CN104666441A - Traditional Chinese medicine composition for treating prostatic hyperplasia and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating prostatic hyperplasia and preparation method of traditional Chinese medicine composition Download PDFInfo
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- CN104666441A CN104666441A CN201510123947.6A CN201510123947A CN104666441A CN 104666441 A CN104666441 A CN 104666441A CN 201510123947 A CN201510123947 A CN 201510123947A CN 104666441 A CN104666441 A CN 104666441A
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Abstract
The invention relates to a preparation method of a traditional Chinese medicine composition for treating prostatic hyperplasia. The method comprises the following steps: A) taking 23 parts by weight of balsam pear, 10 parts by weight of radix notoginseng, 5 parts by weight of buckwheat husk, 5 parts by weight of carambola root, 7 parts by weight of ternate grape fern herb, 15 parts by weight of seabuckthorn, 12 parts by weight of honeycomb, 9 parts by weight of linearstripe rabdosia herb and 6 parts by weight of fructus toosendan, mixing, and crushing; adding 70% ethanol according to the material-liquid ratio of 1: 7, performing reflux extraction three times, 2 hours per time, filtering and merging filtrates; and concentrating into a thick paste with relative density of 1.30-1.35 (20 DEG C); and B) mixing the thick paste in the step A) with 1.1 parts by weight of vitamin B2, then drying at 40-45 DEG C and preparing into powder. The powder is uniformly stirred and then loaded into capsules to prepare capsules. Each capsule contains 0.33g of the traditional Chinese medicine composition. The administration method is as follows: taking 4 capsules respectively in the morning and evening with warm boiled water.
Description
Technical field
The invention belongs to Chinese medicine formula and preparing technical field, be specifically related to a kind of Chinese medicine composition for the treatment of prostate hyperplasia and preparation method thereof.
Background technology
The Symptoms of prostatic hyperplasia is: 1, acraturesis, urine line attenuate and dribbling: cause urine line attenuate because urethra shrivels by hypertrophy prostate, controlled micturition will use larger strength to overcome resistance, along with the development of the state of an illness, also may there is interruption of urinating, the sound of rain pattering symptom such as not to the utmost after urinating., when blocking serious, acute urinary retention can be there is because reason such as urine overlong time or infection etc. of suffering from cold, drink, suppress causes urine to discharge in 2, urine retention: the patients with terminal that prostatic hyperplasia is heavier.3, hematuria: be with blood to be hematuria, also known as hematuria in urine.Under normal circumstances, be not erythrocytic in urine.Medically after patient urine centrifugation, check with microscope, if having the erythrocyte of more than 5 in each high power field, be just hematuria.The treatments such as the multiplex tamsulosin hydrochloride slow releasing capsule of doctor trained in Western medicine, Tamsulosin sheet, traditional Chinese medical science Duo Zhi is with reinforcing the kidney and supporting YANG, clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling etc.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of prostate hyperplasia and preparation method thereof.
The present invention treats the Chinese medicine composition of prostate hyperplasia; Be made up of the raw material of following parts by weight: 20 ~ 25 parts, Fructus Momordicae charantiae, Bulbilus boussingaultiae pseudobaselloidis 9 ~ 11 parts, Testa Fagopyri Esculenti 4 ~ 6 parts, Radix Averrhoae Carambolae 4 ~ 6 parts, raw 6 ~ 8 parts of back of the body Serpentis, Fructus Hippophae 14 ~ 16 parts, 11 ~ 13 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 8 ~ 10 parts, Fructus Toosendan 5 ~ 7 parts, vitamin B2 1 ~ 1.2 part.
As optimization, the Chinese medicine composition of this treatment prostate hyperplasia, is made up of the raw material of following parts by weight: 23 parts, Fructus Momordicae charantiae, Bulbilus boussingaultiae pseudobaselloidis 10 parts, Testa Fagopyri Esculenti 5 parts, Radix Averrhoae Carambolae 5 parts, raw 7 parts of back of the body Serpentis, Fructus Hippophae 15 parts, 12 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 9 parts, Fructus Toosendan 6 parts, vitamin B2 1.1 parts.
Prepare the method for this treatment prostate hyperplasia Chinese medicine composition, comprise the following steps, by weight:
A, get 23 parts, Fructus Momordicae charantiae, Bulbilus boussingaultiae pseudobaselloidis 10 parts, Testa Fagopyri Esculenti 5 parts, Radix Averrhoae Carambolae 5 parts, raw 7 parts of back of the body Serpentis, Fructus Hippophae 15 parts, 12 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 9 parts, Fructus Toosendan 6 parts of co-grindings after; According to solid-liquid ratio 1:7, add 70% ethanol, reflux, extract, 3 times, each 2 hours, filter, merging filtrate; Be condensed into the thick paste that relative density is 1.30 ~ 1.35 (20 DEG C);
B, by thick paste in steps A with 1.1 parts vitamin B2 mixing, then 40 ~ 45 DEG C of oven dry, powder process.By powder, in incapsulating after stirring, make capsule.Every capsules explosive payload 0.33 gram.Instructions of taking is for sooner or later respectively taking 4, and warm water is taken.
In Chinese prescription of the present invention, Fructus Momordicae charantiae has clearing summer heat, improving eyesight removing toxic substances, reducing pressure and sugar, diuresis removing heat from blood, separate that labor clears away heart-fire, effect of QI invigorating tonifying YANG; There is cool, thirst-quenching, heat-clearing and toxic substances removing, the improving eyesight that clears away heart-fire, QI invigorating recover from fatigue, the effect of kidney tonifying diuresis; Containing multivitamin, mineral in Fructus Momordicae charantiae, the magistery containing fat eliminating, fat-reducing, can accelerate toxin expelling.
Bulbilus boussingaultiae pseudobaselloidis liver and kidney tonifying, nourishing, strong waist knee joint, Sweeling-eliminating medicine powder expectorant; Cure mainly waist knee joint arthralgia pain, weak after being ill, traumatic injury, fracture.
Testa Fagopyri Esculenti contains a large amount of rutin glycosides, has the activity of vitamin.Testa Fagopyri Esculenti can prevent the blood capillary fragility hemorrhage of bringing out, especially better with pain, cervical spondylosis, insomniac's effect to migraine, the cool winter in summer is warm, breathe freely calm the nerves, can relieving fatigue.
Radix Averrhoae Carambolae is the root of Oxalidaceae plant Fructus Averrhoae Carambolae, arresting seminal emission, hemostasis, pain relieving; For seminal emission, epistaxis, chronic headache, arthralgia.
The life of back of the body Serpentis has a stomach-ache to treatment, gastric ulcer, renal calculus, fever, enteritis, diarrhea Be very effective; Cure mainly heat-clearing and toxic substances removing, suppressing the hyperactive liver to relieve the wind syndrome, cough-relieving, hemostasis, improving eyesight removing nebula.Little spring flower cures mainly that infantile hyperpyrexia is frightened jerks, cough due to lung-heat, hemoptysis, and pertussis is demented, epilepsy disease, sore swollen toxin, scrofula, venom, conjunctival congestion acute catarrhal conjunctivitis, the raw cataracta of order.
Fructus Hippophae property is sour, puckery, temperature; There is strengthening the spleen to promote digestion, eliminating phlegm and stopping cough, effect of promoting blood circulation to remove blood stasis; Cure mainly in insufficiency of the spleen lack of appetite, abdominal pain due to retention of food, cough with copious phlegm, obstruction of qi in the chest and cardialgia, blood stasis amenorrhea, falls and flutters congestive edema; Can be used for deficiency-weakness of spleen-QI or taste impairment of both QI and YIN, lack of appetite poor appetite, dyspepsia, abdominal distention, fatigue and asthenia person.
Nidus Vespae medical value is very high, the Nidus Vespae treatment rhinitis of conventional fresh clean; New Nidus Vespae also has the curative effect of the diseases such as treatment hepatitis, rhinitis and rheumatic arthritis.Nidus Vespae has the effect promoting Immune Function, Nidus Vespae immersion both had deactivation to hbs antigen, also had very strong restraint to staphylococcus aureus, bacillus pyocyaneus, escherichia coli, dysentery bacterium, Bacillus typhi and proteus vulgaris etc.; Also inhibitory action is had to funguses such as Aspergillus fumigatus, Aspergillus flavus, eggplant sickle bacterium, leukonids.
Herba Rabdosiae Lophanthoidis is traditional herbal medicine, is commonly called as Radix seu caulis Berberidis Gagnepainii (Radix Berberidis Virgetori) etc., has effect of clearing away heat-damp and promoting diuresis, jaundice eliminating damp eliminating, cool the blood dissipate blood stasis, is used for the treatment of the diseases such as acute icterohepatitis, acute cholecystitis, dysentery, enteritis, traumatic injury stasis of blood pain.
Fructus Toosendan is the mature fruit of Fructus Toosendan drying, and brown color has dark point, is a kind of conventional native Sichuan crude drugs, special, and sour in the mouth, hardship are cold in nature; Can be soothing the liver, circulation of qi promoting, pain relieving, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.All medicine compatibilities, play YIN nourishing removing toxic substances, adjusting and reinforcing liver and kidney, promoting blood circulation to remove blood stasis, the effect of clearing away heat-damp and promoting diuresis jointly; The various symptom Be very effective that treatment prostate hyperplasia causes.
Pertinent clinical data is as follows:
Physical data: in 112 routine cases, the oldest 69 years old, minimum 29 years old, equal per anum referred to that the clinical examination diagnosis such as inspection, B ultrasonic are made a definite diagnosis, ultrasound diagnosis: slight loose 49 examples, loose 46 examples of moderate, loose 17 examples of severe.Residual urine <100mL person 51 example, 100 ~ 200mL person 46 example, 201 ~ 250mL person 12 example; Indwelling catheter person 3 example.
Diagnostic criteria: according to " prostatosis Chinese traditional medical diagnose ", symptom: frequent micturition, urinate and wait for and difficulty goes out, weak stream of urine, nocturia, dribble of urine not to the utmost.Rectal tonch: the prostate that can touch hypertrophy, smooth surface, quality is comparatively hard, and disappearence of central groove, has touched tenderness individually.Color ultrasound examination prompting prostate hypertrophy in various degree.
Therapeutic Method: sooner or later respectively take the embodiment of the present invention 1 capsule 4, warm water is taken, and one month is a course for the treatment of.
Efficacy evaluation: " the Chinese medical disease Standardization of diagnosis and curative effect " issued for 1994 with reference to State Administration of Traditional Chinese Medicine is drafted.Effective: urine is unobstructed, clinical symptoms and sign disappear; Take a turn for the better: clinical symptoms and sign are improved; Invalid: clinical symptoms is without improvement.
After case treatment, curative effect statistical result is as follows:
Detailed description of the invention
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.
Embodiment 1:A, get 23 grams, Fructus Momordicae charantiae, after Bulbilus boussingaultiae pseudobaselloidis 10 grams, Testa Fagopyri Esculenti 5 grams, Radix Averrhoae Carambolae 5 parts, raw 7 parts of back of the body Serpentis, Fructus Hippophae 15 parts, 12 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 9 parts, Fructus Toosendan 6 parts pulverize; According to solid-liquid ratio 1:7, add 70% ethanol, reflux, extract, 3 times, each 2 hours, filter, merging filtrate; Be condensed into the thick paste that relative density is 1.30 ~ 1.35 (20 DEG C);
B, by thick paste in steps A with the vitamin B of 1.1 grams
2mixing, then 40 ~ 45 DEG C of oven dry, powder process, after stirring, makes capsule in incapsulating.Every capsules explosive payload 0.33 gram.Instructions of taking is for sooner or later respectively taking 4, and warm water is taken.
Embodiment 2:A, get 20 grams, Fructus Momordicae charantiae, after Bulbilus boussingaultiae pseudobaselloidis 9 grams, Testa Fagopyri Esculenti 4 grams, Radix Averrhoae Carambolae 4 grams, raw 6 grams of back of the body Serpentis, Fructus Hippophae 14 grams, 11 grams, Nidus Vespae, Herba Rabdosiae Lophanthoidis 8 grams, Fructus Toosendan 5 grams pulverize; According to solid-liquid ratio 1:7, add 70% ethanol, reflux, extract, 3 times, each 2 hours, filter, merging filtrate; Be condensed into the thick paste that relative density is 1.30 ~ 1.35 (20 DEG C);
B, by thick paste in steps A with the vitamin B of 1 gram
2mixing, then 40 ~ 45 DEG C of oven dry, powder process, after stirring, makes capsule in incapsulating.Every capsules explosive payload 0.33 gram.Instructions of taking is for sooner or later respectively taking 4, and warm water is taken.
Embodiment 3:A, get 25 grams, Fructus Momordicae charantiae, after Bulbilus boussingaultiae pseudobaselloidis 11 grams, Testa Fagopyri Esculenti 6 grams, Radix Averrhoae Carambolae 6 grams, raw 8 grams of back of the body Serpentis, Fructus Hippophae 16 grams, 13 grams, Nidus Vespae, Herba Rabdosiae Lophanthoidis 10 grams, Fructus Toosendan 7 grams pulverize; According to solid-liquid ratio 1:7, add 70% ethanol, reflux, extract, 3 times, each 2 hours, filter, merging filtrate; Be condensed into the thick paste that relative density is 1.30 ~ 1.35 (20 DEG C);
B, by thick paste in steps A with the vitamin B of 1.2 grams
2mixing, then 40 ~ 45 DEG C of oven dry, powder process, after stirring, makes capsule in incapsulating.Every capsules explosive payload 0.33 gram.Instructions of taking is for sooner or later respectively taking 4, and warm water is taken.
Claims (3)
1. treat the Chinese medicine composition of prostate hyperplasia for one kind; It is characterized in that being made up of the raw material of following parts by weight: 20 ~ 25 parts, Fructus Momordicae charantiae, Bulbilus boussingaultiae pseudobaselloidis 9 ~ 11 parts, Testa Fagopyri Esculenti 4 ~ 6 parts, Radix Averrhoae Carambolae 4 ~ 6 parts, raw 6 ~ 8 parts of back of the body Serpentis, Fructus Hippophae 14 ~ 16 parts, 11 ~ 13 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 8 ~ 10 parts, Fructus Toosendan 5 ~ 7 parts, vitamin B
21 ~ 1.2.
2. Chinese medicine composition according to claim 1, it is characterized in that being made up of the raw material of following parts by weight: 23 parts, Fructus Momordicae charantiae, Bulbilus boussingaultiae pseudobaselloidis 10 parts, Testa Fagopyri Esculenti 5 parts, Radix Averrhoae Carambolae 5 parts, raw 7 parts of back of the body Serpentis, Fructus Hippophae 15 parts, 12 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 9 parts, Fructus Toosendan 6 parts, vitamin B
21.1 part.
3. prepare a method for the treatment of prostate hyperplasia Chinese medicine composition described in claim 2, it is characterized in that comprising the following steps, by weight:
A, get 23 parts, Fructus Momordicae charantiae, after Bulbilus boussingaultiae pseudobaselloidis 10 parts, Testa Fagopyri Esculenti 5 parts, Radix Averrhoae Carambolae 5 parts, raw 7 parts of back of the body Serpentis, Fructus Hippophae 15 parts, 12 parts, Nidus Vespae, Herba Rabdosiae Lophanthoidis 9 parts, Fructus Toosendan 6 parts pulverize; According to solid-liquid ratio 1:7, add 70% ethanol, reflux, extract, 3 times, each 2 hours, filter, merging filtrate; Be condensed into the thick paste that relative density is 1.30 ~ 1.35 (20 DEG C);
B, by thick paste in steps A with the vitamin B of 1.1 parts
2mixing, then 40 ~ 45 DEG C of oven dry, powder process.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961508A (en) * | 2012-12-14 | 2013-03-13 | 山东宏济堂制药集团有限公司 | Traditional Chinese medicine composition used for treating prostatitis and benign prostatic hyperplasia |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961508A (en) * | 2012-12-14 | 2013-03-13 | 山东宏济堂制药集团有限公司 | Traditional Chinese medicine composition used for treating prostatitis and benign prostatic hyperplasia |
Non-Patent Citations (2)
| Title |
|---|
| 李军等: "清热利湿活血化瘀法治疗前列腺增生症36例", 《广西中医药》 * |
| 郑志杰等: "前列腺增生治疗概况", 《甘肃中医》 * |
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