CN104771818B - Per nasal pressure generator self-adapting calibration system and method - Google Patents
Per nasal pressure generator self-adapting calibration system and method Download PDFInfo
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
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Abstract
The invention discloses a kind of per nasal pressure generator self-adapting calibration system and method, flow detector detects to the flow flowing into Nasal positive airway pressure respirator, pressure-detecting device is used for the airway pressure of pressure generator is detected, control device obtains first detection data corresponding with flow and pressure and the second detection data, record corresponding minimum first detection data when the second detection data is equal to minimum pressure threshold equal to corresponding maximum first detection data during maximum pressure threshold value and the second detection data, N number of first detection data is extracted at regular intervals to the first detection data interval；It is corresponding N number of first detection data that control device controls the flow flowing into respirator respectively, obtain corresponding N number of second detection data, set up the mapping table of N number of second detection data and N number of first detection data, obtain the corresponding relation of flow and pressure, quickly realize the output of pressure precise control, reduce Clinical practice risk.
Description
Technical field
The present invention relates to Medical Instruments, particularly to a kind of per nasal pressure generator self-adapting calibration system and method.
Background technology
Neonate Nasal positive airway pressure respirator is generally divided into two types, and a kind of is mechanical pressure regulating valve
Realize airway pressure type, its operation principle is to connect nasal obstruction using double breathing pipelines, and one end is air inlet, and the other end connects machinery
Pressure-regulating valve, adjusts pressure valve manually and realizes airway pressure regulation.Another is using pressure generator type, and its work is former
Reason is to connect pressure generator using single breathing pipeline, and pressure generator connects patient, by adjusting the flow velocity of pressure generator
Size is realizing the regulation of airway pressure.
The neonate Nasal positive airway pressure respirator of traditional use pressure generator type can manually be adjusted
The mode of amount of restriction size or machine flow automatic regulation size is controlled to airway pressure, but the nasal continuous gas of neonate
The pressure generator that road positive airway pressure breathing uses has many kinds, and the flow-pressure diagram of these pressure generators all differs,
Medical personnel are difficult to judgement and need to adjust great flow to produce great pressure, and the output pressure of pressure generator can not
Precisely controlled, Clinical practice is caused with very big impact.
Additionally, due to respirator inner air path is designed with shunting, that is, it is provided with oxygen sensor, for detecting oxygen concentration, such as scheme
Shown in 10, wherein F1 is expressed as the fresh gas flow that respirator setting is observed, and F2 represents the bypass flow of oxygen sensor, and flows
The flow F3 entering pressure generator deducts F2 for F1, and the flow of user setup is not the flow of actual feed pressure generator,
Therefore it is difficult to control airway pressure exactly by adjusting flow, Clinical practice risk is big.
Content of the invention
Based on this it is necessary to be directed to traditional Nasal positive airway pressure respirator big asking of Clinical practice risk
Topic, proposes a kind of per nasal pressure generator self adaptation that can reduce Nasal positive airway pressure respirator Clinical practice risk
Calibration system and method.
A kind of per nasal pressure generator self-adapting calibration system, including flow detector, pressure-detecting device and control
Device, described control device connects described flow detector and described pressure-detecting device respectively；
Described flow detector is used for the flow flowing into Nasal positive airway pressure respirator is detected, obtains
Take detection signal and send to described control device；Described pressure-detecting device is used for the airway pressure of pressure generator is carried out
Detection, obtains detection signal and sends to described control device；Described control device is used for receiving described flow detector to be sent out
The detection signal sending obtains first detection signal, and the detection signal receiving described pressure-detecting device transmission obtains the second detection letter
Number；Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection number
According to the second detection data, and record corresponding maximum described first when described second detection data is equal to maximum pressure threshold value and examine
Survey data and described second detection data equal to described first detection data of minimum corresponding during minimum pressure threshold, and according to
Described maximum first detection data and described minimum first detection data, carry at regular intervals to described first detection data interval
Take N number of described first detection data；Described control device controls the flow flowing into Nasal positive airway pressure respirator to be
Corresponding described N number of first detection data, described control device obtains corresponding N number of described with described N number of first detection data
Second detection data, sets up the mapping table of described N number of second detection data and described N number of first detection data and exports.
A kind of per nasal pressure generator adaptive calibration method, comprises the following steps：Comprise the following steps：
The gas flow of the input to Nasal positive airway pressure respirator for the flow detector detects, obtains
Detection signal simultaneously sends to control device；
Pressure-detecting device detects to the output pressure of pressure generator, obtains detection signal and sends to described control
Device processed；
The detection signal that control device receives described flow detector transmission obtains first detection signal, receives described pressure
The detection signal that force checking device sends obtains the second detection signal；
Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains first
Detection data and the second detection data；
Corresponding maximum described first when second detection data described in described control device record is equal to maximum pressure threshold value
Detection data and described second detection data are equal to described first detection data of minimum corresponding during minimum pressure threshold；
According to described maximum first detection data and described minimum first detection data, interval to described first detection data
Extract N number of described first detection data at regular intervals；
It is corresponding described N number of that described control device controls the flow flowing into Nasal positive airway pressure respirator
One detection data, described control device obtains N number of described second detection data corresponding with described N number of first detection data, builds
Found the mapping table of described N number of second detection data and described N number of first detection data and export.
Above-mentioned per nasal pressure generator self-adapting calibration system and method, by the flow of pressure generator and output gas
The adaptive calibration of relation between road pressure, has obtained the flow of pressure generator and the corresponding relation of pressure, has solved per nasal
The impact that the difference of continuous positive airway respirator gas circuit diversion design and pressure generator is brought, and calibration process is unmanned
For intervening, calibration data is reliable, stable, and it is defeated to be that full-automatic quick control pressure realized by Nasal positive airway pressure respirator
Go out to provide supplemental characteristic；And no matter using which type of pressure generator, as long as being sent out to pressure using front employing said system
Raw device is calibrated, and just can obtain control of flow and pressure corresponding relation, just can quickly realize pressure essence according to corresponding relation
Really control output, thus reducing Clinical practice risk.
Brief description
Fig. 1 is the structure chart of per nasal pressure generator self-adapting calibration system in an embodiment；
Fig. 2 is to connect between flow detector and pressure-detecting device in oxygen detection device, pressure generator and Fig. 1
Connect schematic diagram；
Fig. 3 is the schematic diagram of pressure-detecting device in an embodiment；
Fig. 4 is the structure chart of per nasal pressure generator self-adapting calibration system in another embodiment；
Fig. 5 is the structure chart of an embodiment lieutenant colonel zero valve；
Fig. 6 is the schematic diagram of an embodiment lieutenant colonel zero control circuit；
Fig. 7 is the flow chart of per nasal pressure generator adaptive calibration method in an embodiment；
Fig. 8 is to obtain maximum first detection data and in an embodiment in per nasal pressure generator adaptive calibration method
The flow chart of little first detection data；
Fig. 9 is to obtain maximum first detection data and in an embodiment in per nasal pressure generator adaptive calibration method
The flow chart of little first detection data；
Figure 10 is the structure chart of traditional Nasal positive airway pressure respirator.
Specific embodiment
Understandable for enabling the above objects, features and advantages of the present invention to become apparent from, below in conjunction with the accompanying drawings to the present invention
Specific embodiment be described in detail.Elaborate a lot of details in order to fully understand this in the following description
Bright.But the present invention can be much to implement different from alternate manner described here, and those skilled in the art can be not
Similar improvement is done, therefore the present invention is not limited by following public specific embodiment in the case of running counter to intension of the present invention.
A kind of per nasal pressure generator self-adapting calibration system, for making the pressure of Nasal positive airway pressure respirator
Forcer can accurately control output airway pressure.Nasal positive airway pressure respirator is by fresh air through air tube
Road is transmitted to pressure generator, and pressure generator pressurizes to air, inputs and supplies patient respiration to patient.As shown in figure 1, warp
One embodiment of nose pressure generator self-adapting calibration system includes flow detector 110, pressure-detecting device 120 and controls
Device 130, control device 130 connection traffic detection means 110 and pressure-detecting device 120 respectively.
Flow detector 110 is used for the flow flowing into Nasal positive airway pressure respirator is detected, obtains
Take detection signal and send to control device 130；As shown in Fig. 2 pressure-detecting device 120 is connected with pressure generator 140, pressure
Force checking device 120 is used for the airway pressure of pressure generator 140 is detected, obtains detection signal and sends to control dress
Put 130；The detection signal that control device 130 is used for receiving flow detector 110 transmission obtains first detection signal, receives pressure
The detection signal that force checking device 120 sends obtains the second detection signal；Control device 130 is to first detection signal and the second inspection
Survey signal carries out analog digital conversion and obtains the first detection data and the second detection data, and records the second detection data equal to maximum pressure
During force threshold, corresponding maximum first detection data and the second detection data are equal to corresponding minimum the during minimum pressure threshold
One detection data, and according to maximum first detection data and minimum first detection data, to the first detection data interval by certain
N number of first detection data is extracted at interval；Control device 130 control flow into Nasal positive airway pressure respirator flow be
Corresponding N number of first detection data, control device 130 obtains N number of second detection data corresponding with N number of first detection data,
Set up the mapping table of N number of second detection data and N number of first detection data and export.
Specifically, pressure-detecting device 120 can adopt high accuracy differential pressure type pressure transducer, and measurement range is 1PSI, defeated
Going out signal is differential signal.Adjust the size of the gas flow flowing into Nasal positive airway pressure respirator, pressure occurs
The airway pressure of device 140 also changes therewith.The gas flow flowing into Nasal positive airway pressure respirator is adjusted,
Obtain the airway pressure of pressure generator 140, that is, obtain the second detection data, and record the second detection data for maximum pressure threshold
Corresponding maximum gas flow and minimum gas flow, i.e. maximum first detection data and minimum when value and minimum pressure threshold
First detection data, wherein maximum pressure threshold value and minimum pressure threshold pre-set.Control device 130 detects to first
N number of first detection data is extracted according to certain interval in the interval of data, according to this N number of first detection data to Input gas stream
Amount is adjusted, and obtains N number of corresponding second detection data, sets up the right of N number of second detection data and N number of first detection data
Answer relation table and export, can achieve the calibration of the corresponding output airway pressure dependence of flow of various pressure generators 140, you can real
Now determine the relation between the flow of pressure generator 140 and output airway pressure.When setting the airway pressure needing, can be fast
Speed finds corresponding flow, realizes the high accuracy control output of airway pressure.
Above-mentioned per nasal pressure generator self-adapting calibration system, by the flow of pressure generator 140 and output airway
The adaptive calibration of relation between pressure, solves Nasal positive airway pressure respirator gas circuit diversion design and pressure is sent out
The impact that the difference of raw device 140 is brought, and calibration process no human intervention, calibration data is reliable, stable, is nasal continuous air flue
Positive airway pressure respirator is realized full-automatic quick control pressure output and is provided supplemental characteristic；And no matter using which type of pressure
Generator 140, as long as calibrating to pressure generator 140 using said system using front, just can obtain flow and pressure control
Corresponding relation processed, just can quickly realize the output of pressure precise control according to corresponding relation, thus reducing Clinical practice risk.
Medical personnel use Nasal positive airway pressure respirator, set the airway pressure force value needing not above-mentioned right
When answering in relation table, control device 130, according to the flow of existing corresponding relation and airway pressure force value, carries out linear fit, obtains
The characteristic curve of relation between flow and airway pressure, the more corresponding flow of airway pressure force value finding setting can be described.
According to different pressure generators 140, maximum pressure threshold value and minimum pressure threshold can be adjusted.In this tool
In body embodiment, maximum pressure threshold value is preferably 15, and minimum pressure threshold is preferably 0.5.According to certain intervals in the first detection
When data interval carries out extracting data, can be to carry out value according to equal interval, also can be taken according to the interval do not waited
Value.
As shown in Fig. 2 above-mentioned per nasal pressure generator self-adapting calibration system also includes volume control device 150, flow
Control device 150 is connected with flow detector 110 and control device 130 respectively, and control device 130 is to volume control device
150 are controlled, and volume control device 150 is used for flow is controlled.I.e. when needs are to the nasal continuous Positive Airway Pressure of inflow
The gas flow of ventilator is adjusted, and realizes the control to gas flow by volume control device 150.
Above-mentioned per nasal pressure generator self-adapting calibration system also includes oxygen detection device 160, for inflow per nasal
In the gas of continuous positive airway respirator, oxygen concentration is detected, specifically, oxygen detection device 160 adopts oxygen to pass
Sensor detects to oxygen concentration.Wherein, volume control device 150 is connected with flow detector 110 flow input, stream
Amount detecting device 110 detection is the total flow flowing into Nasal positive airway pressure respirator, that is, detect is part stream
Enter the gas flow of oxygen detection device 160 and the summation of the gas flow of part feed pressure generator 140.Flow detection fills
Put 110 flow outfan to be connected with oxygen detection device 160, and the flow outfan of flow detector 110 passes through diameter
It is connected with breathing pipeline 170 for 15 millimeters of joints, and is connected with pressure generator 140 by breathing pipeline 170, flow through flow
The gas flow of detection means passes through breathing pipeline 170 part feed pressure generator 140, and gas flow produces shunting, in pressure
Force samples port is connected, by pressure-detecting device 120 and force samples port at the airway pressure sampling tube of forcer 140
Connect, the gas of force samples port output is detected, the airway pressure of monitoring pressure in real time generator 140.Pressure is sent out
Raw device 140 exports to patient to flowing into after its internal gas pressurizes.
Wherein in an embodiment, as shown in figure 3, pressure-detecting device 120 includes testing circuit 122, testing circuit
122 include the first operational amplifier U1A, first resistor R189 and pressure detector U2, and the homophase of the first operational amplifier U1A is defeated
Enter end+connection constant pressure source incoming end VDRI, inverting input-connection pressure detector U2, specifically connect pressure detector U2's
Port-IN, and be grounded by first resistor R189, the outfan of the first operational amplifier U1A connects pressure detector U2, specifically
Connect the port+IN of pressure detector U2.Pressure detector U2 connects control device 130, specifically can pass through port-OUT and end
Mouth+OUT is connected with control device 130.In the present embodiment, the first operational amplifier U1A adopts LMC6482AIM chip, and pressure is examined
Survey device U2 and adopt NPC-1210 chip.
In the present embodiment, pressure-detecting device 120 adopts constant-current source type of drive, using the first operational amplifier U1A and the
One resistance R189 realizes Constant Current-Source Design, may be configured as 1mA to the driving current of pressure detector U2.Pressure detector U2 is used for
The airway pressure of pressure generator 140 is detected, obtains detection signal and send to control device 130.Additionally, detection electricity
Road 122 may also include electric capacity C162, and electric capacity C162 one end connects the outfan of the first operational amplifier U1A, and the other end passes through the
One resistance R189 ground connection.
Wherein in an embodiment, with continued reference to Fig. 3, pressure-detecting device 120 may also include signal amplification circuit
124, signal amplification circuit 124 connects pressure detector U2 and control device 130, for the detection that pressure detector U2 is sent
Signal transmits to control device 130 after being amplified.
Specifically, signal amplification circuit 124 includes instrumentation amplifier U3, second resistance R143,3rd resistor R140
With the 4th resistance R193, the in-phase input end IN+ of instrumentation amplifier U3 is by second resistance R143 and pressure detector U2
Connect, the concrete port+OUT connecting pressure detector U2.The inverting input IN- of instrumentation amplifier U3 passes through the 3rd electricity
Resistance R140 is connected with pressure detector U2, the concrete port-OUT connecting pressure detector U2.Instrumentation amplifier U3's is defeated
Go out to hold OUT to pass through the 4th resistance R193 and connect control device 130, the feedback end REF of instrumentation amplifier U3 accesses constant electricity
Pressure.
Signal amplification circuit 124 may also include resistance R144, electric capacity C163, electric capacity C166, electric capacity C164 and electric capacity C205.
Resistance R144 one end connects the port RG+ of instrumentation amplifier U3, and the other end connects the port of instrumentation amplifier U3
RG-.Electric capacity C163 one end connects the common port of 3rd resistor R140 and instrumentation amplifier U3, and the other end is grounded.Electric capacity
C166 one end connects the common port of 3rd resistor R140 and instrumentation amplifier U3, and the other end connects second resistance R143 and instrument
The common port of table operational amplifier U3.Electric capacity C164 one end connects the public of second resistance R143 and instrumentation amplifier U3
End, the other end is grounded.Electric capacity C205 one end connects the 4th resistance R193 one end away from instrumentation amplifier U3, electric capacity C205
The other end is grounded.
In the present embodiment instrumentation amplifier U3 adopt AD623 chip, have high input impedance, high cmrr,
The feature that low noise, low drifting, temperature stability are good, amplification band width, noise coefficient are little, operational amplifier amplifies 35 times.Logical
Cross and transmit to control device 130 after signal amplification circuit 124 is amplified to detection signal, data acquisition accuracy can be improved.
Further, pressure-detecting device 120 may also include signal filtering circuit 126, and signal filtering circuit 126 connects letter
Number amplifying circuit 124 and control device 130, the signal for exporting to signal amplification circuit 124 transmits after being filtered processing
To control device 130.
Specifically, signal filtering circuit 126 may include the second operational amplifier U1B, the 5th resistance R190, the 6th resistance
R191 and the 7th resistance R192, the 5th resistance R190 and the 6th resistance R191 connect, and the other end of the 5th resistance R190 connects letter
Number amplifying circuit 124, concrete connects the 4th resistance R193.The other end of the 6th resistance R191 connects the second operational amplifier U1B
In-phase input end, the inverting input of the second operational amplifier U1B connects the outfan of the second operational amplifier U1B, second
The outfan of operational amplifier U1B is connected with control device 130 by the 7th resistance R192, specifically can be through port ADC_
Pressure is connected with control device 130.
Signal filtering circuit 126 may also include electric capacity C176, electric capacity C178 and electric capacity C187.Electric capacity C176 one end connects the
Six resistance R191 and the common port of the second operational amplifier U1B, the other end is grounded.Electric capacity C178 one end connects the 5th resistance R190
With the common port of the 6th resistance R191, the outfan of other end connection the second operational amplifier U1B.Electric capacity C187 one end connects the
Seven resistance R192 are grounded away from one end of the second operational amplifier U1B, the electric capacity C187 other end.
Second operational amplifier U1B can adopt TLC2272ACDR chip, utilizes second-order active power filter circuit in the present embodiment
The signal of signal amplification circuit 124 output is filtered after process transmitting to control device 130, can further improve data inspection
The accuracy surveyed.
Wherein in an embodiment, after control device 130 is calculated the second detection data, it is additionally operable to detect to second
Data is filtered processing, and obtains pressure data；Control device 130 record pressure data is equal to corresponding during maximum pressure threshold value
Corresponding minimum first detection data when maximum first detection data and pressure data are equal to minimum pressure threshold, and according to
Big first detection data and minimum first detection data, extract N number of first detection at regular intervals to the first detection data interval
Data；Nasal positive airway pressure respirator is inputted respectively with the corresponding flow of N number of first detection data, control device
130 obtain N number of pressure data corresponding with N number of first detection data, set up N number of pressure data and N number of first detection data
Mapping table simultaneously exports.
In the present embodiment, control device 130 is filtered the number pressure obtaining to the first detection data and the second detection data
According to making that the pressure data obtaining after filtering is more stable, high precision by being filtered processing to the second detection data, control device
130 obtain the corresponding relation between the flow of pressure generator 140 and airway pressure according to the pressure data obtaining after filtering
Calibration is more accurate.
Wherein in an embodiment, as shown in figure 4, per nasal pressure generator self-adapting calibration system also includes school zero dress
Put 180, Zero calibration apparatus 180 connect pressure-detecting device 120 and control device 130, and connect with pressure generator 140.Control
Device 130 timing controlled Zero calibration apparatus 180 are calibrated to pressure-detecting device 120, receive what pressure-detecting device 120 sent
Calibration signal is simultaneously calculated calibration data.
After control device 130 is calculated pressure data, it is additionally operable to carry out school to pressure data respectively according to calibration data
Quasi- process, obtains pressure correction data；Control device 130 record pressure correction data be equal to maximum pressure threshold value when corresponding
Corresponding minimum first detection data when big first detection data and pressure correction data are equal to minimum pressure threshold, and according to
Maximum first detection data and minimum first detection data, extract N number of first inspection at regular intervals to the first detection data interval
Survey data；It is corresponding N number of first detection that control device 130 controls the flow flowing into Nasal positive airway pressure respirator
Data, control device 130 obtains N number of pressure correction data corresponding with N number of first detection data, sets up N number of pressure correction number
According to the mapping table of N number of first detection data and export.
In the present embodiment, also timing carries out calibration process and is calculated calibration data to pressure-detecting device 120.According to
Calibration data carries out calibration process and obtains corresponding pressure correction data to pressure data, is then obtained according to pressure correction data
The mapping table of N number of pressure correction data and N number of first detection data simultaneously exports.Pressure data is calibrated, revises pressure
The impact that force checking device 120 temperature drift and null offset bring, can improve data monitoring degree of accuracy.Further, control
N number of mapping table of the pressure correction obtaining data and the first detection data also can be shown by device 130 by display interface,
So that medical personnel observe.
Wherein in an embodiment, as shown in Figure 5 and Figure 6, Zero calibration apparatus 180 include school zero valve 182 and school zero control
Circuit 184.
School zero valve 182 is used for pressure-detecting device 120 is carried out zero signal calibration, and the present embodiment lieutenant colonel zero valve 182 is adopted
With three-way valve, belong to 23 flow-through valves, by three-way valve to sensor school zero, temperature drift, repeatability etc. can be solved and lead to pressure
The problem that monitoring accuracy is low, error is big.
Specifically, school zero valve 182 includes sampling end 3, atmosphere end 1 and outfan 2, the sampling end 3 of school zero valve 182 and breathing
The gas entry ports connection of pipeline 170, the atmosphere end 1 of school zero valve 182 is used for access environment gas, environmental gas refer specifically to through
The gas of nose pressure generator self-adapting calibration system local environment, in the present embodiment, atmosphere end 1 accesses air, and pressure inputs and is
0.The outfan 2 of school zero valve 182 connects pressure-detecting device 120.
Pressure-detecting device 120 normal work, when the airway pressure of pressure generator 140 is detected, sampling end 3 with
Outfan 2 connects, and during to pressure-detecting device 120 school zero, sampling end 3 is closed, and outfan 2 is connected with atmosphere end 1, pressure detecting
Device 120 generates corresponding calibration signal according to the environmental gas accessing and sends to control device 130.Control device 130 basis
After calibration signal is calculated calibration data, equally also calibration data can be filtered processing, improve data accuracy.Control
Device 130 can be to send per half an hour, one hour or two hours once school zero instruction, and school zero instruction can be that high level also may be used
To be low level.
School zero control circuit 184 connects school zero valve 182 and control device 130, and control device 130 is additionally operable to timing and sends school
Zero instructs to school zero control circuit 184；School zero control circuit 184 controls adopting of school zero valve 182 when not receiving school zero instruction
Sample end 3 is connected with outfan 2, controls the atmosphere end 1 of school zero valve 182 to connect with outfan 2 when receiving school zero instruction.
Wherein in an embodiment, school zero control circuit 184 includes switching tube Q17, the 8th resistance R1 and the 9th resistance
R2.The input of switching tube Q17 is connected with school zero valve 182 by the pin 2 of connectivity port SOLVALVE, power access end
POWER connects school zero valve 182 by the pin 1 of connectivity port SOLVALVE.The control end of switching tube Q17 passes through the 9th resistance R2
The outfan of connecting valve pipe Q17, and by the 8th resistance R1 connect control device 130, specifically through port CTRL_VALVE with
Control device 130 connects；The output head grounding of switching tube Q17.Switching tube Q17 can be specifically audion or metal-oxide-semiconductor, this enforcement
Example breaker in middle pipe Q17 is the N-channel MOS pipe of IRLML2502TRPBF model.
Switching tube Q17 turns on when its control end is for high level, turns off when its control end is for low level.School zero valve 182
On off operating mode according to switching tube Q17 changes specific connected state.So that school zero instructs as high level as a example, switching tube Q17 exists
Conducting when its control end receives school zero instruction, the atmosphere end 1 of school zero valve 182 is connected with outfan 2, to fill to pressure detecting
Put 120 and carry out calibration process.Switching tube Q17 turns off when its control end does not receive school zero instruction, the sampling end of school zero valve 182
3 are connected with outfan 2, so that pressure-detecting device 120 detects to the airway pressure in breathing pipeline 170.
Additionally, school zero control circuit 184 may also include diode D1, electric capacity C1, electric capacity C2, resistance R3, resistance R4 and electricity
Resistance R5.The negative electrode of diode D1 is connected with the pin 1 of connectivity port SOLVALVE, the pin of anode and connectivity port SOLVALVE
2 connections.Electric capacity C1 one end is connected with the pin 1 of connectivity port SOLVALVE, the pin 2 of the other end and connectivity port SOLVALVE
Connect.Resistance R3 and resistance R4 connects and common port connects control device 130 by resistance R5, specifically through port TEST_VALVE
It is connected with control device 130.The other end of resistance R3 is connected with the pin 2 of connectivity port SOLVALVE, the other end of resistance R4
Ground connection.Electric capacity C2 one end connects the common port of resistance R5 and control device 130, and the other end is grounded.
By resistance R3 and resistance R4, the state of school zero valve 182 is carried out with detection generation sampled signal to send to control device
130.According to sampled signal, control device 130 also can judge whether school zero valve 182 exception, such as when school zero control circuit 184
When controlling the sampling end 3 of school zero valve 182 to connect with outfan 2, if judging that sampling end 3 is not connected with outfan 2 according to sampled signal
Lead to or do not connect completely, then judge that exception in school zero valve 182.The exportable prompting message of control device 130 is to inform guardian
Member is overhauled in time, it is to avoid hardware fault impacts to Data Detection, improves per nasal pressure generator adaptive calibration system
The reliability of system.
Present invention also offers a kind of per nasal pressure generator adaptive calibration method, based on above-mentioned per nasal pressure generator
Self-adapting calibration system is realized, and the pressure generator for making Nasal positive airway pressure respirator can accurately control defeated
Gas off-take pressure.Fresh air is transmitted to pressure generator by Nasal positive airway pressure respirator through breathing pipeline, presses
Forcer pressurizes to air, inputs and supplies patient respiration to patient.As shown in fig. 7, per nasal pressure generator self adaptation school
Quasi- method comprises the following steps：
S110：The gas flow of the input to Nasal positive airway pressure respirator for the flow detector is examined
Survey, obtain detection signal and send to control device.
S120：Pressure-detecting device detects to the output pressure of pressure generator, obtain detection signal and send to
Control device.
S130：The detection signal that control device receives flow detector transmission obtains first detection signal, receives pressure
The detection signal that detection means sends obtains the second detection signal.
S140：Control device carries out analog digital conversion to first detection signal and the second detection signal and obtains the first detection data
With the second detection data.
S150：Corresponding maximum first detection data when control device record second detection data is equal to maximum pressure threshold value
And second detection data be equal to minimum pressure threshold when corresponding minimum first detection data.
S160：According to maximum first detection data and minimum first detection data, to the first detection data interval by certain
N number of first detection data is extracted at interval.
S170：It is corresponding N number of first that control device controls the flow flowing into Nasal positive airway pressure respirator
Detection data, control device obtains N number of second detection data corresponding with N number of first detection data, sets up N number of second detection number
According to the mapping table of N number of first detection data and export.
The specific embodiment of above step has been carried out in above-mentioned per nasal pressure generator self-adapting calibration system in detail
Explanation, will not be described here.
Above-mentioned per nasal pressure generator adaptive calibration method, by the flow of pressure generator and output airway pressure
Between relation adaptive calibration, solve Nasal positive airway pressure respirator gas circuit diversion design and pressure generator
The impact that brings of difference, and calibration process no human intervention, calibration data is reliable, stable, is that nasal continuous Positive Airway Pressure leads to
Gas respirator is realized full-automatic quick control pressure output and is provided supplemental characteristic；And no matter occurred using which type of pressure
Device, as long as calibrating to pressure generator using said system using front, just can obtain control of flow and pressure corresponding relation,
The output of pressure precise control just can quickly be realized according to corresponding relation, thus reducing Clinical practice risk.
As shown in figure 8, wherein in an embodiment, above-mentioned steps S150 comprise the following steps：
S152：Control device is filtered to the second detection data processing, and obtains pressure data.
S154：Control device record pressure data be equal to maximum pressure threshold value when corresponding maximum first detection data and
Corresponding minimum first detection data when pressure data is equal to minimum pressure threshold.
Above-mentioned steps S170 are specially：
It is corresponding N number of first detection number that control device controls the flow flowing into Nasal positive airway pressure respirator
According to control device obtains N number of pressure data corresponding with N number of first detection data, sets up N number of pressure data and N number of first inspection
Survey the mapping table of data and export.
In the present embodiment by the second detection data is filtered processing make the pressure data obtaining after filtering more stable,
High precision, control device obtains pressure data and the mapping table of the first detection data according to after filtering, can improve corresponding pass
The accuracy of system.
Further, wherein in an embodiment, per nasal pressure generator adaptive calibration method also includes step：
Control device timing controlled Zero calibration apparatus are calibrated to pressure-detecting device, receive what pressure-detecting device sent
Calibration signal is simultaneously calculated calibration data.
As shown in figure 9, above-mentioned steps S154 include step：
Step S1542：Control device carries out calibration process according to calibration data to pressure data, obtains pressure correction number
According to.
Step S1544：Control device record pressure correction data is equal to corresponding maximum first inspection during maximum pressure threshold value
Survey data and pressure correction data equal to corresponding minimum first detection data during minimum pressure threshold.
It is corresponding N number of first detection number that control device controls the flow flowing into Nasal positive airway pressure respirator
According to control device obtains N number of pressure data corresponding with N number of first detection data, sets up N number of pressure data and N number of first inspection
The step surveyed the mapping table of data and export is specially：
It is corresponding N number of first detection number that control device controls the flow flowing into Nasal positive airway pressure respirator
According to control device obtains N number of pressure correction data corresponding with N number of first detection data, sets up N number of pressure correction data and N
The mapping table of individual first detection data simultaneously exports.
It is that also timing carries out calibration process to pressure-detecting device and is calculated calibration data in the present embodiment.Specifically
Calibrating mode has carried out detailed explanation in above-mentioned per nasal pressure generator self-adapting calibration system, and here is no longer superfluous
State.
Calibration process is carried out according to calibration data to pressure data and obtains corresponding pressure correction data, then according to pressure
Correction data obtains the mapping table of pressure correction data and the first detection data.Pressure data is calibrated, revises pressure
The impact that force checking device temperature drift and null offset bring, can improve data monitoring degree of accuracy.
Further, above-mentioned control device controls the flow flowing into Nasal positive airway pressure respirator is corresponding
N number of first detection data, control device obtains N number of pressure correction data corresponding with N number of first detection data, sets up N number of pressure
After the mapping table of power correction data and N number of first detection data the step that exports, may also include control device will
To pressure correction data and the first detection data the step that shown by display interface of N number of mapping table so that medical care
The observation of personnel.
Above example only have expressed the several embodiments of the present invention, and its description is more concrete and detailed, but can not
Therefore it is interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art,
Without departing from the inventive concept of the premise, some deformation can also be made and improve, these broadly fall into the protection model of the present invention
Enclose.Therefore, the protection domain of patent of the present invention should be defined by claims.
Claims (10)
1. a kind of per nasal pressure generator self-adapting calibration system is it is characterised in that include flow detector, pressure detecting dress
Put and control device, described control device connects described flow detector and described pressure-detecting device respectively；
Described flow detector is used for the flow flowing into Nasal positive airway pressure respirator is detected, obtains inspection
Survey signal and send to described control device；Described pressure-detecting device is used for the airway pressure of pressure generator is examined
Survey, obtain detection signal and send to described control device；Described control device is used for receiving described flow detector transmission
Detection signal obtain first detection signal, receive the detection signal that described pressure-detecting device sends and obtain the second detection letter
Number；Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection number
According to the second detection data, and record corresponding maximum described first when described second detection data is equal to maximum pressure threshold value and examine
Survey data and described second detection data equal to described first detection data of minimum corresponding during minimum pressure threshold, and according to
Described maximum first detection data and described minimum first detection data obtain the first detection data interval, detect to described first
Data interval extracts N number of described first detection data at regular intervals；Described control device is just controlling the nasal continuous air flue of inflow
The flow of pressure ventilator is corresponding described N number of first detection data, and described control device obtains and described N number of first inspection
Survey corresponding N number of described second detection data of data, set up described N number of second detection data and described N number of first detection data
Mapping table and export.
2. per nasal pressure generator self-adapting calibration system according to claim 1 is it is characterised in that also include flow control
Device processed and oxygen detection device, described volume control device is connected with described control device, described volume control device and institute
The flow input stating flow detector connects, the flow outfan of described flow detector respectively with described oxygen detection
Device and described pressure generator connect；Described volume control device is used for inflow Nasal positive airway pressure respirator
Gas flow be adjusted, described oxygen detection device be used for flow into Nasal positive airway pressure respirator gas
Middle oxygen concentration is detected.
3. per nasal pressure generator self-adapting calibration system according to claim 1 is it is characterised in that described pressure detecting
Device includes testing circuit, and described testing circuit includes the first operational amplifier, first resistor and pressure detector, and described first
The in-phase input end of operational amplifier connects constant pressure source incoming end, and inverting input connects described pressure detector, and passes through institute
State first resistor ground connection, the outfan of described first operational amplifier connects described pressure detector, and described pressure detector is even
Connect described control device；Described pressure detector is used for the airway pressure of pressure generator is detected, obtains detection signal
And send to described control device.
4. per nasal pressure generator self-adapting calibration system according to claim 3 is it is characterised in that described pressure detecting
Device also includes signal amplification circuit, and described signal amplification circuit connects described pressure detector and control device, for institute
State pressure detector transmission detection signal be amplified after transmit to described control device；Described signal amplification circuit includes instrument
Table operational amplifier, second resistance, 3rd resistor and the 4th resistance, the in-phase input end of described instrumentation amplifier passes through institute
State second resistance to be connected with described pressure detector, the inverting input of described instrumentation amplifier is by described 3rd resistor
It is connected with described pressure detector, the outfan of described instrumentation amplifier passes through described 4th resistance and connects described control dress
Put, the feedback end of described instrumentation amplifier accesses constant voltage.
5. per nasal pressure generator self-adapting calibration system according to claim 4 is it is characterised in that described pressure detecting
Device also includes signal filtering circuit, described signal filtering circuit include the second operational amplifier, the 5th resistance, the 6th resistance and
7th resistance, described 5th resistance and the 6th resistant series, the other end of described 5th resistance connects described signal amplification circuit,
The other end of described 6th resistance connects the in-phase input end of described second operational amplifier, described second operational amplifier anti-
Phase input connects the outfan of described second operational amplifier, and the outfan of described second operational amplifier passes through the described 7th
Resistance is connected with described control device.
6. per nasal pressure generator self-adapting calibration system according to claim 1 is it is characterised in that described control device
After being calculated described second detection data, it is additionally operable to described second detection data is filtered process, obtains pressure data；
When pressure data described in described control device record is equal to maximum pressure threshold value described first detection data of corresponding maximum and
Described pressure data is equal to described first detection data of minimum corresponding during minimum pressure threshold, and examines according to described maximum first
Survey data and described minimum first detection data, N number of described first is extracted at regular intervals to described first detection data interval
Detection data；It is corresponding described N number of that described control device controls the flow flowing into Nasal positive airway pressure respirator
Control device described in first detection data obtains N number of described pressure data corresponding with described N number of first detection data, sets up institute
State the mapping table of N number of pressure data and described N number of first detection data and export.
7. per nasal pressure generator self-adapting calibration system according to claim 6 is it is characterised in that also include school zero dress
Put, described Zero calibration apparatus connect described pressure-detecting device and control device, and connect with described pressure generator；Described control
Described in device timing controlled, Zero calibration apparatus are calibrated to described pressure-detecting device, receive what described pressure-detecting device sent
Calibration signal is simultaneously calculated calibration data；
After described control device is calculated described pressure data, it is additionally operable to according to described calibration data, described pressure data be entered
Row calibration process, obtains pressure correction data；Pressure correction data described in described control device record is equal to maximum pressure threshold value
When corresponding described first detection data of maximum and described pressure correction data be equal to minimum pressure threshold when corresponding minimum
Described first detection data, and according to described maximum first detection data and described minimum first detection data, to described first
N number of described first detection data is extracted in detection data interval at regular intervals；Described control device controls the nasal continuous gas of inflow
The flow of road positive airway pressure respirator is corresponding described N number of first detection data, and described control device obtains and described N number of the
The corresponding N number of described pressure correction data of one detection data, sets up described N number of pressure correction data and described N number of first detection
The mapping table of data simultaneously exports.
8. per nasal pressure generator self-adapting calibration system according to claim 7 is it is characterised in that described Zero calibration apparatus
Including school zero valve and school zero control circuit,
Described school zero valve includes sampling end, atmosphere end and outfan, and the sampling end of described school zero valve is with described pressure generator even
Logical, the atmosphere end of described school zero valve is used for access environment gas, and the outfan of described school zero valve connects described pressure-detecting device；
Described school zero control circuit connects described school zero valve and control device, and described control device is additionally operable to timing and sends school zero finger
Make to described school zero control circuit；Described school zero control circuit controls described school zero valve when not receiving described school zero instruction
Sampling end is connected with outfan, controls the atmosphere end of described school zero valve to connect with outfan when receiving described school zero instruction.
9. a kind of per nasal pressure generator adaptive calibration method is it is characterised in that comprise the following steps：Comprise the following steps：
The gas flow of the input to Nasal positive airway pressure respirator for the flow detector detects, obtains detection
Signal simultaneously sends to control device；
Pressure-detecting device detects to the output pressure of pressure generator, obtains detection signal and sends to described control dress
Put；
The detection signal that control device receives described flow detector transmission obtains first detection signal, receives described pressure inspection
The detection signal surveying device transmission obtains the second detection signal；
Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection
Data and the second detection data；
Second detection data described in described control device record is equal to corresponding maximum described first during maximum pressure threshold value and detects
Data and described second detection data are equal to described first detection data of minimum corresponding during minimum pressure threshold；
First detection data interval is obtained according to described maximum first detection data and described minimum first detection data, to described
N number of described first detection data is extracted in first detection data interval at regular intervals；
It is corresponding described N number of first inspection that described control device controls the flow flowing into Nasal positive airway pressure respirator
Survey data, described control device obtains N number of described second detection data corresponding with described N number of first detection data, sets up institute
State the mapping table of N number of second detection data and described N number of first detection data and export.
10. per nasal pressure generator adaptive calibration method according to claim 9 is it is characterised in that described control fills
Put and record when described second detection data is equal to maximum pressure threshold value described first detection data of corresponding maximum and described the
Two detection datas include step equal to the step of described first detection data of minimum corresponding during minimum pressure threshold：
Control device is filtered to described second detection data processing, and obtains pressure data；
Pressure data described in described control device record is equal to described first detection data of maximum corresponding during maximum pressure threshold value
And described pressure data is equal to described first detection data of corresponding minimum during minimum pressure threshold；
It is corresponding described N number of first inspection that described control device controls the flow flowing into Nasal positive airway pressure respirator
Survey data, described control device obtains N number of described second detection data corresponding with described N number of first detection data, sets up institute
The step stated the mapping table of N number of second detection data and described N number of first detection data and export is specially：
It is corresponding described N number of first inspection that described control device controls the flow flowing into Nasal positive airway pressure respirator
Survey data, described control device obtains N number of described pressure data corresponding with described N number of first detection data, sets up described N number of
The mapping table of pressure data and described N number of first detection data simultaneously exports.
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| CN201510093439.8A CN104771818B (en) | 2015-03-02 | 2015-03-02 | Per nasal pressure generator self-adapting calibration system and method |
| PCT/CN2015/099809 WO2016138791A1 (en) | 2015-03-02 | 2015-12-30 | System and method for adaptive calibration of nasal pressure generator |
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| CN201510093439.8A CN104771818B (en) | 2015-03-02 | 2015-03-02 | Per nasal pressure generator self-adapting calibration system and method |
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| CN104771818B (en) * | 2015-03-02 | 2017-03-01 | 深圳市科曼医疗设备有限公司 | Per nasal pressure generator self-adapting calibration system and method |
| CN106902437A (en) * | 2015-12-22 | 2017-06-30 | 北京谊安医疗系统股份有限公司 | A kind of control system for controlling flow |
| CN106595944A (en) * | 2016-12-16 | 2017-04-26 | 深圳市美好创亿医疗科技有限公司 | Breathing product test method and terminal |
| CN111888599B (en) * | 2018-12-10 | 2022-10-04 | 深圳市科曼医疗设备有限公司 | Pressure maintaining device of breathing machine |
| CN112169103A (en) * | 2020-09-27 | 2021-01-05 | 湖南明康中锦医疗科技发展有限公司 | Method for adaptively adjusting voltage increasing and decreasing speed, application of method and respiration support equipment |
| CN113546260B (en) * | 2021-06-07 | 2023-08-22 | 中国人民解放军总医院第一医学中心 | Method, apparatus and storage medium for monitoring for use anomalies in transnasal high flow |
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| CH568756A5 (en) * | 1973-09-07 | 1975-11-14 | Hoffmann La Roche | |
| EP0788805A3 (en) * | 1996-02-06 | 1998-05-13 | DeVilbiss Health Care, Inc. | Control for CPAP apparatus |
| EP1355689B1 (en) * | 2000-12-29 | 2010-05-26 | Resmed Ltd. | Characterisation of mask systems |
| US7938114B2 (en) * | 2001-10-12 | 2011-05-10 | Ric Investments Llc | Auto-titration bi-level pressure support system and method of using same |
| EP1699514B1 (en) * | 2003-12-29 | 2019-09-25 | ResMed Pty Ltd | Mechanical ventilation in the presence of sleep disordered breathing |
| US7886739B2 (en) * | 2005-10-11 | 2011-02-15 | Carefusion 207, Inc. | System and method for circuit compliance compensated volume control in a patient respiratory ventilator |
| EP1951347B1 (en) * | 2005-11-16 | 2017-01-11 | TreyMed, Inc. | Side-stream respiratory gas monitoring system |
| US7509957B2 (en) * | 2006-02-21 | 2009-03-31 | Viasys Manufacturing, Inc. | Hardware configuration for pressure driver |
| CN101541366B (en) * | 2006-08-30 | 2013-07-17 | 雷斯梅德有限公司 | Determination of leak during CPAP treatment |
| GB2472592A (en) * | 2009-08-11 | 2011-02-16 | 3M Innovative Properties Co | A control unit for respirator |
| AU2011251644B2 (en) * | 2010-05-11 | 2015-03-05 | Koninklijke Philips Electronics N.V. | Inductance compensation in a pressure support system |
| CN102397609A (en) * | 2010-09-07 | 2012-04-04 | 北京航天长峰股份有限公司 | Ventilation method for ensuring volume and limiting pressure of anesthesia machine and breathing machine |
| CN103071213A (en) * | 2011-10-25 | 2013-05-01 | 北京航天长峰股份有限公司 | Leakage compensation method for single-loop non-invasive ventilators |
| EP2906277A2 (en) * | 2012-10-10 | 2015-08-19 | Koninklijke Philips N.V. | Adaptive patient circuit compensation with pressure sensor at mask apparatus |
| CN103893882B (en) * | 2012-12-28 | 2016-03-02 | 北京谊安医疗系统股份有限公司 | A kind of anesthesia machine flow modification method and device |
| CN104771818B (en) * | 2015-03-02 | 2017-03-01 | 深圳市科曼医疗设备有限公司 | Per nasal pressure generator self-adapting calibration system and method |
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Effective date of registration: 20190228 Address after: 518000 South Ring Road, Matian Street, Guangming District, Shenzhen City, Guangdong Province Co-patentee after: Seventh Medical Center, General Hospital of the Chinese People's Liberation Army Patentee after: Shenzhen Comen Medical Instruments Co., Ltd. Address before: 518052 Nanshan Avenue Nanyou Fourth Industrial Zone, Nanshan District, Shenzhen City, Guangdong Province Patentee before: Shenzhen Comen Medical Instruments Co., Ltd. |