CN104886045A - Paraquat effervescent granule and preparation method thereof - Google Patents
Paraquat effervescent granule and preparation method thereof Download PDFInfo
- Publication number
- CN104886045A CN104886045A CN201510190807.0A CN201510190807A CN104886045A CN 104886045 A CN104886045 A CN 104886045A CN 201510190807 A CN201510190807 A CN 201510190807A CN 104886045 A CN104886045 A CN 104886045A
- Authority
- CN
- China
- Prior art keywords
- paraquat
- effervescent
- acid
- parts
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention belongs to the field of pesticide agents, and relates to a weed killer, particularly to a paraquat effervescent granule and a preparation method thereof, wherein the paraquat effervescent granule comprises, by weight, 5-80 parts of paraquat, 0.1-20 parts of a dispersant, 0.1-15 parts of a wetting agent, 1-50 parts of a disintegrating agent, 0.1-15 parts of a binder, and 0.1-50 parts of a filler. Compared with the paraquat effervescent granule and the preparation method in the prior art, the paraquat effervescent granule and the preparation method of the present invention have the following advantages and positive effects that: the paraquat agent having the granule dosage form is provided through the new formula, the traditional agent having the water dosage form is changed, and the granule dosage form is difficult to take so as to avoid the life safety problem caused by human taking; with the granule dosage form, the environmental pollution caused by the pesticide liquid residue in the paraquat glue product packaging object can be avoided; and the granule dosage form product has characteristics of easy packaging, easy measurement, easy transportation, easy storage, and safety on human and environment.
Description
Technical field
The invention belongs to pesticidal chemical field, relate to weed killer herbicide, particularly relate to a kind of paraquat effervescent and preparation method thereof.
Background technology
Paraquat, chemical name is 1-1-dimethyl-4-4-bipyridine cation salt, and be a kind of steriland herbicide fast, the photosynthetical system in the chloroplast of green plants absorbs luminous energy and manufactures sugar, thus provides nutrient for plant.Paraquat can accurately enter the biochemical system being referred to as photosynthetical system, this system can produce free electron to promote photosynthesis, paraquat ion and these electronics react and are formed " free radical ", these radical conversions are peroxide rapidly by oxygen, and these peroxide are easy to react with the unsaturated fatty acid in cell membrane, through this series of chemical reaction, cell membrane is destroyed, cellular content leaks and mixes, and causes larger destruction, makes it withered.Whole process is very rapid, the therefore paraquat transfer that can not can observe.And to the not effect of non-green tissue.Simultaneously paraquat is combined and passivation with soil rapidly in soil, to plant root and perennial subterranean stem and perennial root invalid.
Its structural formula:
Molecular formula: C12H14Cl2N2
Chemical name: 1-1-dimethyl-4-4-bipyridine cation salt
Physicochemical property: former medicine is white crystal, content > more than 97%, 300 DEG C decomposition, proportion 1.10, very easily water-soluble, be slightly soluble in low-molecular-weight alcohols, be insoluble to varsol.Stable in acidity and neutral solution, be hydrolyzed in alkalescence.Former medicine is corrosive to metal.
Paraquat preparation is mainly aqua product in the market, because paraquat aqua is after people wrongly takes, without special efficacy antidote, lethality rate reaches 90%, country, for this situation, from 1 day July in 2014, cancels the registration of paraquat aqua and production permit, stop producing, stop aqua selling at home and use on July 1st, 2016.But; due to paraquat site of action accurately and rapidly herbicidal effect and rain fastness energy and contacting with soil lose activity and retain weeds root system, characteristic to crop safety; make paraquat in conservation tillage system especially in no-tillage technology; play crucial and irreplaceable effect; in the use procedure of immediate and mid-term; paraquat is accepted by peasant all over the world; create huge society and economic benefit; also reduce the phenomenon of the soil erosion simultaneously, become indispensable agriculture articles for use.Therefore this researches and develops a kind of paraquat novel form with regard to an urgent demand pesticide industry.
Summary of the invention
The present invention is directed to the safety problem of above-mentioned existing product formulation, provide a kind of and be that former medicine, product are efficient with paraquat, low toxicity, environmentally friendly, and packaging, storing and paraquat effervescent easy to use.
In order to achieve the above object, the technical solution used in the present invention is, a kind of paraquat effervescent, and this paraquat effervescent comprises following composition by weight:
Paraquat 5 parts ~ 80 parts;
Dispersant 0.1 part ~ 20 parts;
Wetting agent 0.1 part ~ 15 parts;
Disintegrant 1 part ~ 50 parts;
Adhesive 0.1 part ~ 15 parts;
Filler 0.1 part ~ 50 parts.
At above-mentioned paraquat effervescent, described dispersant is at least one material in polycarboxylate, di-2-ethylhexylphosphine oxide methyl naphthalene sulfonic acid salt, acrylate copolymer, di-2-ethylhexylphosphine oxide naphthalene sulfonate, lignosulfonates, naphthalenesulfonate formaldehyde condensation compound, Pluronic PE 6800; Preferred dispersant is the combination of dispersing agent MF and lignosulfonates, the combination of naphthalenesulfonate formaldehyde condensation compound and lignosulfonates or only use dispersing agent MF, contrast through test of many times, find that above-mentioned 3 kinds use as dispersant, institute is made into paraquat effervescent best results.
At above-mentioned paraquat effervescent, described wetting agent is at least one material in Nekal BX, ethoxylated dodecyl alcohol sodium sulphate, polyoxyethylene nonylphenol ether, lauryl sodium sulfate, neopelex, nekal, succinic acid dibutyl ester sodium sulfonate, fatty alcohol-polyoxyethylene ether; Preferred wetting agent is lauryl sodium sulfate or neopelex.
At above-mentioned paraquat effervescent, described disintegrant is at least two kinds of materials in urea, potash, calcium carbonate, sodium carbonate, sodium bicarbonate, citric acid, malonic acid, succinic acid, adipic acid, tartaric acid, maleic acid, fumaric acid, benzoic acid, amino acid, potassium dihydrogen phosphate, sorbic acid; Preferred disintegrant is the combination of sodium bicarbonate and citric acid, the combination of sodium carbonate or the combination of sodium bicarbonate and citric acid and sodium carbonate and citric acid.
At above-mentioned paraquat effervescent, described adhesive is at least one material in starch and derivative thereof, dextrin, polyvinyl alcohol, sodium carboxymethylcellulose, hydroxypropyl cellulose, polyethylene glycol, pyrrolidones, gum Arabic; Preferred adhesive is gum Arabic or polyvinyl alcohol or sodium carboxymethylcellulose.
At above-mentioned paraquat effervescent, described filler is at least one material in stearate, precipitated calcium carbonate, talcum powder, bentonite, atlapulgite, White Carbon black, glucose, lactose, sucrose, starch, diatomite, attapulgite, potter's clay, kaolin; Preferred filler is kaolin or attapulgite or talcum powder.
By the concrete test of a large amount of laboratory experiments and experimental field, above-mentioned all kinds of materials, preferred material is for inventing the embodiment of the optimum provided, its best results.
Present invention also offers the preparation method of above-mentioned paraquat effervescent, comprise the following steps:
A, mixing: paraquat, dispersant, wetting agent, disintegrant, filler etc. are mixed and obtains mixture;
B, pulverizing: by mixture through air-flow/ultramicro grinding, obtain female powder;
C, granulation: adhesive and female powder are fully mixed by mixing apparatus, by Granulation Equipments granulating and forming;
D, oven dry: the particle obtained is dried.
As preferably, described step also comprises:
E, screening: the particle of oven dry is screened.
As preferably, mixture is crushed to particle diameter≤10 μm by described step b.
As preferably, described granulation step comprises disc granulation, extruder grain, fluidized granulating, fluidized bed prilling, mist projection granulating or mixed at high speed granulation.
Compared with prior art, advantage of the present invention and good effect are,
1. provided a kind of paraquat medicament of bead dosage form by new formula, change traditional water aqua type medicament, bead dosage form is difficult to swallow simultaneously, avoids the life security problem caused because people is oral; In addition bead dosage form it also avoid paraquat jelly product package material inner liquid medicine and remains the environmental pollution caused; Bead dosage form product is easy to packaging, metering, transport and storage in addition, to the mankind and Environmental security, is the desirable formulation of alternative traditional aqua.
2. the paraquat effervescent produced of this formula water-soluble effective, suspensibility is high, and disintegration rate is fast and heat storage stability is good.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme of the embodiment of the present invention, below the accompanying drawing used required in describing embodiment is briefly described, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
The flow process chart that Fig. 1 provides for the embodiment of the present invention 1.
Embodiment
In order to more clearly understand above-mentioned purpose of the present invention, feature and advantage, below in conjunction with drawings and Examples, the present invention will be further described.It should be noted that, when not conflicting, the feature in the embodiment of the application and embodiment can combine mutually.
Set forth a lot of detail in the following description so that fully understand the present invention, but the present invention can also adopt and be different from other modes described here and implement, and therefore, the present invention is not limited to the restriction of the specific embodiment of prospectus below.
Experimental technique described in following embodiment, if no special instructions, is conventional method; Described reagent and material, if no special instructions, all can obtain from commercial channels; " part " representative " parts by weight " in following embodiment.
Embodiment 1: the formula present embodiments providing one group of concrete paraquat effervescent, in the present embodiment, former medicine and auxiliary agent are selected and proportioning is:
The former medicine of 95% paraquat 5.26 parts;
Dispersing agent MF 2.0 parts, calcium lignosulfonate 4.0 parts;
Lauryl sodium sulfate 2.0 parts;
Sodium bicarbonate 17.0 parts, 4.0 parts, sodium carbonate, citric acid 15.0 parts;
Gum Arabic 3.0 parts;
Attapulgite complements to 100 parts.
Each amounts of components is calculated respectively by above proportioning; weigh; mix; by paraquat, dispersant, wetting agent, disintegrant (acidity or alkaline; because disintegrant divides acidity and alkalescence, therefore sour grain or alkali grain will be produced respectively in subsequent step), filler etc. mixes and obtains mixture.
By the mixture of above-mentioned steps through air-flow/ultramicro grinding, to particle diameter D90≤10 μm, obtain female powder.
The aqueous solution of adhesive and female powder are fully mixed by mixer; shaping by granulator granulation; the mode of granulating and forming has a variety of, in the present embodiment, mainly comprises disc granulation, extruder grain, fluidized granulating, fluidized bed prilling, mist projection granulating and mixed at high speed granulation.
Dry, bake out temperature 82 DEG C-85 DEG C, dry 30-35 minute, it is qualified for detecting moisture≤1.0%.
Sieve selected.To dry after produce sour grain and alkali grain sieve, selected, Control granularity 2mm≤d≤3mm.
Need sour grain, the mixing of alkali grain according to difference, in the present embodiment, sour grain and the ratio mixed of alkali grain are 5:5 (the sour grain mentioned about above content and alkali grain.Acid grain refers to the particle that disintegrant use acidic materials cause as composition; Alkali grain refers to the particle that disintegrant use alkaline matter causes as composition.For avoiding reacting in process of production, sour grain and alkali grain are separately produce, after treating that sour grain and alkali grain are dried respectively in process of production, mix again, mixed effervescent, at dilution with water, just because acid-base reaction, can disperse rapidly, soak.Independent sour grain and alkali grain are difficult to disperse rapidly in water).
Detected by the particle mixed, whether the main indices detecting effervescent is qualified, comprises the indexs such as former medicine content, wetability are qualified, disintegrative, foaming characteristic, moisture, expulsion rate, pH, suspensibility.
Concrete grammar is as follows:
Liquid chromatograph (Japanese Shimadzu Corporation, L-20A) is used to detect active constituent content.Take 1.0 grams of samples and pour the band plug graduated cylinder that 250 milliliters of standard hard water are housed into, the time that record product all departs from liquid level is wetability; Repeatedly put upside down graduated cylinder back and forth, the number of times (or time) of the whole disintegration dispersion of record sample is disintegrative; After putting upside down graduated cylinder 30 times back and forth, leave standstill 30 seconds recording foam volume is afterwards the foaming characteristic of product; Leave standstill after 30 minutes, the dried and clean culture dish of graduated cylinder upper strata 90% bulk solution to the W1 that weighs is removed with vavuum pump, and move to culture dish 3 times with a small amount of standard hard water flushing graduated cylinder, dry to constant weight W2 for 80 DEG C, calculate suspensibility %=(1-(W2-W1)) × 10/9 × 100%.
Take 1.0 grams of samples and pour the band plug graduated cylinder that 100 milliliters of standard hard water are housed into, put upside down 30 times back and forth, measure pH scope with pH meter; Take the effervescent sample of certain mass M1, put into the standard screen (420 μm, aperture) filling 2 steel balls (Φ 30 ± 2) or porcelain ball, sieve is placed on chassis and adds a cover, to move in vibrating machine fixing after to vibrate 15min, accurately take and meet sample mass M2 (being accurate to 0.1g) in dish, expulsion rate %=M2/M1 × 100% of sample.
The sample taking certain mass packs, and places 14 days, carries out active ingredient index evaluation for 54 DEG C, calculates active ingredient heat storage resolution ratio.
Paraquat effervescent performance indications prepared by embodiment 1 are: paraquat content 4.96%, wetability qualified (21 seconds), disintegration (45 seconds), foaming characteristic qualified (16 milliliters), moisture 1.2%, expulsion rate 0.5%, pH value 6.8, suspensibility 100% (former medicine all dissolves), screen analysis 99%, heat storage stability is qualified, active ingredient resolution ratio 1.2%.
Embodiment 2: the formula present embodiments providing one group of 80% paraquat effervescent, in the present embodiment, former medicine and auxiliary agent are selected and proportioning is:
The former medicine of 95% paraquat 84.2 parts;
Naphthalenesulfonate formaldehyde condensation compound 2.5 parts, sodium lignin sulfonate 2.0 parts;
Neopelex 1.5 parts;
2.5 parts, sodium carbonate, citric acid 5.0 parts;
Polyvinyl alcohol 1.0 parts;
Talcum powder complements to 100 parts.
Calculate each amounts of components respectively by above proportioning, weigh, mix; Formulation material is through ultra micro/air-flow crushing granulation, oven dry, granulation, selected.Carry out Product checking according to effervescent tablet quality control index, index includes effective component content, disintegration time limited, suspensibility, foaming characteristic, screen analysis, powder and fragment rate, PH scope and heat storage stability etc.Concrete grammar is as follows:
Liquid chromatograph (Japanese Shimadzu Corporation, L-20A) is used to detect active constituent content.
Take 1.0 grams of samples and pour the band plug graduated cylinder that 250 milliliters of standard hard water are housed into; After putting upside down graduated cylinder 30 times back and forth, leave standstill 30 seconds recording foam volume is afterwards the foaming characteristic of product; Leave standstill after 30 minutes, the dried and clean culture dish of graduated cylinder upper strata 90% bulk solution to the W1 that weighs is removed with vavuum pump, and move to culture dish 3 times with a small amount of standard hard water flushing graduated cylinder, dry to constant weight W2 for 80 DEG C, calculate suspensibility %=(1-(W2-W1)) × 10/9 × 100%.
Take 1.0 grams of samples and pour the band plug graduated cylinder that 100 milliliters of standard hard water are housed into, put upside down 30 times back and forth, measure pH scope with pH meter; Get a slice sample and put into the culture dish (Φ 100mm) filling water, start stopwatch, measure disintegration time limited; Take the effervescent tablet sample of certain mass Q1, collect whole powder and fragment (is no more than tablet quality, be considered as fragment) and accurately claim to obtain quality Q 2 (being accurate to 0.01 gram), the sample that the powder of sample and fragment rate %=Q2/Q1 × 100 take certain mass packs, place 14 days for 54 DEG C, carry out active ingredient index evaluation, calculate active ingredient heat storage resolution ratio.
The each performance indications of paraquat effervescent tablet prepared by embodiment 2: paraquat content 80.5%, wetability qualified (23 seconds) disintegration time limited qualified (54s), foaming characteristic qualified (22 milliliters), expulsion rate 0.3%, moisture 1.2%, pH value 6.4, suspensibility 100%, screen analysis 99%, heat storage stability is qualified, active ingredient resolution ratio 0.5%.
Embodiment 3: the formula present embodiments providing one group of 50% paraquat effervescent, in the present embodiment, former medicine and auxiliary agent are selected and proportioning is:
The former medicine of 95% paraquat 52.63 parts;
Dispersing agent MF 5.0 parts;
Neopelex 3.0 parts;
Alkali grain 8.0 parts, sodium carbonate, sodium bicarbonate 10 parts;
Acid grain citric acid 18 parts;
Sodium carboxymethylcellulose 3.0 parts;
Filler is that kaolin supplies 100 parts.
Concrete preparation process and experiment testing process consistent with embodiment 1, embodiment 2.
Embodiment 3: the assay method of each performance indications of paraquat effervescent of preparation is with embodiment 1.Concrete measurement result is: paraquat content 50.2%, wetability qualified (22 seconds), disintegration qualified (48 seconds), foaming characteristic qualified (24 milliliters), moisture 1.0%, expulsion rate 0.8%, pH value 6.2, suspensibility 100%, screen analysis 99%, heat storage stability is qualified, active ingredient resolution ratio 0.6%.
Three embodiment experimental result contrasts
| Embodiment 1 | Embodiment 2 | Embodiment 3 | |
| Paraquat content | 4.96％ | 80.5％ | 50.2％ |
| Wetability | Qualified (21s) | Qualified (23s) | Qualified (22s) |
| Disintegration | 45s | 54s | 48s |
| Foaming characteristic | Qualified (16ml) | Qualified (22ml) | Qualified (24ml) |
| Moisture | 1.2％ | 1.2％ | 1.0％ |
| Expulsion rate | 0.5％ | 0.3％ | 0.8％ |
| PH value | 6.8 | 6.5 | 6.2 |
| Suspensibility | 100％ | 100％ | 100％ |
| Screen analysis | 99％ | 99％ | 99％ |
| Heat storage stability | Qualified | Qualified | Qualified |
| Active ingredient resolution ratio | 1.2％ | 0.5％ | 0.6％ |
The test of pesticide effectiveness:
Compare to carry out drug effect with paraquat effervescent of the present invention, the 200g/l paraquat aqua (first just reaching Kirchhoff integral) that buying market is most widely used and domestic certain producer 200g/L paraquat aqua (green track) are for activity of weeding check experiment.
Activity of weeding is listed in following each embodiment for the weeds kind of testing postemergence herbicide activity of the present invention.These tests carry out for the weeds of land for growing field crops in all parts of the country self-sow, mainly contains lady's-grass, eleusine indica, the rhizome of nutgrass flatsedge, green foxtail, Horseweed Herb etc.
Test the test method that specifies according to GB/T17980.1-17980.50-2000 " pesticide field efficacy medicine test criterion () " and investigation method is carried out.Each process is according to recommended dose dispenser, and 4 repetitions are established in each process, and each plot area is 45m
2, each community randomized arrangement; In the dispenser of weed growth animated period, water consumption is according to 650L/h m
2calculate; Respectively at after medicine 1,3,5,7,14 day, at each community Stochastic choice 3-4 point, often some 0.5m
2carry out sample investigation, the total strain number of often kind of weeds of record investigation.The average weed density in the front test region of medicine is 1050 strains/m
2, the main ruderal species class lady's-grass in this ground, eleusine indica, the rhizome of nutgrass flatsedge, green foxtail, Horseweed Herb, accounting is classified as 40.2%, 18.5%, 15.2%, 14.3%, 11.8% routine dividing by strain number percentage.Result of the test calculates the drug effect of medicament according to the following equation: control efficiency (%)=(the careless number of the blank district remaining work of careless number-treatment region alive) careless number × 100 alive ,/blank district.
Blank district careless number alive also does once total herbicidal effect investigation for 14 days after administration, adopts eye estimate investigation method.Classification investigation and record.
Weed control efficacy grade scale is as following table:
| Rank | Weeding (grass of living) situation describes |
| 1 grade | Without grass |
| 2 grades | Be equivalent to the 0-2.5% of blank district weeds |
| 3 grades | Be equivalent to the 2.5%-5% of blank district weeds |
| 4 grades | Be equivalent to the 5%-10% of blank district weeds |
| 5 grades | Be equivalent to the 10%-15% of blank district weeds |
| 6 grades | Be equivalent to the 15%-25% of blank district weeds |
| 7 grades | Be equivalent to the 25%-35% of blank district weeds |
| 8 grades | Be equivalent to the 35%-67.5% of blank district weeds |
| 9 grades | Be equivalent to the 67.5%-100% of blank district weeds |
Raw embodiment paraquat effervescent of surveying is tested the herbicidal effect of lady's-grass.
According to test requirements document, after the lady's-grass with the chemicals treatment growth animated period of embodiment and comparative example, the strain preventive effect investigating each process for 1,3,5,7,14 day after the treatment respectively, its result of the test is in table one.
Table one embodiment and comparative example are to the control efficiency (%) of lady's-grass
Can find out according to data in table, this paraquat effervescent first reaches Kirchhoff integral compare with green track with contrast, is better than comparison example or difference is not remarkable to the preventive effect of lady's-grass.
Raw embodiment paraquat effervescent of surveying is tested the herbicidal effect of eleusine indica.
According to test requirements document, after the eleusine indica with the chemicals treatment growth animated period of embodiment and comparative example, the strain preventive effect investigating each process for 1,3,5,7,14 day after the treatment respectively, its result of the test is in table two.
Table two embodiment and comparative example are to the control efficiency (%) of eleusine indica
Can find out according to data in table, each embodiment of paraquat effervescent is compared with comparative example's Kirchhoff integral, not remarkable to eleusine indica drug effect difference; The each embodiment of paraquat effervescent is compared with the green track of comparative example, and drug effect is significantly better than the green track of comparative example, and significant difference, shows the preventive effect continuation to eleusine indica excellence simultaneously, can reach the effect effectively controlled eleusine indica.
Raw embodiment paraquat effervescent of surveying is tested the herbicidal effect of the rhizome of nutgrass flatsedge.
According to test requirements document, after the rhizome of nutgrass flatsedge with the chemicals treatment growth animated period of embodiment and comparative example, the strain preventive effect investigating each process for 1,3,5,7,14 day after the treatment respectively, its result of the test is in table three.
Table three embodiment and comparative example are to the control efficiency (%) of the rhizome of nutgrass flatsedge
Can find out according to data in table, each embodiment of paraquat effervescent is compared with comparative example's Kirchhoff integral, and to the overall preventive effect of the rhizome of nutgrass flatsedge all at 80%-90%, drug effect difference is not remarkable; The each embodiment of paraquat effervescent is compared with the green track of comparative example, and drug effect is significantly better than the green track of comparative example.
Raw herbicidal effect test of surveying embodiment 4 pairs of green foxtail.
According to test requirements document, after the green foxtail with the chemicals treatment growth animated period of embodiment and comparative example, the strain preventive effect investigating each process for 1,3,5,7,14 day after the treatment respectively, its result of the test is in table four.
Table four embodiment and comparative example are to the control efficiency (%) of green foxtail
Can find out according to data in table, each embodiment of paraquat effervescent is compared with comparative example's Kirchhoff integral, and to the overall preventive effect of green foxtail all about 85%, drug effect difference is lower slightly; The each embodiment of paraquat effervescent is compared with the green track of comparative example, and after medicine, 1 day, 3 days, 5 days drug effects are significantly better than the green track of comparative example, drug effect significant difference; Drug effect no significant difference between respectively processing afterwards for after medicine 7 days, 14 days.
Raw embodiment of surveying is tested the herbicidal effect of Horseweed Herb.
According to test requirements document, after the Horseweed Herb with the chemicals treatment growth animated period of paraquat effervescent embodiment and comparative example, the strain preventive effect investigating each process for 1,3,5,7,14 day after the treatment respectively, its result of the test is in table five.
Table five embodiment and comparative example are to the control efficiency (%) of Horseweed Herb
Can find out according to data in table, each embodiment of paraquat effervescent is compared with comparative example's Kirchhoff integral, and to the overall preventive effect of Horseweed Herb at about 85%-90%, drug effect difference is not remarkable; The each embodiment of paraquat effervescent is compared with the green track of comparative example, and in quick-acting and in whole Weed control effect, drug effect is all significantly better than the green track of comparative example; After medicine 7 days, 14 days drug effects and comparative example's difference not remarkable.
Raw survey embodiment
According to the requirement of Ministry of Agriculture's agricultural chemicals field efficacy criterion, 14 days visually technique of estimation after dispenser, investigate the general control effect of each process to more than field all weeds, investigation result is in table six.
14 days each embodiment process community Weed-control effect hierarchical table after table six medicine
| Process numbering | Embodiment 1 | Embodiment 2 | Embodiment 3 | Kirchhoff integral | Green track | Blank |
| Preventive effect rank | 2 | 2 | 2 | 2 | 3 | 9 |
By recording and can find out in table, paraquat effervescent embodiment is little, basically identical with Kirchhoff integral effect difference on overall herbicidal effect; Preventive effect on the lasting period with to individual plants weeds is better than green track product.
The above; it is only preferred embodiment of the present invention; it is not restriction the present invention being made to other form; the Equivalent embodiments that any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as equivalent variations is applied to other field; but everyly do not depart from technical solution of the present invention content; according to any simple modification, equivalent variations and remodeling that technical spirit of the present invention is done above embodiment, still belong to the protection domain of technical solution of the present invention.
Claims (10)
1. a paraquat effervescent, is characterized in that, this paraquat effervescent comprises following composition by weight:
2. paraquat effervescent according to claim 1, is characterized in that: described dispersant is at least one material in polycarboxylate, di-2-ethylhexylphosphine oxide methyl naphthalene sulfonic acid salt, acrylate copolymer, di-2-ethylhexylphosphine oxide naphthalene sulfonate, lignosulfonates, naphthalenesulfonate formaldehyde condensation compound, Pluronic PE 6800.
3. paraquat effervescent according to claim 1, is characterized in that: described wetting agent is at least one material in Nekal BX, ethoxylated dodecyl alcohol sodium sulphate, polyoxyethylene nonylphenol ether, lauryl sodium sulfate, neopelex, nekal, succinic acid dibutyl ester sodium sulfonate, fatty alcohol-polyoxyethylene ether.
4. paraquat effervescent according to claim 1, is characterized in that: described disintegrant is at least two kinds of materials in urea, potash, calcium carbonate, sodium carbonate, sodium bicarbonate, citric acid, malonic acid, succinic acid, adipic acid, tartaric acid, maleic acid, fumaric acid, benzoic acid, amino acid, potassium dihydrogen phosphate, sorbic acid.
5. paraquat effervescent according to claim 1, is characterized in that: described adhesive is at least one material in starch and derivative thereof, dextrin, polyvinyl alcohol, sodium carboxymethylcellulose, hydroxypropyl cellulose, polyethylene glycol, pyrrolidones, gum Arabic.
6. paraquat effervescent according to claim 1, is characterized in that: described filler is at least one material in stearate, precipitated calcium carbonate, talcum powder, bentonite, atlapulgite, White Carbon black, glucose, lactose, sucrose, starch, diatomite, attapulgite, potter's clay, kaolin.
7. prepare a preparation method for the paraquat effervescent described in any one of the claims 1 ~ 6, it is characterized in that, comprise the following steps:
A, mixing: paraquat, dispersant, wetting agent, disintegrant, filler etc. are mixed and obtains mixture;
B, pulverizing: by mixture through air-flow/ultramicro grinding, obtain female powder;
C, granulation: adhesive and female powder are fully mixed by mixer, by Granulation Equipments granulating and forming;
D, oven dry: the particle obtained is dried.
E, screening: the particle of oven dry is screened.
F, soda acid grain mix: the sour grain obtained after a ~ step e and alkali grain mix by a certain percentage.
8. the preparation method of paraquat effervescent according to claim 7, is characterized in that, described sour grain is the granule made using acid material as disintegrant; Described alkali grain is the granule made using basic materials as disintegrant.
9. the preparation method of paraquat effervescent according to claim 7, is characterized in that, in described step f, sour grain, alkali grain mixed proportion are: 1:25 ~ 25:1.
10. the preparation method of paraquat effervescent according to claim 7, is characterized in that, mixture is crushed to particle diameter≤10 μm by described step b.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510190807.0A CN104886045A (en) | 2015-04-21 | 2015-04-21 | Paraquat effervescent granule and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510190807.0A CN104886045A (en) | 2015-04-21 | 2015-04-21 | Paraquat effervescent granule and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104886045A true CN104886045A (en) | 2015-09-09 |
Family
ID=54019366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510190807.0A Pending CN104886045A (en) | 2015-04-21 | 2015-04-21 | Paraquat effervescent granule and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104886045A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102365955A (en) * | 2011-09-21 | 2012-03-07 | 南京红太阳股份有限公司 | Tablet containing paraquat dichloride and its preparation method |
-
2015
- 2015-04-21 CN CN201510190807.0A patent/CN104886045A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102365955A (en) * | 2011-09-21 | 2012-03-07 | 南京红太阳股份有限公司 | Tablet containing paraquat dichloride and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 张兆旺主编: "《中药药剂学》", 31 March 2007 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104872133A (en) | Paraquat-fluoroglycofen ethyl water-soluble granule and preparation method thereof | |
| CN104672029A (en) | Pesticide fertilizer containing lythidathion | |
| CN103518729B (en) | Insecticidal acaricidal composition and application thereof | |
| CN102369922B (en) | Pyrazosulfuron water dispersible granule and preparation method thereof | |
| CN102239843B (en) | Composition of fluroxypyr or ester of fluroxypyr and fluoroglycofen-ethyl and preparation method thereof | |
| CN105410015B (en) | A kind of chlopyrifos water dispersible granules and preparation method thereof | |
| CN103858866A (en) | Effervescent composition and preparation method thereof | |
| CN106538580A (en) | A kind of Herbicidal combinations containing flupyrsulfuron-methyl-sodium and its application | |
| CN102550560A (en) | Gibberellin effervescent granules or tablets and preparation method thereof | |
| CN106070335A (en) | A kind of composition pesticide and the medicament-fertilizer mixture containing this composition pesticide thereof | |
| CN104886060A (en) | Paraquat - B fluoroglycofen effervescent granules and preparation method | |
| CN101642105B (en) | Uniconazole water dispersible granules and preparation method thereof | |
| CN106259402A (en) | A kind of Herbicidal composition for rice field | |
| CN104996450A (en) | Sterilization composite contained with pyribencarb | |
| CN104886045A (en) | Paraquat effervescent granule and preparation method thereof | |
| CN104982451A (en) | Bactericidal composition containing pyribencarb | |
| CN102450258A (en) | Naphthylacetic acid and naphthylacetic acid saline dispersible granules/or tablets and preparation method thereof | |
| CN101658165A (en) | Mepiquat chloride effervescent tablet and preparation method thereof | |
| CN102450263A (en) | Brassinolide effervescent granules/or effervescent tablets and preparation method thereof | |
| CN108207947A (en) | A kind of diquat dibromide soluble effervescent tablet and preparation method thereof | |
| CN103636639A (en) | Composite herbicide and applications thereof | |
| CN102450261A (en) | Gibberellin water dispersible granule/tablet and preparation method thereof | |
| CN102450262A (en) | Brassinolide water dispersible granule/tablet and preparation method thereof | |
| CN102440244A (en) | Diethylaminoethyl hexanoate organic acid salt water dispersible granules/ tablets and preparation method thereof | |
| CN109497059A (en) | A kind of Herbicidal combinations and preparation method thereof containing triflusulfuronmethyl |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150909 |