CN104873815A - Traditional Chinese medicine for treating common cold and preparing method of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating common cold and preparing method of traditional Chinese medicine Download PDFInfo
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- CN104873815A CN104873815A CN201510280431.2A CN201510280431A CN104873815A CN 104873815 A CN104873815 A CN 104873815A CN 201510280431 A CN201510280431 A CN 201510280431A CN 104873815 A CN104873815 A CN 104873815A
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Abstract
The invention relates to traditional Chinese medicine for treating common cold and a preparing method of the traditional Chinese medicine. The method includes: taking cornu saigae tataricae, fructus arctii, herba schizonepetae, platycodon grandiflorum, liquorice, honeysuckle, lophantherum gracile, semen sojae praeparatum, menthol and forsythia according to certain weight, decocting cornu saigae tataricae to obtain extract, distilling herba schizonepetae and forsythia with steam to obtain distilled liquid, adding honeysuckle, lophantherum gracile, semen sojae praeparatum, cornu saigae tataricae, liquorice, platycodon grandiflorum and water into the residues of herba schizonepetae and forsythia for decocting, standing, filtering and taking supernate, concentrating to obtain clear paste, dissolving menthol with ethanol, combining dissolved menthol with the extract, the distilled liquid and the clear paste, adding single syrup and preservatives, adding water for adjustment, filtering, performing embedment, and sterilizing to obtain the traditional Chinese medicine. The traditional Chinese medicine is capable of clearing heat and toxin, removing phlegm and cough, and moistening lung and depressing qi, evident in curative effect on symptoms such as fever, cough, sore throat caused by common cold, low in cost, free of side effects, and worthy of widely popularizing.
Description
Technical field
The present invention relates to a kind of Chinese medicine and preparation method thereof, particularly relate to a kind of Chinese medicine for the treatment of flu and preparation method thereof.
Background technology
Flu is that the common exogenous diseases emitted caused by ailment said due to cold or exposure is touched in impression.Clinical manifestation is its feature with nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating general malaise etc.General winter of catching a cold is multiple, and its cardinal symptom is obviously afraid of cold, and many clothes are put in timing, are still afraid of cold.Patient's nasal mucus is rarer, and expectorant is thinner, heating, lossless.In general, flu seldom has the situation of the change of disease occurs, the short and being easy to recover of the course of disease, but time sense serious symptom, old man, baby children, weak patients, be again also variable sick it.Because flu has certain infectiousness, very high at infection seasons sickness rate, people ' s health and work, life are brought greater impact, therefore must treatment in time.And at present, the treatment of doctor trained in Western medicine has one-sidedness, and side effect is fairly obvious.Chinese herbal treatment flu is used to be the theme that people study always, the production technology comparatively backwardness of the Chinese herbal medicament oral liquid of existing treatment flu, its oral liquid ubiquity medicinal liquid purity prepared is lower, impurity is more, larger to crude drug waste, and the security performance of product is restricted, and unstable, this just causes curative effect of medication can not be satisfactory.
Summary of the invention
The object of the invention is the defect overcoming prior art existence, a kind of Chinese medicine for the treatment of flu and preparation method thereof is provided, Chinese medicine of the present invention has effect of heat-clearing and toxic substances removing, expelling phlegm for arresting cough, lung moistening sending down the abnormal ascending QI, the symptoms such as the heating caused for catching a cold, cough, throat swell and ache have significant curative effect, with low costly to have no side effect, should be widely promoted.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine for the treatment of flu, and described Chinese medicine comprises following component:
Described Chinese medicine comprises following component:
Described Chinese medicine comprises following component:
Another object of the present invention is the preparation method in order to the Chinese medicine providing above-mentioned treatment to catch a cold, and comprises the steps:
A. each component of Chinese medicine is taken respectively by above-mentioned formula;
B. Cornu Saigae Tataricae decocts to obtain extracting solution, and Herba Schizonepetae, Fructus Forsythiae steam distillation obtain distillate;
C. the residue of Herba Schizonepetae and Fructus Forsythiae decocts 1-3 time after adding Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, Radix Platycodonis and water soaking, and each 1-3 hour, gets decocting liquid at every turn, collecting decoction, leaves standstill, leaching supernatant;
D. the mixed liquor obtained by step c is by intermediate-polarity macroporous adsorption resin or low polar macroporous adsorption resin, rear be first ejected with liquid remaining on cold water flush resin column to resin column after, be the alcoholic solution of 10-20% by concentration be colourless as elution to eluent, be the ethanol elution of 80-95% by concentration again, reclaim eluent, adjust ph is to neutral;
E. concentrated by the eluent that steps d obtains, precipitate with ethanol, gets supernatant, reclaims ethanol to without alcohol taste, obtains clear paste;
F. Mentholum dissolve with ethanol, merge with the extracting solution of above-mentioned steps b-c gained, distillate, clear paste, add simple syrup, antiseptic, add water adjustment, and filter, embedding, sterilizing, to obtain final product.
In described step c, time of repose is 10-14h.
Concentrated in described step e refers under 50-60 DEG C of condition, and being concentrated into relative density is 1.2-1.25.
Precipitate with ethanol process in described step e, for add ethanol in concentrated solution, makes concentration of alcohol reach 60-70%, leaves standstill 20-30h.
Described simple syrup addition is 80-120 weight portion.
Described antiseptic addition is 1-3 weight portion.
Chinese medicine adopting above-mentioned treatment to catch a cold and preparation method thereof, the present invention has the following advantages:
(1) proportioning that the Chinese medicine that the present invention treats flu adopts, can reach the preferably property of medicine, changes that the property of medicine that tablet that traditional medicine makes exists is unstable, dose is large, take the shortcomings such as difficulty;
(2) the present invention treats the preparation method of the Chinese medicine of flu, the part medical materials such as Cornu Saigae Tataricae, Herba Schizonepetae, Fructus Forsythiae are decocted or distillation, there is effect of heat-clearing and toxic substances removing, expelling phlegm for arresting cough, lung moistening sending down the abnormal ascending QI, all the other medical materials first soak with cold water before decoction, avoiding is heated with protein contained by the medical material surface texture that boiling water soaks or decoction brings at the very start easily solidifies, starch gelatinization, hinders moisture to immerse the defects such as crude drug cell inside, improves the fried of medical material effective ingredient;
(3) aperture of macroporous adsorbent resin is all larger with specific surface area, there is in resin inside the three-dimensional pore structure of three dimensions, have that physical and chemical stability is high, specific surface area is large, adsorption capacity is large, selectivity is good, adsorption rate is fast, desorption condition is gentle, Regeneration Treatment is convenient, life cycle is long, be suitable for and form the plurality of advantages such as closed cycle, cost saving, the extraction ratio for effective ingredient is higher;
(4) in sum, the heating that the present invention causes for catching a cold, cough, the throat symptom such as to swell and ache has significant curative effect, with low costly has no side effect, and should be widely promoted.
Detailed description of the invention
A kind of Chinese medicine for the treatment of flu of the present invention, it comprises following component:
Treat a preparation method for the Chinese medicine of flu, comprise the following steps:
A. each component of Chinese medicine is taken respectively by above-mentioned formula;
B. Cornu Saigae Tataricae decocts to obtain extracting solution, and Herba Schizonepetae, Fructus Forsythiae steam distillation obtain distillate;
C. the residue of Herba Schizonepetae and Fructus Forsythiae decocts 1-3 time after adding Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, Radix Platycodonis and water soaking, and each 1-3 hour, gets decocting liquid at every turn, collecting decoction, leaves standstill, leaching supernatant;
D. the mixed liquor obtained by step c is by intermediate-polarity macroporous adsorption resin or low polar macroporous adsorption resin, rear be first ejected with liquid remaining on cold water flush resin column to resin column after, be the alcoholic solution of 10-20% by concentration be colourless as elution to eluent, be the ethanol elution of 80-95% by concentration again, reclaim eluent, adjust ph is to neutral;
E. concentrated by the eluent that steps d obtains, precipitate with ethanol, gets supernatant, reclaims ethanol to without alcohol taste, obtains clear paste;
F. Mentholum dissolve with ethanol, merge with the extracting solution of above-mentioned steps b-c gained, distillate, clear paste, add simple syrup, antiseptic, add water adjustment, and filter, embedding, sterilizing, to obtain final product.
The present invention adopts Cornu Saigae Tataricae, Fructus Arctii, Herba Schizonepetae, Radix Platycodonis, Radix Glycyrrhizae, Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Mentholum, Fructus Forsythiae to configure by certain part by weight, reach the object of optimization, again through decocting, distillation, the step such as concentrated, filtration obtain cold oral liquid, scientific formula, taking convenience, instant effect, within general 2-3 days, cure, cure rate reaches more than 95%.
Example 1
Each raw material of Chinese medicine component is in mass respectively:
Cornu Saigae Tataricae in said components is decocted to obtain extracting solution, Herba Schizonepetae, Fructus Forsythiae steam distillation obtains distillate, the residue of Herba Schizonepetae and Fructus Forsythiae adds Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, decoct 1 time after Radix Platycodonis and water soaking, decoct 1 hour, leave standstill 10 hours, leaching supernatant, supernatant is concentrated into relative density 1.2 under 50 DEG C of conditions, add ethanol, concentration of alcohol is made to reach 60%, leave standstill 20h, get supernatant, reclaim ethanol extremely without alcohol taste, obtain clear paste, Mentholum dissolve with ethanol, with the extracting solution of above-mentioned gained, distillate, clear paste merges, add simple syrup 80 weight portion, antiseptic 1 weight portion, add water adjustment, filter, embedding, sterilizing, obtain, the cold patients of clinical trail 100 all ages and classes levels, within 3 days, cure rate reaches 97%.
Example 2
Each raw material of Chinese medicine component is in mass respectively:
Cornu Saigae Tataricae in said components is decocted to obtain extracting solution, Herba Schizonepetae, Fructus Forsythiae steam distillation obtains distillate, the residue of Herba Schizonepetae and Fructus Forsythiae adds Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, Radix Platycodonis and soak by water 2 times, each 2 hours, get decocting liquid at every turn, collecting decoction, leave standstill 12 hours, leaching supernatant, supernatant is under 55 DEG C of conditions and be concentrated into relative density 1.22, add ethanol, concentration of alcohol is made to reach 65%, leave standstill 25h, get supernatant, reclaim ethanol extremely without alcohol taste, obtain clear paste, Mentholum dissolve with ethanol, with the extracting solution of above-mentioned gained, distillate, clear paste merges, add simple syrup 100 weight portion, antiseptic 2 weight portion, add water adjustment, filter, embedding, sterilizing, obtain, the cold patients of clinical trail 100 all ages and classes levels, within 2 days, cure rate reaches 98%.
Example 3
Each raw material of Chinese medicine component is in mass respectively:
Cornu Saigae Tataricae in said components is decocted to obtain extracting solution, Herba Schizonepetae, Fructus Forsythiae steam distillation obtains distillate, the residue of Herba Schizonepetae and Fructus Forsythiae adds Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, decoct 3 times after Radix Platycodonis and water soaking, each 3 hours, get decocting liquid at every turn, collecting decoction, leave standstill 14 hours, leaching supernatant, supernatant is concentrated into relative density 1.25 under 60 DEG C of conditions, add ethanol, concentration of alcohol is made to reach 70%, leave standstill 30h, get supernatant, reclaim ethanol extremely without alcohol taste, obtain clear paste, Mentholum dissolve with ethanol, with the extracting solution of above-mentioned gained, distillate, clear paste merges, add simple syrup 120 weight portion, antiseptic 3 weight portion, add water adjustment, filter, embedding, sterilizing, obtain, the cold patients of clinical trail 100 all ages and classes levels, within 2 days, cure rate reaches 99%.
Example 4
Each raw material of Chinese medicine component is in mass respectively:
Cornu Saigae Tataricae in said components is decocted to obtain extracting solution, Herba Schizonepetae, Fructus Forsythiae steam distillation obtains distillate, the residue of Herba Schizonepetae and Fructus Forsythiae adds Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, decoct 3 times after Radix Platycodonis and water soaking, each 3 hours, get decocting liquid at every turn, collecting decoction, leave standstill 14 hours, leaching supernatant, supernatant is concentrated into relative density 1.25 under 60 DEG C of conditions, add ethanol, concentration of alcohol is made to reach 70%, leave standstill 30h, get supernatant, reclaim ethanol extremely without alcohol taste, obtain clear paste, Mentholum dissolve with ethanol, with the extracting solution of above-mentioned gained, distillate, clear paste merges, add simple syrup 120 weight portion, antiseptic 3 weight portion, add water adjustment, filter, embedding, sterilizing, obtain, the cold patients of clinical trail 100 all ages and classes levels, within 2 days, cure rate reaches 99%.
Example 5
Each raw material of Chinese medicine component is in mass respectively:
Cornu Saigae Tataricae in said components is decocted to obtain extracting solution, Herba Schizonepetae, Fructus Forsythiae steam distillation obtains distillate, the residue of Herba Schizonepetae and Fructus Forsythiae adds Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, decoct 3 times after Radix Platycodonis and water soaking, each 3 hours, get decocting liquid at every turn, collecting decoction, leave standstill 14 hours, leaching supernatant, supernatant is concentrated into relative density 1.25 under 60 DEG C of conditions, add ethanol, concentration of alcohol is made to reach 70%, leave standstill 30h, get supernatant, reclaim ethanol extremely without alcohol taste, obtain clear paste, Mentholum dissolve with ethanol, with the extracting solution of above-mentioned gained, distillate, clear paste merges, add simple syrup 120 weight portion, antiseptic 3 weight portion, add water adjustment, filter, embedding, sterilizing, obtain, the cold patients of clinical trail 100 all ages and classes levels, within 2 days, cure rate reaches 99%.
Should be appreciated that specific embodiment described above only for explaining the present invention, being not intended to limit the present invention.Still be among protection scope of the present invention by spirit institute's apparent change of extending out of the present invention or change.
Claims (9)
1. treat a Chinese medicine for flu, it comprises following component:
2. a kind of Chinese medicine for the treatment of flu according to claim 1, is characterized in that:
3. a kind of Chinese medicine for the treatment of flu according to claim 1, is characterized in that:
4. prepare a Chinese medicine method for treatment flu as claimed in claim 1, it comprises the steps:
A. each component of Chinese medicine is taken respectively by above-mentioned formula;
B. Cornu Saigae Tataricae decocts to obtain extracting solution, and Herba Schizonepetae, Fructus Forsythiae steam distillation obtain distillate;
C. the residue of Herba Schizonepetae and Fructus Forsythiae decocts 1-3 time after adding Flos Lonicerae, Herba Lophatheri, Semen Sojae Preparatum, Fructus Arctii, Radix Glycyrrhizae, Radix Platycodonis and water soaking, and each 1-3 hour, gets decocting liquid at every turn, collecting decoction, leaves standstill, leaching supernatant;
D. the mixed liquor obtained by step c is by intermediate-polarity macroporous adsorption resin or low polar macroporous adsorption resin, rear be first ejected with liquid remaining on cold water flush resin column to resin column after, be the alcoholic solution of 10-20% by concentration be colourless as elution to eluent, be the ethanol elution of 80-95% by concentration again, reclaim eluent, adjust ph is to neutral;
E. concentrated by the eluent that steps d obtains, precipitate with ethanol, gets supernatant, reclaims ethanol to without alcohol taste, obtains clear paste;
F. Mentholum dissolve with ethanol, merge with the extracting solution of above-mentioned steps b-c gained, distillate, clear paste, add simple syrup, antiseptic, add water adjustment, and filter, embedding, sterilizing, to obtain final product.
5. a kind of preparation method for the treatment of the Chinese medicine of flu according to claim 4, is characterized in that: in described step c, time of repose is 10-14h.
6. a kind of preparation method for the treatment of the Chinese medicine of flu according to claim 4, is characterized in that: concentrated in described step e refers under 50-60 DEG C of condition, and being concentrated into relative density is 1.2-1.25.
7. a kind of preparation method for the treatment of the Chinese medicine of flu according to claim 4, is characterized in that: the precipitate with ethanol process in described step e, for add ethanol in concentrated solution, makes concentration of alcohol reach 60-70%, leaves standstill 20-30h.
8. a kind of preparation method for the treatment of the Chinese medicine of flu according to claim 4, is characterized in that: described simple syrup addition is 80-120 weight portion.
9. a kind of preparation method for the treatment of the Chinese medicine of flu according to claim 4, is characterized in that: described antiseptic addition is 1-3 weight portion.
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Cited By (1)
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| CN116173148A (en) * | 2023-02-18 | 2023-05-30 | 南京同仁堂药业有限责任公司 | Production process and equipment of antelope cold oral liquid |
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