CN104721410A - Traditional Chinese medicinal composition for treating goatpox - Google Patents

Abstract

The invention discloses a traditional Chinese medicinal composition for treating goatpox. The traditional Chinese medicinal composition comprises goldthread, blackberry lily, the root of Chinese thorowax, gardenia, root-bark of Chinese wolfberry, the roots of kudzu vine, Chinese toon bark and mung bean. When the traditional Chinese medicinal composition is used for treatment, drug residues in sick bodies are avoided, medicinal cost is low, and requirements on pollution-free nuisanceless healthy food can be met. Through early-stage prevention and cure, spreading of illness can be inhibited, and risk of epidemic diseases can be reduced.

Description

A kind of herbal composite for the treatment of goatpox

Technical field

The present invention relates to technical field of Chinese medicines, specifically a kind of herbal composite for the treatment of goatpox.

Background technology

Sheep pox (Capripox, CP) comprise sheep pox, goatpox and cattle skin pimple sick, wherein the above two are the contagious disease caused with it sheep, goat by sheep pox virus (Sheeppox virus, SPPV) and goat capripoxvirus (Goatpox virus, GTPV) respectively.Ill domestic animal body temperature raises, and whole body just there will be pimple or tuberosity, vesicle, and more seriously, viscera is even dead, causes serious economic loss to world's sheep husbandry.OIE (OIE) is defined as the legal animal epidemic that must report, China is classified as a class zoonosis.

The pathogen of goatpox is goat capripoxvirus, and this virus, because comparatively strong in extraneous survival ability, is not easy to be eliminated, so be easier to infect flock of sheep, easily in flock of sheep, causes epiphytotics generation.The goat fallen ill under normal circumstances can raise by body temperature, and varioliform exanthema appears in whole skin or local skin mucosa place, because be easier to infect, be easier to popular on a large scale when falling ill, mortality rate is higher.

At present, market mainly uses a large amount of antibiotic and antibody serum treatment goatpox, toxin is eliminated in vivo, thus reaches the object for the treatment of.

Such as: CN102266556 discloses a kind of based on P32 goatpox DNA vaccination and preparation method, and containing the eukaryon expression plasmid pVAX1-P32 of P 32 gene of goat capripoxvirus, plasmid concentration is 3mg ~ 10mg/mL.

CN101422607 discloses a kind of Peste des petis ruminants recombined goat pox virus movable carrier vaccine, and it comprises: (1) GPV attenuated vaccine, and it is as carrier; (2) the surperficial fusion protein F gene of the virus envelope of PPRV vaccine or hemagglutinin H gene, it is as object immunogene; (3) screening-gene, it comprises gpt, and reporter gene eGFP.These two kinds of vaccines called after GPV-PPRV-F (CGMCC No.2621) and GPV-PPRV-H (CGMCC No.2619) respectively.

CN102337264 discloses a kind of siRNA sequence of targeted inhibition capripox virus P32 gene, and sequence is GUGCUCCUAUUAUACUAAU.

But adopt the therapeutic modality drug residue of antibiotic and antibody serum large, treatment cost is higher, and cure rate is low.

Summary of the invention

The present invention overcomes the deficiencies in the prior art, provides a kind of herbal composite for the treatment of goatpox.Adopt herbal composite of the present invention to cure sick body, drug residue free, medicinal cost is low, can meet pollution-free, non-harmful health food demand.By early prevention and treatment, the state of an illness can be suppressed to spread, reduce epidemic disease risk.

Technical scheme of the present invention is:

Treat a herbal composite for goatpox, comprise the raw material of Chinese medicine of following weight ratio: Rhizoma Coptidis 40-60 part, Rhizoma Belamcandae 20-30 part, Radix Bupleuri 18-28 part, SHANZHIZI 16-25 part, Cortex Lycii 17-24 part, Radix Puerariae 45-56 part, Cortex Ailanthi 18-26 part, Semen phaseoli radiati 15-24 part.

Preferably, a kind of herbal composite for the treatment of goatpox, comprises the raw material of Chinese medicine of following weight ratio: Rhizoma Coptidis 45-52 part, Rhizoma Belamcandae 23-27 part, Radix Bupleuri 21-27 part, SHANZHIZI 18-21 part, Cortex Lycii 18-23 part, Radix Puerariae 47-53 part, Cortex Ailanthi 19-23 part, Semen phaseoli radiati 16-22 part.

Preferably, a kind of herbal composite for the treatment of goatpox, comprises the raw material of Chinese medicine of following weight ratio: Rhizoma Coptidis 50 parts, Rhizoma Belamcandae 25 parts, Radix Bupleuri 25 parts, SHANZHIZI 20 parts, Cortex Lycii 20 parts, Radix Puerariae 50 parts, Cortex Ailanthi 20 parts, 20 parts, Semen phaseoli radiati.

The pharmacological effect of crude drug of the present invention:

Rhizoma Coptidis, Cortex Lycii, Radix Puerariae improve microcirculation, and these three kinds of medicines share can remove disease sheep vivotoxin, improves skin microcirculation obstacle, accelerate wound healing.Concrete effect is as follows:

Rhizoma Coptidis: pathogenic fire purging, dampness, removing toxic substances, parasite killing.Row pyretic toxicity when controlling, typhoid fever, hotness is vexed, feeling of fullness vomiting, bacillary dysentery, the wet stomachache of heat, and lung knot is pressed, and tells, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, sore, eczema, the burning hot wound of soup.Materia Medica of Decoction: Rhizoma Coptidis hardship is dry, therefore enters the heart, fire is just also dry, so lets out the heart, in fact lets out spleen also, for son can make female real, actually lets out its son.

Cortex Lycii: Cortex Lycii, namely the root of Fructus Lycii also.Property very cold and cool, enter few cloudy kidney, and it is few positive three burnt to start with.Separate biography corpse and have the hot hectic fever due to YIN-deficiency of antiperspirant flesh, treat in the lossless rheumatism migratory arthralgia of table, go pathogenic heat in five, sharp large and small two just, the strong muscle of reinforcing YIN-essence, the cool bone of removing heat from blood.For the heat clearing away of lung heat clearing pathogenic fire reducing, quench one's thirst.

Radix Puerariae: sweet in the mouth, gas is put down, and body is gently up, and float and edge down, Yang Zhongyin is also, nontoxic.Enter stomach foot cloudy bright, cure the wound cold, deliver flesh heat.Enter spleen again, separate dry, promoting the production of body fluid to quench thirst.Alcoholic intoxication apoplexy, but pyrexial malaria alternate attacks of chills and fever, loose skin ulcer rash relieves the pain, and carries gas, and heat extraction steams.Heat clearing away, pathogenic fire reducing, toxin expelling, can improve microcirculation.

Rhizoma Belamcandae: pathogenic fire reducing, removing toxic substances, loose blood, expectorant." the southern regions of the Yunnan Province book on Chinese herbal medicine ": control laryngopharynx swelling and pain, pharynx wall acute throat trouble, newborn pretty young woman, mumps is red and swollen, and root of the tooth swells rotten, attacks the diseases such as all pyretic toxicity of loose carbuncle sore.For anti-inflammatory and suppression pathogenic microorganism, there is heat-clearing and toxic substances removing, vanishing sputum and dispelling knot, effect of loose blood detumescence.

SHANZHIZI, Radix Bupleuri two kinds of medicine combinations efficient solution can remove medicine to the infringement of sick sheep liver, pancreas, spleen.Concrete effect is as follows:

SHANZHIZI: pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.Calentura is vexed; Liver-fire conjunctival congestion; Headache; Damp and hot yellow infantile malnutrition; Stranguria; Dysentery hematuria; Aphtha of the mouth and tongue; " danxi's experiential therapy ": seed of Fructus Gardeniae, greatly energy pathogenic fire reducing, from urine venting.Its performance flexing declines, and people not known.Generally septum cordis pain, must divide for a long time new.If know cold of experiencing perfectly well, the cold thing of stutter and patient, when first, when medicine that is loose with temperature or temperature profit, if say disease slightly for a long time; Cheng Yu, Yu Ze steaming of a specified duration, heat must be lit a fire for a long time.For promoting pancreas and bile secretion, accelerate bilirubinic rapid excretion.

Radix Bupleuri: induce sweat and bring down a fever; Dispersing the stagnated live-QI to relieve the stagnation of QI, yang invigorating gas.Li Gao: Radix Bupleuri removing fire from the liver, must help it with Rhizoma Coptidis.Then root is used, steeping in wine for rising; For in and decline, by raw with slightly.Control again the skin infection hypochondriac lump on a left side.

Cortex Ailanthi: heat clearing and damp drying; Astringing intestine to stop diarrhea, hemostasis, leukorrhagia stopping." Chinese herbal medicine is commonly used in Sichuan ": can deliver, saturating measles.

Semen phaseoli radiati: cool in nature, sweet in the mouth, have heat clearing away, drive away summer heat, diuretic, removing toxic substances effect.Ancient medicine thinks that it can main erysipelas dysphoria with smothery sensation, rubella, treatment of smallpox poison, treats that carbuncle pox is rotten waits dermatopathy, and all by means of the power of its clearing away heat and promoting diuresis removing toxic substances, acute skin eczema person eats it, contributes to damp eliminating heat clearing away.Heat-clearing and toxic substances removing, diuresis of quenching the thirst, supplement moisture and inorganic salt in sick sheep body, maintains fluid electrolyte balance.

The all medicine compatibilities of Chinese medicine composition of the present invention, heat-clearing and toxic substances removing, reconciling superficies and interior, mediation physiological function, can drive away vivotoxin, and treatment goatpox has the effect for the treatment of both the principal and secondary aspects of a disease; Medicine source of the present invention is enriched, cheap.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described

Embodiment: the herbal composite for the treatment of goatpox, comprises following raw material of Chinese medicine: Rhizoma Coptidis 50 grams, Rhizoma Belamcandae 25 grams, Radix Bupleuri 25 grams, SHANZHIZI 20 grams, Cortex Lycii 20 grams, Radix Puerariae 50 grams, Cortex Ailanthi 20 grams, 20 grams, Semen phaseoli radiati.During treatment, get above-mentioned Chinese medicine, add water 8-10 kilogram, gets supernatant liquid filtering for subsequent use when boiling about 3-4 kilogram with slow fire.Adopt subcutaneous injection, sheep every per injection 10 milliliters of growing up, be bred as every only each 6 milliliters of sheep, lamb often only each 3 milliliters, one day twice, 3 days courses for the treatment of.

Model case

Case 1: field, goat raiser, livestock on hand goat 26.The JIUYUE 12 Days report state of an illness in 2012, sick sheep fever, loss of appetite, sheds tears, and erythema appears in skin of abdomen.Check: sick sheep body temperature raises, eyelid is red and swollen, conjunctival congestion, has serosity secretions, and pimple appears in tail base, the apparition of abdominal part red spot disease, and canescence vesicle appears in serious sick sheep, and clinical diagnosis is sheep pox.8 sick sheep and other Healthy Sheep in field are only isolated, gives traditional Chinese medicine composition for treating of the present invention.Sick sheep treats 3 courses for the treatment of, 1 course for the treatment of of other Healthy Sheep prophylactic treatment.8 sick sheep pass through treatment, fully recover after 28 days, cure rate 100%, and other healthy supporting only are prevented without cases of infection through medication.

Case 2: poplar, goat raiser, livestock on hand goat 50.The December 1 Days report state of an illness in 2012, poor appetite, lassitude, conjunctiva flushing. flow out epistasis or purulent rhinorrhea from nostril, breathing and pulse speed, and body temperature is elevated to 42 DEG C.Check: sick just sheep nasal mucosa is congested, rapid breathing, loss of appetite, lassitude, the sick sheep stream serosity had or mucus nasal mucus, eyelid swelled, conjunctival congestion, have serosity secretions, and nasal cavity has ulcer, without the skin generation kermesinus macule at hair or few hair position inside breast, pudendum, extremity etc., clinical diagnosis is sheep pox.27 sick sheep and other Healthy Sheep in field are only isolated, gives traditional Chinese medicine composition for treating of the present invention.Sick sheep treats 5 courses for the treatment of, 2 courses for the treatment of of other Healthy Sheep prophylactic treatment.27 sick sheep pass through treatment, fully recover after 45 days, cure rate 100%, and other healthy supporting only are prevented without cases of infection through medication.

Case 3: grandson, goat raiser, livestock on hand goat 72.April 14 in 2014 the Days report state of an illness, body temperature 41 ~ 42 DEG C, accelerated breathing, eye conjunctiva flushing, loss of appetite, spirit is depressed, and serosity mycopus sexual secretion is flowed out in nostril, and whole body has on the skin of hair-fields and occurs many spherical Bosses.Check: observe and touch as the outstanding tuberosity of Bufo siccus skin, quality is hard, and what have is linked to be the varioliform exanthema block differed in size, and spreads all over whole body; Varioliform exanthema is rounded, Semen Maydis, Semen Glycines size, uneven.Before shoulder, inguinal lymphadenopathy, little of Fructus Jujubae, large as egg.After a part dye epidemic disease sheep skin pox tuberosity comes off, occur red speckle, form blister ulceration, incrustation pox joint place can extrude pus, and clinical diagnosis is sheep pox.17 sick sheep and other Healthy Sheep in field are only isolated, give traditional Chinese medicine composition for treating of the present invention, sick sheep treats 3 courses for the treatment of, 2 courses for the treatment of of other Healthy Sheep prophylactic treatment.17 sick sheep pass through treatment, fully recover after 32 days, cure rate 100%, and other healthy supporting only are prevented without cases of infection through medication.

Claims (3)

1. treat a herbal composite for goatpox, it is characterized in that the raw material of Chinese medicine comprising following weight ratio: Rhizoma Coptidis 40-60 part, Rhizoma Belamcandae 20-30 part, Radix Bupleuri 18-28 part, SHANZHIZI 16-25 part, Cortex Lycii 17-24 part, Radix Puerariae 45-56 part, Cortex Ailanthi 18-26 part, Semen phaseoli radiati 15-24 part.

2. treat the herbal composite of goatpox according to claim 1, it is characterized in that the raw material of Chinese medicine comprising following weight ratio: Rhizoma Coptidis 45-52 part, Rhizoma Belamcandae 23-27 part, Radix Bupleuri 21-27 part, SHANZHIZI 18-21 part, Cortex Lycii 18-23 part, Radix Puerariae 47-53 part, Cortex Ailanthi 19-23 part, Semen phaseoli radiati 16-22 part.

3. treat the Chinese medicine composition of goatpox according to claim 1, it is characterized in that the raw material of Chinese medicine comprising following weight ratio: Rhizoma Coptidis 50 parts, Rhizoma Belamcandae 25 parts, Radix Bupleuri 25 parts, SHANZHIZI 20 parts, Cortex Lycii 20 parts, Radix Puerariae 50 parts, Cortex Ailanthi 20 parts, 20 parts, Semen phaseoli radiati.