CN104854069B - 由6,10‑二甲基十一碳‑5‑烯‑2‑酮或6,10‑二甲基十一碳‑5,9‑二烯‑2‑酮制备的(6r,10r)‑6,10,14‑三甲基十五烷‑2‑酮 - Google Patents

由6,10‑二甲基十一碳‑5‑烯‑2‑酮或6,10‑二甲基十一碳‑5,9‑二烯‑2‑酮制备的(6r,10r)‑6,10,14‑三甲基十五烷‑2‑酮 Download PDF

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CN104854069B
CN104854069B CN201380065785.4A CN201380065785A CN104854069B CN 104854069 B CN104854069 B CN 104854069B CN 201380065785 A CN201380065785 A CN 201380065785A CN 104854069 B CN104854069 B CN 104854069B
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carbon
ketone
alkene
formula
dimethyl
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CN104854069A (zh
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沃纳·邦拉蒂
托马斯·内切尔
乔纳森·艾伦·米德洛克
雷奈·托拜厄斯·史德姆勒
约翰内斯·提斯楚米
格拉尔杜斯·卡雷尔·玛丽亚·韦尔兹尔
安德里亚斯·翰德里克斯·玛丽亚·弗里斯·德
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DSM IP Assets BV
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/44—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by addition reactions, i.e. reactions involving at least one carbon-to-carbon double or triple bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/87—Preparation of ketenes or dimeric ketenes
    • C07C45/90—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
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    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0033—Iridium compounds
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    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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CN201380065785.4A 2012-12-18 2013-12-18 由6,10‑二甲基十一碳‑5‑烯‑2‑酮或6,10‑二甲基十一碳‑5,9‑二烯‑2‑酮制备的(6r,10r)‑6,10,14‑三甲基十五烷‑2‑酮 Active CN104854069B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12197835.7 2012-12-18
EP12197835 2012-12-18
PCT/EP2013/077187 WO2014096065A1 (en) 2012-12-18 2013-12-18 (6r,10r)-6,10,14-trimetylpentadecan-2-one prepared from 6,10-dimetylundec-5-en-2-one or 6,10-dimetylundeca-5,9-dien-2-one

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CN104854069A CN104854069A (zh) 2015-08-19
CN104854069B true CN104854069B (zh) 2017-06-20

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CN201380065785.4A Active CN104854069B (zh) 2012-12-18 2013-12-18 由6,10‑二甲基十一碳‑5‑烯‑2‑酮或6,10‑二甲基十一碳‑5,9‑二烯‑2‑酮制备的(6r,10r)‑6,10,14‑三甲基十五烷‑2‑酮

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US (1) US9452961B2 (enExample)
EP (1) EP2935177B1 (enExample)
JP (1) JP6481171B2 (enExample)
CN (1) CN104854069B (enExample)
BR (1) BR112015014335B1 (enExample)
EA (1) EA028852B1 (enExample)
ES (1) ES2746749T3 (enExample)
MY (1) MY195300A (enExample)
WO (1) WO2014096065A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA033302B9 (ru) * 2012-12-18 2020-01-22 ДСМ АйПи АССЕТС Б.В. (6r,10r)-6,10,14-триметилпентадекан-2-он, получаемый из 6,10,14-триметилпентадека-5,9,13-триен-2-она или 6,10,14-триметилпентадека-5,9-диен-2-она
JP6390048B2 (ja) * 2012-12-18 2018-09-19 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 組み合わされた不斉水素化によって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
JP6476496B2 (ja) * 2012-12-18 2019-03-06 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． ケタールおよびアセタールの不斉水素化の方法
JP6406676B2 (ja) * 2012-12-18 2018-10-17 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 不斉水素化および異性化を組み合わせることによって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
WO2018108606A1 (en) * 2016-12-12 2018-06-21 Dsm Ip Assets B.V. Process for the manufacture of 6,10-dimethylundecan-2-one, isophytol, alpha-tocopherol (acetate) and further intermediates thereof
EP3470388A1 (en) * 2017-10-13 2019-04-17 Basf Se Synthesis of aliphatic alcohols as aroma chemicals
EP4034527A1 (en) * 2019-09-25 2022-08-03 Bayer Aktiengesellschaft Improved enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst and an additive
EP4039670A1 (en) * 2021-02-08 2022-08-10 DSM IP Assets B.V. Manufacturing of allene ketones using copper sulfate or a hydrate thereof
CN118619908A (zh) * 2024-05-28 2024-09-10 无锡小荷智化科技有限公司 一种4,6-二甲基-2-氧-2h-吡喃-5-甲酸乙酯的绿色合成工艺

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292459A (en) * 1975-07-16 1981-09-29 Scm Corporation Coupling reaction involving a Grignard and allylic halide
EP0574783B1 (de) * 1992-06-19 1999-10-06 F. Hoffmann-La Roche Ag Asymmetrische Hydrierung
CN101087774A (zh) * 2004-12-22 2007-12-12 帝斯曼知识产权资产管理有限公司 用手性铱络合物对烯烃的非对称氢化

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US4028385A (en) * 1974-09-02 1977-06-07 Kuraray Co., Ltd. Process for preparing stereospecific farnesylacetic acid and ester thereof
DK0565975T3 (da) * 1992-04-16 1996-10-14 Hoffmann La Roche Fremgangsmåde til fremstilling af isoprenderivater
US5955636A (en) * 1996-07-05 1999-09-21 Kuraray Co., Ltd. Process for producing 6-methyl-3-hepten-2-one and 6-methyl-2-heptanone analogues, and process for producing phyton or isophytol
EA033302B9 (ru) * 2012-12-18 2020-01-22 ДСМ АйПи АССЕТС Б.В. (6r,10r)-6,10,14-триметилпентадекан-2-он, получаемый из 6,10,14-триметилпентадека-5,9,13-триен-2-она или 6,10,14-триметилпентадека-5,9-диен-2-она
JP6390048B2 (ja) * 2012-12-18 2018-09-19 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 組み合わされた不斉水素化によって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用
JP6406676B2 (ja) * 2012-12-18 2018-10-17 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 不斉水素化および異性化を組み合わせることによって特定の生成物を定量的に得るためのｅ／ｚ異性体の混合物の使用

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292459A (en) * 1975-07-16 1981-09-29 Scm Corporation Coupling reaction involving a Grignard and allylic halide
EP0574783B1 (de) * 1992-06-19 1999-10-06 F. Hoffmann-La Roche Ag Asymmetrische Hydrierung
CN101087774A (zh) * 2004-12-22 2007-12-12 帝斯曼知识产权资产管理有限公司 用手性铱络合物对烯烃的非对称氢化

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JP6481171B2 (ja) 2019-03-13
US9452961B2 (en) 2016-09-27
EP2935177A1 (en) 2015-10-28
BR112015014335A2 (pt) 2017-07-11
EA201500648A1 (ru) 2015-12-30
JP2015537054A (ja) 2015-12-24
EA028852B1 (ru) 2018-01-31
US20150329457A1 (en) 2015-11-19
MY195300A (en) 2023-01-12
WO2014096065A1 (en) 2014-06-26
CN104854069A (zh) 2015-08-19
ES2746749T3 (es) 2020-03-06
BR112015014335B1 (pt) 2020-12-08
EP2935177B1 (en) 2019-07-24

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