CN104799823A - Temperature sensation stimulation device - Google Patents

Temperature sensation stimulation device Download PDF

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Publication number
CN104799823A
CN104799823A CN201510204523.2A CN201510204523A CN104799823A CN 104799823 A CN104799823 A CN 104799823A CN 201510204523 A CN201510204523 A CN 201510204523A CN 104799823 A CN104799823 A CN 104799823A
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CN
China
Prior art keywords
temperature
stimulation
thermo aesthesia
module
control module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510204523.2A
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Chinese (zh)
Inventor
董涛
梁思
王慧
杨晓冬
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Suzhou Institute of Biomedical Engineering and Technology of CAS
Original Assignee
Suzhou Institute of Biomedical Engineering and Technology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Suzhou Institute of Biomedical Engineering and Technology of CAS filed Critical Suzhou Institute of Biomedical Engineering and Technology of CAS
Priority to CN201510204523.2A priority Critical patent/CN104799823A/en
Publication of CN104799823A publication Critical patent/CN104799823A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4005Detecting, measuring or recording for evaluating the nervous system for evaluating the sensory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging

Abstract

The invention discloses a temperature sensation stimulation device. The temperature sensation stimulation device comprises a stimulation control unit, a data acquisition card, a digital signal processing module, a temperature control module and a temperature sensation stimulation terminal, wherein the stimulation control unit is used for setting a needed temperature stimulation sequence; the data acquisition card is used for converting the temperature stimulation sequence from a decimal form to a binary temperature value and transmitting the temperature value to the digital signal processing module; the digital signal processing module is used for receiving the binary temperature value and converting the binary temperature value to a stimulation sensation value and transmitting the stimulation sensation value to the temperature control module; the temperature control module is used for controlling the current on the temperature sensation stimulation end according to the stimulation temperature value; the temperature sensation stimulation terminal is used for outputting the corresponding temperature to a tester according to the current outputted by a human body stimulated part. The temperature sensation stimulation device is simple in structure and convenient to use; when in use, the human body stimulated part is tightly fit to the stimulation terminal, the current of the temperature stimulation terminal is adjusted by virtue the temperature control module, and the temperature of the stimulation terminal can be rapidly and stably controlled.

Description

Thermo aesthesia stimulating apparatus
Technical field
The present invention relates to a kind of photoreceptor apoptosis device, be specifically related to a kind of thermo aesthesia stimulating apparatus.
Background technology
When being subject to special environmental stimuli, brain will produce a response encouraged by the external world, the power of this response can characterize by scalp or cortex being measured the voltage signal obtained, or reflected by brain magnetic signal, the result also by Positron emission computed tomography (PET) or functional mri (fMRI) embodies.Wherein stimulating by giving tested thermo aesthesia, the thermo aesthesia nervous pathway relevant issues of brain can be studied.
The response that brain stimulates for thermo aesthesia, mainly by giving different stimulation temperature signals, is mainly divided into two classes.One class is the cold stimulation lower than tested skin temperature; One class is the thermostimulation higher than tested skin temperature.
By the research responded these, the activity of brain on treatment temperature visual information can be disclosed.And the development of above-mentioned research, need to be based upon on the basis of thermo aesthesia stimulating apparatus.At present, the blank stage is also in for the thermo aesthesia stimulating apparatus of thermo aesthesia research at home.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of can formation temperature feel stimulate thermo aesthesia stimulating apparatus.
In order to achieve the above object, technical scheme of the present invention is as follows:
Thermo aesthesia stimulating apparatus, it comprises:
Stimulate control unit, for setting the thermal stimulus sequence needing to reach;
Data collecting card, for changing thermal stimulus sequence the binary system temperature value of binary form into by decimal form and being sent to digital signal processing module;
Digital signal processing module, for receiving binary system temperature value and being converted into stimulation temperature value, and is sent to temperature control module by this stimulation temperature value;
Temperature control module, for carrying out the size of current of control temperature feel stimulated side according to stimulation temperature value;
Thermo aesthesia stimulated side, exports corresponding temperature for the electric current exported according to temperature control module to tester.
The present invention is by stimulating the temperature value reached required for control unit setting, by data collecting card, this temperature value is converted to the signal that can be able to be identified by digital signal processing module, digital signal processing module goes according to this signal the size of current controlling temperature control module again, thermo aesthesia stimulated side exports corresponding temperature according to the input quantity of electric current to tester again, the object that formation temperature feel stimulates.
Compared with prior art, its structure is simple and easy to use in the present invention, only needs human body stimulation location to be close to stimulated side during use, regulates the size of current passed through of stimulated side by temperature control module, can the temperature of regulation and control stimulated side of fast and stable.
On the basis of technique scheme, the present invention can also do following improvement:
As preferred scheme, above-mentioned thermo aesthesia stimulating apparatus, it also comprises temperature sensor, it is arranged on thermo aesthesia stimulated side, real time temperature on temperature sensor feel stimulated side, and by the real time temperature collected to being sent to temperature control module, the temperature value of real-time temperature values and setting compares by this temperature control module, the output temperature of adjustment thermo aesthesia stimulated side in real time.
As preferred scheme, above-mentioned thermo aesthesia stimulating apparatus also comprises communication module, for detecting the pulse signal of the setpoint frequency of magnetic resonance device, sends for the control instruction that starts to digital signal processing module according to this pulse signal.
Adopt above-mentioned preferred scheme, this thermo aesthesia stimulating apparatus can be made to be formed with detection magnetic resonance device and link, only when detecting magnetic resonance device and starting, this thermo aesthesia stimulating apparatus just can start, to prevent the maloperation to thermo aesthesia stimulating apparatus.
As preferred scheme, above-mentioned thermo aesthesia stimulating apparatus also comprises display module, and it connects digital signal processing module, for the real time temperature that display digit signal processing module receives.
Adopt above-mentioned preferred scheme, can carry out real-time display to the change of temperature value in thermo aesthesia stimulating apparatus, person easy to use checks.
As preferred scheme, above-mentioned stimulation control unit comprises:
Stimulus sequence design module, for providing the visualization interface for temperature value setting, and for user's set temperature value and stimulation time to user;
Stimulus sequence execution module, for the temperature value of control data capture card transmission setting.
Adopt above-mentioned preferred scheme, user can be formed this thermo aesthesia stimulating apparatus more intuitively, is efficiently controlled.
As preferred scheme, above-mentioned stimulus sequence design module also for setting temperature duration parameter, realizes the control of the working time to thermo aesthesia stimulated side.
Adopt above-mentioned preferred scheme, the control for output temperature can be made more accurate.
As preferred scheme, above-mentioned temperature control module also control temperature feels the sense of current of stimulated side, for changing the cold and hot temperature value of thermo aesthesia stimulated side.
Adopt above-mentioned preferred scheme, by the control to the sense of current, the output of temperature can be made more accurate.
As preferred scheme, above-mentioned temperature control module is digital PID temperature control module, for feeling the current value of stimulated side by stimulating temperature value to change into for control temperature by pid algorithm.
Adopt above-mentioned preferred scheme, can so that the signal with temperature value to be changed into the signal with current value.
As preferred scheme, above-mentioned thermo aesthesia stimulated side comprises semiconductor chilling plate, exports corresponding temperature for the electric current exported according to temperature control module to tester.
Adopt above-mentioned preferred scheme, can so that export corresponding temperature according to size of current.
As preferred scheme, above-mentioned thermo aesthesia stimulated side also comprises: heat barrier foam, and it is arranged at the surrounding of described semiconductor chilling plate, and user can be avoided to touch fin; Fin, it is arranged at the below of described heat barrier foam.Adopt above-mentioned preferred scheme, the thermolysis to semiconductor chilling plate can be formed.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of thermo aesthesia stimulating apparatus of the present invention.
Fig. 2 is the structure chart of thermo aesthesia stimulated side involved in thermo aesthesia stimulating apparatus of the present invention.
Fig. 3 is the implementing procedure figure of thermo aesthesia stimulating apparatus of the present invention.
Wherein, 1.PC machine 2. data collecting card 3. digital signal processing module 4. temperature control module 5. thermo aesthesia stimulated side 501. fin 502. heat barrier foam 503. semiconductor chilling plate 504. temperature sensor 6. power module 7. communication module 8. display module.
Detailed description of the invention
The preferred embodiment of the present invention is described in detail below in conjunction with accompanying drawing.
In order to reach object of the present invention, as Figure 1-3, in the some of them embodiment of thermo aesthesia stimulating apparatus of the present invention, it comprises: power module 6, for providing the voltage (such as DC voltage) of multiple amplitude, stimulate control unit, it is located in PC 1, being write in PC 1 by experimenter stimulates software to be formed, LabVIEW software platform specifically can be adopted to write stimulation software, realize User Defined stimulus sequence, this stimulation control unit is for setting the thermal stimulus sequence needing to reach, this stimulation control unit specifically can comprise stimulus sequence design module and stimulus sequence execution module, stimulus sequence design module is used for providing to user the visualization interface set for thermal stimulus sequence, comprise user's design temperature stimulus sequence and temperature duration parameter, stimulus sequence execution module is used for the thermal stimulus sequence of control data capture card transmission setting, stimulus sequence design module also can be used for setting temperature duration parameter, realize the control to the working time of thermo aesthesia stimulated side, the interface of stimulus sequence execution module can show " always testing progress " and " this tests progress " two kinds of different conditions simultaneously, this software output packet on PC contains the log file stimulating temperature and stimulation time point, for realizing the synchronous of thermal stimulus and image acquisition, after wherein " stimulus sequence execution " refers to the instruction that user sends " starting to stimulate ", software control data capture card transmits different thermal stimulus sequences according to the stimulus sequence designed, control stimulated side and realize different thermal stimuluss, data collecting card 2, its National Instruments that can adopt (National Instruments, NI) data acquisition equipment, can be used for receiving the stimulus sequence stimulating software design, for changing thermal stimulus sequence the binary system temperature value of binary form into by decimal form and being sent to digital signal processing module 3, digital signal processing module 3, it can be microcontrol processor, can comprise single-chip microcomputer, FPGA or PLC, and this stimulation temperature value for receiving binary system temperature value and being converted into stimulation temperature value, and is sent to temperature control module 4 by this digital signal processing module 3, temperature control module 4, it can adopt the temperature control module that PID temperature control module etc. is known, this temperature control module 4 is for carrying out the size of current of control temperature feel stimulated side 5 according to stimulation temperature value, the sense of current of all right control temperature feel stimulated side 5 further, for changing the cold and hot temperature value of thermo aesthesia stimulated side 5, to improve control accuracy, thermo aesthesia stimulated side 5, electric current for exporting according to temperature control module 4 exports corresponding temperature to tester, this thermo aesthesia stimulated side 5 can comprise semiconductor chilling plate 503, the form of semiconductor chilling plate 503 is utilized to carry out output temperature, this thermo aesthesia stimulated side 5 can also add fin 501 and heat barrier foam 502 on the basis of semiconductor chilling plate 503, heat barrier foam 502 is arranged at the surrounding of semiconductor chilling plate 503, user can be avoided to touch fin 501, fin 501 its be arranged at the below of heat barrier foam 502, to form thermolysis.
This device is by stimulating the temperature value reached required for control unit setting, by data collecting card, this temperature value is converted to the signal that can be able to be identified by digital signal processing module, digital signal processing module goes according to this signal the size of current controlling temperature control module again, thermo aesthesia stimulated side exports corresponding temperature according to the input quantity of electric current to tester again, the object that formation temperature feel stimulates.Compared with prior art, its structure is simple and easy to use for this device, only needs human body stimulation location to be close to stimulated side during use, regulates the size of current passed through of stimulated side by temperature control module, can the temperature of regulation and control stimulated side of fast and stable.Meanwhile, display screen is all separated with stimulated side with the equipment such as gauge tap, power supply of circuit by this device, can be user operation so in particular circumstances and provides great convenience.
In order to optimize implementation result of the present invention further, as illustrated in fig. 1 and 2, in other embodiments of thermo aesthesia stimulating apparatus of the present invention, on the basis of the above, it also comprises temperature sensor 504, it is arranged on thermo aesthesia stimulated side 5, for the real time temperature on temperature sensor feel stimulated side 5, and by the real time temperature collected to being sent to temperature control module 4, real-time temperature values is sent to stimulation control unit by temperature control module 4 again, the temperature value of real-time temperature values and setting compares by this stimulation control unit, then by data collecting card 2, digital signal processing module 3 and temperature control module 4 adjust the output temperature of thermo aesthesia stimulated side 5 in real time, concrete handling process is the same with above-mentioned embodiment, again repeat no more, corresponding size of current is controlled according to variations in temperature, temperature is high reduction electric current or stop output current, temperature is low high current or continue output current.Adopt the scheme of this embodiment, temperature sensor can real time temperature on Real-time Collection thermo aesthesia stimulated side, then this real-time temperature values is fed back by temperature control module to stimulation control unit, control unit is stimulated to determine that improving temperature the need of control still reduces temperature, reaches the temperature value of initial setting according to this real-time temperature values again.
In order to optimize implementation result of the present invention further, as shown in figs. 1 and 3, in other embodiments of thermo aesthesia stimulating apparatus of the present invention, on the basis of the above, above-mentioned thermo aesthesia stimulating apparatus also comprises communication module 7, and it can adopt bluetooth module, for detecting the pulse signal of the setpoint frequency of magnetic resonance device, the i.e. pulse signal of characteristic frequency, sends for the control instruction (i.e. triggering command) that starts to digital signal processing module according to this pulse signal.Adopt the scheme of this embodiment, this thermo aesthesia stimulating apparatus can be made to be formed with detection magnetic resonance device and link, only when detecting magnetic resonance device and starting, this thermo aesthesia stimulating apparatus just can start, to prevent the maloperation to thermo aesthesia stimulating apparatus.
In order to optimize implementation result of the present invention further, as shown in figs. 1 and 3, in other embodiments of thermo aesthesia stimulating apparatus of the present invention, on the basis of the above, above-mentioned thermo aesthesia stimulating apparatus also comprises display module 8, and it can adopt LCD display, and it connects digital signal processing module 3, for the real time temperature that display digit signal processing module 3 receives, comprise the real-time temperature values stimulating temperature value and thermo aesthesia stimulated side 5.Adopt the scheme of this embodiment, can carry out real-time display to the change of temperature value in thermo aesthesia stimulating apparatus, person easy to use checks.
The workflow of this thermo aesthesia stimulating apparatus is as follows:
When this thermo aesthesia stimulating apparatus is combined with fMRI, need the main part of this thermo aesthesia stimulating apparatus to be placed in operating room, thermo aesthesia stimulated side is placed in screened room, in order to ensure that stimulating apparatus meets fMRI environment for use.
In the experiment of fMRI thermo aesthesia, first allow testedly lying low in the main magnet bore of magnetic resonance device, right hand touching stimulated side.Testing fixture with or without wiring error, engaging means power supply.Experimenter writes the required stimulus sequence of experiment in PC stimulation software.Open magnetic resonance device, when communication module detects the pulse signal of magnetic resonance device characteristic frequency, open experimental provision.Stimulate running software, synchronously start to stimulate with magnetic resonance device.Stimulus sequence, by data collecting card, sends control instruction to digital signal processing module, and digital signal processing module is converted into stimulation temperature value to the control instruction process obtained, and by serial ports, the temperature value after process is passed to digital PID temperature control module.Digital PID temperature control module, by the temperature value of the stimulated side of monitor temperature sensor continuous acquisition, utilizes pid algorithm to control the sense of current and size in stimulated side in real time, reaches the object accurately controlling stimulated side temperature.Meanwhile, temperature value is passed to digital signal processing module by serial ports by digital PID temperature control module, and display module shows in real time.Whole process will repeatedly, until experiment terminates.In the middle of whole process, experimenter can be given corresponding feedback information by feedback device as tester runs into discomfort.
Above-described is only the preferred embodiment of the present invention, it should be pointed out that for the person of ordinary skill of the art, and without departing from the concept of the premise of the invention, can also make some distortion and improvement, these all belong to protection scope of the present invention.

Claims (10)

1. thermo aesthesia stimulating apparatus, is characterized in that, comprising:
Stimulate control unit, for setting the thermal stimulus sequence needing to reach;
Data collecting card, for changing described thermal stimulus sequence the binary system temperature value of binary form into by decimal form and being sent to digital signal processing module;
Digital signal processing module, for receiving described binary system temperature value and being converted into stimulation temperature value, and is sent to temperature control module by described stimulation temperature value;
Temperature control module, for carrying out the size of current of control temperature feel stimulated side according to described stimulation temperature value;
Thermo aesthesia stimulated side, exports corresponding temperature for the electric current exported according to described temperature control module to tester.
2. thermo aesthesia stimulating apparatus according to claim 1, it is characterized in that, also comprise temperature sensor, it is arranged on described thermo aesthesia stimulated side, for responding to the real time temperature on described thermo aesthesia stimulated side, and the real time temperature collected is sent to described temperature control module, described real-time temperature values and set temperature value compare by described temperature control module, in real time the output temperature of the described thermo aesthesia stimulated side of adjustment.
3. thermo aesthesia stimulating apparatus according to claim 1, it is characterized in that, also comprising communication module, for detecting the pulse signal of the setpoint frequency of magnetic resonance device, sending the control instruction extremely described digital signal processing module for starting according to described pulse signal.
4. thermo aesthesia stimulating apparatus according to claim 1, is characterized in that, also comprise display module, and it connects described digital signal processing module, for showing the real time temperature that described digital signal processing module receives.
5. thermo aesthesia stimulating apparatus according to claim 1, is characterized in that, described stimulation control unit comprises:
Stimulus sequence design module, for providing the visualization interface for temperature value setting, and for user's set temperature value and stimulation time to user;
Stimulus sequence execution module, for controlling the temperature value of described data collecting card transmission setting.
6. thermo aesthesia stimulating apparatus according to claim 5, is characterized in that, described stimulus sequence design module, also for setting temperature duration parameter, realizes the control of the working time to described thermo aesthesia stimulated side.
7. thermo aesthesia stimulating apparatus according to claim 1, is characterized in that, described temperature control module also controls the sense of current of described thermo aesthesia stimulated side, for changing the cold and hot temperature value of described thermo aesthesia stimulated side.
8. thermo aesthesia stimulating apparatus according to claim 1, is characterized in that, described temperature control module is digital PID temperature control module, for by pid algorithm described stimulation temperature value being changed into the current value for controlling described thermo aesthesia stimulated side.
9. thermo aesthesia stimulating apparatus according to claim 1, is characterized in that, described thermo aesthesia stimulated side comprises semiconductor chilling plate, exports corresponding temperature for the electric current exported according to described temperature control module to tester.
10. thermo aesthesia stimulating apparatus according to claim 9, is characterized in that, described thermo aesthesia stimulated side also comprises:
Heat barrier foam, it is arranged at the surrounding of described semiconductor chilling plate;
Fin, it is arranged at the below of described heat barrier foam.
CN201510204523.2A 2015-04-27 2015-04-27 Temperature sensation stimulation device Pending CN104799823A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1530787A (en) * 2003-03-16 2004-09-22 华为技术有限公司 Temperature controlling system
WO2013168168A1 (en) * 2012-05-09 2013-11-14 Medoc Ltd. Improved thermal stimulation probe and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1530787A (en) * 2003-03-16 2004-09-22 华为技术有限公司 Temperature controlling system
WO2013168168A1 (en) * 2012-05-09 2013-11-14 Medoc Ltd. Improved thermal stimulation probe and method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
王骁冠等: "一种用于fMRI的嗅觉刺激装置设计与验证", 《波谱学杂志》 *
董涛等: "一种用于fMRI的温度觉刺激装置设计与验证", 《波谱学杂志》 *

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Application publication date: 20150729

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