CN104721671A - Traditional Chinese medicine for treating bronchiectasia - Google Patents

Abstract

The invention relates to the field of traditional Chinese medicine recipes in particular to traditional Chinese medicine for treating bronchiectasia. The traditional Chinese medicine is characterized by comprising, by weight, 15-20 parts of pyrola, 10-15 parts of Chinese holly leaf, 8-12 parts of herba ecliptae, 10-12 parts of rhizoma phragmitis, 10-15 parts of caulis perllae, 6-10 parts of stemona, 20-25 parts of physalis permviana, 6-8 parts of ternate buttercup root, 10-12 parts of cymbopogon distans, 12-15 parts of semen strychni, 15-20 parts of polygonum cuspidatum, 8-10 parts of aster, 12-16 parts of eriobotrya japonica, 6-10 parts of Maytenus diversifolius, 15-20 parts of vervain, 16-18 parts of kalmegh, 12-16 parts of adder's tongue herb, 3-5 parts of selfheal and 3-5 parts of fructus psoraleae. The preparation method of the traditional Chinese medicine includes: soaking the raw materials, decocting, and removing dregs to obtain filtrate. The traditional Chinese medicine is low in cost, high in curative effect, low in side effect, simple to prepare, short in curing time and less prone to relapse after curing, and medicinal efficacy can reach lesions directly.

Description

Treat bronchiectasic Chinese medicine

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically one is used for the treatment of bronchiectasic Chinese medicine.

Background technology

As everyone knows, bronchiectasis refers to the muscle of near-end median size bronchus due to tube wall and the destruction of elastic component, cause its segment dislocation exception, irreversibility expansion, distortion.Primary disease majority is acquired, is more common in child and youth.After being mostly secondary to acute and chronic respiratory tract infection and bronchial obstruction, patient has the medical histories such as young measles, pertussis or bronchopneumonia more.Clinical manifestation is mainly chronic cough, coughs a large amount of purulent sputum and (or) repeatedly spit blood.In recent years along with the appropriate treatment of acute and chronic respiratory tract infection, its sickness rate has minimizing trend.This disease is secondary to acute and chronic respiratory tract infection and bronchial obstruction mostly, and infection can cause obstruction, blocks and can cause again infecting, the two reciprocal causation.The common chronic cough of clinical symptoms, cough a large amount of purulent sputum and repeatedly spit blood, be more common in child and youth, male is more than women.Bronchiectasis is equivalent to Chinese medicine hemoptysis, lung abscess category.

In treatment, anti-inflammatory therapy.Anti-inflammatory therapy likely alleviates airway inflammation, helps the reparation of impaired airway mucus and fibre function.At present, anti-inflammatory effect research for low dose of Macrocyclolactone lactone kind medicine is more, especially has certain effect for diffuse panbronchiolitis and bronchiectasis, can alleviate Air way mucus secretion, destroy the biomembrane of Pseudomonas aeruginosa, reduce attack times.Erythromycin wherein, Roxithromycin, clarithromycin and azithromycin etc. all have certain effect to bronchiectasis.Though medicine can reach the effect controlling symptom, because toxic and side effects is large, patient is made to be difficult to accept.

Summary of the invention

Object of the present invention is exactly that provide one to treat bronchiectasic Chinese medicine, cost is low, curative effect is high, and toxic and side effects is little in order to overcome above-mentioned existing technical deficiency, and preparation is simple, and focus of going directly, healing time is short, not easily recurs after healing.

The technical scheme that the present invention solves the problems of the technologies described above employing is: one treats bronchiectasic Chinese medicine, it is characterized in that being made up of the crude drug of following weight portion, Herba Pyrolae 15 ~ 20, Folium Mahoniae 10 ~ 15, Herba Ecliptae 8 ~ 12, Rhizoma Phragmitis 10 ~ 12, Caulis Perillae 10 ~ 15, the Radix Stemonae 6 ~ 10, Calyx Seu Fructus Physalis 20 ~ 25, Radix Ranunculi Ternati 6 ~ 8, Herba Cymbopogonis 10 ~ 12, Semen Strychni 12 ~ 15, Rhizoma Polygoni Cuspidati 15 ~ 20, Radix Asteris 8 ~ 10, Folium Eriobotryae 12 ~ 16, Maytenus diversifolius (Hemsl.) Hou 6 ~ 10, Herba Verbenae 15 ~ 20, Herba Andrographis 16 ~ 18, Herba Ophioglossi 12 ~ 16, Spica Prunellae 3 ~ 5, Fructus Psoraleae 3 ~ 5, by medicinal for above-mentioned raw materials water soaking, to remove slag after decocting to obtain filtrate.

The invention has the beneficial effects as follows, cost is low, curative effect is high, and toxic and side effects is little, and preparation is simple, and focus of going directly, healing time is short, not easily recurs after healing.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

Herba Pyrolae, Folium Mahoniae, Herba Ecliptae, Rhizoma Phragmitis, Caulis Perillae, the Radix Stemonae, Calyx Seu Fructus Physalis, Radix Ranunculi Ternati, Herba Cymbopogonis, Semen Strychni, Rhizoma Polygoni Cuspidati, Radix Asteris, Folium Eriobotryae, Maytenus diversifolius (Hemsl.) Hou, Herba Verbenae, Herba Andrographis, Herba Ophioglossi, Spica Prunellae, Fructus Psoraleae is adopted to be that crude drug is prepared from.The every auxiliary medicine of its component (weight portion) is Herba Pyrolae 18, Folium Mahoniae 13, Herba Ecliptae 10, Rhizoma Phragmitis 11, Caulis Perillae 12, the Radix Stemonae 8, Calyx Seu Fructus Physalis 22, Radix Ranunculi Ternati 7, Herba Cymbopogonis 11, Semen Strychni 13, Rhizoma Polygoni Cuspidati 17, Radix Asteris 9, Folium Eriobotryae 14, Maytenus diversifolius (Hemsl.) Hou 8, Herba Verbenae 17, Herba Andrographis 17, Herba Ophioglossi 14, Spica Prunellae 4, Fructus Psoraleae 4.Get above-mentioned 19 kinds of crude drug, gross mass is 250g, at room temperature crude drug is added water to 900-1000ml, soak 4 hours, then boil slow fire with high heat and decoct to about 100-120 minute, remove slag to obtain filtrate about 200ml, medicinal residues add water 300-400ml again, decoct 30-40 minute, remove slag to obtain filtrate about 100ml, decocts medicine soup about 300ml for twice altogether.Every day, potion was oral at twice, each (medicine) being taken before meal about 150ml.

Herba Pyrolae of the present invention is used for rheumatic arthralgia, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera; Folium Mahoniae is mainly used in hectic fever due to deficiency of YIN, cough is spat blood, had a dizzy spell, soreness of the waist and knees; Herba Ecliptae can be restrained, stop blooding, effect of invigorating the liver and kidney; Rhizoma Phragmitis is used for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria; Caulis Perillae can reduce bronchial secretion, alleviates bronchospasm; The gentle lung qi of the Radix Stemonae, cough-relieving, parasite killing.Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma; Calyx Seu Fructus Physalis has the function of heat-clearing and toxic substances removing, antitussive diuresis; Radix Ranunculi Ternati dissipating phlegm and resolving masses, removing toxic substances and promoting subsidence of swelling, treatment Drug resistant pulmonary tubeculosis; Herba Cymbopogonis dampness removing, relieving cough and asthma.Cure mainly anemofrigid cold, cough and asthma; Semen Strychni has activating collaterals and eliminating stagnation, the effect of reducing swelling and alleviating pain; Rhizoma Polygoni Cuspidati has dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, effect of relieving cough and resolving phlegm; Radix Asteris warming the lung, the therapeutic method to keep the adverse QI flowing downwards, expectorant, cough-relieving.Control cough due to wind and cold's asthma, asthenia coughs vomiting bloody pus; Folium Eriobotryae antitussive, eliminate the phlegm, antiasthmatic effect; Maytenus diversifolius (Hemsl.) Hou is used for various wart disease, blood stasis dispersing and deswelling removing toxic substances, expectorant powder junction; Herba Verbenae has removing heat from blood, dissipating blood stasis, stimulates the menstrual flow, heat clearing away, removing toxic substances, antipruritic, anthelmintic, relieving distension effect; Herba Andrographis has heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain effect; Herba Ophioglossi heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis; Spica Prunellae has the effect of improving eyesight of relieving inflammation or internal heat, and can control conjunctival congestion and swelling pain, headache etc.; Fructus Psoraleae has the function of kidney invigorating and YANG supporting, spleen reinforcing stomach invigorating.

The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize, and its processing method is identical with embodiment one.

Embodiment	Herba Pyrolae	Folium Mahoniae	Herba Ecliptae	Rhizoma Phragmitis	Caulis Perillae	The Radix Stemonae	Calyx Seu Fructus Physalis	Radix Ranunculi Ternati	Herba Cymbopogonis	Semen Strychni	Rhizoma Polygoni Cuspidati	Radix Asteris	Folium Eriobotryae	Maytenus diversifolius (Hemsl.) Hou	Herba Verbenae	Herba Andrographis	Herba Ophioglossi	Spica Prunellae	Fructus Psoraleae
																				Two	15	15	8	12	10	10	20	8	10	15	15	10	12	10	15	18	12	5	3
Three	20	10	12	10	15	6	25	6	12	12	20	8	16	6	20	16	16	3	5
																				Four	19	12	9	11	12	7	21	7	11	13	18	9	13	7	19	17	13	4	4

Clinical data

1, data and method

1.1 physical data: during selecting in October ,-2014 in May, 2013, patient 64 example to our hospital, is bronchiectasis disease after diagnosing, wherein, man 36 example, female 28 example, slight 13 examples, moderate 30 example, severe 21 example.

1.2 diagnostic criteria

(1) chronic cough, a large amount of purulent sputum, repeatedly hemoptysis, blood volume are not etc., repeatedly there is pulmonary infection at same position, can with chronically infected poisoning symptom during Relapse rate, lung lesions audible moderate moist rales, some patients has drumstick finger (toe).

(2) x-ray inspection: increased bronchovascular shadows, disorder; Cystic bronchiectasis disease is cellular (curly hair shape) shade as seen.The air bronchogram that tomography is expanded as seen and is out of shape.

(3) Bronchography and the position of bronchiectasis, character and scope can be specified through bronchoscope selectivity radiography.

Severity Scaling:

A, mild: pathological changes limit office in lung section or more, but does not surmount a lobe of the lung.Cough white expectorant, occasionally have yellow sputum or sputum mixed with blood, except the concrete position of the clear and definite pathological changes of Bronchography, x-ray rabat only shows the non-specific texture weightening finish in local, and health check-up is often negative or only has Local Dry moist rales.Chinese medicine, Western medicine or collaborative treatment of Chinese and western medicines symptom very easy to control.

B, moderate: pathological changes can surmount a lobe of the lung, but be only limitted to side lung, cough, coughs up yellow sputum, time have spitting of blood in various degree, recurrent pulmonary infection, except the branch that Bronchography can determine concrete lung section, the diseased region that x-ray rabat also can show lung has cellular shade, auscultation can smell moist rales, even if through system anti-inflammatory treatment, local moist rales also not easily disappears completely, can take operative treatment.

C, severe: both sides lung all can lesions showed, fever and cough, coughs up yellow purulent sputum, corroles yellow green sputum when having a charrin's disease, sensation of oppression over the chest with shortness of breath, often there is drumstick finger (toe), have spitting of blood in various degree, even massive hemoptysis, recurrent pulmonary infection, Bronchography and chest x-ray rabat all can identification primary disease, and pulmonary function is the infringement of middle severe, loses opportunity of operation.

1.3 criterion of therapeutical effect

(1) effective: cough disappears, or alleviate more than 90%, cough up phlegm at below 20ml, expectorant by xanthochromia white, has no temperature, not spit blood or also without sputum mixed with blood, can participate in general work, spend orthobiosis, auscultation pulmonary respiratory murmur is clear, except a little moist rales in limited local, before sign returns to acute attack substantially.

(2) take a turn for the better: cough alleviates more than 30%, and expectorant has been down to 40% ~ 50% of former amount of expectoration, has no temperature, and does not spit blood, auscultation moist rales is own obviously to be reduced, the improvement of spirit muscle power.

(3) invalid: cough alleviates less than 30%, and amount of expectoration does not reduce, or reduce less than 40% ~ 50%, sign is with before treatment.

1.4 Therapeutic Method and therapeutic effect

64 routine patients use embodiment 1 medicament, every day, potion was oral at twice, each (medicine) being taken before meal about 150ml, within ten days, was a course for the treatment of, 1-5 the course for the treatment of of continuous treatment, further consultation, the routine patient of statistics discovery 57 is effective, and 4 routine patients are effective, 3 routine patients are invalid, 4 examples are effectively effective after 3-5 the course for the treatment of of patient's continual cures, and effective patient actively controls in the later stage, and half a year follows up a case by regular visits to without relapse.

2, model case

Case 1: journey, man, 56 years old, pathological changes surmounted the side lobe of the lung, and cough, coughs up yellow sputum, time have spitting of blood in various degree, recurrent pulmonary infection, the diseased region that x-ray rabat also can show lung has cellular shade, and auscultation can smell moist rales.Be diagnosed as bronchiectasis, using the pharmaceutical treatment of the embodiment of the present invention 1, ten days is a course for the treatment of, treats 2 courses for the treatment of continuously.After treating 1 course for the treatment of, alleviate more than 90%, cough up phlegm at below 20ml, expectorant is by xanthochromia white, and auscultation pulmonary respiratory murmur is clear, except a little moist rales in limited local, after 1 course for the treatment of of continual cure, before sign returns to outbreak substantially.

Case 2: Jiang, female, 46 years old, both sides lobe of the lung lesions showed, fever and cough, coughed up yellow purulent sputum, corroles yellow green sputum when having a charrin's disease, and sensation of oppression over the chest with shortness of breath, often has drumstick finger, spitting of blood, and pulmonary function be that middle severe is damaged.Using the pharmaceutical treatment of the embodiment of the present invention 1, ten days is a course for the treatment of, treats 5 courses for the treatment of continuously, further consultation, at the end of second course for the treatment of, cough alleviates more than 30%, and expectorant has been down to 40% ~ 50% of former amount of expectoration, has no temperature, do not spit blood, auscultation moist rales is own obviously to be reduced, the improvement of spirit muscle power.After adhering to three courses for the treatment of of treatment, cough alleviates more than 90%, coughs up phlegm at below 20ml, and expectorant by xanthochromia white, has no temperature, do not spit blood, can participate in general work, spends orthobiosis, before the clear sign of auscultation pulmonary respiratory murmur returns to disease substantially.

Claims (1)

1. the bronchiectasic Chinese medicine for the treatment of, it is characterized in that being made up of the crude drug of following weight portion: Herba Pyrolae 15 ~ 20, Folium Mahoniae 10 ~ 15, Herba Ecliptae 8 ~ 12, Rhizoma Phragmitis 10 ~ 12, Caulis Perillae 10 ~ 15, the Radix Stemonae 6 ~ 10, Calyx Seu Fructus Physalis 20 ~ 25, Radix Ranunculi Ternati 6 ~ 8, Herba Cymbopogonis 10 ~ 12, Semen Strychni 12 ~ 15, Rhizoma Polygoni Cuspidati 15 ~ 20, Radix Asteris 8 ~ 10, Folium Eriobotryae 12 ~ 16, Maytenus diversifolius (Hemsl.) Hou 6 ~ 10, Herba Verbenae 15 ~ 20, Herba Andrographis 16 ~ 18, Herba Ophioglossi 12 ~ 16, Spica Prunellae 3 ~ 5, Fructus Psoraleae 3 ~ 5, by medicinal for above-mentioned raw materials water soaking, to remove slag after decocting to obtain filtrate.