CN104645118B - A kind of composition of anti-angiocardiopathy - Google Patents
A kind of composition of anti-angiocardiopathy Download PDFInfo
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- CN104645118B CN104645118B CN201510109824.7A CN201510109824A CN104645118B CN 104645118 B CN104645118 B CN 104645118B CN 201510109824 A CN201510109824 A CN 201510109824A CN 104645118 B CN104645118 B CN 104645118B
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- juice
- peanut
- red sorghum
- slurries
- round onions
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- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 69
- 235000017060 Arachis glabrata Nutrition 0.000 claims abstract description 36
- 244000105624 Arachis hypogaea Species 0.000 claims abstract description 36
- 235000010777 Arachis hypogaea Nutrition 0.000 claims abstract description 36
- 235000018262 Arachis monticola Nutrition 0.000 claims abstract description 36
- 235000020232 peanut Nutrition 0.000 claims abstract description 36
- 240000006394 Sorghum bicolor Species 0.000 claims abstract description 29
- 235000011684 Sorghum saccharatum Nutrition 0.000 claims abstract description 29
- 235000002732 Allium cepa var. cepa Nutrition 0.000 claims abstract description 27
- 235000004347 Perilla Nutrition 0.000 claims abstract description 26
- 238000003756 stirring Methods 0.000 claims abstract description 13
- 238000002360 preparation method Methods 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000000227 grinding Methods 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 34
- 241000234282 Allium Species 0.000 claims description 25
- 241000229722 Perilla <angiosperm> Species 0.000 claims description 24
- 239000002002 slurry Substances 0.000 claims description 21
- 239000012153 distilled water Substances 0.000 claims description 18
- 239000007787 solid Substances 0.000 claims description 9
- 238000007654 immersion Methods 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 3
- 230000035784 germination Effects 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 2
- 238000010025 steaming Methods 0.000 claims 2
- 239000007788 liquid Substances 0.000 abstract description 11
- 239000002775 capsule Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 239000003814 drug Substances 0.000 abstract description 5
- 230000035622 drinking Effects 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 4
- 230000002526 effect on cardiovascular system Effects 0.000 abstract description 3
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 230000032683 aging Effects 0.000 abstract description 2
- 235000008216 herbs Nutrition 0.000 abstract description 2
- 235000012907 honey Nutrition 0.000 abstract description 2
- 230000010354 integration Effects 0.000 abstract description 2
- 230000008092 positive effect Effects 0.000 abstract description 2
- 230000002265 prevention Effects 0.000 abstract description 2
- 244000291564 Allium cepa Species 0.000 abstract 2
- 244000124853 Perilla frutescens Species 0.000 abstract 2
- 238000013019 agitation Methods 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 6
- 239000000843 powder Substances 0.000 description 3
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000001694 spray drying Methods 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010022489 Insulin Resistance Diseases 0.000 description 1
- 235000007199 Panicum miliaceum Nutrition 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 244000022185 broomcorn panic Species 0.000 description 1
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- 206010012601 diabetes mellitus Diseases 0.000 description 1
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- 208000031169 hemorrhagic disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
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- 230000000302 ischemic effect Effects 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
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- 239000011573 trace mineral Substances 0.000 description 1
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- 150000003722 vitamin derivatives Chemical class 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention belongs to field of medicine preparing technology, is related to a kind of composition of anti-angiocardiopathy；Its raw material includes Ji Me Lao Jiu, purple perilla juice, round onions juice, peanut coat juice and red sorghum shell juice, the cleaning of fresh perilla leaf, round onions, peanut and red sorghum, agitation grinding are uniformly mixed stirring into juice addition Ji Me Lao Jiu respectively and are prepared into oral liquid, electuary or capsule, prevention and treatment for angiocardiopathy, to Adult Groups cardiovascular health-care function, prevent aging, softening vessel effect is notable, the adult of 20-40 years old drinks 500-800ml daily, divide three times to divide equally in the morning, afternoon and evening and drink, with age；Consumption temperature is 40-50 DEG C, can add the honey of percentage by weight of the amount of drinking 5% with drink；It prevents and treats positive effect, has no toxic side effect to human body, is formed using integration of drinking and medicinal herbs product mix, and preparation process is simple, and processing cost is low, makes raw material and is easy to get, application environment is friendly.
Description
Technical field：
The invention belongs to field of medicine preparing technology, is related to one kind using the homologous food of natural medicine-food and adds Ji Me Lao Jiu
The composition of anti-angiocardiopathy is prepared into, particularly a kind of composition of the anti-angiocardiopathy of oral formula.
Background technology：
Cardiovascular disease refer to heart caused by hyperlipidemia, blood viscousness, atherosclerosis, hypertension etc.,
Ischemic or hemorrhagic disease occur for brain and body tissue, are a kind of common diseases of serious threat human health, the annual winter
Season is the high-incidence season of cardiovascular disease, and winter temperature gradually reduces, is dry, day and night temperature ambassador human vas is shunk, and easily leads
Blood circulation is caused to be obstructed, angiemphraxis, so as to induce the breaking-out and recurrence of cardiovascular disease, such as myocardial infarction, more extreme consequence
It can cause to die suddenly.At present, the treatment of most of angiocardiopathies generally with reduce sympathetic activity, improve insulin resistance,
Adjust blood fat, antiplatelet and anticoagulant to be treated, taking substantial amounts of medicine daily has body certain injury, seriously
Patient need to do stent procedure.In the prior art, scientific research personnel constantly develops and updates the medicine and device for the treatment of cardiovascular disease
Tool, as Chinese patent 00112326.2 discloses a kind of pharmaceutical composition for treating cardiovascular disease；Chinese patent 02133850.7
Disclose a kind of diabetes, cardiovascular disease therapies machine etc.；Ji Me Lao Jiu is one of Chinese classical famous brand of wine, it contains 16 kinds of human body institutes
The trace element and enzyme vitamin needed, 17 kinds of amino acid, human metabolism can be promoted by usually drinking, and be built up health, and be prevented
Disease, promotes longevity, and is the efficacy-enhancing ingredient of plurality of Chinese；The natural food science of Ji Me Lao Jiu and a variety of integration of drinking and medicinal herbs is prepared,
For preventing and treating angiocardiopathy, have no toxic side effect to human body, this technology is so far there is not yet pertinent literature is reported.
The content of the invention：
It is an object of the invention to overcome shortcoming existing in the prior art, seek design one kind and purple is added in Ji Me Lao Jiu
Soviet Union's juice, round onions juice, peanut coat juice and red sorghum shell juice are prepared by mixing into the oral liquid composition of prevention and treatment angiocardiopathy.
To achieve these goals, in the composition of the present invention for anti-angiocardiopathy each raw material composition weight
Measuring proportioning is：20~30 parts of Ji Me Lao Jiu, 10~20 parts of purple perilla juice, 10~15 parts of round onions juice, 5~10 parts of peanut coat juice and red height
5~10 parts of fine strain of millet shell juice.
The preparation method of the composition of anti-angiocardiopathy of the present invention includes the preparation of purple perilla juice, prepared by round onions juice,
Prepared by peanut coat juice, red sorghum shell juice prepares and five steps of composition finished product：
(1) prepared by purple perilla juice：Choose and grow the fresh perilla leaf of 30~50 days, first rinsed well with clear water, then it is cut into 1~
The bulk of 2cm, is then placed in mixer and adds distilled water, its perilla leaf：The weight ratio of distilled water is 1:1, stir into purple
Fixture residue is filtered out after perilla leaf slurries and obtains purple perilla juice；
(2) prepared by round onions juice：The bulk of 3~5cm will be cut into without rotten red skin round onions, be then placed in mixer and adds
Enter distilled water, round onions：The weight ratio of distilled water is 2:1, round onions slurries are stirred into, round onions juice is obtained after filtering solid residue；
(3) prepared by peanut coat juice：The completely peanut kernels without germination are chosen, after being rinsed with clear water, is put into pure water and controls
When 10~15 DEG C of immersions 8~12 of temperature are small, the weight ratio of peanut kernels and pure water is 1:2~3, after immersion, by peanut coat
Peel off, take out peanut kernels of having no clothes, then peanut coat and soak are all poured into grind in mixer and are beaten, then by peanut coat
Slurries are heated up to 60~80 DEG C of stirrings 5~slurries are filtered out solid residue after ten minutes obtain peanut coat juice；
(4) preparation of red sorghum shell juice：Red sorghum shell is chosen, is first rinsed well with clear water, places into mixer and adds
Enter distilled water, red sorghum shell：The weight ratio of distilled water is 1:3, grinding stirs into red sorghum shell slurries, and red sorghum shell slurries are added
Warm to 80~90 DEG C are stirred 10~15 minutes, and slurries are filtered out solid residue after cooling and obtain red sorghum shell juice；
(5) composition finished product：It is 10~20 parts of purple perilla juice by weight ratio by each component prepared by step (1)~(4),
20~30 parts of 10~15 parts of round onions juice, 5~10 parts of peanut coat juice, 5~10 parts of red sorghum shell juice and Ji Me Lao Jiu, are put into agitator tank
Composition oral liquid is stirred 5~10 minutes to obtain under the conditions of interior 20~30 DEG C of temperature control；Or the composition mouth that will further stir evenly
Take liquid and composition powder electuary is prepared into by spray drying, be reloaded into capsule softgel shell and obtain composition capsule.
Ji Me Lao Jiu used in the present invention is that Shandong Jimo Rice Winery produces by raw material of milled glutinous broomcorn millet；Stirring and granulation used are set
Standby is commercially available conventional equipment；Prepared composition has three kinds of oral liquid, powder electuary and capsule forms.
Compared with prior art, the present invention it prevents and treats positive effect, have no toxic side effect, eaten using medicine same to human body
Product-derived mixes, and preparation process is simple, and processing cost is low, makes raw material and is easy to get, application environment is friendly.
Embodiment：
Further description is made to the present invention with reference to specific embodiment.
Embodiment 1：
The preparation method for the composition for anti-angiocardiopathy that the present embodiment is related to includes the preparation of purple perilla juice, round onions juice
Prepare, prepared by peanut coat juice, red sorghum shell juice prepares and five steps of composition finished product：
(1) prepared by purple perilla juice：Choose and grow the fresh perilla leaf of 30~50 days, first rinsed well with clear water, then it is cut into 1~
The bulk of 2cm, is then placed in mixer and adds distilled water, its perilla leaf：The weight ratio of distilled water is 1:1, stir into purple
Perilla leaf slurries, finally filter out fixture residue and obtain purple perilla juice；
(2) prepared by round onions juice：The bulk of 3~5cm will be cut into without rotten red skin round onions, be then placed in mixer and adds
Enter distilled water, round onions：The weight ratio of distilled water is 2:1, round onions slurries are stirred into, then slurries are filtered out into solid residue and obtain round onions
Juice；
(3) prepared by peanut coat juice：The completely peanut kernels without germination are chosen, after being rinsed with clear water, is put into pure water and controls
When 10~15 DEG C of immersions 8~12 of temperature are small, the weight ratio of peanut and pure water is 1:2~3, after being soaked, peanut coat is shelled
From, peanut kernels of having no clothes are taken out, then peanut coat and the water that is soaked all are poured into grind in mixer and are beaten, then peanut coat is starched
Liquid is heated up to 60~80 DEG C and stirs 5~10 minutes, and slurries finally are filtered out solid residue and obtain peanut coat juice；
(4) preparation of red sorghum shell juice：Red sorghum shell is chosen, is first rinsed well with clear water, places into mixer and adds
Enter distilled water, red sorghum shell：The weight ratio of distilled water is 1:3, grinding stirs into red sorghum shell slurries, and red sorghum shell slurries are added
Warm to 80~90 DEG C are stirred 10~15 minutes, and slurries are filtered out solid residue after cooling and obtain red sorghum shell juice；
(5) composition finished product：It is 15 parts of purple perilla juice by weight ratio by each component prepared by step (1)~(4), round onions
25 parts of 13 parts of juice, 13 parts of peanut coat juice, 7 parts of red sorghum shell juice and Ji Me Lao Jiu, are put into 20~30 DEG C of conditions of temperature control in agitator tank
Lower stirring obtains composition oral liquid in 5~10 minutes；Or further the composition oral liquid stirred evenly is made by being spray-dried
For into composition powder electuary, it is reloaded into capsule softgel shell and obtains composition capsule.
Oral liquid manufactured in the present embodiment should be drunk when taking at 30~60 minutes before meals, and the adult of 20~40 years old drinks daily
With 500~800ml, divide three times to divide equally in the morning, afternoon and evening and drink, with age；Consumption temperature is 40~50 DEG C, can add drink
The honey of the percentage by weight of dosage 5% is the same as drink；The present embodiment by 3 years to three groups totally 150 people different age group crowd drink
With, it was demonstrated that it is obvious to cardiovascular health-care function effect, wherein 58% crowd is evident in efficacy, 32% crowd's curative effect is obvious,
10% crowd's vascular function has improvement.
Embodiment 2：
In the composition for the anti-angiocardiopathy that the present embodiment is related to, each raw material presses 20 parts of Ji Me Lao Jiu, 20 parts of purple perilla juice,
10 parts of round onions juice, 10 parts of peanut coat juice, the part by weight of 10 parts of red sorghum shell juice are mixed evenly, composition oral of bottling to obtain
Liquid finished product；With embodiment 1, obtained finished product can be used for, to Adult Groups cardiovascular health-care function, preventing aging its preparation process, soft
It is notable to change vascular effects.
Embodiment 3：
The composition for the anti-angiocardiopathy that the present embodiment is related to, wherein each raw material presses 20 parts of Ji Me Lao Jiu, purple perilla juice 10
Part, 15 parts of round onions juice, 10 parts of peanut coat juice, the part by weight of 5 parts of red sorghum shell juice are mixed evenly, composition mouth of bottling to obtain
Take liquid finished product；Or powdering further is dried with spray drying device, obtain composition electuary finished product with vacuum bag airtight package；
Its preparation process takes with embodiment 1, finished product with 1 equivalent of embodiment.
Claims (1)
1. a kind of composition of anti-angiocardiopathy, it is characterised in that each raw material is Ji Me Lao Jiu, purple perilla juice, round onions juice, peanut
Clothing juice and red sorghum shell juice；Its preparation process is：
(1) prepared by purple perilla juice：The fresh perilla leaf of growth 30~50 days is chosen, is first rinsed well with clear water, then be cut into 1~2cm
Bulk, be then placed in mixer and add distilled water, its perilla leaf：The weight ratio of distilled water is 1:1, stir into perilla leaf
Fixture residue is filtered out after slurries and obtains purple perilla juice；
(2) prepared by round onions juice：The bulk of 3~5cm will be cut into without rotten red skin round onions, be then placed in mixer and adds steaming
Distilled water, round onions：The weight ratio of distilled water is 2:1, round onions slurries are stirred into, round onions juice is obtained after filtering solid residue；
(3) prepared by peanut coat juice：The completely peanut kernels without germination are chosen, after being rinsed with clear water, are put into temperature control 10 in pure water
When immersion 8~12 is small under the conditions of~15 DEG C, the weight ratio of peanut kernels and pure water is 1:2~3, after immersion, by peanut
Clothing is peeled off, and takes out peanut kernels of having no clothes, then peanut coat and soak are all poured into grind in mixer and are beaten, then by peanut
Clothing slurries are heated up to 60~80 DEG C of stirrings 5~slurries are filtered out solid residue after ten minutes obtain peanut coat juice；
(4) preparation of red sorghum shell juice：Red sorghum shell is chosen, is first rinsed well with clear water, places into mixer and adds steaming
Distilled water, red sorghum shell：The weight ratio of distilled water is 1:3, grinding stirs into red sorghum shell slurries, and red sorghum shell slurries are heated up to
80~90 DEG C are stirred 10~15 minutes, and slurries are filtered out solid residue after cooling and obtain red sorghum shell juice；
(5) composition finished product：It is 15 parts of purple perilla juice by weight ratio by each component prepared by step (1)~(4), round onions juice 13
25 parts of part, 13 parts of peanut coat juice, 7 parts of red sorghum shell juice and Ji Me Lao Jiu, are put into agitator tank and are stirred under the conditions of 20~30 DEG C of temperature control
Mix 5~10 minutes to obtain composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510109824.7A CN104645118B (en) | 2015-03-13 | 2015-03-13 | A kind of composition of anti-angiocardiopathy |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510109824.7A CN104645118B (en) | 2015-03-13 | 2015-03-13 | A kind of composition of anti-angiocardiopathy |
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| Publication Number | Publication Date |
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| CN104645118A CN104645118A (en) | 2015-05-27 |
| CN104645118B true CN104645118B (en) | 2018-04-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510109824.7A Expired - Fee Related CN104645118B (en) | 2015-03-13 | 2015-03-13 | A kind of composition of anti-angiocardiopathy |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1981848A (en) * | 2006-01-20 | 2007-06-20 | 李甲怀 | Extraction and use for cold-pressed concentrate composition of celery, Chinese onion and onion |
| CN103040063A (en) * | 2012-12-31 | 2013-04-17 | 吐鲁番金澳果业有限公司 | Red date and peanut coat compound beverage and preparation method thereof |
-
2015
- 2015-03-13 CN CN201510109824.7A patent/CN104645118B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1981848A (en) * | 2006-01-20 | 2007-06-20 | 李甲怀 | Extraction and use for cold-pressed concentrate composition of celery, Chinese onion and onion |
| CN103040063A (en) * | 2012-12-31 | 2013-04-17 | 吐鲁番金澳果业有限公司 | Red date and peanut coat compound beverage and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 冠心病患者饮酒前后的动态心电图及心功能监测;戚平平 等;《实用心电学杂志》;20041231;第13卷(第2期);108-109 * |
| 蔬菜中的花色苷及其保健功能;吕锋 等;《中国食物与营养》;20071231(第3期);47-49 * |
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Inventor after: Wo Jinshan Inventor after: Guo Qunqun Inventor after: Zhao Chunyu Inventor after: Wu Shaojing Inventor after: Yu Chunyan Inventor after: Xiao Zhixiu Inventor after: Yu Ximeng Inventor after: Lv Shouqin Inventor before: Wo Jinshan Inventor before: Guo Qunqun Inventor before: Yu Chunyan Inventor before: Xiao Zhixiu Inventor before: Yu Ximeng Inventor before: Lv Shouqin |
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Effective date of registration: 20180307 Address after: 266000 Shandong city of Qingdao province Jimo City Lan Ao Lu Jimo District No. 1281 Hospital of traditional Chinese Medicine Applicant after: Zhang Haiyan Address before: 266071 Shandong city of Qingdao province Ningxia City Road No. 308 Applicant before: Qingdao University |
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