CN104786277B - Chondroconia acquisition device - Google Patents
Chondroconia acquisition device Download PDFInfo
- Publication number
- CN104786277B CN104786277B CN201510158490.2A CN201510158490A CN104786277B CN 104786277 B CN104786277 B CN 104786277B CN 201510158490 A CN201510158490 A CN 201510158490A CN 104786277 B CN104786277 B CN 104786277B
- Authority
- CN
- China
- Prior art keywords
- chondroconia
- negative pressure
- pressure prevention
- prevention cover
- acquisition device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26F—PERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
- B26F1/00—Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
- B26F1/16—Perforating by tool or tools of the drill type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/22—Safety devices specially adapted for cutting machines
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/27—Means for performing other operations combined with cutting
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Forests & Forestry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Surgical Instruments (AREA)
Abstract
The invention discloses a kind of chondroconia acquisition device, belong to technical field of medical instruments, comprise the crusher drill that cuts chondroconia, collect the gathering system of chondroconia, drive the motor of bit and be sleeved on the Negative pressure prevention cover on crusher drill, described crusher drill front end is spherical or taper cutting head, rear end is abrasive drilling bar, described cutting head surface is provided with and is spiral-distributed wedge shape serrated knife blade, the inner surface of described Negative pressure prevention cover, the blind end of the outer surface of abrasive drilling bar and Negative pressure prevention cover forms ring-type passage of particles, described gathering system comprise be arranged on Negative pressure prevention cover outer can to passage of particles produce the negative pressure device of absorption affinity and be communicated with passage of particles for collecting the collector of chondroconia. this device can disposablely complete chondroconia and produce and collect, and saves time and raises the efficiency, and ensure that chondroconia size is between 100-150 μ m, and cartilage cell's survival rate in particulate is high, division growth ability is strong.
Description
Technical field
The invention belongs to technical field of medical instruments, be specifically related to a kind of chondroconia acquisition device.
Background technology
Articular cartilage defect is clinical common, and 60% above patients with knee arthroscopy is with cartilage defect according to statistics,Wherein 42% is focal hyaline cartilage defect, and the damaged degree of depth is no more than calcified cartilage layer, damaged faceAmass at 2～4cm2Between. Because hyaline cartilage does not have blood vessel, nerve and lymphatic system, natural repair abilityLowly, diameter exceedes the damaged of 4mm and almost can not repair completely. If do not treated in time, damage willContinue to increase the weight of and cause arthritis, occur arthralgia swelling, deformity. For this type of cartilage defect, traditionTherapeutic strategy is in art, to adopt micro-fracture method that marrow blood is oozed out, and utilizes the mescenchymal stem cell in blood clotPropagation, reparation cartilage defect, but final formation is the poor fibrocartilage of wearability. Along with organizational projectThe fast development of technology, autologous chondrocyte cell transplantation technology is gradually at clinical application, but this Technology NeedAutologous cartilage cell is carried out to amplification in vitro, and then second operation is implanted; Because being difficult to simulation, in vitro culture existsBody microenvironment, especially lacks the monitoring of body immune system, and the cartilage cell of implantation shows conventionallyType changes, and therefore the final repair tissue forming structurally or on composition all exists with natural cartilageEssential difference, is difficult to guarantee the long-term effectiveness of its treatment.
For the problems referred to above, we propose: adopt autologous chondroconia transplantation strategies by external cartilage cell expansionIncreasing process is transferred in body, avoids it to dedifferente; Be aided with fabrication of cartilage matrix colloidal sol disperses with solid simultaneouslyFixed, utilize in body microenvironment and realize chondrocyte proliferation, secretion matrix, regeneration high-quality articular cartilage. BeforePhase research shows that articular chondrocytes averag density is 14000/mm3, can adopt mechanical means by cartilagePulverize, prepare micron order cartilage particle, make each particle comprise the cartilage cell with multiplication capacity,Then after compound with fabrication of cartilage matrix colloidal sol, implant. Cartilage cell in chondroconia utilizes micro-at bodyEnvironment, matrix is bred, secreted to simulation natural cartilage forming process, Regeneration and Repair cartilage defect.
With the autologous chondrocyte cell transplantation technology ratio of tradition, this strategy has following advantage: adopt mechanical crushing sideMethod, in chondroconia mode, the cartilage cell in cartilage is disperseed, without cartilage cell is separated withAmplification, is aided with bionical matrix colloidal sol and once performs the operation and can complete; Utilize in body microenvironment and realize cartilage cell's increasingGrow, avoid amplification in vitro to cause that cartilage cell dedifferentes, thereby improve regeneration of cartilage quality; From cartilage defectEdge obtains a small amount of autologous cartilage, and twice laid can Min. reduce wound, and is not subject to cartilage defect shapeShape restriction. After this project implementation, be expected to realize in art and find that focal articular cartilage defect can enter in timeRow is repaired, and stops it and causes arthritis pathology process, removes patient's pain, recovers joint motions function, toolHave wide practical use.
But, realize above-mentioned target, first need to solve autologous chondroconia technology of preparing problem. Grind early stageStudy carefully and show, the chondrocyte proliferation ability of particle diameter in the particulate of 100-150 μ m is the strongest, but how efficiently to obtainGet the chondroconia of this particle size range? and reduce to greatest extent the mechanical damage of cartilage cell in preparation process?To realize above-mentioned target to be badly in need of the key technical problem solving. In early-stage Study, we attempt adopting artificialThe method of cutting is prepared chondroconia, although can ensure the proliferation activity of cartilage cell in particulate, has grainThe problems such as footpath size is difficult to control, labour intensity is large, efficiency is low; Although adopt grinder buffing mode particle diameter largeLittle controlled, and particulate is even, efficiency is high, but it is because emery wheel can produce heat in bruting process, causesCartilage cell in particulate loses activity, and cannot realize chondrocyte proliferation.
Therefore, be necessary to develop a kind of autologous chondroconia acquisition device, effective acquisition particle diameter is at 100-150 μThe chondroconia of m, reduces the mechanical damage of cartilage cell in preparation process simultaneously to greatest extent, ensures cartilageCartilage cell's proliferation activity in particulate.
Summary of the invention
In view of this, the object of patent of the present invention is to develop a kind of autologous chondroconia acquisition device solution certainlyBody chondroconia technology of preparing problem, use this device can effective acquisition particle diameter at the cartilage of 100-150 μ mParticulate, reduces the mechanical damage of cartilage cell in preparation process simultaneously to greatest extent, ensures in chondroconia softThe proliferation activity of osteocyte. Solve the particle size existing in prior art simultaneously and be difficult to control, labour intensityThe active problem such as low of chondrocyte proliferation greatly.
The object of the invention is to be achieved through the following technical solutions:
Chondroconia acquisition device of the present invention, comprises that crusher drill, the collection cartilage for cutting chondroconia is micro-The gathering system of grain, drive the motor of crusher drill High Rotation Speed and be sleeved on the Negative pressure prevention cover on crusher drill,Described crusher drill front end is spherical or taper cutting head, and rear end is abrasive drilling bar, and described cutting head surface is provided withBe spiral-distributed wedge shape serrated knife blade, described Negative pressure prevention cover is the tubulose of an end opening, other end sealingStructure, its blind end is provided with the abrasive drilling bar via hole on abrasive drilling bar that is sleeved on that safety protective cover can be sealed,The cutting head of its openend and crusher drill forms ring-type particulate entrance, inner surface, the mill of described Negative pressure prevention coverThe blind end of the outer surface of drilling rod and Negative pressure prevention cover forms ring-type passage of particles, and the far-end of described abrasive drilling bar prolongsStretch out Negative pressure prevention cover and fix with the driving shaft of motor, outside described gathering system comprises that being arranged on Negative pressure prevention overlapsCan to passage of particles produce the vavuum pump of absorption affinity and be communicated with passage of particles for collecting the receipts of chondroconiaStorage, described gathering system also comprises the water injector that can dilute particulate, described water injector comprisesBe arranged on the outer water jet pump being communicated with passage of particles of Negative pressure prevention cover.
Further, between described wedge shape serrated knife blade and be provided with multiple microparticle pores, described abrasive drilling between sawtoothThe abrasive drilling bar of head is hollow tube, and the front end of described hollow tube is communicated with described microparticle pores, and its rear end is sealed with plugLive.
Further, described hollow tube enters respectively the entrance place of Negative pressure prevention cover at vavuum pump and water jet pumpOn two cross sections, being provided with multiple tap holes that are distributed on its circumference is communicated with passage of particles.
Further, the end of the anti-cover of described safety is provided with the protective cover conformal with boring bistrique cutting head.
Further, described collector is disposable box, between described disposable box and Negative pressure prevention cover, be provided with forBe flexibly connected the cassette holder of disposable box, described flexible connection is be arranged on the projection of disposable box oral area outer wall and arrangeOn cassette holder, with the groove of the mutual close-fitting of projection, described flexible connection is at least two, and is distributed on disposable boxSurrounding with cassette holder.
Further, the diameter of the spherical or conical cutting head of described crusher drill is 2-5mm.
Further, the high 100-150 μ of described wedge shape serrated knife blade m, the spacing between two adjacent edge is100-150μm。
Further, the aperture of described microparticle pores is 100-150 μ m.
Further, the caliber of described hollow tube is 150-800 μ m.
Further, also comprise the shell that is arranged on outside motor, on described shell, be also provided with gauge tap byButton.
Beneficial effect of the present invention is:
1, by crusher drill and Negative pressure prevention cover are set, and crusher drill is arranged on in Negative pressure prevention cover, formation canProduce the passage of particles that negative pressure is collected particulate, can, in producing chondroconia, also can carry out softThe collection of bone, the disposable process that completes cutting particulate and collect particulate, significantly saves and produces the time, improvesProduce efficiency, meanwhile, because Negative pressure prevention cover can have protective effect to operating process, make to produce particulate mistakeCheng Gengjia safety.
2, the dark and blade spacing of blade is all set to 100-150 μ m, can ensures particle size evenly and protectCard, in 100-150 μ m, makes that cartilage cell's survival rate in particulate is high, division growth ability is strong.
3, by aperture 100-150 μ m microparticle pores being set and being communicated with passage of particles by hollow tube, it is micro-Grain passage is connected with vavuum pump and water jet pump, and one side, can be by hollow tube to cartilage producing in processThe particulate dilution of spraying water, in collection process, can receive dilution particulate by hollow tube on the other handCollection, and size in chondroconia can be controlled within the scope of 100-150 μ m, excessive particulate impact propagation avoidedAbility, has increased another passage and has produced and collected chondroconia, can avoid particulate in cutting headCongestion affects is produced efficiency.
4, the present invention is owing to being do mechanization operation, and taked binary channels operation, solved in prior art and depositedProduce the easy deactivated problem of particulate that large, the autologous cartilage source demand of labour intensity is large and produce,Have advantages of simple in structure, easy to operate, to produce efficiency high, and the chondroconia size of producing is only100-150 μ m, multiplication capacity are strong, few to autologous cartilage source demand, have slowed down patient and produce the pain of cartilageHardship, has also slowed down cartilage patient's treatment cycle simultaneously greatly, to realizing " the bionical structure of tissue engineering bone/cartilage "Theory provides prerequisite guarantee.
Brief description of the drawings
In order to make object of the present invention, technical scheme and beneficial effect clearer, the invention provides attached as followsFigure describes:
Fig. 1 is chondroconia acquisition device structural representation of the present invention.
Reference numeral: 1-crusher drill; 2-Negative pressure prevention cover; 3-cutting head; 4-abrasive drilling bar; 5-motor; 6-dividesDischarge orifice; 7-hollow tube; 8-cassette holder; 9-disposable box; 10-vavuum pump; 11-projection; 12-groove; 13-shell;14-gauge tap button; 15-passage of particles; 16-wedge shape serrated knife blade; 17-microparticle pores; 18-Hong water pump;19-sealing ring; 20-protective cover; 21-sawtooth.
Detailed description of the invention
Below in conjunction with accompanying drawing, the preferred embodiments of the present invention are described in detail.
As shown in Figure 1, comprise crusher drill 1 for cutting chondroconia, collect chondroconia gathering system,Drive the motor 5 of crusher drill 1 High Rotation Speed and be sleeved on the Negative pressure prevention cover 2 on crusher drill 1, described abrasive drilling1 front end is spherical or taper cutting head 3, and rear end is abrasive drilling bar 4, and described cutting head 3 surfaces are provided with and areSpiral-distributed wedge shape serrated knife blade 16, the thickness of wedge shape serrated knife blade 16 is by cutting head 3 and abrasive drilling bar 4Junction surface to wedge shape serrated knife blade 16 reduce gradually foremost form smear metal portion cartilage cut, andSawtooth 21 also has dissection to cartilage, and cartilage is further reduced, and described Negative pressure prevention cover 2 is for opening one endThe tubular structure of mouth, other end sealing, its blind end is provided with can be by the mill that is sleeved on of safety protective cover sealingAbrasive drilling bar via hole on drilling rod, the cutting head of its openend and crusher drill forms ring-type particulate entrance, described negativePress inner surface, the outer surface of abrasive drilling bar and the blind end of Negative pressure prevention cover of protective jacket to form ring-type passage of particles15, the far-end of described abrasive drilling bar 4 extends Negative pressure prevention cover 2 to be fixed with the driving shaft of motor, due to low speedFrictional heat, damage is large, and motor 5 rotating speeds of the present embodiment are controlled within the scope of 4000-15000r/min, driveThe instantaneous cutting of rotary bistrique high speed, little to the damage of chondroconia, the activity of its cell is better, and described collection isTurnkey is drawn together and is arranged on outer negative pressure device and and the passage of particles that can produce to passage of particles absorption affinity of Negative pressure prevention coverBe communicated with for collecting the collector of chondroconia, described negative pressure device is vavuum pump 10.
The present embodiment overlaps 2 by crusher drill 1 and Negative pressure prevention are set, and crusher drill 1 is arranged on to Negative pressure preventionIn cover 2, prevent in the inner surface of Negative pressure prevention cover 2, outer surface and the negative pressure of abrasive drilling bar 4 by vavuum pump 10The interior generation negative pressure of ring-type passage of particles 15 that the blind end of sheath 2 forms is collected particulate, can produce softWhen bone particulate, also can carry out the collection of cartilage, the disposable mistake that completes cutting particulate and collect particulateJourney, significantly saves and produces the time, and improve and produce efficiency, meanwhile, because Negative pressure prevention cover can be to operating processThere is protective effect, make to produce particulate process safer.
As the improvement of the present embodiment, described gathering system also comprises the water injector that can dilute particulate,Described water injector comprises that being arranged on Negative pressure prevention overlaps the 2 outer water jet pumps 18 that are communicated with passage of particles 15. Pass throughWater jet pump 18 can be producing in process, can be by hollow tube 7 to the chondroconia dilution of spraying water, by cartilageParticulate becomes cartilage solution.
As the improvement of the present embodiment, between described wedge shape serrated knife blade 16 and be provided with many between sawtooth 21Individual microparticle pores 17, the abrasive drilling bar of described crusher drill is hollow tube 7, the front end of described hollow tube 7 and described micro-Grain hole 17 is communicated with, and its rear end seals with plug, and described hollow tube 7 is respectively at vavuum pump 10 and water jet pump 18Enter on two cross sections at entrance place of Negative pressure prevention cover 2, be provided with multiple be distributed on its circumference pointDischarge orifice 6 is communicated with passage of particles 15, can make between vavuum pump 10 and hollow tube 7 easier by tap hole 6Form connected state, be easy to the generation of negative pressure, thereby realize the collection of chondroconia, same, by shuntingHole 6 can make to form malleation between water jet pump 18 and hollow tube 7, thereby realizes the dilution to chondroconia.
By aperture 100-150 μ m microparticle pores 17 is set, and be communicated with passage of particles 15 by hollow tube 7,Its passage of particles 15 is connected with vavuum pump 10 and water jet pump 18, on the one hand producing in process, can pass throughHollow tube 7, to the chondroconia dilution of spraying water, in collection process, can pass through hollow tube 7 on the other handDilution particulate is collected, and size in chondroconia can be controlled within the scope of 100-150 μ m, avoidExcessive particulate affects multiplication capacity, on the basis of original passage of particles 15, has newly increased another passage,Be that chondroconia is produced and collected to hollow tube passage, can avoid particulate congestion affects in cutting head to produceThe problem of efficiency, meanwhile, also can utilize this passage from cutting head inside to concentrating on the particulate cutting headClean and block clearing, make to produce more smooth, efficiency is higher.
As the improvement of the present embodiment, the end of described Negative pressure prevention cover 2 is provided with and bores bistrique cutting head 3Conformal protective cover 20, described cutting head 3 is that protective cover 20 is exposed at smear metal position foremost, on the one hand can timeNormal smear metal cartilage, can prevent that particulate from splashing, and cuts the waste on the other hand.
As the improvement of the present embodiment, described collector is disposable box 9, described disposable box 9 and Negative pressure prevention coverBetween 2, be provided with the cassette holder 8 for being flexibly connected disposable box, described flexible connection is for being arranged on 9 mouthfuls of disposable boxesThe projection 11 of portion's outer wall and being arranged on cassette holder and the groove 12 of the mutual close-fitting of projection, described flexible connection at leastBe two, and be distributed on the surrounding of disposable box 9 and cassette holder 8. By being set, cassette holder 8 makes particulate collecting box 9Fixing reliable, convenient disassembly, arranges convex-concave structure simultaneously and is convenient to connect and processing, can improve installation effectiveness.
As the improvement of the present embodiment, also comprise the shell 13 that is arranged on motor 5 outsides, described shell appearanceFace is provided with reticulate pattern, convenient in the gripping of producing hand in process.
As the improvement of the present embodiment, on described shell, be provided with motor 5, water jet pump 18 and vavuum pump 10Gauge tap button 14, the convenient control to this device, makes to produce process accurate, avoids maloperation
As the improvement of the present embodiment, the diameter of the spherical or conical cutting head of described crusher drill is 2-5mm.
As the improvement of the present embodiment, the high 100-150 μ of described wedge shape serrated knife blade 16 m, two adjacent edge itBetween spacing be 100-150 μ m. The particulate that can make grinding produce is controlled within the scope of 100-150 μ m.
As the improvement of the present embodiment, the aperture of described microparticle pores 17 is 100-150 μ m. Can make to pass through particulateThe particulate in hole 17 is controlled within the scope of 100-150 μ m.
As the improvement of the present embodiment, the caliber of described hollow tube 7 is 150-800 μ m. Can make particle diameter beThe particulate of 100-150 μ m passes through smoothly, and difficult adhesion causes stopping up.
Finally explanation, above preferred embodiment is only unrestricted in order to technical scheme of the present invention to be described,Although the present invention is described in detail by above preferred embodiment, those skilled in the artShould be appreciated that and can make various changes to it in the form and details, and do not depart from the present inventionClaims limited range.
Claims (10)
1. chondroconia acquisition device, is characterized in that: comprise crusher drill for cutting chondroconia, collect softThe gathering system of bone particulate, drive the motor of crusher drill High Rotation Speed and be sleeved on the Negative pressure prevention on crusher drillCover, described crusher drill front end is spherical or taper cutting head, and rear end is abrasive drilling bar, and establish on described cutting head surfaceBe equipped with and be spiral-distributed wedge shape serrated knife blade, described Negative pressure prevention cover is that an end opening, the other end sealTubular structure, its blind end is provided with can be by the abrasive drilling bar mistake on abrasive drilling bar that is sleeved on of Negative pressure prevention cover sealingHole, the cutting head of its openend and crusher drill forms ring-type particulate entrance, the inner surface of described Negative pressure prevention cover,The blind end of the outer surface of abrasive drilling bar and Negative pressure prevention cover forms ring-type passage of particles, the far-end of described abrasive drilling barExtend Negative pressure prevention cover and fix with the driving shaft of motor, described gathering system comprises and is arranged on Negative pressure prevention coverOutward can to passage of particles produce the vavuum pump of absorption affinity and be communicated with passage of particles for collecting chondroconiaCollector, described gathering system also comprises the water injector that can dilute particulate, described water injector bagDraw together and be arranged on the outer water jet pump being communicated with passage of particles of Negative pressure prevention cover.
2. chondroconia acquisition device according to claim 1, is characterized in that: described wedge shape serrated knife blade itBetween and between sawtooth, be provided with multiple microparticle pores, the abrasive drilling bar of described crusher drill is hollow tube, described hollow tubeFront end be communicated with described microparticle pores, its rear end seals with plug.
3. chondroconia acquisition device according to claim 2, is characterized in that: described hollow tube is respectively veryEmpty pump and water jet pump enter to be provided with on two cross sections at entrance place of Negative pressure prevention cover and are multiplely distributed on itTap hole on circumference is communicated with passage of particles.
4. chondroconia acquisition device according to claim 1, is characterized in that: the end of described Negative pressure prevention coverPortion is provided with the protective cover conformal with boring bistrique cutting head.
5. chondroconia acquisition device according to claim 1, is characterized in that: described collector is disposable box,Between described disposable box and Negative pressure prevention cover, be provided with the cassette holder for being flexibly connected disposable box, described movable companyConnect the projection for being arranged on disposable box oral area outer wall and be arranged on cassette holder and the groove of the mutual close-fitting of projection instituteState flexible connection and be at least two, and be distributed on the surrounding of disposable box and cassette holder.
6. chondroconia acquisition device according to claim 1, is characterized in that: described crusher drill spherical orThe diameter of conical cutting head is 2-5mm.
7. chondroconia acquisition device according to claim 1, is characterized in that: described wedge shape serrated knife blade is high100-150 μ m, the spacing between two adjacent edge is 100-150 μ m.
8. chondroconia acquisition device according to claim 1, is characterized in that: the aperture of described microparticle pores is100-150μm。
9. chondroconia acquisition device according to claim 2, is characterized in that: the caliber of described hollow tube is150-800μm。
10. according to the arbitrary described chondroconia acquisition device of claim 1-9, it is characterized in that: also comprise settingAt the shell of outside motor, on described shell, be also provided with gauge tap button.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510158490.2A CN104786277B (en) | 2015-04-03 | 2015-04-03 | Chondroconia acquisition device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510158490.2A CN104786277B (en) | 2015-04-03 | 2015-04-03 | Chondroconia acquisition device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104786277A CN104786277A (en) | 2015-07-22 |
| CN104786277B true CN104786277B (en) | 2016-05-04 |
Family
ID=53551681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510158490.2A Expired - Fee Related CN104786277B (en) | 2015-04-03 | 2015-04-03 | Chondroconia acquisition device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104786277B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108096633A (en) * | 2018-01-11 | 2018-06-01 | 中国人民解放军陆军军医大学第附属医院 | A kind of cartilage defect repair material and preparation method thereof |
| CN109893301A (en) * | 2019-04-23 | 2019-06-18 | 上海市第六人民医院 | A kind of transplant and method for repairing articular cartilage defect |
| CN112545577A (en) * | 2020-12-10 | 2021-03-26 | 咸宁市中心医院 | Biopsy device for windowing bone tumor or bone disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070293867A1 (en) * | 2004-02-05 | 2007-12-20 | Bti,I+D, S.L. | Method and Tools for Low-Speed Milling Without Irrigation and with Extraction and Recovery of Tissue Particles |
| CN101496913B (en) * | 2008-01-31 | 2012-09-26 | 中国人民解放军总医院 | Cartilage cell epimatrix three-dimensional porous sponge stent for tissue engineering and preparation method thereof |
| KR101056069B1 (en) * | 2008-10-13 | 2011-08-10 | 아주대학교산학협력단 | Method for producing porous three-dimensional scaffold using animal tissue powder |
| CN203370139U (en) * | 2013-07-26 | 2014-01-01 | 中国人民解放军第三军医大学第一附属医院 | Injectable tissue engineering cartilage in-vitro construction device |
-
2015
- 2015-04-03 CN CN201510158490.2A patent/CN104786277B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN104786277A (en) | 2015-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN204562293U (en) | Chondroconia acquisition device | |
| CN104161562B (en) | Minimally invasive bone fetcher | |
| CN104786277B (en) | Chondroconia acquisition device | |
| CN100534394C (en) | Facial bone contouring device using hollowed rasp provided with non-plugging holes formed through cutting plane | |
| CN203935241U (en) | Micro-wound bone taking device | |
| CN101744652B (en) | Multifunctional prostate operation mirror | |
| US11622777B2 (en) | Tissue trap for chondral autograft transfer system | |
| CN1218380A (en) | Method and system for performing cataract surgery | |
| JP2004170414A (en) | Tissue biopsy / processing device and method therefor | |
| CN110339919B (en) | Raw materials reducing mechanism for mechanized production | |
| CN104887292A (en) | System and method of bone processing | |
| CN103767758B (en) | A kind of composite medical osteoclast and application thereof | |
| CN101828943A (en) | Ultrasonic orthopedic surgery saw | |
| CN108702883A (en) | Multifunction soil disintegrating apparatus | |
| CN103767757B (en) | Specific complex osteoclast and application thereof in spinal surgery art | |
| CN2469895Y (en) | Sneak-dilating decompressor for head of femur | |
| CN110249729A (en) | Full-automatic transplantation combine rotary tillage ditching system | |
| CN110090058A (en) | The saw device for excising of interverbebral disc under a kind of adjustable type backbone scope | |
| CN205292995U (en) | Water hyacinth harvesting ship | |
| CN215683408U (en) | Weed trimming means of nursery stock planting usefulness | |
| CN203693687U (en) | Special composite bone crusher for spine surgery | |
| CN209018854U (en) | Bone chopper for spinal surgery | |
| KR102541045B1 (en) | Cartilage collecting device | |
| CN210931655U (en) | Bone file for removing articular surface cartilage | |
| CN210700457U (en) | Fat cutter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160504 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |