CN104784277A - Acne-removing essence - Google Patents

Abstract

The invention relates to an acne-removing essence. The acne-removing essence comprises the following components in percentage by weight: 3-20% of a salvia miltiorrhiza extract, 2-15% of a radix sophorae flavescentis extract, 1-15% of a polygonum cuspidatum extract, 0.5-10% of a coptis chinensis extract, 0.5-1% of a folium eriobotryae extract, 0.5-5% of a radix scutellariae extract, 0.5-10% of a cortex mori radicis extract, 1.5-10% of raw gypsum, 0.5-5% of medical stone and 40-90% of deionized water. The acne-removing essence is capable of firstly detoxifying, then removing acne, shrinking pores, activating skin cells and tendering skin, so that the magical effect of treating both symptoms and root causes is achieved; the skin metabolism is accelerated by detoxifying; more importantly, the acne-removing essence is free of additives such as alcohols and antibacterial components; the acne-removing essence is prepared from pure natural traditional Chinese medicine components, is suitable for sensitive skin and can be widely popularized and applied.

Description

One removes acne essence

Technical field

The invention belongs to the technical field of medicine, specifically relate to one and remove acne essence.

Background technology

Acne is that one is mainly in teen-age chronic skin inflammation, as improper in treated not in time or preventing and treating, and can leave over the cicatrix that lifelong difficulty heals, thus affect appearance, makes numerous adolescent patients very worried.Externally applied product at present on the market for acne of dispelling is many containing Azelaic Acid, cimetidine, benzoyl peroxide, adapalene, Viaminate etc., also has the external preparation that some Tri-Biocins are made, mainly secreted by oil-control, accelerate the Acne treatment that comes off of epidermal keratinocytes, skin easily irritated, rubescent, decortication after this series products of use, drug withdrawal is easily recurred, form a kind of drug dependence, and in most externally applied product, all containing hormone and other harmful chemical components such as hydrargyrum, lead, anti-acne is temporary transient.Therefore, what now commercially occurred Chinese medicine ingredients removes acne preparation, but it all with the addition of alcohols and anti-microbial type auxiliary agent, easily produces skin allergy, is not suitable for sensitivity crowd, cannot apply widely.Therefore, the present invention is proposed.

Summary of the invention

For solving the above-mentioned technical problem of prior art, the object of this invention is to provide one and remove acne essence, first toxin expelling, then anti-acne, pore refining, activating skin cells, fine skin, reach the magical effect for the treatment of both the principal and secondary aspects of a disease, promote skin metabolism by toxin expelling, what is more important, this goes acne essence not add the auxiliary agent such as alcohols, anti-microbial type, adopt the Chinese medicine ingredients of pure natural, can sensitive skin be applicable to, can be applicable widely.

For achieving the above object, the present invention is achieved by the following technical solutions:

One removes acne essence, composed of the following components: Radix Salviae Miltiorrhizae extract, Radix Sophorae Flavescentis extract, Rhizoma Polygoni Cuspidati extract, Rhizoma Coptidis extract, Folium Eriobotryae fermented product, Radix Scutellariae extract, Cortex Mori extract, Gypsum Fibrosum, Maifanitum and deionized water.

Described removes acne essence, composed of the following components by weight percentage:

Radix Salviae Miltiorrhizae extract 3-20%

Radix Sophorae Flavescentis extract 2-15%

Rhizoma Polygoni Cuspidati extract 1-15%

Rhizoma Coptidis extract 0.5-10%

Folium Eriobotryae fermented product 0.5-1%

Radix Scutellariae extract 0.5-5%

Cortex Mori extract 0.5-10%

Gypsum Fibrosum 1.5-10%

Maifanitum 0.5-5%

Deionized water 40-90%.

The described preparation method of acne essence of going is:

(1) by Radix Salviae Miltiorrhizae extract, Radix Sophorae Flavescentis extract, Rhizoma Coptidis extract, Rhizoma Polygoni Cuspidati extract, Folium Eriobotryae fermented product, Radix Scutellariae extract and Cortex Mori extract respectively dry, be crushed to 5-80 order, obtain coarse powder;

(2) step (1) gained coarse powder is loaded in supercritical extraction reactor, add Gypsum Fibrosum, deionized water and Maifanitum, adopt CO ₂supercritical fluid extraction, extraction temperature is 25-45 DEG C, extracting pressure 15-55Mpa, and extraction time is 2-5 hour, CO ₂flow velocity is 8-22L/h; Obtain supercritical CO containing extract ₂fluid, be separated by decantation to extraction product, separation temperature 25-45 DEG C through decompression solution, separating pressure is 15-55Mpa, collects volatile effective component and fat-soluble effective ingredient, obtains acne essence;

Described Rhizoma Polygoni Cuspidati extract is obtained by following methods: spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry, aseptically utilize machinery to make pulping; Then add the rear centrifugalize of purified water dilution, remove slag, obtain gluey extracting solution; Gluey extracting solution is oven drying at low temperature spraying after lyophilization process, takes out, be cooled to room temperature state when being 8% through 60 degree of oven drying at low temperatures to water content, crosses 100-200 mesh sieve.

Beneficial effect of the present invention is as follows:

The acne essence that goes of the present invention extracts to be composited from pure natural plant, not containing any spice and chemical adding ingredient, and first toxin expelling, anti-acne again, pore refining, activating skin cells, fine skin, reach the magical effect for the treatment of both the principal and secondary aspects of a disease, promote skin metabolism by toxin expelling.What is more important, this goes acne essence not add the auxiliary agent such as alcohols, anti-microbial type, adopts the Chinese medicine ingredients of pure natural, can be applicable to sensitive skin, can be applicable widely.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further illustrated, but protection scope of the present invention is not limited to this.

The raw material Radix Salviae Miltiorrhizae extract that the present invention adopts, Radix Sophorae Flavescentis extract, Rhizoma Polygoni Cuspidati extract, Rhizoma Coptidis extract, Folium Eriobotryae fermented product, Radix Scutellariae extract, Cortex Mori extract, Gypsum Fibrosum, Maifanitum and deionized water all can adopt conventional method to obtain, and also can adopt commercially available prod.

embodiment 1

The preparation method of acne essence of going of the present embodiment 1 is:

(1) by Radix Salviae Miltiorrhizae extract 3%, Radix Sophorae Flavescentis extract 2%, Rhizoma Coptidis extract 0.5%, Rhizoma Polygoni Cuspidati extract 1%, Folium Eriobotryae fermented product 0.5%, Radix Scutellariae extract 0.5% and Cortex Mori extract 0.5% respectively dry, be crushed to 5 orders, obtain coarse powder;

(2) step (1) gained coarse powder is loaded in supercritical extraction reactor, add Gypsum Fibrosum 1.5%, deionized water 90% and Maifanitum 0.5%, adopt CO ₂supercritical fluid extraction, extraction temperature is 25 DEG C, extracting pressure 15Mpa, and extraction time is 2 hours, CO ₂flow velocity is 8L/h; Obtain supercritical CO containing extract ₂fluid, be separated by decantation to extraction product, separation temperature 25 DEG C through decompression solution, separating pressure is 15Mpa, collects volatile effective component and fat-soluble effective ingredient, obtains acne essence;

Rhizoma Polygoni Cuspidati extract in the present embodiment 1 is obtained by following methods: spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry, aseptically utilize machinery to make pulping; Then add the rear centrifugalize of purified water dilution, remove slag, obtain gluey extracting solution; Gluey extracting solution is oven drying at low temperature spraying after lyophilization process, takes out, be cooled to room temperature state when being 8% through 60 degree of oven drying at low temperatures to water content, crosses 100 mesh sieves.

embodiment 2

The preparation method of acne essence of going of the present embodiment 2 is:

(1) by Radix Salviae Miltiorrhizae extract 5%, Radix Sophorae Flavescentis extract 3%, Rhizoma Coptidis extract 10%, Rhizoma Polygoni Cuspidati extract 1%, Folium Eriobotryae fermented product 1%, Radix Scutellariae extract 5% and Cortex Mori extract 10% respectively dry, be crushed to 80 orders, obtain coarse powder;

(2) step (1) gained coarse powder is loaded in supercritical extraction reactor, add Gypsum Fibrosum 10%, deionized water 50% and Maifanitum 5%, adopt CO ₂supercritical fluid extraction, extraction temperature is 45 DEG C, extracting pressure 55Mpa, and extraction time is 5 hours, CO ₂flow velocity is 22L/h; Obtain supercritical CO containing extract ₂fluid, be separated by decantation to extraction product, separation temperature 45 DEG C through decompression solution, separating pressure is 55Mpa, collects volatile effective component and fat-soluble effective ingredient, obtains acne essence;

The Rhizoma Polygoni Cuspidati extract of the present embodiment 2 is obtained by following methods: spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry, aseptically utilize machinery to make pulping; Then add the rear centrifugalize of purified water dilution, remove slag, obtain gluey extracting solution; Gluey extracting solution is oven drying at low temperature spraying after lyophilization process, takes out, be cooled to room temperature state when being 8% through 60 degree of oven drying at low temperatures to water content, crosses 200 mesh sieves.

embodiment 3

The preparation method of acne essence of going of the present embodiment 3 is:

(1) by Radix Salviae Miltiorrhizae extract 20%, Radix Sophorae Flavescentis extract 15%, Rhizoma Coptidis extract 1%, Rhizoma Polygoni Cuspidati extract 10%, Folium Eriobotryae fermented product 0.8%, Radix Scutellariae extract 0.8% and Cortex Mori extract 5% respectively dry, be crushed to 42 orders, obtain coarse powder;

(2) step (1) gained coarse powder is loaded in supercritical extraction reactor, add Gypsum Fibrosum 1.5%, deionized water 45% and Maifanitum 0.9%, adopt CO ₂supercritical fluid extraction, extraction temperature is 35 DEG C, extracting pressure 35Mpa, and extraction time is 3.5 hours, CO ₂flow velocity is 15L/h; Obtain supercritical CO containing extract ₂fluid, be separated by decantation to extraction product, separation temperature 35 DEG C through decompression solution, separating pressure is 35Mpa, collects volatile effective component and fat-soluble effective ingredient, obtains acne essence;

Rhizoma Polygoni Cuspidati extract in the present embodiment 3 is obtained by following methods: spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry, aseptically utilize machinery to make pulping; Then add the rear centrifugalize of purified water dilution, remove slag, obtain gluey extracting solution; Gluey extracting solution is oven drying at low temperature spraying after lyophilization process, takes out, be cooled to room temperature state when being 8% through 60 degree of oven drying at low temperatures to water content, crosses 150 mesh sieves.

embodiment 4

The preparation method of acne essence of going of the present embodiment 4 is:

(1) by Radix Salviae Miltiorrhizae extract 11.5%, Radix Sophorae Flavescentis extract 8.5%, Rhizoma Coptidis extract 0.5%, Rhizoma Polygoni Cuspidati extract 8%, Folium Eriobotryae fermented product 0.5%, Radix Scutellariae extract 0.5% and Cortex Mori extract 1.0% respectively dry, be crushed to 25 orders, obtain coarse powder;

(2) step (1) gained coarse powder is loaded in supercritical extraction reactor, add Gypsum Fibrosum 1.5%, deionized water 67.5% and Maifanitum 0.5%, adopt CO ₂supercritical fluid extraction, extraction temperature is 40 DEG C, extracting pressure 28Mpa, and extraction time is 4 hours, CO ₂flow velocity is 12L/h; Obtain supercritical CO containing extract ₂fluid, be separated by decantation to extraction product, separation temperature 30 DEG C through decompression solution, separating pressure is 40Mpa, collects volatile effective component and fat-soluble effective ingredient, obtains acne essence;

Rhizoma Polygoni Cuspidati extract in the present embodiment 4 is obtained by following methods: spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry, aseptically utilize machinery to make pulping; Then add the rear centrifugalize of purified water dilution, remove slag, obtain gluey extracting solution; Gluey extracting solution is oven drying at low temperature spraying after lyophilization process, takes out, be cooled to room temperature state when being 8% through 60 degree of oven drying at low temperatures to water content, crosses 180 mesh sieves.

application examples

In order to show the therapeutic effect of acne preparation of dispelling of the present invention, elite case of selecting the Cuo patient that dispels of all ages and classes different sexes, utilize acne preparation of dispelling of the present invention to treat, a course for the treatment of is 30 days.

The therapeutic effect of the acne preparation of dispelling that table 1 obtains for embodiment 1:

Table 1

The therapeutic effect of the acne preparation of dispelling that table 2 obtains for embodiment 2:

Table 2

The therapeutic effect of the acne preparation of dispelling that table 3 obtains for embodiment 3:

Table 3

The therapeutic effect of the acne preparation of dispelling that table 4 obtains for embodiment 4:

Table 4

From table 1-table 4, the acne essence that goes of the present invention extracts to be composited from pure natural plant, not containing any spice and chemical adding ingredient, first toxin expelling, then anti-acne, pore refining, activating skin cells, fine skin, reach the magical effect for the treatment of both the principal and secondary aspects of a disease, promote skin metabolism by toxin expelling.What is more important, this goes acne essence not add the auxiliary agent such as alcohols, anti-microbial type, adopts the Chinese medicine ingredients of pure natural, can be applicable to sensitive skin, can be applicable widely.

Above-described embodiment only illustrates inventive concept of the present invention for explaining, but not the restriction to rights protection of the present invention, all changes utilizing this design the present invention to be carried out to unsubstantiality, all should fall into protection scope of the present invention.

Claims (3)

1. remove an acne essence, it is characterized in that composed of the following components: Radix Salviae Miltiorrhizae extract, Radix Sophorae Flavescentis extract, Rhizoma Polygoni Cuspidati extract, Rhizoma Coptidis extract, Folium Eriobotryae fermented product, Radix Scutellariae extract, Cortex Mori extract, Gypsum Fibrosum, Maifanitum and deionized water.

2. remove acne essence as claimed in claim 1, it is characterized in that composed of the following components by weight percentage:

Radix Salviae Miltiorrhizae extract 3-20%

Radix Sophorae Flavescentis extract 2-15%

Rhizoma Polygoni Cuspidati extract 1-15%

Rhizoma Coptidis extract 0.5-10%

Folium Eriobotryae fermented product 0.5-1%

Radix Scutellariae extract 0.5-5%

Cortex Mori extract 0.5-10%

Gypsum Fibrosum 1.5-10%

Maifanitum 0.5-5%

Deionized water 40-90%.

3. remove acne essence as claimed in claim 1 or 2, described in it is characterized in that, go the preparation method of acne essence to be:

(1) by Radix Salviae Miltiorrhizae extract, Radix Sophorae Flavescentis extract, Rhizoma Coptidis extract, Rhizoma Polygoni Cuspidati extract, Folium Eriobotryae fermented product, Radix Scutellariae extract and Cortex Mori extract respectively dry, be crushed to 5-80 order, obtain coarse powder;

(2) step (1) gained coarse powder is loaded in supercritical extraction reactor, add Gypsum Fibrosum, deionized water and Maifanitum, adopt CO ₂supercritical fluid extraction, extraction temperature is 25-45 DEG C, extracting pressure 15-55Mpa, and extraction time is 2-5 hour, CO ₂flow velocity is 8-22L/h; Obtain supercritical CO containing extract ₂fluid, be separated by decantation to extraction product, separation temperature 25-45 DEG C through decompression solution, separating pressure is 15-55Mpa, collects volatile effective component and fat-soluble effective ingredient, obtains acne essence;

Described Rhizoma Polygoni Cuspidati extract is obtained by following methods: spring, Qiu Erji excavate, and removing fibrous root, cleans, take advantage of short section of fresh-cut or sheet, dry, aseptically utilize machinery to make pulping; Then add the rear centrifugalize of purified water dilution, remove slag, obtain gluey extracting solution; Gluey extracting solution is oven drying at low temperature spraying after lyophilization process, takes out, be cooled to room temperature state when being 8% through 60 degree of oven drying at low temperatures to water content, crosses 100-200 mesh sieve.