CN104768556A - 使用pde7抑制剂治疗成瘾和冲动控制障碍 - Google Patents

使用pde7抑制剂治疗成瘾和冲动控制障碍 Download PDF

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Publication number
CN104768556A
CN104768556A CN201380036048.1A CN201380036048A CN104768556A CN 104768556 A CN104768556 A CN 104768556A CN 201380036048 A CN201380036048 A CN 201380036048A CN 104768556 A CN104768556 A CN 104768556A
Authority
CN
China
Prior art keywords
formula
alkyl
addiction
pde7
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380036048.1A
Other languages
English (en)
Chinese (zh)
Inventor
G.A.德莫普罗斯
G.A.盖塔纳里斯
R.奇科乔波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omeros Corp
Original Assignee
Omeros Medical Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/835,607 external-priority patent/US9220715B2/en
Application filed by Omeros Medical Systems Inc filed Critical Omeros Medical Systems Inc
Priority to CN202210569437.1A priority Critical patent/CN114984229A/zh
Priority to CN202011054538.2A priority patent/CN112168972A/zh
Publication of CN104768556A publication Critical patent/CN104768556A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201380036048.1A 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍 Pending CN104768556A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202210569437.1A CN114984229A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍
CN202011054538.2A CN112168972A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261643611P 2012-05-07 2012-05-07
US61/643611 2012-05-07
US13/835607 2013-03-15
US13/835,607 US9220715B2 (en) 2010-11-08 2013-03-15 Treatment of addiction and impulse-control disorders using PDE7 inhibitors
PCT/US2013/039866 WO2013176877A2 (en) 2012-05-07 2013-05-07 Treatment of addiction and impulse-control disorders using pde7 inhibitors

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN202011054538.2A Division CN112168972A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍
CN202210569437.1A Division CN114984229A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍

Publications (1)

Publication Number Publication Date
CN104768556A true CN104768556A (zh) 2015-07-08

Family

ID=49624481

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201380036048.1A Pending CN104768556A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍
CN202210569437.1A Pending CN114984229A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍
CN202011054538.2A Pending CN112168972A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN202210569437.1A Pending CN114984229A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍
CN202011054538.2A Pending CN112168972A (zh) 2012-05-07 2013-05-07 使用pde7抑制剂治疗成瘾和冲动控制障碍

Country Status (10)

Country Link
EP (1) EP2846805B1 (enExample)
JP (1) JP2015521177A (enExample)
CN (3) CN104768556A (enExample)
AU (1) AU2013266793B2 (enExample)
CA (1) CA2871151C (enExample)
IN (1) IN2014DN10404A (enExample)
PL (1) PL2846805T3 (enExample)
RS (1) RS58381B1 (enExample)
SI (1) SI2846805T1 (enExample)
WO (1) WO2013176877A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109937038A (zh) * 2016-08-26 2019-06-25 田边三菱制药株式会社 双环式含氮杂环化合物

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9220715B2 (en) 2010-11-08 2015-12-29 Omeros Corporation Treatment of addiction and impulse-control disorders using PDE7 inhibitors
KR20220047894A (ko) 2010-11-08 2022-04-19 오메로스 코포레이션 Pde7 억제제를 사용한 중독 및 충동-조절 장애의 치료
CN119384295A (zh) * 2022-06-15 2025-01-28 松本真一 以纹状体纹状小体的多巴胺d1信号为靶点的强迫性障碍的药物疗法
KR20250048344A (ko) 2022-08-18 2025-04-08 미토디큐어 게엠베하 만성 피로, 탈진 및/또는 운동 불내성과 연관된 질환의 치료 및 예방을 위한 포스포디에스테라제-7 억제 활성을 갖는 치료제의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4810426B2 (ja) * 2004-07-01 2011-11-09 第一三共株式会社 Ｐｄｅ７阻害作用を有するチエノピラゾール誘導体
US20060183763A1 (en) * 2004-12-31 2006-08-17 Pfizer Inc Novel pyrrolidyl derivatives of heteroaromatic compounds
PL1928438T3 (pl) * 2005-09-26 2013-08-30 Avigen Inc Zastosowanie ibudilastu do leczenia uzależnień od środków odurzających
AU2008230710B2 (en) * 2007-03-27 2014-04-10 Omeros Corporation The use of PDE7 inhibitors for the treatment of movement disorders
US8637528B2 (en) * 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
ES2586433T3 (es) * 2007-04-11 2016-10-14 Omeros Corporation Composiciones y métodos para la profilaxis y el tratamiento de adicciones
FR2943673B1 (fr) * 2009-03-27 2013-03-29 Sanofi Aventis Applications therapeutiques de derives de quinazolinedione
FR2944282B1 (fr) * 2009-04-09 2013-05-03 Sanofi Aventis Derives de quinazolinedione, leur preparation et leurs diverses applications therapeutiques
KR20220047894A (ko) * 2010-11-08 2022-04-19 오메로스 코포레이션 Pde7 억제제를 사용한 중독 및 충동-조절 장애의 치료

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109937038A (zh) * 2016-08-26 2019-06-25 田边三菱制药株式会社 双环式含氮杂环化合物

Also Published As

Publication number Publication date
CA2871151C (en) 2019-03-26
SI2846805T1 (sl) 2019-04-30
PL2846805T3 (pl) 2019-05-31
AU2013266793B2 (en) 2016-08-04
EP2846805A2 (en) 2015-03-18
CN114984229A (zh) 2022-09-02
WO2013176877A3 (en) 2015-06-18
RS58381B1 (sr) 2019-04-30
IN2014DN10404A (enExample) 2015-08-14
CA2871151A1 (en) 2013-11-28
JP2015521177A (ja) 2015-07-27
EP2846805A4 (en) 2016-08-10
CN112168972A (zh) 2021-01-05
AU2013266793A1 (en) 2014-11-27
EP2846805B1 (en) 2018-11-21
WO2013176877A2 (en) 2013-11-28

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Legal Events

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C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150708

RJ01 Rejection of invention patent application after publication