CN104840813B - It is a kind of to treat Chinese medicine of the liver cancer with chronic hepatitis B - Google Patents
It is a kind of to treat Chinese medicine of the liver cancer with chronic hepatitis B Download PDFInfo
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- CN104840813B CN104840813B CN201510247259.0A CN201510247259A CN104840813B CN 104840813 B CN104840813 B CN 104840813B CN 201510247259 A CN201510247259 A CN 201510247259A CN 104840813 B CN104840813 B CN 104840813B
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Abstract
The invention belongs to the field of Chinese medicines, discloses a kind of Chinese medicine for treating liver cancer companion's chronic hepatitis B, including following medicinal material：Radix pseudostellariae, the Radix Astragali, arillus longan, Poria cocos, Chinese yam, Canton love-pea vine, oldenlandia diffusa, Sculellaria barbata, radix bupleuri, oriental wormwood, the fruit of Chinese magnoliavine, coix seed, turtle shell, rhizoma alismatis, corydalis tuber, the fruit of Chinese wolfberry, the membrane of a chicken's gizzard, jujube and honey-fried licorice root.Chinese medicine provided by the invention is single-minded to be directed to liver cancer caused by the chronic hepatitis B cause of disease, has stronger practicality and actuality；This Chinese medicine preparation using action temperature and, through experiment and it is clinical confirm to drop enzyme by certain protect liver and form with improving immunity and improving the Chinese medicine of symptom and sign curative effect, effect is more reliable, stronger the effect of to liver cancer companion's Chronic Hepatitis B, while side effect is less；This Chinese medicine can effectively extend patient survival, and clinical symptoms are for example weak, receive poor, hepatalgia, Nausea and vomiting, jaundice etc. by improving, and improve the quality of life of patient.
Description
Technical field
The invention belongs to tcm field, and in particular to a kind of to treat Chinese medicine of the liver cancer with chronic hepatitis B.
Background technology
Primary carcinoma of liver (abbreviation liver cancer) is very common in China, and liver cancer number is newly sent out up to 300,000 every year by China according to statistics
People, the people of number of dying of illness about 250,000, this causes huge loss to the life and property of China people.Although the reason for causing liver cancer
A lot, such as hepatitis B (HBV) and hepatitis C virus (HCV), aflatoxin, drinking water pollution, ethanol.However, there are data
Show, it is relevant with viral (HBV) persistent infection of chronic hepatitis B that more than 90% its cause of disease is there are about in China's liver cancer patient.
The complicated clinical of liver cancer, the normal asymptomatic or symptom unobvious of early liver cancer, even if the disease of mid and late liver cancer
Shape is also easily covered by the symptom of chronic hepatitis B and hepatic sclerosis.Chronic hepatitis B is the liver chronic inflammation as caused by HBV, and the course of disease is more
More than half a year, or some morbidity's date unknowns are true, but subtract with the sings and symptoms of chronic hepatitis, such as weak, appetite
Move back, nausea, abdominal distension, hepatalgia etc.；Body, which is looked into, can hepatomegaly, splenomegaly, and quality is medium hardness, the light tenderness in hepatic region；The state of an illness is heavier
Person can exception or persistent anomaly with chronic liver disease face, spider angioma, liver palms, splenomegaly, liver function.Chronic hepatitis B is according to clinic
State of an illness weight can be divided into slight, moderate and severe.
Treatment on liver cancer with chronic hepatitis B, clinically to focus on liver cancer, especially surgery, radiotherapy department, ablation in itself more
The doctor of the section office such as refrigerating chamber, chemotherapy section, Invasive Technology Department, in terms of typically having focused on liver cancer lump, such as surgery excision lump,
Interventional embolization lump, ablation or freezing lump etc., many methods have the side effect of larger wound, especially liver cancer chemotherapy
It is larger, or even serious hepatic disorder, serious gastrointestinal reaction can be caused, or even hepatitis B virus recurrence, liver cancer recurrence, liver can be made
MSOF, the state of an illness is worsened and threat to life.Therefore, while liver cancer itself is paid attention to, chronic should also be paid much attention to
The problem of liver, although the chronic hepatitis B state of an illness itself may not weigh, the recurrence of the quality of life, liver cancer of patient can be related to
Rate height and lifetime problem.
The medicine of chronic hepatitis B can be divided into antiviral agent, liver protection medicine and immunomodulator etc..Antiviral drugs
Mainly there are interferons and nucleosides (acid) class, the former includes plain interferon a (2a, 2b and 1b) and glycol interferon a
(2a and 2b)；The latter includes such as 5 kinds of Lamivudine, adefovirdipivoxil, Sebivo, Entecavir and tenofovir；Treat liver
The medicine of cancer also has a variety of (including targeted drugs).However, up to the present, still belong to specific medicament, liver cancer without a kind of medicine
Year recurrence rate still reach more than 30%~50%, the life cycle of serious threat liver cancer patient.
The Chinese patent drug or Chinese medicine preparation of existing disclosed treatment liver cancer, typically refer to all liver cancer or a variety of cancers
Disease such as lung cancer, tumor in digestive tract, kidney etc. and kinds cancer cause metastatic hepatic carcinoma, it is well known that liver caused by chronic hepatitis B
Cancer, on the one hand very universal in China, the incidence of disease is very high, almost accounts for 90% or so of China's liver cancer sum；The opposing party
Face, liver cancer caused by chronic hepatitis B, with other reasons liver cancer as caused by drinking water pollution, ethanol etc. in its treatment and prognosis etc.
Aspect has obvious difference, as long as liver cancer caused by general non-hepatitis B eliminates lump, removes the cause of disease, cause virus replication or
For the probability that liver function is seriously damaged with regard to smaller, prognosis may also be much better.However, existing disclosed matching somebody with somebody for liver cancer
Side's (Chinese patent drug), otherwise Chinese medicine is relatively simple, as huaier granules (being made up of locust tree microellobosporia), cinobufagin (suppressed by toad skin and
Into), lentinan film (by mushroom refine form), the cancer that disappears put down (CAULIS MARSDENIAE TENACISSIMAE is made)；By a small number of a few herbs and wherein must
It is made up of one or two kinds of virose Chinese medicines, such as：Cantharides capsule (containing Chinese blister beetle), Jinlong capsule are (white containing fresh house lizard, fresh money
Flower snake, fresh long-nosed pit viper etc.), gan fu le (containing ground bettle etc.) etc..It is known that liver cancer is more complicated (many with the state of an illness of chronic hepatitis B
Patient can be with different degrees of hepatic sclerosis even liver ascites), can have a variety of different pathology and performance, therefore, Dan Conggai
For kind clinical symptoms and sign, a kind of single Chinese medicine can not possibly solve a variety of symptoms, moreover, to liver cancer and chronic
For liver, it is also can not possibly have stronger antitumaous effect that any Chinese medicine, which includes poisonous Chinese herbal medicine,.It is existing it is poisonous in
Herbal medicine is very little to the inhibitory action of cancer cell in vivo.And the method really with suppression growth of cancer cells is raising machine
The immunity and killing cancer cell of body or the T killing cells and its cell factor for suppressing cancer cell.Therefore, existing Chinese patent medicine for resisting cancer
Formula is not specific drug or perfect formula yet.
Therefore, needing a kind of specific aim Chinese medicine badly can safeguard that the liver function of liver cancer companion's Chronic Hepatitis B is stable, reduce liver
Cancer recurrence and the life cycle for improving liver cancer companion's Chronic Hepatitis B, while reduce side effect, improve people's living standard.
The content of the invention
An object of the present invention is to solve above-mentioned existing issue, there is provided a kind of liver cancer for the treatment of is with chronic hepatitis B
Medicine, the Chinese medicine are directed to liver cancer caused by the chronic hepatitis B cause of disease, and validity is stronger, and toxic side effect is small, can effectively extend patient's
Life cycle.
A kind of medicinal material treated Chinese medicine of the liver cancer with chronic hepatitis B, include following parts by weight provided by the invention：
11~19 parts of radix pseudostellariae, 16~24 parts of the Radix Astragali, 11~19 parts of arillus longan, 11~19 parts of Poria cocos, 11~19 parts of Chinese yam,
11~19 parts of Canton love-pea vine, 20~29 parts of oldenlandia diffusa, 16~24 parts of Sculellaria barbata, 11~19 parts of radix bupleuri, 8~16 parts of oriental wormwood, five
11~19 parts of taste, 16~24 parts of coix seed, 11~19 parts of turtle shell, 6~14 parts of rhizoma alismatis, 6~14 parts of corydalis tuber, the fruit of Chinese wolfberry 11~
19 parts, 6~14 parts of the membrane of a chicken's gizzard, 6~14 parts of jujube, 3~9 parts of honey-fried licorice root.
Further, a kind of medicine treated Chinese medicine of the liver cancer with chronic hepatitis B, include following parts by weight provided by the invention
Material：
13~17 parts of radix pseudostellariae, 18~22 parts of the Radix Astragali, 13~17 parts of arillus longan, 13~17 parts of Poria cocos, 13~17 parts of Chinese yam,
13~17 parts of Canton love-pea vine, 22~27 parts of oldenlandia diffusa, 18~22 parts of Sculellaria barbata, 13~17 parts of radix bupleuri, 10~14 parts of oriental wormwood, five
13~17 parts of taste, 18~22 parts of coix seed, 13~17 parts of turtle shell, 8~12 parts of rhizoma alismatis, 8~12 parts of corydalis tuber, the fruit of Chinese wolfberry 13~
17 parts, 8~12 parts of the membrane of a chicken's gizzard, 8~12 parts of jujube, 4~8 parts of honey-fried licorice root.
Further, a kind of Chinese medicine for treating liver cancer companion's chronic hepatitis B provided by the invention, including following parts by weight
Medicinal material：
15 parts of radix pseudostellariae, 20 parts of the Radix Astragali, 15 parts of arillus longan, 15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of Canton love-pea vine, oldenlandia
Grass 25 parts, 20 parts of Sculellaria barbata, 15 parts of radix bupleuri, 12 parts of oriental wormwood, 15 parts of the fruit of Chinese magnoliavine, 20 parts of coix seed, 15 parts of turtle shell, 10 parts of rhizoma alismatis,
10 parts of corydalis tuber, 15 parts of the fruit of Chinese wolfberry, 10 parts of the membrane of a chicken's gizzard, 10 parts of jujube, 6 parts of honey-fried licorice root.
Wherein, the preprocess method of above-mentioned turtle shell is：First turtle shell is smashed plus water 300mL is decocted first 5~10min, is added water
In right amount with it is other be medicine with decocting.Turtle shell life is strong with enriching yin power, and vinegar processs the work(that can strengthen dissipating bind, thus our Chinese medicine using softening and resolving hard mass as
It is main, with vinegar turtle shell more preferably.
The beneficial effects of the present invention are：Chinese medicine provided by the invention is single-minded to be directed to liver cancer caused by the chronic hepatitis B cause of disease,
With stronger practicality and actuality；This Chinese medicine preparation using action temperature and, through experiment and clinical confirm there is certain protect liver
Enzyme drops and with improving immunity and improving the Chinese medicine composition of symptom and sign curative effect, effect is more reliable, to liver cancer with chronic hepatitis B
The effect of patient, is stronger, while side effect is less；This Chinese medicine can effectively extend patient survival, for example weary by improving clinical symptoms
Power, receive poor, hepatalgia, Nausea and vomiting, jaundice etc., improve the quality of life of patient.
Embodiment
Present disclosure is described in detail below in conjunction with specific embodiment.It should be noted that retouched in following embodiments
The combination of the technical characteristic or technical characteristic stated is not construed as isolated, and they can be mutually combined so as to reach
Superior technique effect.
Embodiment 1
1st, the Chinese medicine preparation that the present embodiment uses is as follows：
15 parts of radix pseudostellariae, 20 parts of the Radix Astragali, 15 parts of arillus longan, 15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of Canton love-pea vine, oldenlandia
Grass 25 parts, 20 parts of Sculellaria barbata, 15 parts of radix bupleuri, 12 parts of oriental wormwood, 15 parts of the fruit of Chinese magnoliavine, 20 parts of coix seed, 15 parts of turtle shell, 10 parts of rhizoma alismatis,
10 parts of corydalis tuber, 15 parts of the fruit of Chinese wolfberry, 10 parts of the membrane of a chicken's gizzard, 10 parts of jujube, 6 parts of honey-fried licorice root.
2nd, usage and the course for the treatment of are as follows：
Daily 1 dose, add 700mL decoctings to 200~250mL, it is warm at twice to drink.It is used in conjunction 8 days, rests 2 days, then with 10 days.
Each course for the treatment of is 20 days, and 3~4 courses for the treatment of are used in conjunction.
Embodiment 2
1st, the Chinese medicine preparation that the present embodiment uses is as follows：
14 parts of radix pseudostellariae, 19 parts of the Radix Astragali, 14 parts of arillus longan, 14 parts of Poria cocos, 14 parts of Chinese yam, 14 parts of Canton love-pea vine, oldenlandia
24 parts of grass, 19 parts of Sculellaria barbata, 14 parts of radix bupleuri, 11 parts of oriental wormwood, 14 parts of the fruit of Chinese magnoliavine, 19 parts of coix seed, 14 parts of turtle shell, 9 parts of rhizoma alismatis, prolong
9 parts of Hu rope, 14 parts of the fruit of Chinese wolfberry, 9 parts of the membrane of a chicken's gizzard, 9 parts of jujube, 5 parts of honey-fried licorice root.
2nd, usage and the course for the treatment of are as follows：
1 dose every mouthful, add 700mL decoctings to 200~250mL, it is warm at twice to drink.It is used in conjunction 8 days, rests 2 days, then with 10 days.
Each course for the treatment of is 20 days, and 3~4 courses for the treatment of are used in conjunction.
Embodiment 3
1st, the Chinese medicine preparation that the present embodiment uses is as follows：
16 parts of radix pseudostellariae, 21 parts of the Radix Astragali, 16 parts of arillus longan, 16 parts of Poria cocos, 16 parts of Chinese yam, 16 parts of Canton love-pea vine, oldenlandia
26 parts of grass, 21 parts of Sculellaria barbata, 16 parts of radix bupleuri, 13 parts of oriental wormwood, 16 parts of the fruit of Chinese magnoliavine, 21 parts of coix seed, 16 parts of vinegar turtle shell, rhizoma alismatis 11
Part, 11 parts of corydalis tuber, 16 parts of the fruit of Chinese wolfberry, 11 parts of the membrane of a chicken's gizzard, 11 parts of jujube, 7 parts of honey-fried licorice root.
2nd, usage and the course for the treatment of are as follows：
Daily 1 dose, add 700mL decoctings to 200~250mL, it is warm at twice to drink.It is used in conjunction 8 days, rests 2 days, then with 10 days.
Each course for the treatment of is 20 days, and 3~4 courses for the treatment of are used in conjunction.
Compliance test result
With out-patient, 60 are investigation object, give medicine of the present invention and are treated, and patient takes 1 dose of Chinese medicine daily,
It is continuous to take 40 days to investigate the time limit, investigate the effect of this Chinese medicine is to liver cancer companion's chronic hepatitis B.
Efficacy assessment standard is divided into effective and invalid two kinds of situations, as a result such as table 1.
The effect of 1 Chinese medicine of table is to liver cancer companion's chronic hepatitis B statistical form
| Case load | Treatment time/day | Effective number of cases | Invalid number of cases | It is efficient |
| 60 | 40 | 55 | 5 | 91.7% |
From the data in table 1, during treatments in 40 days of investigation, with 60 patients of drug therapy of the present invention,
There are 55 with therapeutic effect, treated effect reaches 91.7%.
Although having been presented for some embodiments of the present invention herein, it will be appreciated by those of skill in the art that
Without departing from the spirit of the invention, the embodiments herein can be changed.Above-described embodiment be it is exemplary, no
Restriction that should be using the embodiments herein as interest field of the present invention.
Claims (5)
1. a kind of treat Chinese medicine of the liver cancer with chronic hepatitis B, it is characterised in that is made up of the medicinal material of following parts by weight：
11~19 parts of radix pseudostellariae, 16~24 parts of the Radix Astragali, 11~19 parts of arillus longan, 11~19 parts of Poria cocos, 11~19 parts of Chinese yam, chicken bone
11~19 parts of grass, 20~29 parts of oldenlandia diffusa, 16~24 parts of Sculellaria barbata, 11~19 parts of radix bupleuri, 8~16 parts of oriental wormwood, the fruit of Chinese magnoliavine
11~19 parts, 16~24 parts of coix seed, 11~19 parts of turtle shell, 6~14 parts of rhizoma alismatis, 6~14 parts of corydalis tuber, the fruit of Chinese wolfberry 11~19
Part, 6~14 parts of the membrane of a chicken's gizzard, 6~14 parts of jujube, 3~9 parts of honey-fried licorice root.
2. a kind of Chinese medicine for treating liver cancer companion's chronic hepatitis B as claimed in claim 1, it is characterised in that by following parts by weight
Medicinal material forms：
13~17 parts of radix pseudostellariae, 18~22 parts of the Radix Astragali, 13~17 parts of arillus longan, 13~17 parts of Poria cocos, 13~17 parts of Chinese yam, chicken bone
13~17 parts of grass, 22~27 parts of oldenlandia diffusa, 18~22 parts of Sculellaria barbata, 13~17 parts of radix bupleuri, 10~14 parts of oriental wormwood, the fruit of Chinese magnoliavine
13~17 parts, 18~22 parts of coix seed, 13~17 parts of turtle shell, 8~12 parts of rhizoma alismatis, 8~12 parts of corydalis tuber, the fruit of Chinese wolfberry 13~17
Part, 8~12 parts of the membrane of a chicken's gizzard, 8~12 parts of jujube, 4~8 parts of honey-fried licorice root.
3. a kind of Chinese medicine for treating liver cancer companion's chronic hepatitis B as claimed in claim 2, it is characterised in that by following parts by weight
Medicinal material forms：
15 parts of radix pseudostellariae, 20 parts of the Radix Astragali, 15 parts of arillus longan, 15 parts of Poria cocos, 15 parts of Chinese yam, 15 parts of Canton love-pea vine, oldenlandia diffusa 25
Part, 20 parts of Sculellaria barbata, 15 parts of radix bupleuri, 12 parts of oriental wormwood, 15 parts of the fruit of Chinese magnoliavine, 20 parts of coix seed, 15 parts of turtle shell, 10 parts of rhizoma alismatis, prolong recklessly
10 parts of rope, 15 parts of the fruit of Chinese wolfberry, 10 parts of the membrane of a chicken's gizzard, 10 parts of jujube, 6 parts of honey-fried licorice root.
A kind of 4. Chinese medicine for treating liver cancer companion's chronic hepatitis B as described in claims 1 to 3 any one, it is characterised in that institute
It is vinegar turtle shell to state turtle shell.
A kind of 5. Chinese medicine for treating liver cancer companion's chronic hepatitis B as described in claims 1 to 3 any one, it is characterised in that institute
The pretreatment for stating turtle shell is first to be smashed to add water 300mL to decoct 5~10min, is added water appropriate same pan-fried with other Chinese medicines.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510247259.0A CN104840813B (en) | 2015-05-15 | 2015-05-15 | It is a kind of to treat Chinese medicine of the liver cancer with chronic hepatitis B |
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| CN201510247259.0A CN104840813B (en) | 2015-05-15 | 2015-05-15 | It is a kind of to treat Chinese medicine of the liver cancer with chronic hepatitis B |
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| CN104840813A CN104840813A (en) | 2015-08-19 |
| CN104840813B true CN104840813B (en) | 2017-12-15 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129945A (en) * | 2007-08-29 | 2008-02-27 | 尹克山 | Traditional Chinese medicine for treating diffuse liver cancer |
| CN103893481A (en) * | 2014-03-28 | 2014-07-02 | 陈林豪 | Traditional Chinese medicine watered pill preparation for treating intermediated or advanced-staged liver cancer |
-
2015
- 2015-05-15 CN CN201510247259.0A patent/CN104840813B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129945A (en) * | 2007-08-29 | 2008-02-27 | 尹克山 | Traditional Chinese medicine for treating diffuse liver cancer |
| CN103893481A (en) * | 2014-03-28 | 2014-07-02 | 陈林豪 | Traditional Chinese medicine watered pill preparation for treating intermediated or advanced-staged liver cancer |
Non-Patent Citations (1)
| Title |
|---|
| 化疗结合逍遥散加减治疗原发性肝癌24例临床观察;熊建利;《中医药导报》;20110228;第17卷(第02期);18-20 * |
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| CN104840813A (en) | 2015-08-19 |
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