CN104687098A - Crocodile composite capable of lowering blood glucose and preparation method thereof - Google Patents
Crocodile composite capable of lowering blood glucose and preparation method thereof Download PDFInfo
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- CN104687098A CN104687098A CN201510144164.6A CN201510144164A CN104687098A CN 104687098 A CN104687098 A CN 104687098A CN 201510144164 A CN201510144164 A CN 201510144164A CN 104687098 A CN104687098 A CN 104687098A
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Abstract
The invention discloses a crocodile composite capable of lowering blood glucose. Every 100 parts of the crocodile composite comprises, by weight, 3-10 parts of crocodile meat extract, 40-55 parts of folium mori and 40-50 parts of cinnamon. The crocodile composite can lower blood glucose. The invention further provides a preparation method of the crocodile composite.
Description
Technical field
The present invention relates to crocodile arts, particularly one and can fall hypoglycemic crocodile composite and preparation method thereof.
Background technology
Crocodile is a kind of ancient reptile, all has the record about crocodile medical value in the ancient medicine ancient books and records such as Compendium of Material Medica.The record to crocodile first is just had: " taste is pungent, tepor as far back as the Collective Notes to the Canon of Materia medica in Northern and Southern Dynasties periods.Main heart abdomen Disorder lump in the abdomen, Fu Jian, gather, fever and chills." supplement to the Herbal claims Chinese alligator first " main evil sore, Fu Nei Disorder lump in the abdomen ".Compendium of Material Medica " squamosa " the 43 volume of Ming Dynasty's Li Shizhen (1518-1593 A.D.) then describes in detail: " Chinese alligator (i.e. crocodile) first cures mainly trusted subordinate's abdominal mass; Fu Jian gathers; Meat: cure mainly weak breath and inhale, foot is not on the spot; Not Lu moisture perverse trend, abdominal mass in all legendary venomous insects, dislike blister.Fat: cure mainly and rub wind and dislike sore." in modern science and technology, crocodile meat, crocodile courage have been widely used in health care and medical field.
Prior art is fully excavating the significant market potential of crocodile goods, but the application of crocodile meat still has a lot of place not obtain correct understanding and exploitation.
Summary of the invention
The invention provides one and can fall hypoglycemic crocodile composite, the present invention also provides the preparation method of above-mentioned composition.
Technical scheme provided by the invention is: hypoglycemic crocodile composite can fall in one, and every 100 weight portions comprise the component of following weight portion:
Crocodile meat extract: 3 ~ 10 parts;
Mulberry leaf: 40 ~ 55 parts;
Chinese cassia tree: 40 ~ 50 parts.
Can fall in hypoglycemic crocodile composite above-mentioned, every 100 weight portions comprise the component of following weight portion:
Crocodile meat extract: 5 ~ 9 parts;
Mulberry leaf: 45 ~ 50 parts;
Chinese cassia tree: 45 ~ 50 parts.
The present invention also provides the above-mentioned preparation method that can fall hypoglycemic crocodile composite, comprises the following steps:
Step 1: preparation crocodile meat extract, grinds to form mulberry leaf powder and ground cinnamon by after mulberry leaf, Chinese cassia tree drying;
Step 2: crocodile meat extract, mulberry leaf powder and ground cinnamon are mixed, dry and granulation.
Can fall in the preparation method of hypoglycemic crocodile composite above-mentioned, the preparation method of described crocodile meat extract has and comprises:
1) take crocodile flesh of fish, grind, 1:1 adds water in mass ratio, boils rear maintenance 15min and is placed on 4 DEG C of coolings, is removed by the grease of cooling after coagulation in upper strata, prepares muddy flesh;
2) mass ratio muddy flesh and distilled water being pressed 1:1 loads in flask, is placed in water bath with thermostatic control and carries out enzymolysis 1-5h;
3), after enzymolysis terminates, in 80 DEG C of water-baths, be incubated 20min make enzyme deactivation;
4) enzymolysis liquid after the enzyme that goes out is cooled to room temperature, removes unhydrolysed muddy flesh, then at 4 DEG C, 10000r/min centrifugation 15min, removing solid matter, collects supernatant, utilizes vacuum freeze drier to be lyophilized into powder.
Beneficial effect of the present invention is:
The present invention adopts the mulberry leaf having and reduce blood sugar and blood fat, and 5 join crocodile meat extract and Chinese cassia tree, has good to fall hypoglycemic effect, and natural material has no side effect to human body fanout free region simultaneously.
Detailed description of the invention
Below in conjunction with detailed description of the invention, technical scheme of the present invention is described in further detail, but does not form any limitation of the invention.
The preparation method of crocodile meat extract
1) take the meat of safe crocodile, grind, 1:1 adds water in mass ratio, boils rear maintenance 15min and is placed on 4 DEG C of coolings, is removed by the grease of cooling after coagulation in upper strata, prepares muddy flesh;
2) mass ratio muddy flesh and distilled water being pressed 1:1 loads in flask, is placed in water bath with thermostatic control and carries out enzymolysis 1-5h;
3), after enzymolysis terminates, in 80 DEG C of water-baths, be incubated 20min make enzyme deactivation;
4) enzymolysis liquid after the enzyme that goes out is cooled to room temperature, removes unhydrolysed muddy flesh, then at 4 DEG C, 10000r/min centrifugation 15min, removing solid matter, collects supernatant, utilizes vacuum freeze drier to be lyophilized into powder.
Embodiment 1
Get crocodile meat extract: 5g; Mulberry leaf powder: 50g; Ground cinnamon: 45g; Wherein first mulberry leaf and Chinese cassia tree need to be dried to water content lower than 8%, then adopt the method for grinding that mulberry leaf are ground to 40 orders, Chinese cassia tree are ground to 80-100 order, obtain mulberry leaf powder and ground cinnamon.
After crocodile meat extract, mulberry leaf powder, ground cinnamon are mixed, by vacuum drier drying and granulating.Obtain sample 1.
Embodiment 2:
Get crocodile meat extract: 3g; Mulberry leaf powder: 55g; Ground cinnamon: 42g; Wherein first mulberry leaf and Chinese cassia tree need to be dried to water content lower than 8%, then adopt the method for grinding that mulberry leaf are ground to 40 orders, Chinese cassia tree are ground to 80-100 order, obtain mulberry leaf powder and ground cinnamon.
After crocodile meat extract, mulberry leaf powder, ground cinnamon are mixed, by vacuum drier drying and granulating.
Embodiment 3:
Get crocodile meat extract: 9g; Mulberry leaf powder: 50g; Ground cinnamon: 41g; Wherein first mulberry leaf and Chinese cassia tree need to be dried to water content lower than 8%, then adopt the method for grinding that mulberry leaf are ground to 40 orders, Chinese cassia tree are ground to 80-100 order, obtain mulberry leaf powder and ground cinnamon.
After crocodile meat extract, mulberry leaf powder, ground cinnamon are mixed, by vacuum drier drying and granulating.
Comparative example 1:
Get mulberry leaf powder: 50g; Ground cinnamon: 50g; Wherein first mulberry leaf and Chinese cassia tree need to be dried to water content lower than 8%, then adopt the method for grinding that mulberry leaf are ground to 40 orders, Chinese cassia tree are ground to 80-100 order, obtain mulberry leaf powder and ground cinnamon.
After mulberry leaf powder, ground cinnamon are mixed, by vacuum drier drying and granulating.Obtain contrasting sample 1
The test of pesticide effectiveness of the present invention is as follows:
Select patients with NIDDM 35 people, the wherein male sex 25 people, women 10 people, the range of age be 48-58 year, 55 years old mean age, diabetic history 3-18, average 8 years.Subject is divided into two groups at random, experimental group and control group, experimental group 18 people, control group 17 people.Experimental group morning, noon and afternoon every day are divided into takes above-mentioned sample 1 for three times, and each 3-4g, takes 3 months continuously; Control group morning, noon and afternoon every day are divided into takes above-mentioned contrast sample 1 for three times, and each 3-4g, takes 3 months continuously; Period eating habit, work and rest custom, supporting hypoglycemic drug takes and all do not change, by normal life routine life.
Result of the test is as follows:
Can be found out by upper table, experimental group and control group all serve and fall hypoglycemic effect, but experimental group is after adding crocodile meat extract component, can improve the control of mulberry leaf to blood sugar significantly.This effect along with the prolongation of time particularly remarkable.
Above-describedly be only preferred embodiment of the present invention, all do within the scope of the spirit and principles in the present invention any amendment, equivalently to replace and improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. can fall a hypoglycemic crocodile composite, it is characterized in that, every 100 weight portions comprise the component of following weight portion:
Crocodile meat extract: 3 ~ 10 parts;
Mulberry leaf: 40 ~ 55 parts;
Chinese cassia tree: 40 ~ 50 parts.
2. according to claim 1ly can fall hypoglycemic crocodile composite, it is characterized in that, every 100 weight portions comprise the component of following weight portion:
Crocodile meat extract: 5 ~ 9 parts;
Mulberry leaf: 45 ~ 50 parts;
Chinese cassia tree: 45 ~ 50 parts.
3. can fall a preparation method for hypoglycemic crocodile composite as claimed in claim 1, it is characterized in that, comprise the following steps:
Step 1: preparation crocodile meat extract, grinds to form mulberry leaf powder and ground cinnamon by after mulberry leaf, Chinese cassia tree drying;
Step 2: crocodile meat extract, mulberry leaf powder and ground cinnamon are mixed, dry and granulation.
4. the preparation method that can fall hypoglycemic crocodile composite according to claim 3, is characterized in that, the preparation method of described crocodile meat extract has and comprises:
1) take crocodile flesh of fish, grind, 1:1 adds water in mass ratio, boils rear maintenance 15min and is placed on 4 DEG C of coolings, is removed by the grease of cooling after coagulation in upper strata, prepares muddy flesh;
2) mass ratio muddy flesh and distilled water being pressed 1:1 loads in flask, is placed in water bath with thermostatic control and carries out enzymolysis 1-5h;
3), after enzymolysis terminates, in 80 DEG C of water-baths, be incubated 20min make enzyme deactivation;
4) enzymolysis liquid after the enzyme that goes out is cooled to room temperature, removes unhydrolysed muddy flesh, then at 4 DEG C, 10000r/min centrifugation 15min, removing solid matter, collects supernatant, utilizes vacuum freeze drier to be lyophilized into powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510144164.6A CN104687098B (en) | 2015-03-30 | 2015-03-30 | It is a kind of to reduce crocodile composite of blood glucose and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510144164.6A CN104687098B (en) | 2015-03-30 | 2015-03-30 | It is a kind of to reduce crocodile composite of blood glucose and preparation method thereof |
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| Publication Number | Publication Date |
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| CN104687098A true CN104687098A (en) | 2015-06-10 |
| CN104687098B CN104687098B (en) | 2017-10-10 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106873A (en) * | 2010-04-07 | 2011-06-29 | 北京洪源澳达生物技术发展有限公司 | Crocodile meat extract and preparation method and application thereof |
| CN102266391A (en) * | 2011-07-08 | 2011-12-07 | 广州雅邦生物技术有限公司 | Composition extracted from medicinal and edible plants and able to adjust fasting and postprandial blood glucose simultaneously |
| CN103416768A (en) * | 2013-08-15 | 2013-12-04 | 汪华东 | Ziyin Busheng crocodile meat composition and preparation method thereof |
| CN103907963A (en) * | 2014-04-28 | 2014-07-09 | 陈杰凡 | Crocodile meat sausage |
-
2015
- 2015-03-30 CN CN201510144164.6A patent/CN104687098B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106873A (en) * | 2010-04-07 | 2011-06-29 | 北京洪源澳达生物技术发展有限公司 | Crocodile meat extract and preparation method and application thereof |
| CN102266391A (en) * | 2011-07-08 | 2011-12-07 | 广州雅邦生物技术有限公司 | Composition extracted from medicinal and edible plants and able to adjust fasting and postprandial blood glucose simultaneously |
| CN103416768A (en) * | 2013-08-15 | 2013-12-04 | 汪华东 | Ziyin Busheng crocodile meat composition and preparation method thereof |
| CN103907963A (en) * | 2014-04-28 | 2014-07-09 | 陈杰凡 | Crocodile meat sausage |
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| CN104687098B (en) | 2017-10-10 |
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Effective date of registration: 20200212 Address after: 510000 No.1, Luohu Development Zone, luohang community, Danzao Town, Nanhai District, Foshan City, Guangdong Province (application for residence) Patentee after: Foshan Lukangbao Health Food Co.,Ltd. Address before: 510000, room 515, No. 2305-2306 Dongfeng Road, Guangdong, Guangzhou, Yuexiu District Patentee before: GUANGZHOU SHANKANG BIOTECHNOLOGY CO.,LTD. |
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Effective date of registration: 20220706 Address after: 527300 building 3, plot 05-02 (006), North Park, Xincheng Industrial Park, Xinxing County, Yunfu City, Guangdong Province Patentee after: Lvbao Zhongke (Guangdong) Biotechnology Co.,Ltd. Address before: 510000 No.1 Laohu Development Zone, Luoxing community, Danzao Town, Nanhai District, Foshan City, Guangdong Province, self compiled 001 (residence declaration) Patentee before: Foshan Lukangbao Health Food Co.,Ltd. |