CN104667176A - Traditional Chinese medicine for treating malignant arrhythmia of coronary heart disease - Google Patents
Traditional Chinese medicine for treating malignant arrhythmia of coronary heart disease Download PDFInfo
- Publication number
- CN104667176A CN104667176A CN201510060128.1A CN201510060128A CN104667176A CN 104667176 A CN104667176 A CN 104667176A CN 201510060128 A CN201510060128 A CN 201510060128A CN 104667176 A CN104667176 A CN 104667176A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- herba
- chinese medicine
- heart disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of medicine formulas, and in particular relates to a traditional Chinese medicine for treating malignant arrhythmia of a coronary heart disease. The traditional Chinese medicine is characterized by being prepared from the following raw materials in parts by weight: 5-9 parts of stellaria yunnanensis, 4-7 parts of ophiopogon latifolius, 4-8 parts of aleppo avens, 4-7 parts of odontoglossum crispum, 4-8 parts of curcuma aromatic, 5-8 parts of loranthus parasiticus, 6-9 parts of paris polyphylla, 6-9 parts of terminalia arjuna skin, 7-9 parts of semen pharbitidis, 6-9 parts of inula flower, 2-5 parts of herminium lanceum, 6-9 parts of cudrania cochinchinensis, 2-5 parts of juncus effuses, 4-6 parts of tuber fleeceflower stem, 2-4 parts of ageratum conyzoides, 4-6 parts of dendrobe, 2-4 parts of clematis kerriana and 7-9 parts of sanguisorba officinalis. The traditional Chinese medicine for treating malignant arrhythmia of the coronary heart disease has the advantages of significant curative effect, low cost, and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine being used for the treatment of coronary heart disease malignant arrhythmia.
Background technology
As everyone knows, malignant arrhythmia mainly refers to quiver in the room speed of hemodynamic instability and room, and being the major reason of dying suddenly, is also the lethal one of the main reasons of coronary heart disease and arrhythmia patient.Most of malignant arrhythmia is with organic heart disease (as coronary heart disease, cardiomyopathy, heart failure etc.).Multiple clinical trial confirms that amiodarone can control the outbreak of malignant arrhythmia effectively in recent years, improves the effect of electrical conversion, reduces arrhythmia and general mortality rate.QT dispersion (QTd) significant prolongation in coronary heart disease malignant arrhythmia patient, and closely related with malignant arrhythmia.Amiodarone is the common drug for the treatment of Identifying Patients of Ventricular Arrhythmias With Coronary Artery Disease, and in the short time, the heavy dose of amiodarone of quiet note often proves effective, but long-term treatment, then there is larger side effect
Summary of the invention
Object of the present invention is exactly to overcome above-mentioned existing technical deficiency, provides a kind of evident in efficacy, with low cost, Chinese medicine for the treatment of coronary heart disease malignant arrhythmia of having no side effect.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine being used for the treatment of coronary heart disease malignant arrhythmia, it is characterized in that being made up of the crude drug of following weight portion: Radix Stellariae Yunnanensis 5 ~ 9, Radix Ophiopogonis Dracaenoidis 4 ~ 7, Radix seu Herba Gei aleppici 4 ~ 8, Herba Orchidis Latifoliae 4 ~ 7, Radix Curcumae 4 ~ 8, Herba Taxilli 5 ~ 8, Rhizoma Paridis 6 ~ 9, Fructus Phyllanthi veneer 6 ~ 9, Semen Pharbitidis 7 ~ 9, Flos Inulae 6 ~ 9, kidney grass 2 ~ 5, Radix Cudraniae 6 ~ 9, Medulla Junci 2 ~ 5, Caulis Polygoni Multiflori 4 ~ 6, Herba Agerati Conyzoidis 2 ~ 4, Herba Dendrobii 4 ~ 6, Clematis kerriana Drumm. Et Craiab 2 ~ 4, Radix Sanguisorbae 7 ~ 9, by medicinal for above-mentioned raw materials water soaking, to remove slag after decocting to obtain filtrate.
The invention has the beneficial effects as follows, the advantages such as treatment coronary heart disease malignant arrhythmia is evident in efficacy, with low cost, without any side effects.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Radix Stellariae Yunnanensis, Radix Ophiopogonis Dracaenoidis, Radix seu Herba Gei aleppici, Herba Orchidis Latifoliae, Radix Curcumae, Herba Taxilli, Rhizoma Paridis, Fructus Phyllanthi veneer, Semen Pharbitidis, Flos Inulae, kidney grass, Radix Cudraniae, Medulla Junci, Caulis Polygoni Multiflori, Herba Agerati Conyzoidis, Herba Dendrobii, Clematis kerriana Drumm. Et Craiab, Radix Sanguisorbae is adopted to be that raw material is prepared from.The every pair of its component (weight) is Radix Stellariae Yunnanensis 7, Radix Ophiopogonis Dracaenoidis 6, Radix seu Herba Gei aleppici 6, Herba Orchidis Latifoliae 5, Radix Curcumae 6, Herba Taxilli 6, Rhizoma Paridis 7, Fructus Phyllanthi veneer 7, Semen Pharbitidis 8, Flos Inulae 7, kidney grass 4, Radix Cudraniae 8, Medulla Junci 3, Caulis Polygoni Multiflori 5, Herba Agerati Conyzoidis 3, Herba Dendrobii 5, Clematis kerriana Drumm. Et Craiab 3, Radix Sanguisorbae 8.Get above-mentioned 18 taste raw materials, gross weight is 176 grams, add water 800 ~ 900 milliliters and at room temperature soak 5 ~ 6 hours, slow fire decocted to 60 ~ 80 minutes, filtrate about 150 milliliters of removing slag to obtain, and medicinal residues add water 200 ~ 300ml again, decoct 20 ~ 30 minutes, to remove slag to obtain filtrate 50 ~ 70 milliliters, altogether the medicine juice of about 200 ~ 220 milliliters, i.e. obtained decoction of the present invention.Load in sterile glass vials, seal bottle cap is for subsequent use, and every day 1 dose point 2 times is oral, sooner or later respectively once, and each (medicine) being taken before meal 100 ~ 110 milliliters.
Radix Stellariae Yunnanensis of the present invention controls the empty anemia of body, and spirit is deficient, dizzy nervous; Radix Ophiopogonis Dracaenoidis centering is calmed the nerves, and relieving cough and resolving phlegm, controls cardiopalmus, rheumatic heart disease; Radix seu Herba Gei aleppici eases pain, blood pressure lowering, regulating menstruation, expelling wind and removing dampness.For hypertension, dizziness headache; Herba Orchidis Latifoliae nourishing heart and kidney, promoting the production of body fluid to quench thirst, strengthening the spleen and stomach; Radix Curcumae has the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire; Herba Taxilli has wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, antiabortive effect; Rhizoma Paridis has heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the effect of liver arresting convulsion of drying in the air; Fructus Phyllanthi veneer inrigorating qi and promoting blood circulation, removing toxic substances sore.Main body void is weak, shortness of breath and palpitation; Semen Pharbitidis is applicable to ascites, abdominal distention constipation, ascariasis etc.; Flos Inulae sending down the abnormal ascending QI, expectorant, row water, preventing or arresting vomiting.For cough due to wind and cold, phlegm retention stores knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, vomiting eructation, epigastric oppression and rigidity; Kidney grass nourishes blood tonify deficiency, dehumidifying of regulating the flow of vital energy.Main asthenia, eyes is dim-sighted; Radix Cudraniae relieving cough and resolving phlegm, expelling wind and removing dampness, eliminating stasis to stop pain; Medulla Junci controls gonorrhea, edema, dysuria, jaundice due to damp-heat, dysphoria and insomnia; Caulis Polygoni Multiflori nourishes heart, and calms the nerves, and dredging collateral dispels the wind, and controls insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain; Herba Agerati Conyzoidis heat-clearing and toxic substances removing, detumescence hemostasis; Herba Dendrobii reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill; Clematis kerriana Drumm. Et Craiab heat-clearing and toxic substances removing, diuresis, eliminating blood stasis and smoothing collaterals; The effects such as Radix Sanguisorbae has cooling blood for hemostasis, heat-clearing and toxic substances removing, trains clear yin nourishing, detumescence sore.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize.Its processing technique is identical with embodiment 1.
| Embodiment | Radix Stellariae Yunnanensis | Radix Ophiopogonis Dracaenoidis | Radix seu Herba Gei aleppici | Herba Orchidis Latifoliae | Radix Curcumae | Herba Taxilli | Rhizoma Paridis | Fructus Phyllanthi veneer | Semen Pharbitidis | Flos Inulae | Kidney grass | Radix Cudraniae | Medulla Junci | Caulis Polygoni Multiflori | Herba Agerati Conyzoidis | Herba Dendrobii | Clematis kerriana Drumm. Et Craiab | Radix Sanguisorbae |
| Two | 9 | 7 | 4 | 7 | 4 | 8 | 6 | 9 | 7 | 9 | 3 | 9 | 2 | 6 | 2 | 6 | 2 | 7 |
| Three | 9 | 4 | 8 | 4 | 8 | 5 | 9 | 6 | 9 | 6 | 5 | 6 | 5 | 4 | 4 | 4 | 4 | 9 |
| Four | 5 | 6 | 7 | 6 | 5 | 7 | 8 | 8 | 8 | 9 | 2 | 9 | 4 | 5 | 3 | 5 | 3 | 8 |
| Five | 8 | 5 | 7 | 5 | 7 | 6 | 7 | 7 | 8 | 7 | 4 | 7 | 3 | 5 | 4 | 6 | 4 | 7 |
The clinical trial carried out below in conjunction with my institute is done further the present invention, is described in detail:
1. data and method
1.1 physical data
All patients all meets the diagnostic criteria that WHO recommends, and is divided into two groups at random.Treatment group 35 example, male 21 example, women 14 example; Age (59.12 ± 11 years old); Sick 22 examples of accompanied with hypertension, type 2 diabetes mellitus 12 example, hyperlipemia 17 example.Matched group 36 example, male 26 example, women 10 example; Age (57.664 ± 10.48) year: sick 17 examples of accompanied with hypertension, 2 type glycosurias 11 examples, hyperlipemia 20 example.Two groups of physical data no significant differences (P > 0.05).
1.2 Therapeutic Method
All take a routine treatment after patient people institute, intravenous amiodarone loading 3 ~ 5mg/kg, quiet note in 10min after dilution, vein maintenance dose is starting dose 1.0 ~ 1.5mg/min, according to state of an illness adjustment dosage; Auxiliary etiological treatment (polarized solution, aspirin, Statins, nitrate esters, ACEI and B receptor blocking agent), treatment group gives medicine of the present invention in the 1st day after amiodarone on treating, every day 1 dose point 2 times is oral, sooner or later each once, each (medicine) being taken before meal 100 ~ 110 milliliters.Matched group is treated routinely.
Be 30 days the course for the treatment of.
1.3 observational technique
Often organize during medication and detect 12 lead electrocardiogram every day, except T, V wavelength-division circle is unclear or T ripple low flat lead outside, each measurement 3 Q-T that lead, interval, gets its meansigma methods, deducts the shortest QT interval be QTdo from the QT interval that difference is led the longest
1.4 statistical procedures
Application SPSS10.0 statistical software, measurement data represents with (X ± s), adopts X2 inspection and t inspection.
2. result
QT dispersion level close (P > 0.05) during two groups of patient admits
2.1 liang of group treatments period QT dispersion levels compare in table 1.
Table 1 treatments period QT dispersion level compares
| Group | Latter 1st day for the treatment of | Latter 7th day for the treatment of | Latter 15th day for the treatment of | Latter 30th day for the treatment of |
| Treatment group 35 example | 80.15±13.25 | 45.18±11.25 | 31.23±10.43 | 35.31±9.57 |
| Matched group 36 example | 85.35±25.06 | 67.28±18.19 | 59.63±15.74 | 47.36±13.24 |
After treatment the 1st day, two groups of QT dispersion levels all raised obviously, but two groups are compared difference there are no significant (P > 0.05); Later the 7th, 15,30 day two groups compare difference and all have significant difference (P < 0.01).
Treatment group on 7th compared with the 1st day, QT dispersion starts obviously to decline front and back significant difference (P < 0.05), until the 15th, the 30th compares, QT dispersion but still significantly lower than (P < 0.01) on the 1st.
Matched group on 7th compared with the 1st day, QT dispersion starts to decline, front and back difference has statistical significance (P < 0.05), but QT dispersion level level had declined not obvious (P > 0.05) compared with the 15th, the 30th on 1;
3. conclusion
Confirmed by above clinical trial, medicine of the present invention obviously can reduce the QT dispersion level of coronary heart disease malignant arrhythmia patient, determined curative effect, and therefore, medicine of the present invention effectively can treat coronary heart disease malignant arrhythmia.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of coronary heart disease malignant arrhythmia, it is characterized in that being made up of the crude drug of following weight portion: Radix Stellariae Yunnanensis 5 ~ 9, Radix Ophiopogonis Dracaenoidis 4 ~ 7, Radix seu Herba Gei aleppici 4 ~ 8, Herba Orchidis Latifoliae 4 ~ 7, Radix Curcumae 4 ~ 8, Herba Taxilli 5 ~ 8, Rhizoma Paridis 6 ~ 9, Fructus Phyllanthi veneer 6 ~ 9, Semen Pharbitidis 7 ~ 9, Flos Inulae 6 ~ 9, kidney grass 2 ~ 5, Radix Cudraniae 6 ~ 9, Medulla Junci 2 ~ 5, Caulis Polygoni Multiflori 4 ~ 6, Herba Agerati Conyzoidis 2 ~ 4, Herba Dendrobii 4 ~ 6, Clematis kerriana Drumm. Et Craiab 2 ~ 4, Radix Sanguisorbae 7 ~ 9, by medicinal for above-mentioned raw materials water soaking, filtrate of removing slag after decocting to obtain.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510060128.1A CN104667176A (en) | 2015-02-05 | 2015-02-05 | Traditional Chinese medicine for treating malignant arrhythmia of coronary heart disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510060128.1A CN104667176A (en) | 2015-02-05 | 2015-02-05 | Traditional Chinese medicine for treating malignant arrhythmia of coronary heart disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104667176A true CN104667176A (en) | 2015-06-03 |
Family
ID=53303112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510060128.1A Pending CN104667176A (en) | 2015-02-05 | 2015-02-05 | Traditional Chinese medicine for treating malignant arrhythmia of coronary heart disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104667176A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213718A (en) * | 2015-10-15 | 2016-01-06 | 岳宏丽 | For the Chinese medicine composition of malignant arrhythmia |
| CN105434885A (en) * | 2016-01-27 | 2016-03-30 | 刘兆英 | Traditional Chinese medicine for treating Yin-deficiency and fire-excess type arrhythmia and preparation method |
| CN105726940A (en) * | 2016-04-05 | 2016-07-06 | 赵云 | Traditional Chinese medicine composition for treating coronary heart disease malignant arrhythmia |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102210757A (en) * | 2010-04-08 | 2011-10-12 | 河北以岭医药研究院有限公司 | Application of Chinese medicine composition in preparation of medicine for treating coronary heart disease malignant arrhythmia |
| CN102973887A (en) * | 2012-11-15 | 2013-03-20 | 安徽同泰药业有限公司 | Traditional Chinese medicine used for treating arrhythmia |
| CN103877512A (en) * | 2014-04-01 | 2014-06-25 | 青岛市中心医院 | Traditional Chinese medicine for treating arrhythmia and preparation method thereof |
-
2015
- 2015-02-05 CN CN201510060128.1A patent/CN104667176A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102210757A (en) * | 2010-04-08 | 2011-10-12 | 河北以岭医药研究院有限公司 | Application of Chinese medicine composition in preparation of medicine for treating coronary heart disease malignant arrhythmia |
| CN102973887A (en) * | 2012-11-15 | 2013-03-20 | 安徽同泰药业有限公司 | Traditional Chinese medicine used for treating arrhythmia |
| CN103877512A (en) * | 2014-04-01 | 2014-06-25 | 青岛市中心医院 | Traditional Chinese medicine for treating arrhythmia and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 张景义 等: "平律煎治疗心律失常45例", 《陕西中医》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213718A (en) * | 2015-10-15 | 2016-01-06 | 岳宏丽 | For the Chinese medicine composition of malignant arrhythmia |
| CN105434885A (en) * | 2016-01-27 | 2016-03-30 | 刘兆英 | Traditional Chinese medicine for treating Yin-deficiency and fire-excess type arrhythmia and preparation method |
| CN105726940A (en) * | 2016-04-05 | 2016-07-06 | 赵云 | Traditional Chinese medicine composition for treating coronary heart disease malignant arrhythmia |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104383390A (en) | Chinese traditional medicine preparation for treating lung cancer | |
| CN104667176A (en) | Traditional Chinese medicine for treating malignant arrhythmia of coronary heart disease | |
| CN103463516B (en) | Traditional Chinese medicine ointment for treating dermatophytoses and preparation method thereof | |
| CN102886031A (en) | Traditional Chinese medicine for treating hyperplasia of mammary glands and preparation method of traditional Chinese medicine | |
| CN101874850B (en) | Medicament for treating chronic urticaria | |
| CN105311460A (en) | Traditional Chinese medicine for treating vascular neuralgia headache | |
| CN101564522A (en) | Chinese medicament for treating intercostal nerve pain and preparation method thereof | |
| CN101983645A (en) | Medicament for treating acute appendicitis | |
| CN103893675A (en) | Traditional Chinese medicinal preparation for treating epigastric pain | |
| CN112206279B (en) | Traditional Chinese medicine composition for treating ventricular arrhythmia and preparation method and application thereof | |
| CN116570699B (en) | Traditional Chinese medicine composition for treating pulmonary nodules as well as preparation and application thereof | |
| CN102772723A (en) | Chinese medicinal prescription for treating phthisis | |
| CN105213718A (en) | For the Chinese medicine composition of malignant arrhythmia | |
| CN102228661B (en) | Chinese medicinal cholecystitis treatment mixture for treating chronic cholecystitis | |
| CN105343777A (en) | Heart soothing pills and method for preparing same | |
| CN106344850A (en) | Traditional Chinese medicine composition for treating diabetic foot | |
| CN106421614A (en) | Spleen-invigorating, collateral-dredging and detoxifying traditional Chinese medicinal capsule | |
| CN106421613A (en) | Spleen-invigorating, collateral-dredging and detoxifying traditional Chinese medicinal composition and preparation method and traditional Chinese medicinal preparation thereof | |
| CN105687542A (en) | Chinese herbal preparation for fracture aftertreatment and preparing method thereof | |
| CN107050298A (en) | A kind of Chinese medicine paste formulation and preparation method for treating burn and scald skin damaged | |
| CN104758541A (en) | Traditional Chinese medicine for treating lymphoma | |
| CN112915179A (en) | Traditional Chinese medicine for promoting blood circulation to remove blood stasis | |
| CN103720916A (en) | Tea extract for relieving thrombocytopenic purpura caused by radiation and preparation method thereof | |
| CN102078387A (en) | Traditional Chinese medicine for treating fibroid and ovarian cyst | |
| CN107596335A (en) | A kind of mammary gland external traditional Chinese medicine oil and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150603 |