CN104740774A - Implantable self-powered cardioverter defibrillator - Google Patents

Implantable self-powered cardioverter defibrillator Download PDF

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Publication number
CN104740774A
CN104740774A CN201310731433.XA CN201310731433A CN104740774A CN 104740774 A CN104740774 A CN 104740774A CN 201310731433 A CN201310731433 A CN 201310731433A CN 104740774 A CN104740774 A CN 104740774A
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China
Prior art keywords
main body
generating main
defibrillator
cardioverter
self energizing
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CN201310731433.XA
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Chinese (zh)
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CN104740774B (en
Inventor
张�浩
曲丹
郎希龙
徐志云
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Second Military Medical University SMMU
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Second Military Medical University SMMU
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Abstract

The invention provides an implantable self-powered cardioverter defibrillator comprising a heart rhythm monitoring part, a pulse generator, a stimulation electrode, and a generating part. The generating part includes a generating body, an output unit, an electric energy storage unit, a fixing unit, and an encapsulation layer. The generating body, which is of a multilayer film structure, includes a piezoelectric material layer disposed in the middle of the generating body, and electrode layers disposed at the two sides of the piezoelectric material layer. The generating body is attached to the surface of the heart to collect the energy of the heart so as to produce electric energy. The output unit is connected with the electrode layers and used for outputting current to the electric energy storage unit. The electric energy storage unit is used for storing electric energy and supplying power to the heart rhythm monitoring part and the pulse generator. The fixing unit is disposed at the edge of the generating body. The encapsulation layer covers the surfaces of the generating body, the output unit, the electric energy storage unit and the fixing unit. The self-powered cardioverter defibrillator of the invention can be used forever without battery replacement.

Description

Implanted self energizing cardioverter-defibrillator
Technical field
The present invention relates to a kind of Implantable cardioverter-defibrillator, belong to medical instruments field.
Background technology
Along with the mankind deepen continuously to the understanding of various disease, increasing disease can adopt implantable electronic device to carry out diagnosing or treating.
For serious patients with ventricular arrhythmia, treat by Implantable cardioverter-defibrillator at present.But, cardioverter-defibrillator due to existing vivo implantation type uses battery as power supply, once the energy content of battery is exhausted, just need to change battery by operating mode, this both can cause physiological misery and psychological fear and anxiety to patient, also can increase the financial burden of patient and family thereof.
Summary of the invention
For solving the problem, the invention provides a kind of implanted self energizing cardioverter-defibrillator, it is characterized in that, comprising: rhythm of the heart monitoring portion, pulse generator, stimulating electrode and the Power Generation Section powered for described monitoring portion and described pulse generator.Power Generation Section comprises generating main body, output unit, energy storage unit, fixed cell and encapsulated layer.Wherein, generating main body is multi-layer film structure, comprises the piezoelectric material layer being positioned at described generating main center, and is positioned at the electrode layer of piezoelectric material layer both sides.Generating main body is by being attached at heart surface to gather cardiac energy for generation of electric energy.Output unit is connected with described electrode layer, exports to described energy storage unit for electric current generating main body produced.Energy storage unit is used for storage of electrical energy and powers for rhythm of the heart monitoring portion and pulse generator.Fixed cell is positioned at the edge of generating main body, for generating main body is fixed on visceral pericardium.Encapsulated layer is covered in the surface of generating main body, described output unit, described energy storage unit and described fixed cell.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, the shape of generating main body is tetragon, and output unit is positioned at the centre on two narrow limits of tetragon.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, the shape of generating main body is triangle, and output unit is positioned at leg-of-mutton three summits.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, the shape of generating main body is Long Circle.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, piezoelectric material layer contains nanoscale piezoelectric, and nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, piezoquartz is at least one deck zinc oxide nano-wire array.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, output unit has output electrode and current rectifying and wave filtering circuit.
In addition, in implanted self energizing cardioverter-defibrillator of the present invention, can also have such feature: wherein, encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
The effect of invention and effect
According to implanted self energizing cardioverter-defibrillator of the present invention, because generating main body is directly attached at heart surface, therefore, it is possible to effectively the contraction of heart and diastole are made nanoscale piezoelectric generation deformation, thus be converted into electric energy.As long as therefore heartbeat, the present invention can utilize the bioenergy of patient self and provide electric energy, eliminates the necessity using battery as power supply, solves after the energy content of battery is exhausted and needs operation to change the problem of battery.
In addition, because generating main body of the present invention adopts point fixing mode that electricity generation system is fixed on visceral pericardium, effectively can gather the energy that heart movement produces on the one hand, also can not produce significantly impact to the contraction of heart and diastole campaign on the other hand.
Because the present invention adopts nanoscale piezoelectric as generating main body, not only effectively the bioenergy in body can be converted into electric energy, and volume is small, is more suitable for et al. Ke.
In addition, because the present invention adopts the flexible macromolecule insulant of good biocompatibility to encapsulate, therefore generating main body and internal milieu can be isolated, also the pressure that the heart-shaped sell of one's property is raw effectively can be conducted to piezoelectric.
Further, because generating main body of the present invention is positioned at heart exterior, directly do not contact with blood, thus there is not the risk of thrombosis and apoplexy (myocardial infarction or cerebral infarction).
Accompanying drawing explanation
Fig. 1 is the generating main body of the implanted self energizing cardioverter-defibrillator of the embodiment of the present invention one is the schematic diagram of tetragon,
Fig. 2 is the partial section of the generating main body of the implanted self energizing cardioverter-defibrillator of the embodiment of the present invention one;
Fig. 3 is the generating main body of the implanted self energizing cardioverter-defibrillator of the embodiment of the present invention two is leg-of-mutton schematic diagram;
Fig. 4 is the generating main body of variation of the present invention is oblong schematic diagram; And
Fig. 5 is the circuit diagram of the embodiment of the present invention.
Detailed description of the invention
The detailed description of the invention of defibrillator of the present invention is described below in conjunction with accompanying drawing,
< embodiment one >
Fig. 1 is the generating main body of implanted self energizing cardioverter-defibrillator in embodiment 1 is the schematic diagram of tetragon, as shown in Figure 1, implanted self energizing cardioverter-defibrillator 20, has Power Generation Section 200, pulse generator 17 and stimulating electrode 18, and rhythm of the heart monitoring portion does not show in the drawings.Wherein, Power Generation Section 200 comprises generating main body 21, output unit, energy storage unit 16 and fixed cell 22.Generating main body 21 is rectangle, two narrow limits of rectangle respectively has a fixed cell 22, for generating main body is fixed on visceral pericardium with long axis direction along systaltic direction.Fixed cell 22 is made up of encapsulated layer, and the inside of fixed cell 22 does not have the electrification structure such as electrode or piezoelectric, therefore can not destroy the electrification structure of generating main body 21 when using suture to fix.Generating main body remainder except fixing with fixed cell is not fixed, and is beneficial in systaltic process, make generating main body better deformation can occur.Because generating main body have employed rectangle, and installation direction is consistent with systaltic direction, therefore can well gather the mechanical energy that heart contraction produces.
When implanting generating main body, heart is manifested by operating mode, generating main body arranged along systaltic direction and be sewn on visceral pericardium by fixed part, generating main body and visceral pericardium are fitted, and now generating electricity main body can along with the generation deformation of beating of heart.
Output unit comprises output electrode 14 and current rectifying and wave filtering circuit 15.Output electrode 14 exports to energy storage unit 16 for electric energy generating main body 21 produced, before energy storage unit 16, also there is current rectifying and wave filtering circuit 15, electric current for exporting output electrode 14 carries out rectifying and wave-filtering, thus makes the electric current of output more stable.Pulse generator 17 and monitoring portion (not shown) provide energy to carry out work by energy storage unit 16.When monitoring portion detects ventricular arrhythmia, pulse generator 17 can send electricity irritation by stimulating electrode 18 Cardiomyocytes, makes the rhythm of the heart recover normal.Fig. 2 is the sectional view of the generating main part of the implanted self energizing cardioverter-defibrillator of the embodiment of the present invention, as shown in Figure 2, generating main body 21 is multi-layer film structure, its central core is piezoelectric material layer 31, piezoelectric material layer 31 is made up of ZnO nanowire array, the both sides of piezoelectric material layer 31 are respectively electrode layer 32 and electrode layer 33, and electrode layer 32 and electrode layer 33 are connected with output electrode 14 (not shown) respectively.Encapsulated layer 34 is positioned at the outside of electrode layer 32 and electrode layer 33, and encapsulated layer 34 has good insulating properties and biocompatibility.
Fig. 5 is the circuit diagram of the embodiment of the present invention, as shown in Figure 5, generating main body 21 is connected with current rectifying and wave filtering circuit 15, the electric energy that generating main body 21 produces charges to energy storage unit 16 after current rectifying and wave filtering circuit 15, and energy storage unit 16 is for powering for the rhythm of the heart monitoring portion in electrical appliance and the present embodiment and pulse generator.
< embodiment two >
Fig. 3 is the leg-of-mutton implanted self energizing cardioverter-defibrillator schematic diagram of the embodiment of the present invention, as shown in Figure 3, the generating main body 12 of implanted self energizing cardioverter-defibrillator 11 of the present invention is triangle, leg-of-mutton each vertex position respectively has a fixed cell 13, output electrode 14 is connected with electrode layer (not showing in Fig. 3), current rectifying and wave filtering circuit 15 is connected with output electrode 14, and energy storage unit 16 is connected to current rectifying and wave filtering circuit 15 afterwards for storing the electric energy that Power Generation Section produces.
As shown in Figure 3, the shape of generating main body 12 is triangle, when being installed on visceral pericardium, utilizes the output unit 13 be positioned on an Atria summit generating main body 12 to be fixed on the visceral pericardium of myocardial wall.And each limit leg-of-mutton of the main body 12 that generates electricity is not fixed, both can not limit contraction and the diastole of heart, also contribute to piezoelectric material layer along with the motion generation deformation of heart thus produce electric energy.
Generating main body 12 is made into the energy that leg-of-mutton advantage is more to gather heartbeat, this is because not only have horizontal contraction and diastole in the process of heartbeat, also longitudinal contraction and diastole is had, when adopting leg-of-mutton shape, a leg-of-mutton summit is set to the direction towards the apex of the heart, and two other summit is set to parallel with the direction of heart cross-direction shrinkage, no matter being heart cross-direction shrinkage is like this longitudinal contraction, generating main body 12 all can be driven to be out of shape.Therefore the leg-of-mutton shape energy that can more utilize heartbeat to produce than the shape of tetragon.
After current rectifying and wave filtering circuit 15 is connected to output electrode 14, the electric current that generating main body 12 produces is stored in energy storage unit 16 after rectifying and wave-filtering, and energy storage unit 16 is miniature rechargeable battery.When rhythm of the heart monitoring portion (not showing in Fig. 3) detects arrhythmia, pulse generator 17 can control stimulating electrode 18 and send stimulating current and stimulate cardiac muscle, makes the rhythm of the heart recover normal.
< variation >
This variation is compared with embodiment one, and except the shape of the main body that generates electricity is except Long Circle, arranging of other is all identical.As shown in Figure 4, the shape of generating main body 42 is Long Circle, and on oblong two summits, place has fixed cell 41, and the shape of generating main body 42 is that oblong advantage is do not have sharp-pointed corner, contributes to alleviating the damage to heart.
Certainly, the shape of the generating main body of implanted self energizing cardioverter-defibrillator of the present invention can be various shape, is not limited only to triangle, tetragon and Long Circle in above-mentioned two embodiments.

Claims (9)

1. an implanted self energizing cardioverter-defibrillator, is characterized in that, comprising:
For monitoring the monitoring portion of cardiac electrical activity;
For generation of the pulse generator of electricity irritation;
The stimulating electrode be connected with described pulse generator; And
For the Power Generation Section that described monitoring portion and described pulse generator are powered,
Wherein, described Power Generation Section comprises generating main body, output unit, energy storage unit, fixed cell and encapsulated layer,
Described generating main body is multi-layer film structure, comprises the piezoelectric material layer being positioned at described generating main center, and is positioned at the electrode layer of piezoelectric material layer both sides, described generating main body by being attached at heart surface to gather the energy of heartbeat and to be converted into electric energy,
Described output unit is connected with described electrode layer, exports to described energy storage unit for electric current generating main body produced,
Described energy storage unit is used for storage of electrical energy and powers for described monitoring portion and described control part,
Described fixed cell is positioned at the edge of described generating main body, for generating main body is fixed on visceral pericardium,
Described encapsulated layer is covered in the surface of described generating main body, described output unit, described energy storage unit and described fixed cell.
2. implanted self energizing cardioverter-defibrillator as claimed in claim 1, is characterized in that:
Wherein, the shape of described generating main body is tetragon, and described fixed cell is positioned at the centre on two narrow limits of tetragon.
3. implanted self energizing cardioverter-defibrillator as claimed in claim 1, is characterized in that:
Wherein, the shape of described generating main body is triangle, and described fixed cell is positioned at leg-of-mutton three summits.
4. implanted self energizing cardioverter-defibrillator as claimed in claim 1, is characterized in that:
Wherein, the shape of described generating main body is Long Circle.
5. implanted self energizing cardioverter-defibrillator as claimed in claim 1, is characterized in that:
Wherein, described piezoelectric material layer contains nanoscale piezoelectric, and described nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
6. implanted self energizing cardioverter-defibrillator as claimed in claim 5, is characterized in that:
Wherein, described piezoquartz is at least one deck zinc oxide nano-wire array.
7. implanted self energizing cardioverter-defibrillator as claimed in claim 5, is characterized in that:
Wherein, described piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
8. implanted self energizing cardioverter-defibrillator as claimed in claim 1, is characterized in that:
Wherein, output unit has output electrode and current rectifying and wave filtering circuit.
9. implanted self energizing cardioverter-defibrillator as claimed in claim 1, is characterized in that:
Wherein, described encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
CN201310731433.XA 2013-12-26 2013-12-26 Implanted self energizing cardioverter-defibrillator Expired - Fee Related CN104740774B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101522A (en) * 2021-04-26 2021-07-13 上海联心医疗科技有限公司 Implantable cardiac pacing device
CN113117240A (en) * 2021-04-26 2021-07-16 上海联心医疗科技有限公司 Implanted bioenergy power supply system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101394807A (en) * 2005-12-12 2009-03-25 弗吉尼亚州立大学 Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials
US20100171394A1 (en) * 2008-07-06 2010-07-08 Glenn Richard A Energy harvesting for implanted medical devices
US20100228312A1 (en) * 2005-03-25 2010-09-09 Robert White Implantable Cardiac Motion Powered Piezoelectric Energy Source
CN204073105U (en) * 2013-12-26 2015-01-07 中国人民解放军第二军医大学 Implanted self energizing cardioverter-defibrillator

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100228312A1 (en) * 2005-03-25 2010-09-09 Robert White Implantable Cardiac Motion Powered Piezoelectric Energy Source
CN101394807A (en) * 2005-12-12 2009-03-25 弗吉尼亚州立大学 Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials
US20100171394A1 (en) * 2008-07-06 2010-07-08 Glenn Richard A Energy harvesting for implanted medical devices
CN204073105U (en) * 2013-12-26 2015-01-07 中国人民解放军第二军医大学 Implanted self energizing cardioverter-defibrillator

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113101522A (en) * 2021-04-26 2021-07-13 上海联心医疗科技有限公司 Implantable cardiac pacing device
CN113117240A (en) * 2021-04-26 2021-07-16 上海联心医疗科技有限公司 Implanted bioenergy power supply system

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