CN104815313A - Decoction medicine for treating behcet's syndrome and preparation method thereof - Google Patents

Abstract

The invention discloses a decoction medicine for treating behcet's syndrome and a preparation method thereof. The decoction medicine respectively comprises the following components in parts by mass: 1-3 parts of raw licorice root, 1-3 parts of Sichuan coptis root, 1-3 parts of baikal skullcap root, 1-3 parts of dried ginger, 1-3 parts of Chinese date and 1-3 parts of processed pinellia tuber. The preparation method of the medicine comprises the following steps: selectively purchasing highly-qualified and clean first-grade raw licorice root, Sichuan coptis root, baikal skullcap root, dried ginger, Chinese date and processed pinellia tuber according to the mass part ratio, and respectively grinding into granules for later use; and filling ground granular medicines into a cloth bag, then tying the bag opening, soaking into cold boiled water for about half an hour by taking the degree of penetrating medicine tissues as the standard, then putting the soaked medicines into a medicine decocting machine, adding cold boiled water of which the water level is 33mm higher than the medicine surface, decocting for 35 minutes by using strong fire firstly and using slow fire secondly, decocting with water twice, filtering residues, mixing and concentrating to obtain 1080ml of 50% traditional Chinese medicine liquid, bagging and sealing, and then putting into a refrigerator for refreshing for later use.

Description

A kind of decoction medicine for the treatment of Behcet's syndrome and preparation method thereof

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of decoction medicine for the treatment of Behcet's syndrome, particularly for the field of the decoction medicine and preparation method thereof of mankind's Behcet's syndrome patient.

Background technology

Show according to medical literature data, behcet syndrome is also known as Behcet disease, it is a kind of general immune system disease, belong to vasculitic one, it can encroach on the multiple organ of human body, comprise oral cavity, skin, articular muscle, eyes, blood vessel, heart, lung and nervous system etc., main manifestations is repeatedly oral cavity and perineal position ulcer, erythra, lower limb erythema nodosa, eye iritis, esophageal ulcer, small intestinal or colonic ulcer and arthralgia etc., behcet syndrome needs the Drug therapy of rule, comprise the medicine of various immunity moderation, do not treat then prognosis bad, severe patient threat to life.

The traditional Chinese medical science is thought: the disease of cari oris mucosa is many because of internal injury caused by excess of seven emotions, ferritic is weak, the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, cause hot and suffocating, hyperactivity of deficient fire is stifling and send out, as " conscience has heat, normal trouble aphtha " (" medical secrets of official "), " aphtha person, conscience has heat, gas rushes to Jiao, a smoked dispute, pretend skin ulcer also ", " stomach-QI being weak, essence derived from food is few, empty sun is above sent out and is aphtha " (" Shengji Zonglu "), the Ming Dynasty expands imperial physician Xue controlling court and in its " ability to speak class is wanted ", mentions " aphtha part of the body cavity above the diaphragm housing the heart and lungs excess-heat, deficiency-cold in middle-JIAO, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels YIN-fire, individual caused by the change of disease, when controlling it respectively ", the vital organs of the human body of the diseases of oral mucosa such as visible oral ulcer and people have substantial connection.

So, just how finding a kind of Chinese herbal medicine effectively can treating above-mentioned Behcet's syndrome, is our current problem in urgent need to solve.

Summary of the invention

The object of this invention is to provide a kind of decoction medicine for the treatment of Behcet's syndrome and preparation method thereof, to solve the problem of Behcet's syndrome patient early recovery.This medicine is that have compatibility science, the efficacy of a drug is powerful, hit pathogenesis, has fully demonstrated dispersing the stagnated pathogen with pungent drugs and lowering the adverse QI with bitter drugs, the Therapeutic Principle that Qinghua is damp and hot with common Chinese herbal medicine for raw material.

For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of decoction medicine for the treatment of Behcet's syndrome, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Glycyrrhizae 1-3 part;

Rhizoma Coptidis 1-3 part;

Radix Scutellariae 1-3 part;

Rhizoma Zingiberis 1-3 part;

Fructus Jujubae 1-3 part;

Rhizoma Pinelliae Preparata 1-3 part.

According to the decoction medicine for the treatment of Behcet's syndrome provided by the present invention, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Glycyrrhizae 1 part;

Rhizoma Coptidis 1 part;

Radix Scutellariae 1 part;

Rhizoma Zingiberis 1 part;

1 part, Fructus Jujubae;

Rhizoma Pinelliae Preparata 1 part.

A kind of decoction medicine for the treatment of Behcet's syndrome and preparation method thereof, is characterized in that, described method comprises the steps:

A, choose the clean one-level Radix Glycyrrhizae of high-quality 1 part, Rhizoma Coptidis 1 part, Radix Scutellariae 1 part, Rhizoma Zingiberis 1 part, 1 part, Fructus Jujubae, Rhizoma Pinelliae Preparata 1 part, be ground into graininess respectively stand-by;

B, by the granular medicament splendid attire that crushes after tying in cloth bag, soak half an hour in cold boiled water about, with osmotic drug degree of being organized as, then more soaked medicine is put in boiling machine, added the cold boiled water of medicine 33mm, fried 35 minutes of first intense fire, rear slow fire, decocting secondary filtering residue, mixing is condensed into the herb liquid 1080 milliliters of 50%, after packed sealing, enters fridge freshness retaining for subsequent use.

A kind of decoction medicine for the treatment of Behcet's syndrome and preparation method thereof, is characterized in that, described instructions of taking is: divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.To take medicine 26-30 agent, all diseases all except and heal.

Medicine provided by the present invention is oral traditional Chinese medicine composition, and it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:

Radix Glycyrrhizae, nature and flavor: sweet, flat, there is effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, be used for the treatment of weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong;

Rhizoma Coptidis, nature and flavor: bitter, cold, there is effect of clearing away heat-fire, dampness, removing toxic substances, be used for the treatment of calentura heresy and enter the telling nosebleed, the damp and hot feeling of stuffiness in chest, have loose bowels of the high heat of heart channel, irritated, delirium or the absurd row of intenseness of heat forcing blood, the vexed insomnia of dysentery, hyperactivity of heart-fire, gastropyretic vomiting or rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain and pathopyretic ulcer, furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, Ting ear, swelling of the vulva, hemorrhoidal bleeding, eczema, scald;

Radix Scutellariae, nature and flavor: bitter, cold, have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect, be used for the treatment of hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tell nosebleed, carbuncle sore tumefacting virus, frequent fetal movement;

Rhizoma Zingiberis, nature and flavor: pungent, hot, have warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, effect of dampness expectorant, be used for the treatment of coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, phlegm retention are breathed with cough;

Fructus Jujubae, nature and flavor: sweet, warm, have effect of invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, and be used for the treatment of insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria, traumatic hemorrhage is controlled in external;

Rhizoma Pinelliae Preparata, nature and flavor: pungent, warm, have effect of drying dampness to eliminate phlegm, are used for the treatment of abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache.

When taking, divided by fried good herb liquid and take for two days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.To take medicine 26-30 agent, all diseases all except and heal.This medicine is that have compatibility science, the efficacy of a drug is powerful, hit pathogenesis, has fully demonstrated dispersing the stagnated pathogen with pungent drugs and lowering the adverse QI with bitter drugs, the Therapeutic Principle that Qinghua is damp and hot with common Chinese herbal medicine for raw material.

Detailed description of the invention

Below embodiments of the present invention are described in detail

Behcet syndrome is also known as Behcet disease, it is a kind of general immune system disease, belong to vasculitic one, it can encroach on the multiple organ of human body, comprise oral cavity, skin, articular muscle, eyes, blood vessel, heart, lung and nervous system etc., main manifestations is repeatedly oral cavity and perineal position ulcer, erythra, lower limb erythema nodosa, eye iritis, esophageal ulcer, small intestinal or colonic ulcer and arthralgia etc., behcet syndrome needs the Drug therapy of rule, comprise the medicine of various immunity moderation, do not treat then prognosis bad, severe patient threat to life.

The traditional Chinese medical science is thought: the disease of cari oris mucosa is many because of internal injury caused by excess of seven emotions, ferritic is weak, the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, cause hot and suffocating, hyperactivity of deficient fire is stifling and send out, as " conscience has heat, normal trouble aphtha " (" medical secrets of official "), " aphtha person, conscience has heat, gas rushes to Jiao, a smoked dispute, pretend skin ulcer also ", " stomach-QI being weak, essence derived from food is few, empty sun is above sent out and is aphtha " (" Shengji Zonglu "), the Ming Dynasty expands imperial physician Xue controlling court and in its " ability to speak class is wanted ", mentions " aphtha part of the body cavity above the diaphragm housing the heart and lungs excess-heat, deficiency-cold in middle-JIAO, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels YIN-fire, individual caused by the change of disease, when controlling it respectively ", the vital organs of the human body of the diseases of oral mucosa such as visible oral ulcer and people have substantial connection.

The present invention is exactly treatment for above-mentioned Behcet's syndrome and a kind of Chinese herbal medicine formula proposed, and adopt herb liquid prepared by this formula, good drug efficacy, curative effect is short, instant effect, and toxic and side effects is little, effectively can treat Behcet's syndrome.Below specific embodiment provided by the present invention is described in detail.

Embodiment 1:

Choose the clean one-level Radix Glycyrrhizae of high-quality 9 grams, Rhizoma Coptidis 4.5 grams, Radix Scutellariae 9 grams, Rhizoma Zingiberis 4.5 grams, 5, Fructus Jujubae, Rhizoma Pinelliae Preparata 6 grams, be ground into graininess respectively stand-by; By the granular medicament splendid attire that crushes after tying in cloth bag, soak half an hour in cold boiled water about, with osmotic drug degree of being organized as, then more soaked medicine is put in boiling machine, added the cold boiled water of medicine 33mm, fried 35 minutes of first intense fire, rear slow fire, decocting secondary filtering residue, mixing is condensed into the herb liquid 1080 milliliters of 50%, after packed sealing, enters fridge freshness retaining for subsequent use.When taking, divided by fried good herb liquid and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.To take medicine 26-30 agent, all diseases all except and heal.

Embodiment 2:

Choose the clean one-level Radix Glycyrrhizae of high-quality 10 grams, Rhizoma Coptidis 5 grams, Radix Scutellariae 10 grams, Rhizoma Zingiberis 5 grams, 6, Fructus Jujubae, Rhizoma Pinelliae Preparata 6.5 grams, be ground into graininess respectively stand-by; By the granular medicament splendid attire that crushes after tying in cloth bag, soak half an hour in cold boiled water about, with osmotic drug degree of being organized as, then more soaked medicine is put in boiling machine, added the cold boiled water of medicine 33mm, fried 35 minutes of first intense fire, rear slow fire, decocting secondary filtering residue, mixing is condensed into the herb liquid 1080 milliliters of 50%, after packed sealing, enters fridge freshness retaining for subsequent use.When taking, divided by fried good herb liquid and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.To take medicine 26-27 agent, all diseases all except and heal.

Embodiment 3:

Choose the clean one-level Radix Glycyrrhizae of high-quality 9 grams, Rhizoma Coptidis 4.5 grams, Radix Scutellariae 9 grams, Rhizoma Zingiberis 4.5 grams, 5, Fructus Jujubae, Rhizoma Pinelliae Preparata 6 grams, be ground into graininess respectively stand-by; By the granular medicament splendid attire that crushes after tying in cloth bag, soak half an hour in cold boiled water about, with osmotic drug degree of being organized as, then more soaked medicine is put in boiling machine, added the cold boiled water of medicine 33mm, fried 35 minutes of first intense fire, rear slow fire, decocting secondary filtering residue, mixing is condensed into the herb liquid 1080 milliliters of 50%, after packed sealing, enters fridge freshness retaining for subsequent use.When taking, divided by fried good herb liquid and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.To take medicine 26-29 agent, all diseases all except and heal.

The present invention picks up the treatment of routine patient through logarithm, Be very effective, and toxic and side effects is little, and part allusion quotation shape case is as follows.

1, patient: Guo XX, man, 21 years old, address: Chengdu, Sichuan Province

Illness symptom: examine May 21 nineteen ninety-five.There is red tuberosity at two medial legs in patient, pain and swelling before three weeks, gradually sees that tuberosity increases, and with fear of cold, fever, hip joint, knee joint and ankle joint pain, stomach is received not fragrant, does not yearningly think drink, once at certain hospital admission, be diagnosed as erythema nodosum, do not imitate through medication treatment.Check that there is the 1-3 centimetre of tuberosity more than 10 that differs in size visible two medial legs and two thigh lower ends, tuberosity slightly exceeds skin surface, in aubergine, by color do not move back, have tenderness, ankle shows edema, once in order to heat clearing away, dredging collateral, the method for invigorating blood circulation after first visit, offers medicine 4 doses.In time examining again May 25, question closely medical history, learnt oral erosion and pudendal ulcer disease, recurrent exerbation 1 year.Inspection is shown in that pharynx is not red, and tonsil is little, neck, lower jaw and inguinal lymph nodes, also not enlargement, cardiopulmonary are normal, and liver spleen does not touch, upper and lower gingival mucosa flushing, visible point-like and small pieces are rotten to the corn, to have shallow in ulcer, the ulcer that visible four Semen Glyciness of labium majus are large and Semen Pisi sativi size is darker, edge is not whole, and without obvious blush, the visible downright bad tunica albuginea in surface is topped, find that there is Gram-positive coccus as smear tests, find no bacillus and exist.Its pulse condition stringy and rapid pulse, red tongue, yellow and greasy fur.This sick motherland medical science surely belongs to hu huo syndrome.Western medicine diagnose is Behcet's syndrome.

Treatment: throw top " herb liquid " and control it, further consultation after patient consumes 8 doses, gums erosion subtracts, and ulcer reduces, labium majus portion ulcer reduces more obvious, and red tuberosity there is no change.And fear of cold, fever symptoms have gone, still feel xerostomia and think drink, stool does not then do, carpal joint pain, advises it to enter according to top again, and oral ulcer external BINGPENG SAN (commercially available) simultaneously, pudendal ulcer external ice clam loose (Pulvis concha Mactrae 18g, Borneolum Syntheticum 3g porphyrize powder external altogether).After entering 6 doses of decoction again, visible both legs tuberosity trend disappears, and still have tenderness, skin is dim brown, and edema is shown in and disappears, and oral erosion and pudendal ulcer all must heal, and only a pimple appears in left cheek.Poor appetite, two is just normal, and pulse condition stringy and thready pulse, body of the tongue is normal.Change the Rhizoma Zingiberis in top into Rhizoma Zingiberis Recens 6g, advise it to continue to take, after entering again 9 doses, see that two shank tuberosity major parts disappear, two calf of the leg respectively stay 1.5 centimetres of large lesser tubercle, dim redness, slightly tenderness, have sour swollen sense during walking, oral cavity and pudendum have no generation ulcer, receive food amelioration, slightly nauseating when taking medicine, tongue arteries and veins is as front, it is advised to enter medicine 6 doses again, with its consolidate curative effect, in time examining July 2, look into it and substantially cure.Visit 1 year, non-goodbye recurrence.

2, patient: Ning XX, female, 25 years old, address: Jianyang City of Sichuan Province

Illness symptom: first visit was on October 15th, 1998.There is red tuberosity at two medial legs in patient, pain and swelling before two weeks, and tuberosity increases gradually, and with fear of cold, fever, hip joint, knee joint and ankle joint pain, stomach is received not fragrant, does not yearningly think drink, Zeng city hospital admission, is diagnosed as: erythema nodosum, through failing to respond to any medical treatment.Check that visible two medial legs and two thigh lower ends have the 1-3.5 centimetre of tuberosity that differs in size several, tuberosity slightly exceeds skin surface, in aubergine, by color do not move back, have tenderness, ankle shows edema, once in order to heat clearing away, dredging collateral, the method for invigorating blood circulation after first visit, offers medicine 3 doses.In time examining October 20, question closely medical history, learnt oral erosion and pudendal ulcer disease, recurrent exerbation is a year and a half again.Inspection is shown in that pharynx is not red, and tonsil is little, neck, lower jaw and inguinal lymph nodes, also not enlargement, cardiopulmonary are normal, and liver spleen does not touch, upper and lower gingival mucosa flushing, visible point-like and small pieces are rotten to the corn, to have shallow in ulcer, the ulcer that the visible several Semen Glycines size of labium majus is darker, edge is not whole, and without blush, the visible downright bad tunica albuginea in surface is topped, find that there is Gram-positive coccus as smear tests, find no bacillus and exist.Its pulse condition stringy and rapid pulse, red tongue, yellow and greasy fur.

Treatment: throw top " herb liquid " and control it, further consultation after patient consumes 7 doses, gums erosion subtracts, and ulcer reduces, labium majus portion ulcer reduces more obvious, and red tuberosity there is no change.And fear of cold, fever symptoms have gone, still feel xerostomia and think drink, stool does not then do, carpal joint pain, advises it to enter according to top again, and oral ulcer external BINGPENG SAN simultaneously, pudendal ulcer external ice clam loose (Pulvis concha Mactrae 20g, Borneolum Syntheticum 3.5g porphyrize powder external altogether).After entering 7 doses of decoction again, visible both legs tuberosity trend disappears, and still have tenderness, skin is dim brown, and edema is shown in and disappears, and oral erosion and pudendal ulcer all must heal, and only a pimple appears in left cheek.Poor appetite, two is just normal, and pulse condition stringy and thready pulse, body of the tongue is normal.Change the Rhizoma Zingiberis in top into Rhizoma Zingiberis Recens 5g, advise it to continue to take, after entering again 9 doses, see that two shank tuberosity major parts disappear, two calf of the leg respectively stay 1.4 centimetres of large lesser tubercle, dim redness, slightly tenderness, have sour swollen sense during walking, oral cavity and pudendum have no generation ulcer, receive food amelioration, slightly nauseating when taking medicine, tongue arteries and veins is as front, it is advised to enter medicine 5 doses again, with its consolidate curative effect, in time examining November 21, all diseases are all removed and heal.Visit 3 year, have no recurrence.

Claims (3)

1. treat a decoction medicine for Behcet's syndrome, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Glycyrrhizae 1-3 part;

Rhizoma Coptidis 1-3 part;

Radix Scutellariae 1-3 part;

Rhizoma Zingiberis 1-3 part;

Fructus Jujubae 1-3 part;

Rhizoma Pinelliae Preparata 1-3 part.

2. the decoction medicine for the treatment of Behcet's syndrome according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Glycyrrhizae 1 part;

Rhizoma Coptidis 1 part;

Radix Scutellariae 1 part;

Rhizoma Zingiberis 1 part;

1 part, Fructus Jujubae;

Rhizoma Pinelliae Preparata 1 part.

3. decoction medicine of the treatment Behcet's syndrome described in a claim 1 or 2 and preparation method thereof, is characterized in that, described method comprises the steps:

A, according to mass parts than choosing the clean one-level Radix Glycyrrhizae of high-quality, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Zingiberis, Fructus Jujubae, Rhizoma Pinelliae Preparata, be ground into graininess respectively stand-by;

B, by the granular medicament splendid attire that crushes after tying in cloth bag, soak half an hour in cold boiled water about, with osmotic drug degree of being organized as, then more soaked medicine is put in boiling machine, added the cold boiled water of medicine 33mm, fried 35 minutes of first intense fire, rear slow fire, decocting secondary filtering residue, mixing is condensed into the herb liquid 1080 milliliters of 50%, after packed sealing, enters fridge freshness retaining for subsequent use.