CN104878477A - Method for preparing antibacterial alginate fibers through natural antibacterial agent - Google Patents
Method for preparing antibacterial alginate fibers through natural antibacterial agent Download PDFInfo
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- CN104878477A CN104878477A CN201510247113.6A CN201510247113A CN104878477A CN 104878477 A CN104878477 A CN 104878477A CN 201510247113 A CN201510247113 A CN 201510247113A CN 104878477 A CN104878477 A CN 104878477A
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Abstract
The invention discloses a method for preparing antibacterial alginate fibers with different functions through a natural antibacterial agent, and belongs to the technical field of functional transformation of alginate fibers. The method comprises the following steps: dissolving a certain amount of natural antibacterial agent in ethyl alcohol to prepare a natural antibacterial agent solution with certain concentration; soaking alginate fibers in the natural antibacterial agent solution to prepare antibacterial alginate fibers which are free of doubling and disperse naturally; adding distilled water into the natural antibacterial solution while controlling the ratio of the distilled water to ethyl alcohol in the natural antibacterial agent solution, adding a certain amount of sodium alginate powder, heating, stirring to dissolve, and standing for defoaming to prepare a spinning solution containing the natural antibacterial agent; and finally, carrying out coagulating bath, drafting and the like on the spinning solution by adopting a wet spinning method to prepare the antibacterial alginate fibers with continuous antibacterial effect. The natural antibacterial agent is multifunctional and has the effects of solving the doubling problem of the alginate fibers and enhancing the antibacterial effect of the alginate fibers.
Description
Technical field
The invention belongs to the functional renovation technique field of alginate fibre, be specifically related to a kind of method that natural antibacterial agent prepares different antibacterial alginate fibre.
Background technology
Medical dressing plays a part hemostasis, analgesia, anti-inflammatory, promotion wound healing.The medical dressing that calcium alginate fibre is made can carry out ion-exchange with wound diffusate and blood, accelerates the formation of clot, promotes hemostasis.Alginate fibre dressing can form gel thin-layer at wound surface, thus prevent dressing and wound adhesion, alleviate the misery of patient, the humidity and temperature that simultaneously surface of a wound can be made to keep certain, a good microcirculation environment is created in healing for the surface of a wound, promotes wound healing early.
Because alginate fibre is easy to occur doubling phenomena in process of production, so just have a strong impact on subsequent production and the processing of alginate fibre, add cost and the difficulty of medical dressing.The antibacterial effect of alginate fibre itself is limited simultaneously, and as the raw material of medical dressing, antibacterial effect is a very important index.
Summary of the invention
The object of the invention is to solve the doubling of above-mentioned alginate fibre existence and the problem of antibacterial effect difference, the present invention is by the alginate fibre that natural antibacterial agent joined finished product or join in the preparation section of alginate fibre, the antibacterial alginate fibre prepared both had solved doubling problem, in turn enhanced antibacterial effect.
One of task of the present invention is to provide a kind of preparation method of antibacterial alginate fibre, comprises the following steps successively:
A, a certain amount of plants essential oil is dissolved in ethanol, obtained certain density plants essential oil solution;
B, in described plants essential oil solution, add distilled water, and control the ratio of ethanol in described distilled water and plants essential oil solution, then add a certain amount of sodium alginate powder wherein, heating is stirring and dissolving also, standing and defoaming, the obtained spinning solution containing plants essential oil;
C, step b gained spinning solution is adopted wet spinning process, obtained antibacterial alginate fibre after coagulating bath, drawing-off, sizing, dehydration, drying.
As a preferred version of the present invention, in step a, the mass volume ratio of plants essential oil and ethanol is 0.01-0.1:1, and plants essential oil solution adopts the mode of ultrasonic disperse to obtain.
As another preferred version of the present invention, in step b, in distilled water and plants essential oil solution, the volume ratio of ethanol is 1:1.
In step b, in gained spinning solution, the mass percent of sodium alginate is 1-10%.
In step c, in wet spinning process, spinning temperature is 10-50 DEG C, and coagulating bath selects mass percent concentration to be the calcium chloride solution of 1%-15%, and coagulation bath temperature is 30-60 DEG C, and draw ratio is 120-300%.
Two of task of the present invention is to provide the preparation method of another antibacterial alginate fibre, and it comprises the following steps:
1) be dissolved in ethanol by a certain amount of plants essential oil, obtained certain density plants essential oil solution, the mass volume ratio of described plants essential oil and ethanol is 0.01-0.1:1;
2) be impregnated into by finished product alginate fibre tow in steps d gained plants essential oil solution, complete submergence keeps taking out after 10-30 minute, and namely drying obtains antibacterial alginate fibre.
In above-mentioned steps e, finished product alginate fibre tow be impregnated in plants essential oil solution there is no doubling and in nature dispersion antibacterial alginate fibre be good.
Above-mentioned antibacterial alginate fibre is to golden yellow glucose coccus, colibacillary bacteriostasis rate >=90%.
The Advantageous Effects that the present invention brings:
Natural antibacterial agent selected by the present invention and plants essential oil solution have multifunctionality, both can solve the doubling problem of alginate fibre, can strengthen again the antibacterial effect of alginate fibre
Natural antibacterial agent can be applicable to prepare antibacterial alginate fibre in different preparation methods, meanwhile, can also be doped in spinning solution the alginate fibre carrying out wet spinning and prepare sustained anti-microbial.By medical alginate fibre prepared by natural antibacterial agent, reduce the cost of medical dressing making and the difficulty of following process, also enhance antibacterial effect simultaneously, extend the medical scope of alginate fibre.
The inventive method can solve the doubling problem in production, also can strengthen the antibacterial effect of alginate fibre, and also compensate for traditional method while making full use of natural antibacterial agent can not the shortcoming of sustained anti-microbial.
Its sustainable antibacterial 5-10 days of antibacterial alginate fibre that the present invention is prepared by natural antibacterial agent.
Detailed description of the invention
The invention discloses a kind of method that natural antibacterial agent prepares antibacterial alginate fibre, in order to make advantage of the present invention, technical scheme clearly, clearly, below in conjunction with specific embodiment, the invention will be further described.
Raw material selected by the present invention, natural antibacterial agent is selected from the plants essential oil extracted from plant, be taken from herbal flower, leaf, root, bark, fruit, seed, resin etc. to extract with distillation, squeezing mode, the composition containing Antimicrobial preservative in this plants essential oil.
Embodiment 1:
The present invention, a kind of natural antibacterial agent prepares the method for alginate fibre, and it specifically comprises the following steps:
Step 1,0.1g natural antibacterial agent (as Lavender) joined in 100ml alcohol solvent mix, make natural antibacterial agent solution;
Step 2, take 30ml natural antibacterial agent solution and to join in 100ml distilled water to obtain colloidal solution, 1.3g sodium alginate powder is added again in this colloidal solution, under 30 DEG C of conditions, stir 1h, obtained sodium alginate mass percent is the spinning solution containing natural antibacterial agent of 1%;
Step 3, spinning solution obtained for step 2 left standstill, filter, deaeration, by wet spinning process, spinning temperature is 10 DEG C, coagulating bath to be mass percent be 1% calcium chloride solution, coagulation bath temperature is 30 DEG C, obtained antibacterial marine alga as-spun fibre in coagulating bath;
Step 4, antibacterial marine alga as-spun fibre is obtained nano zine oxide alginate fibre through drawing-off, sizing, dehydration, drying, wherein, draw ratio is 120%.
The nano zine oxide alginate fibre prepared by the present embodiment does antibacterial experiment, and its antibacterial lasting effect is 2 days.
Embodiment 2:
The present invention, a kind of natural antibacterial agent prepares the method for alginate fibre, and it specifically comprises the following steps:
Step 1,1.0g natural antibacterial agent (as clove oil) joined in 100ml alcohol solvent mix, make natural antibacterial agent solution;
Step 2, take 20ml natural antibacterial agent solution and to join in 100ml distilled water to obtain colloidal solution, 6.0g sodium alginate powder is added again in this colloidal solution, under 30 DEG C of conditions, stir 2h, obtained sodium alginate mass percent is the spinning solution containing natural antibacterial agent of 5%;
Step 3, spinning solution obtained for step 2 left standstill, filter, deaeration, by wet spinning, spinning temperature is 20 DEG C, coagulating bath to be mass percent be 5% calcium chloride solution, coagulation bath temperature 30 DEG C, obtained antibacterial marine alga as-spun fibre in coagulating bath; Nascent antibacterial alginate fibre is obtained nano zine oxide alginate fibre through drawing-off, sizing, dehydration, drying, and wherein, draw ratio is 150%.
The nano zine oxide alginate fibre prepared by the present embodiment does antibacterial experiment, and its antibacterial lasting effect is 3 days.
Embodiment 3:
The present invention, a kind of natural antibacterial agent prepares the method for alginate fibre, and it specifically comprises the following steps:
Step 1,5.0g natural antibacterial agent (as tea tree ethereal oil) joined in 100ml alcohol solvent mix, make natural antibacterial agent solution;
Step 2, take 10ml natural antibacterial agent solution and to join in 100ml distilled water to obtain colloidal solution, 5.5g sodium alginate powder is added again in colloidal solution, under 40 DEG C of conditions, stir 2h, obtained sodium alginate mass percent is the spinning solution containing natural antibacterial agent of 5%;
Step 3, spinning solution obtained for step 2 left standstill, filter, deaeration, by wet spinning, spinning temperature is 30 DEG C, coagulating bath to be mass percent be 10% calcium chloride solution, coagulation bath temperature 40 DEG C, obtained antibacterial marine alga as-spun fibre in coagulating bath; Antibacterial marine alga as-spun fibre is obtained nano zine oxide alginate fibre through drawing-off, sizing, dehydration, drying, and wherein, draw ratio is 200%.
The nano zine oxide alginate fibre prepared by the present embodiment does antibacterial experiment, and its antibacterial lasting effect is 5 days.
Embodiment 4:
The present invention, a kind of natural antibacterial agent prepares the method for alginate fibre, and it specifically comprises the following steps:
Step 1,8.0g natural antibacterial agent (as Scabrous Mosla Herb essential oil) joined in 100ml alcohol solvent mix, make natural antibacterial agent solution;
Step 2, take 5ml natural antibacterial agent solution and to join in 100ml distilled water to obtain colloidal solution, 8.4g sodium alginate powder is added again in colloidal solution, under 50 DEG C of conditions, stir 3h, obtained sodium alginate mass percent is the spinning solution containing natural antibacterial agent of 8%;
Step 3, spinning solution obtained for step 2 left standstill, filter, deaeration, by wet spinning, spinning temperature is 40 DEG C, coagulating bath to be mass percent be 15% calcium chloride solution, coagulation bath temperature 50 DEG C, obtained antibacterial marine alga as-spun fibre in coagulating bath; Antibacterial marine alga as-spun fibre is obtained nano zine oxide alginate fibre through drawing-off, sizing, dehydration, drying, and wherein, draw ratio is 300%.
The nano zine oxide alginate fibre prepared by the present embodiment does antibacterial experiment, and its antibacterial lasting effect is 7 days.
Embodiment 5:
The present invention, a kind of natural antibacterial agent prepares the method for alginate fibre, and it specifically comprises the following steps:
Step 1,10.0g natural antibacterial agent (as Swamp Mahogany Leaf essential oil) joined in 100ml alcohol solvent mix, make natural antibacterial agent solution;
Step 2, take 1ml natural antibacterial agent solution and to join in 100ml distilled water to obtain colloidal solution, 10.1g sodium alginate powder is added again in colloidal solution, under 50 DEG C of conditions, stir 2h, obtained sodium alginate mass percent is the spinning solution containing natural antibacterial agent of 10%;
Step 3, spinning solution obtained for step 2 left standstill, filter, deaeration, by wet spinning, spinning temperature is 50 DEG C, coagulating bath to be mass percent be 10% calcium chloride solution, coagulation bath temperature 50 DEG C, obtained antibacterial marine alga as-spun fibre in coagulating bath; Antibacterial marine alga as-spun fibre is obtained nano zine oxide alginate fibre through drawing-off, sizing, dehydration, drying, and wherein, draw ratio is 300%.
The nano zine oxide alginate fibre prepared by the present embodiment does antibacterial experiment, and its antibacterial lasting effect is 10 days.
Embodiment 6:
The present invention, a kind of natural antibacterial agent prepares the method for alginate fibre, and it specifically comprises the following steps:
Step 1,12.0g natural antibacterial agent (as Oleum Nigellae) joined in 100ml alcohol solvent mix, make natural antibacterial agent solution;
Step 2, take 1ml natural antibacterial agent solution and to join in 100ml distilled water to obtain colloidal solution, 10.1g sodium alginate powder is added again in colloidal solution, under 30 DEG C of conditions, stir 2h, obtained sodium alginate mass percent is the spinning solution containing natural antibacterial agent of 10%;
Step 3, spinning solution obtained for step 2 left standstill, filter, deaeration, by wet spinning, spinning temperature is 50 DEG C, coagulating bath to be mass percent be 10% calcium chloride solution, coagulation bath temperature 50 DEG C, obtained antibacterial marine alga as-spun fibre in coagulating bath; Antibacterial marine alga as-spun fibre is obtained nano zine oxide alginate fibre through drawing-off, sizing, dehydration, drying, and wherein, draw ratio is 300%.
The nano zine oxide alginate fibre prepared by the present embodiment does antibacterial experiment, and its antibacterial lasting effect is 11 days.
Should be understood that; the above-mentioned description for preferred embodiment is comparatively detailed; therefore the restriction to scope of patent protection of the present invention can not be thought; those of ordinary skill in the art is under enlightenment of the present invention; do not departing under the ambit that the claims in the present invention protect; can also make the various deformation such as replacement, simple combination, request protection domain of the present invention should be as the criterion with claims.
Claims (7)
1. a preparation method for antibacterial alginate fibre, is characterized in that: comprise the following steps successively:
A, a certain amount of plants essential oil is dissolved in ethanol, obtained certain density plants essential oil solution;
B, in described plants essential oil solution, add distilled water, and control the ratio of ethanol in described distilled water and plants essential oil solution, then add a certain amount of sodium alginate powder wherein, heating is stirring and dissolving also, standing and defoaming, the obtained spinning solution containing plants essential oil;
C, step b gained spinning solution is adopted wet spinning process, obtained antibacterial alginate fibre after coagulating bath, drawing-off, sizing, dehydration, drying.
2. the preparation method of antibacterial alginate fibre according to claim 1, is characterized in that: in step a, and the mass volume ratio of described plants essential oil and ethanol is 0.01-0.1:1, and described plants essential oil solution adopts the mode of ultrasonic disperse to obtain.
3. the preparation method of antibacterial alginate fibre according to claim 1, is characterized in that: in step b, and in distilled water and plants essential oil solution, the volume ratio of ethanol is 1:1.
4. the preparation method of antibacterial alginate fibre according to claim 1, is characterized in that: in step b, and in gained spinning solution, the mass percent of sodium alginate is 1-10%.
5. the preparation method of antibacterial alginate fibre according to claim 1, it is characterized in that: in step c, in wet spinning process, spinning temperature is 10-50 DEG C, coagulating bath selects mass percent concentration to be the calcium chloride solution of 1%-15%, coagulation bath temperature is 30-60 DEG C, and draw ratio is 120-300%.
6. a preparation method for antibacterial alginate fibre, is characterized in that, comprises the following steps:
1) be dissolved in ethanol by a certain amount of plants essential oil, obtained certain density plants essential oil solution, the mass volume ratio of described plants essential oil and ethanol is 0.01-0.1:1;
2) be impregnated into by finished product alginate fibre tow in steps d gained plants essential oil solution, complete submergence keeps taking out after 10-30 minute, and namely drying obtains antibacterial alginate fibre.
7. the preparation method of antibacterial alginate fibre according to claim 6, is characterized in that: described antibacterial alginate fibre is to golden yellow glucose coccus, colibacillary bacteriostasis rate >=90%.
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Cited By (8)
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| CN105624833A (en) * | 2016-03-03 | 2016-06-01 | 青岛大学 | Preparation method of magnetic alginate fiber |
| CN106480545A (en) * | 2016-09-21 | 2017-03-08 | 青岛大学 | A kind of preparation method of coloring alginate fiber |
| CN106480544A (en) * | 2016-09-21 | 2017-03-08 | 青岛大学 | A kind of preparation method of Ink sepiellae seu sepiae alginate composite fiber |
| CN106729962A (en) * | 2016-12-21 | 2017-05-31 | 青岛琛蓝海洋生物工程有限公司 | A kind of antibacterial skin protection film liquid and preparation method thereof |
| CN107164825A (en) * | 2017-06-22 | 2017-09-15 | 上海工程技术大学 | A kind of 1,8 eucalyptol health care polysulfonamides fibres and preparation method thereof |
| CN109868525A (en) * | 2019-02-19 | 2019-06-11 | 青岛海赛尔新材料科技有限公司 | A kind of preparation method of high intensity seaweed and polyvinyl alcohol blending fiber |
| CN113041031A (en) * | 2021-03-03 | 2021-06-29 | 山东恒鹏卫生用品有限公司 | Spun-bonded antibacterial non-woven fabric front waist tape for diaper and preparation method thereof |
| CN114059191A (en) * | 2021-12-09 | 2022-02-18 | 上海工程技术大学 | Biodegradable antibacterial fiber and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105624833A (en) * | 2016-03-03 | 2016-06-01 | 青岛大学 | Preparation method of magnetic alginate fiber |
| CN105624833B (en) * | 2016-03-03 | 2017-11-14 | 青岛大学 | The preparation method of magnetic alginate fibre |
| CN106480545A (en) * | 2016-09-21 | 2017-03-08 | 青岛大学 | A kind of preparation method of coloring alginate fiber |
| CN106480544A (en) * | 2016-09-21 | 2017-03-08 | 青岛大学 | A kind of preparation method of Ink sepiellae seu sepiae alginate composite fiber |
| CN106729962A (en) * | 2016-12-21 | 2017-05-31 | 青岛琛蓝海洋生物工程有限公司 | A kind of antibacterial skin protection film liquid and preparation method thereof |
| CN107164825A (en) * | 2017-06-22 | 2017-09-15 | 上海工程技术大学 | A kind of 1,8 eucalyptol health care polysulfonamides fibres and preparation method thereof |
| CN109868525A (en) * | 2019-02-19 | 2019-06-11 | 青岛海赛尔新材料科技有限公司 | A kind of preparation method of high intensity seaweed and polyvinyl alcohol blending fiber |
| CN113041031A (en) * | 2021-03-03 | 2021-06-29 | 山东恒鹏卫生用品有限公司 | Spun-bonded antibacterial non-woven fabric front waist tape for diaper and preparation method thereof |
| CN114059191A (en) * | 2021-12-09 | 2022-02-18 | 上海工程技术大学 | Biodegradable antibacterial fiber and preparation method thereof |
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