CN104815180A - Traditional Chinese medicine preparation for treating infantile malnutrition and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating infantile malnutrition and preparation method thereof Download PDF

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CN104815180A
CN104815180A CN201510258900.0A CN201510258900A CN104815180A CN 104815180 A CN104815180 A CN 104815180A CN 201510258900 A CN201510258900 A CN 201510258900A CN 104815180 A CN104815180 A CN 104815180A
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herba
chinese medicine
fructus crataegi
infantile malnutrition
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霍玉莲
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating infantile malnutrition and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following main raw material medicines in parts by weight: 10-16 parts of white atractylodes rhizome, 8-15 parts of green orchid, 7-12 parts of anneslea fragrans Wall., 5-13 parts of striga asiatica, 11-15 parts of lily, 6-12 parts of white strawberry, 8-14 parts of erigeron breviscapus, 12-16 parts of jujubes, 7-11 parts of nervilia fordii, 10-13 parts of clove, 8-15 parts of all-grass of longspike uraria, 6-14 parts of psychotria serpens, 9-11 parts of fructus aurantii, 11-16 parts of hawthorns, 4-6 parts of stachys sieboldii, 7-12 parts of erythrina indica leaves and 9-13 parts of radix fici simplicissimae. The traditional Chinese medicine preparation disclosed by the invention is remarkable in curative effect, capable of treating both symptoms and root causes, and free from toxic and side effects, has the effects of tonifying spleen and removing food retention, clearing heart and tranquilizing, nourishing spleen and stomach, tonifying qi and nourishing blood, warming kidney and supporting yang, relaxing tendons and activating collaterals, killing parasites and expelling roundworms, inducing diuresis and alleviating edema, and nourishing yin and tonifying deficiency, can adjust spleen and stomach functions and recover viscera functions, and has definite clinical effects.

Description

Chinese medicine for the treatment of infantile malnutrition and preparation method thereof
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine for the treatment of infantile malnutrition and preparation method thereof.
Background technology
Infantile malnutrition is due to improper feeding, or the impact of other diseases, causes spleen and stomach function impaired, the chronic disease of one that gas-liquid consumption is hindered and formed gradually.Primary disease morbidity is without obviously seasonal, and within less than 5 years old, children's is common.The cause of disease: this is because infant internal organs in period are tender and lovely, and the physiological function of body is not yet ripe perfect, and growth promoter is rapid, large to the requirement of essence of water and grain.Therefore, create physiological " the spleen tending to insufficiency usually ".And a lot of head of a family fears that child does not have enough to eat, just as force-fed duck, feeding diet still can not from the infant of joint.As the saying goes: " being important to suckle on schedule, being important to feed in moderation ", be never eat more just can grow better.Who does not know, feeds food too early, sweet fertilizer, raw and cold food overfeed, can the gas of impairing the spleen and stomach, and wasting QI-blood body fluid, just there will be digestive functional disturbance, produces taste on pathology deficient and the card of infantile malnutrition occurs.Clinical manifestation: emaciated physique, severe one dries up weakness and emaciation, and diet is abnormal, and large dry stool is rare uncomfortable, abdominal distention, lustreless complexion, and hypotrichosis is withered and yellow, and agitation is not peaceful or dispirited, rubs eyebrow brush eye, suckes finger, grind one's teeth in sleep.
Determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs 1. main symptom: (1) infantile malnutrition gas is demonstrate,proved: syndrome body is slightly thin, or body weight does not increase, the few China of shallow complexion, hypotrichosis, appetite stimulator, abdominal distention, impatient irritability, large dry stool is rare uncomfortable, pale tongue, white and thin fur, thready pulse, and fingerprint is light.The rule for the treatment of adjusts spleen to help fortune.(2) infantile malnutrition card: syndrome is obviously become thin, shallow complexion lacks magnificent or pallor is simple and unadorned, and abdominal distention bulge, abdomen has blue veins, indigestion and loss of appetite, and irritable rubs eyebrow, digs nose, lassitude and weak, and large dry stool is rare uncomfortable, pale tongue, and tongue is white thick greasy, thready and rolling pulse, and fingerprint purple is stagnant.Rule for the treatment of removing food stagnancy reason spleen.(3) chronic infantile malnutrition card: syndrome is obviously become thin, skinny as bavin, shallow complexion or pale, and hair is sparse withered and yellow, and abdomen is recessed as boat, lethargy, lazy speech is hypologia, indifferently dull, uneasy sleeping at night, and head is large, and item is thin, anorexia, crying weakly, loose stool or rare clearly, pale tongue, tongue is few, and deep pulse is thin and delicate, and fingerprint is latent not to be shown.Rule for the treatment of invigorating qi and benefiting blood.2. accompanied symptoms: (1) eye infantile consumption: syndrome is double sees nyctalopia, two dryness and uneasy feeling of the eye, photophobia photophobia, corneal opacity, nebula hides eyeball, and canthus is red rotten, ophthalmic pruritus.Rule for the treatment of nourishing blood to suppress the hyperactive liver, YIN nourishing improving eyesight.(2) aphtha card: syndrome is double sees aphtha of the mouth and tongue, rotten to the corn, halitosis is flushing, irritated, and night is sleeping not peaceful, and dysphoria with feverish sensation in the chest palms and soles, cries and screams during feed, oliguria with yellow urine.Rule for the treatment of clearing heart fire, Yin-nourishing and body fluid promoting.(3) infantile malnutrition with edema and abdominal distention card: syndrome is double sees whole body swelling, the puffiness of the eyes, and face swells, and god is tired, and cold extremities, oliguria, pallor is simple and unadorned.Rule for the treatment of spleen invigorating warming YANG, inducing diuresis to remove edema.Other therapies: 1. massage therapy.(1) clear spleen reinforcing warp, rub plate door, push away Sihengwen, rub the middle part of gastric cavity, rub abdomen, rubs Tianshu, rubs tsu san li, chiropractic.Be applicable to infantile malnutrition gas card.(2) push away spleen soil, rub plate door, the abdomen that rubs rubs umbilicus, and chiropractic rubs tsu san li.Be applicable to infantile malnutrition card.(3) spleen reinforcing warp, pushes away SAN GUAN, rubs wailaog, Eight Diagrams in fortune, pinches Sihengwen, divides and pushes away abdominal part, rub abdomen, and the some middle part of gastric cavity, rubs tsu san li, chiropractic.Be applicable to chronic infantile malnutrition card.2. medicine external treatment.(1) Natrii Sulfas, Radix Et Rhizoma Rhei, Gardenia, Semen Armeniacae Amarum, Semen Persicae.Be smalls altogether, add flour appropriate, a little each with Ovum Gallus domesticus album, Bulbus Allii Fistulosi juice, vinegar, Chinese liquor, furnishing pasty state, spreads on umbilical part, and external gauze covers, adhesive tape is fixed.1 time on the 1st, be used in conjunction 3 ~ 5.Demonstrate,prove for infantile malnutrition.(2) Semen Raphani is ground into powder in right amount, is in harmonious proportion, sticks in SHENQUE acupoint with water, and external gauze covers, adhesive tape is fixed.
Application publication number CN 102441144 A(application number 201110396640.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of infantile malnutrition, this Chinese medicine, is made by certain parts by weight for active component with Endothelium Corneum Gigeriae Galli, Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Pupa bombycis, Fructus Toosendan, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, Fructus Hordei Germinatus, Fructus Quisqualis, Radix Angelicae Sinensis, Rhizoma Curcumae, the Radix Aucklandiae, Caulis et Folium fici Tikouae, Folium Granati, Radix Salviae Miltiorrhizae and Radix Curcumae.Application publication number CN 103202958 A(application number 201310067390.X) Chinese patent literature disclose a kind of Chinese medicine for the treatment of infantile malnutrition, the weight proportion of its each raw material components is: Semen Armeniacae Amarum 8-12, Semen Persicae 8-12, Pericarpium Zanthoxyli 8-12, Fructus Gardeniae 28-32, Natrii Sulfas 28-32, Semen Momordicae 18-22, Herba Paederiae 13-17, Folium Crataegi 4-8, Radix Pseudostellariae 6-10, Justicia procumbens linn. 6-10, Laurel 6-10, Herba Cymbopogonis Citrari 4-8, flower of Radix Notoginseng 1-5.Application publication number CN 104056171 A(application number 201410294362.6) Chinese patent literature disclose a kind of Chinese medicine for the treatment of infantile malnutrition, be made up of the crude drug of following weight portion, SHANZHIZI 8-10 part, Fructus Quisqualis 5-8 part, Herba Paederiae 17-20 part, Radix Astragali 10-14 part, Fructus Amomi Rotundus 5-8 part, Fructus Toosendan 10-14 part, Semen Cassiae 6-8 part, Semen Raphani 7-13 part, Folium Perillae 7-10 part, Rhizoma Sparganii 5-8 part, Flos Magnoliae 4-7 part, Herba Dendrobii 4-8 part, Herba Scutellariae Barbatae 2-7 part, Radix Stellariae 18-25 part, Pericarpium Citri Reticulatae 4-5 part, Semen Sinapis Albae 4-5 part.
At present, treatment infantile malnutrition clinically great majority is aid digestion class medicines, and this type of curative effect of medication is undesirable, cures the symptoms, not the disease, and because of children's's function weakness, applies this type of drug side effect large, affect children's upgrowth and development.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine for the treatment of infantile malnutrition and preparation method thereof.The present invention is evident in efficacy, treating both the principal and secondary aspects of a disease, has no side effect, there is spleen invigorating removing food stagnancy, clearing away heart-fire for tranquillization, take a tonic or nourishing food to build up one's health taste, effect that invigorating qi and benefiting blood, warming the kidney to activate YANG, relaxing muscles and tendons and activating QI and blood in the collateral, parasite killing drive ascarid, inducing diuresis to remove edema, yin nourishing tonify deficiency, can adjust spleen and stomach function, recover function, clinical efficacy is definite.
Technical scheme of the present invention is:
The Chinese medicine for the treatment of infantile malnutrition, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Atractylodis Macrocephalae 10-16, Herba mazi japonici 8-15, Cortex Annesleae Fragrantis 7-12, Herba Lobeliae Chinensis 5-13, Bulbus Lilii 11-15, Herba Fragariae nilerrensis 6-12, Herba Erigerontis 8-14, Fructus Jujubae 12-16, Folium Nerviliae fordii 7-11, Flos Caryophylli 10-13, Herba urariae macrostachyae 8-15, Ramulus et Folium Psychotriae Serpentis 6-14, Fructus Aurantii 9-11, Fructus Crataegi 11-16, Rhizoma Humatae Tyermanni 4-6, Folium Erythrinae 7-12, Herba Fici Simplicissimae 9-13.
The Chinese medicine for the treatment of infantile malnutrition, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Atractylodis Macrocephalae 12-15, Herba mazi japonici 10-13, Cortex Annesleae Fragrantis 9-11, Herba Lobeliae Chinensis 7-10, Bulbus Lilii 12-14, Herba Fragariae nilerrensis 8-11, Herba Erigerontis 9-12, Fructus Jujubae 13-15, Folium Nerviliae fordii 8-10, Flos Caryophylli 11-12, Herba urariae macrostachyae 10-12, Ramulus et Folium Psychotriae Serpentis 8-12, Fructus Aurantii 9.5-10.5, Fructus Crataegi 12-14, Rhizoma Humatae Tyermanni 4.5-5.5, Folium Erythrinae 9-11, Herba Fici Simplicissimae 10-12.
The Chinese medicine for the treatment of infantile malnutrition, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: the Rhizoma Atractylodis Macrocephalae 13, Herba mazi japonici 11, Cortex Annesleae Fragrantis 10, Herba Lobeliae Chinensis 9, Bulbus Lilii 13, Herba Fragariae nilerrensis 10, Herba Erigerontis 10, Fructus Jujubae 14, Folium Nerviliae fordii 9, Flos Caryophylli 11.5, Herba urariae macrostachyae 11, Ramulus et Folium Psychotriae Serpentis 10, Fructus Aurantii 10, Fructus Crataegi 13, Rhizoma Humatae Tyermanni 5, Folium Erythrinae 10, Herba Fici Simplicissimae 11.
Present invention also offers the preparation method Chinese medicine of aforementioned therapies infantile malnutrition being made pharmaceutically acceptable syrup, pill and thick paste agent.
The preparation method of described syrup is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10-15g Testa Tritici skin (preferably every 100g Fructus Crataegi adds 13g Testa Tritici skin), Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140-180 DEG C and (preferably put it in the Electric heat oven of 160 DEG C), smoke 10-30 minute (preferably smoking 20 minutes), take out, cool, sieve removes Testa Tritici skin, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6-8 hour (preferably baking 7 hours), take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11-14 times (preferred amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight) of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into 1:1 medicinal liquid;
(4) sucrose and antiseptic are joined in step (3) gained medicinal liquid, are stirred to dissolve, boil, let cool, thin up, make sucrose concentration be 70%(g/mL), concentration of preservatives is 0.2%(g/mL), stir evenly, fill, to obtain final product.
The preparation method of described pill is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10-15g Testa Tritici skin (preferably every 100g Fructus Crataegi adds 13g Testa Tritici skin), Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140-180 DEG C and (preferably put it in the Electric heat oven of 160 DEG C), smoke 10-30 minute (preferably smoking 20 minutes), take out, cool, sieve removes wheat bran, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6-8 hour (preferably baking 7 hours), take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11-14 times (preferred amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight) of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into the clear paste (preferred filtrate is condensed into the clear paste that relative density is 1.22) that relative density is 1.18-1.24, then refined honey is added, every 100kg clear paste adds the preferred every 100kg clear paste of refined honey 160-200kg(and adds refined honey 180kg), make honeyed pill, the weight of every ball is 0.1-0.2 gram (preferably the weight of every ball is 0.15 gram).
The preparation method of described thick paste agent is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10-15g Testa Tritici skin (preferably every 100g Fructus Crataegi adds 13g Testa Tritici skin), Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140-180 DEG C and (preferably put it in the Electric heat oven of 160 DEG C), smoke 10-30 minute (preferably smoking 20 minutes), take out, cool, sieve removes wheat bran, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6-8 hour (preferably baking 7 hours), take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11-14 times (preferred amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight) of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into the thick paste (preferred filtrate is condensed into the thick paste that relative density is 1.32) that relative density is 1.31-1.35, add refined honey, every 100kg thick paste adds the preferred every 100kg thick paste of refined honey 150-180kg(and adds refined honey 170kg), micro-refining, foam removal, seal and get final product in dress aseptic bottle.
The Chinese medicine for the treatment of infantile malnutrition provided by the invention is made up through scientific compatibility of pure natural Chinese herbal medicine.In addition, excellent results of the present invention also shows:
1, evident in efficacy, treating both the principal and secondary aspects of a disease;
, have no side effect 2, safely;
3, there is spleen invigorating removing food stagnancy, clearing away heart-fire for tranquillization, take a tonic or nourishing food to build up one's health taste, effect that invigorating qi and benefiting blood, warming the kidney to activate YANG, relaxing muscles and tendons and activating QI and blood in the collateral, parasite killing drive ascarid, inducing diuresis to remove edema, yin nourishing tonify deficiency, can adjust spleen and stomach function, recover function, clinical efficacy is definite;
4, preparation method is simple;
5, raw material is cheap and easy to get.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the Chinese medicine for the treatment of infantile malnutrition, the primary raw material medicine getting following weight parts is prepared from (every part is 500g): the Rhizoma Atractylodis Macrocephalae 10 parts, Herba mazi japonici 8 parts, Cortex Annesleae Fragrantis 7 parts, Herba Lobeliae Chinensis 5 parts, Bulbus Lilii 11 parts, Herba Fragariae nilerrensis 6 parts, Herba Erigerontis 8 parts, 12 parts, Fructus Jujubae, Folium Nerviliae fordii 7 parts, Flos Caryophylli 10 parts, Herba urariae macrostachyae 8 parts, Ramulus et Folium Psychotriae Serpentis 6 parts, Fructus Aurantii 9 parts, Fructus Crataegi 11 parts, Rhizoma Humatae Tyermanni 4 parts, Folium Erythrinae 7 parts, Herba Fici Simplicissimae 9 parts.
The preparation method of the Chinese medicine syrup of above-mentioned treatment infantile malnutrition is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10g Testa Tritici skin, and Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140 DEG C, smoke 10 minutes, take out, cool, sieve removes Testa Tritici skin, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6 hours, take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11 times of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into 1:1 medicinal liquid;
(4) sucrose and sodium benzoate are joined in step (3) gained medicinal liquid, are stirred to dissolve, boil, let cool, thin up, make sucrose concentration be 70%(g/mL), concentration of preservatives is 0.2%(g/mL), stir evenly, fill, to obtain final product.
The using method of the Chinese medicine syrup of gained of the present invention treatment infantile malnutrition: oral, one-year-old with 5 milliliters next time, 1 ~ 2 years old one time 8 milliliters, 3 ~ 5 years old one time 10 milliliters, 5 years old with last 15 milliliters, 3 times on the one.
embodiment 2the Chinese medicine for the treatment of infantile malnutrition, the primary raw material medicine getting following weight parts is prepared from (every part is 500g): the Rhizoma Atractylodis Macrocephalae 16 parts, Herba mazi japonici 15 parts, Cortex Annesleae Fragrantis 12 parts, Herba Lobeliae Chinensis 13 parts, Bulbus Lilii 15 parts, Herba Fragariae nilerrensis 12 parts, Herba Erigerontis 14 parts, 16 parts, Fructus Jujubae, Folium Nerviliae fordii 11 parts, Flos Caryophylli 13 parts, Herba urariae macrostachyae 15 parts, Ramulus et Folium Psychotriae Serpentis 14 parts, Fructus Aurantii 11 parts, Fructus Crataegi 16 parts, Rhizoma Humatae Tyermanni 6 parts, Folium Erythrinae 12 parts, Herba Fici Simplicissimae 13 parts.
The preparation method of the Chinese medicine syrup of above-mentioned treatment infantile malnutrition is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 15g Testa Tritici skin, and Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 180 DEG C, smoke 30 minutes, take out, cool, sieve removes Testa Tritici skin, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 8 hours, take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 14 times of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into 1:1 medicinal liquid;
(4) sucrose and potassium sorbate are joined in step (3) gained medicinal liquid, are stirred to dissolve, boil, let cool, thin up, make sucrose concentration be 70%(g/mL), concentration of preservatives is 0.2%(g/mL), stir evenly, fill, to obtain final product.
model case one:week XX, female, 4 years old.Near over the past half year, becoming thin appears in infant, anorexia, hot-tempered, particular about food.Once Chinese and western medicine medicine was taken, without taking a turn for the better.Within 2007, JIUYUE is examined on the 13rd.Examine and see infant emaciated physique, lusterless complexion, indigestion and loss of appetite, hot-tempered, light red tongue, tongue are yellowish and greasy, soft and thready pulse and sliding.Be diagnosed as infantile malnutrition.Take the present embodiment gained treatment infantile malnutrition Chinese medicine syrup, oral, one time 10 milliliters, 3 times on the one.After taking two weeks, appetite is obviously improved.Continue to take 1 month, all diseases disappear, and body weight increases, complexion amelioration.Follow up a case by regular visits to and do not recur again.
embodiment 3the Chinese medicine for the treatment of infantile malnutrition, the primary raw material medicine getting following weight parts is prepared from (every part is 500g): the Rhizoma Atractylodis Macrocephalae 12 parts, Herba mazi japonici 10 parts, Cortex Annesleae Fragrantis 9 parts, Herba Lobeliae Chinensis 7 parts, Bulbus Lilii 12 parts, Herba Fragariae nilerrensis 8 parts, Herba Erigerontis 9 parts, 13 parts, Fructus Jujubae, Folium Nerviliae fordii 8 parts, Flos Caryophylli 11 parts, Herba urariae macrostachyae 10 parts, Ramulus et Folium Psychotriae Serpentis 8 parts, Fructus Aurantii 9.5 parts, Fructus Crataegi 12 parts, Rhizoma Humatae Tyermanni 4.5 parts, Folium Erythrinae 9 parts, Herba Fici Simplicissimae 10 parts.
The preparation method of the Chinese medicine pill of above-mentioned treatment infantile malnutrition is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 13g Testa Tritici skin, and Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 160 DEG C, smoke 20 minutes, take out, cool, sieve removes wheat bran, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 7 hours, take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into the clear paste that relative density is 1.22, then refined honey is added, every 100kg clear paste adds refined honey 180kg, makes honeyed pill, and the weight of every ball is 0.15 gram.
model case two:king XX, female, 3 years old.Over nearly 1 year, there is the symptoms such as yellowish complexion is become thin, inappetence in infant.Once multi-medicament treatment was taken, invalid.On April 20th, 2009 examines.Examine and see infant emaciated physique, shallow complexion, inappetence, lethargy, hypotrichosis is withered and yellow, irritable, pale tongue, white and thin fur.Be diagnosed as infantile malnutrition.Take the Chinese medicine pill of the present embodiment gained treatment infantile malnutrition, each 6 balls, every day 3 times, the head of a family rubs pill broken, becomes soup to feed to infant by warm water molten in little spoon.After taking 20 days, infant spirit amelioration, appetite increases.Continue to take 1 month, its body constitution turns for the better by and large, and face is ruddy, prothymia, and diet is normal, and body weight is close to normal health children's body weight.Follow up a case by regular visits to and do not recur again.
embodiment 4the Chinese medicine for the treatment of infantile malnutrition, the primary raw material medicine getting following weight parts is prepared from (every part is 500g): the Rhizoma Atractylodis Macrocephalae 15 parts, Herba mazi japonici 13 parts, Cortex Annesleae Fragrantis 11 parts, Herba Lobeliae Chinensis 10 parts, Bulbus Lilii 14 parts, Herba Fragariae nilerrensis 11 parts, Herba Erigerontis 12 parts, 15 parts, Fructus Jujubae, Folium Nerviliae fordii 10 parts, Flos Caryophylli 12 parts, Herba urariae macrostachyae 12 parts, Ramulus et Folium Psychotriae Serpentis 12 parts, Fructus Aurantii 10.5 parts, Fructus Crataegi 14 parts, Rhizoma Humatae Tyermanni 5.5 parts, Folium Erythrinae 11 parts, Herba Fici Simplicissimae 12 parts.
The preparation method of the Chinese medicine thick paste agent of above-mentioned treatment infantile malnutrition is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 13g Testa Tritici skin, and Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 160 DEG C, smoke 20 minutes, take out, cool, sieve removes wheat bran, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 7 hours, take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filters, filtrate is condensed into the thick paste that relative density is 1.32, add refined honey, every 100kg thick paste adds refined honey 170kg, micro-refining, foam removal, seals and get final product in dress aseptic bottle.
model case three:high XX, man, 5 years old.Over the past two years, there is the symptom such as yellowish complexion, dried and withered hairs of becoming thin in infant.Once Drug therapy was carried out without improvement at local hospital.On November 16th, 2009 examines.Examine and see infant shallow complexion, emaciated physique, the withered knot of hair, listlessness, crying weakly, fingerprint color is light, and pale tongue, tongue are yellowish.Be diagnosed as infantile malnutrition.Take the Chinese medicine thick paste agent of the present embodiment gained treatment infantile malnutrition, each 10g, 3 times on the one, drink-service washed open by boiled water.Take three weeks, the infant state of an illness is eased, and spirit takes a turn for the better.Continue to take 1 month, all diseases disappear, and laboratory checking index recovers normal.Follow up a case by regular visits to and do not recur again.
embodiment 5the Chinese medicine for the treatment of infantile malnutrition, the primary raw material medicine getting following weight parts is prepared from (every part is 500g): the Rhizoma Atractylodis Macrocephalae 13 parts, Herba mazi japonici 11 parts, Cortex Annesleae Fragrantis 10 parts, Herba Lobeliae Chinensis 9 parts, Bulbus Lilii 13 parts, Herba Fragariae nilerrensis 10 parts, Herba Erigerontis 10 parts, 14 parts, Fructus Jujubae, Folium Nerviliae fordii 9 parts, Flos Caryophylli 11.5 parts, Herba urariae macrostachyae 11 parts, Ramulus et Folium Psychotriae Serpentis 10 parts, Fructus Aurantii 10 parts, Fructus Crataegi 13 parts, Rhizoma Humatae Tyermanni 5 parts, Folium Erythrinae 10 parts, Herba Fici Simplicissimae 11 parts.
The preparation method of the Chinese medicine syrup of above-mentioned treatment infantile malnutrition is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 13g Testa Tritici skin, and Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 160 DEG C, smoke 20 minutes, take out, cool, sieve removes Testa Tritici skin, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 7 hours, take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into 1:1 medicinal liquid;
(4) sucrose and potassium sorbate are joined in step (3) gained medicinal liquid, are stirred to dissolve, boil, let cool, thin up, make sucrose concentration be 70%(g/mL), concentration of preservatives is 0.2%(g/mL), stir evenly, fill, to obtain final product.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Rhizoma Atractylodis Macrocephalae: base is former: be the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.The property of medicine: bitter, sweet, temperature.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Herba mazi japonici: base is former: be the herb of goatweed Mazus japonicus.The property of medicine: bitter in the mouth; Micro-sweet; Cool in nature.Function cures mainly: heat-clearing and toxic substances removing, and dampness removing is treating stranguria, spleen invigorating removing food stagnancy.Main pyretic toxicity carbuncle, impetigo, furuncle, burn and scald, urinary tract infection, ascites, icterohepatitis, aquation is bad, infantile malnutrition.
Cortex Annesleae Fragrantis: base is former: be bark or the leaf of plant of theaceae tea pears.The property of medicine: puckery; Micro-hardship; Cool.Return liver, stomach, large intestine channel.Function cures mainly: promoting the circulation of QI to relieve pain; Help digestion antidiarrheal.Main heart peratodynia, dyspepsia, dysentery, hepatitis.
Herba Lobeliae Chinensis: base is former: be the herb of Scrophulariaceae Herba Lobeliae Chinensis platymiscium Herba Lobeliae Chinensis.The property of medicine: sweet, light, cool.Function cures mainly: heat clearing away, removing food stagnancy.For infantile malnutrition, Infantile Summer Fever, infantile diarrhea, icterohepatitis.
Bulbus Lilii: base is former: be the dry meat scale leaf of liliaceous plant tiger lily, Bulbus Lilii or Lilium tenuifolium.The property of medicine: sweet, cold.GUIXIN, lung meridian.Function cures mainly: nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.
Herba Fragariae nilerrensis: base is former: be the herb of rosaceous plant proso millet prolamin.The property of medicine: sweet, bitter; Cool.Return lung, liver, kidney channel.Function cures mainly: clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling.Main cough due to lung-heat, pertussis, aphtha of the mouth and tongue, furuncle, venom, burn and scald.
Herba Erigerontis: base is former: be root and the herb of feverfew Erigeron breviscapus (Vant.) Hand.-Mazz..The property of medicine: acrid in the mouth; Micro-hardship; Temperature.Return lung, stomach, tripe warp.Function cures mainly: expelling cold and relieving exterior syndrome, expelling wind and removing dampness, activating collaterals to relieve pain, removing food stagnancy.Main flu, rheumatic arthralgia, paralysis, stomachache, toothache, infantile malnutrition, osteomyelitis, traumatic injury.
Fructus Jujubae: base is former: be the fruit of Rhamnaceae plant Fructus Jujubae.The property of medicine: sweet; Temperature.Return spleen, stomach warp.Function cures mainly: tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind, adjusts battalion to defend, and the property of medicine.Main weakness of the spleen and stomach, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI.
Folium Nerviliae fordii: base is former: be tuber and the herb of orchid Nervilia fordii.The property of medicine: sweet; Cool; Nontoxic.Function cures mainly: nourishing the lung to arrest cough, heat-clearing and toxic substances removing, eliminating stasis to stop pain.Main pulmonary tuberculosis spitting of blood, cough due to lung-heat, stomatitis, laryngopharynx swelling and pain, scrofula, sore swollen toxin, traumatic injury.
Flos Caryophylli: base is former: be the alabastrum of dicotyledon medicine plant clove of myrtaceae.The property of medicine: acrid in the mouth; Warm in nature.Return spleen, stomach, kidney channel.Function cures mainly: warming middle-JIAO to send down the adverse QI, warming the kidney to activate YANG.Main singultus, coldness and pain in the epigastrium, lack of appetite leaf rushes down, impotence due to deficiency of the kidney, and the acid of waist knee joint is cold, carbuncle of yin nature.
Herba urariae macrostachyae: base is former: the branch and leaf penetrated for leguminous plant long fringe cat tail.The property of medicine: lightly seasoned, cool in nature.Return spleen, large intestine channel.
Function cures mainly: heat clearing away, hemostasis, removing food stagnancy, parasite killing.Main flu, cough, malaria, spits blood, spitting of blood, hematuria, traumatic hemorrhage, infantile malnutrition, filaricide.
Ramulus et Folium Psychotriae Serpentis: base is former: for Maguireothamnus speciosus is crawled the branch of Psychotria rubra (Lour.) Poir., leaf or Herb.The property of medicine: bitter, pungent, flat.Return liver, heart channel.Function cures mainly: wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain.Main rheumatic arthritis, numb hand and foot, psoas muscle labor fingerprint, sciatica, multiple carbuncle, bone tuberculosis, traumatic injury, fracture, venom.
Fructus Aurantii: base is former: be the mellow fruit nearly such as rutaceae Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Citrus aurantium Linn., fragrant circle or Citrus aurantium L. var. amara Engl..The property of medicine: bitter, sour, is slightly cold.Return lung, spleen, liver, stomach, large intestine channel.Function cures mainly: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
Fructus Crataegi: base is former: be the mature fruit of rosaceous plant Fructus Pyri Pashiae, Fructus Crataegi.The property of medicine: acid is sweet; Tepor; Nontoxic.Return spleen, stomach, liver, lung meridian.Function cures mainly: help digestion long-pending, changes the stagnant stasis of blood.Main eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, amenorrhea, puerperal abdonimal pain, lochiorrhea.
Rhizoma Humatae Tyermanni: base is former: be tuber and the herb of labiate Rhizoma Humatae Tyermanni.The property of medicine: sweet in the mouth; Property is put down.Return lung, liver, spleen channel.Function cures mainly: lung heat clearing of inducing sweat, eliminating damp, detoxifying, tonify deficiency spleen invigorating.Main anemopyretic cold, cough due to consumptive disease, jaundice, stranguria, sore swells and ache, venom
Folium Erythrinae: base is former: be the leaf of leguminous plant erythrina indica and Erythrinae Arborescentis.The property of medicine: bitter; Flat.Return stomach, intestinal warp.Function cures mainly: removing food stagnancy drives ascarid.Main infantile malnutrition; Ascariasis.
Herba Fici Simplicissimae: base is former: be the root of moraceae plants cleft palm banyan.The property of medicine: sweet; Property is put down.Function cures mainly: strengthening the spleen and tonifying the lung, circulation of qi promoting dampness removing, relaxing muscles and tendons and activating QI and blood in the collateral.Main insufficiency of the spleen edema, lack of appetite is unable, pulmonary tuberculosis cough, night sweat, leukorrhagia, puerperal agalactia, rheumatic arthralgia, edema, cirrhotic ascites, hepatitis, traumatic injury.
test example 1the clinical practice of the Chinese medicine (embodiment 5) of gained of the present invention treatment infantile malnutrition: in April ,-2010 in June, 2007, screen 320 routine infantile malnutrition patients in 6 hospitals, wherein man 175 example, female 145 example, age 2-6 year.Be divided into two groups at random, experimental group and matched group (often organizing 160 people).Experimental group man 87 example, female 73 example, age 2-6 year, 3.8 years old mean age, the course of disease 4 months-2.5 years, average course of disease 1.6 years.Matched group man 88 example, female 72 example, age 2-6 year, 3.7 years old mean age, the course of disease 5 months-2.5 years, average course of disease 1.5 years.Above two groups of patients compare there was no significant difference (P > 0.05) in age composition, sex composition, the course of disease etc., and case-data has comparability.
Diagnostic criteria
Draft with " Pediatrics of Chinese Medicine " according to the diagnostic criteria of infantile malnutrition in " disease of tcm Standardization of diagnosis and curative effect " that management board of national institute of traditional Chinese medicine promulgates for 1994.Clinical manifestation: (1) diet is abnormal, defecate the obviously dysfunction of spleen and stomach person such as uncomfortable or gastral cavity abdominal distention; (2) emaciated physique, height, body weight are below normal value, and decrease beyond more than 1 standard deviation, lusterless complexion, hypotrichosis is withered and yellow, and severe patient dries up; (3) have lassitude concurrently, or hot-tempered, irritable, or eyebrow brush eye is rubbed in happiness, or suck finger and grind one's teeth in sleep, light red tongne, tongue are yellowish and greasy, soft and thready pulse and sliding; (4) improper feeding or drinking and eating irregularly and history of becoming thin for a long time is after being ill had; (5) anemia person, hemoglobin and erythrocytopenia; (6) body is looked into and is not found positive sign; (7) fever caused by exogenous pathogens, infectious disease, diarrhea due to damp-heat, congenital diseases, malignant tumor etc. are got rid of.All possess (6), (7) item and (1), (2), (3), (4), in (5) item any two namely diagnosable.
Therapeutic Method
Experimental group uses gained of the present invention to treat the Chinese medicine of infantile malnutrition, using method: oral, one-year-old with 5 milliliters next time, 1 ~ 2 years old one time 8 milliliters, 3 ~ 5 years old one time 10 milliliters, within 5 years old, with last 15 milliliters, 3 times on the one 15 days is a course for the treatment of.Matched group uses the Drug therapys such as valiant fighter's GANJI SAN, Xiaoerkang granules, infantile malnutrition sugar, within 15 days, is a course for the treatment of.Comparison of therapeutic is carried out after two groups of patients all treat three courses for the treatment of.
Curative effect situation criterion
Curative effect judging standard is drafted with reference to " disease of tcm Standardization of diagnosis and curative effect ".Cure: body weight increases, close to normal health children's body weight, various transference cure, laboratory checking index recovers normal; Take a turn for the better: body weight increases to some extent, spirit, appetite and other symptoms are improved; Invalid: symptom and sign are all unchanged.Total effectively comprising cures and takes a turn for the better.After treating three courses for the treatment of, result is as shown in table 1.
Table 1: the Chinese medicine compliance test result of gained treatment infantile malnutrition of the present invention
efficacy analysis:as can be seen from Table 1, the experimental group using gained of the present invention to treat the Chinese medicine of infantile malnutrition cures 112 examples, and take a turn for the better 45 examples, invalid 3 examples; And matched group cures 42 examples, take a turn for the better 78 examples, invalid 40 examples.The total effective rate of experimental group reaches 98.13%, and the total effective rate of matched group is 75%.Experiment shows, experimental group total effective rate is obviously better than matched group, and its curative effect increases substantially, and cure rate significantly promotes, and inefficiency significantly reduces, and two groups of comparing differences have significance.
The present invention for primary raw material medicine, makes the Chinese medicine for the treatment of infantile malnutrition with pure natural Chinese herbal medicine such as the Rhizoma Atractylodis Macrocephalae, Herba mazi japonici, Cortex Annesleae Fragrantis and Herba Lobeliae Chinensiss.Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI in side, dampness diuretic, hidroschesis, antiabortive.Herba mazi japonici heat-clearing and toxic substances removing, dampness removing is treating stranguria, spleen invigorating removing food stagnancy.Cortex Annesleae Fragrantis promoting the circulation of QI to relieve pain; Help digestion antidiarrheal.Herba Lobeliae Chinensis heat clearing away, removing food stagnancy.Bulbus Lilii nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Herba Fragariae nilerrensis clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling.Herba Erigerontis expelling cold and relieving exterior syndrome, expelling wind and removing dampness, activating collaterals to relieve pain, removing food stagnancy.Fructus Jujubae tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind, adjusts battalion to defend, and the property of medicine.Folium Nerviliae fordii nourishing the lung to arrest cough, heat-clearing and toxic substances removing, eliminating stasis to stop pain.Flos Caryophylli warming middle-JIAO to send down the adverse QI, warming the kidney to activate YANG.Herba urariae macrostachyae heat clearing away, hemostasis, removing food stagnancy, parasite killing.Ramulus et Folium Psychotriae Serpentis wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain.Fructus Aurantii dispelling the stagnated QI, row expectorant, removing food stagnancy.Hawthorn digesting amasss, and changes the stagnant stasis of blood.Rhizoma Humatae Tyermanni is induced sweat lung heat clearing, eliminating damp, detoxifying, tonify deficiency spleen invigorating.Folium Erythrinae removing food stagnancy drives ascarid.Herba Fici Simplicissimae strengthening the spleen and tonifying the lung, circulation of qi promoting dampness removing, relaxing muscles and tendons and activating QI and blood in the collateral.All medicines share, and have spleen invigorating removing food stagnancy, clearing away heart-fire for tranquillization, take a tonic or nourishing food to build up one's health taste, effect that invigorating qi and benefiting blood, warming the kidney to activate YANG, relaxing muscles and tendons and activating QI and blood in the collateral, parasite killing drive ascarid, inducing diuresis to remove edema, yin nourishing tonify deficiency, and can adjust spleen and stomach function, recover function, clinical efficacy is definite.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. treat the Chinese medicine of infantile malnutrition, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Rhizoma Atractylodis Macrocephalae 10-16, Herba mazi japonici 8-15, Cortex Annesleae Fragrantis 7-12, Herba Lobeliae Chinensis 5-13, Bulbus Lilii 11-15, Herba Fragariae nilerrensis 6-12, Herba Erigerontis 8-14, Fructus Jujubae 12-16, Folium Nerviliae fordii 7-11, Flos Caryophylli 10-13, Herba urariae macrostachyae 8-15, Ramulus et Folium Psychotriae Serpentis 6-14, Fructus Aurantii 9-11, Fructus Crataegi 11-16, Rhizoma Humatae Tyermanni 4-6, Folium Erythrinae 7-12, Herba Fici Simplicissimae 9-13.
2. the Chinese medicine for the treatment of infantile malnutrition as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Rhizoma Atractylodis Macrocephalae 12-15, Herba mazi japonici 10-13, Cortex Annesleae Fragrantis 9-11, Herba Lobeliae Chinensis 7-10, Bulbus Lilii 12-14, Herba Fragariae nilerrensis 8-11, Herba Erigerontis 9-12, Fructus Jujubae 13-15, Folium Nerviliae fordii 8-10, Flos Caryophylli 11-12, Herba urariae macrostachyae 10-12, Ramulus et Folium Psychotriae Serpentis 8-12, Fructus Aurantii 9.5-10.5, Fructus Crataegi 12-14, Rhizoma Humatae Tyermanni 4.5-5.5, Folium Erythrinae 9-11, Herba Fici Simplicissimae 10-12.
3. the Chinese medicine for the treatment of infantile malnutrition as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: the Rhizoma Atractylodis Macrocephalae 13, Herba mazi japonici 11, Cortex Annesleae Fragrantis 10, Herba Lobeliae Chinensis 9, Bulbus Lilii 13, Herba Fragariae nilerrensis 10, Herba Erigerontis 10, Fructus Jujubae 14, Folium Nerviliae fordii 9, Flos Caryophylli 11.5, Herba urariae macrostachyae 11, Ramulus et Folium Psychotriae Serpentis 10, Fructus Aurantii 10, Fructus Crataegi 13, Rhizoma Humatae Tyermanni 5, Folium Erythrinae 10, Herba Fici Simplicissimae 11.
4. the Chinese medicine of the treatment infantile malnutrition as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment infantile malnutrition is made pharmaceutically acceptable syrup, and the preparation method of described syrup is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10-15g Testa Tritici skin, and Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140-180 DEG C, smoke 10-30 minute, take out, cool, sieve removes Testa Tritici skin, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6-8 hour (preferably baking 7 hours), take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11-14 times (preferred amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight) of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into 1:1 medicinal liquid;
(4) sucrose and antiseptic are joined in step (3) gained medicinal liquid, are stirred to dissolve, boil, let cool, thin up, make sucrose concentration be 70%(g/mL), concentration of preservatives is 0.2%(g/mL), stir evenly, fill, to obtain final product.
5. the preparation method of the Chinese medicine syrup for the treatment of infantile malnutrition as claimed in claim 4, it is characterized in that, in step (1), every 100g Fructus Crataegi adds 13g Testa Tritici skin.
6. the preparation method of the Chinese medicine syrup for the treatment of infantile malnutrition as claimed in claim 4, it is characterized in that, step puts it in the Electric heat oven of 160 DEG C in (1).
7. the preparation method of the Chinese medicine syrup for the treatment of infantile malnutrition as claimed in claim 4, it is characterized in that, step smokes 20 minutes in (1).
8. the preparation method of the Chinese medicine syrup for the treatment of infantile malnutrition as claimed in claim 4, it is characterized in that, described in step (4), antiseptic is sodium benzoate or potassium sorbate.
9. the Chinese medicine of the treatment infantile malnutrition as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment infantile malnutrition is made pharmaceutically acceptable pill, and the preparation method of described pill is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10-15g Testa Tritici skin (preferably every 100g Fructus Crataegi adds 13g Testa Tritici skin), Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140-180 DEG C and (preferably put it in the Electric heat oven of 160 DEG C), smoke 10-30 minute (preferably smoking 20 minutes), take out, cool, sieve removes wheat bran, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6-8 hour (preferably baking 7 hours), take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11-14 times (preferred amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight) of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into the clear paste (preferred filtrate is condensed into the clear paste that relative density is 1.22) that relative density is 1.18-1.24, then refined honey is added, every 100kg clear paste adds the preferred every 100kg clear paste of refined honey 160-200kg(and adds refined honey 180kg), make honeyed pill, the weight of every ball is 0.1-0.2 gram (preferably the weight of every ball is 0.15 gram).
10. the Chinese medicine of the treatment infantile malnutrition as described in as arbitrary in claims 1 to 3, it is characterized in that, the Chinese medicine of this treatment infantile malnutrition is made pharmaceutically acceptable thick paste agent, and the preparation method of described thick paste agent is:
(1) Fructus Crataegi is under agitation sprayed water and makes it moistening, then under agitation add Testa Tritici skin to mix and stir, every 100g Fructus Crataegi adds 10-15g Testa Tritici skin (preferably every 100g Fructus Crataegi adds 13g Testa Tritici skin), Testa Tritici skin is attached on Fructus Crataegi equably, puts it in the Electric heat oven of 140-180 DEG C and (preferably put it in the Electric heat oven of 160 DEG C), smoke 10-30 minute (preferably smoking 20 minutes), take out, cool, sieve removes wheat bran, be ground into coarse powder, cross 40 mesh sieves;
(2) all the other except Fructus Crataegi 16 taste crude drug is put into the Electric heat oven of 65 DEG C, toast 6-8 hour (preferably baking 7 hours), take out, cool, be ground into coarse powder, cross 40 mesh sieves;
(3) by step (1) and the mixing of step (2) gained coarse powder, add water, amount of water is 11-14 times (preferred amount of water is 12 times of step (1) and step (2) gained coarse powder gross weight) of step (1) and step (2) gained coarse powder gross weight, supersound extraction three times, each ultrasonic time is 1.2 hours, by three extracting solution mixing, filter, filtrate is condensed into the thick paste (preferred filtrate is condensed into the thick paste that relative density is 1.32) that relative density is 1.31-1.35, add refined honey, every 100kg thick paste adds the preferred every 100kg thick paste of refined honey 150-180kg(and adds refined honey 170kg), micro-refining, foam removal, seal and get final product in dress aseptic bottle.
CN201510258900.0A 2015-05-21 2015-05-21 Traditional Chinese medicine preparation for treating infantile malnutrition and preparation method thereof Pending CN104815180A (en)

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Application publication date: 20150805