Summary of the invention
Based on this, be necessary to provide a kind of test strips to place the small-sized Handheld analysis easy, equipment size is little, easy to use.
A kind of Handheld analysis, comprises test paper cutting ferrule and box body,
Described test paper cutting ferrule inside has the cell body placing test strips, and described test card cover has passage, and the position of described passage corresponds to the position of described cell body;
Described box body has the opening inserted for test card cover, described box body has the window for placing display element, described box body also has illumination component, imaging apparatus and detection system, described illumination component, imaging apparatus are connected to described detection system, there is in described box body the draw-in groove portion for placing test paper cutting ferrule, described draw-in groove portion and described illumination component be arranged in parallel, and described illumination component is toward described draw-in groove portion.
Wherein in an embodiment, described detection system has imaging apparatus, processing module, power supply, catoptron and signal transmitting and receiving element, described power electric is connected to described processing module, described imaging apparatus, illumination component, signal transmitting and receiving element, display element are connected to described processing module, and the chien shih three that described catoptron is positioned at described imaging apparatus and draw-in groove portion forms reflected light path.
Wherein in an embodiment, described test paper cutting ferrule comprises main part and cover body part;
The upper surface of described main part is protruding with multiple projection, and multiple projection is configured for the cell body that test strips established by card, and described main part is connected with first handle, and on the lower surface and two side surface direction of main part, the size of first handle is relatively outstanding;
Described cover body part is connected with second handle, and on the upper surface and two side surface direction of cover body part, the size of second handle is relatively outstanding, and the lower surface of described cover body part is fit to the upper surface of described main part and first handle is matched with second handle.
Wherein in an embodiment, the size of described cover body part is matched with described main part, described cover body part has passage and is formed into picture mouth, and the size of described passage is less than the size of described cell body, and the position of the passage of described cover body part corresponds to the cell body position of described main part.
Wherein in an embodiment, the upper surface of the cover body part of described test paper cutting ferrule has the groove for placing release.
Wherein in an embodiment, described display element comprises LCDs and touch-screen, and the upper surface of described box body has described window, and described LCDs is embedded in the window of described box body, and described touch-screen is stacked and placed on the top of described LCDs.
Wherein in an embodiment, described illumination component is LED lamp bar, and described test paper cutting ferrule is elongated, and the draw-in groove portion in described box body is strip.
Wherein in an embodiment, described signal transmitting and receiving element has wireless signal antenna, gps antenna, and described wireless signal antenna, gps antenna are all connected to described processing module.
Wherein in an embodiment, the opening of described box body has baffle plate and elastomeric element, the size of described baffle plate is matched with the size of the window of described box body, one side of described baffle plate is coupling in the window edge of described box body by rotating shaft, and described elastomeric element is connected between described box body and baffle plate.
Another object of the present invention is to provide a kind of detection method.
Based on a detection method for described Handheld analysis, comprise the steps:
Test strips to be detected is inserted in box body by test card cover, described test paper cutting ferrule is parallel to illumination component and places, and make the passage of described test paper cutting ferrule towards the illumination component in box body, make the uniform illumination of described illumination component irradiate the test strips in the passage of described test paper cutting ferrule;
Luminous by display element manipulation illumination component, detection system obtains the ELISA test strip face image in test paper cutting ferrule passage, detection system process image event memory, result is sent by display element manipulation detection system.
The Handheld analysis that the present invention relates to, by the cooperation of test paper cutting ferrule and box body, and test card cover possesses unified external dimensions, different inner structures, the test strips of multiple different size can be coordinated, therefore, the design of general purpose card slot makes Handheld analysis of the present invention be suitable for more extensively, uses workplace more extensive.
The Handheld analysis that the present invention relates to, by the design of processing module, coordinate process software (detection modules of internal calibration, detection data), make Handheld analysis operationally, the processing power of image and correction capability are significantly improved, equipment use intelligent operating system, by the design of touch-screen and LCDs, makes operation more easy.
The Handheld analysis that the present invention relates to, physical dimension is mainly limited to display device and the light path part of equipment, but display device size cannot reduce, and only has and reduces equipment size by trying every possible means in light path.In the light path of (a) analyser, in order to reduce the height of equipment (box body), make equipment (box body) compacter, the upper casing of equipment (box body) is designed to inclined-plane near the one end in draw-in groove portion, catoptron and test paper cutting ferrule are angle, and the top of catoptron tilts towards camera direction, the assembly that placement catoptron this part is larger, catoptron is placed on separately on mirror support, then the inclined-plane of mirror support stationary mirror is parallel with the inclined-plane of equipment upper casing and be close to, and so significantly can reduce the height of equipment.B the longer axis parallel of () illuminating lamp bar is in the major axis of catoptron, test card is enclosed within tray interior and illuminating lamp bar be arranged in parallel, the space that test paper cutting ferrule and illumination component are taken in box body is little, the size of whole box body that makes further reduces, and makes whole equipment (Handheld analysis) easy to carry.
The Handheld analysis that the present invention relates to, the collection of image uses imaging apparatus, what imaging apparatus adopted is high definition CMOS camera, pictures taken is clear, make the analysis of processing module more quick, movement images required time is short, obtains a result quicker, and the processing power of image is strong, makes the accuracy of testing result greatly improve.
The detection method of the Handheld analysis that the present invention relates to, does not need in testing process first to insert blank test strips at every turn.Two kinds of situations are only only had to need to read blank card: 1, in production of machinery process, need to read blank test strips, the illumination distribution curve storage detecting the machine makes reference; 2, the product of new batch, needs to read blank test strips, to distinguish the gray difference of different batches test strips substrate.
Accompanying drawing explanation
Fig. 1 is the box body schematic top plan view of embodiment of the present invention Handheld analysis;
Fig. 2 is the box body right side schematic view of embodiment of the present invention Handheld analysis;
Fig. 3 be embodiment of the present invention Handheld analysis box body on the left of schematic diagram;
Fig. 4 be embodiment of the present invention Handheld analysis box body on rear side of schematic diagram;
Fig. 5 is the test paper cutting ferrule schematic top plan view of embodiment of the present invention Handheld analysis;
Fig. 6 is the test paper cutting ferrule schematic side view of embodiment of the present invention Handheld analysis;
Fig. 7 is the test paper cutting ferrule exploded perspective view of embodiment of the present invention Handheld analysis;
Fig. 8 is that the box body of embodiment of the present invention Handheld analysis coordinates schematic diagram with test paper cutting ferrule;
Fig. 9 is upper casing and the lower casing exploded perspective view of the box body of embodiment of the present invention Handheld analysis;
Figure 10 is the tray interior element exploded perspective view of embodiment of the present invention Handheld analysis;
Figure 11 is the principle of work schematic diagram of embodiment of the present invention Handheld analysis.
Description of reference numerals
1, touch-screen; 2, LCDs; 3, display/panel bracket; 4, mainboard; 5, microphone; 6,3G antenna; 7, camera bracket; 8, battery; 9, loudspeaker; 10, WIFI antenna; 11, gps antenna; 12, catoptron; 13, LED lamp bar; 14, mirror support; 15, draw-in groove portion; 16, camera dustproof glass; 17, camera; 18, camera bracket fixed screw; 19, upper casing; 20, key button; 21, key plastic strip; 22, volume adjusting button; 23, volume key plastic strip; 24, lower casing fixed screw; 25, foot pad; 26, torsion spring; 27, rotating shaft; 28, test paper toll bar; 29, Quick Response Code card; 30, cover body part; 31, test strips; 32, main part; 33, U-shaped is protruding; 34, strip projected parts; 35, first handle; 36, second handle; 37, passage; 38, groove; 39, window; 40, lower casing; 41, draw-in groove; 42, elastic arm.
Embodiment
For the ease of understanding the present invention, below with reference to relevant drawings, the present invention is described more fully.Preferred embodiment of the present invention is given in accompanying drawing.But the present invention can realize in many different forms, is not limited to embodiment described herein.On the contrary, provide the object of these embodiments be make the understanding of disclosure of the present invention more comprehensively thorough.
It should be noted that, when element is called as " being fixed on " another element, directly can there is element placed in the middle in it on another element or also.When an element is considered to " connection " another element, it can be directly connected to another element or may there is centering elements simultaneously.
Unless otherwise defined, all technology used herein and scientific terminology are identical with belonging to the implication that those skilled in the art of the present invention understand usually.The object of term used in the description of the invention herein just in order to describe specific embodiment, is not intended to be restriction the present invention.Term as used herein "and/or" comprises arbitrary and all combinations of one or more relevant Listed Items.
A kind of Handheld analysis, shown in Fig. 1-Figure 10, comprises test paper cutting ferrule and box body.
Shown in Fig. 5-Fig. 7, described test paper cutting ferrule inside has the cell body placing test strips 31, and described test card cover has passage 37, and the position of described passage 37 corresponds to the position of described cell body;
In the present embodiment, described test paper cutting ferrule comprises main part 32 and cover body part 30; The upper surface of described main part 32 is protruding with multiple projection, multiple projection is configured for the cell body that test strips 31 established by card, described main part 32 is connected with first handle 35, the size on the lower surface in first handle 35 opposing body portion 32 and two sides outstanding (note: in Fig. 5-Fig. 8 35,36 transpositions);
Described cover body part 30 is connected with second handle 36, and the size of second handle 36 relatively on the upper surface of cover body part 30 and two sides is given prominence to, and the lower surface of described cover body part 30 is fit to the upper surface of described main part 32 and first handle 35 is matched with second handle 36.The size of described cover body part 30 is matched with described main part 32, described cover body part 30 has passage 37 and is formed into picture mouth, the size of described passage 37 is less than the size of described cell body, and the position of the passage 37 of described cover body part 30 corresponds to the cell body position of described main part 32.
The upper surface of the cover body part 30 of described test paper cutting ferrule has the groove 38 for placing release (Quick Response Code card 29), and there are the passage 37 of taking pictures for sample and the groove 38 for placing 2 D code information in test paper cutting ferrule surface.Quick Response Code, comprises the detection model of test strips 31, sequence number, date of manufacture, batch number, reference tape information.Test paper cutting ferrule inside comprises a test strips 31, and test strips 31 detects the carrier of sample as user.Detecting sample such as blood sample etc. is added in test strips 31, and the antigen in sample or antibody spread and completes chromogenic reaction in test strips 31.
Described main part 32 is elongated, and the cell body of described main part 32 is elongated, and the longer axis parallel of the major axis of the cell body of main part 32 and described main part 32.Passage 37 in described cover body part 30 is elongated, the major axis of described cover body part 30 upper channel 37 and the longer axis parallel of described main part 32 cell body, and the length of described cover body part 30 upper channel 37 is less than the length of described main part 32 cell body.
Two ends of described main part 32 upper surface have the opening of U-shaped projection 33, two U-shaped projections 33 in opposite directions, and two described U-shapeds protruding 33 form described cell body.There is between two U-shaped projections 33 axis that at least two strip projected parts 34, two strip projected parts 34 are parallel to protruding 33 places of two U-shapeds.Two strip projected parts 34 are distributed in the both sides of the axis at protruding 33 places of two U-shapeds.The side of described main part 32 has draw-in groove 41.
Described cover body part 30 is blocked with described main part 32 formula of establishing and is connected.Described first handle 35 is integrally connected to described main part 32.Described second handle 36 is integrally connected to described cover body part 30.
Shown in Fig. 1-Fig. 4 and Fig. 8-Figure 10, described box body is divided into upper casing 19 and lower casing 40, upper casing 19 and lower casing 40 connect and compose box body removably, described box body has the opening (test paper toll bar 28) inserted for test card cover, in described box body, there is detection system, display element and illumination component, described detection system has imaging apparatus, processing module, power supply, catoptron 12 and signal transmitting and receiving element, described power electric is connected to described processing module, described imaging apparatus, illumination component, signal transmitting and receiving element, display element is connected to described processing module, there is in described box body the draw-in groove portion 15 (also namely establishing the draw-in groove of test paper cutting ferrule for card) for placing test paper cutting ferrule, described draw-in groove portion 15 be arranged in parallel with described illumination component, the uniform illumination of described illumination component is made to irradiate the test strips 31 in described test paper cutting ferrule passage 37.Described box body has the window for placing described display element, and in the present embodiment, described upper casing 19 has described window, the chien shih three that described catoptron 12 is positioned at described imaging apparatus and draw-in groove portion 15 forms reflected light path.Because test paper cutting ferrule needs the bottom (in draw-in groove portion 15) lying in box body, catoptron 12 needs with test strips 31 (being also test paper cutting ferrule) angled, guarantees that imaging completely can be caught on camera 17 collection.In order to reduce the height of equipment (box body), make equipment (box body) compacter, the upper casing 19 of equipment (box body) is designed to inclined-plane near the one end in draw-in groove portion 15, the assembly that placement catoptron 12 this part is larger, effectively reduce the height of equipment like this, catoptron 12 and test paper cutting ferrule are angle, and the top of catoptron 12 tilts towards camera 17 direction.Described processing module has mainboard 4, and described power supply is battery 8, is arranged at the bottom of box body, i.e. the bottom position of lower casing 40.The inside in the draw-in groove portion 15 in box body has elastic arm 42, described elastic arm coordinates with the draw-in groove 41 on the main part 32 of described test paper cutting ferrule, can stablize in order to ensure test paper cutting ferrule is plugged in box body, adds the design of draw-in groove 41 and elastic arm 42 among the structure in test paper cutting ferrule and draw-in groove portion 15.The matching design of elastic arm 42 and draw-in groove 41, can guarantee on the one hand clamping test paper cutting ferrule, has small sense of touch on the other hand, point out user's plug-in card to put in place when card is inserted into.
Also can have calibration card at tray interior near the side, draw-in groove portion 15 of placing test paper cutting ferrule, calibration card is made up of the GTG band of different gray-scale value, is used for calibrating the exposure value that camera 17 is taken pictures.
The opening of described box body has baffle plate and elastomeric element, the size of described baffle plate is matched with the size of the window of described box body, one side of described baffle plate is coupling in the window edge of described box body by rotating shaft 27 (test card door pivot 27), and described elastomeric element is connected between described box body and baffle plate.In the present embodiment, by the elastomeric element of the opening part of box body and the cooperation of baffle plate, form elastic opening (test paper toll bar 28), the stopping screens that the first handle 35 that elastic opening and test card put and the surface of second handle 36 form relative test paper cutting ferrule outstanding designs, guarantee that test card cover is inserted and secured on assigned address, described in the present embodiment, elastomeric element is torsion spring 26 (test paper toll bar torsion spring 26).
In the present embodiment, cross-sections match on the shape of the opening of described box body and the long axis direction of described test paper cutting ferrule makes test paper cutting ferrule can insert in box body from opening part, also namely rectangle is, the opening of described box body is recessed into relative to the side of box body, also namely the side of box body has recessed mouth, the surface of recessed mouth has described opening, and the size of opening is less than the size of recessed mouth, also namely the surrounding of opening has platform, the part that the first handle 35 that this platform is matched with test paper cutting ferrule is given prominence to second handle 36, this design is in order to ensure after test card cover inserts box body, the opening of box body does not leave direct gap, play dust-proof and light-shading effect.
Described processing module has for internal calibration, the detection module detecting data, namely detects App, detects the measuring ability that App realizes colloidal gold test paper card, internal calibration function, detection data management etc.Described display element comprises LCDs 2 and touch-screen 1, and the upper surface of described box body has described window, and described LCDs 2 is embedded in the window of described box body, and described touch-screen 1 is stacked and placed on the top of described LCDs 2.
Described illumination component is LED lamp bar 13, and LED lamp bar 13 has 6 LED lamp bead (providing Uniform Illumination to test strips 31 in the inside of equipment and box body), and described test strips 31 is overlapped elongated, and the draw-in groove portion 15 in described box body is in strip.
Described signal transmitting and receiving element has 3G antenna 6, wireless signal antenna (WIFI antenna 10), gps antenna 11, and described 3G antenna 6, wireless signal antenna (WIFI antenna 10), gps antenna 11 are all connected to described processing module.
Further, described tray interior has imaging apparatus support, and described imaging apparatus support has described chamber, and described imaging apparatus has camera 17, and described camera 17 is CMOS high-definition camera 17 (for gathering the photo of test strips 31); Described imaging apparatus is arranged in the chamber of described imaging apparatus support, and described shooting is toward the through hole of described chamber.Described imaging apparatus support is also camera bracket 7 (plastic material, cavity in the middle part of support 7 is used for fixing the bottom of camera, also there is one piece of groove the below of display/panel bracket 3, be used for placing and paste camera, the upper and lower sides of such camera all has support structure, guarantee that camera is stablized), the lower casing 40 of box body is fixed on by camera bracket fixed screw 18.
Further, described display element comprises LCDs 2 and touch-screen 1, and described touch-screen 1 is capacitance touch screen 1, and the upper surface of described box body has described window, described LCDs 2 is embedded in the window of described box body, and described touch-screen 1 is stacked and placed on the top of described LCDs 2.
Further, also comprise display/panel bracket 3 (metal material), described display/panel bracket 3 is arranged in described box body, and described touch-screen 1, LCDs 2 are stacked and placed on described display/panel bracket 3 successively.
Further, also comprise transparent dust-proof element, described dustproof element is arranged at the through hole of described box body chamber, and described dustproof element is camera dustproof glass 16, is arranged at the front end of camera 17.
Further, described mirror support 14 is arranged in described box body, and described catoptron 12 is connected on described mirror support 14.
Further, described catoptron 12 and test paper cutting ferrule (test strips) and camera 17 three have a certain degree restriction relation, make camera 17 photocentre vertical with test paper cutting ferrule (test strips) imaging in catoptron 12.Such design suitably can adjust relative angle according to structure, reduces the height of equipment.Further, also comprise sound and play and receiving element, sound is play and receiving element has described loudspeaker 9 and microphone 5, and described loudspeaker 9 and microphone 5 are connected to described processing module.In the present embodiment, the side of described box body is also provided with volume adjusting button 22 and key button 20, volume adjusting button 22 connection handling module, and the inner side of volume adjusting button 22 is to there being volume key plastic strip 23.Key button 20 connection handling module, the inner side of key button 20 is to there being key plastic strip 21.
Further, bottom the lower casing 40 of described box body, there is multiple lower casing fixed screw 24, form box body for fixing lower casing 40 with upper casing 19, and the bottom of lower casing 40 has multiple foot pad 25.
The present embodiment also provides a kind of detection method based on Handheld analysis.
Based on a detection method for described Handheld analysis, comprise the steps:
Gray-scale value reference data when processing module is completely normal by the illumination component of imaging apparatus acquisition analyser, and store; Blank test strips 31 is put into the cell body of test paper cutting ferrule, and by the passage 37 of detection faces towards test paper cutting ferrule, insert in box body by test card cover, gray-scale value reference data when processing module is completely normal by the illumination component of imaging apparatus acquisition analyser, and store;
Add and detect sample to test strips 31, test strips 31 to be detected is inserted in box body by test card cover, described test paper cutting ferrule is parallel to illumination component and places, and by the passage 37 of detection faces towards test paper cutting ferrule, inserts in the opening of box body by the test card cover being equipped with test strips 31, luminous by display element manipulation illumination component, test strips 31 detection faces image in test paper cutting ferrule passage 37 is reflexed to imaging apparatus by catoptron 12, after imaging apparatus imaging, image is sent to processing module, processing module process image event memory, numeric ratio is utilized comparatively to identify the background area data of adding and detecting the test strips 31 after sample, background area data are compared with graphic based data, analyze background area lighting result value, corresponding detection sample concentration information is converted to by numerical value Processing Algorithm, result is stored in the machine, and result is sent by signal transmitting and receiving element (WIFI antenna 10) by display element manipulation processing module.
The Handheld analysis that the present embodiment relates to, by the design of processing module, coordinate process software (detection modules of internal calibration, detection data), make Handheld analysis operationally, the processing power of image and correction capability are significantly improved, equipment use intelligent operating system, by the design of touch-screen and LCDs, makes operation more easy.
The Handheld analysis that the present embodiment relates to, physical dimension is mainly limited to display device and the light path part of equipment, but display device size cannot reduce, and only has and reduces equipment size by trying every possible means in light path.In the light path of (a) analyser, in order to reduce the height of equipment (box body), make equipment (box body) compacter, the upper casing of equipment (box body) is designed to inclined-plane near the one end in draw-in groove portion, catoptron and test paper cutting ferrule are angle, and the top of catoptron tilts towards camera direction, the assembly that placement catoptron this part is larger, catoptron is placed on separately on mirror support, then the inclined-plane of mirror support stationary mirror is parallel with the inclined-plane of equipment upper casing and be close to, and so significantly can reduce the height of equipment.B the longer axis parallel of () illuminating lamp bar is in the major axis of catoptron, test card is enclosed within tray interior and illuminating lamp bar be arranged in parallel, the space that test paper cutting ferrule and illumination component are taken in box body is little, the size of whole box body that makes further reduces, and makes whole equipment (Handheld analysis) easy to carry.
The Handheld analysis that the present embodiment relates to, the collection of image uses imaging apparatus, what imaging apparatus adopted is high definition CMOS camera, pictures taken is clear, make the analysis of processing module more quick, movement images required time is short, obtains a result quicker, and the processing power of image is strong, makes the accuracy of testing result greatly improve.
The device interior cavity of the hand-held analysis that the present embodiment relates to is separated, and by parts such as cavity, each supports, reduces dust to the impact of device interior cleanliness factor.
The hand-held analysis that the present embodiment relates to, by the elastomeric element of the opening part of box body and the cooperation of baffle plate, form elastic opening, the stopping screens that the first handle that elastic opening and test card put and the surface of second handle form relative test paper cutting ferrule outstanding designs, guarantee that test card cover is inserted and secured on assigned address, equipment possesses certain anti-seismic performance, can mobile device in testing process.
The detection method of the Handheld analysis that the present embodiment relates to, does not need in testing process first to insert blank test strips at every turn.Two kinds of situations are only only had to need to read blank card: 1, in production of machinery process, need to read blank test strips, the illumination distribution curve storage detecting the machine makes reference; 2, the product of new batch, needs to read blank test strips, to distinguish the gray difference of different batches test strips substrate.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.