CN104815297A

CN104815297A - External patch for treating women dysmenorrhea and preparation method of external patch

Info

Publication number: CN104815297A
Application number: CN201510281661.0A
Authority: CN
Inventors: 姚雳
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-05-28
Filing date: 2015-05-28
Publication date: 2015-08-05

Abstract

The invention discloses a preparation method of an external patch for treating women dysmenorrhea. The method comprises the following steps: a, crushing manyflower supplejack stem and leaf, stephania brachyandra diels, grapsidae, trogopterus dung, hyoscyamus niger, nduoh nyaatv buerng, radix curcuma and artemisia anomala into 50-mesh powder according to parts by weight, mixing, adding 75% ethanol according to the material-liquid ratio of 1: 9, reflux extracting for three times and two hours each time, mixing return liquids, and concentrating into extractum of which the relative density is 1.28-1.32 (35 DEG C); b preparing medical stone in parts by weight into 30-mesh powder; c heating wool fat in parts by weight to 40-45 DEG C, adding vaseline in parts by weight, mixing with the extractum obtained in the step a evenly; finally adding the powder obtained in the step b, mixing evenly, and cooling; and putting 4.2g of powder into an inner ring of a nonwoven patch, and applying to a navel twice a day and 5-6 hours each time.

Description

External use plaster being used for the treatment of menalgia and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to a kind of external use plaster being used for the treatment of menalgia and preparation method thereof.

Background technology

The traditional Chinese medical science is thought, on the occasion of menstrual period or front and back of passing through, women occurs that periodically lower abdomen pain or pain draw waist sacrum, very then severe pain faintness person, is called " dysmenorrhea ", also known as " abdominal pain during menstruation ".Namely primary dysmenorrhea starts after mostly being maiden's menophania to occur, or relevant with physical factors, or catches cold because drink in menstrual period is cold, and in cold objective born of the same parents, gas loses Wen Yun, stays, cause vessels of the uterus and be obstructed in blood stasis, obstructed and pain.Secondary dysmenorrhea mostly is Women of Childbearing Age and catches cold menstrual period, or puerperal is careless, when wind catches cold, cold-damp visitor is in born of the same parents, or have repeatedly artificial abortion's history, impairment of the uterine collateral, the stagnant uterus of the blood circulating out of vessels stasis of blood, vessels of the uterus, stagnation of blood stasis, functional activity of QI being not smooth, the body fluid interruption of service, poly-and life is wet and is made expectorant, wet, expectorant, the stasis of blood be the disease of Cheng mass in the abdomen with the passing of time, thus cold be primary disease main pathogenesis with the stasis of blood.

Dysmenorrhea is common symptom in women, and after pre-marital dysmenorrhea is particularly given birth to after growing up after marriage, dysmenorrhea can disappear naturally, can treat.Except individual cases.But the pain time of dysmenorrhea reaches 3 days persons should be treated.The treatment of primary dysmenorrhea, mainly symptomatic treatment, with pain relieving, calmness is main, all adopts Comprehensive Treatment to comprise spirit in recent years and dredges, Chinese medicine, Western medicine and acupuncture and moxibustion therapy.General treatment: pay attention to psychotherapy, eliminates nervous and misgivings.Enough rests and sleep, the exercise of rule and appropriateness, smoking cessation.Drug therapy is aided with when pain is impatient at.Drug therapy: the medicine that oral PGSI is conventional has ibuprofen, ketoprofen, meclofenamic acid, diclofenac etc.Oral contraceptive is applicable to the dysmenorrhea women requiring contraception, and effective percentage reaches more than 90%.

Summary of the invention

The object of this invention is to provide a kind of external use plaster being used for the treatment of menalgia and preparation method thereof.

The external use plaster being used for the treatment of menalgia of the present invention, is made up of the raw material of following parts by weight: Ramulus et folium berchemiae floribundae 12 ~ 15 parts, Stephania brachyandra 24 ~ 26 parts, square Eriocheir sinensis 18 ~ 20 parts, Oletum Trogopterori 20 ~ 23 parts, Semen Hyoscyami 23 ~ 25 parts, Spica piperis betlis 28 ~ 30 parts, 13 ~ 15 parts, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 22 ~ 25 parts, lanoline 5 ~ 7 parts, Maifanitum 4 ~ 5 parts, vaseline 22 ~ 25 parts.

As optimization, this is used for the treatment of the external use plaster of menalgia, is made up of the raw material of following parts by weight: Ramulus et folium berchemiae floribundae 13 parts, Stephania brachyandra 25 parts, square Eriocheir sinensis 19 parts, Oletum Trogopterori 21 parts, Semen Hyoscyami 24 parts, Spica piperis betlis 29 parts, 14 parts, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 23 parts, lanoline 6 parts, Maifanitum 4.5 parts, vaseline 24 parts.

This is used for the treatment of the preparation method of the external use plaster of menalgia, comprises the following steps:

A, the Ramulus et folium berchemiae floribundae of described parts by weight, Stephania brachyandra, square Eriocheir sinensis, Oletum Trogopterori, Semen Hyoscyami, Spica piperis betlis, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae are ground into 50 object powder mixing after, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (35 DEG C);

B, the Maifanitum of described parts by weight is made 300 object powder;

C, the lanoline of described parts by weight is heated to 40 ~ 45 DEG C, then adds extractum in the vaseline of described parts by weight and step a and stir; Cool after finally adding the powder mix homogeneously in step b.Then medicine taking amount 4.2 grams is inserted in the internal ring of non-woven fabrics subsides, sticks on umbilicus, every day 2 times, each 5 ~ 6 hours.

The present invention is used for the treatment of in the component of the external use plaster of menalgia, Ramulus et folium berchemiae floribundae expelling wind and removing dampness; Promoting blood circulation and stopping pain; Main air pain of dampness syndrome; Stomachache; Dysmenorrhea; Puerperal abdonimal pain; Traumatic injury; Tuberculosis of bone and joint; Osteomyelitis; Infantile malnutrition; Hepatitis; Liver cirrhosis.Stephania brachyandra promoting flow of QI and blood; Wind-expelling pain-stopping; Heat-clearing and toxic substances removing; Main stomachache; Rheumatic arthralgia; Traumatic injury; Dysmenorrhea; Carbuncle furuncle and phyma poison; Eczema.Side's Eriocheir sinensis removing blood stasis, dysmenorrhea; Cure mainly induced abortion, chronic nephritis, puerperal, blood closed, women's amenorrhea; Still can control nervous toothache, acute toothache, sprain, lumbago, uterine prolapse etc.Oletum Trogopterori promoting blood circulation to remove blood stasis, parch to black stops blooding; Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.Spica piperis betlis warming spleen and stomach for dispelling cold, activating collaterals to relieve pain, removing toxic substances and promoting subsidence of swelling; For flu, cough with asthma, traumatic injury, rheumatic ostalgia, stomachache, abdominal distention and pain, menoxenia, dysmenorrhea, puerperal abdonimal pain, toothache, venom, traumatic hemorrhage, burn and scald, mastitis etc.Semen Hyoscyami relieving spasm to stop pain, relievings asthma, and calms the nerves; Cure mainly for gastral cavilty spasm and pain, breath with cough, demented.The circulation of qi promoting of Rhizoma Curcumae Longae removing blood stasis, inducing menstruation to relieve menalgia; Twinge for the breast side of body, amenorrhea ， WEIJIA, rheumatism shoulder arm pain, tumbling and swelling.Herba Artemisiae Anomalae dissipating blood stasis to promote menstruationg; Hemostasia and detumescence; Promoting digestion and removing stagnation; Main warp closes; Dysmenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lochiorrhea, lump in the abdomen; Traumatic injury; Incised wound is hemorrhage; Rheumatic arthralgia; Have blood in stool; Hematuria; Carbuncle pyogenic infections from tumour or sore; Scald; Abdominal pain due to retention of food; Dysentery.

The present invention is used for the treatment of the external use plaster of menalgia, each component compatibility, uses, given full play to drug effect as plaster; There is effect of blood circulation promoting and blood stasis dispelling, warming spleen and stomach for dispelling cold, dissipating blood stasis to promote menstruationg, relieving spasm to stop pain; Be used for the treatment of dysmenorrhea and there is good curative effect.

Detailed description of the invention

The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.

Embodiment 1:a, Ramulus et folium berchemiae floribundae 13 grams, Stephania brachyandra 25 grams, square Eriocheir sinensis 19 grams, Oletum Trogopterori 21 grams, Semen Hyoscyami 24 grams, Spica piperis betlis 29 grams, 14 grams, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 23 grams are ground into 50 object powder mixing after, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (35 DEG C);

B, Maifanitum 4.5 is restrained into 300 object powder;

C, lanoline 6 grams is heated to 40 ~ 45 DEG C, then adds extractum in vaseline 24 grams and step a and stir; Cool after finally adding the powder mix homogeneously in step b.

Embodiment 2:a, Ramulus et folium berchemiae floribundae 12 grams, Stephania brachyandra 24 grams, square Eriocheir sinensis 18 grams, Oletum Trogopterori 20 grams, Semen Hyoscyami 23 grams, Spica piperis betlis 28 grams, 13 grams, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 22 grams are ground into 50 object powder mixing after, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (35 DEG C);

B, Maifanitum 4 is restrained into 300 object powder;

C, lanoline 5 grams is heated to 40 ~ 45 DEG C, then adds extractum in vaseline 22 grams and step a and stir; Cool after finally adding the powder mix homogeneously in step b.

Embodiment 3:a, Ramulus et folium berchemiae floribundae 15 grams, Stephania brachyandra 26 grams, square Eriocheir sinensis 20 grams, Oletum Trogopterori 23 grams, Semen Hyoscyami 25 grams, Spica piperis betlis 30 grams, 15 grams, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 25 grams are ground into 50 object powder respectively, then mix homogeneously, by solid-liquid ratio 1:9, add 75% ethanol, reflux, extract, 3 times, each 2 hours, merge backflow; Be condensed into the extractum that relative density is 1.28 ~ 1.32 (35 DEG C);

B, Maifanitum 5 is restrained into 300 object powder;

C, lanoline 7 grams is heated to 40 ~ 45 DEG C, then adds extractum in vaseline 25 grams and step a and stir; Cool after finally adding the powder mix homogeneously in step b.

Pertinent clinical data is as follows: physical data: in 318 routine cases, oldest 45 years old, minimum 17 years old, is divided into three groups at random, divides and often organizes 106 examples.Three groups of cases through statistical analysis no significant difference, have comparability in age etc.All cases are all made a definite diagnosis with reference to the diagnosis basis in " Chinese medical disease Standardization of diagnosis and curative effect " and efficacy assessment standard.

Diagnosis basis: menstrual period or lower abdomen pain before and after row, pain and waist sacrum, very then faint.In periodical attack.Be apt to occur in young maiden.Get rid of the caused stomachache of pelvic cavity organic disease.

Therapeutic Method: the external use plaster treatment that three groups of cases accept embodiment 1 respectively, embodiment 2, embodiment 3 are used for the treatment of menalgia, sticks on umbilicus position, every day 2 times, each 5 ~ 6 hours, six days courses for the treatment of.

Efficacy evaluation: cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.Take a turn for the better: pain relief or pain disappear, but can not maintain more than 3 months.Do not heal: pain has no improvement.After three courses for the treatment of, three groups of case efficacy results are in table 1:

Claims

1. be used for the treatment of the external use plaster of menalgia, its feature is made at the raw material by following weight powder number: Ramulus et folium berchemiae floribundae 12 ~ 15 parts, Stephania brachyandra 24 ~ 26 parts, square Eriocheir sinensis 18 ~ 20 parts, Oletum Trogopterori 20 ~ 23 parts, Semen Hyoscyami 23 ~ 25 parts, Spica piperis betlis 28 ~ 30 parts, 13 ~ 15 parts, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 22 ~ 25 parts, lanoline 5 ~ 7 parts, Maifanitum 4 ~ 5 parts, vaseline 22 ~ 25 parts.

2. the external use plaster being used for the treatment of menalgia according to claim 1; It is characterized in that being made up of the raw material of following parts by weight: Ramulus et folium berchemiae floribundae 13 parts, Stephania brachyandra 25 parts, square Eriocheir sinensis 19 parts, Oletum Trogopterori 21 parts, Semen Hyoscyami 24 parts, Spica piperis betlis 29 parts, 14 parts, Rhizoma Curcumae Longae, Herba Artemisiae Anomalae 23 parts, lanoline 6 parts, Maifanitum 4.5 parts, vaseline 24.

3. be used for the treatment of a preparation method for the external use plaster of menalgia described in claim 1, it is characterized in that comprising the following steps:

B, the Maifanitum of described parts by weight is made 300 object powder;

C, the lanoline of described parts by weight is heated to 40 ~ 45 DEG C, then adds extractum in the vaseline of described parts by weight and step a and stir; Cool after finally adding the powder mix homogeneously in step b.