CN104771779A - Functional dressing and preparation method thereof - Google Patents
Functional dressing and preparation method thereof Download PDFInfo
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- CN104771779A CN104771779A CN201510214862.9A CN201510214862A CN104771779A CN 104771779 A CN104771779 A CN 104771779A CN 201510214862 A CN201510214862 A CN 201510214862A CN 104771779 A CN104771779 A CN 104771779A
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- high molecular
- molecular polymer
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- polyhydric alcohol
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- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 229920000642 polymer Polymers 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 150000007524 organic acids Chemical class 0.000 claims abstract description 11
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims abstract description 6
- 239000007788 liquid Substances 0.000 claims description 18
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 17
- 239000003292 glue Substances 0.000 claims description 17
- 229920001661 Chitosan Polymers 0.000 claims description 10
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 10
- 125000002091 cationic group Chemical group 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 8
- 125000000129 anionic group Chemical group 0.000 claims description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 238000007602 hot air drying Methods 0.000 claims description 6
- 239000002002 slurry Substances 0.000 claims description 6
- 239000004310 lactic acid Substances 0.000 claims description 5
- 235000014655 lactic acid Nutrition 0.000 claims description 5
- 108010010803 Gelatin Proteins 0.000 claims description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 claims description 4
- 239000008273 gelatin Substances 0.000 claims description 4
- 235000019322 gelatine Nutrition 0.000 claims description 4
- 235000011852 gelatine desserts Nutrition 0.000 claims description 4
- 239000012535 impurity Substances 0.000 claims description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 claims description 4
- 230000000873 masking effect Effects 0.000 claims description 3
- 239000004745 nonwoven fabric Substances 0.000 claims description 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims description 2
- 229920001817 Agar Polymers 0.000 claims description 2
- 229920002749 Bacterial cellulose Polymers 0.000 claims description 2
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 claims description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 2
- 102000008186 Collagen Human genes 0.000 claims description 2
- 108010035532 Collagen Proteins 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 235000011054 acetic acid Nutrition 0.000 claims description 2
- 239000008272 agar Substances 0.000 claims description 2
- 235000010443 alginic acid Nutrition 0.000 claims description 2
- 229920000615 alginic acid Polymers 0.000 claims description 2
- 239000005016 bacterial cellulose Substances 0.000 claims description 2
- 230000004071 biological effect Effects 0.000 claims description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 2
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 2
- 235000015165 citric acid Nutrition 0.000 claims description 2
- 239000011248 coating agent Substances 0.000 claims description 2
- 238000000576 coating method Methods 0.000 claims description 2
- 239000002131 composite material Substances 0.000 claims description 2
- 238000007766 curtain coating Methods 0.000 claims description 2
- 230000000850 deacetylating effect Effects 0.000 claims description 2
- 235000019253 formic acid Nutrition 0.000 claims description 2
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 239000000230 xanthan gum Substances 0.000 claims description 2
- 229920001285 xanthan gum Polymers 0.000 claims description 2
- 235000010493 xanthan gum Nutrition 0.000 claims description 2
- 229940082509 xanthan gum Drugs 0.000 claims description 2
- 206010052428 Wound Diseases 0.000 abstract description 33
- 208000027418 Wounds and injury Diseases 0.000 abstract description 33
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 7
- 230000035876 healing Effects 0.000 abstract description 5
- 230000000474 nursing effect Effects 0.000 abstract description 4
- 208000025865 Ulcer Diseases 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 208000002847 Surgical Wound Diseases 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 239000012567 medical material Substances 0.000 abstract description 2
- 206010053615 Thermal burn Diseases 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 230000036314 physical performance Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
- 238000003756 stirring Methods 0.000 description 11
- 238000000034 method Methods 0.000 description 9
- 239000004744 fabric Substances 0.000 description 5
- 239000010408 film Substances 0.000 description 5
- 239000004677 Nylon Substances 0.000 description 4
- 230000003110 anti-inflammatory effect Effects 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 229920001778 nylon Polymers 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 3
- 229910021641 deionized water Inorganic materials 0.000 description 3
- 239000000341 volatile oil Substances 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 108010025899 gelatin film Proteins 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 229920005615 natural polymer Polymers 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000006196 deacetylation Effects 0.000 description 1
- 238000003381 deacetylation reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 229940040145 liniment Drugs 0.000 description 1
- 239000000865 liniment Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Abstract
The invention relates to the field of medical materials, in particular to a preparation method of a functional dressing product. A functional dressing is made of a positive ion macromolecular polymer, a negative ion macromolecular polymer and an auxiliary material. The positive ion macromolecular polymer accounts for 2% to 6% by weight, the negative ion macromolecular polymer accounts for 2% to 6% by weight, the auxiliary material is made of polyhydric alcohol, biological active matter, organic acid and water, the polyhydric alcohol accounts for 2.8% to 10% by weight, the biological active matter accounts for 0.2% to 2% by weight, the organic acid accounts for 0.5% to 3% by weight, and the water accounts for 4% to 92% by weight. By the adoption of the functional dressing, various physical performance requirements of a wound for the dressing are met, the anti-bacterial effect, the inflammation diminishing effect and the healing promoting effect are further achieved, and the functional dressing can be used for the surgical wound and ulceration face healing, sinus wound instillation, burn and scald wound surface nursing and the like.
Description
Technical field
The present invention relates to a kind of field of medical materials, and the method for making of functional dressings goods.
Background technology
Medical wound dressing medically generally refers to and temporaryly covers on wound, has the covering of protective effect.During skin injury; suitable wound dressing is selected to cover on wound; Bleeding control can be assisted, protect from infection and absorb secretions; thus promotion wound healing; current medical wound dressing is generally coordinate medicine to make with gauze or non-woven fabrics and Cotton Gossypii; wound can be protected from mechanical injuries, prevent wound infected, but the performance such as it is antibacterial, imbibition, antiinflammatory is not fully up to expectations.
Summary of the invention
Technical problem to be solved by this invention be add in masking or wound Liniment a kind of in Yunnan, Guizhou, the ground growing plants such as Hainan Island be named as Herba Blumeae Balsamiferae, its branch and leaf are through steam distillation extraction and isolation gained ethereal oil.It has the effect of antibacterial, antiinflammatory, promotion organization healing, experiment display 1% effectively can suppress growth of microorganism in 48 hours, a class natural polymer thing is coordinated to obtain a class wound care membrane material of functional type, add the membrane material of this natural essential oil composition, except meeting wound to except the multiple physical property needs of dressing, more there are antibacterial, antiinflammatory, short more effect.Can be used for surgical wound, ulcer surface healing, sinus wound area, empyrosis wound surface nursing etc.
For solving the technical problem that the present invention proposes, technical scheme provided by the invention is, by following weight percent meter: a kind of functional dressings is characterized in that, be made up of the high molecular polymer of cationic and the high molecular polymer of anionic property and adjuvant, the high molecular polymer of cationic described by weight percentage, accounting 2% ~ 6%; The high molecular polymer of described anionic property, accounting 2% ~ 6%; Described adjuvant is that polyhydric alcohol, biological active matter, organic acid and moisture are made, and wherein polyhydric alcohol accounting is 2.8% ~ 10%, biological active matter is 0.2% ~ 2%, organic acid is 0.5% ~ 3% and moisture content 4% ~ 92%.
Further, described cationic high molecular polymer is chitosan, and described deacetylating degree of chitosan is 40 ~ 80% or hydroxyethyl chitosan.
Further, described the moon is one or more in carboxymethyl cellulose, xanthan gum, Algin, gelatin, collagen protein, agar, Bacterial cellulose from the high molecular polymer of property.
Further, described biological active matter is Oleum Blumeae Balsamiferae.
Further, described organic acid is one or more in formic acid, acetic acid, lactic acid and citric acid.
Further, described polyhydric alcohol is one or more in glycerol, Polyethylene Glycol, ethylene glycol and pentaerythritol.
A kind of preparation method of functional dressings is made up of following steps
1), get the high molecular polymer of anionic property, adding distil water is mixed with the solution of 5%-20%, after being dispersed into even colloidal liquid and polyhydric alcohol, biological activity mixing, remove impurity with 80 ~ 150 object net filtrations, obtain glue A;
2), get the high molecular polymer of cationic, adding distil water is mixed with the solution of 90%-98%, then add mass concentration be 1 ~ 5% organic acid be dispersed into even colloidal liquid, with 80 ~ 150 object net filtrations removing impurity, obtain glue liquid B;
3), by glue A and glue liquid B mixing, be 5 ~ 7 by triethanolamine, sodium hydroxide, potassium hydroxide adjust ph, obtain slurry;
4), by slurry through vacuumizing and defoaming, curtain coating in circulation base band, be applied to non-woven fabrics base material or PU film surface obtain insoluble film through 50 DEG C of-80 DEG C of hot air dryings, through section composite steps obtain.
Further, above-mentioned mixing disposed slurry can be directly used in wound surface coating or sinus wound area after subpackage without masking.
Beneficial effect of the present invention: a kind of functional dressings tool for the preparation of medical wound dressing provided by the invention has the following advantages: (1) its natural polymers adopted, good biocompatibility, effectively can absorb the transudate of wound tissue, liquid absorption about 3 ~ 20 times, thus effectively prevent wound surface hydrops, keep wound surface moistening, for wound provides a good healing environment, and make dressing be easy to peel off and change; (2) Oleum Blumeae Balsamiferae be scattered in polysaccharide film is natural components, nontoxic to people, non-stimulated to skin, has certain antibacterial ability, has a broad antifungal spectrum and having no drug resistance, and can reduce dressing change frequency, protect from infection, particularly favourable to wound the wounded of antibiotic allergy; (3) can tissue regeneration be promoted, reduce inflammatory reaction, make wound surface recovery period shift to an earlier date 5 ~ 6 days; Therefore be prepared into that medical wound dressing is easy to use, simple application is extensive, be applicable to the preparation that wound surface amasss larger medical dressing.
Application test with this nursing dressing:
Test sample: select rat to make laboratory animal, shaves rat back test block hair and removes, and is often only standardizedly about 12mm, the wound of deeply about 1.5mm, sample of doing experiment.
Process of the test: test is divided into matched group and processed group two groups, often organize 10 test samples, respectively the dressing chosen in controlled trial and process test group is covered in the wound surface of test sample, the wound detumescence situation of viewing test sample within the observation period of 10 days.
Controlled trial: adopt in advance at 1%(wt.%) the monolayer cotton cloth that soaked in the western quinoline solution of furan makes dressing.
Process test: adopt Wound care dressing in the embodiment of the present invention (2).Result of the test: list in table 1.Process test compared with controlled trial, in process test, the obvious swelling time of test sample on average can shift to an earlier date 3 ~ 5 days than controlled trial, and this result shows: Wound care dressing provided by the invention has good antiinflammatory performance.
Detailed description of the invention
In order to understand the present invention better, illustrate content of the present invention further below in conjunction with embodiment, but content of the present invention is not only confined to the following examples.
The deacetylation of the chitosan used in following embodiment is 40 ~ 80%.
The preparation of functional dressings film: the proportioning of each component is by weight: the high molecular polymer 2% ~ 6% of cationic; The high molecular polymer 2% ~ 6% of anionic property; Polyhydric alcohol 2.8% ~ 10%; Plants essential oil 0.2% ~ 2%; Organic acid 0.5% ~ 3%.; Water 4% ~ 92%
Embodiment 1
Take 10g sodium alginate, 5g glycerol, add deionized water 100mL, stir, obtain even viscous liquid, then obtain glue A through 100 order nylon wire press filtrations; Separately get ethyl chitosan 3g, add water 100 mL, lactic acid 2g stirring and dissolving, then after adding Oleum Blumeae Balsamiferae 0.2 stirring, obtain glue liquid B through 100 object nylon wire press filtrations.Glue A, glue liquid B are uniformly mixed, vacuumizing and defoaming, then extrudes with extruder, coats stainless steel band or coats fabric face, 60 DEG C of hot air dryings obtain antibacterial heal-promoting gel film, or first coated obtains the good dressing membrane of intensity through 60 DEG C of hot air dryings again in nonwoven cloth cover.
Embodiment 2
Take gelatin 10g, 6g glycerol, add deionized water 100mL, stir, obtain even thick liquid; Glue A is obtained through 100 order nylon wire press filtrations.Separately get chitosan 3g, add water 50 mL, lactic acid 1g stirring and dissolving, then after adding Oleum Blumeae Balsamiferae 0.5g stirring, as above method filters to obtain glue liquid B.By glue A, glue liquid B mixing and stirring, with triethanolamine adjust pH 5-7, vacuumizing and defoaming, then extrude with extruder, coat stainless steel band or appendix in fabric side, 60 DEG C of hot air dryings obtain antibacterial heal-promoting gel film, or first invest nonwoven cloth cover and obtain dressing membrane through 60 DEG C of hot air dryings again.
The film obtained with said method through section, then and forms by certain moisture-inhibiting, thin film backing that is ventilative and adherence force are superimposed the dressing of nursing for treating being used for open wound, burn surface, ulcer surface.
Embodiment 3
Take gelatin 8g, 6g glycerol, add deionized water 100mL, stir, obtain even thick liquid; Glue A is obtained through 100 order nylon wire press filtrations.Separately get chitosan 3g, add water 50 mL, lactic acid 1g stirring and dissolving, then after adding Oleum Blumeae Balsamiferae 0.7g stirring, as above method filters to obtain glue liquid B; By glue A, glue liquid B mixing and stirring, with triethanolamine adjust pH 5-7, vacuumizing and defoaming fill is for subsequent use in aluminium-plastic pipe, extrudes and be applied to wound surface during use.
Claims (8)
1. a functional dressings is characterized in that, is made up of the high molecular polymer of cationic and the high molecular polymer of anionic property and adjuvant, the high molecular polymer of cationic described by weight percentage, accounting 2% ~ 6%; The high molecular polymer of described anionic property, accounting 2% ~ 6%; Described adjuvant is that polyhydric alcohol, biological active matter, organic acid and moisture are made, and wherein polyhydric alcohol accounting is 2.8% ~ 10%, biological active matter is 0.2% ~ 2%, organic acid is 0.5% ~ 3% and moisture content 4% ~ 92%.
2. a kind of functional dressings according to claim 1, is characterized in that, described cationic high molecular polymer is chitosan, and described deacetylating degree of chitosan is 40 ~ 80% or hydroxyethyl chitosan.
3. a kind of functional dressings according to claim 1, is characterized in that, described the moon is one or more in carboxymethyl cellulose, xanthan gum, Algin, gelatin, collagen protein, agar, Bacterial cellulose from the high molecular polymer of property.
4. a kind of functional dressings according to claim 1, is characterized in that, described biological active matter is Oleum Blumeae Balsamiferae.
5. a kind of functional dressings according to claim 1, is characterized in that, described organic acid is one or more in formic acid, acetic acid, lactic acid and citric acid.
6. a kind of functional dressings according to claim 1, is characterized in that, described polyhydric alcohol is one or more in glycerol, Polyethylene Glycol, ethylene glycol and pentaerythritol.
7. the preparation method of a kind of functional dressings according to claim 1, is characterized in that, be made up of following steps
1), get the high molecular polymer of anionic property, adding distil water is mixed with the solution of 5%-20%, after being dispersed into even colloidal liquid and polyhydric alcohol, biological activity mixing, remove impurity with 80 ~ 150 object net filtrations, obtain glue A;
2), get the high molecular polymer of cationic, adding distil water is mixed with the solution of 90%-98%, then add mass concentration be 1 ~ 5% organic acid be dispersed into even colloidal liquid, with 80 ~ 150 object net filtrations removing impurity, obtain glue liquid B;
3), by glue A and glue liquid B mixing, be 5 ~ 7 by triethanolamine, sodium hydroxide, potassium hydroxide adjust ph, obtain slurry;
4), by slurry through vacuumizing and defoaming, curtain coating in circulation base band, be applied to non-woven fabrics base material or PU film surface obtain insoluble film through 50 DEG C of-80 DEG C of hot air dryings, through section composite steps obtain.
8. the preparation method of a kind of functional dressings according to claim 7, is characterized in that, above-mentioned mixing disposed slurry can be directly used in wound surface coating or sinus wound area after subpackage without masking.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510214862.9A CN104771779B (en) | 2015-04-30 | 2015-04-30 | A kind of functional dressings and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510214862.9A CN104771779B (en) | 2015-04-30 | 2015-04-30 | A kind of functional dressings and preparation method thereof |
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| Publication Number | Publication Date |
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| CN104771779A true CN104771779A (en) | 2015-07-15 |
| CN104771779B CN104771779B (en) | 2017-10-03 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105727360A (en) * | 2016-03-23 | 2016-07-06 | 成都超吉科技有限公司 | Biological material applied to operative skin incision and infectious and non-infectious wound surfaces and application thereof |
| CN106075533A (en) * | 2016-07-01 | 2016-11-09 | 赵艳丽 | A kind of antibacterial biological dressing and preparation method thereof |
| CN106380690A (en) * | 2016-09-05 | 2017-02-08 | 广东高乐玩具股份有限公司 | Novel modified polypropylene plastic and preparation method thereof |
| CN108210344A (en) * | 2016-12-21 | 2018-06-29 | 常州柚盾实业投资有限公司 | A kind of Modified Membrane cloth and preparation method thereof |
| CN108310462A (en) * | 2018-04-25 | 2018-07-24 | 信阳师范学院 | A kind of preparation method of hydroxyethyl chitosan plural gel |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN106075533A (en) * | 2016-07-01 | 2016-11-09 | 赵艳丽 | A kind of antibacterial biological dressing and preparation method thereof |
| CN106380690A (en) * | 2016-09-05 | 2017-02-08 | 广东高乐玩具股份有限公司 | Novel modified polypropylene plastic and preparation method thereof |
| CN108210344A (en) * | 2016-12-21 | 2018-06-29 | 常州柚盾实业投资有限公司 | A kind of Modified Membrane cloth and preparation method thereof |
| CN108310462A (en) * | 2018-04-25 | 2018-07-24 | 信阳师范学院 | A kind of preparation method of hydroxyethyl chitosan plural gel |
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