CN104783778B - The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals - Google Patents

The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals Download PDF

Info

Publication number
CN104783778B
CN104783778B CN201510197734.8A CN201510197734A CN104783778B CN 104783778 B CN104783778 B CN 104783778B CN 201510197734 A CN201510197734 A CN 201510197734A CN 104783778 B CN104783778 B CN 104783778B
Authority
CN
China
Prior art keywords
signal
signals
square wave
single channel
resistance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201510197734.8A
Other languages
Chinese (zh)
Other versions
CN104783778A (en
Inventor
李刚
宋韶秀
杨悦
易小清
林凌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin University
Original Assignee
Tianjin University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin University filed Critical Tianjin University
Priority to CN201510197734.8A priority Critical patent/CN104783778B/en
Publication of CN104783778A publication Critical patent/CN104783778A/en
Application granted granted Critical
Publication of CN104783778B publication Critical patent/CN104783778B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/398Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

The invention discloses a kind of biological electricity and the single channel harvester and method of quadrature square wave modulation multiple signals, the harvester gathers N roads biomedicine signals via analog-digital converter all the way, including is loaded with the high frequency quadrature square wave and low frequency bioelectrical signals of PPG signals.Current signal is converted into default amplitude voltage signal through current/voltage-converted amplifier, default amplitude bioelectrical signals are obtained by bioelectrical signals detection circuit, default amplitude voltage signal obtains mixed signal with default amplitude bioelectrical signals after adder operation circuit is added, mixed signal is converted into data signal by single channel analog-digital converter, microprocessor is handled data signal, modulation orthogonal square-wave signal and low frequency bioelectrical signals are isolated, and multichannel PPG signals are demodulated from modulation orthogonal square-wave signal.The characteristics of present invention realizes synchronizes collection to multichannel biomedicine signals via single channel analog-digital converter, and simple with circuit, and cost is cheap and measurement is accurate.

Description

The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals
Technical field
The present invention relates to Biomedical Signals Acquisition field, more particularly to a kind of biological electricity and quadrature square wave modulation multichannel letter Number single channel harvester and method.
Background technology
The variable quantity of the carrying informations such as voltage signal, is represented in an analogue form in its relaxed state, still, in order to It is easy to computer disposal, transmission and storage, data signal is generally transformed into by analog-digital converter, therefore cure in biology Learn in signal transacting, analog-to-digital conversion is essential.
Inventor has found during the present invention is realized, in existing multichannel Biomedical Signals Acquisition, need to generally adopt With multi-disc ADC or multiway analog switch collocation monolithic ADC scheme, the former has, and circuit is complicated, system power dissipation height and circuit chi The shortcomings that very little big;And the latter then can be in gatherer process, due to the switching of variable connector, insertion switch noise, and due to more There is settling time in way switch, can cause to interfere between adjacent channel signals.
The content of the invention
The invention provides a kind of biological electricity and the single channel harvester and method of quadrature square wave modulation multiple signals, this hair It is bright that analog-to-digital conversion is realized to multichannel biomedicine signals by single channel analog-digital converter, it is described below:
The single channel harvester of a kind of biological electricity and quadrature square wave modulation multiple signals, the single channel harvester include: Microprocessor, the quadrature square wave of the microprocessor output different frequency, quadrature square wave drive at least two kinds of light emitting diodes, hair The light that optical diode is sent is received after tested finger by light-sensitive device, and the light-sensitive device is converted into current signal, electric current letter Number it is converted into default amplitude voltage signal through current/voltage-converted amplifier;
The single channel harvester also includes:Low frequency bioelectrical signals detection circuit, adder operation circuit and single channel mould Number converter;
The low frequency bioelectrical signals detection circuit obtains default amplitude bioelectrical signals, the default amplitude voltage signal Mixed signal is obtained after the adder operation circuit is added with the default amplitude bioelectrical signals, the mixed signal is by institute State single channel analog-digital converter and be converted into data signal;
The microprocessor is handled data signal, isolates modulation orthogonal square-wave signal and low frequency biology telecommunications Number, and multichannel PPG signals are demodulated from modulation orthogonal square-wave signal.
Wherein, the low frequency bioelectrical signals are specially:Any one in ECG, EEG, EMG, EGG and EOG.
Wherein, the adder operation circuit includes:First resistor and second resistance, one end access the of the first resistor One signal source, one end access secondary signal source of the second resistance, the other end of the first resistor and the second resistance Another termination operational amplifier negative polarity input;One end of positive polarity input the 4th resistance of termination of operational amplifier, The other end ground connection of 4th resistance;The negative polarity input of the operational amplifier also accesses the one of 3rd resistor simultaneously End, the output end of another termination operational amplifier of the 3rd resistor, output signal voltage.
Another embodiment, the adder operation circuit include:First resistor and second resistance, one end of the first resistor Access the first signal source, one end access secondary signal source of the second resistance, the other end of the first resistor and described the The positive polarity input of another termination operational amplifier of two resistance;The negative polarity input of the operational amplifier connects the simultaneously One end of three resistance and the 4th resistance;The other end ground connection of 4th resistance;Another termination computing of the 3rd resistor is put The output end of big device, output signal voltage.
A kind of acquisition method for biological electricity and the single channel harvester of quadrature square wave modulation multiple signals, methods described Comprise the following steps:
Mixed signal is converted into data signal by single channel analog-digital converter and is sent into microprocessor;
Microprocessor carries out low-pass filtering treatment to data signal and recovers low frequency bioelectrical signals;Microprocessor is to numeral Signal carries out separating treatment and obtains PPG signals and bioelectrical signals, and the bias light interference in PPG signals is eliminated;
The valley and peak value of PPG signals are calculated respectively;Again as corresponding to each wavelength of valley and peak computational of PPG signals Absorbance difference Δ A, the spectral value being made up of absorbance difference Δ A can be obtained.
Wherein, the microprocessor carries out separating treatment to data signal and obtains PPG signals and bioelectrical signals, and PPG Bias light interference the step of being eliminated in signal is specially:
Assuming that the quadrature square wave signal frequency of microprocessor output driving light emitting diode 2 be respectively 2 times of f, 2 times of f, 1 times F, 1 times of f, wherein same frequency square wave phase differ 90 °, and the sample frequency of single channel analog-digital converter is fs, and fs=8f, and protect Demonstrate,prove the high and low level intermediate samples in most high-frequency driving signal;
Quadrature square wave signal low and high level sampled point number is n, and is the complete cycle of lowest frequency signal;N is asked for respectively The voltage magnitude sum of individual high level sampled point, the voltage magnitude sum of n low level sampled point, obtain two voltage magnitudes it The difference of sum;The difference is n times of PPG signals;The interference of bias light and low frequency bioelectrical signals is eliminated, obtains multichannel PPG letters Number.
The beneficial effect of technical scheme provided by the invention is:The present invention is cured by single channel analog-digital converter to multichannel biology Learn signal and realize analog-to-digital conversion, and it is simple with circuit, cost is cheap and measures the advantages of accurate;And when using design During adder operation circuit, in that context it may be convenient to get the high mixed frequency signal of stabilization, precision, being easily integrated, and reduce circuit Cost, the dynamic range of signal is expanded, meet a variety of needs in practical application.
Brief description of the drawings
Fig. 1 is a kind of structural representation for the single channel harvester that biological electricity modulates multiple signals with quadrature square wave;
Fig. 2 is the structural representation of adder operation circuit;
Fig. 3 is another structural representation of adder operation circuit;
Fig. 4 is the schematic diagram of separation different wave length PPG signals provided by the invention;
Fig. 5 is a kind of flow chart for the single channel acquisition method that biological electricity modulates multiple signals with quadrature square wave.
In accompanying drawing, the list of parts representated by each label is as follows:
1:Microprocessor; 2:Light emitting diode;
3:Light-sensitive device; 4:Current/voltage-converted amplifier;
5:Low frequency bioelectrical signals detect circuit; 6:Adder operation circuit;
7:Single channel analog-digital converter.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention is made below further It is described in detail on ground.
Embodiment 1
The single channel harvester of a kind of biological electricity and quadrature square wave modulation multiple signals, referring to Fig. 1, the single channel harvester Including:Microprocessor 1, at least two kinds of light emitting diodes 2, light-sensitive device 3, current/voltage-converted amplifier 4, low frequency biology telecommunications Number detection circuit 5, adder operation circuit 6 and single channel analog-digital converter 7,
The quadrature square wave of the output different frequency of microprocessor 1, at least two kinds of light emitting diodes 2 of quadrature square wave driving, luminous two The light that pole pipe 2 is sent is received after tested finger by light-sensitive device 3, and light-sensitive device 3 is converted into current signal, and current signal is through electricity Stream/voltage converting amplifiers 4 are converted into default amplitude voltage signal.
Low frequency bioelectrical signals detect circuit 5 and obtain default amplitude bioelectrical signals, preset amplitude voltage signal with presetting Amplitude bioelectrical signals obtain mixed signal after the addition of adder operation circuit 6, and mixed signal is changed by single channel analog-digital converter 7 Into data signal, microprocessor 1 is handled data signal, isolates modulation orthogonal square-wave signal and low frequency biology telecommunications Number, and PPG signals are demodulated from modulation orthogonal square-wave signal.
Wherein, the quantity of light emitting diode 2 is more than or equal to 2.During specific implementation, the quantity of light emitting diode 2 is according to reality Needs in are set;The amplitude of default amplitude voltage signal and default amplitude bioelectrical signals is according in practical application Needs set, during specific implementation, the embodiment of the present invention is without limitation.
Wherein, low frequency bioelectrical signals include:Any one in the bioelectrical signals such as ECG, EEG, EMG, EGG, EOG. Microprocessor 1 can use any one in MCU, ARM, DSP or FPGA.Adder operation circuit 6 is using routine on the market Addition device.
Wherein, the gain of bioelectrical signals detection circuit 5 and bandwidth are by the amplitude and frequency of the bioelectrical signals detected Scope determines.
Embodiment 2
The single channel harvester of a kind of biological electricity and quadrature square wave modulation multiple signals, referring to Fig. 1, the single channel harvester Including:Microprocessor 1, at least two kinds of light emitting diodes 2, light-sensitive device 3, current/voltage-converted amplifier 4, low frequency biology telecommunications Number detection circuit 5, adder operation circuit 6 and single channel analog-digital converter 7.The embodiment as different from Example 1, the addition The adder operation circuit 6 that computing circuit 6 is designed using the embodiment of the present invention realizes that, referring to Fig. 2, the adder operation circuit 6 wraps Include:First resistor R1With second resistance R2,
First resistor R1One end access the first signal source V1, second resistance R2One end access secondary signal source V2, first Resistance R1The other end and second resistance R2Another termination operational amplifier A negative polarity input;Operational amplifier A is just The 4th resistance R of polarity input termination4One end, the 4th resistance R4The other end ground connection;The negative polarity input of operational amplifier A Also access 3rd resistor R simultaneously3One end, 3rd resistor R3Another termination operational amplifier A output end, output signal electricity Press Vo.
First signal source V1, secondary signal source V2Respectively default amplitude voltage signal and default amplitude bioelectrical signals; Or, the first signal source V1, secondary signal source V2Respectively default amplitude bioelectrical signals and default amplitude voltage signal;Signal electricity Pressure Vo is mixed signal.
Embodiment 3
The single channel harvester of a kind of biological electricity and quadrature square wave modulation multiple signals, referring to Fig. 1, the single channel harvester Including:Microprocessor 1, at least two kinds of light emitting diodes 2, light-sensitive device 3, current/voltage-converted amplifier 4, low frequency biology telecommunications Number detection circuit 5, adder operation circuit 6 and single channel analog-digital converter 7.The embodiment as different from Example 1, the addition Computing circuit 6 can be realized using the adder operation circuit 6 that the embodiment of the present invention designs, referring to Fig. 3, the adder operation circuit 6 include:First resistor R1With second resistance R2,
First resistor R1One end access the first signal source V1, second resistance R2One end access secondary signal source V2, first Resistance R1The other end and second resistance R2Another termination operational amplifier A positive polarity input;Operational amplifier A is born Polarity input meets 3rd resistor R simultaneously3With the 4th resistance R4One end;4th resistance R4The other end ground connection;3rd resistor R3 Another termination operational amplifier A output end, output signal voltage Vo.
First signal source V1, secondary signal source V2Respectively default amplitude voltage signal and default amplitude bioelectrical signals; Or, the first signal source V1, secondary signal source V2Respectively default amplitude bioelectrical signals and default amplitude voltage signal;Signal electricity Pressure Vo is mixed signal.
Embodiment 4
The single channel acquisition method of a kind of biological electricity and quadrature square wave modulation multiple signals, referring to Fig. 4 and Fig. 5, this method bag Include following steps:
101:Mixed signal is converted into data signal by single channel analog-digital converter 7 and is sent into microprocessor 1;
102:Microprocessor 1 carries out low-pass filtering treatment to data signal and recovers low frequency bioelectrical signals;Microprocessor 1 Separating treatment is carried out to data signal and obtains PPG signals and bioelectrical signals, and the bias light interference in PPG signals is eliminated;
Wherein, the step is specially:
1) the quadrature square wave signal frequency for assuming the output driving light emitting diode 2 of microprocessor 1 is respectively 2 times of f, 2 times of f, 1 Times f, 1 times of f, wherein same frequency square wave phase differ 90 °, and the sample frequency of single channel analog-digital converter 7 is fs, and fs=8f, and Ensure in the high and low level intermediate samples of most high frequency (2f) drive signal;
2) quadrature square wave signal low and high level sampled point number is n, and is the complete cycle of lowest frequency (1f) signal, respectively Voltage magnitude sum, the voltage magnitude sum of n low level sampled point of n high level sampled point are asked for, obtains two voltages The difference of amplitude sum;The difference is n times of PPG signals (corresponding with the wavelength of quadrature square wave);Eliminate bias light and low frequency The interference of bioelectrical signals, obtain multichannel PPG signals.
Illustrated for the sake of concise explanation by taking the light emitting diode 2 of 4 kinds of wavelength as an example, it is assumed that λ 1 (D1 light emitting diodes) It is 2 times of f, λ 3 (D3 light emitting diodes) and λ to drive quadrature square wave frequency with the light emitting diode 2 of λ 2 (D2 light emitting diodes) wavelength It is respectively 1 times of f that the light emitting diode 2 of 4 (D4 light emitting diodes) wavelength, which drives quadrature square wave frequency, and λ 1, the hair of the wavelength of λ 2 The driving quadrature square wave frequency of optical diode 2 is identical but phase differs 90 °, λ 3, the wavelength of λ 4 light emitting diode 2 driving it is orthogonal Square wave frequency is identical but phase differs 90 °.
It is assumed that the sample frequency of single analog converter 7 is fS, and fS=8f, and ensure in the high and low level of the drive signals of λ 1 Intermediate samples.
Digital signal sequencesIt can be expressed as:
Wherein,WithRespectively wavelength X 1, λ 2, λ 3 and λ 4 PPG signals,Believe for low frequency Number, including:Low frequency bioelectrical signals, bias light, the dark current of light-sensitive device 3, the imbalance electricity of current/voltage-converted amplifier 4 Pressure.
It is assumed that sample frequency fSFar above modulation orthogonal square-wave signal and the change frequency of low frequency signal, in minimum driving letter The a cycle of number frequency can be approximately considered each road quadrature square wave signal amplitude and low frequency signal amplitude it is constant.Before most Exemplified by 8 sampled datas:
Wherein,WithRespectively wavelength X 1, λ 2, λ 3 and λ 4 optical signal and background letter Number amplitude.
In other words, using every 8 data signals of order as one group of carry out computing:
Obtain the optical signal of 4 times of wavelength X 1And completely eliminate low frequency signalInfluence.
Obtain the optical signal of 4 times of wavelength X 2And completely eliminate background signalInfluence.
Obtain the optical signal of 4 times of wavelength X 3And completely eliminate background signalInfluence.
Obtain the optical signal of 4 times of wavelength X 4And completely eliminate background signalInfluence.
103:The valley and peak value of PPG signals are calculated respectively;Again by each wavelength institute of valley and peak computational of PPG signals Corresponding absorbance difference Δ A, can be obtained by Δ Aλ1、ΔAλ2……ΔAλnThe spectral value of composition.
Due to the pulsation phenomenon of artery, it is in cyclically-varying to make CBF in blood vessel, and blood is height opaque liquid, Therefore the change of pulse beating necessarily causes the change of absorbance.
Consider arteries fullness degree minimum state, the incident light from light source not by pulsatile arterial blood absorption, this When output intensity ImaxIt is most strong, it can be considered the incident light I of pulsatile arterial blood;And arteries fullness degree highest state is corresponding At the time of the effect of the valley point of photoelectric sphyg ripple, i.e. pulsatile arterial blood is maximum, output intensity I nowminIt is most weak, it is dynamic to pulse The minimum output intensity I of arteries and veins blood.So filled by recording artery to the maximum absorbance with during arterial contraction to minimum Value, it is possible to which eliminating skin histology, hypodermis etc., all have shadow of the human body component for absorbance of constant absorption feature Ring.
If incident intensity is I0, it is respectively I to detect light intensity when light intensity and arterial contraction are detected when artery is fullminAnd Imax, Absorbance difference during absorbance and arterial contraction when then artery is full is:
Measure the valley I of each photoplethysmographicminAnd peak ImaxIt can obtain corresponding to photoplethysmographic Absorbance difference Δ A, can obtain by Δ Aλ1、ΔAλ2……ΔAλnThe spectral value of composition.
That is, the valley and peak value of wavelength X 1, λ 2, λ 3 and λ 4 PPG signals are calculated respectively:Iminλ1、Imaxλ1、Iminλ2、 Imaxλ2、Iminλ3、Imaxλ3、Iminλ4And Imaxλ4
To the model of each device in addition to specified otherwise is done, the model of other devices is not limited the embodiment of the present invention, As long as the device of above-mentioned function can be completed.
It will be appreciated by those skilled in the art that accompanying drawing is the schematic diagram of a preferred embodiment, the embodiments of the present invention Sequence number is for illustration only, does not represent the quality of embodiment.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and Within principle, any modification, equivalent substitution and improvements made etc., it should be included in the scope of the protection.

Claims (5)

1. the single channel harvester of a kind of biological electricity and quadrature square wave modulation multiple signals, the single channel harvester include:It is micro- Processor, the quadrature square wave of the microprocessor output different frequency, quadrature square wave drive at least two kinds of light emitting diodes, lighted The light that diode is sent is received after tested finger by light-sensitive device, and the light-sensitive device is converted into current signal, current signal Default amplitude voltage signal is converted into through current/voltage-converted amplifier;Characterized in that,
The single channel harvester also includes:Low frequency bioelectrical signals detection circuit, adder operation circuit and single channel modulus turn Parallel operation;
The low frequency bioelectrical signals detection circuit obtains default amplitude bioelectrical signals, the default amplitude voltage signal and institute State default amplitude bioelectrical signals and obtain mixed signal after adder operation circuit addition, the mixed signal is by the list Road analog-digital converter is converted into data signal;
The microprocessor is handled data signal, isolates modulation orthogonal square-wave signal and low frequency bioelectrical signals, and Multichannel PPG signals are demodulated from modulation orthogonal square-wave signal;
The quadrature square wave signal frequency of microprocessor output driving light emitting diode is respectively 2 times of f, 2 times of f, 1 times of f, 1 times of f, its The phase of middle same frequency square wave differs 90 °, and the sample frequency of single channel analog-digital converter is fs, and fs=8f, and ensure in most high frequency The high and low level intermediate samples of drive signal;
Quadrature square wave signal low and high level sampled point number is n, and is the complete cycle of lowest frequency signal;Ask for respectively n high The voltage magnitude sum of level sampling point, the voltage magnitude sum of n low level sampled point, obtain two voltage magnitude sums Difference;The difference is n times of PPG signals;The interference of bias light and low frequency bioelectrical signals is eliminated, obtains multichannel PPG signals.
2. the single channel harvester of a kind of biological electricity according to claim 1 and quadrature square wave modulation multiple signals, it is special Sign is that the low frequency bioelectrical signals are specially:Any one in ECG, EEG, EMG, EGG and EOG.
3. the single channel harvester of a kind of biological electricity according to claim 1 and quadrature square wave modulation multiple signals, it is special Sign is that the adder operation circuit includes:First resistor and second resistance,
The first signal source is accessed in one end of the first resistor, one end access secondary signal source of the second resistance, and described the The negative polarity input of the other end of one resistance and another termination operational amplifier of the second resistance;Operational amplifier is just One end of polarity input the 4th resistance of termination, the other end ground connection of the 4th resistance;The negative polarity of the operational amplifier is defeated Enter end also while access one end of 3rd resistor, the output end of another termination operational amplifier of the 3rd resistor, output letter Number voltage.
4. the single channel harvester of a kind of biological electricity according to claim 1 and quadrature square wave modulation multiple signals, it is special Sign is that the adder operation circuit includes:First resistor and second resistance,
The first signal source is accessed in one end of the first resistor, one end access secondary signal source of the second resistance, and described the The positive polarity input of the other end of one resistance and another termination operational amplifier of the second resistance;The operational amplifier Negative polarity input connect one end of 3rd resistor and the 4th resistance simultaneously;The other end ground connection of 4th resistance;Described The output end of another termination operational amplifier of three resistance, output signal voltage.
A kind of 5. list of biological electricity being used in claim 1-4 described in any claim and quadrature square wave modulation multiple signals The acquisition method of road harvester, it is characterised in that the described method comprises the following steps:
Mixed signal is converted into data signal by single channel analog-digital converter and is sent into microprocessor;
Microprocessor carries out low-pass filtering treatment to data signal and recovers low frequency bioelectrical signals;Microprocessor is to data signal Carry out separating treatment and obtain PPG signals and bioelectrical signals, and the bias light interference in PPG signals is eliminated;
The valley and peak value of PPG signals are calculated respectively;Again as the suction corresponding to each wavelength of valley and peak computational of PPG signals Luminosity difference DELTA A, the spectral value being made up of absorbance difference Δ A can be obtained;
The microprocessor carries out separating treatment to data signal and obtains PPG signals and bioelectrical signals, and the back of the body in PPG signals Scape light interference the step of being eliminated is specially:
The quadrature square wave signal frequency of microprocessor output driving light emitting diode is respectively 2 times of f, 2 times of f, 1 times of f, 1 times of f, its The phase of middle same frequency square wave differs 90 °, and the sample frequency of single channel analog-digital converter is fs, and fs=8f, and ensure in most high frequency The high and low level intermediate samples of drive signal;
Quadrature square wave signal low and high level sampled point number is n, and is the complete cycle of lowest frequency signal;Ask for respectively n high The voltage magnitude sum of level sampling point, the voltage magnitude sum of n low level sampled point, obtain two voltage magnitude sums Difference;The difference is n times of PPG signals;The interference of bias light and low frequency bioelectrical signals is eliminated, obtains multichannel PPG signals.
CN201510197734.8A 2015-04-23 2015-04-23 The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals Expired - Fee Related CN104783778B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510197734.8A CN104783778B (en) 2015-04-23 2015-04-23 The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510197734.8A CN104783778B (en) 2015-04-23 2015-04-23 The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals

Publications (2)

Publication Number Publication Date
CN104783778A CN104783778A (en) 2015-07-22
CN104783778B true CN104783778B (en) 2018-04-06

Family

ID=53549306

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510197734.8A Expired - Fee Related CN104783778B (en) 2015-04-23 2015-04-23 The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals

Country Status (1)

Country Link
CN (1) CN104783778B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106506004A (en) * 2016-10-20 2017-03-15 天津大学 Bio electricity and the single channel harvester for raising level Quadrature square-wave frequency modulation multiple signals
CN106549670A (en) * 2016-10-20 2017-03-29 天津大学 Multichannel raises the single channel synchronous acquisition device of the bipolar square wave modulated signal of level

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101904118A (en) * 2007-12-20 2010-12-01 皇家飞利浦电子股份有限公司 Electrode diversity for body-coupled communication systems
CN102258366A (en) * 2011-08-17 2011-11-30 天津大学 Orthogonal-square-wave-modulation photoelectric volume pulse wave measuring device and measuring method thereof
CN103142250A (en) * 2013-02-05 2013-06-12 天津大学 Ultrasonic Doppler signal detection circuit
CN103598885A (en) * 2013-11-19 2014-02-26 上海交通大学 Combined surface myoelectricity and near infrared spectrum acquiring device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186110B2 (en) * 2012-09-11 2015-11-17 Covidien Lp Methods and systems for qualifying calculated values based on a statistical metric

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101904118A (en) * 2007-12-20 2010-12-01 皇家飞利浦电子股份有限公司 Electrode diversity for body-coupled communication systems
CN102258366A (en) * 2011-08-17 2011-11-30 天津大学 Orthogonal-square-wave-modulation photoelectric volume pulse wave measuring device and measuring method thereof
CN103142250A (en) * 2013-02-05 2013-06-12 天津大学 Ultrasonic Doppler signal detection circuit
CN103598885A (en) * 2013-11-19 2014-02-26 上海交通大学 Combined surface myoelectricity and near infrared spectrum acquiring device

Also Published As

Publication number Publication date
CN104783778A (en) 2015-07-22

Similar Documents

Publication Publication Date Title
CN102389313B (en) Device and method for measuring square wave modulated photoelectric volume pulse wave
CN102258366B (en) Orthogonal-square-wave-modulation photoelectric volume pulse wave measuring device and measuring method thereof
CN102258365A (en) Sine-wave modulation photo plethysmo graphy measuring device and method
CA1326267C (en) Pulse oximetry system
CN102319075A (en) Blood oxygen saturation measuring device and measuring method
CN100515335C (en) Blood oxygen measuring method and device capable of eliminating moving inteference
CN102429646B (en) Device and method for measuring orthogonal sine wave photoelectric volume pulse wave
CN104825152B (en) The single channel harvester and method of biological electricity and square-wave frequency modulation multiple signals
CN104783778B (en) The single channel harvester and method of biological electricity and quadrature square wave modulation multiple signals
CN104783776B (en) The single channel harvester and method of biological electricity and orthogonal sinusoidal wave modulation multiple signals
CN104883131B (en) The single channel harvester and method of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals
CN104783777B (en) The single channel harvester and method of biological electricity and sine wave modulation multiple signals
CN106419861A (en) Device and method for measuring photo plethysmo graphy by modulation of orthogonal square waves with lifted electrical level
CN104799840B (en) The single channel harvester and method of biological electricity and triangular modulation multiple signals
CN106506004A (en) Bio electricity and the single channel harvester for raising level Quadrature square-wave frequency modulation multiple signals
CN105286793A (en) Physiological signal conditioning circuit and physiological signal acquisition system
CN104510461A (en) Digital full-isolation electrocardiosignal acquisition and noise reduction device and method thereof
CN104783768B (en) A kind of triangular modulation photoplethysmographic measuring method
CN106344000A (en) Single-path collecting device of bioelectricity and raising level triangular wave modulation multipath signal
CN106473732A (en) Biological electricity with raise level Quadrature triangular modulation multiple signals single channel harvester
CN111094941B (en) PPG circuit, biological feature detection device and biological feature detection method
CN106344040A (en) Measuring device and measuring method for raised level square wave modulation photoelectric volume pulse wave
CN106859667B (en) Wireless blood oxygen measuring device
KR20200087422A (en) a auto offset compensation device based binary searching of pulse oximeter
CN220043383U (en) Pre-amplifier applied to sensor and heart rate sensor

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20180406

Termination date: 20210423

CF01 Termination of patent right due to non-payment of annual fee