CN104650352A - Poly-hexamethylene biguanide hydrochloride sterilizing and disinfecting agent - Google Patents
Poly-hexamethylene biguanide hydrochloride sterilizing and disinfecting agent Download PDFInfo
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- CN104650352A CN104650352A CN201310587476.5A CN201310587476A CN104650352A CN 104650352 A CN104650352 A CN 104650352A CN 201310587476 A CN201310587476 A CN 201310587476A CN 104650352 A CN104650352 A CN 104650352A
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- hexamethylene
- sterilizing
- ammonium chloride
- water
- disinfection sanitizer
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Abstract
The invention provides a sterilizing and disinfecting agent being composed of: bicyanamide, ammonium chloride, 1,6-diamidohexane, a catalyst and water. The sterilizing and disinfecting agent is prepared through following processes: (1) performing a melt reaction to the bicyanamide and the ammonium chloride at 170-230 DEG C to obtain guanidine hydrochloride; (2) feeding the guanidine hydrochloride and the 1,6-diamidohexane into a reaction kettle according to the ratio of 1:1 and heating the guanidine hydrochloride and the 1,6-diamidohexane until the reactants are completely dissolved and fully mixed; (3) increasing the temperature to 120-200 DEG C with addition of the catalyst and performing a reaction for 2-3 h until no ammonia gas is discharged from the reaction kettle; (4) when the temperature of the reactants is decreased to 80 DEG C, adding a proper amount of water to finish the reaction for obtain an aqueous solution of poly-hexamethylene biguanide hydrochloride. The sterilizing and disinfecting agent can be used in water treatment in the fields of agriculture, leather industry, breeding industry of poultry and livestock, oil extraction and the like.
Description
Technical field
The present invention relates to a kind of sterilant, specifically, be a kind of hexamethylene disinfection sanitizer, belong to sterilizing articles for use field.
Background technology
Existing sterilant, generally there is certain shortcoming in treatment effect, and production cost is also higher.
For improving the sterilization effect of sterilant, containing multiple harmful material in traditional sterilant moiety, threatening human health, and having pollution to environment; The sterilization kind of sterilant traditional is in addition single, and moiety needs number of chemical composition, causes the raising of preparation cost.
It is sick that farm crop are easy to that in the process of growth the bacterium such as verticillium, blight, damping-off occur, these bacterium disease mainly soil infections, soil is once sense these germs upper, farm crop bacterium such as verticillium, blight, damping-off on this grown on soil just will inevitably be felt is sick, in the serious obvious underproduction of plot farm crop, even have no harvest, bring great impact to agriculture production.
At present, the upper this disease of crop growth initial stage sense, the germ killing drugs such as most employing derosal, white powder are peaceful, cotton Feng Bao carry out sprinkling sterilization, but these medicines can only mitigate the disease, can not effect a radical cure, still can infect the bacterium such as verticillium, blight, damping-off this grown on soil next batch of farm crop sick, every batch of farm crop all need to carry out sterilization operation, affect the output of farm crop, add planting cost.
Summary of the invention
The object of the invention is to avoid the deficiencies in the prior art part and provide a kind of efficient, safety, sterilization effect be strong, disinfection effect is strong, excellent property, and use cost is low to the disinfecting sterilizing agent of human body without harm.
For achieving the above object, the technology used in the present invention solution is:
The first step: dicyandiamide and ammonium chloride are carried out frit reaction at 170-230 DEG C, obtains Guanidinium hydrochloride crude product, through refining to obtain finished product.
Second step: Guanidinium hydrochloride fine work obtained in the previous step and 1，6-diaminohexane are put into reactor by 1:1 and is heated with stirring to and dissolves completely and fully mix, be then warming up to 120 ~ 200 DEG C, intensification adds catalyzer.
3rd step: react 2 ~ 3 hours, until reactor ammonia at noon is released, adds suitable quantity of water when question response thing temperature is down to 80 DEG C, and reaction terminates, and obtains the aqueous solution of poly (hexamethylene) hydrochloride.
The present invention adopts technique scheme, have the following advantages: this sterilant, after spraying farm crop, effectively can prevent and treat the bacterium such as verticillium, blight, damping-off sick, make next batch of farm crop no longer by the impact of this bacterium disease, improve the output of farm crop, reduce the planting cost of farm crop.This sterilant moiety is simple, and preparation cost is cheap, to human body and environment without harm, practical.
Broad-spectrum antimicrobial of the present invention, to gram-positive microorganism, Gram-negative bacteria, fungi and yeasts etc. all have killing action.The fields such as daily chemical industry, water treatment, health care can be widely used in.Be usually used in fruits and vegetables, To Disinfection of Aquatic Products agent, the agent of sewage disposal flocculating sterilizing, the products such as crop-dusting sterilant.Compare with polyhexamethylene list guanidine, the fungistatic effect of poly hexamethylene biguanide to millet straw bacillus, saccharomyces cerevisiae and black-koji mould is better than polyhexamethylene list guanidine.Because poly hexamethylene biguanide is high molecular polymer structure, so each bacterioid can not develop immunity to drugs to it, this is confirmed by the experiment of external authoritative feeler mechanism.
Specific embodiment
Clearly understand, below in conjunction with embodiment to make object of the present invention, technical scheme and advantage.
Embodiment 1:
Preparation scheme is: dicyandiamide and ammonium chloride are carried out frit reaction at 170-230 DEG C, obtain Guanidinium hydrochloride, then Guanidinium hydrochloride and 1，6-diaminohexane are put into reactor by 1:1 to be heated with stirring to and to dissolve completely and fully mix, be then warming up to 120 ~ 200 DEG C, intensification adds catalyzer, react 2 ~ 3 hours, until reactor ammonia at noon is released, when question response thing temperature is down to 80 DEG C, add suitable quantity of water, reaction terminates, and obtains the aqueous solution of poly (hexamethylene) hydrochloride.
This sterilant is the transformed lines show of biguanides sterilant popular in the world, belongs to spectrum light efficiency sterilant, soluble in water, non-volatile.
Embodiment 2:
Preparation scheme is the same.
This sterilant is colourless, nontoxic, nothing is difficult to understand, tasteless, belongs to environmentally friendly machine.
Embodiment 3:
Preparation scheme is the same.
This disinfection sanitizer moiety is simple, and preparation cost is cheap, to human body and environment without harm, practical.
This disinfection sanitizer is the transformed lines show of biguanides sterilant popular in the world, belongs to spectrum light efficiency sterilant, soluble in water, non-volatile, and colourless, nontoxic, without difficult to understand, tasteless, belong to environmentally friendly machine.It is as water treatment biocide. and sterilization effect is remarkable, and lastingly long-acting.
This product can be used for the water treatment biocide of the industries such as agricultural, leather industry, livestock breeding industry, oil production.
The present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Claims (5)
1. a hexamethylene disinfection sanitizer, is characterized in that, it is made up of dicyandiamide, ammonium chloride, 1，6-diaminohexane, catalyzer and water.
2. according to claim 1, described hexamethylene disinfection sanitizer, it is characterized in that, its each components in mass portion number ratio is: dicyandiamide 40 ~ 50 parts, ammonium chloride 40 ~ 50 parts, 1，6-diaminohexane 40 ~ 50 parts, catalyzer 0.4 ~ 2.5 part and appropriate water.
3. according to claim 1 and 2, described hexamethylene disinfection sanitizer, it is characterized in that, its preparation method is:
The first step: dicyandiamide and ammonium chloride are carried out frit reaction at 170-230 DEG C, obtains Guanidinium hydrochloride crude product, through refining to obtain finished product.
Second step: Guanidinium hydrochloride fine work obtained in the previous step and 1，6-diaminohexane are put into reactor by 1:1 and is heated with stirring to and dissolves completely and fully mix, be then warming up to 120 ~ 200 DEG C, intensification adds catalyzer.
3rd step: react 2 ~ 3 hours, until reactor ammonia at noon is released, adds suitable quantity of water when question response thing temperature is down to 80 DEG C, and reaction terminates, and obtains the aqueous solution of poly (hexamethylene) hydrochloride.
4., according to claim 3, described hexamethylene disinfection sanitizer, it is characterized in that, obtained aqueous solution is transparent, for faint yellow or colourless.
5. according to claims 1 to 3, described hexamethylene disinfection sanitizer, is characterized in that, described catalyzer is polyoxyethylene glycol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310587476.5A CN104650352A (en) | 2013-11-20 | 2013-11-20 | Poly-hexamethylene biguanide hydrochloride sterilizing and disinfecting agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310587476.5A CN104650352A (en) | 2013-11-20 | 2013-11-20 | Poly-hexamethylene biguanide hydrochloride sterilizing and disinfecting agent |
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| CN104650352A true CN104650352A (en) | 2015-05-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201310587476.5A Pending CN104650352A (en) | 2013-11-20 | 2013-11-20 | Poly-hexamethylene biguanide hydrochloride sterilizing and disinfecting agent |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106832267A (en) * | 2017-01-11 | 2017-06-13 | 北京长江脉医药科技有限责任公司 | A kind of guanidine copolymer and preparation method thereof |
| CN108084434A (en) * | 2017-12-04 | 2018-05-29 | 辽宁科技大学 | A kind of method that polyhexamethylene list guanidine hydrochloride is prepared by spent acid lye |
| CN108935463A (en) * | 2018-08-15 | 2018-12-07 | 新疆水处理工程技术研究中心有限公司 | A kind of oil field reinjection water compound disinfectant and preparation method thereof |
-
2013
- 2013-11-20 CN CN201310587476.5A patent/CN104650352A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106832267A (en) * | 2017-01-11 | 2017-06-13 | 北京长江脉医药科技有限责任公司 | A kind of guanidine copolymer and preparation method thereof |
| CN108084434A (en) * | 2017-12-04 | 2018-05-29 | 辽宁科技大学 | A kind of method that polyhexamethylene list guanidine hydrochloride is prepared by spent acid lye |
| CN108935463A (en) * | 2018-08-15 | 2018-12-07 | 新疆水处理工程技术研究中心有限公司 | A kind of oil field reinjection water compound disinfectant and preparation method thereof |
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150527 |
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| WD01 | Invention patent application deemed withdrawn after publication |