CN104799440B - Improve function clothes and the manufacture method thereof of metabolic syndrome - Google Patents
Improve function clothes and the manufacture method thereof of metabolic syndrome Download PDFInfo
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- CN104799440B CN104799440B CN201410033574.9A CN201410033574A CN104799440B CN 104799440 B CN104799440 B CN 104799440B CN 201410033574 A CN201410033574 A CN 201410033574A CN 104799440 B CN104799440 B CN 104799440B
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41B—SHIRTS; UNDERWEAR; BABY LINEN; HANDKERCHIEFS
- A41B9/00—Undergarments
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41B—SHIRTS; UNDERWEAR; BABY LINEN; HANDKERCHIEFS
- A41B9/00—Undergarments
- A41B9/12—Protective undergarments
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- A—HUMAN NECESSITIES
- A41—WEARING APPAREL
- A41B—SHIRTS; UNDERWEAR; BABY LINEN; HANDKERCHIEFS
- A41B2400/00—Functions or special features of shirts, underwear, baby linen or handkerchiefs not provided for in other groups of this subclass
- A41B2400/32—Therapeutic use
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Abstract
The present invention relates to a kind of function clothes improving metabolic syndrome, raw material for preparation function clothes: functional layer fabric and auxiliary functional layer fabric, the present invention have devised two kinds of auxiliary agents: the first auxiliary agent and the second auxiliary agent, first auxiliary agent makes the inner surface of functional layer fabric have hydrophilic, warming and airing function, and the second auxiliary agent makes to adhere to L-carnitine on the inner surface of auxiliary functional layer fabric. Enforcement the invention has the beneficial effects as follows: this function clothes are a kind of direct and contact skin clothing, its outer surface has good hydrophobic function, control by hydrophilic, the warming and fabulous airing function that its inner surface is good, utilize the warm and humid environment construction drug transdermal delivery system of skin surface, assist little molecular hydrophylic medicine L-carnitine Transdermal absorption, user wears this function clothes for a long time, can improve insulin and the secretion of fat correlation factor, and then improve metabolic syndrome. It is simple to operate that corresponding function provided by the invention takes manufacture method, with low cost.
Description
Technical field
The present invention relates to textile technology field, particularly relate to and a kind of directly contact with human body skin, the combination with specific function fabric prepare, long-term dress is conducive to the function improving body metabolism syndrome to take and manufacture method.
Background technology
A kind of syndrome being associated with hypertension and glucose and abnormalities of sugar/lipid metabolism is " metabolic syndrome (MetabolicSyndrome) " by World Health Organization (WHO). " metabolic syndrome " embodiment " four high one low ": namely hypertension, hyperglycemia, hyperinsulinemia, high triglyceride, low high-density protein. Along with bad dietetic lifes such as the raising of modern life level, long-term high purine diet, excessive drinkings, body weight is caused to increase or fat. Additionally, due to work overloadingly for a long time, body is in neural excitation state, causing increased heart rate, peripheral vessels shrinks, and blood pressure rises, add sitting office, physical exertion is few, consuming little energy, makes body surrounding tissue especially make muscular tissue that the utilization rate of sugar is gone down, therefore islets of langerhans can only secrete the utilization promoting sugar of more islets of langerhans usually compensatory, final blood glucose can be relatively higher than normal level, i.e. so-called insulin-resistant states, leads diabetogenic generation. According to investigations in the crowd of more than 20 years old, the prevalence of metabolic syndrome is 14%-16%. Metabolic syndrome increases along with increasing of age, census of population shows, the average prevalence of metabolic syndrome 20.6% of sample population is compared, the prevalence of more than 40 years old each age group crowds increases in gradually rising trend with the age, increased to 27.34% prevalence of 70 years old age bracket by 23.42% prevalence of 40 years old age bracket gradually, be all remarkably higher than average prevalence. And the cardiovascular event probability of happening that the diabetes that metabolic syndrome is brought out cause is 4.5 times of normal person; The probability that metabolic syndrome patients dies from apoplexy, suffer from heart failure is more high than common people.
Preventing and treating metabolic syndrome, main target is prevention clinical cardiovascular disease and type 2 diabetes mellitus, reduces cardiovascular danger event, reduces invalid and dead incidence rate.At present, the Therapeutic Method of metabolic syndrome is mainly through motion, diet and medicine control etc. Patent search result finds, metabolic syndrome is prevented and treated, domestic and international patent focuses mostly on and is passing through the different oral drug preparation of exploitation, the display majority invention of Chinese patent result adopts natural drug (No.201110328074.4) and pharmaceutical composition (No.200910263426.5) etc. to prevent and treat metabolic syndrome, in addition with utilizing tubular vest (No.200990100313.7) and belt (No.201120037962.6) prophylactic treatment metabolic syndrome. European patent retrieval found that, prevent and treat in Patents with metabolic syndrome, adopt L-Carnitine (L-carnitine) Patents preventing and treating metabolic syndrome to be intended to exploitation oral drug preparation, for instance patent No.JP2008291002 and patent CN1443575 more. Also propose to adopt radium-shine laser to directly act on fatty tissue at European patent No.US2011251659, play reduction blood pressure and blood lipoid effect by starting Adipocyte Factor. U.S. Patent search result then shows and reaches 268 patented inventions relevant to L-carnitine (L-carnitine), it is mainly intended to develop oral formulations and prevents and treats metabolic syndrome, as patent No.8389574 utilizes acety-L-carnitine (acetyl-L-carnitine) to prevent and treat type 2 diabetes mellitus and insulin-resistant states. In sum, the domestic and international patent issued at present focuses mostly on passing through different its purpose of oral drug preparation of exploitation all controlling metabolic syndrome patients's body weight and blood glucose, blood fat or blood pressure, thus playing prophylactic treatment effect.
The method preventing and treating metabolic syndrome stated such as above-mentioned more than one piece publication, mainly by strengthening physical training, is gone on a diet and three kinds of methods of oral medicine is to reach its purpose. Said method also exists without real-time operability, or affects nutrition intake and balance, or there are one or more shortcomings such as oral medicine first pass effect. Additionally, above-mentioned patent is all without by transdermal test in vitro formulation load L-Carnitine (L-carnitine), reach to prevent and treat the function of metabolic syndrome. By the retrieval to numerous bibliographic data bases, do not find to adopt clothing as the carrier of L-Carnitine (L-carnitine) and by nano-oxide assosting effect, based on Drug Percutaneous Absorption principle, by disturbing response to oxidative stress to reach to improve the report of metabolic syndrome.
Summary of the invention
The technical problem to be solved in the present invention is in that, also exist without real-time operability for prior art, or affect nutrition intake and balance, or there are one or more shortcoming drawbacks described above such as oral medicine first pass effect, there is provided a kind of carrier using clothing as L-Carnitine (L-carnitine) and by nano-oxide assosting effect, based on Drug Percutaneous Absorption principle, by disturbing response to oxidative stress to reach to improve the function clothes of metabolic syndrome.
The technical solution adopted for the present invention to solve the technical problems is: a kind of function clothes improving metabolic syndrome, the raw material of described function clothes includes functional layer fabric, described functional layer fabric includes the first outer surface and the first inner surface, described first inner surface is to be processed under the first default process conditions by the first auxiliary agent preset and obtain, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water,Described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time; The condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time.
Preferably, described functional layer fabric is made up of one of knitting, tatting or non-woven fabric, the organizational structure of described functional layer fabric is one of one side, rib-loop, mesh, four kinds of forms of tuck, and the elastic recovery strain of described functional layer fabric is more than 20%.
Preferably, the raw material of described function clothes also includes auxiliary functional layer fabric, and described auxiliary functional layer fabric is made up of one of tatting, knitting, non-woven fabrics or porous flake flexible fabric.
Preferably, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, described fat reducing fat district is adopted the second auxiliary agent preset to carry out arrangement under the second default process conditions by the described functional layer fabric processed through one side or described auxiliary functional layer fabric and forms, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water, described second technique is for be sprayed on described functional layer fabric or described auxiliary functional layer fabric by described second auxiliary agent, or described functional layer fabric or described auxiliary functional layer fabric are immersed in described second auxiliary agent, then naturally dry or 25 DEG C of oven drying at low temperatures.
Preferably, described 3rd thickening agent is food grade thickener.
Preferably, described first outer surface is provided with the coating for carrying out hydrophobic treatment.
Preferably, described auxiliary functional layer fabric is fixed/is adhered on described first inner surface of described functional layer fabric.
Preferably, the raw material of described function clothes also includes the moisture-keeping functions layer fabric that vapor transfer rate is controlled, described moisture-keeping functions layer fabric is fitted on described first outer surface of described functional layer fabric by the method for coating or pad pasting, and the fabric vapor transfer rate of described moisture-keeping functions layer fabric is at 3000-25000g/m2Between d.
The manufacture method of a kind of function clothes improving metabolic syndrome, described method comprises the steps:
S1, one of knitting, tatting or non-woven fabric cut out and form functional layer fabric, cut out by one of tatting, knitting, non-woven fabrics or porous flake flexible fabric and form auxiliary functional layer fabric, described functional layer fabric includes the first inner surface and the first outer surface, by vapor transfer rate at 3000-25000g/m2Fabric functional layer fabric between d cuts out formation moisture-keeping functions layer fabric;
S2, adopt the first auxiliary agent preset to carry out processing under the first default process conditions in described functional layer fabric and form the first inner surface, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water,Described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time; The condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time;
S3, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, the second auxiliary agent preset is adopted to arrange under the second default process conditions in described auxiliary functional layer fabric, described second auxiliary agent includes the second solute and the second solvent, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water, described second technique is for be sprayed on described auxiliary functional layer fabric by described second auxiliary agent, or described auxiliary functional layer fabric is immersed in described second auxiliary agent, then naturally dries or 25 DEG C of oven drying at low temperatures,
S4, on described first outer surface, it is arranged to carry out the coating of hydrophobic treatment;
S5, described auxiliary functional layer fabric is fixed/adhere on described first inner surface of described functional layer fabric;
S6, described moisture-keeping functions layer fabric is fitted on described first outer surface by the method for coating or pad pasting;
S7, described functional layer fabric, auxiliary functional layer fabric, moisture-keeping functions layer fabric are made by cutting and form described function clothes.
Alternatively, the manufacture method of a kind of function clothes improving metabolic syndrome, described method comprises the steps:
S1, one of knitting, tatting or non-woven fabric cutting out and form functional layer fabric, described functional layer fabric includes the first inner surface and the first outer surface, by vapor transfer rate at 3000-25000g/m2Formation moisture-keeping functions layer fabric cut out by fabric between d;
S2, adopt the first auxiliary agent preset to carry out processing under the first default process conditions in described functional layer fabric and form the first inner surface, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water, described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time, the condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time,
S3, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, the second auxiliary agent preset is adopted to arrange under the second default process conditions in the fat reducing fat district of described functional layer fabric, described second auxiliary agent includes the second solute and the second solvent, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water,Described second technique is be sprayed in the fat reducing fat district of described functional layer fabric by described second auxiliary agent; Or the fat reducing fat district of described functional layer fabric is immersed in described second auxiliary agent, then naturally dries or 25 DEG C of oven drying at low temperatures;
S4, on described first outer surface, it is arranged to carry out the coating of hydrophobic treatment;
S5, described moisture-keeping functions layer fabric is fitted on described first outer surface by the method for coating or pad pasting;
S6, described functional layer fabric, moisture-keeping functions layer fabric are made by cutting and form described function clothes.
Enforcement the invention has the beneficial effects as follows: this function clothes are a kind of direct and contact skin clothing, its outer surface has good hydrophobic function, control by hydrophilic, the warming and fabulous airing function that its inner surface is good, utilize the warm and humid environment construction drug transdermal delivery system of skin surface, assist little molecular hydrophylic medicine L-carnitine Transdermal absorption, user wears this function clothes for a long time, can improve insulin and the secretion of fat correlation factor, and then improve metabolic syndrome. It is simple to operate that corresponding function provided by the invention takes manufacture method, with low cost.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing:
Fig. 1 is the structural representation that the present invention improves the multilamellar function fabric of the product embodiments 1 of the function clothes of metabolic syndrome;
Fig. 2 is the structure front view that the present invention improves one shell type close-fitting vest ready-made clothes of surplus of the product embodiments 1 of the function clothes of metabolic syndrome;
Fig. 3 is the structure rearview that the present invention improves one shell type close-fitting vest ready-made clothes of surplus of the product embodiments 1 of the function clothes of metabolic syndrome;
Fig. 4 is the structure front view that the present invention improves the surplus two pieces shell type close-fitting vest ready-made clothes of the product embodiments 2 of the function clothes of metabolic syndrome;
Fig. 5 is the structure rearview that the present invention improves the surplus two pieces shell type close-fitting vest ready-made clothes of the product embodiments 2 of the function clothes of metabolic syndrome;
Fig. 6 is the structure front view that the present invention improves the shortage of money two pieces shell type close-fitting vest ready-made clothes of the product embodiments 2 of the function clothes of metabolic syndrome;
Fig. 7 is the structure rearview that the present invention improves the shortage of money two pieces shell type close-fitting vest ready-made clothes of the product embodiments 2 of the function clothes of metabolic syndrome;
Fig. 8 be the present invention improve metabolic syndrome function clothes product embodiments 3 staylace launch time structural representation;
Fig. 9 be the present invention improve the staylace of the product embodiments 3 of the function clothes of metabolic syndrome folding time structural representation.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated. It should be appreciated that specific embodiment described herein is only used for explaining the present invention, it is not intended to limit the present invention.
Product embodiments 1
As shown in Figure 1, the raw material of these function clothes improving metabolic syndrome includes functional layer fabric C and auxiliary functional layer fabric B, functional layer fabric is made up of one of knitting, tatting or non-woven fabric, the organizational structure of functional layer fabric can be any form, but being preferably one of one side, rib-loop, mesh, four kinds of forms of tuck, the elastic recovery strain of functional layer fabric is more than 20%; Auxiliary functional layer fabric is made up of one of tatting, knitting, non-woven fabrics or porous flake flexible fabric. In the present embodiment, functional layer fabric C is prepared from by the cotton knitting fabric of rib-loop (Shandong absolute sincerity Textile Co., Ltd.) with 15%40D spandex of 85%50S with auxiliary functional layer fabric B both.
Functional layer fabric includes the first outer surface and the first inner surface, first outer surface is provided with the coating for carrying out hydrophobic treatment, the hydrophobic of the first outer surface is made to reach the 5 grades of requirements of ISO-4920 standard, first inner surface is to be processed under the first default process conditions by the first auxiliary agent preset and obtain, first auxiliary agent includes the first solute and the first solvent, first solute includes at the first thickening agent that the mass percent shared by the first auxiliary agent is 2-15%, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, first solvent is deionized water, in the present embodiment, preferred mass percent is the first thickening agent (Dandong Fixed Star Fine Chemical Co., Ltd): 6.5%, the second thickening agent (Dandong Fixed Star Fine Chemical Co., Ltd): 6.5%, binding agent (Dandong Fixed Star Fine Chemical Co., Ltd): 20%, nano-metal-oxide (Aladdin reagent Shanghai company limited): 0.62%, nano woolen polypeptide (technology of preparing is referring to patent WO2010015195A1): 0.5% as the second solute, and the deionized water of 65.88% is as the second solvent.
First technique is: functional layer fabric carrying out one side and processes acquisition the first inner surface, bake after preliminary drying, preliminary drying condition is temperature 80-100 DEG C, is preferably 100 DEG C, can also be preferably 90 DEG C in the present embodiment; Preliminary drying time is 3-5 minute, is preferably 3 minutes, can also be preferably 4 minutes in the present embodiment; The condition of baking is temperature 130-160 DEG C, is preferably 150 DEG C, bakes the time 3-10 minute in the present embodiment, is preferably 3 minutes, can also be preferably 4 minutes in the present embodiment.
The upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on function takes, the athero portion is fat reducing fat district, fat reducing fat district is adopted the second auxiliary agent preset to carry out arrangement under the second default process conditions by auxiliary functional layer fabric and forms, second auxiliary agent includes the second solute and the second solvent, it is the L-carnitine of 10-30% that second solute includes in the mass percent shared by the second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, second solvent is deionized water, in the present embodiment, preferred mass percent is L-Carnitin (L-carnitine) (Ya Dun medication chemistry company limited): 16%, the 3rd thickening agent (Jiangsu Zhongda Biological Technology Group Co., Ltd.): 6.5%, propylene glycol (orient chemical tech company limited): 2.5%, glycerol (orient chemical tech company limited): 2.5% as solute, and the deionized water of 72.5% is as solvent.
In the present embodiment, the 3rd thickening agent is food grade thickener.
Second technique, for be sprayed on auxiliary functional layer fabric by the second auxiliary agent or to be immersed in the second auxiliary agent by auxiliary functional layer fabric, is then dried or 25 DEG C of oven drying at low temperatures naturally. The present embodiment is preferably the second auxiliary agent is sprayed on auxiliary functional layer fabric, then naturally dry.
Moisture-keeping functions layer fabric A is prepared from by the Radix Saposhnikoviae knitting fabric of dash stretchy nylon (production of Haining Gao Jin Fabritex S.r.l) that a kind of drenched amount is controlled, and the vapor transfer rate of moisture-keeping functions layer fabric is at 3000-25000g/m2Between d, the present embodiment is preferably 15000g/m2D.Moisture-keeping functions layer fabric is fitted on the first outer surface by the method for coating or pad pasting.
Lamination type composite material technology is used in the present embodiment, and the auxiliary functional layer fabric after process is fitted on the first inner surface of functional layer fabric with a patch method, becomes the multilamellar function fabric with medicine carrying function.
Treated multilamellar function fabric has following performance:
1, the elastic recovery strain of multilamellar function fabric is 30%;
2, the face of the nearly skin of multilamellar function fabric and inner surface have special function: have good hydrophilic and fabulous airing function, and its opposing face has good hydrophobic function and makes perspiration be accumulated in the skin surface infiltration for medicine as much as possible;
3, measuring according to JISL1099 standard, the vapor transfer rate of multilamellar function fabric reaches 15000g/m2D;
4, FRMT observes that multilamellar function fabric possesses infrared property, and therefrom it is observed that after stable state infrared intensity all strengthen to some extent. (the concrete measurement about infrared property is referred to the patent 200410068752.8 of the present inventor for measuring the apparatus and method of the infrared radiation characteristic of fabric).
5, SEM paired observation is carried out, it is clear that the inner surface success load of multilamellar function fabric L-carnitine L-Carnitine is seen on ground.
6, contrast untreated front auxiliary functional layer fabric, auxiliary functional layer fabric after treatment have found L-Carnitine at 940cm-1��1480cm-1And 1582cm-1Characteristic group. FTIR figure observes that carrying out auxiliary functional layer fabric possesses L-Carnitine characteristic group after treatment, it was demonstrated that auxiliary functional layer fabric success load L-Carnitine.
As shown in Figure 2,3, functional layer fabric, moisture-keeping functions layer fabric and auxiliary functional layer fabric splicing seams is adopted to make man or one shell type close-fitting vest ready-made clothes of female's surplus. Functional layer fabric and moisture-keeping functions layer fabric all envelope the position that human body needs clothes to be coated with, including upper arm a, shoulder b, chest c, abdominal part d, waist e, thigh f, buttocks g, shank h, crook of the arm i, wrist j regional, and adjuvant layer is only applied in the region that position that all or part of body fat easily gathers is corresponding, region includes the clothes position corresponding to the upper arm a of human body, thigh f, waist e, abdominal part d, buttocks g, and auxiliary functional layer fabric is sticked on the first inner surface of functional layer fabric.
As shown in Figure 4,5, man or female's surplus two pieces shell type close-fitting vest ready-made clothes are made with functional layer fabric, moisture-keeping functions layer fabric and auxiliary functional layer fabric splicing seams.
Product embodiments 2
The fabric that this product embodiments adopts is essentially identical with product embodiments 1 with process technique, repeats no more herein.
Such as Fig. 6, 7 adopt functional layer fabric, moisture-keeping functions layer fabric and moisture-keeping functions layer fabric splicing seams make men and women's shortage of money two pieces shell type close-fitting vest ready-made clothes, and ensure the elastic force conformability designed at each position, functional layer fabric and moisture-keeping functions layer fabric all envelope the position that human body needs clothes to be coated with, including upper arm a, shoulder b, chest c, abdominal part d, waist e, thigh f, buttocks g, crook of the arm i, wrist j regional, for reducing cost, auxiliary functional layer fabric is only applied in the region that position that all or part of body fat easily gathers is corresponding, region includes the upper arm a of human body, thigh f, waist e, abdominal part d, clothes position corresponding to buttocks g.
Auxiliary functional layer fabric directly can also be layered on the skin of the easy accumulation region of body fat of required effect, then put on the clothing being made up of functional layer fabric or device is fixed.
Auxiliary functional layer fabric non-woven fabrics (Rongsheng Non-woven Cloth Co Ltd, Guangzhou) can also made in the second additive latex two leaching two roll (band liquid measure 400%) after, insert in vacuum packaging bag seal preserve. When needs use, just auxiliary functional layer fabric is sticked on the first inner surface of functional layer fabric so that the cutting of fabric possesses certain motility.
Product embodiments 3
As shown in Figure 8,9, the multilamellar function fabric that product embodiments 1 is processed into is adopted to make staylace. M is the multilamellar function fabric that product embodiments 1 is processed into, and N is tearing button. The special device reaching the reinforcement administration of certain some specific region and design can also be made for, including being not limited to arm sleeve, trick muffetee etc.
The clothing of this patent design are a kind of direct and contact skin clothing, this function clothes are a kind of direct and contact skin clothing, its outer surface has good hydrophobic function, control by the hydrophilic and fabulous airing function that its inner surface is good, reach the temperature to skin surface and humidity carries out function application, utilize the warm and humid environment construction drug transdermal delivery system of skin surface, assist little molecular hydrophylic medicine L-carnitine Transdermal absorption.
Owing in auxiliary agent, transdermal blood is penetrated in the sustainable release of L-Carnitine (L-carnitine), play it and reduce oxidative stress, effect of prevention and treatment metabolic syndrome. The long-term clothes wearing the present invention can improve the secretion of insulin correlation factor. This includes promoting the secretion that glucose transportation test (Glut-4) reduces tumor necrosis factor-alpha (tumornecrosisfactor-��, TNF-��) simultaneously. The secretion of fat correlation factor can also be improved. This secretion including reducing interleukin-6 (IL-6) and tumor necrosis factor-alpha (tumornecrosisfactor-��, TNF-��); Promote the generation of leptin Leptin; Can reduce simultaneously, regulate response to oxidative stress. This includes reducing intracellular reactive oxygen clusters (ROS); Reduce Plasma SOD (SOD); Serum MDA (MAD); The concentration of the different dinoprost of serum 8-(8-iso-PFG2 ��).
To sum up, this patent can realize real-time controlled transdermal administration, and user can determine to wear the time according to needs, does not affect daily life and alimentation, is absent from the advantages such as first pass effect simultaneously.
Embodiment of the method 1
The present invention also provides for the manufacture method of a kind of function clothes improving metabolic syndrome, and method comprises the steps:
S1, one of knitting, tatting or non-woven fabric cut out and form functional layer fabric, cut out by one of tatting, knitting, non-woven fabrics or porous flake flexible fabric and form auxiliary functional layer fabric, functional layer fabric includes the first inner surface and the first outer surface, by vapor transfer rate at 3000-25000g/m2Formation moisture-keeping functions layer fabric cut out by fabric between d;
S2, functional layer fabric adopt the first auxiliary agent preset carry out processing under the first default process conditions and form the first inner surface, first auxiliary agent includes the first solute and the first solvent, first solute includes the nano woolen polypeptide at the first thickening agent that the mass percent shared by the first auxiliary agent is 2-15%, mass percent to be second thickening agent of 2-15%, mass percent the be binding agent of 10-25%, mass percent to be the nano-metal-oxide of 0.5-1%, mass percent be 0.2-0.6%, and the first solvent is deionized water; First technique is: one side processes and obtains the first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time;The condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time;
S3, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on function takes, the athero portion is fat reducing fat district, the second auxiliary agent preset is adopted to arrange under the second default process conditions in auxiliary functional layer fabric, second auxiliary agent includes the second solute and the second solvent, second auxiliary agent includes the second solute and the second solvent, it is the L-carnitine of 10-30% that second solute includes in the mass percent shared by the second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, second solvent is deionized water, second technique is for be sprayed on auxiliary functional layer fabric by the second auxiliary agent, or auxiliary functional layer fabric is immersed in the second auxiliary agent, then naturally dries or 25 DEG C of oven drying at low temperatures,
S4, on the first outer surface, it is arranged to carry out the coating of hydrophobic treatment;
S5, auxiliary functional layer fabric is fixed/adhere on the first inner surface of functional layer fabric;
S6, moisture-keeping functions layer fabric is fitted on the first outer surface by the method for coating or pad pasting;
S7, functional layer fabric, auxiliary functional layer fabric, moisture-keeping functions layer fabric are made by cutting and form function clothes.
Embodiment of the method 2
Also providing for the manufacture method that another kind improves the function clothes of metabolic syndrome, described method comprises the steps:
S1, one of knitting, tatting or non-woven fabric cutting out and form functional layer fabric, described functional layer fabric includes the first inner surface and the first outer surface, by vapor transfer rate at 3000-25000g/m2Formation moisture-keeping functions layer fabric cut out by fabric between d;
S2, adopt the first auxiliary agent preset to carry out processing under the first default process conditions in described functional layer fabric and form the first inner surface, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water, described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time, the condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time,
S3, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, the second auxiliary agent preset is adopted to arrange under the second default process conditions in the fat reducing fat district of described functional layer fabric, described second auxiliary agent includes the second solute and the second solvent, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water, described second technique is be sprayed in the fat reducing fat district of described functional layer fabric by described second auxiliary agent,Or the fat reducing fat district of described functional layer fabric is immersed in described second auxiliary agent, then naturally dries or 25 DEG C of oven drying at low temperatures;
S4, on described first outer surface, it is arranged to carry out the coating of hydrophobic treatment;
S5, described moisture-keeping functions layer fabric is fitted on described first outer surface by the method for coating or pad pasting;
S6, described functional layer fabric, moisture-keeping functions layer fabric are made by cutting and form described function clothes.
Above in association with specific embodiment, the present invention is expanded on further. But these embodiments are merely to illustrate the present invention rather than for limiting the practical range of the present invention. Additionally, it will be understood that after reading present disclosure, the present invention can be done various change and amendment by relevant technical staff in the field, and these equivalent form of values fall within the scope defined in claim appended by the application equally.
Claims (9)
1. the function clothes improving metabolic syndrome, it is characterized in that: the raw material of described function clothes includes functional layer fabric, described functional layer fabric includes the first outer surface and the first inner surface, described first inner surface is to be processed under the first default process conditions by the first auxiliary agent preset and obtain, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water, described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time, the condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time.
2. improve the function clothes of metabolic syndrome as claimed in claim 1, it is characterized in that: described functional layer fabric is made up of one of knitting, tatting or non-woven fabric, the organizational structure of described functional layer fabric is one of one side, rib-loop, mesh, four kinds of forms of tuck, and the elastic recovery strain of described functional layer fabric is more than 20%; The raw material of described function clothes also includes auxiliary functional layer fabric, and described auxiliary functional layer fabric is made up of one of tatting, knitting, non-woven fabrics or porous flake flexible fabric.
3. improve the function clothes of metabolic syndrome as claimed in claim 2, it is characterized in that: the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is predefined as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, described fat reducing fat district is adopted the second auxiliary agent preset to carry out arrangement under the second default process conditions by the described functional layer fabric processed through one side or described auxiliary functional layer fabric and forms, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water, described second technique is for be sprayed on described functional layer fabric or described auxiliary functional layer fabric by described second auxiliary agent,Or described functional layer fabric or described auxiliary functional layer fabric are immersed in described second auxiliary agent, then naturally dry or 25 DEG C of oven drying at low temperatures.
4. improve the function clothes of metabolic syndrome as claimed in claim 3, it is characterised in that: described 3rd thickening agent is food grade thickener.
5. improve the function clothes of metabolic syndrome as claimed in claim 4, it is characterised in that: described first outer surface is provided with the coating for carrying out hydrophobic treatment.
6. improve the function clothes of metabolic syndrome as claimed in claim 5, it is characterised in that: described auxiliary functional layer fabric is fixed/is adhered on described first inner surface of described functional layer fabric.
7. improve the function clothes of metabolic syndrome as claimed in claim 6, it is characterized in that: the raw material of described function clothes also includes the moisture-keeping functions layer fabric that vapor transfer rate is controlled, described moisture-keeping functions layer fabric is fitted on described first outer surface of described functional layer fabric by the method for coating or pad pasting, and the fabric vapor transfer rate of described moisture-keeping functions layer fabric is at 3000-25000g/m2Between d.
8. the manufacture method of the function clothes improving metabolic syndrome, it is characterised in that: described method comprises the steps:
S1, one of knitting, tatting or non-woven fabric cut out and form functional layer fabric, described functional layer fabric includes the first inner surface and the first outer surface, cut out by one of tatting, knitting, non-woven fabrics or porous flake flexible fabric and form auxiliary functional layer fabric, by vapor transfer rate at 3000-25000g/m2Formation moisture-keeping functions layer fabric cut out by fabric between d;
S2, adopt the first auxiliary agent preset to carry out processing under the first default process conditions in described functional layer fabric and form the first inner surface, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water, described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time, the condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time,
S3, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, the second auxiliary agent preset is adopted to arrange under the second default process conditions in described auxiliary functional layer fabric, described second auxiliary agent includes the second solute and the second solvent, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water, described second technique is for be sprayed on described auxiliary functional layer fabric by described second auxiliary agent, or described auxiliary functional layer fabric is immersed in described second auxiliary agent, then naturally dries or 25 DEG C of oven drying at low temperatures,
S4, on described first outer surface, it is arranged to carry out the coating of hydrophobic treatment;
S5, described auxiliary functional layer fabric is fixed/adhere on described first inner surface of described functional layer fabric;
S6, described moisture-keeping functions layer fabric is fitted on described first outer surface by the method for coating or pad pasting;
S7, described functional layer fabric, auxiliary functional layer fabric, moisture-keeping functions layer fabric are made by cutting and form described function clothes.
9. the manufacture method of the function clothes improving metabolic syndrome, it is characterised in that: described method comprises the steps:
S1, one of knitting, tatting or non-woven fabric cutting out and form functional layer fabric, described functional layer fabric includes the first inner surface and the first outer surface, by vapor transfer rate at 3000-25000g/m2Formation moisture-keeping functions layer fabric cut out by fabric between d;
S2, adopt the first auxiliary agent preset to carry out processing under the first default process conditions in described functional layer fabric and form the first inner surface, described first auxiliary agent includes the first solute and the first solvent, described first solute includes at the first thickening agent that mass percent is 2-15% shared by described first auxiliary agent, mass percent is second thickening agent of 2-15%, mass percent is the binding agent of 10-25%, mass percent is the nano-metal-oxide of 0.5-1%, mass percent is the nano woolen polypeptide of 0.2-0.6%, described first solvent is deionized water, described first technique is: one side processes and obtains described first inner surface, bakes after preliminary drying, and wherein preliminary drying condition is temperature 80-100 DEG C, 3-5 minute time, the condition that wherein bakes is temperature 130-160 DEG C, 3-10 minute time,
S3, the upper arm of human body, thigh, waist, abdominal part, buttocks is the position that fat is easily piled up, it is preset as athero portion, corresponding region on described function takes, the described athero portion is fat reducing fat district, the second auxiliary agent preset is adopted to arrange under the second default process conditions in the fat reducing fat district of described functional layer fabric, described second auxiliary agent includes the second solute and the second solvent, described second auxiliary agent includes the second solute and the second solvent, described second solute includes at the L-carnitine that mass percent is 10-30% shared by described second auxiliary agent, mass percent is the 3rd thickening agent of 2%-15%, mass percent is the propylene glycol of 2%-10%, mass percent is the glycerol of 0-10%, described second solvent is deionized water, described second technique is be sprayed in the fat reducing fat district of described functional layer fabric by described second auxiliary agent, or the fat reducing fat district of described functional layer fabric is immersed in described second auxiliary agent, then naturally dries or 25 DEG C of oven drying at low temperatures,
S4, on described first outer surface, it is arranged to carry out the coating of hydrophobic treatment;
S5, described moisture-keeping functions layer fabric is fitted on described first outer surface by the method for coating or pad pasting;
S6, described functional layer fabric, moisture-keeping functions layer fabric are made by cutting and form described function clothes.
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| CN201410033574.9A CN104799440B (en) | 2014-01-23 | 2014-01-23 | Improve function clothes and the manufacture method thereof of metabolic syndrome |
| PCT/CN2015/070681 WO2015109964A1 (en) | 2014-01-23 | 2015-01-14 | Functional clothing for alleviating metabolic syndrome and manufacturing method thereof |
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| CN201410033574.9A CN104799440B (en) | 2014-01-23 | 2014-01-23 | Improve function clothes and the manufacture method thereof of metabolic syndrome |
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| DE102004020714A1 (en) * | 2004-04-26 | 2005-11-10 | Beiersdorf Ag | Skin and / or hair means containing compounds with isoprenoid structure |
| CN200948291Y (en) * | 2006-08-22 | 2007-09-19 | 任智明 | Health caring cloth for the medicine bead transdermal therapy |
| WO2008124105A1 (en) * | 2007-04-04 | 2008-10-16 | Naturegen, Inc. | Compositions and methods for obesity, diabetes and metabolic syndrome control and management |
| JP3144291U (en) * | 2008-06-12 | 2008-08-21 | 琢 横山 | Tuberculosis shirt for metabolic syndrome |
| CN101684616B (en) * | 2008-08-04 | 2012-05-02 | 香港纺织及成衣研发中心 | Function textile with nanometer composite structure produced by nanometer protein material and method of preparation |
| JP2010057873A (en) * | 2008-09-03 | 2010-03-18 | Yukio Morimoto | Thin leg weight |
| JP2010148415A (en) * | 2008-12-25 | 2010-07-08 | Yoshihiro Futamura | Method for producing compound for generating hydrogen gas |
| CN101953516A (en) * | 2010-06-02 | 2011-01-26 | 成钢 | Nanometer element anion far infrared antibacterial textile underwear for modern civil diseases |
| US20130267872A1 (en) * | 2012-04-04 | 2013-10-10 | Amrit Pal Singh Bhangoo | Health risk marker measurement device |
| CN104411321A (en) * | 2012-05-16 | 2015-03-11 | 葛兰素集团有限公司 | Polypeptide loaded poca nanoparticles for oral administration |
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