CN104740762A - Self-powered brain pacemaker - Google Patents
Self-powered brain pacemaker Download PDFInfo
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- CN104740762A CN104740762A CN201310731416.6A CN201310731416A CN104740762A CN 104740762 A CN104740762 A CN 104740762A CN 201310731416 A CN201310731416 A CN 201310731416A CN 104740762 A CN104740762 A CN 104740762A
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- main body
- generating main
- brain pacemaker
- self energizing
- storage unit
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Abstract
The invention provides a self-powered brain pacemaker which is characterized by comprising a pulse generator, a stimulation electrode, and a generating part. The generating part includes a generating body, an output unit, an electric energy storage unit, a fixing unit, and an encapsulation layer. The generating body, which is of a multilayer film structure, includes a piezoelectric material layer disposed in the middle of the generating body, and electrode layers disposed at the two sides of the piezoelectric material layer. The generating body is attached to the surface of the heart to collect the energy of the heart so as to produce electric energy. The output unit is connected with the electrode layers and used for outputting current produced by the generating body to the electric energy storage unit. The electric energy storage unit is used for storing electric energy and supplying power to the pulse generator. The fixing unit is disposed at the edge of the generating body and used for fixing the generating body to the epicardium. The encapsulation layer covers the surfaces of the generating body, the output unit, the electric energy storage unit and the fixing unit. The self-powered brain pacemaker of the invention can be used forever without battery replacement.
Description
Technical field
The present invention relates to a kind of self energizing brain pacemaker, belong to medical instruments field.
Background technology
Along with the mankind deepen continuously to the understanding of various disease, increasing disease can adopt implantable electronic device to carry out diagnosing or treating.
Wherein, implant the related neural of brain pacemaker by controlled motion in Stimulation of The Brain, suppress to cause the abnormal signal of Parkinsonian symptoms, alleviate symptoms such as even eliminating the trembling of patient, stiff and slow movement, make it recover original mobility and self-care ability.But the battery of brain pacemaker is 5 ~ 8 years, electricity must change the battery of brain pacemaker by operating mode after exhausting.This both can cause physiological misery and psychological fear and anxiety to patient, also can increase the financial burden of patient and family thereof.
Summary of the invention
For solving the problem, the invention provides a kind of self energizing brain pacemaker, it is characterized in that, comprising pulse generator, stimulating electrode and Power Generation Section.Power Generation Section comprises generating main body, output unit, energy storage unit, fixed cell and encapsulated layer.Wherein, generating main body is multi-layer film structure, comprises the piezoelectric material layer being positioned at generating main center, and is positioned at the electrode layer of piezoelectric material layer both sides, and generating main body is by being attached at heart surface to gather cardiac energy for generation of electric energy.Output unit is connected with electrode layer, exports to energy storage unit for electric current generating main body produced.Energy storage unit is used for storage of electrical energy also for pulse generator is powered.Fixed cell is positioned at the edge of generating main body, for generating main body is fixed on visceral pericardium.Encapsulated layer is covered in the surface of generating main body, output unit, energy storage unit and fixed cell.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, the shape of generating main body is tetragon, and fixed cell is positioned at the centre on two narrow limits of tetragon.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, the shape of generating main body is triangle, and fixed cell is positioned at leg-of-mutton three summits.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, the shape of generating main body is Long Circle.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, piezoelectric material layer contains nanoscale piezoelectric, and nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, piezoquartz is at least one deck zinc oxide nano-wire array.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, output unit has output electrode and current rectifying and wave filtering circuit.
In addition, in self energizing brain pacemaker of the present invention, can also have such feature: wherein, encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
The effect of invention and effect
According to self energizing brain pacemaker of the present invention, because generating main body is directly attached at heart surface, therefore, it is possible to effectively the contraction of heart and diastole are made nanoscale piezoelectric generation deformation, thus be converted into electric energy.As long as therefore heartbeat, the present invention can utilize the bioenergy of patient self and provide electric energy, eliminates the necessity using battery as power supply, solves after the energy content of battery is exhausted and needs operation to change the problem of battery.
In addition, because generating main body of the present invention adopts point fixing mode that electricity generation system is fixed on visceral pericardium, effectively can gather the energy that heart movement produces on the one hand, also can not produce significantly impact to the contraction of heart and diastole campaign on the other hand.
Because the present invention adopts nanoscale piezoelectric as generating main body, not only effectively the bioenergy in body can be converted into electric energy, and volume is small, is more suitable for et al. Ke.
In addition, because the present invention adopts the flexible macromolecule insulant of good biocompatibility to encapsulate, therefore generating main body and internal milieu can be isolated, also the pressure that the heart-shaped sell of one's property is raw effectively can be conducted to piezoelectric.
Further, because generating main body of the present invention is positioned at heart exterior, directly do not contact with blood, thus there is not the risk of thrombosis and apoplexy (myocardial infarction or cerebral infarction).
Accompanying drawing explanation
Fig. 1 is the generating main body of the self energizing brain pacemaker of the embodiment of the present invention one is the schematic diagram of tetragon;
Fig. 2 is the partial section of the generating main body of the self energizing brain pacemaker of the embodiment of the present invention one;
Fig. 3 is the generating main body of the self energizing brain pacemaker of the embodiment of the present invention two is leg-of-mutton schematic diagram;
Fig. 4 is the generating main body of variation of the present invention is oblong schematic diagram; And
Fig. 5 is the circuit diagram of the embodiment of the present invention one.
Detailed description of the invention
The detailed description of the invention of self energizing brain pacemaker of the present invention is described below in conjunction with accompanying drawing,
< embodiment one >
Fig. 1 is the generating main body of self energizing brain pacemaker in embodiment 1 is the schematic diagram of tetragon, and as shown in Figure 1, self energizing brain pacemaker 20 has Power Generation Section 200, pulse generator 17 and stimulating electrode 18.Wherein, Power Generation Section 200 comprises generating main body 21, output unit, energy storage unit 16, fixed cell 22 and encapsulated layer.Generating main body 21 is rectangle, two narrow limits of rectangle respectively has a fixed cell 22, for generating main body 11 is fixed on visceral pericardium with long axis direction along systaltic direction.When implanting generating main body, heart is manifested by operating mode, generating main body arranged along systaltic direction and be sewn on visceral pericardium by fixed part, generating main body and visceral pericardium are fitted, and now generating electricity main body can along with the generation deformation of beating of heart.
Fixed cell 22 is made up of encapsulated layer, and the inside of fixed cell 22 does not have the electrification structure such as electrode or piezoelectric, therefore can not destroy the electrification structure of generating main body 21 when using suture to fix.Because generating main body have employed rectangle, and installation direction is consistent with systaltic direction, therefore can well gather the mechanical energy that heart contraction produces.
Generating main body 21 remainder except fixing with fixed cell 22 is not fixed, and is beneficial in systaltic process, make generating main body 21 better deformation can occur.Output unit has output electrode 14 and current rectifying and wave filtering circuit 15, output electrode 14 exports to energy storage unit 16 for electric energy generating main body 21 produced, before energy storage unit 16, also there is current rectifying and wave filtering circuit 15, carry out rectifying and wave-filtering for the electric current exported output electrode 14.Energy storage unit 16 by supply of electrical energy to the pulse generator 17 of self energizing brain pacemaker.Stimulating electrode 18 implants intracranial, and pulse generator 17 produces high frequency electric pulse stimulates brain controlled motion related neural by stimulating electrode 18, suppresses the abnormal signal causing Parkinsonian symptoms.
Fig. 2 is the sectional view of the generating main part of the self energizing brain pacemaker of the embodiment of the present invention, generating main body 21 is multi-layer film structure, as shown in Figure 2, the central core of generating main body 21 is piezoelectric material layer 31, in the present embodiment, piezoelectric material layer 31 is made up of ZnO nanowire array, and the both sides of piezoelectric material layer 31 are respectively electrode layer 32 and electrode layer 33, and electrode layer 32 and electrode layer 33 are connected with output electrode 14 (not shown) respectively.Encapsulated layer 34 is positioned at the outside of electrode layer 32 and electrode layer 33, and encapsulated layer 34 has good insulating properties and biocompatibility.
Fig. 5 is the circuit diagram of the embodiment of the present invention, as shown in Figure 5, generating main body 21 is connected with current rectifying and wave filtering circuit 15, the electric energy that generating main body 21 produces charges to energy storage unit 16 after current rectifying and wave filtering circuit 15, and energy storage unit 16 is for powering for the pulse generator in electrical appliance and the present embodiment.
< embodiment two >
Fig. 3 is the Power Generation Section of the embodiment of the present invention is leg-of-mutton self energizing brain pacemaker schematic diagram, as shown in Figure 3, the generating main body 12 of self energizing brain pacemaker 11 of the present invention is triangle, leg-of-mutton each vertex position all has a fixed cell 13, output electrode 14 is connected with electrode layer (see figure 2), current rectifying and wave filtering circuit 15 is connected with output electrode 14, and energy storage unit 16 is connected to current rectifying and wave filtering circuit 15 afterwards for storing the electric energy that Power Generation Section produces.
Fig. 2 is the sectional view of the self energizing brain pacemaker of the embodiment of the present invention, as shown in Figure 2, the central core of generating main body is piezoelectric material layer 31, piezoelectric material layer 31 is made up of ZnO nanowire array, the both sides of piezoelectric material layer 31 are respectively electrode layer 32 and electrode layer 33, and electrode layer 32 is connected with output electrode 14 respectively with electrode layer 33.Encapsulated layer 34 is positioned at the outside of electrode layer electrode layer 32 and electrode layer 33.The surface of in fact whole self energizing brain pacemaker 11 is all coated with the encapsulated layer 34 of one deck good insulating, encapsulated layer 34 can use macromolecule polymeric material, and encapsulated layer 34 has good biocompatibility, make self energizing brain pacemaker 11 can not cause rejection when implanting.
As shown in Figure 3, the shape of generating main body 12 is triangle, when being installed on visceral pericardium, utilizes the fixed cell 13 be positioned on an Atria summit generating main body 12 to be fixed on the visceral pericardium of myocardial wall.And each limit leg-of-mutton of the main body 12 that generates electricity is not fixed, so both can not limit contraction and the diastole of heart, also contribute to piezoelectric material layer along with the motion generation deformation of heart thus produce electric energy.
Generating main body 12 is made into the energy that leg-of-mutton advantage is more to gather heartbeat, this is because not only have horizontal contraction and diastole in the process of heartbeat, also longitudinal contraction and diastole is had, when adopting leg-of-mutton shape, a leg-of-mutton summit is set to the direction towards the apex of the heart, and two other summit is set to parallel with the direction of heart cross-direction shrinkage, no matter being heart cross-direction shrinkage is like this longitudinal contraction, generating main body 12 all can be driven to be out of shape.Therefore the leg-of-mutton shape energy that can more utilize heartbeat to produce than the shape of tetragon.
Fixed cell 13 is extended in corresponding position by encapsulated layer and is formed, and damage piezoelectric material layer and electrode layer when sewing up, not containing piezoelectric and electrode material, therefore can be avoided in the inside of fixed cell 13.
Energy storage unit 16 by supply of electrical energy to the energy storage unit 16 of bioenergy self energizing brain pacemaker by supply of electrical energy to the pulse generator 17 of self energizing brain pacemaker.Pulse generator 17 produces the related neural of high frequency electric pulse by controlled motion in stimulating electrode 18 Stimulation of The Brain, suppresses the abnormal signal causing Parkinsonian symptoms.
< variation >
This variation is compared with embodiment one, and except the shape of the main body that generates electricity is except Long Circle, arranging of other is all identical.As shown in Figure 4, the shape of generating main body 42 is Long Circle, and on oblong two summits, place has fixed cell 41, and the shape of generating main body 42 is that oblong advantage is do not have sharp-pointed corner, contributes to alleviating the damage to heart.
Certainly, the shape of the generating main body of self energizing brain pacemaker of the present invention can be various shape, is not limited only to triangle, tetragon and Long Circle in above-mentioned two embodiments.
Claims (9)
1. a self energizing brain pacemaker, is characterized in that, comprising:
For generation of the pulse generator of electricity irritation;
The stimulating electrode be connected with this pulse generator; And
For the Power Generation Section that described pulse generator is powered,
Wherein, described Power Generation Section comprises generating main body, output unit, energy storage unit, fixed cell and encapsulated layer,
Described generating main body is multi-layer film structure, comprises the piezoelectric material layer being positioned at described generating main center, and is positioned at the electrode layer of piezoelectric material layer both sides, described generating main body by being attached at heart surface to gather the energy of heartbeat and to be converted into electric energy,
Described output unit is connected with described electrode layer, exports to described energy storage unit for electric current generating main body produced,
Described energy storage unit is used for storage of electrical energy and powers for described pulse generator,
Described fixed cell is positioned at the edge of described generating main body, for generating main body is fixed on visceral pericardium,
Described encapsulated layer is covered in the surface of described generating main body, described output unit, described energy storage unit and described fixed cell.
2. self energizing brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, the shape of described generating main body is tetragon, and described fixed cell is positioned at the centre on two narrow limits of tetragon.
3. self energizing brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, the shape of described generating main body is triangle, and described fixed cell is positioned at leg-of-mutton three summits.
4. self energizing brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, the shape of described generating main body is Long Circle.
5. self energizing brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, described piezoelectric material layer contains nanoscale piezoelectric, and described nanoscale piezoelectric is any one in piezoquartz, piezoelectric ceramics and organic piezopolymer.
6. self energizing brain pacemaker as claimed in claim 5, is characterized in that:
Wherein, described piezoquartz is at least one deck zinc oxide nano-wire array.
7. self energizing brain pacemaker as claimed in claim 5, is characterized in that:
Wherein, described piezoquartz, piezoelectric ceramics, organic piezopolymer can be the single or multiple lift structure of nanoscale piezoelectric.
8. self energizing brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, output unit has output electrode and current rectifying and wave filtering circuit.
9. self energizing brain pacemaker as claimed in claim 1, is characterized in that:
Wherein, described encapsulated layer is using the flexible macromolecule insulant of good biocompatibility as encapsulating material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310731416.6A CN104740762B (en) | 2013-12-26 | 2013-12-26 | Self energizing brain pacemaker |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310731416.6A CN104740762B (en) | 2013-12-26 | 2013-12-26 | Self energizing brain pacemaker |
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| Publication Number | Publication Date |
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| CN104740762A true CN104740762A (en) | 2015-07-01 |
| CN104740762B CN104740762B (en) | 2017-07-18 |
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| CN201310731416.6A Expired - Fee Related CN104740762B (en) | 2013-12-26 | 2013-12-26 | Self energizing brain pacemaker |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105233407A (en) * | 2015-10-19 | 2016-01-13 | 徐醒忠 | Bio-electrotherapy instrument and electrotherapy method thereof |
| CN108141154A (en) * | 2015-09-15 | 2018-06-08 | 密执安州立大学董事会 | Collection of energy without lead pacemaker |
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| CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
| US20100171394A1 (en) * | 2008-07-06 | 2010-07-08 | Glenn Richard A | Energy harvesting for implanted medical devices |
| US20100228312A1 (en) * | 2005-03-25 | 2010-09-09 | Robert White | Implantable Cardiac Motion Powered Piezoelectric Energy Source |
| CN204073100U (en) * | 2013-12-26 | 2015-01-07 | 中国人民解放军第二军医大学 | Self energizing brain pacemaker |
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2013
- 2013-12-26 CN CN201310731416.6A patent/CN104740762B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100228312A1 (en) * | 2005-03-25 | 2010-09-09 | Robert White | Implantable Cardiac Motion Powered Piezoelectric Energy Source |
| CN101394807A (en) * | 2005-12-12 | 2009-03-25 | 弗吉尼亚州立大学 | Self-sensing stents, smart materials-based stents, drug delivery systems, other medical devices, and medical uses for piezo-electric materials |
| US20100171394A1 (en) * | 2008-07-06 | 2010-07-08 | Glenn Richard A | Energy harvesting for implanted medical devices |
| CN204073100U (en) * | 2013-12-26 | 2015-01-07 | 中国人民解放军第二军医大学 | Self energizing brain pacemaker |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108141154A (en) * | 2015-09-15 | 2018-06-08 | 密执安州立大学董事会 | Collection of energy without lead pacemaker |
| CN105233407A (en) * | 2015-10-19 | 2016-01-13 | 徐醒忠 | Bio-electrotherapy instrument and electrotherapy method thereof |
| CN105233407B (en) * | 2015-10-19 | 2017-11-21 | 徐醒忠 | A kind of biological electro-therapeutic apparatus and its electrotherapeutic method |
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| CN104740762B (en) | 2017-07-18 |
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