CN104758614A - Tincture for treating acnes and preparation method of tincture - Google Patents

Abstract

The invention discloses a tincture for treating acnes and a preparation method of the tincture. The active ingredients of the tincture are prepared from the following raw materials: golden cypress, wormwood, lotus leaf, gentian, daylily, castor, herb of sessile alternanthera, white muscardine silkworm, weeping forsythia capsule, thin-petiole grass fern, puncturevine caltrop fruit, shortpetal daphne, Japanese saussurea herb, mustela eversmanni lesson, lamiophlomis rotata kudo, sophora japonical, dragon's bone, manyinflorescenced sweetvetch root, ginkgo, common bletilla tuber, aloe, honey and olive oil. The tincture has the effects of clearing heat and expelling damp, diminishing swelling and detoxifying, activating blood and dispelling the wind, and fading acnes and promoting tissue regeneration, and is convenient to carry, convenient to use, simple in treatment way, accurate in acne treatment effect, and high in effective rate; the acnes do not relapse after being cured; and a pharmacologic test proves that the tincture has no toxic and side effects and can be applied safely.

Description

Tincture of a kind of Acne treatment and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines, be specifically related to tincture of a kind of Acne treatment and preparation method thereof.

Background technology

Acne is a kind of pilosebaceous chronic inflammatory disease; be apt to occur in the position that the hebetic face of men and women and thoracic dorsal sebaceous gland are abundant; the course of disease often slowly delays even decades more than ten years; clinically with the acne of face, pimple, pustule or tuberosity, cyst for feature; easy recurrent exerbation; and easily stay cicatrix, even disfeature.

The factors such as the generation of acne is main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the level of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug and micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.

Primary disease is called " rosacea caused by lung-wind " by the traditional Chinese medical science, has again numerous name of disease such as " Zha ", " pimples ", " wine Zha ", " acne ", " flour slag ", " whelk ", " efflorescence skin ulcer ", " acne vulgaris " in ancient literature.About the etiology and pathogenesis of primary disease, be recorded in the earliest " a Plain Questions vital QI of the body connecting with natural QI opinion section ": " exposure to the wind after sweating due to overstrain, invasion of pathogenic cold is Zha, and strongly fragrant is Cuo." teacher Yang Muxiang thinks, acne is mainly in Head And Face and chest and back, and Head And Face is the remittance of all sun, and carry on the back as sun, governor vessel follows row part, and yang-energy converges, caused by therefore the many Yin Yangre of acne win partially.From the cacosplanchnia position involved by primary disease, lung governing skin and hair, lung meridian is hot and suffocating, feels ailment said due to cold or exposure again, then send out acne; The lung and the large intestine being interior-exteriorly related, large intestine conduction mistake department, affects lung qi a surname respectful, easily raw acne; " Plain Questions the most pure virginity will be discussed greatly " is called it " all sufferings skin ulcers, all belong to the heart ", the heart matches fire, and in burning hot inflammation, flaming up of heart-fire women's head-ornaments, can send out acne; If surfeit delicious food, impairing the spleen and stomach, transporting and transforming function of the spleen and stomach is not normal, interior raw phlegm-damp, damp-stagnancy heat-transformation, damp-heat and virulent fire produced from the interior, or the wet hot phlegm stasis of blood stagnates and can cause acne; Disorder of emotion, stagnation of QI due to depression of the liver, face that stagnated QI transforming into fire is had no regard for something's face, can send out acne.As can be seen here, though acne is in face, its internal organs such as morbidity and lung, the heart, liver, spleen, stomach, large intestine all have substantial connection.

At present, medically effective Therapeutic Method be there is no to acne, the medicines such as doctor trained in Western medicine many employings antibiotic, gonadal hormone, retinoid carry out Acne treatment, though there is certain effect, but cure the symptoms, not the disease, the intrinsic factor bringing out acne still exist, and there is certain side effect with these chemotherapys, the course for the treatment of is long, easily recurs.Although also there is the Chinese medicine preparation of some Acne treatments current Chinese medicine aspect, the heat and toxic materials clearing away medicine such as general multiplex Rhizoma Coptidis, Flos Lonicerae, Herba Taraxaci, though there is certain therapeutic effect, Time of Administration is long, and easily recurs, and does not fundamentally cure acne.

Summary of the invention

For solving the problem, the invention provides tincture of a kind of Acne treatment and preparation method thereof, tincture of the present invention has clearing heat and expelling damp, subduing swelling and detoxicating, promoting blood circulation by removing wind, effect of expelling pus and promoting granulation, to acne treatment determined curative effect, have no side effect, effective percentage is high, fundamentally can cure acne, not easily recur after healing.

In order to solve the problem, technical scheme provided by the invention is:

A kind of tincture of Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 20-30 part, Artemisia absinihium L 15-25 part, Folium Nelumbinis 20-30 part, Radix Gentianae 15-35 part, Hemerocallis fulva L. 15-30 part, Semen Ricini 10-20 part, Herba Alternantherae sessilis 10-18 part, Bombyx Batryticatus 6-12 part, Fructus Forsythiae 5-11 part, Vittaria filipes christ． 4-10 part, Fructus Tribuli 4-10 part, short top top 3-7 part, Herba Saussuseae Japonicae 3-9 part, Mustela eversmanni lesson. 3-9 part, Radix Lamiophlomidis Rotatae 4-10 part, Cortex sophorae 3-9 part, Os Draconis 4-10 part, Radix Hedysari 4-10 part, Semen Ginkgo 5-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 4-10 part, Aloe 5-15 part, Mel 5-15 part, olive oil 6-12 part.

Further, a kind of tincture of Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 15-25 part, Artemisia absinihium L 18-22 part, Folium Nelumbinis 22-28 part, Radix Gentianae 20-30 part, Hemerocallis fulva L. 18-27 part, Semen Ricini 12-18 part, Herba Alternantherae sessilis 12-16 part, Bombyx Batryticatus 8-10 part, Fructus Forsythiae 7-9 part, Vittaria filipes christ． 5-9 part, Fructus Tribuli 5-9 part, short top top 4-6 part, Herba Saussuseae Japonicae 4-8 part, Mustela eversmanni lesson. 4-8 part, Radix Lamiophlomidis Rotatae 6-8 part, Cortex sophorae 5-7 part, Os Draconis 6-8 part, Radix Hedysari 5-9 part, Semen Ginkgo 8-12 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 6-8 part, Aloe 8-12 part, Mel 8-12 part, olive oil 7-11 part.

Further, a tincture for Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 25 parts, Artemisia absinihium L 20 parts, 25 parts, Folium Nelumbinis, Radix Gentianae 25 parts, Hemerocallis fulva L. 22 parts, Semen Ricini 15 parts, Herba Alternantherae sessilis 14 parts, Bombyx Batryticatus 9 parts, Fructus Forsythiae 8 parts, Vittaria filipes christ． 7 parts, Fructus Tribuli 7 parts, short top top 5 parts, Herba Saussuseae Japonicae 6 parts, Mustela eversmanni lesson. 6 parts, Radix Lamiophlomidis Rotatae 7 parts, Cortex sophorae 6 parts, Os Draconis 7 parts, Radix Hedysari 7 parts, Semen Ginkgo 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, Aloe 10 parts, Mel 10 parts, 9 parts, olive oil.

The present invention also provides a kind of preparation method of tincture of Acne treatment, comprises the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 3-5 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 75% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.

Using method: every day the position suffering from acne is carried out clean after, by tincture obliterating of the present invention to affected part, obliterating 3-5 time every day.

Pharmacological action:

Cortex Phellodendri: bitter in the mouth, cold in nature.Return kidney, urinary bladder channel.Have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency; Artemisia absinihium L: bitter, cold, puckery.Enter spleen, stomach two warp.Heat clearing and damp drying, invigorating the stomach and promoting digestion, hemostasis unsting, control damp-heat syndrome, inappetence symptom.Control damp-heat syndrome, inappetence, as raw property insufficiency of stomach anorexia, pharyngolaryngitis, tonsillitis is that diligent happy sexuality is emitted, typhoid fever, hepatitis, and spleen inflammation is swollen, and pericarditis and arthralgia treat skin ulcer, eczema; Folium Nelumbinis: bitter in the mouth, property is put down.Return liver, spleen, stomach warp.Clearing away summer-heat and eliminating dampness, sending up the lucid YANG, cooling blood for hemostasis.Burnt FOLIUM NELUMBINIS then has the function of astringent therapy removing stasis to stop bleeding.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS is used for hemorrhage and puerperal blood faints; Radix Gentianae: bitter in the mouth, cold in nature.Return lung, Liver Channel.Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, eczema pruritus, liver-fire conjunctival congestion, Hiccough and deaf, hypochondriac pain bitter taste, persistent erection of the penis, convulsion with spasms; Hemerocallis fulva L.: nature and flavor are sweet cool.Clearing away heat and promoting diuresis, cooling blood for hemostasis.For parotitis, jaundice, cystitis, hematuria, dysuria, agalactosis, menoxenia, epistaxis, has blood in stool.Mastitis are controlled in external; Semen Ricini: leaf: sweet, pungent, flat.Slightly poisonous.Root: light, micro-pungent is flat.Leaf: detumescence and drawing out poison, antipruritic.Control sore swollen toxin, fresh goods mashes external application; Control eczema to scratch where it itches, decoction being used as a lotion; Root: expelling wind and activating blood circulation, pain relieving is calm.For rheumatic arthritis, tetanus, epilepsy, schizophrenia.Tranquillizing to relieve muscle spasm, dispel the wind dissipating blood stasis.Control tetanus, epilepsy, rheumatalgia, traumatic injury stasis of blood pain, scrofula; Herba Alternantherae sessilis: bitter, cool.Heat clearing away, diuresis, removing toxic substances, cough is spitted blood, dysentery, discharging fresh blood stool, gonorrhea, swollen ulcer drug, eczema; Bombyx Batryticatus: Xin Xian, flat.Enter liver, lung, stomach warp.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Control apoplectic aphasia, infantile convulsion, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis; Fructus Forsythiae: bitter, cool.Enter the heart, liver, gallbladder meridian.Heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction." herbal classic ": main cold and heat, Mus flaccidity, scrofula, carbuncle malignant boil, goiter, stagnation of pathogenic heat; Vittaria filipes christ．: micro-puckery is flat.Enter liver, kidney two warp.Promoting blood circulation and stopping pain.For traumatic injury, bones and muscles pain, numb hand and foot person; Fructus Tribuli: pungent, bitter, tepor; Slightly poisonous.Return Liver Channel.Suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus; Short top top: pungent, micro-hardship is cool.Relaxing muscles and tendons and activating QI and blood in the collateral, wind-expelling pain-stopping, antipyretic preventing the attack (or recurrence) of malaria.Traumatic injury, rheumatic arthritis, stomachache, flatulence is suffered from abdominal pain, cold, fever, malaria.This product is slightly poisonous, and consumption is unsuitable large; Herba Saussuseae Japonicae: bitter in the mouth, pungent, property is put down.Dispelling, collateral-activating, eliminating stasis to stop pain.Rheumatic arthralgia, traumatic injury.Be not taken by pregnant women; Mustela eversmanni lesson.: sweet in the mouth, warm in nature.GUIXIN, Liver Channel.Dispel the wind, spasmolytic, promoting blood circulation to remove obstruction in the collateral.Epilepsy, paralysis, hemiplegia; Radix Lamiophlomidis Rotatae: sweet in the mouth, hardship, property is put down.Return Liver Channel.Have promoting blood circulation and hemostasis, wind-expelling pain-stopping has effect.For traumatic injury, traumatic hemorrhage, rheumatic arthralgia, grasserie." Traditional Chinese Medicine in Sichuan will ": blood circulation promoting competent silt, pain relieving, circulation of qi promoting, detumescence, reunion of fractured tendons and bones.Control and get injured by a fall muscles and bones and diseases such as frustrating gas of spraining one's back; Cortex sophorae: " property of medicine opinion ": " bitter in the mouth, nontoxic." 2. " detailed outline ": " bitter, flat, nontoxic." expelling wind and removing dampness, reducing swelling and alleviating pain.Control in outside ailment said due to cold or exposure, orthotonus, numbness of the skin, calentura aphtha, ulcerative gingivitis, sore throat, discharging fresh blood stool, cellulitis, hemorrhoid, rotten skin ulcer.Pudendum is itched bitterly, soup, burning hot wound; Os Draconis: sweet puckery are flat.Enter the heart, liver, kidney, large intestine channel.Tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, seminal emission stranguria with turbid discharge, and tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time; Radix Hedysari: sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, blood deficiency and yellow complexion, and interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes; Semen Ginkgo: sweet in the mouth, micro-hardship, puckery, warm in nature, slightly poisonous.Have promote the production of body fluid, quench the thirst, the effect such as heat clearing away, can be used as medicine.There is effect of eliminating toxin and beautifying the skin, anti-acne simultaneously, be applicable to acne whelks patient.Often edible Semen Ginkgo, can YIN nourishing face nourishing antidebilitation old, expansion blood capillary, blood circulation promoting, make people's skin ruddy, in high spirits, life lengthening.Semen Ginkgo also has unobstructed blood vessel, improves brain function, hypermnesis ability, effect such as treatment senile dementia and cerebral blood supply insufficiency etc.; The Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth, sweet, puckery, cold in nature, returns lung, liver, stomach warp.There is astringing to arrest bleeding, the merit of detumescence and promoting granulation, for all cards of interior external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc.; Aloe: bitter, cold.Bactericidal action, antiinflammatory action, moistening beautification function, lets out effect under stomach invigorating, the heart tonifying effect of invigorating blood circulation, immunity and regeneration, immunity and antitumor action, Detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function.Pathogenic fire purging; Removing toxic substances; Blood stasis dispelling; Parasite killing.Argument is red; Constipation; Nebulousurine; Hematuria; Pediatric epilepsy scared; Infantile malnutrition; Burn and scald; Women's amenorrhea; Hemorrhoid; Scabies; Carbuncle furuncle and phyma poison; Traumatic injury; Mel: sweet in the mouth, property is put down.Return spleen, stomach, lung, large intestine channel.Gas fragrance, taste is extremely sweet.Mel has convergence, nutrition and Promotive union effect to wound surface, has lubricity to eliminate the phlegm and laxative effective.Harmonizing the spleen and stomach, relieving spasm to stop pain, nourishing the lung to arrest cough, loosening bowel to relieve constipation, skin moistening granulation promoting, removing toxic substances.The empty pain of main gastral cavity abdomen, xeropulmonary cough, dryness of the intestine constipation, conjunctival congestion, aphtha, ulcer being unable to heal, rubella pruritus, burn due to hot liquid or fire, rhagadia manus et pedis; Olive oil: the omega-fatty acid in olive oil can increase nitrogen oxide, can relax tremulous pulse, thus prevent the arterial injury because hypertension causes.Omega-fatty acid can also reduce hematoblastic stickiness in addition, allows platelet and Fibrinogen not easily be intertwined, blood circulation promoting; Olive oil is rich in the Squalene splendid with skin affinity and essential fatty acid, absorbs rapidly, effectively keeps skin elasticity with moist; Monounsaturated fatty acid contained abundant in olive oil and vitamin E, K, A, D etc. and phenols antioxidant, facial wrinkles can be eliminated, prevent skin aging, there is the effect such as skin or hair care and control hand and foot from chapping, be the cosmetics and skincare product that can " eat ", smear skin energy ultraviolet rays resistance with olive oil in addition and prevent skin carcinoma.

Primary disease is called " rosacea caused by lung-wind " by the traditional Chinese medical science, has again numerous name of disease such as " Zha ", " pimples ", " wine Zha ", " acne ", " flour slag ", " whelk ", " efflorescence skin ulcer ", " acne vulgaris " in ancient literature.About the etiology and pathogenesis of primary disease, be recorded in the earliest " a Plain Questions vital QI of the body connecting with natural QI opinion section ": " exposure to the wind after sweating due to overstrain, invasion of pathogenic cold is Zha, and strongly fragrant is Cuo." " Plain Questions the most pure virginity will be discussed greatly " call it " all sufferings skin ulcers, all belong to the heart ", the heart matches fire, in burning hot inflammation, flaming up of heart-fire women's head-ornaments, can send out acne; If surfeit delicious food, impairing the spleen and stomach, transporting and transforming function of the spleen and stomach is not normal, interior raw phlegm-damp, damp-stagnancy heat-transformation, damp-heat and virulent fire produced from the interior, or the wet hot phlegm stasis of blood stagnates and can cause acne; Disorder of emotion, stagnation of QI due to depression of the liver, face that stagnated QI transforming into fire is had no regard for something's face, can send out acne.So the present inventor thinks the many and eating and drinking without temperance of primary disease, the pungent and delicious food savoury of surfeit, feels exopathogen again, make hair follicle inaccessible, interior-heat must not reach thoroughly, causes heat in blood to be accumulate and steams in face, or lung meridian intrinsic heat, diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, or damp-heat in the spleen and stomach, inside accumulate and steam in face and formed, when Acne treatment with clearing heat and expelling damp, subduing swelling and detoxicating, promoting blood circulation by removing wind, expelling pus and promoting granulation is the rule for the treatment of.

Fang Zhong, Cortex Phellodendri, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Hemerocallis fulva L. is monarch drug altogether, effect that Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging removes steaming, detoxification sore treatment, Artemisia absinihium L energy heat clearing and damp drying, invigorating the stomach and promoting digestion, hemostasis unsting, Folium Nelumbinis clearing away summer-heat and eliminating dampness, sending up the lucid YANG, cooling blood for hemostasis, Radix Gentianae heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire, Hemerocallis fulva L. clearing away heat and promoting diuresis, cooling blood for hemostasis, for the pathogeny of acne, all sufferings skin ulcers, all belong to fire, effect that five kinds of Chinese medicine plays clearing heat and expelling damp altogether, pathogenic fire purging removes steaming, Semen Ricini, Herba Alternantherae sessilis, Bombyx Batryticatus, Fructus Forsythiae is ministerial drug, and Semen Ricini tranquillizing to relieve muscle spasm, dispel the wind dissipating blood stasis, Herba Alternantherae sessilis energy clearing away heat and promoting diuresis, removing toxic substances, swollen ulcer drug, Bombyx Batryticatus expelling wind to relieve convulsion, dissipating phlegm and resolving masses, Fructus Forsythiae energy heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, four Chinese medicine plays effect of subduing swelling and detoxicating, dissipating phlegm and resolving masses altogether, stagnates carry out removing toxic substances and promoting subsidence of swelling for damp-heat and virulent fire produced from the interior, the wet hot phlegm stasis of blood, Vittaria filipes christ． energy promoting blood circulation and stopping pain in side, Fructus Tribuli suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight are antipruritic, short top top energy relaxing muscles and tendons and activating QI and blood in the collateral, wind-expelling pain-stopping, antipyretic preventing the attack (or recurrence) of malaria, Herba Saussuseae Japonicae dispelling, collateral-activating, eliminating stasis to stop pain, Mustela eversmanni lesson. suppressing liver-wind to relieve spasm, promoting blood circulation to remove obstruction in the collateral, Radix Lamiophlomidis Rotatae has promoting blood circulation and hemostasis, the effect of wind-expelling pain-stopping, for multiple sense exopathogen, make hair follicle inaccessible, interior-heat must not reach or lung meridian intrinsic heat thoroughly, diseases caused by exogenous pathogenic factor ailment said due to cold or exposure, effect of promoting blood circulation to remove obstruction in the collateral, wind-expelling pain-stopping played altogether by Six-element medicine, Cortex sophorae expelling wind and removing dampness, reducing swelling and alleviating pain, Os Draconis tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing, Radix Hedysari invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, Semen Ginkgo has promoting the production of body fluid to quench thirst, heat clearing away, eliminating toxin and beautifying the skin, effect of anti-acne, the Pseudobulbus Bletillae (Rhizoma Bletillae) has astringing to arrest bleeding, the merit of detumescence and promoting granulation, Aloe has sterilization antiinflammatory, moistening beauty treatment, removing toxic substances, antidotal effect, Mel has convergence to wound surface, nutrition and Promotive union effect, energy harmonizing the spleen and stomach, relieving spasm to stop pain, nourishing the lung to arrest cough, loosening bowel to relieve constipation, skin moistening granulation promoting, coordinating the actions of various ingredients in a prescription, olive oil energy blood circulation promoting, effective maintenance skin elasticity is with moist, this a few taste medicine share and can reach reducing swelling and alleviating pain, expelling pus and promoting granulation, effect of bactericidal antiphlogistic, altogether for making medicine.Effect of clearing heat and expelling damp, subduing swelling and detoxicating, promoting blood circulation by removing wind, expelling pus and promoting granulation played altogether by all medicines above, dispels exopathogen, and make hair follicle open, interior heat penetration reaches, and causes heat in blood to be distributed by face, treating both the principal and secondary aspects of a disease, thus reaches the object of Acne treatment.

In preparation method of the present invention, employing ethanol stirs the effective ingredient in ultrasonic lixiviate Chinese medicine, Chinese medicine is subject to hyperacoustic mechanical shearing effect in leaching process, cell is more easily broken, effective ingredient wherein is more easily precipitated, filter filtering residue continuation with soak by water once, the effective ingredient in Chinese medicine can be extracted to a greater extent, makes tincture of the present invention have higher curative effect.

The invention has the beneficial effects as follows:

(1) the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription meets theory of Chinese medical science and Pharmacopoeia of People's Republic of China requirement, to human non-toxic's side effect, all former spices are coordinated gram at utmost to play drug effect according to the principle of monarch together, play clearing heat and expelling damp altogether, subduing swelling and detoxicating, promoting blood circulation by removing wind, the merit of expelling pus and promoting granulation, reaches the object of Acne treatment;

(2) in preparation method of the present invention, employing ethanol stirs the effective ingredient in ultrasonic lixiviate Chinese medicine, Chinese medicine is subject to hyperacoustic mechanical shearing effect in leaching process, cell is more easily broken, and effective ingredient wherein is more easily precipitated, the filtering residue continuation of filtration with soak by water once, effective ingredient in Chinese medicine can be extracted to a greater extent, make tincture of the present invention have higher curative effect, and preparation method is simple, easily implements;

(3) mass fraction of the ethanol in tincture of the present invention is 75%, the ethanol of this mass fraction has the highest bactericidal effect, olive oil energy blood circulation promoting, after this tincture acts on affected part, the effective ingredient of medicine infiltrates human body fast, fully by pore, reaches clearing heat and expelling damp, subduing swelling and detoxicating, promoting blood circulation by removing wind, the effect of expelling pus and promoting granulation.This tincture is convenient to carry with, easy to use, and treatment means is simple, and determined curative effect, effective percentage is high, not easily recurs after healing, proves through drug test, and tincture of the present invention has no side effect, and can relievedly use.

Detailed description of the invention

Below in conjunction with embodiments of the invention, technical scheme of the present invention is clearly and completely described.

Embodiment 1

A tincture for Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 20 parts, Artemisia absinihium L 15 parts, 20 parts, Folium Nelumbinis, Radix Gentianae 15 parts, Hemerocallis fulva L. 15 parts, Semen Ricini 10 parts, Herba Alternantherae sessilis 10 parts, Bombyx Batryticatus 6 parts, Fructus Forsythiae 5 parts, Vittaria filipes christ． 4 parts, Fructus Tribuli 4 parts, short top top 5 parts, Herba Saussuseae Japonicae 3 parts, Mustela eversmanni lesson. 3 parts, Radix Lamiophlomidis Rotatae 4 parts, Cortex sophorae 3 parts, Os Draconis 4 parts, Radix Hedysari 4 parts, Semen Ginkgo 5 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 4 parts, Aloe 5 parts, Mel 5 parts, 6 parts, olive oil.

The preparation method of the tincture of described Acne treatment, comprises the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 3 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 65% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.

Embodiment 2

A tincture for Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 30 parts, Artemisia absinihium L 25 parts, 30 parts, Folium Nelumbinis, Radix Gentianae 35 parts, Hemerocallis fulva L. 30 parts, Semen Ricini 20 parts, Herba Alternantherae sessilis 18 parts, Bombyx Batryticatus 12 parts, Fructus Forsythiae 11 parts, Vittaria filipes christ． 10 parts, Fructus Tribuli 10 parts, short top top 13 parts, Herba Saussuseae Japonicae 9 parts, Mustela eversmanni lesson. 9 parts, Radix Lamiophlomidis Rotatae 10 parts, Cortex sophorae 9 parts, Os Draconis 10 parts, Radix Hedysari 10 parts, Semen Ginkgo 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Aloe 15 parts, Mel 15 parts, 12 parts, olive oil.

The preparation method of the tincture of described Acne treatment, comprises the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 4 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 75% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.

Embodiment 3

A tincture for Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 15 parts, Artemisia absinihium L 18 parts, 22 parts, Folium Nelumbinis, Radix Gentianae 20 parts, Hemerocallis fulva L. 18 parts, Semen Ricini 12 parts, Herba Alternantherae sessilis 12 parts, Bombyx Batryticatus 8 parts, Fructus Forsythiae 7 parts, Vittaria filipes christ． 5 parts, Fructus Tribuli 5 parts, short top top 7 parts, Herba Saussuseae Japonicae 4 parts, Mustela eversmanni lesson. 4 parts, Radix Lamiophlomidis Rotatae 6 parts, Cortex sophorae 5 parts, Os Draconis 6 parts, Radix Hedysari 5 parts, Semen Ginkgo 8 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 6 parts, Aloe 8 parts, Mel 8 parts, 7 parts, olive oil.

The preparation method of the tincture of described Acne treatment, comprises the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 5 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 75% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.

Embodiment 4

A tincture for Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 25 parts, Artemisia absinihium L 22 parts, 28 parts, Folium Nelumbinis, Radix Gentianae 30 parts, Hemerocallis fulva L. 27 parts, Semen Ricini 18 parts, Herba Alternantherae sessilis 16 parts, Bombyx Batryticatus 10 parts, Fructus Forsythiae 9 parts, Vittaria filipes christ． 9 parts, Fructus Tribuli 9 parts, short top top 11 parts, Herba Saussuseae Japonicae 8 parts, Mustela eversmanni lesson. 8 parts, Radix Lamiophlomidis Rotatae 8 parts, Cortex sophorae 7 parts, Os Draconis 8 parts, Radix Hedysari 9 parts, Semen Ginkgo 12 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8 parts, Aloe 12 parts, Mel 12 parts, 11 parts, olive oil.

The preparation method of the tincture of described Acne treatment, comprises the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 4 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 75% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.

Embodiment 5

A tincture for Acne treatment, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 25 parts, Artemisia absinihium L 20 parts, 25 parts, Folium Nelumbinis, Radix Gentianae 25 parts, Hemerocallis fulva L. 22 parts, Semen Ricini 15 parts, Herba Alternantherae sessilis 14 parts, Bombyx Batryticatus 9 parts, Fructus Forsythiae 8 parts, Vittaria filipes christ． 7 parts, Fructus Tribuli 7 parts, short top top 9 parts, Herba Saussuseae Japonicae 6 parts, Mustela eversmanni lesson. 6 parts, Radix Lamiophlomidis Rotatae 7 parts, Cortex sophorae 6 parts, Os Draconis 7 parts, Radix Hedysari 7 parts, Semen Ginkgo 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, Aloe 10 parts, Mel 10 parts, 9 parts, olive oil.

The preparation method of the tincture of described Acne treatment, comprises the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 4 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 75% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.

Embodiment 6

Acute dermal toxicity is tested

This Traditional Chinese medicine tincture preparation gives healthy adult rat by Ministry of Public Health " cosmetics health specification " (2007 editions) " acute dermal toxicity once limit the quantity test method(s) " per os, body weight 180-220g, 20, male and female half and half, one time percutaneous smears dosage 5000mg/kg body weight, observe 14 days, test rat body situation, diet, drinking-water, body weight increase all normal, there are not obvious intoxicating phenomenon and the phenomena of mortality, place's post mortem Non Apparent Abnormality, judges that this Chinese medicine composition is to the nontoxic level in the true border of rat acute Oral toxicity.

Embodiment 7

Clinical experimental study:

(1) clinical data

For investigating clinical efficacy and the safety of Chinese medicine composition of the present invention further, choose 180 routine patients with acne and clinical observation is carried out to the curative effect of Traditional Chinese medicine tincture preparation of the present invention, patient age 15-30 one full year of life, men and women, and patient can complete test, and sign written informed consent voluntarily before on-test.Treat patient in first 30 days and do not use the oral medicine or photosensitive drug that too primary disease is relevant.

(2) diagnostic criteria

Canonical reference Pill Sburv and international improvement acne staging, Zhao distinguish show " clinical dermatology " second edition.Acne vulgaris diagnostic criteria pubarche, falls ill, and is apt to occur in the flourishing position of face, upper breast and back sebaceous gland, symmetrical.Skin lesion is pityriasis rubra pimple, black acne, pustule, tuberosity, cyst and cicatrix, with seborrhea, in chronic process.

(3) Therapeutic Method

Using method: every day the position suffering from acne is carried out clean after, by tincture obliterating of the present invention to affected part, obliterating 3-5 time every day.It within 10 days, is a course for the treatment of.

(4) efficacy assessment standard

Cure: inflamed papules, pustule, tuberosity and cyst disappear, skin lesion is fully recovered, and skin recovers normal, or only has a small amount of pigmentation;

Effective: inflamed papules, pustule, tuberosity and cyst are aobvious to be reduced, and skin lesion obviously alleviates, and skin recovers normal substantially;

Invalid: inflamed papules, pustule, tuberosity and cyst are without obvious change, or exacerbation of symptoms.

(5) therapeutic outcome

After the treatment of two courses for the treatment of, in 180 routine patients, cure 125 examples, take a turn for the better 53 examples, and do not heal 2 examples; Reach 69.4% through statistical analysis cure rate, total effective rate reaches 98.9%, and over the course for the treatment of, has no any untoward reaction or toxic and side effects, shows safe and effective for medication.

(6) model case

Case 1: Tan, man, 25 years old, patient facial region's acne had nearly ten years, and grain of rice size acne spreads all over frons and two cheeks, and color is red, and there are pus born of the same parents tip.Whole face goes out Chuck Steak, and consume oil greasy, maror, and long-term stool is uncomfortable, and two or three once.Often have halitosis, short-tempered, susceptible to lose temper due to restlessness, white and greasy fur, stringy pulse is fine and smooth.Once multiple washout, outer wiping, medicine for external application was used, equal DeGrain or recurrent exerbation.After taking a course for the treatment of of tincture of the present invention, pus born of the same parents obviously reduce, and skin lesion alleviates, and after continuing to take two courses for the treatment of of tincture of the present invention, pus born of the same parents disappear, and acne also disappears substantially, and skin lesion is fully recovered, and follows up a case by regular visits to and has no recurrence half a year.

Case 2: Zheng, female, 19 years old, patient facial region was covered with pimple, had pus born of the same parents, color is dark violet red, and micro-micro-pain of itching, can extrude milk yellow smectic thing during extruding, and part forms cicatrix, before and after companion's menstruation irregularly, through fore udder, lower abdominal distention pain, red tongue, has petechia, greasy fur, stringy and thready pulse.After taking a course for the treatment of of tincture of the present invention, pus born of the same parents obviously reduce, and skin lesion alleviates, and after continuing to take two courses for the treatment of of tincture of the present invention, pus born of the same parents disappear, and cicatrix also disappears substantially, and skin lesion is fully recovered, and follows up a case by regular visits to and does not recur for 1 year.

The above is the preferred embodiment of the present invention; its object is to allow person skilled in the art understand content of the present invention and to be implemented; should be understood that; for those skilled in the art; under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.

Claims (4)

1. the tincture of an Acne treatment, it is characterized in that, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 20-30 part, Artemisia absinihium L 15-25 part, Folium Nelumbinis 20-30 part, Radix Gentianae 15-35 part, Hemerocallis fulva L. 15-30 part, Semen Ricini 10-20 part, Herba Alternantherae sessilis 10-18 part, Bombyx Batryticatus 6-12 part, Fructus Forsythiae 5-11 part, Vittaria filipes christ． 4-10 part, Fructus Tribuli 4-10 part, short top top 3-7 part, Herba Saussuseae Japonicae 3-9 part, Mustela eversmanni lesson. 3-9 part, Radix Lamiophlomidis Rotatae 4-10 part, Cortex sophorae 3-9 part, Os Draconis 4-10 part, Radix Hedysari 4-10 part, Semen Ginkgo 5-15 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 4-10 part, Aloe 5-15 part, Mel 5-15 part, olive oil 6-12 part.

2. the tincture of a kind of Acne treatment as claimed in claim 1, it is characterized in that, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 15-25 part, Artemisia absinihium L 18-22 part, Folium Nelumbinis 22-28 part, Radix Gentianae 20-30 part, Hemerocallis fulva L. 18-27 part, Semen Ricini 12-18 part, Herba Alternantherae sessilis 12-16 part, Bombyx Batryticatus 8-10 part, Fructus Forsythiae 7-9 part, Vittaria filipes christ． 5-9 part, Fructus Tribuli 5-9 part, short top top 4-6 part, Herba Saussuseae Japonicae 4-8 part, Mustela eversmanni lesson. 4-8 part, Radix Lamiophlomidis Rotatae 6-8 part, Cortex sophorae 5-7 part, Os Draconis 6-8 part, Radix Hedysari 5-9 part, Semen Ginkgo 8-12 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 6-8 part, Aloe 8-12 part, Mel 8-12 part, olive oil 7-11 part.

3. the tincture of a kind of Acne treatment as claimed in claim 1, it is characterized in that, crude drug composition and the parts by weight thereof of making tincture effective ingredient comprise: Cortex Phellodendri 25 parts, Artemisia absinihium L 20 parts, 25 parts, Folium Nelumbinis, Radix Gentianae 25 parts, Hemerocallis fulva L. 22 parts, Semen Ricini 15 parts, Herba Alternantherae sessilis 14 parts, Bombyx Batryticatus 9 parts, Fructus Forsythiae 8 parts, Vittaria filipes christ． 7 parts, Fructus Tribuli 7 parts, short top top 5 parts, Herba Saussuseae Japonicae 6 parts, Mustela eversmanni lesson. 6 parts, Radix Lamiophlomidis Rotatae 7 parts, Cortex sophorae 6 parts, Os Draconis 7 parts, Radix Hedysari 7 parts, Semen Ginkgo 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 7 parts, Aloe 10 parts, Mel 10 parts, 9 parts, olive oil.

4. the preparation method of the tincture of a kind of Acne treatment as described in claim 1-3 any one, is characterized in that, comprise the following steps:

(1) by the Cortex Phellodendri of said ratio, Artemisia absinihium L, Folium Nelumbinis, Radix Gentianae, Semen Ricini, Herba Alternantherae sessilis, Fructus Forsythiae, Vittaria filipes christ．, Fructus Tribuli, Mustela eversmanni lesson., Radix Lamiophlomidis Rotatae, Cortex sophorae, Radix Hedysari grinds, cross 80 mesh sieves, then mixed-powder is mixed to get, then the ethanol that mass fraction is 75% is added, add ethanol and must measure not have mixed-powder to be as the criterion, load hermetic container soak and stir 3-5 days, stir speed (S.S.) is 100r/min, add ultrasonic in immersion process, every the ultrasonic 10min of 1h, ultrasonic power 250w, supersonic frequency 50KHz, then its medicinal liquid is filtered, collect filtering residue, obtain filtrate I,

(2) step (1) gained filtering residue is added 4 times of soak by water 1.5h, filter, obtain filtrate II;

(3) carry out micronizing by after the Hemerocallis fulva L. of said ratio, Bombyx Batryticatus, short top top, Herba Saussuseae Japonicae, Os Draconis, Pseudobulbus Bletillae (Rhizoma Bletillae) mixing, and cross 800 mesh sieves, obtain Chinese medicine ultra-fine powder;

(4), after fresh, undamaged Semen Ginkgo, Aloe being cleaned, common feeding in juice extractor is squeezed the juice, and is then filtered by juice 500 order grenadines, obtains mixing juice;

(5) the mixing juice that filtrate II filtrate I obtained for step (1), step (2) obtained, step (4) obtain fully mixes, then Mel, olive oil dispersing and dissolving is added, finally add Chinese medicine ultra-fine powder prepared by step (3), add mass fraction be 75% ethanol to the weight of feed liquid be 800 parts, and carry out homogenizing, obtain the tincture of described Acne treatment.