CN104840789A - Hypotensive composition - Google Patents
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- CN104840789A CN104840789A CN201510248834.9A CN201510248834A CN104840789A CN 104840789 A CN104840789 A CN 104840789A CN 201510248834 A CN201510248834 A CN 201510248834A CN 104840789 A CN104840789 A CN 104840789A
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Abstract
The invention relates to the technical field of traditional Chinese medicine, in particular to a hypotensive composition. The composition comprises the following ingredients in parts by mass: 20 to 25 parts of sticktight, 8 to 15 parts of celery roots, 8 to 20 parts of peanut herbs, 10 to 24 parts of polygonum multiflorum, 10 to 25 parts of liquorice, 4 to 8 parts of achyranthes bidentata, 2 to 6 parts of corn stigma, 2 to 6 parts of mulberry leaves and 2 to 4 parts of bulbus fritillariae cirrhosae. The hypotensive composition has the beneficial effects that 1, the hypotensive composition has the effects of calming the liver wind and relieving the peripheral artery spasm, so that excessive qi and blood reduction is realized, the hypotensive goal is achieved, when the hypotensive composition is used for treating hypertension, the goals of good curative effect and no side effect are achieved, and the used raw medicine is cheap and can be easily obtained; 2, the hypotensive composition has the functions of clearing the heat, calming the liver, dissipating phlegm and activating blood circulation, and is mainly used for hypertension and hyperlipidemia, the production process is simple, the raw materials can be easily obtained, the hypotensive composition can be made into various medicine preparations, and the hypotensive composition belongs to pure traditional medicine composite medicine with the advantages that the curative effect is exact, safety and convenience are realized, the side effect is small, and the price is low.
Description
Technical field
The present invention relates to technical field of Chinese medicines, especially a kind of compositions of blood pressure lowering.
Background technology
Hypertension (hypertensivedisease) is the disease of lasting hyperpiesia, the diseases such as apoplexy, heart disease, hemangioma, renal failure can be caused, hypertension be a kind of with arterial pressure rising for feature, can with the systemic disease of the functional or organic change of heart, blood vessel, brain and kidney and other organs, it have essential hypertension and secondary hypertension point.Do not using in antihypertensive situation, the systolic pressure >=139mmHg of a people and/or diastolic pressure >=89mmHg, just belongs to hypertension.
For hypertension, doctor trained in Western medicine and the traditional Chinese medical science have the medicine of blood pressure lowering.The Western medicine of blood pressure lowering has Nifedipine sustained release tablets, YM-09730-5 slow releasing tablet, FUFANG LUOBUMA PIAN, compound recipe reserpine etc.Because Western medicine blood pressure lowering is all based on blood vessel dilating, and blood vessel dies down at continuous process of expansion Elastic and hardens, and therefore makes the people of life-time service depressor easily cause sclerosis of blood vessels and break, and causes the disease such as cerebral vessels embolism, apoplexy.Therefore, Western medicine is not suitable for permanent use.
Pharmaceutical formulation for blood pressure lowering in Chinese medicine is a lot, relevant Chinese patent application part has: No. 200810132686.4 " one treats hypertensive Chinese medicine composition ", No. 201010186118.X " one treats hypertensive Chinese medicine composition and preparation method thereof " and No. 201010270380.2 " Chinese medicine preparation for the treatment of diabetes with hypertension " etc., all disclose the medicine that some utilize Chinese crude drug to prepare, their curative effect there is no report.
Summary of the invention
The technical problem to be solved in the present invention is: overcome deficiency of the prior art, and provide a kind of therapeutic effect clear and definite, effective, speed is fast, the compositions of the blood pressure lowering had no side effect.
For solving the problems of the technologies described above, the technical solution used in the present invention is as follows:
A compositions for blood pressure lowering, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part.
Further, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 22-28 part, root of Herba Apii graveolentis 10-12 part, Semen arachidis hypogaeae herb 10-18 part, Radix Polygoni Multiflori 12-20 part, Radix Glycyrrhizae 12-24 part, Radix Achyranthis Bidentatae 5-7 part, Stigma Maydis 3-5 part, Folium Mori 3-5 part, Bulbus Fritillariae Cirrhosae 2.2-3.8 part.
Further, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 25 parts, root of Herba Apii graveolentis 11 parts, Semen arachidis hypogaeae herb 14 parts, Radix Polygoni Multiflori 16 parts, 16 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 6 parts, Stigma Maydis 4 parts, 4 parts, Folium Mori, Bulbus Fritillariae Cirrhosae 3 parts.
Prepare a method for right blood pressure reducing composition, said method comprising the steps of: take each composition according to proportioning, with alcohol reflux, filter, filtrate concentrates, dry, obtains desired composition.
Further, said method comprising the steps of: take composition according to proportioning, with alcohol reflux 2-3 time, add the ethanol of the 50-85% of 8-12 times of medical material weight at every turn, each extraction time is 3-6h, filters, merging filtrate, fling to ethanol, dry, obtain desired composition.
A kind of blood pressure reducing composition, the mass parts of described compositions is composed as follows: the one composition in the composition of Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part and following weight portion: bitter golden basin 8-15 part, Herb Gynostemmae Pentaphylli 2-6 part, Cortex Eucommiae 2-6 part.
Further, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part, bitter golden basin 8-15 part.
Further, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 25, root of Herba Apii graveolentis 12 parts, Semen arachidis hypogaeae herb 14 parts, Radix Polygoni Multiflori 16 parts, 18 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 6 parts, Stigma Maydis 4 parts, 4 parts, Folium Mori, Bulbus Fritillariae Cirrhosae 3 parts, bitter 12 parts, golden basin.
The object of adding Herba Bidentis Bipinnatae in the present invention is: Herba Bidentis Bipinnatae has heat-clearing and toxic substances removing, the effect of promoting blood circulation to remove blood stasis, has effect significantly at treatment essential hypertension, and has significantly reduction cholesterol effect, clothes of a specified duration effectively can suppress the formation of cerebral thrombosis, are a kind of good medicine preventing cardiovascular and cerebrovascular vessel.
The beneficial effect of technical scheme of the present invention is adopted to be:
1, the compositions of blood pressure lowering of the present invention has suppressing the hyperactive liver to relieve the wind syndrome, alleviate effect of periphery arteriolospasm, thus the QI and blood of containing was declined, reach the object of blood pressure lowering, the object can play good effect for hypertensive treatment, having no side effect, and raw materials used medicine is all cheap and easy to get.
2, the present invention has heat clearing away suppressing the hyperactive liver, and the function of invigorating blood circulation of reducing phlegm, is mainly used in hypertension, hyperlipidemia, production technology is simple, raw material is easy, can make various medicinal acute, is little, the cheap pure traditional Chinese compound medicine of a kind of determined curative effect, safe ready, side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
A compositions for blood pressure lowering, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part.
The mass parts composition of embodiment 1-5 is in table 1.
| Raw material | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 |
| Herba Bidentis Bipinnatae | 20 | 22 | 25 | 28 | 30 |
| Root of Herba Apii graveolentis | 8 | 10 | 11 | 12 | 15 |
| Semen arachidis hypogaeae herb | 8 | 10 | 14 | 18 | 20 |
| Radix Polygoni Multiflori | 10 | 12 | 14 | 20 | 24 |
| Radix Glycyrrhizae | 10 | 12 | 16 | 24 | 25 |
| Radix Achyranthis Bidentatae | 4 | 5 | 6 | 7 | 8 |
| Stigma Maydis | 2 | 3 | 4 | 5 | 6 |
| Folium Mori | 2 | 3 | 4 | 5 | 6 |
| Bulbus Fritillariae Cirrhosae | 2 | 2.2 | 3 | 3.8 | 4 |
Table 1
Preparation method comprises the following steps: take composition according to proportioning, with alcohol reflux 2-3 time, adds the ethanol of the 50-85% of 8-12 times of medical material weight at every turn, each extraction time is 3-6h, filters, merging filtrate, fling to ethanol, dry, obtain desired composition.
The mass parts composition of embodiment 6-17 is in table 2.
| Raw material | Embodiment 6 | Embodiment 7 | Embodiment 8 | Embodiment 9 | Embodiment 10 | Embodiment 11 |
| Herba Bidentis Bipinnatae | 20 | 30 | 20 | 30 | 20 | 30 |
| Root of Herba Apii graveolentis | 8 | 15 | 8 | 15 | 8 | 15 |
| Semen arachidis hypogaeae herb | 8 | 20 | 8 | 20 | 8 | 20 |
| Radix Polygoni Multiflori | 10 | 24 | 10 | 24 | 10 | 24 |
| Radix Glycyrrhizae | 10 | 25 | 10 | 25 | 10 | 25 |
| Radix Achyranthis Bidentatae | 4 | 8 | 4 | 8 | 4 | 8 |
| Stigma Maydis | 2 | 6 | 2 | 6 | 2 | 6 |
| Folium Mori | 2 | 6 | 2 | 6 | 2 | 6 |
| Bulbus Fritillariae Cirrhosae | 2 | 4 | 2 | 4 | 2 | 4 |
| Bitter golden basin | 8 | 15 | - | - | - | - |
| Herb Gynostemmae Pentaphylli | - | - | 2 | 6 | - | - |
| The Cortex Eucommiae | - | - | - | - | 2 | 6 |
Table 2
Preferred embodiment 12-14 is in table 3.
| Raw material | Embodiment 12 | Embodiment 13 | Embodiment 14 |
| Herba Bidentis Bipinnatae | 20 | 25 | 30 |
| Root of Herba Apii graveolentis | 8 | 12 | 15 |
| Semen arachidis hypogaeae herb | 8 | 14 | 20 |
| Radix Polygoni Multiflori | 10 | 16 | 24 |
| Radix Glycyrrhizae | 10 | 18 | 25 |
| Radix Achyranthis Bidentatae | 4 | 6 | 8 |
| Stigma Maydis | 2 | 4 | 6 |
| Folium Mori | 2 | 4 | 6 |
| Bulbus Fritillariae Cirrhosae | 2 | 3 | 4 |
| Bitter golden basin | 8 | 12 | 15 |
Table 3
Adopt the Chinese medicine composition that above technical recipe is made, through Duo Jia hospital to 300 routine hyperpietic's clinical practices, potion on the one, potion is divided into be taken for twice, within 15 days, is a course for the treatment of.300 routine patients are divided into matched group and treatment group two groups at random, diagnostic criteria: systolic pressure is equal to or higher than 160mmHg (21.3kPa), and diastolic pressure is equal to or higher than 95mmHg (12.721.3kPa), and both have 1 through examining, and can make a definite diagnosis.
Criterion of therapeutical effect according in " new Chinese medicine clinical guidance principle (first volume) ":
Effective: 1. more than diastolic pressure decline 10mmHg (1.3kPa), and reach normal range; Though 2. diastolic pressure is normally not near, with decline 20mmHg (2.7kPa) or more, wherein 1 must be possessed;
Effective: 1. diastolic pressure declines not as good as 10mmHg (1.3kPa), but reaches normal range; 2. diastolic pressure comparatively treats the front 10 ~ 19mmHg (1.3 ~ 2.5kPa) that declines, but does not reach normal range; 3. systolic pressure comparatively treats front decline 30mmHg (4kPa); Wherein 1 must be possessed;
Invalid: not reach above standard.
After two groups of cases treat two courses for the treatment of, comparitive study the results are shown in Table 4.
| Group | Number of cases | Effective number | Significant figure | Invalid number | Total effective rate |
| Treatment group | 150 | 115 | 25 | 10 | 93.33％ |
| Matched group | 150 | 98 | 2 | 50 | 66.67％ |
Table 4
Compositions safety detection:
The quality inspection standard of the provincial Chinese crude drug issued according to Ministry of Public Health detects hypoglycemic compositions of the present invention, test item: (1) content of beary metal, (2) chloride, sulphates content, (3) arsenic salt etc., testing result all meets the requirements, relievedly can take, and do not have Tu Fu to act on to human body, can relievedly eat.
Although above-described embodiment describes in detail technical scheme of the present invention, but technical scheme of the present invention is not limited to above embodiment, when not departing from thought of the present invention and aim, claims limited range of the present invention all will be fallen into any change that technical scheme of the present invention is done.
Claims (8)
1. the compositions of a blood pressure lowering, it is characterized in that, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part.
2. a kind of blood pressure reducing composition according to claim 1, is characterized in that: the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 22-28 part, root of Herba Apii graveolentis 10-12 part, Semen arachidis hypogaeae herb 10-18 part, Radix Polygoni Multiflori 12-20 part, Radix Glycyrrhizae 12-24 part, Radix Achyranthis Bidentatae 5-7 part, Stigma Maydis 3-5 part, Folium Mori 3-5 part, Bulbus Fritillariae Cirrhosae 2.2-3.8 part.
3. a kind of blood pressure reducing composition according to claim 1, it is characterized in that, the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 25 parts, root of Herba Apii graveolentis 11 parts, Semen arachidis hypogaeae herb 14 parts, Radix Polygoni Multiflori 16 parts, 16 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 6 parts, Stigma Maydis 4 parts, 4 parts, Folium Mori, Bulbus Fritillariae Cirrhosae 3 parts.
4. prepare a method for the blood pressure reducing composition according to any one of claim 1-3, it is characterized in that, said method comprising the steps of: take each composition according to proportioning, with alcohol reflux, filter, filtrate concentrates, dry, obtains desired composition.
5. a kind of method preparing blood pressure reducing composition according to claim 4, it is characterized in that, said method comprising the steps of: take composition according to proportioning, with alcohol reflux 2-3 time, add the ethanol of the 50-85% of 8-12 times of medical material weight at every turn, each extraction time is 3-6h, filter, merging filtrate, flings to ethanol, drying, obtains desired composition.
6. a blood pressure reducing composition, it is characterized in that, the mass parts of described compositions is composed as follows: the one composition in the composition of Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part and following weight portion: bitter golden basin 8-15 part, Herb Gynostemmae Pentaphylli 2-6 part, Cortex Eucommiae 2-6 part.
7. a kind of blood pressure reducing composition according to claim 6, is characterized in that: the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 20-30 part, root of Herba Apii graveolentis 8-15 part, Semen arachidis hypogaeae herb 8-20 part, Radix Polygoni Multiflori 10-24 part, Radix Glycyrrhizae 10-25 part, Radix Achyranthis Bidentatae 4-8 part, Stigma Maydis 2-6 part, Folium Mori 2-6 part, Bulbus Fritillariae Cirrhosae 2-4 part, bitter golden basin 8-15 part.
8. a kind of blood pressure reducing composition according to claim 6, is characterized in that: the mass parts of described compositions is composed as follows: Herba Bidentis Bipinnatae 25, root of Herba Apii graveolentis 12 parts, Semen arachidis hypogaeae herb 14 parts, Radix Polygoni Multiflori 16 parts, 18 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 6 parts, Stigma Maydis 4 parts, 4 parts, Folium Mori, Bulbus Fritillariae Cirrhosae 3 parts, bitter 12 parts, golden basin.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106214985A (en) * | 2016-08-16 | 2016-12-14 | 蒋安为 | Traditional Chinese medicine for treating hypertension |
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| EP1186297A2 (en) * | 2000-09-05 | 2002-03-13 | Kao Corporation | Agent for preventing, improving or treating hypertension |
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| CN106214985A (en) * | 2016-08-16 | 2016-12-14 | 蒋安为 | Traditional Chinese medicine for treating hypertension |
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Application publication date: 20150819 |