CN104689196A - Traditional Chinese medicine for treating hyperlipemia caused by phlegm obstruction - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating hyperlipemia caused by phlegm obstruction. The traditional Chinese medicine is prepared from the following raw materials: milk wood, wax gourd stem, gentiana hexaphylla maxim, platycodon grandiflorum, incarvillea compacta, costus tonkinensis, rhizoma atractylodis macrocephalae, pericarpium citri reticulatae, rheum officinale and beauveria bassiana vuill. The traditional Chinese medicine can be applied to treatment of hyperlipemia caused by phlegm obstruction in clinical.

Description

A kind of Chinese medicine for the treatment of essential resistance of turbid phlegm type hyperlipemia

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of essential resistance of turbid phlegm type hyperlipemia.

Background technology

Hyperlipemia is common clinical, frequently-occurring disease.Doctor trained in Western medicine is thought, blood fat is the general name of contained lipid in human plasma.Comprising cholesterol, triglyceride, cholesterol ester, beta Lipoprotein, phospholipid, not esterified fat acid etc.When serum cholesterol exceedes normal value 230mg/100ml, triglyceride, more than 140mg/100ml, when beta Lipoprotein is more than more than 390mg/100ml, can be referred to as hyperlipemia.Hyperlipemia can cause the generation of cardiovascular and cerebrovascular disease, is the high risk factor of the diseases such as atherosclerosis, coronary heart disease, myocardial infarction, cerebral thrombosis, cerebral hemorrhage, is the underlying etiology that the Major Vessels atherosclerosiss such as the heart, brain, kidney occur and develop.The Chinese medicine that the present invention prepares has good effect to essential resistance of turbid phlegm type hyperlipemia.

Summary of the invention

The object of the present invention is to provide a kind of therapeutic effect good, effective percentage is high, to the Chinese medicine of the treatment essential resistance of turbid phlegm type hyperlipemia of human non-toxic's side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Fici hispidae, Caulis Benincasae, Radix Gentianae, Radix Platycodonis, Radix Incarvilleae compactae, photooxidative stress, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, Radix Et Rhizoma Rhei, Bombyx Batryticatus, according to certain compatibility requirement, through being processed into.

Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Fici hispidae 30-40 part, Caulis Benincasae 20-30 part, Radix Gentianae 20-30 part, Radix Platycodonis 20-30 part, Radix Incarvilleae compactae 15-25 part, photooxidative stress 15-25 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Pericarpium Citri Reticulatae 15-25 part, Radix Et Rhizoma Rhei 10-15 part, Bombyx Batryticatus 2-5 part.

Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Fici hispidae 35 parts, Caulis Benincasae 25 parts, Radix Gentianae 25 parts, Radix Platycodonis 25 parts, Radix Incarvilleae compactae 20 parts, photooxidative stress 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Pericarpium Citri Reticulatae 20 parts, Radix Et Rhizoma Rhei 12 parts, Bombyx Batryticatus 3 parts.

The pharmacological action of Chinese medicine of the present invention is as follows:

Fici hispidae: sweet, micro-hardship, cool.Dispelling wind is antipyretic, and removing food stagnancy reduces phlegm, and spleen invigorating dehumidifies, circulation of qi promoting dissipating blood stasis.Clinical in cold, fever, conjunctivitis, bronchitis, dyspepsia, dysentery, lukorrhagia due to hypofunction of the spleen, agalactia, treating swelling and pain by traumatic injury, the diseases such as rheumatic arthralgia.

Caulis Benincasae: bitter, cold.Return lung, Liver Channel.Removing heat from the lung and dissipating phlegm, dredge the meridian passage.For cough due to lung-heat, articular instability, proctoptosis, the diseases such as scabies.

Radix Gentianae: bitter, warm.Removing toxic substances, dampness.Clinical in anthrax, rheumatic arthralgia.

Radix Platycodonis: bitter, pungent, flat.Attach to the lung and stomach meridians.Lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus.For cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, the full hypochondriac pain of born of the same parents, dysentery stomachache etc.

Radix Incarvilleae compactae: bitter, sweet, flat.Return liver, spleen, lung, stomach warp.Heat clearing away, removing toxic substances, dampness, helps digestion.Cure mainly heating, jaundice, otitis media, dyspepsia, stomachache, the diseases such as gastral cavity abdomen constipation.

Photooxidative stress: acrid in the mouth, cold in nature.Inducing diuresis to remove edema, wind-damp dispelling, removing toxic substances, clinical in cirrhotic ascites, oedema due to nephritis, urinary tract infection, scrotum swells and ache, rheumatic arthralgia, innominate toxic swelling, urticaria etc.

The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive.For deficiency of spleen-QI and stomach-QI, transporting is unable, anorexia and loose stool, distension and fullness in the abdomen, insufficiency of the spleen water retention, and is phlegm retention, edema, dysuria, frequent fetal movement etc.

Pericarpium Citri Reticulatae: acrid, bitter, warm, returns spleen, stomach, lung meridian.Regulate the flow of vital energy in adjusting, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.Full vexed for chest and diaphragm, abdominal distention, anorexia, vomiting etc.

Radix Et Rhizoma Rhei: bitter, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, effect of removing toxic substances.For excess-heat constipation, the accumulation of heat feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria, conjunctival congestion etc.

Bombyx Batryticatus: salty, pungent, flat.Return liver, lung, stomach warp.Heat clearing away is relieving convulsion, preventing phlegm from forming and stopping coughing, dispersing swelling and dissipating binds.Clinical in hyperpyrexia and infantile convulsion, spasm is twitched, acute laryngitis, parotitis, acute and chronic bronchitis, urticaria, hyperlipidemia.

Hyperlipemia belongs to the category of " obesity ", " apoplexy ", " dizzy " of Chinese medicine, " blood stasis ", " phlegm-damp ", and is in easy circumstances, diet delicious food savoury, the rare pass of quantity of motion.Fici hispidae removing food stagnancy of the present invention reduces phlegm, spleen invigorating dehumidifying, is monarch drug, Caulis Benincasae reduces phlegm, dredging collateral, Radix Gentianae removing toxic substances, dampness, be ministerial drug, Radix Platycodonis lung qi dispersing, eliminate the phlegm, Radix Incarvilleae compactae heat clearing away, removing toxic substances, dampness, photooxidative stress diuretic, damp eliminating, removing toxic substances, Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening, dampness diuretic, Pericarpium Citri Reticulatae drying dampness to eliminate phlegm, Radix Et Rhizoma Rhei clearing away damp-heat, removing toxic substances, Bombyx Batryticatus reduces phlegm, calm, eliminating stagnation, plays the spleen strengthening and damp drying altogether and reduces phlegm, promoting blood circulation to remove obstruction in the collateral, effect of heat-clearing and toxic substances removing, reaches the object for the treatment of essential resistance of turbid phlegm type hyperlipemia.

Chinese medicine of the present invention is used in 2009 to 2013 the routine patients of clinical observation essential resistance of turbid phlegm type hyperlipemia disease 64, and clinical report is as follows:

1, physical data

In 64 routine patients, women 31 example, male 33 example, at minimum 29 years old of age, maximum 76 years old, the course of disease was many at 8 months to 10 years, 47.5 years old mean age.

2, diagnostic criteria

With reference to " new Chinese medicine guideline of clinical investigations ":

(1) Western medicine diagnose standard: in normal diet situation, 2 weeks interior survey for 2 times serum total cholesterol (TC) all >=6.0mmol/L (230mg/dL), or triglyceride (TG) >=1.54mmol/L (140mg/dL), or HDL-C (HDL-C) man≤1.04mmol/L (40mg/dL), female≤1.17mmol/L (45mg/dL) person.

(2) Standards of Chinese Medical Syndrome Differentiation: fat, limbs are tired heavy, and chest and diaphragm is full vexed, and abundant expectoration drowsiness, pale tongue with white fur is greasy, stringy and rolling pulse.

3, Therapeutic Method

3.1 prescriptions: Fici hispidae 35g, Caulis Benincasae 25g, Radix Gentianae 25g, Radix Platycodonis 25g, Radix Incarvilleae compactae 20g, photooxidative stress 20g, Rhizoma Atractylodis Macrocephalae 20g, Pericarpium Citri Reticulatae 20g, Radix Et Rhizoma Rhei 12g, Bombyx Batryticatus 3g.

3.2 preparation methoies: said medicine routinely technique makes decoction.

3.3 instructions of taking: each 1 dose, every day 2 times 30 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 with reference to " new Chinese medicine guideline of clinical investigations ":

Clinical cure: clinical symptoms, sign disappear, the every inspection of laboratory recovers normal.

Effective: clinical symptoms, sign disappear substantially, lipids detection reaches following any one person: TC decline >=20%, TG decline >=40%, HDL-C rising >=0.26mmol/L (10mg/dL), TC-HDL-C/HDL-C decline >=20%.

Effective: clinical symptoms, sign all take a favorable turn, lipids detection reaches following any one person: TC declines >=10% but < 20%, TG declines >=20% but < 40%, HDL-C rising >=0.104mmol/L (4mg/dL) but < 0.26mmol/L (10mg/dL), TC-HDL-C/HDL-C decline >=10% but < 20%.

Invalid: symptom, sign and the lipids detection person of being not improved after treatment.

4.2 results: in 64 routine patients, cure 35 examples (54.7%), effective 14 examples (21.9%), effective 10 examples (15.6%), and do not heal 5 examples (7.8%), and total effective rate is 92.2%.

5, model case

5.1 men, 48 years old, uncomfortable in chest, spiritlessness and weakness, distension and fullness in the abdomen, indigestion and loss of appetite loose stool, soreness of the waist and knees, abundant expectoration, pale tongue with white fur, rolling pulse.On inspection, serum total cholesterol (TC) 7.43mmol/L, triglyceride (TG) 3.18mmol/L.Take Chinese medicine of the present invention to treat, after treating 2 courses for the treatment of, all diseases disappear all, serum total cholesterol (TC) 5.17mmol/L, triglyceride (TG) 1.06mmol/L, recovery from illness.

5.2 female, 51 years old, dizzy, uncomfortable in chest, breathe hard, numb limbs and tense tendons, asthenia, red tongue have that ecchymosis is white, rolling pulse.On inspection, serum total cholesterol (TC) 8.21mmol/L, triglyceride (TG) 3.16mmol/L.Take the Chinese medicine that the present invention treats essential resistance of turbid phlegm type hyperlipemia to treat, after treating 2 courses for the treatment of, all diseases disappear all, serum total cholesterol (TC) 5.05mmol/L, triglyceride (TG) 1.18 mmol/L, recovery from illness.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.

Embodiment 1, a kind of Chinese medicine for the treatment of essential resistance of turbid phlegm type hyperlipemia, it is made up of following raw material medicaments: Fici hispidae 30g, Caulis Benincasae 20g, Radix Gentianae 20g, Radix Platycodonis 20g, Radix Incarvilleae compactae 15g, photooxidative stress 15g, Rhizoma Atractylodis Macrocephalae 15g, Pericarpium Citri Reticulatae 15g, Radix Et Rhizoma Rhei 10g, Bombyx Batryticatus 2g.

Embodiment 2, a kind of Chinese medicine for the treatment of essential resistance of turbid phlegm type hyperlipemia, it is made up of following raw material medicaments: Fici hispidae 35g, Caulis Benincasae 25g, Radix Gentianae 25g, Radix Platycodonis 25g, Radix Incarvilleae compactae 20g, photooxidative stress 20g, Rhizoma Atractylodis Macrocephalae 20g, Pericarpium Citri Reticulatae 20g, Radix Et Rhizoma Rhei 12g, Bombyx Batryticatus 3g.

Embodiment 3, a kind of Chinese medicine for the treatment of essential resistance of turbid phlegm type hyperlipemia, it is made up of following raw material medicaments: Fici hispidae 40g, Caulis Benincasae 30g, Radix Gentianae 30g, Radix Platycodonis 30g, Radix Incarvilleae compactae 25g, photooxidative stress 25g, Rhizoma Atractylodis Macrocephalae 25g, Pericarpium Citri Reticulatae 25g, Radix Et Rhizoma Rhei 15g, Bombyx Batryticatus 5g.

Claims (2)

1. treat a Chinese medicine for essential resistance of turbid phlegm type hyperlipemia, it is characterized in that being made up of following crude drug:

Fici hispidae 30-40 part, Caulis Benincasae 20-30 part, Radix Gentianae 20-30 part, Radix Platycodonis 20-30 part,

Radix Incarvilleae compactae 15-25 part, photooxidative stress 15-25 part, Rhizoma Atractylodis Macrocephalae 15-25 part, Pericarpium Citri Reticulatae 15-25 part,

Radix Et Rhizoma Rhei 10-15 part, Bombyx Batryticatus 2-5 part.

2. Chinese medicine according to claim 1, is characterized in that being made up of following crude drug:

Fici hispidae 35 parts, Caulis Benincasae 25 parts, Radix Gentianae 25 parts, Radix Platycodonis 25 parts,

Radix Incarvilleae compactae 20 parts, photooxidative stress 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Pericarpium Citri Reticulatae 20 parts,

Radix Et Rhizoma Rhei 12 parts, Bombyx Batryticatus 3 parts.