CN104666536A

CN104666536A - Internally-used traditional Chinese medicinal composition for treating migraine

Info

Publication number: CN104666536A
Application number: CN201510109656.1A
Authority: CN
Inventors: 李海霞; 杨志峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-03-08
Filing date: 2015-03-08
Publication date: 2015-06-03

Abstract

The invention relates to an internally-used traditional Chinese medicinal composition for treating migraine, and belongs to the field of traditional Chinese medicines. The internally-used traditional Chinese medicinal composition is characterized by being prepared from the following traditional Chinese medicinal raw materials in part by weight: 25 parts of ligusticum wallichii, 20 parts of notopterygium, 15 parts of hematoxylon, 15 parts of fructus evodiae, 9 parts of radix angelicae, 5 parts of asarum, 9 parts of ligusticum, 9 parts of radix bupleuri, 12 parts of white peony root and 10 parts of liquorice. The internally-used traditional Chinese medicinal composition has the effects of expelling wind and removing cold, dredging collaterals and removing humidity, and removing stasis and stopping pains, has a remarkable effect of treating the migraine, and is stable in therapeutic effect and free of toxic or side effects.

Description

The migrainous Chinese medicine composition of a kind of orally taken for curing

Technical field:

The present invention relates to the migrainous Chinese medicine composition of a kind of orally taken for curing, belong to the field of Chinese medicines.

Background technology:

Migraine is modal one in primary headache.Its incidence rate is high, accounts for greatly in headache.Along with the quickening of people's rhythm of life, the increase of social pressure, its prevalence also raises gradually, greatly reduces work and the quality of life of patient groups.

Migraine main manifestations is the cephalic pain of recurrent exerbation, or left or right, even bilateral pain, is often sense of heaviness, constriction, lock ring sense, feeling of numbness, can with nausea and vomiting, and headache character can be dull pain, distending pain, vexed pain, dull pain, twinge.At present, modern medicine thinks that migraine is the headache of a kind of ictal primary neurovascular, and its cause of disease is still not clear, may be relevant with the factor such as heredity, endocrine, metabolism, spirit, diet.Primary disease is multiple is born in the young and the middle aged, and female patient is in the majority.

Modern medical therapy migraine mainly comprises Drug therapy and non-drug therapy two aspects.Non-drug therapy mainly contains magnetic therapy, oxygen therapy, psychological counseling, relieving stress, the life style of keeping fit, avoids various migraine inducements etc.Drug treatment is many because curative effect is unstable, drug dependence is strong, toxic and side effects is large, relapse rate is high, and in clinical practice, have larger restriction.

Summary of the invention:

Technical problem to be solved by this invention is to provide the migrainous Chinese medicine composition of a kind of orally taken for curing.

The present invention is achieved by the following technical solutions.The migrainous Chinese medicine composition of a kind of orally taken for curing, is characterized in that being made up of the raw material of Chinese medicine of following parts by weight:

Rhizoma Chuanxiong 25, Rhizoma Et Radix Notopterygii 20, Lignum Sappan 15, Fructus Evodiae 15, the Radix Angelicae Dahuricae 9, Herba Asari 5, Rhizoma Ligustici 9, Radix Bupleuri 9, the Radix Paeoniae Alba 12, Radix Glycyrrhizae 10.

Single dose dose (unit: gram): Rhizoma Chuanxiong 25, Rhizoma Et Radix Notopterygii 20, Lignum Sappan 15, Fructus Evodiae 15, the Radix Angelicae Dahuricae 9, Herba Asari 5, Rhizoma Ligustici 9, Radix Bupleuri 9, the Radix Paeoniae Alba 12, Radix Glycyrrhizae 10.

Preparation and instructions of taking: be decocted in water for oral dose, every day potion, sooner or later one after each meal at twice 30 days is a course for the treatment of.

Rhizoma Chuanxiong blood-activating and qi-promoting in side of the present invention, wind-expelling pain-stopping; Notopterygium wind dispelling removing dampness to relieve pain; Lignum Sappan promoting blood circulation, removing blood stasis and relieving pain; Fructus Evodiae cold expelling removing obstruction in the collateral to relieve pain, above four Chinese medicine shares as principal agent.The Radix Angelicae Dahuricae, Herba Asari, Rhizoma Ligustici be pungent loose up, the expelling wind and cold of energy all, can strengthen the power of evacuation; Radix Bupleuri priming enters few sun, and medicine-carried rises floating, and through women's head-ornaments are ministerial drug altogether.Radix Paeoniae Alba yin fluid astringing and anti-above all medicines pungent loose too, having again the length of relieving spasm to stop pain, is adjuvant drug.Radix Glycyrrhizae is alleviated urgent, and coordinating the actions of various ingredients in a prescription, for making medicine.All medicines share the merit of playing expelling wind and cold, dredging collateral removing dampness, blood-activating analgetic altogether, and make the state of an illness to healing.

Below in conjunction with clinical trial and model case, the present invention will be further described.

One, clinical trial

1, clinical data: choose migraineur 100 example, male 31 example, women 69 example, the age is between 35 ~ 55 years old.

2, Therapeutic Method: treatment group takes medicine of the present invention, is decocted in water for oral dose, potion, divided twice one after each meal sooner or later, within 30 days, was a course for the treatment of, takes a course for the treatment of altogether every day.

3, clinical observation on the therapeutic effect:

Patient all records headache degree, seizure frequency, persistent period and simultaneous phenomenon etc. afterwards in 30 days with medication before starting the course for the treatment of, and calculates integration.

(1) headache degree

Need lie in bed during outbreak is 6 points, and the work that affects during outbreak is 4 points, and the work that do not affect during outbreak is 2 points.

(2) Headache attacks frequency

Calculate with the moon, monthly outbreak is 6 points for more than 5 times, is 4 points for 3 ~ 4 times, is 2 points for less than 2 times.

(3) have a headache the persistent period

Continue within more than 2 days, be 6 points, continue 12 little be 4 points up to 2 days, being less than 12 hours is 2 points.

(4) simultaneous phenomenon

Be 3 points with Nausea and vomiting, photophobia, phonophobia etc. 3 or more, 2 is 2 points, and 1 is 1 point.

4, evaluation of clinical curative effect:

Cure: after treatment, headache and simultaneous phenomenon all disappear;

Effective: after treatment, integration reduces more than 50% than integration before treatment;

Effective: after treatment, integration reduces 21% ~ 50% than integration before treatment;

Invalid: after treatment, integration reduces less than 20% than integration before treatment.

5, therapeutic outcome: treatment group, after the treatment of 30 days, cures 20 examples, effective 45 examples, effective 30 examples, invalid 5 examples, total effective rate 95%.

Two, model case:

Example one: Zhang, female, 48 years old, patient had a headache for more than 20 years, often showed effect, and sent out and then had a headache unbearably, with nausea and vomiting.Recently because excessively requiring mental skill, very cold and sending out, begin then blurred vision, photophobia, forehead and eye socket distending pain, continues the then crown and front brow pang unbearably, can not pain relieving with analgesic, and stringy and tense pulse of feeling the pulse, dark tongue quality, the livid purple anger of sublingual vessel is opened.Be diagnosed as migraine, oral medicine of the present invention after 3 days pain alleviate to some extent, after 6 days, pain obviously alleviates, and within 15 days, headache is basic afterwards stops, and following the service is followed up a case by regular visits to do not recur with consolidate curative effect for 15 days half a year.

Example two: gold certain, female, 45 years old, patient had a headache 15 years entirely.Shortly feel headache puerperal, often run into wind and enter in brain with regard to conscious air drill, therefore head wrapped up by whole day towel, especially winter, such as wind and cold was then had a headache as split, and it is invalid to control repeatly.Dimly red tongue, white and thin fur, deep-thready pulse and puckery.Be diagnosed as migraine, oral medicine of the present invention after 2 days conscious headache can tolerate, 6 days afterwards headache obviously alleviate, within 18 days, headache is basic afterwards stops, and following the service is followed up a case by regular visits to do not recur for 1 year with consolidate curative effect for 12 days.

Detailed description of the invention:

Embodiment

Grams takes raw material by weight:

Preparation and instructions of taking: be decocted in water for oral dose, every day potion, sooner or later one after each meal at twice, 30 days is a course for the treatment of, takes a course for the treatment of altogether.

Claims

1. the migrainous Chinese medicine composition of orally taken for curing, is characterized in that being made up of the raw material of Chinese medicine of following parts by weight: Rhizoma Chuanxiong 25, Rhizoma Et Radix Notopterygii 20, Lignum Sappan 15, Fructus Evodiae 15, the Radix Angelicae Dahuricae 9, Herba Asari 5, Rhizoma Ligustici 9, Radix Bupleuri 9, the Radix Paeoniae Alba 12, Radix Glycyrrhizae 10.