CN104800742A - Chinese medicinal composition for treating rhinitis and preparation method thereof - Google Patents
Chinese medicinal composition for treating rhinitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating rhinitis, which is mainly prepared from the following raw material medicines in parts by mass: 12 to 18 parts of luffa stem, 10 to 16 parts of shrubby woodfordia root and flower, 13 to 20 parts of codonopsis pilosula, 9 to 15 parts of angelica dahurica, 10 to 17 parts of biond magnolia flower, 9 to 14 parts of elettaria cardamomum, 7 to 13 parts of andrographis paniculata, 11 to 16 parts of chrysanthemum, 10 to 14 parts of centipeda minima, 7 to 12 parts of green-vitriol, 9 to 13 parts of radix puerariae, 10 to 14 parts of vicia unijuga, 9 to 14 parts of loquat leaf, 11 to 15 parts of hypericum attenuatum, 9 to 15 parts of variegated solomonseal rhizome and 8 to 16 parts of asarum sieboldii. The Chinese medicinal composition has a good curative effect and a high recovery rate, prevents relapse and has the outstanding curative effect on both acute and chronic rhinitis; the prescription completely accords with the traditional Chinese medicine principle; the Chinese medicinal composition has effects of clearing away heat to dispel wind, relieving stuffy nose, relieving pain and the like; the Chinese medicinal composition is prepared from the traditional Chinese medicine materials; the prepared product is safe and reliable, has few adverse effects and can be taken for a long time.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition for the treatment of rhinitis and preparation method thereof.
Background technology
Rhinitis be nasal mucosa or sub-mucosal tissues because viral infection, courses of infection, stimulus object stimulation etc., cause nasal mucosa or sub-mucosal tissues impaired, caused acute or chronic inflammatory disease.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, ooze out, hypertrophy, atrophy or necrosis etc.Rhinitis can be divided into acute, chronic, atrophic, allergy etc. are several.The four seasons all can occur, especially more with climate variability morbidity in season.Wherein allergic rhinitis (allergic rhinitis) is the most common in spring.Rhinitis Symptoms has a variety of, and the kind according to rhinitis is different, and Rhinitis Symptoms is also different, and Rhinitis Symptoms mainly contains nasal obstruction, watery nasal discharge, sneeze, the headache of rhinitis type, giddy etc., and nasal obstruction feature is intermittent.By day, sky heat, work or motion time nasal obstruction alleviate, and night, sit quietly or cold time nasal obstruction increase the weight of.Another feature of nasal obstruction is alternately.The cardinal symptom of rhinitis is nasal obstruction, so control rhinitis nasal mucosa film contracting agent, as medicines such as naphazolines, if can not maintain ventilation after every medication, then needs to carry out operative treatment, as concha nasalis excision.
Publication No. CN 102988560 A(application number 201210577663.0) Chinese patent literature disclose a kind of medicine for rhinitis, raw material comprises Fructus Xanthii (stir-fry) 16-20 part, Herba Schizonepetae 10-14 part, Rhizoma Chuanxiong 8-10 part, Herba Menthae 6-12 part, Radix Saposhnikoviae 4-8 part, Cortex Phellodendri 5-9 part, Herba Asari 6-10 part, Herba Pogostemonis 6-12 part, Herba Centipedae 3-7 part, Spica Prunellae 6-8 part, Ramulus Cinnamomi 6-10 part, Radix Bupleuri 4-8 part, Radix Gentianae 3-5 part.Publication No. CN 103690641 A(application number 201210364643.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of rhinitis, consist of Herba Xanthii 3 ~ 18g, Flos Magnoliae 3 ~ 18g, Radix Rubiae 5 ~ 25g, Flos Lonicerae 15 ~ 45g, Flos Chrysanthemi 5 ~ 30g.Publication No. CN 103479873 A(application number 201310467854.6) Chinese patent literature disclose a kind of rhinitis and lead to loose formula, comprehensively make with Fructus Xanthii 30-40 part, Radix Angelicae Dahuricae 30-40 part, Herba Menthae 30-40 part, Rhizoma Cimicifugae 30-40 part, Radix Paeoniae 10-20 part, Radix Ophiopogonis 10-20 part, Radix Scutellariae 20-30 part, Radix Saposhnikoviae 20-30 part, Rhizoma Chuanxiong 10-20 part, Radix Ginseng 20-30 part, Radix Glycyrrhizae 10-20 part.
Western medicine rhinitis can only reach the effect of temporary relief of symptoms sign, fundamentally can not treat this disease, and often take antibiotics, easily make bacterial dissociation, develop immunity to drugs.The formula of Chinese traditional treatment rhinitis has many, but therapeutic effect still has much room for improvement, and needs to study further.
Summary of the invention
For the defect of prior art, the object of this invention is to provide and a kind ofly prepare Chinese medicine composition of simple, reliable and effective treatment rhinitis and preparation method thereof.
Technical scheme of the present invention is:
The Chinese medicine composition for the treatment of rhinitis, is prepared from primarily of following bulk drugs, is mass parts: Ramulus Luffae 12-18, Flos Woodfordiae Fruticosae 10-16, Radix Codonopsis 13-20, Radix Angelicae Dahuricae 9-15, Flos Magnoliae 10-17, Fructus Amomi Rotundus 9-14, Herba Andrographis 7-13, Flos Chrysanthemi 11-16, Herba Centipedae 10-14, Melanteritum 7-12, Radix Puerariae 9-13, Vicia unijuga 10-14, Folium Eriobotryae 9-14, Herba hyperici attenuati 11-15, Rhizoma Polygonati punctati 9-15, Herba Asari 8-16.
In preferred scheme, Ramulus Luffae 14-16, Flos Woodfordiae Fruticosae 12-14, Radix Codonopsis 15-18, Radix Angelicae Dahuricae 11-13, Flos Magnoliae 12-15, Fructus Amomi Rotundus 10-13, Herba Andrographis 9-11, Flos Chrysanthemi 13-14, Herba Centipedae 11-13, Melanteritum 8-11, Radix Puerariae 10-12, Vicia unijuga 11-13, Folium Eriobotryae 10-13, Herba hyperici attenuati 12-14, Rhizoma Polygonati punctati 10-14, Herba Asari 10-14.
Be more preferably, Ramulus Luffae 15, Flos Woodfordiae Fruticosae 13, Radix Codonopsis 16.5, the Radix Angelicae Dahuricae 12, Flos Magnoliae 13.5, Fructus Amomi Rotundus 11.5, Herba Andrographis 10, Flos Chrysanthemi 13.5, Herba Centipedae 12, Melanteritum 14.5, Radix Puerariae 11, Vicia unijuga 12, Folium Eriobotryae 11.5, Herba hyperici attenuati 13, Rhizoma Polygonati punctati 12, Herba Asari 12.
The Chinese medicine composition of described treatment rhinitis, be made into pharmaceutically acceptable powder, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) Melanteritum is broken into pieces, put into refractory container, with Sucus Zingberis, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, pulverized 120-200 mesh sieve and (preferably, pulverized 140-180 mesh sieve together with step (1) (3) made crude drug; Be more preferably, pulverized 160 mesh sieves), and mix with step (2) made powder, obtain powder.
The preparation method of the Chinese medicine powder of described treatment rhinitis, the amount of step (2) Sucus Zingberis is 0.2 times of Melanteritum quality.
The Chinese medicine composition of described treatment rhinitis, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Radix Puerariae and Rhizoma Polygonati punctati decontamination, infiltrate with clear water, take out, section, soak with the Herba Andrographis cleaned, Flos Chrysanthemi, Herba Centipedae, Vicia unijuga in non iron container together with Herba hyperici attenuati and step (1) (3) made crude drug, soak after 30 minutes, big fire is heated to boiling, then turn little fire decoct 20-30 minute (preferred, then turn little fire and decoct 22-28 minute; Be more preferably, then turn little fire and decoct 25 minutes), filter, collect filtrate, filtering residue adds water and again decocts, and filters, and merges twice and collects gained filtrate;
(5) step (2) made powder is added in step (4) made filtrate while hot, stir, obtain decoction.
The preparation method of the Chinese medicine composition decoction of described treatment rhinitis, doubly (preferred, the 7-8 that amount of water is boiled crude drug quality is doubly for the 6-9 that step (4) amount of water is boiled crude drug quality; Be more preferably, amount of water is 7.5 times of boiled crude drug quality).
The Chinese medicine composition of described treatment rhinitis, be made into pharmaceutically acceptable pill, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, pulverized 100-160 mesh sieve and (preferably, pulverized 120-140 mesh sieve together with step (1) (3) made crude drug; Be more preferably, pulverized 130 mesh sieves), and mix with step (2) made powder, obtained medicated powder, adds refined honey and water by made medicated powder, generally makes honeyed pill, obtains pill.
The preparation method of the Chinese medicine composition pill of described treatment rhinitis, step (4) made pill, heavy 0.3-0.5 gram of every ball (preferred, every ball weighs 0.4 gram).
The Chinese medicine composition of described treatment rhinitis, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Radix Puerariae and Rhizoma Polygonati punctati decontamination, infiltrate with clear water, take out, section, soak together with Herba hyperici attenuati and step (1) (3) made crude drug in non iron container (amount of water is 7.5 times of boiled crude drug quality) with the Herba Andrographis cleaned, Flos Chrysanthemi, Herba Centipedae, Vicia unijuga, soak after 30 minutes, big fire is heated to boiling, then turns little fire and decocts, and filters, collect filtrate, filtering residue is for subsequent use;
(5) step (4) remaining filtering residue is decocted with water twice, filter, collect twice gained filtrate, and merge with step (4) made filtrate, concentrate drying, mix with step (2) made powder, make medicated powder, then incapsulate, obtain capsule.
The preparation method of the Chinese medicinal composition capsules agent of described treatment rhinitis, step (4) turn little fire is decocted and (preferably, is then turned little fire and decoct 22-28 minute for 20-30 minute; Be more preferably, then turn little fire and decoct 25 minutes).
The Chinese medicine composition scientific formula for the treatment of rhinitis provided by the invention, preparation is simple, taking convenience.In addition, excellent results of the present invention also shows:
1, good effect of the present invention, cure rate is high, and anti-recurrence, all has significant curative effect to acute and chronic rhinitis;
2, this prescription meets Chinese medicine principle completely, has the effects such as clearing away heat to dispel wind, clearing the nasal passage, pain relieving;
3, the present invention is made up of Chinese medicine material, and products made thereby is safe and reliable, and untoward reaction is few, can long-term taking.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the Chinese medicine composition for the treatment of rhinitis, is prepared from (every part of 10g) primarily of following bulk drugs: Ramulus Luffae 12 parts, Flos Woodfordiae Fruticosae 10 parts, Radix Codonopsis 13 parts, the Radix Angelicae Dahuricae 9 parts, Flos Magnoliae 10 parts, Fructus Amomi Rotundus 9 parts, Herba Andrographis 7 parts, Flos Chrysanthemi 11 parts, Herba Centipedae 10 parts, Melanteritum 7 parts, Radix Puerariae 9 parts, Vicia unijuga 10 parts, Folium Eriobotryae 9 parts, Herba hyperici attenuati 11 parts, Rhizoma Polygonati punctati 9 parts, Herba Asari 8 parts.
The preparation method of the Chinese medicine powder for the treatment of rhinitis is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, 160 mesh sieves were pulverized together with step (1) (3) made crude drug, and mix with step (2) made powder, obtain powder.
embodiment 2the Chinese medicine composition for the treatment of rhinitis, is prepared from (every part of 10g) primarily of following bulk drugs: Ramulus Luffae 18 parts, Flos Woodfordiae Fruticosae 16 parts, Radix Codonopsis 20 parts, the Radix Angelicae Dahuricae 15 parts, Flos Magnoliae 17 parts, Fructus Amomi Rotundus 14 parts, Herba Andrographis 13 parts, Flos Chrysanthemi 16 parts, Herba Centipedae 14 parts, Melanteritum 12 parts, Radix Puerariae 13 parts, Vicia unijuga 14 parts, Folium Eriobotryae 14 parts, Herba hyperici attenuati 15 parts, Rhizoma Polygonati punctati 15 parts, Herba Asari 16 parts.
The preparation method of the Chinese medicine composition decoction for the treatment of rhinitis is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Radix Puerariae and Rhizoma Polygonati punctati decontamination, infiltrate with clear water, take out, section, soak together with Herba hyperici attenuati and step (1) (3) made crude drug in non iron container (amount of water is 7.5 times of boiled crude drug quality) with the Herba Andrographis cleaned, Flos Chrysanthemi, Herba Centipedae, Vicia unijuga, soak after 30 minutes, big fire is heated to boiling, then turn little fire and decoct 25 minutes, filter, collect filtrate, filtering residue adds water and again decocts, filter, merge twice and collect gained filtrate;
(5) step (2) made powder is added in step (4) made filtrate while hot, stir, obtain decoction.
Model case: xxx, female, 36 years old.Main suit: before two days, catches a cold because having a bath, and occurs nasal obstruction, watery nasal discharge, hypopnea, rear appearance heating fear of cold, headache, companion's sneeze, examination in hospital, body temperature 38.7 DEG C, the congested swelling of conchoscope Nasal mucosa, concha nasalis enlargement, has purulent secretion in nasal meatus, and leukocyte count increases, and is diagnosed as acute rhinitis.
Take the Chinese medicine composition decoction of the present embodiment gained treatment rhinitis, every day 2 times (warm), each 200-300ml, 20 days courses for the treatment of.After taking one day, body temperature is down to normally, headache relief, and after taking 3 days, nasal obstruction and watery nasal discharge obviously alleviate, breathe smooth and easy, after taking two weeks, patient, without malaise symptoms, breathes normal, inspection nasal cavity is without exception, and nasal mucosa and concha nasalis recover normal, and patient fully recovers, and follows up a case by regular visits to and do not recur in 1 year.
embodiment 3the Chinese medicine composition for the treatment of rhinitis, is prepared from (every part of 10g) primarily of following bulk drugs: Ramulus Luffae 14 parts, Flos Woodfordiae Fruticosae 12 parts, Radix Codonopsis 15 parts, the Radix Angelicae Dahuricae 11 parts, Flos Magnoliae 12 parts, Fructus Amomi Rotundus 10 parts, Herba Andrographis 9 parts, Flos Chrysanthemi 13 parts, Herba Centipedae 11 parts, Melanteritum 8 parts, Radix Puerariae 10 parts, Vicia unijuga 11 parts, Folium Eriobotryae 10 parts, Herba hyperici attenuati 12 parts, Rhizoma Polygonati punctati 10 parts, Herba Asari 10 parts.
The preparation method of the Chinese medicine composition pill for the treatment of rhinitis is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, 130 mesh sieves were pulverized together with step (1) (3) made crude drug, and mix with step (2) made powder, obtained medicated powder, adds refined honey and water by made medicated powder, the general honeyed pill making heavy 0.4 gram, obtains pill.
Model case: xxx, man, 16 years old.In this year, often feel headache, nasal obstruction, hyposmia, meet cold rear exacerbation of symptoms, pus tears increase, attend class absent minded, once take antibiotic medicine treatment, poor effect, within the next few days because of flu, nasal obstruction, headache aggravation, unbearably, examination in hospital, conchoscope checks the congested swelling of concha nasalis mucosa, and color is red, have purulent secretion in nasal meatus, X-ray film checks that two maxillary sinus is closely knit, is diagnosed as chronic rhinitis.
Take the Chinese medicine composition pill of the present embodiment gained treatment rhinitis, adopt every day 2 times, each 3-5 ball, with warm water delivery service, 20 days courses for the treatment of.After taking one week, nasal obstruction and headache obviously alleviate, and after taking a course for the treatment of, patient, without malaise symptoms, breathes smooth and easy, no headache, and olfactory sensation recovers normal, visual cognitive ability of attending class, and patient fully recovers, and follows up a case by regular visits to and do not recur in 1 year.
embodiment 4the Chinese medicine composition for the treatment of rhinitis, is prepared from (every part of 10g) primarily of following bulk drugs: Ramulus Luffae 16 parts, Flos Woodfordiae Fruticosae 14 parts, Radix Codonopsis 18 parts, the Radix Angelicae Dahuricae 13 parts, Flos Magnoliae 15 parts, Fructus Amomi Rotundus 13 parts, Herba Andrographis 11 parts, Flos Chrysanthemi 14 parts, Herba Centipedae 13 parts, Melanteritum 11 parts, Radix Puerariae 12 parts, Vicia unijuga 13 parts, Folium Eriobotryae 13 parts, Herba hyperici attenuati 14 parts, Rhizoma Polygonati punctati 14 parts, Herba Asari 14 parts.
The preparation method of the Chinese medicinal composition capsules agent for the treatment of rhinitis is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Radix Puerariae and Rhizoma Polygonati punctati decontamination, infiltrate with clear water, take out, section, soak together with Herba hyperici attenuati and step (1) (3) made crude drug in non iron container (amount of water is 7.5 times of boiled crude drug quality) with the Herba Andrographis cleaned, Flos Chrysanthemi, Herba Centipedae, Vicia unijuga, soak after 30 minutes, big fire is heated to boiling, then turns little fire and decocts 25 minutes, filters, collect filtrate, filtering residue is for subsequent use;
(5) step (4) remaining filtering residue is decocted with water twice, filter, collect twice gained filtrate, and merge with step (4) made filtrate, concentrate drying, mix with step (2) made powder, make medicated powder, then incapsulate, obtain capsule.
Model case: xxx, man, 60 years old.Medical history: have a stuffy nose 6 years, especially to attach most importance to night, with a small amount of white thick tears, resistance is poor, easy catching a cold, wind of recently catching a cold, nasal obstruction increases the weight of, and appetite declines, and sleep quality declines, examination in hospital, the congested swelling of concha nasalis inferior mucosa, in Polypoid changes, light red tongue, tongue is white, and stringy pulse, is diagnosed as chronic rhinitis.
Take the Chinese medicinal composition capsules agent of the present embodiment gained treatment rhinitis, adopt every day 2 times, each 3-4 grain, with warm water delivery service, 20 days courses for the treatment of.After taking one week, nasal obstruction alleviates, and appetite increases, after taking a course for the treatment of, nasal obstruction is basic to be alleviated, and occasional is had a stuffy nose, and continues to take a course for the treatment of, and patient's nasal obstruction disappears completely, appetite is normal, and immunity strengthens, and times of common cold comparatively treats front minimizing, follows up a case by regular visits to and do not recur in 1 year.
embodiment 5the Chinese medicine composition for the treatment of rhinitis, is prepared from (every part of 10g) primarily of following bulk drugs: Ramulus Luffae 15 parts, Flos Woodfordiae Fruticosae 13 parts, Radix Codonopsis 16.5 parts, the Radix Angelicae Dahuricae 12 parts, Flos Magnoliae 13.5 parts, Fructus Amomi Rotundus 11.5 parts, Herba Andrographis 10 parts, Flos Chrysanthemi 13.5 parts, Herba Centipedae 12 parts, Melanteritum 14.5 parts, Radix Puerariae 11 parts, Vicia unijuga 12 parts, Folium Eriobotryae 11.5 parts, Herba hyperici attenuati 13 parts, Rhizoma Polygonati punctati 12 parts, Herba Asari 12 parts.
The preparation method of the Chinese medicine powder for the treatment of rhinitis is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, 160 mesh sieves were pulverized together with step (1) (3) made crude drug, and mix with step (2) made powder, obtain powder.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Ramulus Luffae: base is former: be the stem of cucurbitaceous plant Fructus Luffae or Guangdong Fructus Luffae.Nature and flavor: bitter, are slightly cold, mild toxicity.Gui Jing: enter the heart, spleen, kidney channel.Function cures mainly: relaxing muscles and tendons, invigorates blood circulation, spleen invigorating, parasite killing.Control waist knee joint numb limbs and tense tendons, menoxenia, edema; Tooth reveals, nasal sinusitis, gingival atrophy.
Flos Woodfordiae Fruticosae: base is former: be root, the flower of Lythraceae plant Flos Woodfordiae Fruticosae.Nature and flavor: taste is micro-sweet, puckery, warm in nature.Function cures mainly: grate hemostasis of living, relaxing muscles and tendons and activating QI and blood in the collateral.Main dysmenorrhea, amenorrhea, metrorrhagia, epistaxis, hemoptysis, discharging fresh blood stool, dysentery, rheumatic arthralgia, lumbar muscle strain, traumatic injury.
Radix Codonopsis: base is former: be the root of Campanulaceae Radix Codonopsis.Nature and flavor: sweet are flat.Gui Jing: return spleen, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
The Radix Angelicae Dahuricae: base is former: be the root of samphire Angelica dahurica, angelica anomala, Radix angelicae dahuricae or Yunnan cattle Radix Saposhnikoviae.Nature and flavor: pungent, temperature.Gui Jing: return stomach, large intestine, lung meridian.Function cures mainly: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Flos Magnoliae: base is former: be the alabastrum of Magnoliacea plant Flos Magnoliae or Magnolia denudata.Nature and flavor: pungent, temperature.Gui Jing: attach to the lung and stomach meridians.Function cures mainly: dispersing wind and cold, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.
Fructus Amomi Rotundus: base is former: be the fruit of zingiberaceous plant Fructus Amomi Rotundus.Nature and flavor: pungent, temperature.Gui Jing: enter lung, spleen channel.Function cures mainly: circulation of qi promoting, and warming the stomach helps digestion, alleviating distention in middle-JIAO.Control the stagnation of QI, dyspepsia, uncomfortable in chest, abdominal distention, eructation, dysphagic, tell inverse, regurgitation, malaria.
Herba Andrographis: base is former: be herb or the leaf of acanthaceous plant Herba Andrographis.Nature and flavor: bitter, cold.Gui Jing: GUIXIN, lung, large intestine, urinary bladder channel.Function cures mainly: heat-clearing and toxic substances removing, removing heat from blood, detumescence.For cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
Flos Chrysanthemi: base is former: be the head inflorescence of feverfew chrysanthemum.Nature and flavor: sweet, bitter, are slightly cold.Gui Jing: return lung, Liver Channel.Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.
Herba Centipedae: base is former: be the wounded in the battle herb of feverfew Myriogyne minuta.Nature and flavor: pungent, temperature.Gui Jing: return lung, Liver Channel.Function cures mainly: clearing the nasal passage, cough-relieving, and for headche due to wind-cold, cough with copious phlegm, has a stuffy nose obstructed, nasal sinusitis watery nasal discharge.
Melanteritum: base is former: be Ore or the synthetic of Sulfates fossil water Melanteritum.Nature and flavor: sour, puckery, cool.Gui Jing: enter spleen, liver.Function cures mainly: drying dampness to eliminate phlegm, eliminating stagnated food and killing intestinal worms, and hemostasis is enriched blood, removing toxic substances sore.Swelling of harnessing the Yellow River is full, infantile malnutrition chronic dysentery, discharging fresh blood stool, blood deficiency and yellow complexion, eczema scabies, sore throat aphtha, marginal blepharitis eye.
Radix Puerariae: base is former: be the tuber of leguminous plant Pueraria lobota.Nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Vicia unijuga: base is former: be the herb of pulse family Vetch plant Vicia unijuga and short sequence Vicia unijuga.Nature and flavor: sweet are flat.Function cures mainly: tonify deficiency, adjusts liver, regulating QI to relieve pain, clearing away heat and promoting diuresis.Cure mainly asthenia, dizzy, headache, edema, stomachache, furuncle furuncle is controlled in external.
Folium Eriobotryae: base is former: be the blade of rosaceous plant Folium Eriobotryae, nature and flavor: bitter, are slightly cold.Gui Jing: attach to the lung and stomach meridians.Function cures mainly: clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.
Herba hyperici attenuati: base is former: be the herb of Guttiferae spun gold platymiscium Herba hyperici attenuati.Nature and flavor: bitter, flat.Function cures mainly: cooling blood for hemostasis, invigorates blood circulation, detumescence.Cure mainly haematemesis, spitting of blood, metrorrhagia, traumatic hemorrhage, rheumatic arthralgia, traumatic injury, carbuncle furuncle, acute mastitis swells and ache, agalactia, scalds and snake bite and insect sting.
Rhizoma Polygonati punctati: base is former: be the rhizome of Bulbus Lilii kind of plant Rhizoma Polygonati punctati.Nature and flavor: sweet are bitter, flat.Gui Jing: spleen channel.Function cures mainly: spleen reinforcing benefit blood, removing toxicity for eliminating carbuncles.Main insufficiency of the spleen insufficiency of blood, dizzy few food, fatigue and weakness, swollen ulcer drug.
Herba Asari: base is former: be the whole herb with root of aristolochiaceae plant Herba Asari or magnificent Herba Asari.Nature and flavor: pungent, temperature.Gui Jing: GUIXIN, lung, kidney channel.Function cures mainly: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
test example 1the clinical practice of the Chinese medicine composition (embodiment 5) of gained treatment rhinitis of the present invention:
In June, 2013, in December ,-2014, filtered out 317 examples as object of study the patients with rhinitis of four hospitals treatment, wherein women 148 example, male 169 example, age 10-62 year, 37.4 ± 2.6 years old mean age, the course of disease 7 days-6 years.Diagnostic criteria: Western medicine diagnose standard is with reference to " ENT & HN Surgery Dept. ".Tcm diagnosis standard is with reference to " Chinese medical disease Standardization of diagnosis and curative effect ".
Patient is divided into two groups at random, experimental group 162 example and matched group 155 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (
p> 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, and every day takes twice, and each 5-8g(adjusts to some extent depending on concrete condition), 20 days courses for the treatment of, matched group takes other medicine as conventional medication such as rhinitis tablet, Biyan Ning granule, nasal sinusitis sheets.Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: cure: nasal obstruction, headache and the clinical symptoms such as rhinorrhea and sign disappear, nose body surface area without tenderness, the inspections such as via intranasal application mirror, X-ray film, CT, the disappearances such as nasal conchae hypertrophy, nasal decongestion swelling, inflammatory, hydrops; Effective: clinical symptoms and sign disappear substantially, occasionally have the symptom such as watery nasal discharge, nasal obstruction, headache, nasal conchae hypertrophy, inflammatory etc. obviously improve, and nasal mucosa mild hyperaemia, without purulent secretion; Invalid: before and after treatment, clinical symptoms and sign are without significant change.
Table 1 liang group comparitive study
As shown in Table 1: through the treatment of a course for the treatment of, experimental group patient cures 102 examples, effective 56 examples, invalid 4 examples, treatment total effective rate is 97.5%, and matched group cures 51 examples, effective 78 examples, invalid 26 examples, treatment total effective rate be that 83.2%, two groups of total effective rates compare, exist significant difference (
p< 0.05), experimental group curative effect is better than matched group.Follow up a case by regular visits to after half a year, experimental group is without Patients on Recurrence, and matched group has 18 routine Patients on Recurrences.All there is not any untoward reaction in treatments period two groups of patients.
Ramulus Luffae relaxing muscles and tendons to promote blood circulation in formula of the present invention, Flos Woodfordiae Fruticosae grate hemostasis alive, Radix Codonopsis invigorating the spleen and replenishing QI, Radix Angelicae Dahuricae understand things pain-stopping, Flos Magnoliae and Herba Centipedae clearing the nasal passage, Fructus Amomi Rotundus promoting the circulation of QI to alleviate the stagnation in middle-JIAO, Herba Andrographis heat-clearing and toxic substances removing, the heat clearing away of chrysanthemum powder forimproving wind, Melanteritum drying dampness to eliminate phlegm, Radix Puerariae expelling pathogenic factors from muscles for reducing heat, Vicia unijuga tonify deficiency adjusts liver, Folium Eriobotryae clearing away lung-heat to relieve cough, Herba hyperici attenuati removing heat from blood and promoting blood circulation, Rhizoma Polygonati punctati removing toxicity for eliminating carbuncles, Herba Asari expelling wind and cold, all medicines use together, can play the effects such as clearing away heat to dispel wind, clearing the nasal passage, pain relieving, all have significant curative effect to acute and chronic nasopharynx.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the Chinese medicine composition of rhinitis, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Ramulus Luffae 12-18, Flos Woodfordiae Fruticosae 10-16, Radix Codonopsis 13-20, Radix Angelicae Dahuricae 9-15, Flos Magnoliae 10-17, Fructus Amomi Rotundus 9-14, Herba Andrographis 7-13, Flos Chrysanthemi 11-16, Herba Centipedae 10-14, Melanteritum 7-12, Radix Puerariae 9-13, Vicia unijuga 10-14, Folium Eriobotryae 9-14, Herba hyperici attenuati 11-15, Rhizoma Polygonati punctati 9-15, Herba Asari 8-16.
2. the Chinese medicine composition for the treatment of rhinitis as claimed in claim 1, it is characterized in that, Ramulus Luffae 14-16, Flos Woodfordiae Fruticosae 12-14, Radix Codonopsis 15-18, Radix Angelicae Dahuricae 11-13, Flos Magnoliae 12-15, Fructus Amomi Rotundus 10-13, Herba Andrographis 9-11, Flos Chrysanthemi 13-14, Herba Centipedae 11-13, Melanteritum 8-11, Radix Puerariae 10-12, Vicia unijuga 11-13, Folium Eriobotryae 10-13, Herba hyperici attenuati 12-14, Rhizoma Polygonati punctati 10-14, Herba Asari 10-14 is (preferred, Ramulus Luffae 15, Flos Woodfordiae Fruticosae 13, Radix Codonopsis 16.5, the Radix Angelicae Dahuricae 12, Flos Magnoliae 13.5, Fructus Amomi Rotundus 11.5, Herba Andrographis 10, Flos Chrysanthemi 13.5, Herba Centipedae 12, Melanteritum 14.5, Radix Puerariae 11, Vicia unijuga 12, Folium Eriobotryae 11.5, Herba hyperici attenuati 13, Rhizoma Polygonati punctati 12, Herba Asari 12).
3. the Chinese medicine composition of the treatment rhinitis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) Melanteritum is broken into pieces, put into refractory container, with Sucus Zingberis, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, pulverized 120-200 mesh sieve and (preferably, pulverized 140-180 mesh sieve together with step (1) (3) made crude drug; Be more preferably, pulverized 160 mesh sieves), and mix with step (2) made powder, obtain powder.
4. the preparation method of the Chinese medicine powder for the treatment of rhinitis as claimed in claim 3, it is characterized in that, the amount of step (2) Sucus Zingberis is 0.2 times of Melanteritum quality.
5. the Chinese medicine composition of the treatment rhinitis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Radix Puerariae and Rhizoma Polygonati punctati decontamination, infiltrate with clear water, take out, section, soak with the Herba Andrographis cleaned, Flos Chrysanthemi, Herba Centipedae, Vicia unijuga in non iron container together with Herba hyperici attenuati and step (1) (3) made crude drug, soak after 30 minutes, big fire is heated to boiling, then turn little fire decoct 20-30 minute (preferred, then turn little fire and decoct 22-28 minute; Be more preferably, then turn little fire and decoct 25 minutes), filter, collect filtrate, filtering residue adds water and again decocts, and filters, and merges twice and collects gained filtrate;
(5) step (2) made powder is added in step (4) made filtrate while hot, stir, obtain decoction.
6. the preparation method of the Chinese medicine composition decoction for the treatment of rhinitis as claimed in claim 5, is characterized in that, doubly (preferred, the 7-8 that amount of water is boiled crude drug quality doubly for the 6-9 that step (4) amount of water is boiled crude drug quality; Be more preferably, amount of water is 7.5 times of boiled crude drug quality).
7. the Chinese medicine composition of the treatment rhinitis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Andrographis, Flos Chrysanthemi, Herba Centipedae, Radix Puerariae, Vicia unijuga, Herba hyperici attenuati and Rhizoma Polygonati punctati decontamination, wash quickly is clean, dry, pulverized 100-160 mesh sieve and (preferably, pulverized 120-140 mesh sieve together with step (1) (3) made crude drug; Be more preferably, pulverized 130 mesh sieves), and mix with step (2) made powder, obtained medicated powder, adds refined honey and water by made medicated powder, generally makes honeyed pill, obtains pill.
8. the preparation method of the Chinese medicine composition pill for the treatment of rhinitis as claimed in claim 7, is characterized in that, step (4) made pill, heavy 0.3-0.5 gram of every ball (preferred, every ball weighs 0.4 gram).
9. the Chinese medicine composition of the treatment rhinitis as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) Flos Magnoliae, Fructus Amomi Rotundus and Herba Asari are picked clean impurity, wash quickly is clean, uses Musa basjoo Sieb. Et Zucc. water saturates, and take out, slow fire dries;
(2) broken into pieces by Melanteritum, put into refractory container, add the Sucus Zingberis of Melanteritum quality 0.2 times, covered and enclosed, intense fire is heated to Melanteritum and dissolves, and stirs with Folium Bambusae, continues to be calcined to Sucus Zingberis to the greatest extent, is all degree in deep red color, takes out, cool, pulverize;
(3) get Folium Eriobotryae glycyrrhiza decoction to infiltrate, wipe the hair on surface away, then clean up with glycyrrhiza decoction, dry, refined honey water is coated on Folium Eriobotryae surface uniformly, and low baking temperature dries;
(4) by Ramulus Luffae, Flos Woodfordiae Fruticosae, Radix Codonopsis, the Radix Angelicae Dahuricae, Radix Puerariae and Rhizoma Polygonati punctati decontamination, infiltrate with clear water, take out, section, soak together with Herba hyperici attenuati and step (1) (3) made crude drug in non iron container (amount of water is 7.5 times of boiled crude drug quality) with the Herba Andrographis cleaned, Flos Chrysanthemi, Herba Centipedae, Vicia unijuga, soak after 30 minutes, big fire is heated to boiling, then turns little fire and decocts, and filters, collect filtrate, filtering residue is for subsequent use;
(5) step (4) remaining filtering residue is decocted with water twice, filter, collect twice gained filtrate, and merge with step (4) made filtrate, concentrate drying, mix with step (2) made powder, make medicated powder, then incapsulate, obtain capsule.
10. the preparation method of the Chinese medicinal composition capsules agent for the treatment of rhinitis as claimed in claim 9, is characterized in that, step (4) turn little fire is decocted and (preferably, then turned little fire and decoct 22-28 minute for 20-30 minute; Be more preferably, then turn little fire and decoct 25 minutes).
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| CN112870256A (en) * | 2021-03-11 | 2021-06-01 | 海南善济堂中医研究院有限公司 | Traditional Chinese medicine composition for treating rhinitis |
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