CN104721280A - External drug composition for treating bone and joint ache and application of composition - Google Patents
External drug composition for treating bone and joint ache and application of composition Download PDFInfo
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- CN104721280A CN104721280A CN201510128249.5A CN201510128249A CN104721280A CN 104721280 A CN104721280 A CN 104721280A CN 201510128249 A CN201510128249 A CN 201510128249A CN 104721280 A CN104721280 A CN 104721280A
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Abstract
The invention discloses an external drug composition for treating a bone and joint ache and an application of the composition. The composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 90-120 parts of walnut leaves, 20-40 parts of crossostephium chinense, 15-25 parts of taxillus chinensis, 15-25 parts of roots of polygonum cuspidatum, 6-10 parts of seeds of firmiana plantanifolia and 21-30 parts of stephania tetrandra s.moore. The composition utilizes hyther and permeation of the drugs to allow local blood vessels at an infected part to be distended, accelerates blood circulation, increases tissue blood supply, accelerates removal of metabolites, improves local nutrition supply, relieves a spasm state of a local tissue, reduces inflammatory exudates, and accelerates absorption of pathological products, so that the purpose of alleviating pain is achieved.
Description
Technical field
The invention belongs to technical field of Chinese medicine, in particular to a kind of externally-applied medicinal composition and application thereof for the treatment of osteoarthrosis pain.
Background technology
Bone joint pain disease is more common in the medical patient of rural basic level hospital, belong to the category of Chinese medical ' arthralgia syndrome ', comprises a lot of sickly to plant as knee joint, ankle and toes metacarpal joint pain, prolapse of lumbar intervertebral disc, cervical spondylosis etc.The level such as armarium technology by basic hospital limit, and the expectant treatment that adopts as medicine and naturopathy more at present.Drug therapy, based on anti symptom treatment, uses various analgesic type drug, and naturopathy comprises traction, massage etc.But no matter be existing analgesic type drug or boring therapy, it is cures the symptoms, not the disease, and can rebound after drug withdrawal.
Summary of the invention
For the feature that rural area is high to the Chinese medicine degree of recognition, the present inventor selects Chinese medicine fumigation and washing therapy, provides a kind of externally-applied medicinal composition and application thereof for the treatment of osteoarthrosis pain, achieves good effect.
The object of the present invention is achieved like this:
Treat an externally-applied medicinal composition for osteoarthrosis pain, said composition is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: leaf of Semen Juglandis 90-120 part, Chinese mugwort 20-40 part in thousand, Herba Taxilli 15-25 part, polygoni cuspidati,radix 15-25 part, Semen Firmianae 6-10 part, Radix Stephaniae Tetrandrae 21-30 part.
Preferably, the externally-applied medicinal composition for the treatment of osteoarthrosis pain as above, it is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: leaf of Semen Juglandis 97-105 part, Chinese mugwort 28-32 part in thousand, Herba Taxilli 18-22 part, polygoni cuspidati,radix 18-22 part, Semen Firmianae 7-9 part, Radix Stephaniae Tetrandrae 24-26 part.
In a prepreerence embodiment of the present invention, the externally-applied medicinal composition for the treatment of osteoarthrosis pain as above, it is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: leaf of Semen Juglandis 100 parts, Chinese mugwort 30 parts in thousand, Herba Taxilli 20 parts, polygoni cuspidati,radix 20 parts, Semen Firmianae 8 parts, Radix Stephaniae Tetrandrae 25 parts.
Further preferably, the externally-applied medicinal composition for the treatment of osteoarthrosis pain as above, it is smouldering washing solution.
Test proves, the pharmaceutical composition that the present invention relates to is passed through fumigation-washing therapy, can make the local vascular dilation in affected part, blood circulation is accelerated, and increases and organizes blood supply, accelerate the removing of metabolite, improve the nutrition supply of local, remove the spasticity of local organization, reduce inflammatory thing and ooze out, accelerate the absorption of pathological product, and reach lenitive object.Therefore, present invention also offers a kind of medical usage, that is: the application of above-mentioned Chinese medicine composition in the medicine or care product of preparation treatment osteoarthrosis pain disease.Further, described osteoarthrosis pain disease knee joint, ankle and toes metacarpal joint pain.
It should be noted that, the traditional Chinese medicinal material raw materials that pharmaceutical composition of the present invention adopts has following source: leaf of Semen Juglandis selects the dried leaves of juglandaceae plant Semen Juglandis Juglans regia L..The dry root of Ai Xuanyong Compositae Hibisci Mutabilis Dendranthema in thousand Chinese mugwort Crossostephium chinense (L.) Makino in thousand.Herba Taxilli selects the dry stem and branch with leaf of Loranthaceae plant Herba Taxilli Taxilluschinensis (DC.) Danser.Polygoni cuspidati,radix selects the dry root of polygonaceae plant Rhizoma Polygoni Cuspidati Polygonumcuspidatum Sieb.et Zucc..Semen Firmianae selects the dry seed of Sterculiaceae plant Firmiana platanifolia (Linn. f.) Marsili Firmiana plantanifolia (L.f.) Marsili [F.simplex (L.) W.F.Wight].The dry root of menispermaceous plants Radix stephaniae tetrandrae Stephania tetrandra S.Moore selected by Radix Stephaniae Tetrandrae.
Externally-applied medicinal composition of the present invention utilizes the damp and hot of medicine and osmosis, make the local vascular dilation in affected part, blood circulation is accelerated, increase and organize blood supply, accelerate the removing of metabolite, improve the nutrition supply of local, remove the spasticity of local organization, reduce inflammatory thing to ooze out, accelerate the absorption of pathological product, and reach lenitive object.
Detailed description of the invention
Be below specific embodiments of the invention, technical scheme of the present invention is done to describing further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Take traditional Chinese medicinal material raw materials leaf of Semen Juglandis 1.0kg, Chinese mugwort 0.30kg, Herba Taxilli 0.20kg, polygoni cuspidati,radix 0.20kg, Semen Firmianae 0.08kg and Radix Stephaniae Tetrandrae 0.25kg in thousand, merge, pulverize, add the soak by water 1.5h of medical material weight 10 times amount, filter, collect filtrate; The soak by water 1h of medical material weight 8 times amount is added again in medicinal residues, filter, collect filtrate, twice filtrate is merged, be concentrated into liquor capacity (ml): medical material weight (g)=2: the concentrated solution of 1, and 0.1% add antiseptic ethyl hydroxybenzoate, by every bag of 100 milliliters of subpackages by weight percentage.
Embodiment 2
Take traditional Chinese medicinal material raw materials leaf of Semen Juglandis 0.90kg, Chinese mugwort 0.20kg, Herba Taxilli 0.25kg, polygoni cuspidati,radix 0.25kg, Semen Firmianae 0.10kg and Radix Stephaniae Tetrandrae 0.25kg in thousand, merge, pulverize, add the soak by water 1.5h of medical material weight 10 times amount, filter, collect filtrate; In medicinal residues, add the soak by water 1h of medical material weight 8 times amount again, filter, collect filtrate, twice filtrate is merged, be concentrated into liquor capacity: medical material weight=2: the concentrated solution of 1, and 0.1% add antiseptic ethyl hydroxybenzoate, by every bag of 100 milliliters of subpackages by weight percentage.
Embodiment 3
Take traditional Chinese medicinal material raw materials leaf of Semen Juglandis 1.0kg, Chinese mugwort 0.40kg, Herba Taxilli 0.15kg, polygoni cuspidati,radix 0.15kg, Semen Firmianae 0.08kg and Radix Stephaniae Tetrandrae 0.30kg in thousand, merge, pulverize, add the soak by water 1h of medical material weight 10 times amount, filter, collect filtrate; In medicinal residues, add the soak by water 0.8h of medical material weight 10 times amount again, filter, collect filtrate, twice filtrate is merged, be concentrated into liquor capacity: medical material weight=2: the concentrated solution of 1, and 0.1% add antiseptic ethyl hydroxybenzoate, by every bag of 100 milliliters of subpackages by weight percentage.
Embodiment 4
Take traditional Chinese medicinal material raw materials leaf of Semen Juglandis 1.05kg, Chinese mugwort 0.32kg, Herba Taxilli 0.25kg, polygoni cuspidati,radix 0.20kg, Semen Firmianae 0.08kg and Radix Stephaniae Tetrandrae 0.21kg in thousand, merge, pulverize, add the soak by water 1h of medical material weight 12 times amount, filter, collect filtrate; In medicinal residues, add the soak by water 1h of medical material weight 10 times amount again, filter, collect filtrate, twice filtrate is merged, be concentrated into liquor capacity: medical material weight=2: the concentrated solution of 1, and 0.1% add antiseptic ethyl hydroxybenzoate, by every bag of 100 milliliters of subpackages by weight percentage.
Comparative example
Take traditional Chinese medicinal material raw materials leaf of Semen Juglandis 2.0kg to pulverize, add the soak by water 1.5h of medical material weight 10 times amount, filter, collect filtrate; The soak by water 1h of medical material weight 8 times amount is added again in medicinal residues, filter, collect filtrate, twice filtrate is merged, be concentrated into liquor capacity (ml): medical material weight (g)=2: the concentrated solution of 1, and 0.1% add antiseptic ethyl hydroxybenzoate, by every bag of 100 milliliters of subpackages by weight percentage.
The clinical practice example of embodiment 5 Chinese traditional herbal medicine treatment osteoarthrosis pain
Osteoarthrosis pain patient 48 example, still can not alleviate with knee joint, ankle and toes metacarpal joint pain, chronic phase and eliminate as main clinical manifestation, pain is based on dull pain, all with arthralgia (without red red) in various degree, handicapped, ankylosis, very then joint deformity, downstairs upper and activity is subject to certain restriction.Wherein male 21 example, women 27 example; Age 39-72 year, average 57.3 ± 8.1 years old; The course of disease is the longest 15 years, the shortest 3 months, average 3.6 ± 0.8 years.According to random packet principle, 48 routine osteoarthrosis pain patients are divided at random test A group and each 24 examples of test B group, two groups of patients compare there was no significant difference in sex, age, the course of disease etc., have comparability.
The compound medicines liquid fumigation in treating that test A group adopts above-described embodiment 1 to prepare, the leaf of Semen Juglandis decocting liquid liquid fumigation in treating that test B group is prepared by above-mentioned comparative example.Fumigation in treating method is: taking liquid one bag is poured in keg, adds boiled water 1.5L, adds herbal fumigation instrument, and patient lies on fumigation instrument bed, and stifling tender joint place is about 20-30 minute, dips medicinal liquid apply affected part 20-30 minute when fluid temperature is suitable for towel; Every Japan-China each 1 time sooner or later, continuous fumigation in treating 15d.
It is as follows that " evaluation of Chinese medical disease Standardization of diagnosis and curative effect " of promulgating with reference to national traditional chinese medical science administration drafts curative effect judging standard: fully recover for pain disappears, knee joint function activity recovers normal.Effectively obviously alleviate for pain, functional activity is slightly influenced.Heavy time light when being effectively pain, functional activity slightly improves.Invalid is that pain and functional activity are all without improvement.
Result of the test is in table 1.Can be found out by the statistical result of table 1, test A group recovery from illness 11 example, effective 8 examples, effective 5 examples, total effective rate 100%; Test B group is fullyed recover from an illness 0 example, effective 6 examples, effective 9 examples, no effect 9, total effective rate 62.5%; The treatment total effective rate of test A group is apparently higher than test B group.
Table 1 liang group curative effect statistical result (n=24)
Claims (6)
1. treat an externally-applied medicinal composition for osteoarthrosis pain, it is characterized in that: described compositions is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: leaf of Semen Juglandis 90-120 part, Chinese mugwort 20-40 part in thousand, Herba Taxilli 15-25 part, polygoni cuspidati,radix 15-25 part, Semen Firmianae 6-10 part, Radix Stephaniae Tetrandrae 21-30 part.
2. the externally-applied medicinal composition for the treatment of osteoarthrosis pain according to claim 1, it is characterized in that: described compositions is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: leaf of Semen Juglandis 97-105 part, Chinese mugwort 28-32 part in thousand, Herba Taxilli 18-22 part, polygoni cuspidati,radix 18-22 part, Semen Firmianae 7-9 part, Radix Stephaniae Tetrandrae 24-26 part.
3. the externally-applied medicinal composition for the treatment of osteoarthrosis pain according to claim 2, is characterized in that: described compositions is prepared from by the traditional Chinese medicinal material raw materials of following weight portion: leaf of Semen Juglandis 100 parts, Chinese mugwort 30 parts in thousand, Herba Taxilli 20 parts, polygoni cuspidati,radix 20 parts, Semen Firmianae 8 parts, Radix Stephaniae Tetrandrae 25 parts.
4. the externally-applied medicinal composition of the treatment osteoarthrosis pain according to claim 1 or 2 or 3, is characterized in that: described externally-applied medicinal composition is smouldering washing solution.
5. the application of compositions described in claim 1 or 2 or 3 in the external used medicine or care product for the treatment of osteoarthrosis pain disease.
6. application according to claim 5, is characterized in that, described osteoarthrosis pain disease knee joint, ankle and toes metacarpal joint pain.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510128249.5A CN104721280A (en) | 2015-03-24 | 2015-03-24 | External drug composition for treating bone and joint ache and application of composition |
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| CN201510128249.5A CN104721280A (en) | 2015-03-24 | 2015-03-24 | External drug composition for treating bone and joint ache and application of composition |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456348A (en) * | 2015-12-28 | 2016-04-06 | 青岛昌安达药业有限公司 | Traditional Chinese medicine composition for treating arthralgia |
| CN108653651A (en) * | 2018-06-14 | 2018-10-16 | 山东融基健康管理股份有限公司 | A kind of pennywort dredging collateral dampness elimination drug moxa stick and its processing technology |
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| CN1304760A (en) * | 2000-12-14 | 2001-07-25 | 惠留义 | Plaster for treating ostalgia and its preparing process |
| CN1398618A (en) * | 2002-09-09 | 2003-02-26 | 李永胜 | Chinese medicine capsule for treating rbeumatism and protrusion of lumber interverterbral disc |
| CN1966003A (en) * | 2006-11-22 | 2007-05-23 | 姜方森 | Externally applied medicament for treating rheumatism |
| CN103239654A (en) * | 2013-05-10 | 2013-08-14 | 钟映莉 | Medicine for treating acute gouty arthritis |
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2015
- 2015-03-24 CN CN201510128249.5A patent/CN104721280A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1304760A (en) * | 2000-12-14 | 2001-07-25 | 惠留义 | Plaster for treating ostalgia and its preparing process |
| CN1398618A (en) * | 2002-09-09 | 2003-02-26 | 李永胜 | Chinese medicine capsule for treating rbeumatism and protrusion of lumber interverterbral disc |
| CN1966003A (en) * | 2006-11-22 | 2007-05-23 | 姜方森 | Externally applied medicament for treating rheumatism |
| CN103239654A (en) * | 2013-05-10 | 2013-08-14 | 钟映莉 | Medicine for treating acute gouty arthritis |
Non-Patent Citations (1)
| Title |
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| 成都中医学院《实用中医学》编写组: "腰腿痛", 《实用中医学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456348A (en) * | 2015-12-28 | 2016-04-06 | 青岛昌安达药业有限公司 | Traditional Chinese medicine composition for treating arthralgia |
| CN108653651A (en) * | 2018-06-14 | 2018-10-16 | 山东融基健康管理股份有限公司 | A kind of pennywort dredging collateral dampness elimination drug moxa stick and its processing technology |
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Application publication date: 20150624 |