CN104873241B - Leakage stent graft system in the anti-I types of attached spiral shape fluff structures - Google Patents
Leakage stent graft system in the anti-I types of attached spiral shape fluff structures Download PDFInfo
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- CN104873241B CN104873241B CN201410817562.5A CN201410817562A CN104873241B CN 104873241 B CN104873241 B CN 104873241B CN 201410817562 A CN201410817562 A CN 201410817562A CN 104873241 B CN104873241 B CN 104873241B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
- A61B17/12113—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/1215—Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
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Abstract
The present invention relates to stent graft system is leaked in a kind of anti-I types of attached spiral shape fluff structures, leaked for closing in I types, it is characterised in that including：The metal net shaped supporting layer to match with arteries shape；The coating being covered on metal net shaped supporting layer；And it is distributed in the proximal part on the outside of coating or is distributed in the tapetum of proximal part and distal end at the same time, tapetum is filled under the action of natural resiliency in the gap formed between inner wall and coating, wherein, there are more fine hair, the shape of fine hair is spiral shape in tapetum.Leakage stent graft system can close leakage in I types in the anti-I types of the attached spiral shape fluff structures of the present invention.
Description
Technical field
The present invention relates to stent graft system is leaked in a kind of anti-I types of attached spiral shape fluff structures, belong to medical instrument
Field.
Background technology
Aneurysm is that most common initiation one of disables with lethal vascular diseases, it is seen that in any artery of whole body, with
The elderly is common.Aneurysm can have a variety of sizes, shape and distribution, Audit Report special committee of vascular surgery association
(theAd Hoc Committee on Reporting Standards ofthe Society for Vascular
Surgery) defining aneurysm is：The permanent limitation that arteries diameter exceedes natural arterial caliber 50% is expanded, so as to
Classified and standardized in clinical decision.
It is related to attempt earliest to treat aneurysmal record and comes from 3rd century of Christian era, until 1888, Matas et al. is completed
The aneurysm neoplasty of first case truly, i.e., ligature bifurcated artery in the knurl intracavitary of arteria brachialis knurl.Nineteen fifty-one,
Dubost etc. completes first case aneurysm suture and neoplasty, they cut off the abdominal aneurvsm of a patient, and have selected one
The aorta pectoralis of the 20 years old donator of cadaver in position is transplanted in abdominal aortic aneurysms body, the patient is postoperative as alloplast
Survive 8 years.Repair aneurysmal open surgery gradually to improve and optimize in subsequent 40 years, but its peri-operation period is dead
Die rate and be still up to 5%.1991, Parodi et al. is reported first repaired aortic aneurysm using artificial endovascular stent compound
Experience.Food and Drug Admistraton (FDA) approval endovascular graft thing clinical practice after, aneurysm (including peripheral arterial knurl and
Aortic aneurysm) it experienced from open bypass differentiation of the prosthetic to Endovascular repair.
Compared with conventional therapy, the diseases such as endovascular graft treatment aneurysm, artery dissection are carried out using overlay film frame
Disease has the advantages that operation wound is small, post-operative recovery is fast, the hospital stays is short, but its distinctive complication --- interior leakage, to current
It can not still avoid completely.Interior leakage is one of postoperative most important complication of inner cavity insulation, its incidence is up to 45%.Interior leakage presses it
Mechanism can be divided into I-V types, and only just leakage is introduced in I types related to the present invention below.Leakage refers to due to stent in I types
Overlay film and anchorage zone Wall of Artery docile are bad, cause blood flow to leak out to aneurysm cavity through overlay film frame proximal part or distal end
Interior, its incidence about 10%, can often find in Photographg.Because the presence leaked in I types can cause high pressure in aneurysm cavity, dynamic
Arteries and veins knurl continuous enlargement even has the risk ruptured, so needing to immediately treat in art.It is generally believed that proximal landing zone ＜
10mm, and/or 60 ° of knurl neck angulation ＞, the interior leakage incidence of I types will be significantly raised, and wherein anchorage zone refers to that the near of knurl chamber distally has
The normal blood vessels wall of one section of sufficient length is sufficiently sticked with ensureing that intravascular stent and its have, and the vascular wall of such segment length is determined
Justice is anchorage zone (landing zone, LZ), including proximally and distally LZ；Knurl neck angulation refers to knurl neck central axes and sustainer master
Formed angle between dry central axes.At present, it is for leaking general processing mode in the I types that are found in art：Balloon expandable plus use
The stent graft of short section, bare bracket utilize cyanoacrylate, Onyx glue, spring ring, the embolization technique of Fibrin Glue.
These technologies can handle leakage in most of I types；But in some cases will be extremely difficult, such as：Abdominal aneurvsm near-end grappling
Area is too short, and influence arteria renalis blood supply is possible in near-end plus with the stent graft of short section.The summaries such as Maldonado are above-mentioned at present
The effect of leakage in method processing I types：Cyanoacrylate suppository success rate is 92.3%, and near-end short section graft is 80%,
Spring ring is 75%.The problem of no matter taking above-mentioned any processing mode, not only existing success rate, also there is substantial increase
The problem of operating time and medical expense.Also, operating time extends so that patient's art risk, postoperative infection incidence increase
Height, high medical expense bring the financial burden of great number to patient, while take more social resources.
The content of the invention
To solve the above problems, the present invention has redesigned the stent used in endovascular graft, to avoid what is leaked in I types
Occur.
Present invention employs following technical solution：
<Structure one>
Leakage stent graft system, leaks, its feature for closing in I types in a kind of anti-I types of attached spiral shape fluff structures
It is, including：
The metal net shaped supporting layer to match with arteries shape；
The coating being covered on metal net shaped supporting layer；And
The proximal part that is distributed on the outside of coating or the tapetum for being distributed in proximal part and distal end at the same time, tapetum exist
It is filled under the action of natural resiliency in the gap formed between inner wall and coating,
Wherein, there are more fine hair, the shape of fine hair is spiral shape in tapetum.
In addition, leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention, can also have so
Feature：
Wherein, fine hair is directly 25 microns, and the length range of fine hair is 2 millimeters -6 millimeters.
In addition, leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention, can also have so
Feature：
Wherein, the material of fine hair is poly (glycolide-lactide).
In addition, leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention, can also have so
Feature：
Wherein, fine hair is tilted to distal end.
In addition, leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention, can also have so
Feature：
Wherein, tapetum is without departing from metal net shaped supporting layer and the edge of the upper and lower ends of coating.
In addition, leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention, can also have so
Feature：
Wherein, tapetum is made of the material that can adsorb the haemocytes such as clotting factor and blood platelet in blood.
<Structure two>
Leakage stent graft system, leaks, its feature for closing in I types in a kind of anti-I types of attached spiral shape fluff structures
It is, including：
The metal net shaped supporting layer to match with arteries shape；
It is covered in the coating of metal net shaped supporting layer inner surface；And
It is distributed in the proximal part of metal net shaped supporting layer outer surface or is distributed in the fine hair of proximal part and distal end at the same time
Layer, tapetum are filled under the action of natural resiliency in the gap formed between inner wall and coating, wherein, in tapetum
With more fine hair, the shape of fine hair is spiral shape.
Invention effect
Leakage stent graft system in the anti-I types of attached spiral shape fluff structures according to the present invention, due to outside coating layer
Side additionally uses tapetum, and tapetum is filled in the seam formed between inner wall and coating under the action of natural resiliency
In gap so that blood flow cannot can solidify after a period of time has passed directly into knurl chamber in intravillous blood, so that by knurl chamber
It is completely enclosed so that knurl chamber enters stable state.
Brief description of the drawings
Fig. 1 is that stent graft system is leaked in the anti-I types of the attached spiral shape fluff structures of the present invention in embodiment one
Overall structure diagram；
Fig. 2 is the internal structure signal of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention
Figure；
Fig. 3 is the cross-sectional view of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention；
Fig. 4 is showing at leakage stent graft system implantable intravascular in the anti-I types of the attached spiral shape fluff structures of the present invention
It is intended to；
Fig. 5 is the diagrammatic cross-section at BB ' places in Fig. 4；
Fig. 6 is that stent graft system is leaked in the anti-I types of the attached spiral shape fluff structures of the present invention in proximal part and telecentricity
End is respectively provided with schematic diagram villous；And
Fig. 7 is that the tapetum of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention is arranged at
The schematic diagram of rack surface.
Embodiment
Due to causing to be leaked in I types, i.e., since stent overlay film and anchorage zone Wall of Artery docile are bad, cause blood flow through overlay film
The reason for stent proximal part or distal end are leaked out in aneurysm cavity is very much, the anti-I types of attached spiral shape fluff structures of the invention
Interior leakage stent graft system is respectively provided with the effect of prevention for leakage in the I types caused by a variety of causes.In embodiment
Only illustrated so that the stent overlay film caused by arteriosclerosis plaque and anchorage zone Wall of Artery docile are bad as an example.
Illustrate the embodiment of the present invention below in conjunction with attached drawing.
<Embodiment one>
Fig. 1 is the overall structure signal of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention
Figure, Fig. 2 are the internal structure schematic diagrams of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention.Such as
Shown in Fig. 1 and Fig. 2, in the anti-I types of attached spiral shape fluff structures leakage stent graft system 10 include metal net shaped supporting layer 11,
Coating layer 12 and tapetum 13.Metal net shaped supporting layer 11 is located at innermost layer, and coating layer 12 is covered in its outer layer, tapetum 13
Positioned at the outer layer of the proximal part of coating layer 12.
12 common material of coating layer is terylene, also known as ethylene terephthalate.Tapetum 13 is by multiple spiral shapes
Fine hair 131 is covered in overlay film layer surface and is formed, and the material that fine hair 131 uses is poly (glycolide-lactide), chemical name abbreviation PGLA.Suede
One end of hair 131 is connected to 12 surface of coating layer, and other end periphery is stretched out.Poly (glycolide-lactide) material have absorption clotting factor and
The effect of the haemocytes such as blood platelet.Tapetum 13 can be colonized on coating layer.As shown in Figure 1, A directions Digital arteries blood flow side
To one end close to A directions is proximal part, and one end away from A directions is distal end.Side away from heart in distal end Digital arteries
To.Although the incline direction of the single fine hair in tapetum 13 is not consistent, fine hair is generally tilted to telecentricity extreme direction.
And the length of tapetum 13 is without departing from metal net shaped supporting layer and the edge of the proximal part of coating layer.The reason for the two are set
It is the edge stretching that fine hair leaks stent graft system 10 out of anti-I types of the attached spiral shape fluff structures in order to prevent, causes to prop up
The blood flow solidification of frame edge, forms thrombus, the vascular embolization among intravasation under the impact of blood flow.If without fine hair from
Edge stretches out, and blood coagulation is occurred only between stent and vascular wall, do not had in thrombus intravasation.
Fig. 3 is the cross-sectional view of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention, is such as schemed
Shown in 3, flexible fine hair is in the peripheral protruding of coating layer, and direction is different, but generally to the telecentricity of stent
End tilts, and since fine hair is helical form, actual crossing instances can be more finer and close and complicated than what is illustrated in Fig. 3.
Fig. 4 is dynamic on leakage stent graft system implantable intravascular in the anti-I types of the attached spiral shape fluff structures of the present invention
Schematic diagram at arteries and veins knurl, Fig. 5 are the diagrammatic cross-sections at BB ' places in Fig. 4.As shown in Figure 4 and Figure 5, when by attached spiral shape fine hair knot
When leakage stent graft system 10 is implanted into the blood vessel of aneurysm point in the anti-I types of structure, the arteries near knurl chamber 16
It there are arteriosclerosis plaque 15 on 14 vascular wall, arteriosclerosis plaque 15 is prominent into vascular wall, by attached spiral shape fine hair
Fine hair in the anti-I types of structure in the tapetum 13 of leakage stent graft system 10 jacks up, certainly, if arteriosclerosis plaque compared with
Metal net shaped supporting layer 11 can also may be jacked up greatly.Gap is formed between coating layer 12 and blood vessel, this gap is
To be leaked in I types.Since the fine hair 131 in tapetum 13 has elasticity, can be filled among gap, and since fine hair exists
It is subject to direction spiral during the pressure distortion of inner wall that there is randomness, therefore network structure can be formed in gap.Blood is in quilt
Flow velocity in the gap of fine hair filling is greatly reduced, simultaneously because the effect of the clotting factor in blood, through after a while
Remaining blood can solidify in the gap of fine hair filling afterwards, so that by gap closing.
In the presence of gap also have a harmful effect, precisely due to be constantly at gap blood flow impact it
Under, the endothelial cell in blood vessel can not grow into the inside of stent so that the edge of stent cannot be covered by endothelial cell into
And join together with blood vessel endothelium.Stent graft system is leaked in the anti-I types of the attached spiral shape fluff structures of implantation the present embodiment
After system 10, since the blood flow velocity at gap declines so that epithelial cell of the stent gap nearby on vascular wall has sufficiently
Time gradually grows into the inner surface of leakage stent graft system 10 in the anti-I types of attached spiral shape fluff structures, most at last in stent
Surface is completely covered, and joins together with the blood vessel endothelium at both ends.So that stent enters stable state, knurl intracavitary will not be again
Blood is filled with, the blood clotting posterior tuberosity chamber that knurl intracavitary retains can enter stable state, and then endotheli ocytosis, grow into knurl chamber
In so that knurl chamber is not susceptible to rupture.
There are various factors in the PGLA materials biodegradable time, therefore can have the method for a variety of adjustings, here only
A kind of method is provided：Adjusted by the ratio of both monomers of adjusting glycolide and lactide in polymerization, with glycolide
Molar ratio increase in the copolymer, the degradation speed increase of PGLA, works as glycolide：Lactide=50：When 50, degradation time is
50-60 days, work as glycolide：Lactide=85：When 15, degradation time is 150 days.Interior leak blood coagulation is grown into again to fibroblast
Time to the completion of fibrosis can generally complete in two weeks, to ensure that the time for having abundance causes aneurysm cavity and I types
Inside leak into was advisable into stable state, degradation time between 50-150 days, so will not and shadow too short due to PGLA degradation times
Ring the closing of leakage in I types.
The length of poly (glycolide-lactide) microfilament in embodiment one arbitrarily selects between 3.0-4.0mm.
The method for implantation of leakage stent graft system 10 in the anti-I types of attached spiral shape fluff structures：
It is installed on bracket conveyer, passes through by stent graft system 10 is leaked in the anti-I types of attached spiral shape fluff structures
Conveyer is transported at vascular lesion, conveyer is gradually uniformly exited with the stent from swollen characteristic by release device, into
And leakage stent graft system 10 closes the blood flow of knurl intracavitary in the anti-I types of attached spiral shape fluff structures, delivery system is then withdrawn from
System so that stent is permanently disposed on lesion, achievees the purpose that sealing blood vessels knurl knurl chamber.
In surgical procedure, monitor that conveyer enters in human body from parteriole using DSA (Digital subtraction angiograph) and lead
Artery, finally reaches the overall process of knurl chamber.
The effect of embodiment one
Stent graft system is leaked in the anti-I types of attached spiral shape fluff structures in embodiment one, due in overlay film
The proximal part in layer outside employs the tapetum with spiral shape fine hair, and tapetum is filled under the action of natural resiliency
In the gap formed between inner wall and coating layer, when having arteriosclerosis plaque on vascular wall, flexible tapetum
The gap filling formed between the metal net shaped supporting layer and coating layer and blood vessel that will can be propped by arteriosclerosis plaque,
Prevent blood flow from that directly into knurl chamber, can solidify, so that knurl chamber is complete after a period of time has passed in intravillous blood
Closing so that knurl chamber enters stable state.Fine hair interweave the grid to be formed play the role of three aspect, be on the one hand physics resistance
Every so that the flow velocity of blood here slows down significantly, is on the other hand chemical action so as to promote blood coagulation, PGLA can be adsorbed
Clotting factor and blood platelet and haemocyte, further promote blood coagulation；Meanwhile network also acts as the base of fibrosis formation
Matter, contributes to fibroblast to grow into sludged blood, so as to further stablize knurl chamber.
Further, since fine hair 131 is tilted to telecentricity extreme direction and the length of tapetum 13 is without departing from metal net shaped support
The edge of the proximal part of layer and coating layer, therefore can prevent fine hair from leaking stent shifting out of anti-I types of the attached spiral shape fluff structures
The edge of botanical system 10 stretches out, and causes blood flow herein to solidify, forms thrombus, the bolt among intravasation under the impact of blood flow
Fill in blood vessel.
<Embodiment two>
In the present embodiment two, to structure same as the previously described embodiments, this variation, which is given, to be identically numbered, and is saved
Identical explanation.
Fig. 6 is that stent graft system is leaked in the anti-I types of the attached spiral shape fluff structures of the present invention in proximal part and telecentricity
End is respectively provided with schematic diagram villous, as shown in fig. 6, different from embodiment one, the tapetum of the present embodiment is respectively arranged at
The both ends of stent, i.e. proximal part and distal end, certainly, form thrombus, the tapetum at both ends is arranged in the blood vessel in order to prevent
To the intermediate, inclined of stent, and tapetum is arranged to proximal part and the distal end without departing from metal net shaped supporting layer and coating layer
Edge.
It is further prevent distal end from occurring in I types the advantages of proximal part and distal end set tapetum at the same time
The situation of leakage, although the probability that such case occurs is very low, at stent both ends, the setting of equal villous layer can be further
Strengthen the security of stent.
<Embodiment three>
In the present embodiment three, to structure same as the previously described embodiments, this variation, which is given, to be identically numbered, and is saved
Identical explanation.
Fig. 7 is that the tapetum of leakage stent graft system in the anti-I types of the attached spiral shape fluff structures of the present invention is arranged at
The schematic diagram of rack surface, as shown in fig. 7, leakage stent graft system 30 includes gold in the anti-I types of attached spiral shape fluff structures
Belong to mesh-supported layer 31, be covered in the coating layer 32 of metal net shaped 31 inner surface of supporting layer, and be arranged at attached spiral shape fine hair
The tapetum 33 of leakage stent graft system outer face surface, tapetum 33 are made of more fine hair 331 in the anti-I types of structure, suede
Hair 331 is directly connected on metal net shaped supporting layer 31.Coating layer 32 is located in supporting rack, and tapetum is located at the setting outside stent
Manufacturing process it is simpler because the method that fine hair is connected on metallic support is connected to metal net shaped supporting layer compared with by fine hair
On it is more simple and convenient.
In the various embodiments described above, the connection method of fine hair and stent, in addition to fine hair is colonized on coating layer, may be used also
Be colonized fine hair on a conducting wire to first pass through, then on stent as spring spiral winding multi-turn, fine hair is distributed in branch
Frame surface.
The density of fine hair can control every square centimeter in 500-5000 roots in the various embodiments described above.
In addition, the coating layer of the present invention can also be covered in the inner side of metal net shaped supporting layer, so that spongy layer and metal
Mesh-supported layer is directly connected to, and such a lamination order can also reach the technique effect of the present invention.
Claims (4)
1. leakage stent graft system, leaks, its feature exists for closing in I types in a kind of anti-I types of attached spiral shape fluff structures
In, including：
The metal net shaped supporting layer to match with arteries shape；
The coating being covered on the metal net shaped supporting layer；And
The proximal part being distributed on the outside of coating or the proximal part and the tapetum of distal end that are distributed at the same time on the outside of coating,
The tapetum is filled in what is formed between the arterial vascular inner wall and the coating under the action of natural resiliency
In gap,
Wherein, there are more fine hair in the tapetum, the shape of the fine hair is spiral shape,
The material of the fine hair is the poly (glycolide-lactide) that Biodegradation Times are 50 days~150 days,
The fine hair is tilted to distal end, and the tapetum is without departing from the metal net shaped supporting layer and the coating
The edge of proximal part.
2. leakage stent graft system, its feature exist in the anti-I types of attached spiral shape fluff structures according to claim 1
In：
Wherein, the length range of the fine hair is 2 millimeters -6 millimeters.
3. leakage stent graft system, its feature exist in the anti-I types of attached spiral shape fluff structures according to claim 1
In：
Wherein, the poly (glycolide-lactide) polymerize to be formed by glycolide and lactide, and the glycolide rubs with the lactide
You are than being 50:50~85:15.
4. leakage stent graft system, leaks, its feature exists for closing in I types in a kind of anti-I types of attached spiral shape fluff structures
In, including：
The metal net shaped supporting layer to match with arteries shape；
It is covered in the coating of the metal net shaped supporting layer inner surface；And
It is distributed in the proximal part of metal net shaped supporting layer outer surface or is distributed in the near of metal net shaped supporting layer outer surface at the same time
Heart end and the tapetum of distal end, the tapetum are filled in the arterial vascular inner wall and institute under the action of natural resiliency
State in the gap formed between coating, wherein, there are more fine hair, the shape of the fine hair is spiral in the tapetum
Shape,
The material of the fine hair is the poly (glycolide-lactide) that Biodegradation Times are 50 days~150 days,
The fine hair is tilted to distal end, and the tapetum is without departing from the metal net shaped supporting layer and the coating
The edge of proximal part.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410817562.5A CN104873241B (en) | 2014-12-19 | 2014-12-19 | Leakage stent graft system in the anti-I types of attached spiral shape fluff structures |
| PCT/CN2015/097972 WO2016095864A1 (en) | 2014-12-19 | 2015-12-18 | Endoleak-preventing stent graft system |
| US15/537,429 US11007047B2 (en) | 2014-12-19 | 2015-12-18 | Endoleak preventing stent graft system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410817562.5A CN104873241B (en) | 2014-12-19 | 2014-12-19 | Leakage stent graft system in the anti-I types of attached spiral shape fluff structures |
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| Publication Number | Publication Date |
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| CN104873241A CN104873241A (en) | 2015-09-02 |
| CN104873241B true CN104873241B (en) | 2018-05-08 |
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| CN201410817562.5A Expired - Fee Related CN104873241B (en) | 2014-12-19 | 2014-12-19 | Leakage stent graft system in the anti-I types of attached spiral shape fluff structures |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016095864A1 (en) * | 2014-12-19 | 2016-06-23 | 中国人民解放军第二军医大学 | Endoleak-preventing stent graft system |
| CN105496603B (en) | 2015-12-30 | 2018-11-06 | 先健科技(深圳)有限公司 | Intraluminal stent |
| CN108283532A (en) * | 2018-01-15 | 2018-07-17 | 上海长海医院 | Leakage and the art component with spring ring chimney holder in anti- |
| CN115670568B (en) * | 2022-12-28 | 2023-04-07 | 北京华脉泰科医疗器械股份有限公司 | Intracavity occluder and intracavity occluder conveying device |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6015431A (en) * | 1996-12-23 | 2000-01-18 | Prograft Medical, Inc. | Endolumenal stent-graft with leak-resistant seal |
| US7226474B2 (en) * | 2000-05-01 | 2007-06-05 | Endovascular Technologies, Inc. | Modular graft component junctions |
| US20040215322A1 (en) * | 2001-07-06 | 2004-10-28 | Andrew Kerr | Stent/graft assembly |
| CN1217628C (en) * | 2002-09-28 | 2005-09-07 | 维科医疗器械(苏州)有限公司 | Tectorial membrane rack for aorta without inner leakage |
| DE10327231B3 (en) * | 2003-06-13 | 2005-02-17 | Universitätsklinikum Freiburg | Saugstent |
| US8801777B2 (en) * | 2007-04-18 | 2014-08-12 | David Elmaleh | Intravascular device with netting system |
| CN203263585U (en) * | 2013-05-29 | 2013-11-06 | 郭伟 | Support-type blood vessel treating aortic dissection |
| CN204428096U (en) * | 2014-12-19 | 2015-07-01 | 中国人民解放军第二军医大学 | The anti-I type internal hemorrhage due to trauma support of attached spiral type fluff structures |
-
2014
- 2014-12-19 CN CN201410817562.5A patent/CN104873241B/en not_active Expired - Fee Related
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| CN104873241A (en) | 2015-09-02 |
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