CN104771818A - Self-adaptation calibration system and method for passing-nose pressure generator - Google Patents
Self-adaptation calibration system and method for passing-nose pressure generator Download PDFInfo
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Abstract
The invention discloses a self-adaptation calibration system and method for a passing-nose pressure generator. A flow measurement device conducts detection on flow flowing into a passing-nose nasal continuous positive airway positive pressure ventilation breathing machine; a pressure detection device is used for detecting the airway pressure of the pressure generator; a control device obtains first detection data and second detection data corresponding to the flow and the pressure and records the maximum first detection data, equal to the maximum pressure threshold value, in the second detection data and the minimum first detection data, equal to the minimum pressure threshold value, in the second detection data, and N first detection data are extracted according to a certain interval within the section of the first detection data; and the control device controls the flow flowing into the breathing machine to be N corresponding first detection data, obtains the N second detection data corresponding to the N first detection data and builds the congruent relationship table between the N second detection data and the N first detection data; the congruent relationship between the flow and the pressure is obtained, pressure output accurate control is rapidly achieved, and the clinic using risks are reduced.
Description
Technical field
The present invention relates to Medical Instruments, particularly a kind of per nasal pressure generator self-adapting calibration system and method.
Background technology
Neonate Nasal positive airway pressure respirator is generally divided into two types, a kind of realize airway pressure type for mechanical pressure control valve, its operation principle connects nasal obstruction for adopting two breathing pipeline, one end is air inlet, the other end connects mechanical pressure-regulating valve, and manual adjustments pressure valve realizes airway pressure and regulates.Another is for using pressure generator type, and its operation principle is for adopting single breathing pipeline Bonding pressure generator, and pressure generator connects patient, by the adjustment regulating the flow velocity size of pressure generator to realize airway pressure.
The neonate Nasal positive airway pressure respirator of traditional use pressure generator type controls airway pressure by the mode of manual adjustments uninterrupted or machine flow automatic regulation size, but the pressure generator that neonate Nasal positive airway pressure breathes use has a variety of, the flow-pressure diagram of these pressure generators is all not identical, medical personnel are difficult to judgement to be needed to regulate great flow could produce great pressure, the output pressure of pressure generator can not be precisely controlled, causes very large impact to Clinical practice.
In addition, because respirator inner air path is designed with shunting, namely oxygen sensor is provided with, for detecting oxygen concentration, as shown in Figure 10, wherein F1 is expressed as the fresh gas flow that respirator arranges observation, F2 represents the bypass flow of oxygen sensor, and the flow F3 of feed pressure generator to be F1 deduct F2, the flow that user is arranged not is the flow of actual inflow pressure generator, therefore be difficult to control airway pressure exactly by adjust flux, Clinical practice has a big risk.
Summary of the invention
Based on this, be necessary the problem had a big risk for traditional Nasal positive airway pressure respirator Clinical practice, propose a kind of per nasal pressure generator self-adapting calibration system and the method that can reduce Nasal positive airway pressure respirator Clinical practice risk.
A kind of per nasal pressure generator self-adapting calibration system, comprise flow detector, pressure-detecting device and control device, described control device connects described flow detector and described pressure-detecting device respectively;
The flow that described flow detector is used for flowing into Nasal positive airway pressure respirator detects, and obtains detection signal and is sent to described control device; Described pressure-detecting device is used for detecting the airway pressure of pressure generator, obtains detection signal and is sent to described control device; Described control device obtains the first detection signal for the detection signal receiving the transmission of described flow detector, and the detection signal receiving the transmission of described pressure-detecting device obtains the second detection signal; Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection data and the second detection data, and record described second and to detect when data equal maximum pressure threshold value corresponding maximum described first and detect data and described second and to detect when data equal minimum pressure threshold corresponding minimum described first and detect data, and detect data and described minimum first detection data according to described maximum first, detect data interval to described first and extract N number of described first detection data at regular intervals; The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtain detecting with described N number of first data corresponding N number of described second detect data, set up described N number of second and detect data and described N number of first and detect the mapping table of data and export.
A kind of per nasal pressure generator adaptive calibration method, comprises the following steps: comprise the following steps:
The gas flow of flow detector to the input of Nasal positive airway pressure respirator detects, and obtains detection signal and is sent to control device;
The output pressure of pressure-detecting device to pressure generator detects, and obtains detection signal and is sent to described control device;
The detection signal that control device receives the transmission of described flow detector obtains the first detection signal, and the detection signal receiving the transmission of described pressure-detecting device obtains the second detection signal;
Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection data and the second detection data;
Described in described control device record, second to detect when data equal maximum pressure threshold value corresponding maximum described first and detects data and described second and to detect when data equal minimum pressure threshold corresponding minimum described first and detect data;
Detect data and described minimum first according to described maximum first and detect data, detect data interval to described first and extract N number of described first detection data at regular intervals;
The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtain detecting with described N number of first data corresponding N number of described second detect data, set up described N number of second and detect data and described N number of first and detect the mapping table of data and export.
Above-mentioned per nasal pressure generator self-adapting calibration system and method, by the adaptive calibration to relation between the flow of pressure generator and output airway pressure, obtain the flow of pressure generator and the corresponding relation of pressure, the impact that the difference solving Nasal positive airway pressure respirator gas circuit diversion design and pressure generator is brought, and calibration process is without human intervention, calibration data is reliable, stable, provides supplemental characteristic for Nasal positive airway pressure respirator realizes full-automatic quick control Output pressure; And no matter use which type of pressure generator, as long as adopt said system to calibrate pressure generator before using, just can obtain control of flow and pressure corresponding relation, just can realize pressure fast according to corresponding relation and accurately control to export, thus reduce Clinical practice risk.
Accompanying drawing explanation
Fig. 1 is the structure chart of per nasal pressure generator self-adapting calibration system in an embodiment;
Fig. 2 is catenation principle figure between flow detector and pressure-detecting device in oxygen detection device, pressure generator and Fig. 1;
Fig. 3 is the schematic diagram of pressure-detecting device in an embodiment;
Fig. 4 is the structure chart of per nasal pressure generator self-adapting calibration system in another embodiment;
Fig. 5 is the structure chart of embodiment lieutenant colonel zero valve;
Fig. 6 is the schematic diagram of embodiment lieutenant colonel zero control circuit;
Fig. 7 is the flow chart of per nasal pressure generator adaptive calibration method in an embodiment;
Fig. 8 obtains maximum first to detect the flow chart that data and minimum first detect data in per nasal pressure generator adaptive calibration method in one embodiment;
Fig. 9 obtains maximum first to detect the flow chart that data and minimum first detect data in per nasal pressure generator adaptive calibration method in one embodiment;
Figure 10 is the structure chart of traditional Nasal positive airway pressure respirator.
Detailed description of the invention
For enabling above-mentioned purpose of the present invention, feature and advantage become apparent more, are described in detail the specific embodiment of the present invention below in conjunction with accompanying drawing.Set forth a lot of detail in the following description so that fully understand the present invention.But the present invention can be much different from alternate manner described here to implement, those skilled in the art can when without prejudice to doing similar improvement when intension of the present invention, therefore the present invention is by the restriction of following public specific embodiment.
A kind of per nasal pressure generator self-adapting calibration system, can accurately control output airway pressure for making the pressure generator of Nasal positive airway pressure respirator.Fresh air is transferred to pressure generator through breathing pipeline by Nasal positive airway pressure respirator, and pressure generator pressurizes to air, inputs to patient for patient respiration.As shown in Figure 1, an embodiment of per nasal pressure generator self-adapting calibration system comprises flow detector 110, pressure-detecting device 120 and control device 130, and control device 130 is connection traffic checkout gear 110 and pressure-detecting device 120 respectively.
Flow detector 110, for detecting the flow flowing into Nasal positive airway pressure respirator, obtains detection signal and is sent to control device 130; As shown in Figure 2, pressure-detecting device 120 is connected with pressure generator 140, and pressure-detecting device 120, for detecting the airway pressure of pressure generator 140, obtains detection signal and is sent to control device 130; Control device 130 obtains the first detection signal for the detection signal receiving flow detector 110 transmission, and the detection signal receiving pressure-detecting device 120 transmission obtains the second detection signal; Control device 130 carries out analog digital conversion to the first detection signal and the second detection signal and obtains the first detection data and the second detection data, and to record when the second detection data equal maximum pressure threshold value corresponding maximum first and detect data and second and to detect when data equal minimum pressure threshold corresponding minimum first and detect data, and detect data and minimum first detection data according to maximum first, detect data interval to first and extract N number of first detection data at regular intervals; The flow that control device 130 controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device 130 obtain detecting with N number of first data corresponding N number of second detect data, set up N number of second and detect data and N number of first and detect the mapping table of data and export.
Particularly, pressure-detecting device 120 can adopt high accuracy differential pressure type pressure transducer, and measuring range is 1PSI, outputs signal as differential signal.Regulate the size of the gas flow flowing into Nasal positive airway pressure respirator, the airway pressure of pressure generator 140 also changes thereupon.The gas flow flowing into Nasal positive airway pressure respirator is regulated, obtain the airway pressure of pressure generator 140, namely obtain second and detect data, and record the second detection data be maximum pressure threshold value and minimum pressure threshold time corresponding maximum gas flow and minimum gas flow, namely maximum first detect data and minimum first detection data, wherein maximum pressure threshold value and minimum pressure threshold pre-set.Control device 130 extracts N number of first to the interval that first detects data according to certain interval and detects data, according to these N number of first detection data, input gas flow is regulated, obtain N number of correspondence second detects data, set up N number of second detection data and N number of first detect the mapping table of data and export, the calibration of the corresponding output airway pressure dependence of flow of various pressure generator 140 can be realized, can realize determining the relation between the flow of pressure generator 140 and output airway pressure.When setting the airway pressure needed, can find corresponding flow fast, the high accuracy realizing airway pressure controls to export.
Above-mentioned per nasal pressure generator self-adapting calibration system, by the adaptive calibration to relation between the flow of pressure generator 140 and output airway pressure, the impact that the difference solving Nasal positive airway pressure respirator gas circuit diversion design and pressure generator 140 is brought, and calibration process is without human intervention, calibration data is reliable, stable, provides supplemental characteristic for Nasal positive airway pressure respirator realizes full-automatic quick control Output pressure; And no matter use which type of pressure generator 140, as long as adopt said system to calibrate pressure generator 140 before using, just can obtain control of flow and pressure corresponding relation, just can realize pressure fast according to corresponding relation and accurately control to export, thus reduce Clinical practice risk.
Medical personnel use Nasal positive airway pressure respirator, when the airway pressure force value that setting needs is not in above-mentioned mapping table, control device 130 is according to the flow of existing corresponding relation and airway pressure force value, carry out linear fit, obtain the characteristic curve that can describe relation between flow and airway pressure, then the flow finding the airway pressure force value of setting corresponding.
According to different pressure generators 140, can adjust maximum pressure threshold value and minimum pressure threshold.In this specific embodiment, maximum pressure threshold value is preferably 15, and minimum pressure threshold is preferably 0.5.According to certain intervals when the first detection data interval carries out extraction data, can be carry out value according to equal interval, also can carry out value according to the interval of not waiting.
As shown in Figure 2, above-mentioned per nasal pressure generator self-adapting calibration system also comprises volume control device 150, volume control device 150 is connected with flow detector 110 and control device 130 respectively, control device 130 pairs of volume control devices 150 control, and volume control device 150 is for controlling flow.Namely when needing the gas flow to flowing into Nasal positive airway pressure respirator to regulate, the control to gas flow is realized by volume control device 150.
Above-mentioned per nasal pressure generator self-adapting calibration system also comprises oxygen detection device 160, detect for oxygen concentration in the gas to inflow Nasal positive airway pressure respirator, particularly, oxygen detection device 160 adopts oxygen sensor to detect oxygen concentration.Wherein, volume control device 150 is connected with flow detector 110 flow input, what flow detector 110 detected is the total flow flowing into Nasal positive airway pressure respirator, and what namely detect is the summation that part flows into the gas flow of oxygen detection device 160 and the gas flow of part feed pressure generator 140.The flow outfan of flow detector 110 is connected with oxygen detection device 160, and the joint that the flow outfan of flow detector 110 is 15 millimeters by diameter is connected with breathing pipeline 170, and be connected with pressure generator 140 by breathing pipeline 170, flow through the gas flow of flow detector by breathing pipeline 170 part feed pressure generator 140, gas flow produces shunting, in the airway pressure sampling tube place Bonding pressure sample port of pressure generator 140, pressure-detecting device 120 is connected with force samples port, the gas that force samples port exports is detected, the airway pressure of monitoring pressure in real time generator 140.Pressure generator 140 exports patient to after pressurizeing to the gas flowing into its inside.
Wherein in an embodiment, as shown in Figure 3, pressure-detecting device 120 comprises testing circuit 122, testing circuit 122 comprises the first operational amplifier U1A, the first resistance R189 and pressure detector U2, in-phase input end+connection constant pressure source incoming end the VDRI of the first operational amplifier U1A, inverting input-Bonding pressure detector U2, port-the IN of concrete Bonding pressure detector U2, and by the first resistance R189 ground connection, the outfan Bonding pressure detector U2 of the first operational amplifier U1A, the port+IN of concrete Bonding pressure detector U2.Pressure detector U2 connection control device 130, is specifically connected with control device 130 with port+OUT by port-OUT.In the present embodiment, the first operational amplifier U1A adopts LMC6482AIM chip, and pressure detector U2 adopts NPC-1210 chip.
In the present embodiment, pressure-detecting device 120 adopts constant-current source type of drive, utilizes the first operational amplifier U1A and the first resistance R189 to realize Constant Current-Source Design, can be set to 1mA to the drive current of pressure detector U2.Pressure detector U2 is used for detecting the airway pressure of pressure generator 140, obtains detection signal and is sent to control device 130.In addition, testing circuit 122 also can comprise electric capacity C162, and electric capacity C162 one end connects the outfan of the first operational amplifier U1A, and the other end is by the first resistance R189 ground connection.
Wherein in an embodiment, continue with reference to Fig. 3, pressure-detecting device 120 also can comprise signal amplification circuit 124, signal amplification circuit 124 Bonding pressure detector U2 and control device 130, transfers to control device 130 after the detection signal for sending pressure detector U2 amplifies.
Particularly, signal amplification circuit 124 comprises instrumentation amplifier U3, the second resistance R143, the 3rd resistance R140 and the 4th resistance R193, the in-phase input end IN+ of instrumentation amplifier U3 is connected with pressure detector U2 by the second resistance R143, the port+OUT of concrete Bonding pressure detector U2.The inverting input IN-of instrumentation amplifier U3 is connected with pressure detector U2 by the 3rd resistance R140, the port-OUT of concrete Bonding pressure detector U2.The outfan OUT of instrumentation amplifier U3 accesses constant voltage by the feedback end REF of the 4th resistance R193 connection control device 130, instrumentation amplifier U3.
Signal amplification circuit 124 also can comprise resistance R144, electric capacity C163, electric capacity C166, electric capacity C164 and electric capacity C205.Resistance R144 one end connects the port RG+ of instrumentation amplifier U3, and the other end connects the port RG-of instrumentation amplifier U3.Electric capacity C163 one end connects the common port of the 3rd resistance R140 and instrumentation amplifier U3, other end ground connection.Electric capacity C166 one end connects the common port of the 3rd resistance R140 and instrumentation amplifier U3, and the other end connects the common port of the second resistance R143 and instrumentation amplifier U3.Electric capacity C164 one end connects the common port of the second resistance R143 and instrumentation amplifier U3, other end ground connection.Electric capacity C205 one end connects the 4th resistance R193 one end away from instrumentation amplifier U3, electric capacity C205 other end ground connection.
In the present embodiment, instrumentation amplifier U3 adopts AD623 chip, and have high input impedance, high cmrr, low noise, low drifting, temperature stability is good, amplification band is wide, noise coefficient is little feature, operational amplifier amplifies 35 times.Transfer to control device 130 after being amplified by signal amplification circuit 124 pairs of detection signals, data acquisition accuracy can be improved.
Further, pressure-detecting device 120 also can comprise signal filtering circuit 126, signal filtering circuit 126 connection signal amplifying circuit 124 and control device 130, transfer to control device 130 after the signal for exporting signal amplification circuit 124 carries out Filtering Processing.
Particularly, signal filtering circuit 126 can comprise the second operational amplifier U1B, the 5th resistance R190, the 6th resistance R191 and the 7th resistance R192,5th resistance R190 and the 6th resistance R191 connects, the other end connection signal amplifying circuit 124 of the 5th resistance R190, concrete connection the 4th resistance R193.The other end of the 6th resistance R191 connects the in-phase input end of the second operational amplifier U1B, the inverting input of the second operational amplifier U1B connects the outfan of the second operational amplifier U1B, the outfan of the second operational amplifier U1B is connected with control device 130 by the 7th resistance R192, specifically can be connected with control device 130 through port ADC_Pressure.
Signal filtering circuit 126 also can comprise electric capacity C176, electric capacity C178 and electric capacity C187.Electric capacity C176 one end connects the common port of the 6th resistance R191 and the second operational amplifier U1B, other end ground connection.Electric capacity C178 one end connects the common port of the 5th resistance R190 and the 6th resistance R191, and the other end connects the outfan of the second operational amplifier U1B.Electric capacity C187 one end connects the 7th resistance R192 one end away from the second operational amplifier U1B, electric capacity C187 other end ground connection.
Second operational amplifier U1B can adopt TLC2272ACDR chip, transfers to control device 130, can further improve the accuracy of Data Detection in the present embodiment after utilizing second-order active power filter circuit to carry out Filtering Processing to the signal that signal amplification circuit 124 exports.
Wherein in an embodiment, after control device 130 calculates the second detection data, also carrying out Filtering Processing for detecting data to second, obtaining pressure data; Control device 130 to record when pressure data equals maximum pressure threshold value corresponding maximum first and to detect when data and pressure data equal minimum pressure threshold corresponding minimum first and detect data, and detect data and minimum first detection data according to maximum first, detect data interval to first and extract N number of first detection data at regular intervals; N number of first is inputted respectively to Nasal positive airway pressure respirator and detects flow corresponding to data, control device 130 obtains detecting N number of pressure data corresponding to data with N number of first, sets up N number of pressure data and N number of first and detects the mapping table of data and export.
In the present embodiment, control device 130 detects data and second to first and detects data and carry out the pressure data that filtering obtains, by detecting second, the data pressure data that carries out obtaining after Filtering Processing makes filtering is more stable, precision is high, and the calibration that control device 130 obtains the corresponding relation between the flow of pressure generator 140 and airway pressure according to the pressure data obtained after filtering is more accurate.
Wherein in an embodiment, as shown in Figure 4, per nasal pressure generator self-adapting calibration system also comprises Zero calibration apparatus 180, Zero calibration apparatus 180 Bonding pressure checkout gear 120 and control device 130, and is communicated with pressure generator 140.Control device 130 timing controlled Zero calibration apparatus 180 pairs of pressure-detecting devices 120 are calibrated, and receive the calibrating signal of pressure-detecting device 120 transmission and calculate calibration data.
After control device 130 calculates pressure data, also for carrying out calibration process to pressure data respectively according to calibration data, obtain pressure correction data; Control device 130 to record when pressure correction data equal maximum pressure threshold value corresponding maximum first and to detect when data and pressure correction data equal minimum pressure threshold corresponding minimum first and detect data, and detect data and minimum first detection data according to maximum first, detect data interval to first and extract N number of first detection data at regular intervals; The flow that control device 130 controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device 130 obtains detecting N number of pressure correction data corresponding to data with N number of first, sets up N number of pressure correction data and N number of first and detects the mapping table of data and export.
In the present embodiment, also timing is carried out calibration process to pressure-detecting device 120 and calculates calibration data.According to calibration data, calibration process is carried out to pressure data and obtain corresponding pressure correction data, then obtain N number of pressure correction data and N number of first according to pressure correction data and detect the mapping table of data and export.Pressure data is calibrated, the impact that correction pressure-detecting device 120 temperature drift and null offset bring, data monitoring degree of accuracy can be improved.Further, N number of mapping table that the pressure correction data obtained and first also can be detected data by control device 130 is shown by display interface, so that medical personnel observe.
Wherein in an embodiment, as shown in Figure 5 and Figure 6, Zero calibration apparatus 180 comprises school zero valve 182 and school zero control circuit 184.
School zero valve 182 is for carrying out zero signal calibration to pressure-detecting device 120, the present embodiment lieutenant colonel zero valve 182 adopts three-way valve, belong to 23 flow-through valves, by three-way valve to sensor school zero, temperature drift, repeatability etc. can be solved and cause the problem that pressure monitoring precision is low, error is large.
Particularly, school zero valve 182 comprises sampling end 3, atmosphere end 1 and outfan 2, the sampling end 3 of school zero valve 182 is communicated with the gas entry ports of breathing pipeline 170, the atmosphere end 1 of school zero valve 182 is for accessing environmental gas, environmental gas specifically refers to the gas of environment residing for per nasal pressure generator self-adapting calibration system, in the present embodiment, atmosphere end 1 accesses air, and pressure is input as 0.The outfan 2 Bonding pressure checkout gear 120 of school zero valve 182.
Pressure-detecting device 120 normally works, when the airway pressure of pressure generator 140 is detected, sampling end 3 is communicated with outfan 2, during to pressure-detecting device 120 school zero, sampling end 3 is closed, outfan 2 is communicated with atmosphere end 1, and pressure-detecting device 120 generates corresponding calibrating signal according to the environmental gas of access and is sent to control device 130.After control device 130 calculates calibration data according to calibrating signal, equally also can carry out Filtering Processing to calibration data, improve data accuracy.Control device 130 can be per half an hour, one hour or two hours send once school zero instruction, and school zero instruction can be high level also can be low level.
School zero control circuit 184 connects school zero valve 182 and control device 130, control device 130 also for timed sending school zero instruction to school zero control circuit 184; School zero control circuit 184 controls school zero valve 182 sampling end 3 when not receiving school zero instruction is communicated with outfan 2, and the atmosphere end 1 controlling school zero valve 182 when receiving school zero instruction is communicated with outfan 2.
Wherein in an embodiment, school zero control circuit 184 comprises switching tube Q17, the 8th resistance R1 and the 9th resistance R2.The input of switching tube Q17 is connected with school zero valve 182 by the pin two of connectivity port SOLVALVE, and power access end POWER connects school zero valve 182 by the pin one of connectivity port SOLVALVE.The control end of switching tube Q17 passes through the outfan of the 9th resistance R2 connecting valve pipe Q17, and by the 8th resistance R1 connection control device 130, is specifically connected with control device 130 through port CTRL_VALVE; The output head grounding of switching tube Q17.Switching tube Q17 can be specifically audion or metal-oxide-semiconductor, and the present embodiment breaker in middle pipe Q17 is the N-channel MOS pipe of IRLML2502TRPBF model.
Switching tube Q17 conducting when its control end is high level, turns off when its control end is low level.School zero valve 182 changes concrete connected state according to the on off operating mode of switching tube Q17.For school zero instruction for high level, switching tube Q17 conducting when its control end receives school zero instruction, the atmosphere end 1 of school zero valve 182 is communicated with outfan 2, to carry out calibration process to pressure-detecting device 120.Switching tube Q17 turns off when its control end does not receive school zero instruction, and the sampling end 3 of school zero valve 182 is communicated with outfan 2, so that the airway pressure in pressure-detecting device 120 pairs of breathing pipelines 170 detects.
In addition, school zero control circuit 184 also can comprise diode D1, electric capacity C1, electric capacity C2, resistance R3, resistance R4 and resistance R5.The negative electrode of diode D1 is connected with the pin one of connectivity port SOLVALVE, and anode is connected with the pin two of connectivity port SOLVALVE.Electric capacity C1 one end is connected with the pin one of connectivity port SOLVALVE, and the other end is connected with the pin two of connectivity port SOLVALVE.Resistance R3 and resistance R4 connects and common port passes through resistance R5 connection control device 130, is specifically connected with control device 130 through port TEST_VALVE.The other end of resistance R3 is connected with the pin two of connectivity port SOLVALVE, the other end ground connection of resistance R4.The common port of electric capacity C2 one end contact resistance R5 and control device 130, other end ground connection.
Carry out detection generation sampled signal by the state of resistance R3 and resistance R4 to school zero valve 182 and be sent to control device 130.According to sampled signal, control device 130 also can judge whether school zero valve 182 occurs exception, as when the sampling end 3 that school zero control circuit 184 controls school zero valve 182 is communicated with outfan 2, if judge that sampling end 3 is not communicated with outfan 2 or is not communicated with completely according to sampled signal, then judge that exception appears in school zero valve 182.The exportable prompting message of control device 130, to inform that care provider overhauls in time, avoids hardware fault to impact Data Detection, improves the reliability of per nasal pressure generator self-adapting calibration system.
Present invention also offers a kind of per nasal pressure generator adaptive calibration method, realizing based on above-mentioned per nasal pressure generator self-adapting calibration system, output airway pressure can accurately be controlled for making the pressure generator of Nasal positive airway pressure respirator.Fresh air is transferred to pressure generator through breathing pipeline by Nasal positive airway pressure respirator, and pressure generator pressurizes to air, inputs to patient for patient respiration.As shown in Figure 7, per nasal pressure generator adaptive calibration method comprises the following steps:
S110: the gas flow of flow detector to the input of Nasal positive airway pressure respirator detects, obtains detection signal and is sent to control device.
S120: the output pressure of pressure-detecting device to pressure generator detects, obtains detection signal and is sent to control device.
S130: the detection signal that control device receives flow detector transmission obtains the first detection signal, the detection signal receiving pressure-detecting device transmission obtains the second detection signal.
S140: control device carries out analog digital conversion to the first detection signal and the second detection signal and obtains the first detection data and the second detection data.
S150: control device record second to detect when data equal maximum pressure threshold value corresponding maximum first and detects data and second and to detect when data equal minimum pressure threshold corresponding minimum first and detect data.
S160: detect data and minimum first according to maximum first and detect data, detects data interval to first and extracts N number of first detection data at regular intervals.
S170: the flow that control device controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device obtain detecting with N number of first data corresponding N number of second detect data, set up N number of second and detect data and N number of first and detect the mapping table of data and export.
The detailed description of the invention of above step has been carried out detailed explanation and has been illustrated in above-mentioned per nasal pressure generator self-adapting calibration system, does not repeat them here.
Above-mentioned per nasal pressure generator adaptive calibration method, by the adaptive calibration to relation between the flow of pressure generator and output airway pressure, the impact that the difference solving Nasal positive airway pressure respirator gas circuit diversion design and pressure generator is brought, and calibration process is without human intervention, calibration data is reliable, stable, provides supplemental characteristic for Nasal positive airway pressure respirator realizes full-automatic quick control Output pressure; And no matter use which type of pressure generator, as long as adopt said system to calibrate pressure generator before using, just can obtain control of flow and pressure corresponding relation, just can realize pressure fast according to corresponding relation and accurately control to export, thus reduce Clinical practice risk.
As shown in Figure 8, wherein in an embodiment, above-mentioned steps S150 comprises the following steps:
S152: control device detects data to second and carries out Filtering Processing, obtains pressure data.
S154: when control device record pressure data equals maximum pressure threshold value, corresponding maximum first to detect when data and pressure data equal minimum pressure threshold corresponding minimum first and detect data.
Above-mentioned steps S170 is specially:
The flow that control device controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device obtains detecting N number of pressure data corresponding to data with N number of first, sets up N number of pressure data and N number of first and detects the mapping table of data and export.
Pressure data by carrying out obtaining after Filtering Processing makes filtering to the second detection data in the present embodiment is more stable, precision is high, and control device detects the mapping table of data according to obtaining pressure data and first after filtering, can improve the accuracy of corresponding relation.
Further, wherein in an embodiment, per nasal pressure generator adaptive calibration method also comprises step:
Control device timing controlled Zero calibration apparatus is calibrated pressure-detecting device, receives the calibrating signal of pressure-detecting device transmission and calculates calibration data.
As shown in Figure 9, above-mentioned steps S154 comprises step:
Step S1542: control device carries out calibration process according to calibration data to pressure data, obtains pressure correction data.
Step S1544: when control device record pressure correction data equal maximum pressure threshold value, corresponding maximum first to detect when data and pressure correction data equal minimum pressure threshold corresponding minimum first and detect data.
The flow that control device controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device obtains detecting N number of pressure data corresponding to data with N number of first, sets up N number of pressure data and N number of first and detects the mapping table of data and the step that exports is specially:
The flow that control device controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device obtains detecting N number of pressure correction data corresponding to data with N number of first, sets up N number of pressure correction data and N number of first and detects the mapping table of data and export.
Namely be that also timing is carried out calibration process to pressure-detecting device and calculated calibration data in the present embodiment.Concrete calibrating mode has carried out detailed explanation and has illustrated in above-mentioned per nasal pressure generator self-adapting calibration system, does not repeat them here.
According to calibration data, calibration process is carried out to pressure data and obtain corresponding pressure correction data, then obtain according to pressure correction data the mapping table that pressure correction data and first detect data.Pressure data is calibrated, the impact that correction pressure-detecting device temperature drift and null offset bring, data monitoring degree of accuracy can be improved.
Further, the flow that above-mentioned control device controls to flow into Nasal positive airway pressure respirator is corresponding N number of first detection data, control device obtains detecting N number of pressure correction data corresponding to data with N number of first, set up N number of pressure correction data and N number of first detect data mapping table and after the step that exports, also can comprise the step that N number of mapping table that the pressure correction data obtained and first detect data is shown by display interface by control device, so that the observation of medical personnel.
Above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (10)
1. a per nasal pressure generator self-adapting calibration system, is characterized in that, comprises flow detector, pressure-detecting device and control device, and described control device connects described flow detector and described pressure-detecting device respectively;
The flow that described flow detector is used for flowing into Nasal positive airway pressure respirator detects, and obtains detection signal and is sent to described control device; Described pressure-detecting device is used for detecting the airway pressure of pressure generator, obtains detection signal and is sent to described control device; Described control device obtains the first detection signal for the detection signal receiving the transmission of described flow detector, and the detection signal receiving the transmission of described pressure-detecting device obtains the second detection signal; Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection data and the second detection data, and record described second and to detect when data equal maximum pressure threshold value corresponding maximum described first and detect data and described second and to detect when data equal minimum pressure threshold corresponding minimum described first and detect data, and detect data and described minimum first detection data according to described maximum first, detect data interval to described first and extract N number of described first detection data at regular intervals; The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtain detecting with described N number of first data corresponding N number of described second detect data, set up described N number of second and detect data and described N number of first and detect the mapping table of data and export.
2. per nasal pressure generator self-adapting calibration system according to claim 1, it is characterized in that, also comprise volume control device and oxygen detection device, described volume control device is connected with described control device, described volume control device is connected with the flow input of described flow detector, and the flow outfan of described flow detector is connected with described oxygen detection device and described pressure generator respectively; The gas flow that described volume control device is used for flowing into Nasal positive airway pressure respirator regulates, and described oxygen detection device is used for oxygen concentration in the gas to inflow Nasal positive airway pressure respirator and detects.
3. per nasal pressure generator self-adapting calibration system according to claim 1, it is characterized in that, described pressure-detecting device comprises testing circuit, described testing circuit comprises the first operational amplifier, the first resistance and pressure detector, the in-phase input end of described first operational amplifier connects constant pressure source incoming end, inverting input connects described pressure detector, and by described first resistance eutral grounding, the outfan of described first operational amplifier connects described pressure detector, and described pressure detector connects described control device; Described pressure detector is used for detecting the airway pressure of pressure generator, obtains detection signal and is sent to described control device.
4. per nasal pressure generator self-adapting calibration system according to claim 3, it is characterized in that, described pressure-detecting device also comprises signal amplification circuit, described signal amplification circuit connects described pressure detector and control device, transfers to described control device after the detection signal for sending described pressure detector amplifies; Described signal amplification circuit comprises instrumentation amplifier, the second resistance, the 3rd resistance and the 4th resistance, the in-phase input end of described instrumentation amplifier is connected with described pressure detector by described second resistance, the inverting input of described instrumentation amplifier is connected with described pressure detector by described 3rd resistance, the outfan of described instrumentation amplifier connects described control device by described 4th resistance, the feedback end access constant voltage of described instrumentation amplifier.
5. per nasal pressure generator self-adapting calibration system according to claim 4, it is characterized in that, described pressure-detecting device also comprises signal filtering circuit, described signal filtering circuit comprises the second operational amplifier, 5th resistance, 6th resistance and the 7th resistance, described 5th resistance and the 6th resistant series, the other end of described 5th resistance connects described signal amplification circuit, the other end of described 6th resistance connects the in-phase input end of described second operational amplifier, the inverting input of described second operational amplifier connects the outfan of described second operational amplifier, the outfan of described second operational amplifier is connected with described control device by described 7th resistance.
6. per nasal pressure generator self-adapting calibration system according to claim 1, is characterized in that, after described control device calculates described second detection data, also carrying out Filtering Processing for detecting data to described second, obtaining pressure data; When pressure data described in described control device record equals maximum pressure threshold value, corresponding maximum described first to detect when data and described pressure data equal minimum pressure threshold corresponding minimum described first and detects data, and detect data and described minimum first detection data according to described maximum first, detect data interval to described first and extract N number of described first detection data at regular intervals; The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtains detecting N number of described pressure data corresponding to data with described N number of first, sets up described N number of pressure data and described N number of first and detects the mapping table of data and export.
7. per nasal pressure generator self-adapting calibration system according to claim 6, it is characterized in that, also comprise Zero calibration apparatus, described Zero calibration apparatus connects described pressure-detecting device and control device, and is communicated with described pressure generator; Described in described control device timing controlled, Zero calibration apparatus is calibrated described pressure-detecting device, receives the calibrating signal of described pressure-detecting device transmission and calculates calibration data;
After described control device calculates described pressure data, also for carrying out calibration process according to described calibration data to described pressure data, obtain pressure correction data; When pressure correction data described in described control device record equal maximum pressure threshold value, corresponding maximum described first to detect when data and described pressure correction data equal minimum pressure threshold corresponding minimum described first and detects data, and detect data and described minimum first detection data according to described maximum first, detect data interval to described first and extract N number of described first detection data at regular intervals; The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtains detecting N number of described pressure correction data corresponding to data with described N number of first, sets up described N number of pressure correction data and described N number of first and detects the mapping table of data and export.
8. per nasal pressure generator self-adapting calibration system according to claim 7, is characterized in that, described Zero calibration apparatus comprises school zero valve and school zero control circuit,
Described school zero valve comprises sampling end, atmosphere end and outfan, and the sampling end of described school zero valve is communicated with described pressure generator, and the atmosphere end of described school zero valve is for accessing environmental gas, and the outfan of described school zero valve connects described pressure-detecting device;
Described school zero control circuit connects described school zero valve and control device, and described control device is also for timed sending school zero instruction extremely described school zero control circuit; Described school zero control circuit controls described school zero valve sampling end when not receiving described school zero instruction is communicated with outfan, and the atmosphere end controlling described school zero valve when receiving described school zero instruction is communicated with outfan.
9. a per nasal pressure generator adaptive calibration method, is characterized in that, comprise the following steps: comprise the following steps:
The gas flow of flow detector to the input of Nasal positive airway pressure respirator detects, and obtains detection signal and is sent to control device;
The output pressure of pressure-detecting device to pressure generator detects, and obtains detection signal and is sent to described control device;
The detection signal that control device receives the transmission of described flow detector obtains the first detection signal, and the detection signal receiving the transmission of described pressure-detecting device obtains the second detection signal;
Described control device carries out analog digital conversion to described first detection signal and described second detection signal and obtains the first detection data and the second detection data;
Described in described control device record, second to detect when data equal maximum pressure threshold value corresponding maximum described first and detects data and described second and to detect when data equal minimum pressure threshold corresponding minimum described first and detect data;
Detect data and described minimum first according to described maximum first and detect data, detect data interval to described first and extract N number of described first detection data at regular intervals;
The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtain detecting with described N number of first data corresponding N number of described second detect data, set up described N number of second and detect data and described N number of first and detect the mapping table of data and export.
10. per nasal pressure generator adaptive calibration method according to claim 9, it is characterized in that, described in described control device record, second to detect when data equal maximum pressure threshold value corresponding maximum described first and detects data and described second and detect the minimum described first corresponding step detecting data when data equal minimum pressure threshold and comprise step:
Control device detects data to described second and carries out Filtering Processing, obtains pressure data;
When pressure data described in described control device record equals maximum pressure threshold value, corresponding maximum described first to detect when data and described pressure data equal minimum pressure threshold corresponding minimum described first and detects data;
The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtain detecting with described N number of first data corresponding N number of described second detect data, set up described N number of second and detect the step that mapping table that data and described N number of first detect data also exports and be specially:
The flow that described control device controls to flow into Nasal positive airway pressure respirator is corresponding described N number of first detection data, described control device obtains detecting N number of described pressure data corresponding to data with described N number of first, sets up described N number of pressure data and described N number of first and detects the mapping table of data and export.
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| CN201510093439.8A CN104771818B (en) | 2015-03-02 | 2015-03-02 | Per nasal pressure generator self-adapting calibration system and method |
| PCT/CN2015/099809 WO2016138791A1 (en) | 2015-03-02 | 2015-12-30 | System and method for adaptive calibration of nasal pressure generator |
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| CN201510093439.8A CN104771818B (en) | 2015-03-02 | 2015-03-02 | Per nasal pressure generator self-adapting calibration system and method |
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| CN104771818A true CN104771818A (en) | 2015-07-15 |
| CN104771818B CN104771818B (en) | 2017-03-01 |
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| CN113546260A (en) * | 2021-06-07 | 2021-10-26 | 中国人民解放军总医院第一医学中心 | Method, apparatus and storage medium for monitoring transnasal high flow usage anomalies |
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| CN104771818B (en) | 2017-03-01 |
| WO2016138791A1 (en) | 2016-09-09 |
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Effective date of registration: 20190228 Address after: 518000 South Ring Road, Matian Street, Guangming District, Shenzhen City, Guangdong Province Co-patentee after: Seventh Medical Center, General Hospital of the Chinese People's Liberation Army Patentee after: Shenzhen Comen Medical Instruments Co., Ltd. Address before: 518052 Nanshan Avenue Nanyou Fourth Industrial Zone, Nanshan District, Shenzhen City, Guangdong Province Patentee before: Shenzhen Comen Medical Instruments Co., Ltd. |