CN104857402A - Traditional Chinese medicine composition for treating ankylosing spondylitis - Google Patents
Traditional Chinese medicine composition for treating ankylosing spondylitis Download PDFInfo
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- CN104857402A CN104857402A CN201510286524.6A CN201510286524A CN104857402A CN 104857402 A CN104857402 A CN 104857402A CN 201510286524 A CN201510286524 A CN 201510286524A CN 104857402 A CN104857402 A CN 104857402A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating ankylosing spondylitis. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 20-45 parts of astragalus membranaceus, 10-30 parts of cornu cervi degelatinatum, 10-30 parts of cassia twigs, 5-15 parts of drynaria fortune, 5-15 parts of cinnamomum cassia, 10-30 parts of aster turbinatus, 10-30 parts of Chinese honeylocust, 5-15 parts of ephedra, 5-15 parts of aconitum carmichaeli, 5-15 parts of roots or leaves of dockleaf goldenray, 10-30 parts of pawpaw, 3-10 parts of arisaema calcareum, 5-20 parts of Chinese polyphaga, 10-30 parts of fructus aurantii, 10-30 parts of rhizoma cibotii, 15-30 parts of nancao, 10-30 parts of vernonia cumingiana and 5-15 parts of honey-fried licorice roots. In the traditional Chinese medicine composition, several toxic traditional Chinese medicine raw materials are utilized, that is, the treatment idea of combating poison with poison is adopted, so that the traditional Chinese medicine composition has the advantages of a definite treatment effect on ankylosing spondylitis, a remarkable treatment effect and the like.
Description
Technical field:
The present invention relates to technical field of Chinese medicine, is exactly specifically a kind of Chinese medicine composition for the treatment of ankylosing spondylitis.
Background technology:
The disease that ankylosing spondylitis (AS) is is cardinal symptom with sacroiliac joint and spinal column attachment point inflammation.With HLA-B27 in associating by force.Certain micro-organisms (as klebsiella bacillus) and susceptible person autologous tissue have common antigen, can exception throw immunne response.The large joints of extremity, and annulus fibrosus disci intervertebralis and neighbouring connective fiberization thereof and ossified, and ankylosis is the chronic inflammatory disease of lesion characteristic.Ankylosing spondylitis belongs to rheumatism category, is the one of seronegative spondyloanthropathy.
The traditional Chinese medical science thinks that primary disease is solid by body imbalance of YIN and YANG, healthy energy, the evil impatency meridians of diseases caused by exogenous pathogenic factor wind, cold, wet, heat, QI and blood impatency, pathogen heat-transformation, and causes deficiency of kidney-QI, essence and blood loses, joint muscle arteries and veins cervical carcinoma with cachexia is foster falls ill; Clinically to show as: muscle bones and muscles pain, numbness, joint stuffiness, arthroncus, the symptom such as scorching hot more.
Doctor trained in Western medicine thinks that this cause of disease is still not clear, and is take spinal column as the chronic disease at major lesions position, involves sacroiliac joint, cause rigid spine and fibrosis, cause eye, lung, muscle, skeleton pathological changes in various degree, belong to autoimmune disease.Therefore western medical treatment of the prior art with non-carrier anti-inflammation analgesia medicine, immunosuppressant for first-selection.But there is unsatisfactory curative effect, and the problem such as toxic and side effects is larger.
Summary of the invention:
The present invention is exactly to overcome deficiency of the prior art, provides a kind of Chinese medicine composition for the treatment of ankylosing spondylitis.
The invention provides following technical scheme:
A kind of Chinese medicine composition for the treatment of ankylosing spondylitis, it is characterized in that it comprises the raw material of Chinese medicine of following composition by weight: Radix Astragali 20-45 part, Cornu Cervi Degelatinatum 10-30 part, Ramulus Cinnamomi 10-30 part, monkey Rhizoma Zingiberis Recens 5-15 part, Cortex Cinnamomi 5-15 part, Radix Stemonae 10-30 part, Spina Gleditsiae 10-30 part, Herba Ephedrae 5-15 part, Radix Aconiti Lateralis Preparata 5-15 part, Radix seu Folium Ligulariae Lapathifoliae 5-15 part, Fructus Chaenomelis 10-30 part, Arisaema balansae Engl. 3-10 part, Eupolyphaga Seu Steleophaga 5-20 part, Fructus Aurantii 10-30 part, Rhizoma Cibotii 10-30 part, southern careless 15-30 part, Cortex Ampelopsis Aconitifoliae Radicis 10-30 part, Radix Glycyrrhizae Preparata 5-15 part.
Can also add further in above-mentioned raw materials, the raw material of Chinese medicine of following weight proportion:
Fructus Xanthii 3-10 part, Gryllus Chinensis 5-15 part.
Radix Achyranthis Bidentatae 10-30 part, Radix Paeoniae Alba 10-30 part.
Radix Cyathulae 10-30 part, Radix Paeoniae Alba (parched) 10-30 part.
Form being described in detail as follows of each raw material of Chinese medicine of the present invention:
The Radix Astragali: sweet in the mouth, warm in nature.Return lung, spleen channel.There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effects such as expelling pus and promoting granulation.Be usually used in the deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, the diseases such as diabetes.
Cornu Cervi Degelatinatum: salty in the mouth, warm in nature.Return liver, kidney channel.There is warming the kidney to activate YANG, the effects such as astringing to arrest bleeding.Be usually used in spleen kidney yang flaccidity, lack of appetite and vomiting, leucorrhea, enuresis frequent micturition, metrostaxis, the diseases such as carbuncle sucutaneous nodule.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.GUIXIN, lung, urinary bladder channel.There is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, flat effects such as gas of spining.Be usually used in anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, the diseases such as renal mass.
Monkey Rhizoma Zingiberis Recens: i.e. Rhizoma Drynariae.Bitter in the mouth, warm in nature.Return kidney, Liver Channel.There is the kidney invigorating bone strengthening, continue and hinder the effects such as pain relieving.Be usually used in lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, the diseases such as vitiligo.
Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature.Return kidney, spleen, the heart, Liver Channel.There is benefit fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, the effects such as promoting blood circulation to restore menstrual flow.Be usually used in sexual impotence, cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, the diseases such as dysmenorrhea.
Radix Stemonae: the i.e. Radix Stemonae.Sweet in the mouth, hardship, slightly warm in nature.Return lung meridian.Slightly poisonous.There is nourishing the lung to keep the adverse QI downward cough-relieving, the effects such as parasite killing.Be usually used in new chronic cough to cough, pulmonary tuberculosis cough, pertussis; Outer for head louse, body louse, enterobiasis, the diseases such as pudendal pruritus.
Spina Gleditsiae: i.e. Spina Gleditsiae.Acrid in the mouth, warm in nature.Return liver, stomach warp.There is detumescence poison holding, evacuation of pus, the effects such as parasite killing.Be usually used in carbuncle from the beginning of or difficulty in discharging of pus; The diseases such as external treatment scabies leprosy.
Herba Ephedrae: acrid in the mouth; Micro-hardship; Warm in nature.Return lung; Urinary bladder channel.There is relieving the exterior syndrome by diaphoresis; Depressed lung-energy dispersing; The effects such as inducing diuresis to remove edema.Be usually used in chill exterior syndrome; Fever with aversion to cold; Lossless; Headache body pain; Heresy is stopped up in lung; Inhibited pulmonary QI; Cough and asthma; Edema caused by wind; Dysuria; Rheumatic arthralgia; Numbness of the skin and rubella pruritus; The diseases such as carbuncle of yin nature sucutaneous nodule.
Radix Aconiti Lateralis Preparata: acrid in the mouth, sweet, extremely hot in nature; Poisonous.GUIXIN, kidney, spleen channel.There is recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, by effects such as wind-cold damp pathogens.Be usually used in YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, the diseases such as arthralgia due to cold-dampnes.Radix Aconiti Lateralis Preparata is the Radix Aconiti Lateralis Preparata after concocting, and reduces the toxicity of Radix Aconiti Lateralis Preparata.
Radix seu Folium Ligulariae Lapathifoliae: acrid in the mouth; Micro-hardship; Hot in nature; Mild toxicity.GUIXIN, spleen two warp.There is dissipating blood stasis, invigorate blood circulation, the effects such as pain relieving.Be usually used in traumatic injury, pain caused by ecchymoma, the diseases such as rheumatic arthralgia.
Fructus Chaenomelis: sour in the mouth, temperature.Return liver, spleen channel.There is suppressing the hyperactive liver relaxing muscles and tendons, the effects such as stomach function regulating removing dampness.For arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, convulsion of vomiting and diarrhoea, the diseases such as beriberi edema.
Arisaema balansae Engl.: this product is generally medicine for external use.Acrid in the mouth, cold in nature.Return Liver Channel.Very toxic.There is removing toxic substances, the effects such as reducing swelling and alleviating pain.Carbuncle pyogenic infections from tumour or sore is controlled in external, mastitis, parotitis, the diseases such as venom.
Eupolyphaga Seu Steleophaga: salty in the mouth, cold in nature; Slightly poisonous.Return Liver Channel.There is removing blood stasis with potent drugs blood, the effects such as reuniting the fractured tendons and bones.Be usually used in injured bone, blood stasis amenorrhea, the diseases such as lump in the abdomen mass in the abdomen.
This product also has anticoagulation and to Fibrinolytic effect; To the effect of histanoxia; And the effect of adjusting blood lipid.
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, the effects such as the stagnant relieving distension of row.Be usually used in the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official such as to prolapse the disease.
Rhizoma Cibotii: bitter in the mouth, sweet, warm in nature.Return liver, kidney channel.There is invigorating the liver and kidney, strong spinal column, the effects such as wind-damp dispelling.Be usually used in soreness of the waist and knees, weakness of the lower extremities, the diseases such as rheumatic arthralgia.
South grass: the another name being Radix Dipsaci.Bitter in the mouth, pungent, slightly warm in nature.Return liver, kidney channel.Have invigorating the liver and kidney, bone and muscle strengthening, continuous injured, stops the effects such as metrorrhagia.Be usually used in soreness of the waist and knees, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, the diseases such as injury from falling down.
Cortex Ampelopsis Aconitifoliae Radicis: acrid in the mouth; Hot in nature.GUIXIN; Kidney channel.There is expelling wind and removing dampness; The effects such as dissipating blood stasis for subsidence of swelling.Be usually used in anemofrigid-damp arthralgia; Traumatic injury congestive edema; The diseases such as ulcer sore pain.
Radix Glycyrrhizae Preparata: this product is the Preparation process product of Radix Glycyrrhizae.Sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.There is spleen reinforcing stomach function regulating, the effects such as Yiqi and vein recovery.Be usually used in weakness of the spleen and stomach, fatigue and weakness, severe palpitation, the diseases such as irregularly intermittent and regularly intermittent pulse.
Fructus Xanthii: acrid in the mouth, hardship, warm in nature; Poisonous.Return lung meridian.There is the dehumidifying of loose wind, the effects such as clearing the nasal passage.Be usually used in headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, the diseases such as arthralgia chiefly caused by damp pathogen contracture.
Gryllus Chinensis: acrid in the mouth, salty, warm in nature.Poisonous.Return bladder; Small intestine meridian.There is diuresis, the effects such as removing blood stasis.Be usually used in edema, urinary obstruction, lithangiuria, the diseases such as cirrhotic ascites.
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down.GUIXIN, liver, large intestine three warp.There is promoting blood circulation to remove blood stasis, damp eliminating diuresis, the effects such as heat-clearing and toxic substances removing.Control gonorrhea, hematuria, women's amenorrhea, lump in the abdomen, rheumatic arthritis, beriberi, edema, dysentery, malaria, diphtheria, carbuncle, the diseases such as traumatic injury.This product is partial to tonifying liver and kidney and strengthening bones and muscles compared with Radix Cyathulae.
Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Return liver, spleen channel.There is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, the effects such as astringing YIN to stop sweating.Be usually used in headache dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, the diseases such as night sweat.
Radix Paeoniae Alba can significantly increase myocardial blood flow amount, has raising blood pressure and strengthens hear sounds effect.Radix Paeoniae Alba can the formation of anticoagulant and thrombosis.
Radix Cyathulae: sweet in the mouth, micro-hardship, property is put down.Return liver, kidney channel.There is eliminating blood stasis and inducing menstruation, easing joint movement, the effects such as inducing diuresis for treating stranguria syndrome.Be usually used in amenorrhea lump in the abdomen, retention of placenta, injury from falling down, rheumatic arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, the cards such as hematuria stranguria with blood.This product is partial to blood circulation promoting and blood stasis dispelling compared with Radix Achyranthis Bidentatae.
Radix Paeoniae Alba (parched): Radix Paeoniae Alba (parched) is also known as Radix Paeoniae Alba (processed).For Radix Paeoniae Alba sheet bran is fried to micro-Huang, slightly focal spot with slow fire, sieve removes Testa Tritici, the cool person of being used as medicine of drying in the air.The Radix Paeoniae Alba (parched) property of medicine is slightly slow, based on the yin fluid astringing that nourishes blood.Be longer than the regulating liver-QI that nourishes blood after stir-fry, be used for the insufficiency of the spleen pain of the liver-yang hyperactivity person of rushing down, the borborygmus as insufficiency of the spleen for liver-yang hyperactivity are suffered from abdominal pain, the tongxieyao formula (Jing-Yue Complete Works) of having loose bowels; Control dysentery with the passing of time, the foster dirty soup (" formulary of peaceful benevolent dispensary ") of abdominal pain alleviated by pressure happiness temperature.
Preparation method:
Remove above-mentioned raw material of Chinese medicine by weight ratio, animal raw materials taking-up hands is torn up rear for subsequent use, first other medicines big fire is boiled, then turn little fire and decoct 45-60 minute, then put by animal raw materials into the liquid, turn big fire and continue decoction 15 minutes, gained is Chinese medicine composition of the present invention.
Instructions of taking:
Every day 1 dose, decocting, early, evening takes at twice.
Clinical data:
My institute is the random selecting patients with ankylosing spondylitis of 15 ~ 56 years old 100 example between in January, 2012 to 2014 year December, is divided into treatment group and matched group two groups at random.
Wherein, treatment group 50 example, male 35 example, women 15 example, 30.5 years old mean age.
Matched group 50 example, male 35 example, women 15 example, the mean age is 28.3 years old.
Treatment group takes the Chinese medicine composition prepared by the formula of embodiment 3, and every day is oral meal at twice.
Matched group takes sulfasalazine and methotrexate, and each 0.5g, every day is oral meal at twice.
Questionnaire statistical analysis body sense by inquiry, and by checking rheumatoid factor and X radiological survey X therapeutic effect:
Invalid: drug administration is without any effective effect.
Slight suppression symptom: slight relief pain and stiff, can improve patients ' life quality.
Effective suppression symptom: effectively alleviating pain and stiff, effectively improves patients ' life quality.
Cure: rheumatoid factor and X radiological survey X therapeutic effect reach and change completely.
Therapeutic outcome:
Treatment group: slight suppression 8 people, effectively suppresses 42 people, suppresses effective percentage 84%.
Contrast groups: invalid 19 people, slight suppression 10 people, effectively suppress 21 people, suppress effective percentage 42%.
The invention has the advantages that:
The present invention has tonifying liver blood, kidney tonifying essence, nourishing YIN and clearing away heat, activating QI clearance, nourishing blood to tranquillize the mind, soothing the liver pathogenic fire reducing, nourishing YIN contain sun, bone and muscle strengthening, nourishing kidney are invigorated blood circulation, strengthened endocrine effect.Present invention uses the poisonous raw material of Chinese medicine of some especially, adopt the treatment concept for the treatment of the poisonous disease with poisonous drugs, make the advantages such as the present invention has determined curative effect for the treatment of ankylosing spondylitis, and therapeutic effect is obvious.
Detailed description of the invention:
Embodiment 1:
Treat a Chinese medicine composition for ankylosing spondylitis, it is characterized in that it comprises the raw material of Chinese medicine of following composition by weight: the Radix Astragali 40 parts, Cornu Cervi Degelatinatum 25 parts, Ramulus Cinnamomi 25 parts, monkey Rhizoma Zingiberis Recens 13 parts, Cortex Cinnamomi 13 parts, Radix Stemonae 22 parts, Spina Gleditsiae 21 parts, 12 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 10 parts, Radix seu Folium Ligulariae Lapathifoliae 13 parts, Fructus Chaenomelis 22 parts, Arisaema balansae Engl. 8 parts, Eupolyphaga Seu Steleophaga 13 parts, Fructus Aurantii 22 parts, Rhizoma Cibotii 25 parts, south grass 24 parts, Cortex Ampelopsis Aconitifoliae Radicis 15 parts, Radix Glycyrrhizae Preparata 10 parts.
Embodiment 2:
Treat a Chinese medicine composition for ankylosing spondylitis, it is characterized in that it comprises the raw material of Chinese medicine of following composition by weight: the Radix Astragali 45 parts, Cornu Cervi Degelatinatum 25 parts, Ramulus Cinnamomi 28 parts, monkey Rhizoma Zingiberis Recens 10 parts, Cortex Cinnamomi 10 parts, Radix Stemonae 25 parts, Spina Gleditsiae 15 parts, 8 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 8 parts, Radix seu Folium Ligulariae Lapathifoliae 8 parts, Fructus Chaenomelis 20 parts, Arisaema balansae Engl. 5 parts, Eupolyphaga Seu Steleophaga 15 parts, Fructus Aurantii 26 parts, Rhizoma Cibotii 25 parts, south grass 24 parts, Cortex Ampelopsis Aconitifoliae Radicis 24 parts, Radix Glycyrrhizae Preparata 10 parts, Fructus Xanthii 6 parts, Gryllus Chinensis 11 parts.
Embodiment 3:
Treat a Chinese medicine composition for ankylosing spondylitis, it is characterized in that it comprises the raw material of Chinese medicine of following composition by weight: the Radix Astragali 30 parts, Cornu Cervi Degelatinatum 28 parts, Ramulus Cinnamomi 26 parts, monkey Rhizoma Zingiberis Recens 10 parts, Cortex Cinnamomi 10 parts, Radix Stemonae 22 parts, Spina Gleditsiae 25 parts, 15 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 10 parts, Radix seu Folium Ligulariae Lapathifoliae 8 parts, Fructus Chaenomelis 26 parts, Arisaema balansae Engl. 5 parts, Eupolyphaga Seu Steleophaga 15 parts, Fructus Aurantii 22 parts, Rhizoma Cibotii 26 parts, south grass 27 parts, Cortex Ampelopsis Aconitifoliae Radicis 15 parts, Radix Glycyrrhizae Preparata 13 parts, Fructus Xanthii 5 parts, Gryllus Chinensis 10 parts, Radix Achyranthis Bidentatae 25 parts, Radix Paeoniae Alba 25 parts.
Embodiment 4:
Treat a Chinese medicine composition for ankylosing spondylitis, it is characterized in that it comprises the raw material of Chinese medicine of following composition by weight: the Radix Astragali 43 parts, Cornu Cervi Degelatinatum 26 parts, Ramulus Cinnamomi 28 parts, monkey Rhizoma Zingiberis Recens 14 parts, Cortex Cinnamomi 15 parts, Radix Stemonae 22 parts, Spina Gleditsiae 25 parts, 13 parts, Herba Ephedrae, Radix Aconiti Lateralis Preparata 15 parts, Radix seu Folium Ligulariae Lapathifoliae 15 parts, Fructus Chaenomelis 25 parts, Arisaema balansae Engl. 8 parts, Eupolyphaga Seu Steleophaga 20 parts, Fructus Aurantii 30 parts, Rhizoma Cibotii 30 parts, south grass 30 parts, Cortex Ampelopsis Aconitifoliae Radicis 30 parts, Radix Glycyrrhizae Preparata 15 parts, Fructus Xanthii 8 parts, Gryllus Chinensis 15 parts, Radix Cyathulae 30 parts, Radix Paeoniae Alba (parched) 30 parts.
Claims (4)
1. treat the Chinese medicine composition of ankylosing spondylitis for one kind, it is characterized in that it comprises the raw material of Chinese medicine of following composition by weight: Radix Astragali 20-45 part, Cornu Cervi Degelatinatum 10-30 part, Ramulus Cinnamomi 10-30 part, monkey Rhizoma Zingiberis Recens 5-15 part, Cortex Cinnamomi 5-15 part, Radix Stemonae 10-30 part, Spina Gleditsiae 10-30 part, Herba Ephedrae 5-15 part, Radix Aconiti Lateralis Preparata 5-15 part, Radix seu Folium Ligulariae Lapathifoliae 5-15 part, Fructus Chaenomelis 10-30 part, Arisaema balansae Engl. 3-10 part, Eupolyphaga Seu Steleophaga 5-20 part, Fructus Aurantii 10-30 part, Rhizoma Cibotii 10-30 part, southern careless 15-30 part, Cortex Ampelopsis Aconitifoliae Radicis 10-30 part, Radix Glycyrrhizae Preparata 5-15 part.
2., according to a kind of Chinese medicine for the treatment of ankylosing spondylitis described in claim 1, it is characterized in that the raw material of Chinese medicine that can also add following composition by weight in above-mentioned raw material of Chinese medicine further: Fructus Xanthii 3-10 part, Gryllus Chinensis 5-15 part.
3., according to a kind of Chinese medicine for the treatment of ankylosing spondylitis described in claim 2, it is characterized in that the raw material of Chinese medicine that can also add following composition by weight in above-mentioned raw material of Chinese medicine further: Radix Achyranthis Bidentatae 10-30 part, Radix Paeoniae Alba 10-30 part.
4., according to a kind of Chinese medicine for the treatment of ankylosing spondylitis described in claim 2, it is characterized in that the raw material of Chinese medicine that can also add following composition by weight in above-mentioned raw material of Chinese medicine further: Radix Cyathulae 10-30 part, Radix Paeoniae Alba (parched) 10-30 part.
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Application publication date: 20150826 |