water is drained through front end row's condensate pipe and rear end row's condensate pipe, the compressed-air actuated purging of remaining gentleness of filter and pipeline is utilized to carry out drying to filter element, closes compression air pneumatic operated valve to setting-up time or filter cool to room temperature, sterilizing completes, when in device to be filtered, pressure reduces to zero, closed front end row's condensed water pneumatic operated valve and rear end row's condensed water pneumatic operated valve, namely whole online sterilization process is completed, the online sterilizing methods of sterilizing filter of the present invention, the online sterilizing to filter can be realized, secondary pollution risk can not be produced, and disinfecting action is simple and convenient, compressed air is passed into from filter rear end, oppositely can will pass into the bacterium corpse sticked to when saturated vapor carries out sterilizing on filter element, the pollutant such as particulate matter are oppositely flushed in condensed water, through front end, row's drip pipe is drained, can not remain in filter, make the cleaning sterilizing of filter more thorough.
Accompanying drawing explanation
Fig. 1 is the structural representation of the online bactericidal unit that the online sterilizing methods of sterilizing filter of the present invention adopts.
In figure, each label represents:
1, front end row condensed water pneumatic operated valve; 2, rear end row condensed water pneumatic operated valve; 3, saturated vapor pneumatic operated valve; 4, compressed air pneumatic operated valve; 5, filter; 6, pressure transducer; 7, current limliting joint.
Detailed description of the invention
Below with reference to Figure of description and specific embodiment, the present invention is described in further details.
Fig. 1 shows the structural representation of the online bactericidal unit of sterilizing filter of the present invention, the online bactericidal unit of this sterilizing filter comprises the saturated vapor be connected with filter 5 front end and passes into pipeline and the compressed air that is connected with filter 5 rear end passes into pipeline, saturated vapor passes into pipeline and is provided with saturated vapor pneumatic operated valve 3, saturated vapor between saturated vapor pneumatic operated valve 3 and filter 5 front end passes into and pipeline is also connected with front end arranges drip pipe, front end row's drip pipe is provided with front end row's condensed water pneumatic operated valve 1, compressed air passes into pipeline and is provided with compressed air pneumatic operated valve 4, compressed air between compressed air pneumatic operated valve 4 and filter 5 rear end passes into and pipeline is connected with rear end arranges drip pipe, rear end row's drip pipe is provided with rear end row's condensed water pneumatic operated valve 2, compressed air is passed into pipeline and be arranged on filter 5 rear end, saturated vapor passes into pipeline and is arranged on filter 5 rear end, first open saturated vapor pneumatic operated valve 3 to pass into saturated vapor and carry out the online sterilizing of forward to filter 5, the condensed water produced is discharged by rear end row's drip pipe, open saturated vapor pneumatic operated valve 3 subsequently to pass into compressed air and carry out reverse cleaning, oppositely can will pass into the bacterium corpse sticked to when saturated vapor carries out sterilizing on filter 5 filter element, the pollutant such as particulate matter are oppositely flushed in condensed water, through front end, row's drip pipe is drained, can not remain in filter 5, make the cleaning sterilizing of filter 5 more thorough.
In the present embodiment, saturated vapor passes into pipeline and is provided with pressure transducer 6 and current limliting joint 7, the pressure of saturated vapor in controlling filter 5.
The online sterilizing methods of sterilizing filter of the present invention, specifically comprises the following steps:
S1, open front end row's condensed water pneumatic operated valve 1 and rear end row's condensed water pneumatic operated valve 2;
S2, open saturated vapor pneumatic operated valve 3, pass into saturated vapor from filter 5 front end, when reaching setting value to sterilising temp, start timing sterilizing, to setting-up time, close saturated vapor pneumatic operated valve 3;
S3, open compressed air pneumatic operated valve 4, pass into compressed air from filter 5 rear end, after being cooled to room temperature to setting-up time or filter 5, closes compression air pneumatic operated valve 4;
S4, when being zero to pressure in filter 5, closed front end row condensed water pneumatic operated valve 1 and rear end row's condensed water pneumatic operated valve 2.
Before the online sterilizing of beginning, front end row's condensed water pneumatic operated valve 1, rear end row's condensed water pneumatic operated valve 2, saturated vapor pneumatic operated valve 3 and compressed air pneumatic operated valve 4 are closed condition, first front end row's condensed water pneumatic operated valve 1 and rear end row's condensed water pneumatic operated valve 2 is opened, open saturated vapor pneumatic operated valve 3 subsequently, saturated vapor is passed into from filter 5 front end, because front end row's condensed water pneumatic operated valve 1 is opening, the front end condensed water that saturated vapor produces before entering filter 5 is drained through front end row's condensed water pneumatic operated valve 1, can ensure to enter filter 5 carry out cleaning sterilizing for saturated vapor, when reaching setting value to sterilising temp, start timing sterilizing, to setting-up time, close saturated vapor pneumatic operated valve 3, open compressed air pneumatic operated valve 4 again, compressed air is passed into from filter 5 rear end, purged by compressed air and residual condensed water is drained through front end row's condensate pipe and rear end row's condensate pipe, the compressed-air actuated purging of remaining gentleness of filter 5 and pipeline is utilized to carry out drying to filter element, closes compression air pneumatic operated valve 4 to setting-up time or filter 5 cool to room temperature, sterilizing completes, when in device 5 to be filtered, pressure reduces to zero, closed front end row condensed water pneumatic operated valve 1 and rear end row's condensed water pneumatic operated valve 2, namely complete whole online sterilization process.
The online sterilizing methods of sterilizing filter of the present invention, the online sterilizing to filter 5 can be realized, secondary pollution risk can not be produced, and disinfecting action is simple and convenient, passing into compressed air from filter 5 rear end, being oppositely oppositely flushed to passing into the pollutant such as bacterium corpse, particulate matter sticked on filter 5 filter element when saturated vapor carries out sterilizing in condensed water, through front end, row's drip pipe is drained, can not remain in filter 5, make the cleaning sterilizing of filter 5 more thorough.
In step s 2, by the pressure of saturated vapor in pressure transducer 6 and current limliting joint 7 controlling filter 5.
In the present invention, the setting-up time of timing sterilizing and dry setting-up time is carried out to filter element all can preset in advance.
Although the present invention discloses as above with preferred embodiment, but and be not used to limit the present invention.Any those of ordinary skill in the art, when not departing from technical solution of the present invention scope, can utilize the technology contents of above-mentioned announcement to make many possible variations and modification to technical solution of the present invention, or being revised as the Equivalent embodiments of equivalent variations.Therefore, every content not departing from technical solution of the present invention, according to the technology of the present invention essence to any simple modification made for any of the above embodiments, equivalent variations and modification, all should drop in the scope of technical solution of the present invention protection.
Claims (4)
1. the online bactericidal unit of sterilizing filter, it is characterized in that: comprise the saturated vapor be connected with described filter (5) front end and pass into pipeline and the compressed air that is connected with described filter (5) rear end passes into pipeline, described saturated vapor passes into pipeline and is provided with saturated vapor pneumatic operated valve (3), saturated vapor between described saturated vapor pneumatic operated valve (3) and described filter (5) front end passes into and pipeline is also connected with front end arranges drip pipe, described front end row's drip pipe is provided with front end row's condensed water pneumatic operated valve (1), described compressed air passes into pipeline and is provided with compressed air pneumatic operated valve (4), compressed air between described compressed air pneumatic operated valve (4) and described filter (5) rear end passes into and pipeline is connected with rear end arranges drip pipe, described rear end row's drip pipe is provided with rear end row's condensed water pneumatic operated valve (2).
2. the online bactericidal unit of sterilizing filter according to claim 1, is characterized in that: described saturated vapor passes into pipeline and is provided with pressure transducer (6) and current limliting joint (7).
3. the online sterilizing methods of sterilizing filter, is characterized in that, comprise the following steps:
S1, open front end row condensed water pneumatic operated valve (1) and rear end arrange condensed water pneumatic operated valve (2);
S2, open saturated vapor pneumatic operated valve (3), pass into saturated vapor from filter (5) front end, when reaching setting value to sterilising temp, start timing sterilizing, to setting-up time, close saturated vapor pneumatic operated valve (3);
S3, open compressed air pneumatic operated valve (4), pass into compressed air from filter (5) rear end, after being cooled to room temperature to setting-up time or filter (5), closes compression air pneumatic operated valve (4);
S4, when being zero to filter (5) interior pressure, condensed water pneumatic operated valve (2) is arranged in closed front end row's condensed water pneumatic operated valve (1) and rear end.
4. the online sterilizing methods of sterilizing filter according to claim 3, is characterized in that: in step s 2, by the pressure of saturated vapor in pressure transducer (6) and current limliting joint (7) controlling filter (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510248189.0A CN104888243A (en) | 2015-05-15 | 2015-05-15 | Sterile filter online sterilization device and method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510248189.0A CN104888243A (en) | 2015-05-15 | 2015-05-15 | Sterile filter online sterilization device and method |
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| CN104888243A true CN104888243A (en) | 2015-09-09 |
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| CN201510248189.0A Pending CN104888243A (en) | 2015-05-15 | 2015-05-15 | Sterile filter online sterilization device and method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111167223A (en) * | 2019-12-31 | 2020-05-19 | 北京牵手果蔬饮品股份有限公司 | Sterile air filtering device |
| CN111281989A (en) * | 2020-03-31 | 2020-06-16 | 冰山松洋生物科技(大连)有限公司 | Vertical pressure steam sterilizer with safety exhaust function |
| CN112516340A (en) * | 2020-12-15 | 2021-03-19 | 江苏新美星包装机械股份有限公司 | Steam sterilization method for instrument pipeline in filling equipment |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101690824A (en) * | 2009-10-12 | 2010-04-07 | 张家港市华菱医疗设备制造有限公司 | On-line sterilizer of damp and hot vapour sterilization cabinet |
-
2015
- 2015-05-15 CN CN201510248189.0A patent/CN104888243A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101690824A (en) * | 2009-10-12 | 2010-04-07 | 张家港市华菱医疗设备制造有限公司 | On-line sterilizer of damp and hot vapour sterilization cabinet |
Non-Patent Citations (1)
| Title |
|---|
| 姚菊英，臧丽坤，冯志刚: "《化工单元过程分析与进展研究》", 30 June 2014 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111167223A (en) * | 2019-12-31 | 2020-05-19 | 北京牵手果蔬饮品股份有限公司 | Sterile air filtering device |
| CN111281989A (en) * | 2020-03-31 | 2020-06-16 | 冰山松洋生物科技(大连)有限公司 | Vertical pressure steam sterilizer with safety exhaust function |
| CN112516340A (en) * | 2020-12-15 | 2021-03-19 | 江苏新美星包装机械股份有限公司 | Steam sterilization method for instrument pipeline in filling equipment |
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Application publication date: 20150909 |
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