CN104645156A - Formula of drug for treating syphilis and preparation method of drug - Google Patents

Formula of drug for treating syphilis and preparation method of drug Download PDF

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Publication number
CN104645156A
CN104645156A CN201510041702.9A CN201510041702A CN104645156A CN 104645156 A CN104645156 A CN 104645156A CN 201510041702 A CN201510041702 A CN 201510041702A CN 104645156 A CN104645156 A CN 104645156A
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parts
herba
radix
preparation
syphilis
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陶风英
张瑜
王璐
王玲
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Qingdao Municipal Hospital
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Qingdao Municipal Hospital
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Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a formula of a drug for treating syphilis and a preparation method of the drug. The drug comprises benzathine benzylpenicillin and a traditional Chinese medicine composition, wherein the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-10 parts of aerba lupulin, 1-3 parts of brucea javanica, 3-8 parts of spiny green rhizome, 3-5 parts of galeopsis bifida, 3-8 parts of Japanese balanophora herbs, 3-5 parts of redspot swertia herbs, 3-5 parts of riparian homonoia roots, 3-8 parts of honeysuckle flower distillates, 3-5 parts of balsam pear leaves, 3-5 parts of Chinese pulsatilla roots, 3-5 parts of radix sanguisorbae, 3-5 parts of cortex moutan, 3-5 parts of Japanese violet herbs or roots, 1-3 parts of gynura divaricata, 3-8 parts of sophora japinica, 5-8 parts of thyme, 3-8 parts of erigeron breviscapus, 1-3 parts of indigo naturalis, 1-3 parts of glaucescent fissistigma roots and 3-5 parts of houttuynia cordata. Granules are prepared by using the preparation method. The drug is mainly used for assisting benzathine benzylpenicillin in treating, has the auxiliary effects of eliminating evil and strengthening the body resistance, cooling blood to remove pathogenic heat and enhancing the immunity, can be used for replenishing vigor and is rapid in taking effects and favorable in treatment effect.

Description

A kind of pharmaceutical formulation for the treatment of syphilis and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of pharmaceutical formulation for the treatment of syphilis and preparation method thereof.
Background technology
Syphilis is chronic, the systemic sexually transmitted disease (STD) caused by spirochaeta pallida.Mainly through sex track transmission, primary syphilis, secondary syphlilis, tertiary syphilis, latent syphilis and congenital syphilis etc. can be shown as clinically.Be in " People's Republic of China's law on the prevention and control of infectious diseases ", be classified as the disease kind of Class B control stategy.Syphilis is popular in the whole world, estimates according to WHO, and about there are 1,200 ten thousand new cases in the whole world every year, mainly concentrates on South Asia, Southeast Asia and secondary sub-Saharan Africa.Syphilis is at China's rapid development in recent years, has become the sexually transmitted disease (STD) that reported cases number is maximum.In the syphilis reported, latent syphilis occupies the majority, and one, secondary syphlilis is also comparatively common, congenital syphilis reported cases number is also in increase.
Existing Therapeutic Principle emphasizes early diagnosis, early treatment, and the course for the treatment of is regular, and dosage is enough.Regularly carry out clinical and laboratory after treatment to follow up a case by regular visits to.Sexual will rule together with looking into.Early syphilis can clinical recovery through thorough treatment, eliminates infectiousness.Tertiary syphilis's treatment can eliminate inflammation in tissue, but the tissue of destroyed is difficult to repair.Chinese patent (CN101433671) discloses a kind of medicine for the treatment of syphilis, and have with the effect of the cool dehumidifying that purifies the blood, but late period, cure rate was lower, pure Chinese medicine takes effect slowly, possesses certain limitation.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical formulation for the treatment of syphilis, based on the treatment of benzathine benzylpenicillin, auxiliary with the effect of eliminating pathogenic factor for supporting vital QI, removing pathogenic heat from blood and toxic substance from the body, enhancing immunity, supplement vigour, soon effective, there is good therapeutic effect.
The present invention includes benzathine benzylpenicillin injection and Chinese medicine composition with the use of, described Chinese medicine composition is formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5 ~ 10 parts, Fructus Bruceae 1 ~ 3 part, Rhizoma Smilacis ferocis 3 ~ 8 parts, weasel hemp nettle 3 ~ 5 parts, Herba balanophorae japonicae 3 ~ 8 parts, Herba Swertiae erythrostictae 3 ~ 5 parts, Radix Homonoiae Ripariae 3 ~ 5 parts, the Liquor Flos Lonicerae Distillata 3 ~ 8 parts, Folium Momordicae Charantiae 3 ~ 5 parts, the Radix Pulsatillae 3 ~ 5 parts, Radix Sanguisorbae 3 ~ 5 parts, Cortex Moutan 3 ~ 5 parts, Herba Violae japonicae 3 ~ 5 parts, Radix et Rhizoma Gynurae divaricatae 1 ~ 3 part, Japanese pagodatree leaf 3 ~ 8 parts, Herba thymi vulgaris 5 ~ 8 parts, Herba Erigerontis 3 ~ 8 parts, Indigo Naturalis 1 ~ 3 part, Radix Fissistigmatis Glaucescentis 1 ~ 3 part, Herba Houttuyniae 3 ~ 5 parts.
Described Chinese medicine composition is more preferably formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 8 parts, Fructus Bruceae 2 parts, Rhizoma Smilacis ferocis 5 parts, weasel hemp nettle 4 parts, Herba balanophorae japonicae 2 parts, Herba Swertiae erythrostictae 4 parts, Radix Homonoiae Ripariae 4 parts, the Liquor Flos Lonicerae Distillata 5 parts, Folium Momordicae Charantiae 4 parts, the Radix Pulsatillae 4 parts, Radix Sanguisorbae 4 parts, Cortex Moutan 4 parts, Herba Violae japonicae 4 parts, Radix et Rhizoma Gynurae divaricatae 2 parts, Japanese pagodatree leaf 5 parts, Herba thymi vulgaris 6 parts, Herba Erigerontis 5 parts, Indigo Naturalis 2 parts, Radix Fissistigmatis Glaucescentis 2 parts, Herba Houttuyniae 4 parts.
Preparation method chooses each component of Chinese medicine in proportion, grind to form smalls, mix homogeneously, 65% alcohol heating reflux mixture being added 8 times extracts 45 minutes, alcohol heating reflux remainder being added again 6 times 65% extracts 30 minutes, extracted twice liquid filters after merging, and is concentrated into the clear paste that density is 1.50, for subsequent use; Add in clear paste after granule made by dextrin and pack.
Pharmacology analysis:
White luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.): antipyretic antiinflammatory, promoting blood circulation and detumescence.All herbal medicine, cures mainly the cough of consumptive disease wound, haematemesis gas carbuncle, falls the damage stasis of blood and coagulates, facial paralysis, syphilis anthrax.
Fructus Bruceae: bitter in the mouth, cold in nature, slightly poisonous, return large intestine, Liver Channel.There are heat-clearing and toxic substances removing, effect such as corrosion wart, dysentery relieving preventing the attack (or recurrence) of malaria etc.Cure mainly wart wart, tumor, clavus, malaria, dysentery etc." Records of Tradition Chinese and Western Medicine in Combination Fructus Bruceae solution " is stated: " mash vinegar and dress furunculosis.Be apt to control wart." modern pharmacological research display, Fructus Bruceae has the effects such as antitumor, malaria, parasiticide.
Rhizoma Smilacis ferocis: effect expelling wind and removing dampness, separates sore; Dispelling the wind and dampness pathogens bones and muscles pain, stranguria with turbid discharge, syphilis, ecthyma, skin allergy, eczema.
Weasel hemp nettle: sweet in the mouth, micro-hardship, cold nature.Function heat-clearing and toxic substances removing, improving acuity of vision and removing nebula; Cure mainly conjunctival congestion and swelling pain, cataracta, syphilis, skin infection.
Herba balanophorae japonicae: bitter sweet, cool.Effect heat clearing away, removing toxic substances, relieving alcoholic intoxication; Control wind heat skin eruption, cough due to lung-heat spits blood, metrorrhagia, hemorrhoid.
Herba Swertiae erythrostictae: bitter, cool.Enter the heart, lung, spleen channel; Cure mainly that pneumonia, jaundice, syphilis, skin ulcer are swollen, pharyngeal swelling, scabies.
Radix Homonoiae Ripariae: bitter, cold." register planted by Guangxi medicine ": " diuresis.Control traumatic injury, ulcer, hemorrhoid, gonorrhea, syphilis, vesical calculus, cholelithiasis.”
The Liquor Flos Lonicerae Distillata: be the distillate of caprifoliaceae plant In Flower Buds of Lonicera Japonica Thunb (Flos Lonicerae)." Chinese medicine voluminous dictionary ": " nourish blood, quench the thirst.Control warm acute diseases such as cholera and sunstroke pox, carbuncle, syphilis, dysentery.”
Folium Momordicae Charantiae: bitter in the mouth, cool in nature.Function heat-clearing and toxic substances removing; Cure mainly sore and toxic, syphilis, dysentery.
The Radix Pulsatillae: bitter in the mouth, cold in nature; Return stomach warp, large intestine channel.There is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, effect of removing dampness and killing parasites; Cure mainly pyretic toxicity dysentery, epistaxis, internal hemorrhoid with bleeding, leukorrhagia, pudendal pruritus, carbuncle skin ulcer, scrofula.
Radix Sanguisorbae: cold in nature, bitter in the mouth acid, nontoxic; Return liver, lung, kidney and large intestine channel.There is cooling blood for hemostasis, heat-clearing and toxic substances removing, train clear yin nourishing, the effects such as detumescence sore.
Cortex Moutan: cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN; Liver; Kidney; Lung meridian.Effect clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury, beriberoid pyretic arthralgia.
Herba Violae japonicae: taste bitter, acrid, cold.GUIXIN, lung meridian.Have heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Radix et Rhizoma Gynurae divaricatae: acrid in the mouth, light, property is put down.Effect blood sugar lowering, clearing away heat and cooling blood, promoting blood circulation and stopping pain, hemostasis; For cough, bronchitis, pulmonary tuberculosis, skin infection, carbuncle, scalds, traumatic injury, rheumatalgia, metrorrhagia, traumatic hemorrhage.Relaxing muscles and tendons, blood stasis dispelling.Control pertussis, fracture, wound hemorrhage, carbuncle furuncle.
Japanese pagodatree leaf: bitter is flat, nontoxic.Cure mainly infantile convulsion, high fever, hemorrhoidal hamorrhage, hematuria, hemorrhoid, scabies, eczema, furuncle swells.
Herba thymi vulgaris: improve digestive system and gynaecopathia, blood circulation promoting, enhancing immunity, alleviate neuropathic pain, antibacterial.Help wound healing, treatment eczema and pimples skin quality.Activating brain cell, promotes memory and attention, resists dejected and consoles emotional trauma.Dandruff and suppression are shaved one's head very effective.Antibacterial, spasmolytic, anti-insecticide venom, sterilize, keep fit, shortly to scab.
Herba Erigerontis: energy dredge the meridian passage and blood circulation promoting and blood stasis dispelling, expansion of cerebral vascular, reduction vascular resistance, improve cerebral circulation, increase heart and brain blood flow, improve immunologic function, cold in nature, micro-hardship, Gan Wenxin, have effect of be slightly cold removing toxic substances, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, dredge the meridian passage, anti-inflammatory analgetic.
Indigo Naturalis: nature and flavor are salty-cold, returns liver, lung, stomach warp.There are the effects such as heat-clearing and toxic substances removing, removing heat from blood are loose swollen, purging liver-fire, arresting convulsion.Cure mainly epidemic febrile disease intenseness of heat, macule, spit blood, spitting of blood, pharyngalgia, aphtha, pediatric epilepsy scared, skin ulcer swells, erysipelas, eczema, Cuo carbuncle, mumps, snake bite and insect sting etc.The effects such as modern pharmacological research shows, and Indigo Naturalis has antitumor, antibacterium and dermatophytes, enhancing immunity, treatment ulcer, protect the liver.
Radix Fissistigmatis Glaucescentis: taste is micro-pungent, puckery, warm in nature; Return Liver Channel.Effect wind-damp dispelling, restores menstrual flow and invigorates blood circulation, hemostasis; For rheumatic arthralgia, menoxenia, traumatic injury, fracture, traumatic hemorrhage.
Herba Houttuyniae: acrid in the mouth, cold, return lung meridian.Heat-clearing and toxic substances removing, detumescence can treat skin ulcer, promoting urination to remove dampness, clearing away heat to cure dysentery, invigorating the stomach and promoting digestion, by the lung abscess, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc. of controlling excess-heat, pyretic toxicity, damp, disease heat are trouble.Modern pharmacology experiment shows, this product has the effect such as antibacterial, antiviral, raising immunity of organisms, diuresis.
The present invention is based on the treatment of benzathine benzylpenicillin, auxiliary with the effect of eliminating pathogenic factor for supporting vital QI, removing pathogenic heat from blood and toxic substance from the body, enhancing immunity, supplements vigour, soon effective, has good therapeutic effect.
Outcome measure:
Effective: syphilis is fully recovered, body constitution recovers normal, observes 1 year without recidivist;
Take a turn for the better: the state of an illness is clearly better, and body constitution is progressively recovered;
Invalid: all diseases are without improvement.
Therapeutic outcome: treatment patient 104 example, uses medicine of the present invention, and injection benzathine benzylpenicillin, add appropriate sterilized water for injection before use and make into suspension, 600,000 ~ 1,200,000 U/ time, 3 weeks 1 time, once-a-day, a 50g 3 weeks is a course for the treatment of to Chinese medicinal granule.After treating 1 course for the treatment of, recovery from illness 75 example, accounts for 72.1%; Take a turn for the better 28 examples, accounts for 26.9%; Invalid 1 example, accounts for 1.0%.
Attached several routine case is described further:
Case 1: king so-and-so, female, 28 years old.Because syphilis first phase is gone to a doctor, the place such as labia clitoris, cervix uteri, anus sized by display erosion location, skin damage is circular boundary ulcer clearly, exceeds surface, and skin ulcer face is more clean, and skin wound has a small amount of purulent secretion, the hardness touched with tweezers.Patient's private prosecution morbidity, to there being symptom to have about one week, without lymph enlargement, but has weak symptom, with upper respiratory tract infection, ulcer surface has greatly unitary coin-size, has 8 places, has pain so that evening to fall asleep, then adopt formula of the present invention to treat, within 3 weeks, namely take a turn for the better, namely 2 courses for the treatment of fully recover.
Case 2: Liu so-and-so, man, 37 years old.Because right shoulder tuberosity is gone to a doctor January.There is a red little pimple without obvious inducement in right shoulder before January in patient, without significant discomfort, does not give treatment, afterwards cumulative large the and slight pruritus of c in the form of a ring of erythra.According to pathological examination results prompting, row syphilis serum test: TRUST (1: 64), TPPA (+); An anti-HI V detects: negative.Clinical diagnosis is secondary syphlilis.Then formula of the present invention is adopted to treat, recovery from illness in 3 weeks.
Detailed description of the invention
Embodiment 1:
A kind of pharmaceutical formulation for the treatment of syphilis, comprise benzathine benzylpenicillin injection and Chinese medicine composition, described Chinese medicine composition is formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 8 parts, Fructus Bruceae 2 parts, Rhizoma Smilacis ferocis 5 parts, weasel hemp nettle 4 parts, Herba balanophorae japonicae 2 parts, Herba Swertiae erythrostictae 4 parts, Radix Homonoiae Ripariae 4 parts, the Liquor Flos Lonicerae Distillata 5 parts, Folium Momordicae Charantiae 4 parts, the Radix Pulsatillae 4 parts, Radix Sanguisorbae 4 parts, Cortex Moutan 4 parts, Herba Violae japonicae 4 parts, Radix et Rhizoma Gynurae divaricatae 2 parts, Japanese pagodatree leaf 5 parts, Herba thymi vulgaris 6 parts, Herba Erigerontis 5 parts, Indigo Naturalis 2 parts, Radix Fissistigmatis Glaucescentis 2 parts, Herba Houttuyniae 4 parts.
Preparation method chooses each component of Chinese medicine except benzathine benzylpenicillin in proportion, grind to form smalls, mix homogeneously, 65% alcohol heating reflux mixture being added 8 times extracts 45 minutes, alcohol heating reflux remainder being added again 6 times 65% extracts 30 minutes, extracted twice liquid filters after merging, and is concentrated into the clear paste that density is 1.50, for subsequent use; Add in clear paste after granule made by dextrin and pack.
Embodiment 2:
A kind of pharmaceutical formulation for the treatment of syphilis, comprise benzathine benzylpenicillin injection and Chinese medicine composition, described Chinese medicine composition is formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 10 parts, Fructus Bruceae 1 part, Rhizoma Smilacis ferocis 8 parts, weasel hemp nettle 3 parts, Herba balanophorae japonicae 8 parts, Herba Swertiae erythrostictae 3 parts, Radix Homonoiae Ripariae 5 parts, the Liquor Flos Lonicerae Distillata 3 parts, Folium Momordicae Charantiae 5 parts, the Radix Pulsatillae 3 parts, Radix Sanguisorbae 5 parts, Cortex Moutan 3 parts, Herba Violae japonicae 5 parts, Radix et Rhizoma Gynurae divaricatae 1 part, Japanese pagodatree leaf 8 parts, Herba thymi vulgaris 5 parts, Herba Erigerontis 8 parts, Indigo Naturalis 1 part, Radix Fissistigmatis Glaucescentis 3 parts, Herba Houttuyniae 3 parts.
Preparation method chooses each component of Chinese medicine except benzathine benzylpenicillin in proportion, grind to form smalls, mix homogeneously, 65% alcohol heating reflux mixture being added 8 times extracts 45 minutes, alcohol heating reflux remainder being added again 6 times 65% extracts 30 minutes, extracted twice liquid filters after merging, and is concentrated into the clear paste that density is 1.50, for subsequent use; Add in clear paste after granule made by dextrin and pack.
Embodiment 3:
A kind of pharmaceutical formulation for the treatment of syphilis, comprise benzathine benzylpenicillin injection and Chinese medicine composition, described Chinese medicine composition is formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5 parts, Fructus Bruceae 3 parts, Rhizoma Smilacis ferocis 3 parts, weasel hemp nettle 5 parts, Herba balanophorae japonicae 3 parts, Herba Swertiae erythrostictae 5 parts, Radix Homonoiae Ripariae 3 parts, the Liquor Flos Lonicerae Distillata 8 parts, Folium Momordicae Charantiae 3 parts, the Radix Pulsatillae 5 parts, Radix Sanguisorbae 3 parts, Cortex Moutan 5 parts, Herba Violae japonicae 3 parts, Radix et Rhizoma Gynurae divaricatae 3 parts, Japanese pagodatree leaf 3 parts, Herba thymi vulgaris 8 parts, Herba Erigerontis 3 parts, Indigo Naturalis 3 parts, Radix Fissistigmatis Glaucescentis 1 part, Herba Houttuyniae 5 parts.
Preparation method chooses each component of Chinese medicine except benzathine benzylpenicillin in proportion, grind to form smalls, mix homogeneously, 65% alcohol heating reflux mixture being added 8 times extracts 45 minutes, alcohol heating reflux remainder being added again 6 times 65% extracts 30 minutes, extracted twice liquid filters after merging, and is concentrated into the clear paste that density is 1.50, for subsequent use; Add in clear paste after granule made by dextrin and pack.

Claims (3)

1. pharmaceutical formulation for the treatment of syphilis and preparation method thereof, it is characterized in that Chinese medicine composition is formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5 ~ 10 parts, Fructus Bruceae 1 ~ 3 part, Rhizoma Smilacis ferocis 3 ~ 8 parts, weasel hemp nettle 3 ~ 5 parts, Herba balanophorae japonicae 3 ~ 8 parts, Herba Swertiae erythrostictae 3 ~ 5 parts, Radix Homonoiae Ripariae 3 ~ 5 parts, the Liquor Flos Lonicerae Distillata 3 ~ 8 parts, Folium Momordicae Charantiae 3 ~ 5 parts, the Radix Pulsatillae 3 ~ 5 parts, Radix Sanguisorbae 3 ~ 5 parts, Cortex Moutan 3 ~ 5 parts, Herba Violae japonicae 3 ~ 5 parts, Radix et Rhizoma Gynurae divaricatae 1 ~ 3 part, Japanese pagodatree leaf 3 ~ 8 parts, Herba thymi vulgaris 5 ~ 8 parts, Herba Erigerontis 3 ~ 8 parts, Indigo Naturalis 1 ~ 3 part, Radix Fissistigmatis Glaucescentis 1 ~ 3 part, Herba Houttuyniae 3 ~ 5 parts.
2. a kind of pharmaceutical formulation for the treatment of syphilis and preparation method thereof as claimed in claim 1, is characterized in that described Chinese medicine composition is formed by the preparation of raw material of following parts by weight: white luxuriant Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 8 parts, Fructus Bruceae 2 parts, Rhizoma Smilacis ferocis 5 parts, weasel hemp nettle 4 parts, Herba balanophorae japonicae 2 parts, Herba Swertiae erythrostictae 4 parts, Radix Homonoiae Ripariae 4 parts, the Liquor Flos Lonicerae Distillata 5 parts, Folium Momordicae Charantiae 4 parts, the Radix Pulsatillae 4 parts, Radix Sanguisorbae 4 parts, Cortex Moutan 4 parts, Herba Violae japonicae 4 parts, Radix et Rhizoma Gynurae divaricatae 2 parts, Japanese pagodatree leaf 5 parts, Herba thymi vulgaris 6 parts, Herba Erigerontis 5 parts, Indigo Naturalis 2 parts, Radix Fissistigmatis Glaucescentis 2 parts, Herba Houttuyniae 4 parts.
3. preparation a kind of pharmaceutical formulation for the treatment of syphilis and preparation method thereof as claimed in claim 1, it is characterized in that being made up of following steps: choose each component of Chinese medicine in proportion, grind to form smalls, mix homogeneously, 65% alcohol heating reflux mixture being added 8 times extracts 45 minutes, and alcohol heating reflux remainder being added again 6 times 65% extracts 30 minutes, filters after extracted twice liquid merges, be concentrated into the clear paste that density is 1.50, for subsequent use; Add in clear paste after granule made by dextrin and pack.
CN201510041702.9A 2015-01-27 2015-01-27 Formula of drug for treating syphilis and preparation method of drug Pending CN104645156A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770653A (en) * 2016-04-23 2016-07-20 包晓娜 Traditional Chinese medicine composition for treating syphilis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1111139A (en) * 1994-06-30 1995-11-08 谢乃抱 Chinese drug for curing venereal disease
CN1650940A (en) * 2004-07-05 2005-08-10 张国印 Chinese herbal medicine for treating cypridopathy, avariosis, aids and virus infection SARS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1111139A (en) * 1994-06-30 1995-11-08 谢乃抱 Chinese drug for curing venereal disease
CN1650940A (en) * 2004-07-05 2005-08-10 张国印 Chinese herbal medicine for treating cypridopathy, avariosis, aids and virus infection SARS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105770653A (en) * 2016-04-23 2016-07-20 包晓娜 Traditional Chinese medicine composition for treating syphilis

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