CN104883131B - The single channel harvester and method of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals - Google Patents
The single channel harvester and method of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals Download PDFInfo
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- CN104883131B CN104883131B CN201510198720.8A CN201510198720A CN104883131B CN 104883131 B CN104883131 B CN 104883131B CN 201510198720 A CN201510198720 A CN 201510198720A CN 104883131 B CN104883131 B CN 104883131B
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Abstract
The invention discloses a kind of bioelectricity and the single channel harvester and method of ORTHOGONAL TRIANGULAR wave modulation multiple signals, the harvester acquires N roads biomedicine signals via analog-digital converter all the way, including being loaded with the high frequency ORTHOGONAL TRIANGULAR wave of PPG signals and low frequency bioelectrical signals.Current signal is converted into default amplitude voltage signal through current/voltage-converted amplifier, default amplitude bioelectrical signals are obtained by bioelectrical signals detection circuit, default amplitude voltage signal obtains mixed signal with default amplitude bioelectrical signals after adder operation circuit is added, mixed signal is converted into digital signal by single channel analog-digital converter, microprocessor handles digital signal, modulation orthogonal triangular signal and low frequency bioelectrical signals are isolated, and multichannel PPG signals are demodulated from modulation orthogonal triangular signal.The characteristics of present invention is realized synchronizes multichannel biomedicine signals acquisition, and simple with circuit via single channel analog-digital converter, and of low cost and measurement is accurate.
Description
Technical field
The present invention relates to Biomedical Signals Acquisition fields more particularly to a kind of bioelectricity to modulate multichannel with ORTHOGONAL TRIANGULAR wave
The single channel harvester and method of signal.
Background technology
The variable quantity of the carrying informations such as voltage signal, represents in an analogue form in its relaxed state, still, in order to
Convenient for computer disposal, transmission and storage will be usually transformed into digital signal by analog-digital converter, therefore be cured in biology
It learns in signal processing, analog-to-digital conversion is essential.
Inventor has found in the implementation of the present invention, in existing multichannel Biomedical Signals Acquisition, need to usually adopt
With the scheme of multi-disc ADC or multiway analog switch collocation monolithic ADC, the former has, and circuit is complicated, system power dissipation height and circuit ruler
The shortcomings that very little big；And the latter then can be in gatherer process, due to the switching of variable connector, insertion switch noise and due to more
Way switch can cause to interfere with each other between adjacent channel signals there are settling time.
Invention content
The single channel harvester and method of multiple signals are modulated with ORTHOGONAL TRIANGULAR wave the present invention provides a kind of bioelectricity, this
Invention realizes analog-to-digital conversion by single channel analog-digital converter to multichannel biomedicine signals, described below：
The single channel harvester of a kind of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals, the single channel harvester packet
It includes：Microprocessor, the microprocessor export different frequency and into the ORTHOGONAL TRIANGULAR waves of 2 times of ratios, and ORTHOGONAL TRIANGULAR wave drives
At least two kinds of light emitting diodes are moved, the light that light emitting diode is sent out is received after tested finger by light-sensitive device, the light-sensitive device
Current signal is converted into, current signal is converted into default amplitude voltage signal through current/voltage-converted amplifier；
The single channel harvester further includes：Low frequency bioelectrical signals detection circuit, adder operation circuit and single channel mould
Number converter；
The low frequency bioelectrical signals detection circuit obtains default amplitude bioelectrical signals, the default amplitude voltage signal
Mixed signal is obtained after the adder operation circuit is added with the default amplitude bioelectrical signals, the mixed signal is by institute
It states single channel analog-digital converter and is converted into digital signal；
The microprocessor handles digital signal, isolates modulation orthogonal triangular signal and low frequency biology telecommunications
Number, and multichannel PPG signals are demodulated from modulation orthogonal triangular signal.
Wherein, the low frequency bioelectrical signals are specially：Any one in ECG, EEG, EMG, EGG and EOG.
Wherein, the adder operation circuit includes：First resistor and second resistance, one end access the of the first resistor
One signal source, one end access second signal source of the second resistance, the other end of the first resistor and the second resistance
Another termination operational amplifier negative polarity input terminal；One end of positive polarity input the 4th resistance of termination of operational amplifier,
The other end ground connection of 4th resistance；The negative polarity input terminal of the operational amplifier also accesses the one of 3rd resistor simultaneously
End, the output terminal of another termination operational amplifier of the 3rd resistor, output signal voltage.
Another embodiment, the adder operation circuit include：First resistor and second resistance, one end of the first resistor
Access the first signal source, one end access second signal source of the second resistance, the other end of the first resistor and described the
The positive polarity input terminal of another termination operational amplifier of two resistance；The negative polarity input terminal of the operational amplifier connects simultaneously
One end of three resistance and the 4th resistance；The other end ground connection of 4th resistance；Another termination operation of the 3rd resistor is put
The output terminal of big device, output signal voltage.
A kind of acquisition method for bioelectricity and the single channel harvester of ORTHOGONAL TRIANGULAR wave modulation multiple signals, the side
Method includes the following steps：
Mixed signal is converted into digital signal by single channel analog-digital converter and is sent into microprocessor；
Microprocessor carries out low-pass filtering treatment to digital signal and recovers low frequency bioelectrical signals；Microprocessor is to number
Signal carries out separating treatment and obtains PPG signals and bioelectrical signals, and the bias light interference in PPG signals is eliminated；
The valley and peak value of PPG signals are calculated respectively；Again as corresponding to each wavelength of valley and peak computational of PPG signals
Absorbance difference Δ A, the spectral value being made of absorbance difference Δ A can be obtained.
Wherein, the microprocessor carries out separating treatment to digital signal and obtains PPG signals and bioelectrical signals, and PPG
Bias light interference the step of being eliminated in signal is specially：
In a cycle for the ORTHOGONAL TRIANGULAR wave that frequency is 1f, respectively to each period of different frequency ORTHOGONAL TRIANGULAR wave
Sampled signal in interior positive and negative half period adds up, and positive half period accumulation result is carried out with negative half-cycle accumulation result
Difference operation is sought, to isolate the ORTHOGONAL TRIANGULAR wave signal of each road different frequency.
The advantageous effect of technical solution provided by the invention is：The present invention cures multichannel biology by single channel analog-digital converter
It learns signal and realizes analog-to-digital conversion, and there is the advantages of circuit is simple, and of low cost and measurement is accurate；And when add operation electricity
During the circuit designed by the invention of road, it may be convenient to get stablize, mixed frequency signal with high accuracy, being easily integrated, and
Circuit cost is reduced, expands the dynamic range of signal, meets a variety of needs in practical application.
Description of the drawings
Fig. 1 is a kind of structure diagram for the single channel harvester that bioelectricity modulates multiple signals with ORTHOGONAL TRIANGULAR wave；
Fig. 2 is the structure diagram of adder operation circuit；
Fig. 3 is another structure diagram of adder operation circuit；
Fig. 4 is the schematic diagram of separation different wave length PPG signals provided by the invention；
Fig. 5 is a kind of flow chart for the single channel acquisition method that bioelectricity modulates multiple signals with ORTHOGONAL TRIANGULAR wave.
In attached drawing, parts list represented by the reference numerals are as follows：
1：Microprocessor； 2：Light emitting diode；
3：Light-sensitive device； 4：Current/voltage-converted amplifier；
5：Low frequency bioelectrical signals detection circuit； 6：Adder operation circuit；
7：Single channel analog-digital converter.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention is made below further
It is described in detail on ground.
Embodiment 1
The single channel harvester of a kind of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals, referring to Fig. 1, single channel acquisition dress
Put including：Microprocessor 1, at least two kinds of light emitting diodes 2, light-sensitive device 3, current/voltage-converted amplifier 4, low frequency bioelectricity
Signal deteching circuit 5, adder operation circuit 6 and single channel analog-digital converter 7,
Microprocessor 1 exports the ORTHOGONAL TRIANGULAR wave of different frequency, and ORTHOGONAL TRIANGULAR wave drives at least two kinds of light emitting diodes 2, hair
The light that optical diode 2 is sent out is received after tested finger by light-sensitive device 3, and light-sensitive device 3 is converted into current signal, current signal
Default amplitude voltage signal is converted into through current/voltage-converted amplifier 4.
Low frequency bioelectrical signals detection circuit 5 obtains default amplitude bioelectrical signals, presets amplitude voltage signal with presetting
Amplitude bioelectrical signals obtain mixed signal after the addition of adder operation circuit 6, and mixed signal is converted by single channel analog-digital converter 7
Into digital signal, microprocessor 1 handles digital signal, isolates modulation orthogonal triangular signal and low frequency biology telecommunications
Number, and multichannel PPG signals are demodulated from modulation orthogonal triangular signal.
Wherein, the quantity of light emitting diode 2 is more than or equal to 2.During specific implementation, the quantity of light emitting diode 2 is according to reality
In set；The amplitude of default amplitude voltage signal and default amplitude bioelectrical signals is according in practical application
Carry out set, during specific implementation, the embodiment of the present invention is without limitation.
Wherein, low frequency bioelectrical signals include：Any one in the bioelectrical signals such as ECG, EEG, EMG, EGG, EOG.
Any one in MCU, ARM, DSP or FPGA may be used in microprocessor 1.Adder operation circuit 6 is using routine on the market
Addition device.
Wherein, the gain of bioelectrical signals detection circuit 5 and bandwidth are by the amplitude and frequency of the bioelectrical signals detected
Range determines.
Embodiment 2
The single channel harvester of a kind of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals, referring to Fig. 1, single channel acquisition dress
Put including：Microprocessor 1, at least two kinds of light emitting diodes 2, light-sensitive device 3, current/voltage-converted amplifier 4, low frequency bioelectricity
Signal deteching circuit 5, adder operation circuit 6 and single channel analog-digital converter 7.The embodiment as different from Example 1, should add
Method computing circuit 6 is realized using the adder operation circuit 6 that the embodiment of the present invention designs, referring to Fig. 2, the adder operation circuit 6
Including：First resistor R1With second resistance R2,
First resistor R1One end access the first signal source V1, second resistance R2One end access second signal source V2, first
Resistance R1The other end and second resistance R2Another termination operational amplifier A negative polarity input terminal；Operational amplifier A is just
The 4th resistance R of polarity input termination4One end, the 4th resistance R4The other end ground connection；The negative polarity input terminal of operational amplifier A
Also access 3rd resistor R simultaneously3One end, 3rd resistor R3Another termination operational amplifier A output terminal, output signal electricity
Press Vo。
First signal source V1, second signal source V2Respectively default amplitude voltage signal and default amplitude bioelectrical signals；
Or, the first signal source V1, second signal source V2Respectively default amplitude bioelectrical signals and default amplitude voltage signal；Signal electricity
Press VoFor mixed signal.
Embodiment 3
The single channel harvester of a kind of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals, referring to Fig. 1, single channel acquisition dress
Put including：Microprocessor 1, at least two kinds of light emitting diodes 2, light-sensitive device 3, current/voltage-converted amplifier 4, low frequency bioelectricity
Signal deteching circuit 5, adder operation circuit 6 and single channel analog-digital converter 7.The embodiment as different from Example 1, should add
The adder operation circuit 6 of design of the embodiment of the present invention may be used to realize in method computing circuit 6, referring to Fig. 3, add operation electricity
Road 6 includes：First resistor R1With second resistance R2,
First resistor R1One end access the first signal source V1, second resistance R2One end access second signal source V2, first
Resistance R1The other end and second resistance R2Another termination operational amplifier A positive polarity input terminal；Operational amplifier A is born
Polarity input terminal meets 3rd resistor R simultaneously3With the 4th resistance R4One end；4th resistance R4The other end ground connection；3rd resistor
R3Another termination operational amplifier A output terminal, output signal voltage Vo。
First signal source V1, second signal source V2Respectively default amplitude voltage signal and default amplitude bioelectrical signals；
Or, the first signal source V1, second signal source V2Respectively default amplitude bioelectrical signals and default amplitude voltage signal；Signal electricity
Press VoFor mixed signal.
Embodiment 4
The single channel acquisition method of a kind of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals, referring to Fig. 4 and Fig. 5, this method
Include the following steps：
101：Mixed signal is converted into digital signal by single channel analog-digital converter 7 and is sent into microprocessor 1；
102：Microprocessor 1 carries out low-pass filtering treatment to digital signal and recovers low frequency bioelectrical signals；Microprocessor 1
Separating treatment is carried out to digital signal and obtains PPG signals and bioelectrical signals, and the interference such as bias light in PPG signals is disappeared
It removes.
Wherein, which is specially：In a cycle for the ORTHOGONAL TRIANGULAR wave that frequency is 1f, respectively to different frequency just
The sampled signal in the positive and negative half period in each period of triangular wave is handed over to add up, positive half period accumulation result is with bearing
Half period accumulation result carries out seeking difference operation, to isolate the ORTHOGONAL TRIANGULAR wave signal of each road different frequency.
It is illustrated by taking the light emitting diode 2 of 4 kinds of wavelength as an example for the sake of concise explanation, it is assumed that λ 1,4 wavelength of λ 2, λ 3 and λ
The driving ORTHOGONAL TRIANGULAR wave frequency rate of light emitting diode be all that 2f but phase differ 90 °, the light emitting diode 2 of 4 wavelength of λ 3 and λ drives
Dynamic ORTHOGONAL TRIANGULAR wave frequency rate differs 90 ° for 1f but phase.
It is assumed that the sample frequency of single channel analog-digital converter 7 is fS, it is assumed that with the highest frequency f of drive signalmax(above-mentioned
In the case of fmax=2f) 4 speeds photosignal is sampled, i.e. fs=8f.
It is assumed that sample frequency fSFar above modulation orthogonal triangular signal and the change frequency of low frequency signal, in minimum driving
The a cycle of signal frequency can be approximately considered each road ORTHOGONAL TRIANGULAR wave signal amplitude and low frequency signal amplitude it is constant.With
For most preceding 16 sampled datas：
Wherein, WithRespectively wavelength X1、λ2、λ3And λ4Optical signal and background signal
Amplitude.
In other words, using every 16 digital signals of sequence as one group of carry out operation：
Obtain the optical signal of 8 times of wavelength X 1And completely eliminate low frequency signalInfluence.
Obtain the optical signal of 8 times of wavelength X 2And completely eliminate low frequency signalInfluence.
Obtain the optical signal of 8 times of wavelength X 3And completely eliminate low frequency signalInfluence.
Obtain 8 times of wavelength X4Optical signalAnd completely eliminate low frequency signalInfluence.
Wherein, WithThe respectively optical signal and background signal of wavelength X 1, λ 2, λ 3 and λ 4
Amplitude.
103：The valley and peak value of PPG signals are calculated respectively；Again by each wavelength institute of the valley and peak computational of PPG signals
Corresponding absorbance difference Δ A, can obtain by Δ Aλ1、ΔAλ2……ΔAλnThe spectral value of composition.
Due to the pulsation phenomenon of artery, it is in cyclically-varying to make blood flow in blood vessel, and blood is height opaque liquid,
Therefore the variation of pulse beating necessarily causes the variation of absorbance.
Consider arteries fullness degree minimum state, the incident light from light source not by pulsatile arterial blood absorption, this
When output intensity ImaxIt is most strong, it can be considered the incident light I of pulsatile arterial blood；And arteries fullness degree highest state corresponds to
At the time of the effect of the valley point of photoelectric sphyg wave, i.e. pulsatile arterial blood is maximum, output intensity I at this timeminIt is most weak, it is dynamic to pulse
The minimum output intensity I of arteries and veins blood.So it is filled by recording artery to the maximum absorbance with during arterial contraction to minimum
Value, it is possible to which eliminating skin histology, subcutaneous tissue etc., all have the characteristics that shadow of the human body component for absorbance of constant absorption
It rings.
If incident intensity is I0, detection light intensity is respectively I when light intensity and arterial contraction are detected when artery is fullminAnd Imax,
Absorbance difference during absorbance and arterial contraction when then artery is full is：
Measure the valley I of each photoplethysmographicminAnd peak ImaxIt can obtain corresponding to photoplethysmographic
Absorbance difference Δ A, can obtain by Δ Aλ1、ΔAλ2……ΔAλnThe spectral value of composition.
That is, the valley and peak value of the PPG signals of wavelength X 1, λ 2, λ 3 and λ 4 are calculated respectively：Iminλ1、Imaxλ1、Iminλ2、
Imaxλ2、Iminλ3、Imaxλ3、Iminλ4And Imaxλ4。
To the model of each device in addition to specified otherwise is done, the model of other devices is not limited the embodiment of the present invention,
As long as the device of above-mentioned function can be completed.
It will be appreciated by those skilled in the art that attached drawing is the schematic diagram of a preferred embodiment, the embodiments of the present invention
Serial number is for illustration only, does not represent the quality of embodiment.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
Claims (5)
1. the single channel harvester of a kind of bioelectricity and ORTHOGONAL TRIANGULAR wave modulation multiple signals, the single channel harvester include：
Microprocessor, the microprocessor export different frequency and into the ORTHOGONAL TRIANGULAR waves of 2 times of ratios, ORTHOGONAL TRIANGULAR wave drive to
Few 2 kinds of light emitting diodes, the light that light emitting diode is sent out are received after tested finger by light-sensitive device, the light-sensitive device conversion
Into current signal, current signal is converted into default amplitude voltage signal through current/voltage-converted amplifier；It is characterized in that,
The single channel harvester further includes：Low frequency bioelectrical signals detection circuit, adder operation circuit and single channel modulus turn
Parallel operation；
The low frequency bioelectrical signals detection circuit obtains default amplitude bioelectrical signals, the default amplitude voltage signal and institute
It states default amplitude bioelectrical signals and obtains mixed signal after adder operation circuit addition, the mixed signal is by the list
Road analog-digital converter is converted into digital signal；
The microprocessor handles digital signal, isolates modulation orthogonal triangular signal and low frequency bioelectrical signals,
And multichannel PPG signals are demodulated from modulation orthogonal triangular signal；
Wherein, the microprocessor handles digital signal, isolates modulation orthogonal triangular signal and low frequency bioelectricity
The step of signal is specially：
In a cycle for the ORTHOGONAL TRIANGULAR wave that frequency is 1f, respectively in each period of different frequency ORTHOGONAL TRIANGULAR wave
Sampled signal in positive and negative half period adds up, and positive half period accumulation result carries out asking poor with negative half-cycle accumulation result
Operation, to isolate the ORTHOGONAL TRIANGULAR wave signal of each road different frequency；
λ 1,2 wavelength of λ the driving ORTHOGONAL TRIANGULAR wave frequency rate of light emitting diode be all that 2f but phase differ 90 °, 4 wavelength of λ 3 and λ
Light emitting diode driving ORTHOGONAL TRIANGULAR wave frequency rate differs 90 ° for 1f but phase；
The sample frequency of single channel analog-digital converter is fS, with the highest frequency f of drive signalmax4 speeds to photosignal into
Row sampling, i.e. fs=8f.
2. the single channel harvester of a kind of bioelectricity according to claim 1 and ORTHOGONAL TRIANGULAR wave modulation multiple signals,
It is characterized in that, the low frequency bioelectrical signals are specially：Any one in ECG, EEG, EMG, EGG and EOG.
3. the single channel harvester of a kind of bioelectricity according to claim 1 and ORTHOGONAL TRIANGULAR wave modulation multiple signals,
It is characterized in that, the adder operation circuit includes：First resistor and second resistance,
The first signal source is accessed in one end of the first resistor, one end access second signal source of the second resistance, and described the
The negative polarity input terminal of the other end of one resistance and another termination operational amplifier of the second resistance；Operational amplifier is just
One end of polarity input the 4th resistance of termination, the other end ground connection of the 4th resistance；The negative polarity of the operational amplifier is defeated
Enter end also while access one end of 3rd resistor, the output terminal of another termination operational amplifier of the 3rd resistor, output letter
Number voltage.
4. the single channel harvester of a kind of bioelectricity according to claim 1 and ORTHOGONAL TRIANGULAR wave modulation multiple signals,
It is characterized in that, the adder operation circuit includes：First resistor and second resistance,
The first signal source is accessed in one end of the first resistor, one end access second signal source of the second resistance, and described the
The positive polarity input terminal of the other end of one resistance and another termination operational amplifier of the second resistance；The operational amplifier
Negative polarity input terminal connect one end of 3rd resistor and the 4th resistance simultaneously；The other end ground connection of 4th resistance；Described
The output terminal of another termination operational amplifier of three resistance, output signal voltage.
5. a kind of bioelectricity for described in any claim in claim 1-4 and ORTHOGONAL TRIANGULAR wave modulation multiple signals
The acquisition method of single channel harvester, which is characterized in that the described method comprises the following steps：
Mixed signal is converted into digital signal by single channel analog-digital converter and is sent into microprocessor；
Microprocessor carries out low-pass filtering treatment to digital signal and recovers low frequency bioelectrical signals；Microprocessor is to digital signal
It carries out separating treatment and obtains PPG signals and bioelectrical signals, and the bias light interference in PPG signals is eliminated；
The valley and peak value of PPG signals are calculated respectively；Again as the suction corresponding to each wavelength of valley and peak computational of PPG signals
Luminosity difference DELTA A can obtain the spectral value being made of absorbance difference Δ A；
Wherein, the microprocessor carries out separating treatment to digital signal and obtains PPG signals and bioelectrical signals, and PPG signals
In bias light interference the step of being eliminated be specially：
In a cycle for the ORTHOGONAL TRIANGULAR wave that frequency is 1f, respectively in each period of different frequency ORTHOGONAL TRIANGULAR wave
Sampled signal in positive and negative half period adds up, and positive half period accumulation result carries out asking poor with negative half-cycle accumulation result
Operation, to isolate the ORTHOGONAL TRIANGULAR wave signal of each road different frequency；
λ 1,2 wavelength of λ the driving ORTHOGONAL TRIANGULAR wave frequency rate of light emitting diode be all that 2f but phase differ 90 °, 4 wavelength of λ 3 and λ
Light emitting diode driving ORTHOGONAL TRIANGULAR wave frequency rate differs 90 ° for 1f but phase；
The sample frequency of single channel analog-digital converter is fS, with the highest frequency f of drive signalmax4 speeds to photosignal into
Row sampling, i.e. fs=8f.
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| CN106473732A (en) * | 2016-10-20 | 2017-03-08 | 天津大学 | Biological electricity with raise level Quadrature triangular modulation multiple signals single channel harvester |
| CN107817376B (en) * | 2017-11-15 | 2023-09-05 | 武汉合智数字能源技术有限公司 | Negative half-cycle waveform blanking amplitude sampling device |
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| CN102258366A (en) * | 2011-08-17 | 2011-11-30 | 天津大学 | Orthogonal-square-wave-modulation photoelectric volume pulse wave measuring device and measuring method thereof |
| CN102389313A (en) * | 2011-08-17 | 2012-03-28 | 天津大学 | Device and method for measuring square wave modulated photoelectric volume pulse wave |
| CN102429646A (en) * | 2011-08-17 | 2012-05-02 | 天津大学 | Device and method for measuring orthogonal sine wave photoelectric volume pulse wave |
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