CN104689272A - Traditional Chinese medicine for treating hyperlipidemia caused by deficiency of liver and kidneys - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating hyperlipidemia caused by deficiency of the liver and kidneys. The traditional Chinese medicine is prepared from alectoria asiatica du rietz, malus kansuensis, gelafinae, radix rehmanniae preparata, glossy privet fruit, endothelium corneum gigeriae galli, cinnamon, equisetum hiemale, baked ginger and lily. The traditional Chinese medicine can be clinically applied to treatment of hyperlipidemia caused by deficiency of the liver and kidneys.

Description

A kind of Chinese medicine for the treatment of deficiency of the liver and kidney hyperlipemia

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of deficiency of the liver and kidney hyperlipemia.

Background technology

Hyperlipidemia is one of common multiple diseases.Suffer from this patient, it shows as gallbladder in blood or content of triglyceride and occurs extremely increasing phenomenon, and high density lipoprotein occurs reducing phenomenon.Hyperlipemia belongs to the categories such as Chinese medicine phlegm-damp, turbid resistance, blood stasis, and Chinese medicine thinks that blood fat is the genus of cream fat, and its metabolism depends on the gasification of internal organs.This type of patient's many addiction to greasy and sweet foods savoury, in addition less physical activities at ordinary times, and cause dysfunction of the spleen in transportation and can not transport wet cloth Tianjin.The liver failing to maintain the normal flow of QI, disorder of QI movement, therefore the micro-and accumulatively wet raise phlegm of the angry hemospermia of being difficult of product of water paddy delicious food, Tianjin is cream from turbidity, solidifying and be fat, and be mixed in blood, QI-blood circulation is smooth, and expectorant stasis blocking is stagnant, and passages through which vital energy circulates loses supports, for a long time then caused by liver and kidney deficiency, and disease benefit is contained.Deficiency of the liver and kidney hyperlipemia clinical symptoms mainly contains: have a dizzy spell, lustreless complexion, aversion to cold and cold limbs, fatigue and weakness, oppression sensation over the epigastrium and anorexia, soreness of the waist and knees, or had palpitation night sweat, dysphoria and insomnia, light red tongue, white and thin fur or few tongue, thready and moderate pulse or heavy sliding, the Chinese medicine that the present invention prepares has good effect to deficiency of the liver and kidney hyperlipemia.

Summary of the invention

The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the treatment deficiency of the liver and kidney hyperlipemia of human non-toxic's side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Alectoria asiatica Du Rietz, Malus kansuensis (Batal.) Schned, Eucheuma gelatinosum, Radix Rehmanniae Preparata, Fructus Ligustri Lucidi, Endothelium Corneum Gigeriae Galli, Cortex Cinnamomi, Herba Equiseti Hiemalis, Rhizoma Zingiberis Preparatum, Bulbus Lilii, according to certain compatibility requirement, through being processed into.

Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Alectoria asiatica Du Rietz 35-45 part, Malus kansuensis (Batal.) Schned 20-30 part, Eucheuma gelatinosum 20-30 part, Radix Rehmanniae Preparata 20-30 part, Fructus Ligustri Lucidi 15-25 part, Endothelium Corneum Gigeriae Galli 15-25 part, Cortex Cinnamomi 15-25 part, Herba Equiseti Hiemalis 10-15 part, Rhizoma Zingiberis Preparatum 10-15 part, Bulbus Lilii 10-15 part.

Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Alectoria asiatica Du Rietz 40 parts, Malus kansuensis (Batal.) Schned 25 parts, Eucheuma gelatinosum 25 parts, 25 parts, Radix Rehmanniae Preparata, Fructus Ligustri Lucidi 20 parts, Endothelium Corneum Gigeriae Galli 20 parts, Cortex Cinnamomi 20 parts, Herba Equiseti Hiemalis 12 parts, Rhizoma Zingiberis Preparatum 12 parts, Bulbus Lilii 12 parts.

The pharmacological action of Chinese medicine of the present invention is as follows:

Alectoria asiatica Du Rietz: light, flat.Return liver, kidney, urinary bladder channel.Nourishing the kidney and liver, arresting seminal emission hidroschesis, inducing diuresis to remove edema, removing dampness sore.For kidney deficiency and bodily weakness, arresting seminal emission hidroschesis, cardiopalmus, seminal emission, night sweat, stranguria, edema, impetigo etc.

Malus kansuensis (Batal.) Schned: sour, flat.Return spleen, stomach warp.Stomach invigorating removing food stagnancy.Cure mainly food stagnation.

Eucheuma gelatinosum: sweet, salty, cold.Return lung, liver, large intestine channel.Removing heat from the lung and dissipating phlegm, hard masses softening and resolving, removing toxic substances.Clinical in phlegm-heat cough, gall subcutaneous nodule, swelling and pain of hemorrhoid or hematochezia, the diseases such as enteritis.

Radix Rehmanniae Preparata: sweet, tepor.Return liver, kidney channel.Enrich blood YIN nourishing, beneficial essence fills out marrow.For blood deficiency and yellow complexion, dizzy, palpitation and insomnia; Deficiency of kidney yin and the hectic fever hectic fever due to YIN-deficiency caused, night sweat, seminal emission; The soreness of the waist and knees of Liver and kidney blood and essence asthenia, vertigo and tinnitus, early whitening of beard and hair etc.

Fructus Ligustri Lucidi: sweet, bitter, cool.Return liver, kidney channel.Liver and kidney tonifying, clearind deficient heat, improving eyesight.For Light-headedness, soreness of the waist and knees, the cards such as tinnitus.

Endothelium Corneum Gigeriae Galli: sweet, flat.Return spleen, stomach, kidney, urinary bladder channel.Strengthening the spleen to promote digestion, arresting seminal emission.Cure mainly dyspepsia, eating accumulation, vomiting regurgitation, dysentery of having loose bowels, infantile malnutrition, seminal emission, the enuresis, frequent micturition, urinary system calculus and cholelithiasis ， mass in the abdomen amenorrhea, sore throat tonsillitis, ulcerative gingivitis aphtha etc.

Cortex Cinnamomi: pungent, sweet, hot.Return spleen, kidney, the heart, Liver Channel.Mend fire supporing yang, dispersing cold for relieving pain, warming the meridian and promoting blood circulation.For the sexual impotence cold womb that kidney yang is weak, dyspnea due to deficiency cardiopalmus, trusted subordinate's cold type of pain, colic of cold type is had a pain, arthralgia due to cold lumbago, the thoracic obstruction, and amenorrhea, stimulates the menstrual flow.

Herba Equiseti Hiemalis: sweetness and bitterness, flat.Return lung, liver, gallbladder meridian.Wind and heat dispersing, cooling blood for hemostasis, improving acuity of vision and removing nebula.For wind heat conjunctival congestion, the raw nebula of order, discharging fresh blood stool, hemorrhoidal bleeding, dysentery, married woman's metrorrhagia, proctoptosis etc.

Rhizoma Zingiberis Preparatum: bitter, pungent, warm.Return spleen, stomach, Liver Channel.Warming middle-JIAO to stop diarrhea, warming middle-JIAO stops blooding.Cure mainly deficient cold type epigastric pain, vomiting, dysentery, spit blood, have blood in stool, metrorrhagia etc.

Bulbus Lilii: sweet, micro-hardship, to be slightly cold.GUIXIN, lung meridian.Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Clinical in deficiency of YIN chronic cough, sputum mixed with blood, in the calentura later stage, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, carbuncle, the diseases such as eczema.

Hyperlipemia belongs to the category of " obesity ", " apoplexy ", " dizzy " of Chinese medicine, " blood stasis ", " phlegm-damp ", and is in easy circumstances, diet delicious food savoury, the rare pass of quantity of motion.Alectoria asiatica Du Rietz nourishing the kidney and liver of the present invention is monarch drug, Malus kansuensis (Batal.) Schned stomach invigorating removing food stagnancy, Eucheuma gelatinosum powder detoxifcation, Radix Rehmanniae Preparata enrich blood YIN nourishing, beneficial essence fills out marrow, is ministerial drug, Fructus Ligustri Lucidi liver and kidney tonifying, Endothelium Corneum Gigeriae Galli strengthening the spleen to promote digestion, Cortex Cinnamomi mends supporing yang, the promoting the flow of QI-blood by warming the meridian of fire, Herba Equiseti Hiemalis's dispelling wind detoxifies, and Rhizoma Zingiberis Preparatum warming middle-JIAO, is calmed the nerves at Bulbus Lilii yin nourishing, play nourishing the kidney and liver altogether, spleen invigorating removing food stagnancy, YIN nourishing of enriching blood, effect that removing toxic substances is calmed the nerves, reaches the object for the treatment of deficiency of the liver and kidney hyperlipemia.

Chinese medicine of the present invention is used in 2008 to 2013 the routine patients of clinical observation deficiency of the liver and kidney hyperlipemia disease 112, and clinical report is as follows:

1, physical data

In 112 routine patients, women 69 example, male 43 example, at minimum 52 years old of age, maximum 72 years old, the course of disease was many at 5 months to 3 years, 56 years old mean age.

2, diagnostic criteria

With reference to " new Chinese medicine guideline of clinical investigations ":

(1) Western medicine diagnose standard: in normal diet situation, 2 weeks interior survey for 2 times serum total cholesterol (TC) all >=6.0mmol/L (230mg/dL), or triglyceride (TG) >=1.54mmol/L (140mg/dL), or HDL-C (HDL-C) man≤1.04mmol/L (40mg/dL), female≤1.17mmol/L (45mg/dL) person.

(2) Standards of Chinese Medical Syndrome Differentiation: have a dizzy spell, lustreless complexion, aversion to cold and cold limbs, fatigue and weakness, oppression sensation over the epigastrium and anorexia, soreness of the waist and knees, or had palpitation night sweat, dysphoria and insomnia, light red tongue, white and thin fur or few tongue, thready and moderate pulse or heavy sliding.

3, Therapeutic Method

3.1 prescriptions: Alectoria asiatica Du Rietz 40g, Malus kansuensis (Batal.) Schned 25g, Eucheuma gelatinosum 25g, Radix Rehmanniae Preparata 25g, Fructus Ligustri Lucidi 20g, Endothelium Corneum Gigeriae Galli 20g, Cortex Cinnamomi 20g, Herba Equiseti Hiemalis 12g, Rhizoma Zingiberis Preparatum 12g, Bulbus Lilii 12g.

3.2 preparation methoies: said medicine routinely technique makes decoction.

3.3 instructions of taking: each 1 dose, every day 2 times 30 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 with reference to " new Chinese medicine guideline of clinical investigations ":

Clinical cure: clinical symptoms, sign disappear, the every inspection of laboratory recovers normal.

Effective: clinical symptoms, sign disappear substantially, lipids detection reaches following any one person: TC decline >=20%, TG decline >=40%, HDL-C rising >=0.26mmol/L (10mg/dL), TC-HDL-C/HDL-C decline >=20%.

Effective: clinical symptoms, sign all take a favorable turn, lipids detection reaches following any one person: TC declines >=10% but < 20%, TG declines >=20% but < 40%, HDL-C rising >=0.104mmol/L (4mg/dL) but < 0.26mmol/L (10mg/dL), TC-HDL-C/HDL-C decline >=10% but < 20%.

Invalid: symptom, sign and the lipids detection person of being not improved after treatment.

4.2 results: in 112 routine patients, cure 57 examples (50.9%), effective 30 examples (26.8%), effective 17 examples (15.2%), and do not heal 8 examples (7.1%), and total effective rate is 92.9%.

5, model case

5.1 weeks certain, man, 66 years old, uncomfortable in chest, headache, soreness of the waist and knees, extremity fear of cold, vexed hypochondriac pain, light red tongue, thready pulse.On inspection, serum total cholesterol (TC) 7.4mmol/L, triglyceride (TG) 2.31mmol/L.Take Chinese medicine of the present invention to treat, after treating 2 courses for the treatment of, all diseases disappear all, serum total cholesterol (TC) 5.3mmol/L, triglyceride (TG) 1.17mmol/L, recovery from illness.

5.2 beams, female, 59 years old, dizzy, uncomfortable in chest, breathe hard, vexed, light red tongue, few tongue, rolling pulse.On inspection, serum total cholesterol (TC) 7.06mmol/L, triglyceride (TG) 3.11mmol/L.Take the Chinese medicine that the present invention treats deficiency of the liver and kidney hyperlipemia to treat, after treating 2 courses for the treatment of, all diseases disappear all, serum total cholesterol (TC) 5.31mmol/L, triglyceride (TG) 1.23 mmol/L, recovery from illness.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.

Embodiment 1, a kind of Chinese medicine for the treatment of deficiency of the liver and kidney hyperlipemia, it is made up of following raw material medicaments: Alectoria asiatica Du Rietz 35g, Malus kansuensis (Batal.) Schned 20g, Eucheuma gelatinosum 20g, Radix Rehmanniae Preparata 20g, Fructus Ligustri Lucidi 15g, Endothelium Corneum Gigeriae Galli 15g, Cortex Cinnamomi 15g, Herba Equiseti Hiemalis 10g, Rhizoma Zingiberis Preparatum 10g, Bulbus Lilii 10g.

Embodiment 2, a kind of Chinese medicine for the treatment of deficiency of the liver and kidney hyperlipemia, it is made up of following raw material medicaments: Alectoria asiatica Du Rietz 40g, Malus kansuensis (Batal.) Schned 25g, Eucheuma gelatinosum 25g, Radix Rehmanniae Preparata 25g, Fructus Ligustri Lucidi 20g, Endothelium Corneum Gigeriae Galli 20g, Cortex Cinnamomi 20g, Herba Equiseti Hiemalis 12g, Rhizoma Zingiberis Preparatum 12g, Bulbus Lilii 12g.

Embodiment 3, a kind of Chinese medicine for the treatment of deficiency of the liver and kidney hyperlipemia, it is made up of following raw material medicaments: Alectoria asiatica Du Rietz 45g, Malus kansuensis (Batal.) Schned 30g, Eucheuma gelatinosum 30g, Radix Rehmanniae Preparata 30g, Fructus Ligustri Lucidi 25g, Endothelium Corneum Gigeriae Galli 25g, Cortex Cinnamomi 25g, Herba Equiseti Hiemalis 15g, Rhizoma Zingiberis Preparatum 15g, Bulbus Lilii 15g.

Claims (2)

1. treat a Chinese medicine for deficiency of the liver and kidney hyperlipemia, it is characterized in that being made up of following crude drug:

Alectoria asiatica Du Rietz 35-45 part, Malus kansuensis (Batal.) Schned 20-30 part, Eucheuma gelatinosum 20-30 part, Radix Rehmanniae Preparata 20-30 part,

Fructus Ligustri Lucidi 15-25 part, Endothelium Corneum Gigeriae Galli 15-25 part, Cortex Cinnamomi 15-25 part, Herba Equiseti Hiemalis 10-15 part,

Rhizoma Zingiberis Preparatum 10-15 part, Bulbus Lilii 10-15 part.

2. Chinese medicine according to claim 1, is characterized in that being made up of following crude drug:

Alectoria asiatica Du Rietz 40 parts, Malus kansuensis (Batal.) Schned 25 parts, Eucheuma gelatinosum 25 parts, 25 parts, Radix Rehmanniae Preparata,

Fructus Ligustri Lucidi 20 parts, Endothelium Corneum Gigeriae Galli 20 parts, Cortex Cinnamomi 20 parts, Herba Equiseti Hiemalis 12 parts,

Rhizoma Zingiberis Preparatum 12 parts, Bulbus Lilii 12 parts.